Dentistry Commons^™

Xenograft Tumors Vascularized With Murine Blood Vessels May Overestimate The Effect Of Anti-Tumor Drugs: A Pilot Study, Zhihong Dong, Atsushi Imai, Sudha Krishnamurthy, Zhaocheng Zhang, Benjamin David Zeitlin, Jacques E. Nör

All Dugoni School of Dentistry Faculty Articles

Recent evidence demonstrated that endothelial cells initiate signaling events that enhance tumor cell survival, proliferation, invasion, and tumor recurrence. Under this new paradigm for cellular crosstalk within the tumor microenvironment, the origin of endothelial cells and tumor cells may have a direct impact on the pathobiology of cancer. The purpose of this pilot study was to evaluate the effect of endothelial cell species (i.e. murine or human) on xenograft tumor growth and response to therapy. Tumor xenografts vascularized either with human or with murine microvascular endothelial cells were engineered, side-by-side, subcutaneously in the dorsum of immunodefficient mice. When tumors reached …

Ada News - 12/09/2013, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Chhs December 2013 E-Newsletter, Dr. John Bonaguro, Dean, Vashon S. Wells, Editor, College Of Health And Human Services, Western Kentucky University

College of Health & Human Services Publications

No abstract provided.

Ada News - 11/18/2013, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Ada News - 11/04/2013, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Melorheostosis And Central Giant Cell Granuloma Of The Mandible In A 15-Year-Old Girl, Kenneth M. Anderson, W. H. Shintaku, Molly S. Rosebush, Yeshwant B. Rawal, E. S. Woodard

School of Dentistry Faculty Research and Publications

Melorheostosis is a nonhereditary bone dysplasia primarily affecting the appendicular skeleton. Because clinical and histologic features are often nonspecific, the diagnosis is often based on the radiographic presentation. Involvement of the craniofacial skeleton is rare. We describe a case of a 15-year-old girl with appendicular and craniofacial melorheostosis with adjacent central giant cell granuloma. We discuss the possible significance of this previously unreported finding.

Chhs November 2013 E-Newsletter, Vashon S. Wells, Editor, Dr. John Bonaguro, Dean, College Of Health & Human Services, Western Kentucky University

College of Health & Human Services Publications

No abstract provided.

Predictors Of Dental Care Use: Findings From The National Longitudinal Study Of Adolescent Health, Christopher Okunseri, Elaye Okunseri, Raul I. Garcia, Alexis D. Visotcky, Aniko Szabo

School of Dentistry Faculty Research and Publications

Purpose

To examine longitudinal trends and associated factors in dental service utilization by adolescents progressing to early adulthood in the United States.

Methods

The data source was the National Longitudinal Study of Adolescent Health from Waves I (1994–1995), II (1996), III (2001–2002), and IV (2007–2008). This was a retrospective, observational study of adolescents' transition to early adulthood. We obtained descriptive statistics and performed logistic regression analyses to identify the effects of baseline and concurrent covariates on dental service utilization from adolescence to early adulthood over time.

Results

Dental service utilization within the prior 12 months peaked at age 16 (72%), …

The Effect Of Water Storage On The Bending Properties Of Esthetic, Fiber-Reinforced Composite Orthodontic Archwires, Ju-Han Chang, David W. Berzins, Jessica E. Pruszynski, Richard W. Ballard

School of Dentistry Faculty Research and Publications

Objective: To study the effect of water storage on the bending properties of fiber-reinforced composite archwires and compare it to nickel-titanium (NiTi), stainless steel (SS), and beta-titanium archwires.

Materials and Methods: Align A, B, and C and TorQ A and B composite wires from BioMers Products, 0.014-, 0.016, and 0.018-inch, and 0.019 × 0.025-inch NiTi, 0.016-inch SS, and 0.019 × 0.025-inch beta-titanium archwires were tested (n  =  10/type/size/condition). A 20-mm segment was cut from each end of the archwire; one end was then stored in water at 37°C for 30 days, while the other was stored dry. The segments were …

Ada News - 10/21/2013, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Ada News - 10/07/2013, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Dental Student Debt In The U.S.: A Mountain To Be Scaled, David G. Dunning

Journal Articles: College of Dentistry

Dental student educational debt in the United States continues to grow as a concern for both dental educators and dental students. While certainly warranted, this concern needs to be understood from the perspective of return on investment. The student debt issue remains a critical one. However, this debt is essentially “good” debt when viewed as an investment made by associates/ employees of general dental practices and general dental practice owners.

Modulation Of The Effects Of Lung Immune Response On Bone Marrow By Oral Antigen Exposure, Pedro Xavier-Elsas, Cassio Luiz Coutinho Almeida-Da-Silva, L. Pinto, Túlio Queto, Bruno Marques Vieira, M. G. Aramha, Bianca De Luca, Daniela Masid-De-Brito, R. A. Luz, R. S. Lopes, R. Ferreira, Maria Ignez C. Gaspar-Elsas

All Dugoni School of Dentistry Faculty Articles

Allergic airway inflammation is attenuated by oral tolerization (oral exposure to allergen, followed by conventional sensitization and challenge with homologous antigen), which decreases airway allergen challenge-induced eosinophilic infiltration of the lungs and bone marrow eosinophilia. We examined its effects on bone marrow eosinophil and neutrophil production. Mice of wild type (BP-2, BALB/c, and C57BL/6) and mutant strains (lacking iNOS or CD95L) were given ovalbumin (OVA) or water (vehicle) orally and subsequently sensitized and challenged with OVA (OVA/OVA/OVA and H2O/OVA/OVA groups, resp.). Anti-OVA IgG and IgE, bone marrow eosinophil and neutrophil numbers, and eosinophil and neutrophil production ex vivo were evaluated. …

Ada News - 09/16/2013, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Ada News - 09/02/2013, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Nontraumatic Dental Condition-Related Visits To Emergency Departments On Weekdays, Weekends And Night Hours: Findings From The National Hospital Ambulatory Medical Care Survey, Christopher Okunseri, Elaye Okunseri, Melissa Christine Fischer, Saba Noori Sadeghi, Qun Xiang, Aniko Szabo

School of Dentistry Faculty Research and Publications

Objective: To determine whether the rates of nontraumatic dental condition (NTDC)-related emergency department (ED) visits are higher during the typical working hours of dental offices and lower during night hours, as well as the associated factors.

Methods: We analyzed data from the National Hospital Ambulatory Medical Care Survey for 1997 through 2007 using multivariate binary and polytomous logistic regression adjusted for survey design to determine the effect of predictors on specified outcome variables.

Results: Overall, 4,726 observations representing 16.4 million NTDC-related ED visits were identified. Significant differences in rates of NTDC-related ED visits were observed with 40%–50% higher rates during …

Chhs October 2013 E-Newsletter, Dr. John Bonaguro, Dean, Vashon S. Wells, Editor, College Of Health And Human Services, Western Kentucky University

College of Health & Human Services Publications

No abstract provided.

A Diffusible Mobile Dental Services Model For Prevention-Focused Outreach For Underserved Children In Rural Communities, Nikki Stone, Frances J. Feltner, Willie Bates

Center of Excellence in Rural Health Presentations

Background: In 2006 a mobile dental outreach program began operating full-time at the UK North Fork Valley Community Health Center in Hazard, Kentucky, a federally-qualified health center administered by the University of Kentucky and located at the UK Center of Excellence in Rural Health. This program continues to provide preventive dental care to children at forty different elementary schools and Head Start centers in a four county area of southeastern Kentucky located in the heart of rural Appalachia. The counties are Leslie, Knott, Letcher and Perry (LKLP), which are part of the Kentucky River Development District and encompass the LKLP …

A Phase I Trial Of Aminolevulinic Acid-Photodynamic Therapy For Treatment Of Oral Leukoplakia, Stuart J. Wong, Bruce Campbell, Becky Massey, Denis P. Lynch, Ezra E.W. Cohen, Elizabeth M. Blair, Rebecca Selle, Julia Shklovskaya, Borko D. Jovanovic, Silvia Skripkauskas, Alexander Dew, Peter Kulesza, Vamsi Parimi, Raymond C. Bergan, Eva Szabo

School of Dentistry Faculty Research and Publications

Background

Photodynamic therapy with aminolevulinic acid (ALA PDT) for oral leukoplakia has shown promising effects in regression of oral leukoplakia. Although ALA has been extensively studied and is an ideal photosensitizer, the optimal light dose for treatment of oral leukoplakia has not been determined. We conducted a phase I study to determine MTD and DLT of PDT in patients treated with ALA for leukoplakia.

Methods

Patients with histologically confirmed oral leukoplakia received a single treatment of ALA PDT in cohorts with escalating doses of light (585 nm). Clinical, histologic, and biologic markers were assessed.

Results

Analysis of 11 participants is …

Practice Based Dental Research - Advancing And Improving Dental Practice, Gary L. Stafford

School of Dentistry Faculty Research and Publications

No abstract provided.

Ada News - 08/19/2013, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Ada News - 08/05/2013, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Alfred Owre: Revisiting The Thought Of A Distinguished, Though Controversial, Early Twentieth-Century Dental Educator, David A. Nash

Oral Health Science Faculty Publications

Many in dental education are unfamiliar with the professional life and thought of Dr. Alfred Owre, a distinguished though controversial dental educator in the early twentieth century. Owre served as dean of dentistry at both the University of Minnesota, 1905-27, and Columbia University, 1927-33. He was also a member of the Carnegie Foundation's commission that developed the report Dental Education in the United States and Canada, written by Dr. William J. Gies. Owre was a controversial leader due to his creative and original ideas that challenged dental education and the profession. His assessment and critique of the problems of dental …

Ada News - 07/15/2013, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Racial And Ethnic Variations In Waiting Times For Emergency Department Visits Related To Nontraumatic Dental Conditions In The United States, Christopher Okunseri, Elaye Okunseri, Cesar A. Chilmaza, Shazeen Harunani, Qun Xiang, Aniko Szabo

School of Dentistry Faculty Research and Publications

Background

Researchers have documented an association between waiting times in emergency departments (EDs) and quality of care for medical conditions, but little is known about trends and factors associated with waiting times for ED visits related to nontraumatic dental conditions (NTDCs). The authors examined trends in waiting time and associated factors for NTDC-related ED visits in the United States.

Methods

The authors analyzed data from the National Hospital Ambulatory Medical Care survey for 1997 to 2007, excluding 2001 and 2002 owing to lack of information about waiting times. The authors used a survey-weighted linear regression of log-transformed waiting-time model to …

Chhs July E-Newsletter, Dr. John Bonaguro, Dean, Vashon S. Wells, Editor, College Of Health & Human Services, Western Kentucky University

College of Health & Human Services Publications

No abstract provided.

Comparative Evaluation Of Two Different Castable Bar Attachments In Implant Retained Mandibular Overdenture Cases, Fardos N. Rizk

Dentistry

Objective: This research was carried to evaluate which solitary attachment; OT Cap Ball attachment or OT Cap Equator Profile attachment mounted on a bar splinting two implants retaining mandibular overdenture is more favorable regarding crestal bone height and bone density changes surrounding the implants using cone beam computed tomography. Materials and Methods: Following two stage surgical protocol twelve completely edentulous patients received two implants placed bilaterally in the canine region (24 implants) to retain mandibular overdenture. Four months following the surgery patients were randomly divided into two equal groups; Group-I received two OT Cap Ball attachments mounted on a bar …

Ada News - 06/17/2013, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Ada News - 06/03/2013, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Oral Atypical Cellular Blue Nevus: An Infiltrative Melanocytic Proliferation, Brian S. Shumway, Yeshwant B. Rawal, Carl M. Allen, John R. Kalmar, Cynthia M. Magro

School of Dentistry Faculty Research and Publications

The atypical cellular blue nevus is an extremely rare nevomelanocytic lesion which lacks precise histologic characterization in the current literature. Given the potential for significant architectural and cytologic overlap with melanoma, further study, including molecular analysis, is needed. This is the first description of an atypical cellular blue nevus of the oral cavity.