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Reproductive and Urinary Physiology Commons™
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Full-Text Articles in Reproductive and Urinary Physiology
Menstrual Cycle Phase Effects On Exercise Thermoregulation And Performance In The Heat, Kailei J. Eustis
Menstrual Cycle Phase Effects On Exercise Thermoregulation And Performance In The Heat, Kailei J. Eustis
All Master's Theses
Hormone fluctuations across the menstrual cycle (MC) may influence physiological responses. This study examined whether thermoregulatory measures differ across MC phases, and if these changes impact running performance in the heat. Ten eumenorrheic adults completed two treadmill runs in simulated conditions (wet bulb globe temperature 31.7 ± 1.4°C) during early follicular (EF) and midluteal (ML) phases. First 45min was a constant self-selected light pace followed by a 15min performance test for distance. Core temperature (Tc), mean skin temperature (Ts), heart rate (HR), perceived exertion (RPE), thermal perception (THERM), and comfort perception (COMF) were assessed every 5min. Sweat perception (SP), sweat …
Prenatal Androgen Exposure Reduces Ovarian Function, Marlee Weets
Prenatal Androgen Exposure Reduces Ovarian Function, Marlee Weets
All Master's Theses
Polycystic ovary syndrome (PCOS) is the most common reproductive and endocrine disorder, being the leading cause of infertility for females of reproductive age. The etiology of PCOS is not fully known, although it is hypothesized that there is a genetic, epigenetic, and environmental component to the disease. One of the environmental influences that can cause an abnormal reproductive phenotype similar to PCOS is prenatal exposure to excess androgens (male sex hormones). Previous studies have shown that prenatal exposure to androgens in mice can cause a PCOS-like ovarian phenotype similar to people with PCOS. To examine how prenatal androgen exposure causes …
The Hormonal Regulation Of The Claudin Genes In The Ovary, Sean Gadson, April Binder, Kenneth Korach, Katherine Hamilton
The Hormonal Regulation Of The Claudin Genes In The Ovary, Sean Gadson, April Binder, Kenneth Korach, Katherine Hamilton
All Master's Theses
The ovary is a dynamic organ that responds to many hormonal signals. When these hormonal signals are disrupted, ovarian dysfunction can occur. One such example is Polycystic Ovarian Syndrome (PCOS). PCOS patients suffer from high levels of testosterone. Excess testosterone may misregulate genes in the ovary and disrupt ovarian function. The Claudin (Cldn) 3 and Cldn11 genes have been shown to be regulated by androgens in the testis, while studies in ovarian cancer cells suggests a coregulatory mechanism for the expressions of Cldn3 and Cldn4 in the ovary. The objective of this study was to characterize the hormonal …