Medicine and Health Sciences Commons^™

Regulation Of Microglial Activation In Stroke In Aged Mice: A Translational Study, Conelius Ngwa, Abdullah Al Mamun, Shaohua Qi, Romana Sharmeen, Yan Xu, Fudong Liu

Faculty, Staff and Student Publications

Numerous neurochemical changes occur with aging and stroke mainly affects the elderly. Our previous study has found interferon regulatory factor 5 (IRF5) and 4 (IRF4) regulate neuroinflammation in young stroke mice. However, whether the IRF5-IRF4 regulatory axis has the same effect in aged brains is not known. In this study, aged (18-20-month-old), microglial IRF5 or IRF4 conditional knockout (CKO) mice were subjected to a 60-min middle cerebral artery occlusion (MCAO). Stroke outcomes were quantified at 3d after MCAO. Flow cytometry and ELISA were performed to evaluate microglial activation and immune responses. We found aged microglia express higher levels of IRF5 …

Nine Out Of Ten Samples Were Mistakenly Switched By The Orang-Utan Genome Consortium, Graham L Banes, Emily D Fountain, Alyssa Karklus, Robert S Fulton, Lucinda Antonacci-Fulton, Joanne O Nelson

2020-Current year OA Pubs

The Sumatran orang-utan (Pongo abelii) reference genome was first published in 2011, in conjunction with ten re-sequenced genomes from unrelated wild-caught individuals. Together, these published data have been utilized in almost all great ape genomic studies, plus in much broader comparative genomic research. Here, we report that the original sequencing Consortium inadvertently switched nine of the ten samples and/or resulting re-sequenced genomes, erroneously attributing eight of these to the wrong source individuals. Among them is a genome from the recently identified Tapanuli (P. tapanuliensis) species: thus, this genome was sequenced and published a full six years prior to the species' …

The Impact Of Psychosocial Stress On Maternal Health Outcomes: A Multi-State Prams 8 (2016-2018) Analysis, Blessing Chidiuto Lawrence, Anna Kheyfets, Keri Carvalho, Shubhecchha Dhaurali, Marwah Kiani, Alison Moky, Ndidiamaka Amutah-Onukagha

Journal of Health Disparities Research and Practice

Introduction: Significant racial disparities persist in maternal morbidity rates, disproportionately affecting Black women. Experiencing high levels of stress during pregnancy is associated with increased risk for preterm birth, infant mortality, and preeclampsia. This study investigates the impact of psychosocial life stressors on maternal morbidity and racial disparities utilizing the Pregnancy Risk Assessment Monitoring System (PRAMS) dataset.

Methods: Participants (N=24,209) included were from Phase 8 (2016-2018) of the PRAMS survey across five states. Stressors were grouped into traumatic, partner-related, financial, or emotional. Maternal outcomes included gestational diabetes, hypertensive disorders of pregnancy, prenatal depression, and postpartum depression. The association between life stressors …

From A Place Of Love: The Experiences Of Birthing In A Black-Owned Culturally-Centered Community Birth Center, J'Mag Karbeah, Rachel Hardeman, Numi Katz, Dimpho Orionzi, Katy Kozhimannil

Journal of Health Disparities Research and Practice

Introduction: Racial and ethnic disparities in perinatal health outcomes are among the greatest threats to population health in the United States. Black birthing communities are most impacted by these inequities due to structural racism throughout society and within health care settings. Although multiple studies have shown that structural racism and the disrespect associated with this system of inequity are the root causes of observed perinatal inequities, little scholarship has centered the needs of Black birthing communities to create alternative care models. Leaning on reproductive justice and critical race theoretical frameworks, this study explores good birth experiences as described by Black …

Moving Towards Justice: Reducing Encounters Of Preeclampsia In Adolescent Maternal Health, Shaunesse' Jacobs Plaisimond, George Hodulik, Molly Wilde

Journal of Health Disparities Research and Practice

Using data from the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be (nuMoM2b), several relationships were explored between nutrition and diet, likely attributed to education, culture, training, and habits around food. While these factors remain relevant and worth pursuing, data analysis implied that the most significant issue remaining is access to healthcare. Across race, age, and nutrition consumption, if pregnant people make higher incomes—inferring better access to healthcare and higher-quality nutrients, then their risk of preeclampsia is reduced. Accordingly, this paper performs an extensive literature review of the intersection of extreme maternal age and nutrient intake as a significant factor for preeclampsia. …

Defining Birth Equity In Kansas, Oluoma Obi, Michelle L. Redmond, Joi Wickliffe, Sapphire Garcia-Lies, Sharla Smith

Journal of Health Disparities Research and Practice

Background: While some health outcomes improve in the United States, racial and ethnic disparities in pregnancy-related outcomes persist. In the United States and Kansas, Black women are three times more likely to die from a pregnancy-related complication than white women.

Description: The Kansas Birth Equity Network (KBEN), is an initiative developed to address racial disparities in maternal and child health outcomes. We used a community-centered approach to collect stakeholder perceptions of birth equity and develop a case definition of birth equity.

Methods: An open-ended online survey was designed to collect stakeholders’ definition of birth equity, their organization’s birth equity missions, …

Birth Justice Philly: Equitable Community Engagement In Action, Simone N. Snead, Imani Davis, Samantha Shuster, Elizabeth Guman, Cynthia Estremera Gauthier, Aasta D. Mehta

Journal of Health Disparities Research and Practice

This article describes how a multi-sector coalition focusing on carrying out recommendations of the Philadelphia Maternal Mortality Review Committee (MMRC) engages community participation through the development of equitable strategies that culminate in the implementation of actionable methods to improve perinatal outcomes.

The U.S. maternal mortality crisis continues to impact countless families and communities. Despite having some of the finest academic medical centers in the nation and a functioning county-level maternal mortality review committee, the maternal mortality rate in Philadelphia, Pennsylvania is far above the national average. Vital statistics show that Philadelphia’s rate of pregnancy-related deaths from 2012 to 2018 was …

Addressing Racial Disparities In Maternal Health: The Case For An Equity Birth Plan, Alice Trye, Damali Campbell Oparaji, Natalie Roche, Lisa Gittens Williams

Journal of Health Disparities Research and Practice

Birth equity can be defined as “The assurance of the conditions of optimal births for all people with a willingness to address racial and social inequities in a sustained effort.” (Birth Equity |California Maternal Quality Care Collaborative, n.d.). Complex explanations exist for adverse maternal outcomes, but unequal health care, socioeconomic and racial inequalities pose risks to women and their babies (“Unequal Treatment: Confronting Racial and Ethnic Disparities in Health Care,” 2003). The data is clear: Maternal death rates have increased and are 3 to 4 times higher for black women than white women (Zaharatos et al., 2018). These …

Editor's Notes, Nekeshia Jones, Sharla Smith, Melva Thompson-Robinson

Journal of Health Disparities Research and Practice

These Editors' Notes introduce the first special issue of the Journal of Health Disparities Research and Practice based on the work the National Maternal Health Research Network.

2022 James B. Erdmann Award Recipients

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

Jefferson Center for Interprofessional Practice and Education (JCIPE) congratulates this year’s interprofessional education (IPE) and collaborative practice (CP) award winners and thanks them for all their efforts to support and advance this work on campus and beyond. Their contributions are immeasurable!

Reflections On Jcipe’S Interprofessional Palliative Care Program, Brian Donnelly Bsn

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

JCIPE’s Interprofessional Palliative Care Program is a semester-long learning collaborative in which small interprofessional student teams learn about the team-based provision of palliative care for persons with serious illness and at the end of life. Using the National Consensus Project’s Clinical Practice Guidelines for Quality Palliative Care as a framework, teams work collaboratively through case-based discussions and presentations. Additionally, participants have an opportunity to observe Jefferson’s Palliative Care Team’s interdisciplinary rounds and to shadow a Jefferson palliative care provider.

Curricular Revision And Assessment Of Undergraduate Interprofessional Education, Erin Choice Phd, Cscs, Shelene Thomas Pt, Dpt, Edd, Gcs, Fnap

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

College students who desire a career in the health professions, begin their discovery of professional scope through their undergraduate programs. Currently, there lacks uniformity in undergraduate curricula in knowledge, skills and behaviors necessary for collaborative practice in future healthcare systems (Aldriwesh et al., 2022).

Raising The Bar: Evolution Of A Statewide Interprofessional Education Program Following A 5-Year Outcomes Evaluation, Brittany J. Daulton Phd, Ms, Zachary A. Weber Pharmd, Bcps, Bcacp, Cdces, Fash, April D. Newton Pt, Dpt, Ma, Fnap, Laura Romito Dds, Ms, Mba, Fnap, Barbara Manz Friesth Phd, Rn

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

Indiana University is a complex campus system across the state of Indiana. IU-Bloomington hosts the main campus with nearly 50,000 students, while Indiana University-Purdue University Indianapolis (IUPUI) has approximately 30,000. Additionally, there are seven regional medical school campuses located throughout the state in Gary, Evansville, Fort Wayne, Muncie, South Bend, Terre Haute, and West Lafayette.

Meet An Ipe Student Champion From Thomas Jefferson University, Meredith Gray Ost

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

I had the opportunity to work with two JCIPE programs as a Graduate Assistant – Team Care Planning (TCP) and Enhancing Services for Homeless Populations (ESHP). Team Care Planning involves interprofessional groups of students participating in a simulated discharge planning meeting with a standardized patient. For TCP, I analyzed data from simulation sessions to identify common themes that students discuss when reflecting on their simulation experience. I also worked with the Team Care Planning team to put together materials to market TCP to other universities. Enhancing Services for Homeless Populations is a virtual simulation program utilizing the program Second Life …

Meet An Ipe Faculty Champion From Thomas Jefferson University, Jeannette Kates Phd, Crnp, Agpcnp-Bc, Gnp-Bc

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

I have the privilege of working with JCIPE in several ways. I am currently faculty co-lead for Alzheimer’s Virtual Interprofessional Training (AVIT) and faculty lead for the new Interprofessional Palliative Care Program. Additionally, I have had the opportunity to participate in other JCIPE programs by facilitating for Introductory TeamSAFE and the Health Mentors Program.

Micro-Credentials In Ipe: The Ipe Path Of Distinction And Badger Programs In University Of Wisconsin-Madison, Hossein Khalili Bscn, Mscn, Phd, Fnap, Susan Wenker Pt, Phd, Laura Birkeland Ms, Cgc, Meghan Cotter Phd, Benjamin Weber Ma, Mb, (Ascp)Cm, Julia Schiller Spt, Roberta Rusch Mph

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

The UW CIPE Badger Program is a branch of the UW–Madison Badger program in which we provide focused IPE academic training, called IPE Badges, with fewer academic requirements than a typical degree and/or certificate program. IPE Badges are formal, virtual, micro-credentials issued to learners (students, faculty, staff, or practitioners) who participate in and successfully complete designated IPE offerings and activities at UW–Madison and its partners.

Jcipe Updates

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

JCIPE Updates

From The Editors

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

We’re so excited to share this Spring/ Summer edition of our newsletter! As the academic year comes to a close, we look back on another year filled with ups and downs, incredible accomplishments and ongoing challenges. Life during the COVID-19 pandemic has changed. Relative widespread vaccination and declining mortality and hospitalization rates have allowed a slow return to prior routines and activities for many. Yet infection rates are still on the rise as we continue to mourn the lives lost to COVID in the U.S. and globally, and grapple with its prolonged impact. For many of us, COVID has highlighted …

Collaborative Healthcare: Interprofessional Practice, Education And Evaluation (Jcipe), Volume 12, Number 3, Spring/Summer 2022

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

In this Issue:

• Letter from the Editors
• JCIPE Update
• Micro-Credentials In IPE: The IPE Path of Distinction and Badger Programs in University of Wisconsin-Madison
• Meet an IEP Faculty Champion
• Meet an IPE Student Champion
• Raising the Bar: Evolution of a Statewide Interprofessional Education Program Following a 5-Year Outcomes Evaluation
• Curricular Revision and Assessment of Undergraduate Interprofessional Education
• Reflections on JCIPE's Interprofessional Palliative Care Program
• 2022 James B. Erdmann Award Recipients

Vis/Nir Spectra And Color Parameters According To Leaf Age Of Some Eucalyptus Species: Influence On Their Classification And Discrimination, Izabel P. Migacz, Jane Manfron, Paulo V. Farago, Vijayasankar Raman

Faculty and Student Publications

Aim of study: The aim of this study was to verify the differences in VIS/NIR spectra and leaf color parameters of leaves of Eucalyptus badjensis, E. benthamii, E. dunnii, E. grandis, E. globulus and E. saligna, at four ages, and their influence on species discrimination. Area of study: São Mateus do Sul, Paraná, Brazil. Materials and methods: Seedlings of the six species, with four replicates for each, were acclimatized in the same environment, in Oc-tober 2015, in an entirely randomized design. Leaf samples were collected from plants that were 6, 8, 10 and 12 months old. Three leaves from each …

Why Is Blood Glucose Control Important To Self-Care Of Pregnant Women With Gestational Diabetes Mellitus?, Mi-Joon Lee, Bum Jeun Seo, Yeon Sook Kim

Nursing Faculty Publications

This study aimed to investigate the change in self-care, self-efficacy, and health status of pregnant women with gestational diabetes mellitus (GDM), and to identify whether blood glucose control influences pregnancy outcomes. This study is experimental research using a one-group pretest-posttest design. The study subjects were 40 pregnant women diagnosed with GDM, and the data were collected in their 24th and 40th week of gestation and analyzed using SPSS 27.0. Paired samples t-test was used to compare the health status, self-care, and self-efficacy of subjects between antepartum and postpartum, and t-test and non-parametric test were used to evaluate the changes in …

Sexual Behaviours And Sexual Health Among Middle-Aged And Older Adults In Britain, Junead Khan, Emily Greaves, Clare Tanton, Hannah Kuper, Thomas Shakespeare, Eneyi Kpokiri, Yun Wang, Jason J. Ong, Suzanne Day, Stephen W. Pan, Weiming Tan, Bingyi Wang, Xin Peng, Bowen Liang, Huachun Zou, Joseph D. Tucker, Dan Wu

Pharmacy Faculty Articles and Research

Objectives Population-representative studies of the sexual health of middle-aged and older adults are lacking in ageing societies. This study aimed to identify latent patterns of sexual behaviours and health of people aged 45–74 years.

Methods We conducted a latent class analysis of the National Attitudes and Sexual Lifestyles Survey (Natsal-3), a nationally representative survey conducted in Britain in 2011.

Results Of the 5260 respondents aged 45–74 years, 48.86% of men and 44.91% of women belonged to the Content Caseys class who reported good sexual health. The Infrequent Indigos (30.94% of men, 44.38% of women) were characterised by a lack of …

The Role Of Occupational Therapy In Unplanned Motherhood, Cierra Stewart, Karen Park

Summer 2022 Virtual OTD Capstone Symposium

For women experiencing unplanned pregnancy, the thought of becoming a mother can increase stress and affect the mother’s mental health. Maternal adjustment can include depression, anxiety, worry, stress, and happiness (Mihelic et al., 2016). The impact that this new role has effects daily demands, leading to a disruption in occupational engagement, environmental changes, and overall less time for the mother (Horne et al., 2005). There is currently not a well-defined role for occupational therapy within pregnancy medical clinics to support women experiencing unplanned pregnancy and their transition to motherhood. The purpose of this project is to provide care to new …

Occupational Therapy's Role In Athletic Retirement, Diana Mellin, Karen Park, Madison Harris

Summer 2022 Virtual OTD Capstone Symposium

Athletic retirement is described as a life transition involving withdrawal from the athletic role. Throughout the process of athletic retirement, individuals experience a loss of identity, roles, routines, and social support which has shown to negatively impact their overall mental health and well-being (Marterella & Smoot, 2017). This study investigated elite athletes’ experiences throughout their transition to athletic retirement, a ten-question online survey and semi-structured interviews were administered. Themes that emerged from the data are occupational adjustment and relearning roles, experiencing a crossroads of identity, external expectations, and pressures. Participants shared experiencing a period of burnout and detachment right after …

Risk Of Transmission Of Respiratory Viruses During Aerosol-Generating Medical Procedures (Agmps) Revisited In The Covid-19 Pandemic: A Systematic Review, Jenine Leal, Brenlea Farkas, Liza Mastikhina, Jordyn Flanagan, Becky Skidmore, Charleen Salmon, Devika Dixit, Stephanie Smith, Stephen Tsekrekos, Bonita Lee, Joseph Vayalumkal, Jessica Dunn, Robyn Harrison, Melody Cordoviz, Roberta Dubois, Uma Chandran, Fiona Clement, Kathryn Bush, John Conly, Oscar Larios

Faculty, Staff and Student Publications

BACKGROUND: In many jurisdictions healthcare workers (HCWs) are using respirators for aerosol-generating medical procedures (AGMPs) performed on adult and pediatric populations with all suspect/confirmed viral respiratory infections (VRIs). This systematic review assessed the risk of VRIs to HCWs in the presence of AGMPs, the role respirators versus medical/surgical masks have on reducing that risk, and if the risk to HCWs during AGMPs differed when caring for adult or pediatric patient populations.

MAIN TEXT: We searched MEDLINE, EMBASE, Cochrane Central, Cochrane SR, CINAHL, COVID-19 specific resources, and MedRxiv for English and French articles from database inception to September 9, 2021. Independent …

Comparing Outcomes For Community-Acquired Pneumonia Between Females And Males: Results From The University Of Louisville Pneumonia Study, Pavani Nathala, Simrat Sarai, Vidyulata Salunkhe, Mahder A. Tella, Stephen P. Furmanek, Forest W. Arnold

The University of Louisville Journal of Respiratory Infections

Introduction: Male sex is currently considered to be a risk factor for worsened community-acquired pneumonia (CAP) outcomes compared to female sex; hence, female sex equates to a lower score on the Pneumonia Severity Index. There is no recent update on sex-based outcomes of patients with CAP. The objective of this study was to compare the outcomes of CAP between females and males.

Methods: This was a secondary analysis of the University of Louisville Pneumonia Study database. It was a prospective population-based cohort study of all hospitalized adults with CAP who were residents of Jefferson County in the city of Louisville, …

Maternal Proximity To Mountain-Top Removal Mining And Birth Defects In Appalachian Kentucky, 1997–2003, Daniel B. Cooper, Courtney J. Walker, W. Jay Christian

Epidemiology and Environmental Health Faculty Publications

Extraction of coal through mountaintop removal mining (MTR) alters many dimensions of the landscape. Explosive blasts, exposed rock, and coal washing have the potential to pollute air and water. Previous research suggests that infants born to mothers living in areas with MTR have a higher prevalence of birth defects. In this cross-sectional study, we further examine the relationship between MTR activity and several types of birth defects. Maternal exposure to MTR was assessed using remote sensing data from Skytruth, which captures MTR activity in the Central Appalachian region of the United States. Active MTR area was quantified within a five-kilometer …

Navigating Care Transitions For Older Adults In The Emergency Department When A Social Worker Is Unavailable, Rebecca Weeks, Kathy Sawasky, Adam Perry, Michael Malone

Journal of Geriatric Emergency Medicine

Some Emergency Departments do not have social worker staffing to assess high- risk older adults who have been identified. This is of particular concern in during care transitions for older patients who are at risk for poor health outcomes. We describe triggers for the emergency provider to recognize older patients at high risk and bundles of appropriate services and community supports to mitigate risk.

Supporting Rural Seniors Aging In Place Using Telehealth, Angel Alexander Gomez, Susan Macdermott

Summer 2022 Virtual OTD Capstone Symposium

Background: The United States is witnessing a demographic shift in that the number of Americans aged 65 and older is projected to nearly double from 52 million in 2018 to 95 million by 2060; the percentage of the 65 and older age group will increase from 16 % to 23 % (Administration for Community Living, 2018). In this ever-growing population, the American Association of Retired Persons (AARP) 2018 survey found that 76% of Americans over the age of 50 would prefer to remain in their current residence and 77% would like to continue living in their community as long as …

Transportation As A Barrier To Healthcare Access For Older Adults Of Low Socioeconomic Status, Yanira Barajas, Susan Macdermott, Jazminne Orozco Arteaga

Summer 2022 Virtual OTD Capstone Symposium

The older adult population of those in the age group 65+ is one of the fastest growing populations in the following years. This project sought to identify what barriers older adults of low socioeconomic status face when trying to access transportation to healthcare appointments. The project also sought to understand what barriers healthcare professionals saw when their senior clients tried using transportation as well as what opportunities occupational therapists have to address the barriers if any. There was a theme of disconnect which appeared between healthcare professionals and their senior clients across multiple healthcare disciplines. This project was able to …