Neoplasms Commons^™

Beyond Drainage: Can Pleural Effusion Serve As A Natural Tamponade Against Tumor Hemorrhage? A Case Report And Mechanistic Hypothesis, Pratyush Kumar, Kumar Abhishek, Pankti Shah, Amelia Goslin, Archana Machavarapu, Catherine Joyce, Michael Waxman

MidAmerica Division GME Healthcare Symposium 2026

No abstract provided.

Retrospective Correlation Analysis Of Tumor Infiltrating Lymphocytes In Triple Negative Breast Cancer: Examining Associations With Tumor Grade, Histologic Grade, And Lymph Node Status At A Tertiary Hospital In The Philippines, John Paul Ladera, Duebrt Guererro

MidAmerica Division GME Healthcare Symposium 2026

No abstract provided.

Does Guideline-Directed Breast Mri Improve Early Identification In The High-Risk Breast Cancer Population, Cemile Littlepage

Doctor of Nursing Practice (DNP) Scholarly Projects

Introduction: In the United States, one in eight women will be diagnosed with breast cancer. The American Cancer Society's 2007 guidelines (Onishi & Kataoka, 2020) and the American College of Radiology recommend that MRI screening, alongside annual mammography, be used for women at high risk for breast cancer (Lamb et al., 2023; Sardanelli et al., 2024). Currently, there are various screening models, and no standardized tool or national guideline exists for MRI screening in high-risk patients. This guideline project aims to establish a screening model and recommendations for MRI screening in high-risk women for use in primary care.

Methods: A …

Cologuard, Call To Action! A Structured Outreach Intervention For Patients With Unreturned Cologuard Kits, Crystal Bharat, Sophia Zia, Harsh Bhatt, Abd Almasih Barbar Askar, Kulwinder Bhatnura, Dhruv Patel, Dennis Besong

South Atlantic Division GME Research Days 2026

No abstract provided.

Comprehensive Profiling And Clinical Utility Of Csf-Derived Cell-Free Dna/Rna For Evaluation Of Solid And Hematologic Malignancies Affecting The Central Nervous System, Renee Morecroft, Ryan Gimple, Maher Abitar, Omar Butt

South Atlantic Division GME Research Days 2026

No abstract provided.

The History We Didn't Hear: An M&M On Communication And Misinformation, Ansh Patel, Anjan Parghi

South Atlantic Division GME Research Days 2026

No abstract provided.

High-Grade Undifferentiated Sarcoma With Osteoclast-Like Giant Cells Mimicking A Pyogenic Granuloma, Shiv Patel, Tamara Fakhoury, Taha Rasul, Benjamin Cooper, Leila Parsa, Madeline Coleman, Alexandra Mathis, Karthik Krishnamurthy, Michelle Foley

South Atlantic Division GME Research Days 2026

No abstract provided.

Often Overlooked: Microbial Influence In Disease Progression Of Mycosis Fungoides, Alexis Coican, Angelia Stepien

South Atlantic Division GME Research Days 2026

No abstract provided.

Afx: Small Tumor, Big Personality, Alexandra Mathis, Abigail Lowe, Juan Rosario

South Atlantic Division GME Research Days 2026

No abstract provided.

Not Your Average Nodule: The Enigmatic Chondroid Syringoma, Alexandra Mathis, Clara Barranco, Joanna Mcgetrick, Karthik Krishnamurthy

South Atlantic Division GME Research Days 2026

No abstract provided.

Cutaneous Clues To Systemic Relapse In Alk-Negative, Cd30+ Anaplastic Large Cell Lymphoma, Leila Parsa, Angelia Stepien

South Atlantic Division GME Research Days 2026

No abstract provided.

Large Mesenteric Cyst Mimicking Dyspepsia In A Young Adult Female, Arjavon Talebzadeh, Hugo Barrera

South Atlantic Division GME Research Days 2026

No abstract provided.

A Case Of The Bone Pain: Differentiating Between Metastatic Prostate Cancer And Paget’S Disease Of The Bone, Manishea Veggal, Faris Mohamad

South Atlantic Division GME Research Days 2026

No abstract provided.

Utilization Of Multimodal Therapy Including Ketamine And Methadone In Cancer-Related Pain: A Case Report, Austin Mccrea, Carol Elsakr, Tyler Kilgore

South Atlantic Division GME Research Days 2026

No abstract provided.

A New Diagnosis Of Enteropathy Associated T-Cell Lymphoma In A Critically Ill Patient, Brooke Escoe, Riley Lovett, Reggie Skains Iii, Mohamed Faris

South Atlantic Division GME Research Days 2026

No abstract provided.

An Uncommon Cause Of Dyspnea And Peripheral Edema: A Giant Pleural Solitary Fibrous Tumor In A Young Adult, Reggie Skains Iii, Mikayla Kidd, Brooke Escoe, Vishal Shah

South Atlantic Division GME Research Days 2026

No abstract provided.

A Colonic Metastasis Of Breast Cancer Discovered During Routine Surveillance Colonoscopy: A Rare Case Report, Minh Nguyen, Brenden Pearce, Jayden Navarro, Brooke Escoe, Kathleen Raynor

South Atlantic Division GME Research Days 2026

No abstract provided.

Persistent Racial And Sex-Based Disparities In Radiation Receipt And Survival Among Patients With Anal Cancer, Yashaswi Koguru, Austin Mccrea, Stephen Meyer

South Atlantic Division GME Research Days 2026

No abstract provided.

One In A Hundred Million: Pseudomyxoma Peritonei Originating From An Ovarian Borderline Mucinous Tumor, Lilly Mcincrow, Michael Phillips, Samantha Perez, Tanner Fincher, Carolyn April

South Atlantic Division GME Research Days 2026

No abstract provided.

Primary Renal Lymphoma: A Rare Cause For Acute Renal Failure, Anish Sutaria, Phillip Bloodworth, Anjali Patel

South Atlantic Division GME Research Days 2026

No abstract provided.

When To Biopsy Incidentally Noted, Radiologically Relevant Lymph Nodes In Dcis, John B. Chiari, Jillian Giblin, Brooke Hassan, Katie Bennett

South Atlantic Division GME Research Days 2026

No abstract provided.

Rare Case Of Spontaneous Hepatocellular Carcinoma Regression, Anna Wiggins, Eleanora Stark, Cooper Alden Josephs

South Atlantic Division GME Research Days 2026

No abstract provided.

Spontaneous Hemidiaphragm Elevation, A Subtle, Early Sign Of Malignancy, Michael Lee Phillips, Caitlyn Brown, Rena Phillips, John Ashby, Chad Martins

South Atlantic Division GME Research Days 2026

No abstract provided.

An Unusual Cause Of Postpartum Bleeding: Choriocarcinoma Following Term Pregnancy, Erika R. Olsen, Sarah Hitt, James Burke

South Atlantic Division GME Research Days 2026

No abstract provided.

Investigating The Role Of Traditional Chinese Herbal Medicine For Cancer Symptom Management In Older Adults: A Rapid Review, Isabelle C. Karshner

Honors Undergraduate Theses

Background: Patients with cancer often experience symptoms related to disease, complications, and treatment. One potential method of alleviating these symptoms is traditional Chinese herbal medications (TCHM). This rapid review explores the role of traditional Chinese herbal medications in treating cancer-related symptoms in older adults.

Purpose: The purpose of this rapid review is to gain and provide a better understanding of the effects of TCHM on cancer-symptom management in the older adult population. This review explores the association between TCHM and effects on cancer symptoms in older adults, including interactions, toxicity, and signs/symptoms of TCHM use that may be useful information …

A Blood-Based Test For Colorectal Cancer Screening, Joshua Cullison

HCA Healthcare Journal of Medicine

Within the United States (US), colorectal cancer (CRC) remains the fourth most common malignancy and is responsible for over 50 000 deaths annually, second only to lung cancer in cancer mortality. Despite increased public awareness and increasing screening rates, the US remains far below the 80% screening mark set by the National Colorectal Cancer Roundtable at 59%. The addition of non-invasive blood-based tests for CRC screening could potentially increase screening rates and lower CRC deaths.

I performed a PubMed search using the search term “blood-based colorectal cancer screening.” I was particularly interested in articles that looked at Shield, which is …

Disruption Of Protein-Protein Interaction Hotspots In The C-Terminal Domain Of Mlh1 Confers Mismatch Repair Deficiency, Keri M. Fishwick, Diego Gomez Vieito, Giada Greco, Giulio Collotta, Marco Gatti, Anastasija A. Kulik, Raphaël Guérois, Ivan Corbeski, Ashutosh S. Phadte, Issam Senoussi, Petr Cejka, Anna Pluciennik, Antonio Porro, Alessandro A. Sartori

Department of Biochemistry and Molecular Biology Faculty Papers

MutLα, a heterodimer of MLH1 and PMS2, plays a key role in DNA mismatch repair (MMR), which maintains genomic stability by correcting replication errors. Loss of MLH1 function causes MMR deficiency (MMRd), leading to elevated mutation rates and increased cancer susceptibility. However, MMRd can offer a therapeutic advantage, as high tumour mutational burden enhances the efficacy of immune checkpoint inhibition. MMR also drives somatic expansion of CAG repeats linked to Huntington’s disease (HD) pathogenesis. The C-terminal domain (CTD) of MLH1 contains at least two distinct protein–protein interaction (PPI) sites. The S1 site supports heterodimerization with the PMS2 endonuclease, whereas the …

The Effect Of Neoadjuvant Chemoradiotherapy On Perioperative Outcomes In Rectal Cancer Patients Following Stoma Reversal-A Retrospective Cohort Analysis, Mary Junak, Rosemarie Turk, Mohammad Afaque Alam, Eli Thompson, David Schaub, Joseph Gunderson, Anesu S. Masango, Srikar Kollipara, Andrea Moreno, Daniom Tecle, Valentine N. Nfonsam

School of Medicine Faculty Publications

BACKGROUND: Anastomotic leak after reversal of an ostomy is a significant complication in rectal cancer patients. The effects of neoadjuvant chemoradiotherapy (NCRT) on outcomes following stoma reversal are not well established. The aim of our study was to evaluate the effect of NCRT on outcomes in rectal cancer patients following stoma reversal. METHODS: We performed a [2005-2012] retrospective cohort analysis of the American College of Surgeons-National Surgical Quality Improvement Program (ACS-NSQIP), including adult (≥18 years) rectal cancer patients who had elective stoma reversal. Patients were stratified into those who received NCRT and those who did not. Primary outcomes were anastomotic …

Inflammatory Co-Regulation Of Voltage-Gated Sodium Channels And Na,K-Atpase In Metastatic Breast Cancer, Steven D. Scahill, Kelly Jean Sherman, Dennis Paul

School of Graduate Studies Faculty Publications

Sodium regulation is a potentially major driver of cancer metastasis. Voltage-gated sodium channels (VGSCs) and Na,K-ATPase are sodium transporters that are upregulated in many advanced carcinomas and are implicated as metastatic drivers. However, little is known about what drives this overexpression, how these proteins influence metastatic behavior, or whether these complementary sodium transporters are co-regulated in cancer. Using sodium transporter regulation in healthy neurons as a model, the present study demonstrated that the inflammatory mediator tumor necrosis factor alpha (TNFα) affects the expression of VGSCs and Na,K-ATPase in an in vitro model of metastatic breast cancer. Acute TNFα challenge increased …

Metastatic Uveal Melanoma Surveillance: A Delphi Panel Consensus, Juan Alban, R. Christopher Bowen, David A. Reichstein, Meredith Mckean, Jose Lutzky, Ezekiel Weis, Richard D. Carvajal, Susan Dulka, Brian G. Morse, Marcus O. Butler, Suthee Rapisuwon, Kevin B. Kim, Sanjay Chandrasekaran, Allison Betof Warner, Jonathan S. Zager, Bartosz Chmielowski, Sapna P. Patel, Leonel Fernando Hernandez-Aya, Zelia M. Correa, Leslie A. Fecher, Yana G. Najjar, Kamaneh Montazeri, Alexander N. Shoushtari, Asad Javed, Dan S. Gombos, April K. S. Salama, Katy Tsai, Frank H. Miller, Nikhil Khushalani, Rino S. Seedor, Evan J. Lipson, Sunil A. Reddy, Elizabeth Buchbinder, Shailender Bhatia, Anna Pavlick, Inderjit Mehmi, Thomas Aaberg, Alexandra P. Ikeguchi, Ivana K. Kim, Scott D. Walter, Arun D. Singh, Ryan J. Sullivan, Jacob S. Choi, Basil K. Williams, Marlana Orloff, Prithvi Mruthyunjaya, Megan D. Schollenberger, Namita Gandhi, J. William Harbour, Sunandana Chandra

Department of Radiology Faculty Papers

BACKGROUND/OBJECTIVES: Uveal melanoma is a rare but aggressive intraocular malignancy that metastasizes in up to half of patients, most commonly to the liver, despite effective local treatment. In the absence of robust evidence, there are no standardized guidelines for post-treatment surveillance, resulting in wide variation in imaging modalities, frequency, and duration across physicians and institutions. This study aimed to develop expert consensus recommendations for surveillance strategies in patients with uveal melanoma.

METHODS: A modified Delphi method was conducted across three iterative survey rounds between September 2024 and February 2025 using an online platform. Panelists included medical oncologists, ocular oncologists, radiologists, …