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2022

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Full-Text Articles in Medicine and Health Sciences

2022-12-14_Michiganoverview_Covidvaccinestats, Michigan Department Of Health & Human Services Dec 2022

2022-12-14_Michiganoverview_Covidvaccinestats, Michigan Department Of Health & Human Services

Michigan COVID-19 Vaccine Data

The COVID Vaccine Dashboard page was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus/resources/covid-19-vaccine/covid-19-dashboard.

First-dose tracker above is for entire Michigan Population. Coverage maps below are for age 5+.

Previously reported numbers of administered vaccine doses may change as new data are received. A possible lag in reporting vaccine doses will result in increases in numbers previously reported.

This report is created by the Michigan Department of Health and Human Services Division of Immunization from data reported to the Michigan Care Improvement Registry (MCIR).

The dashboard contained the tabs Primary Series Doses Administered, Primary Series Doses by Vaccine, …


Train To Move: A Sensory Approach To Functional Fitness To Promote Movement And Play In Youth, Eboni Rowe, Lisa Griggs-Stapleton Dec 2022

Train To Move: A Sensory Approach To Functional Fitness To Promote Movement And Play In Youth, Eboni Rowe, Lisa Griggs-Stapleton

Fall 2022 Virtual OTD Capstone Symposium

The Center for Disease and Control (2022) have implemented guidelines for over a decade suggesting a recommended amount of daily physical activity, however a high proportion of children and adolescents in the United States are physically inactive (Mitchell, 2019). Encouraging lots of movement and play can help build a strong foundation in which children understand that being physically active can and should be a healthy habit throughout their lives. Incorporating use of sensory-based occupational therapy can provide a fun and enjoyable approach to functional fitness and promote movement and play, especially for youth who may have special sensory needs. Therefore, …


Comparison Of Clinical And Biomechanical Characteristics Between Individuals With Lower Limb Amputation With And Without Lower Back Pain: A Systematic Review And Meta-Analysis, Szu-Ping Lee, Shawn Farrokhi, Jenny A. Kent, Jason Ciccotelli, Lung-Chang Chien, Jo Armour Smith Dec 2022

Comparison Of Clinical And Biomechanical Characteristics Between Individuals With Lower Limb Amputation With And Without Lower Back Pain: A Systematic Review And Meta-Analysis, Szu-Ping Lee, Shawn Farrokhi, Jenny A. Kent, Jason Ciccotelli, Lung-Chang Chien, Jo Armour Smith

Physical Therapy Faculty Articles and Research

Background

Lower back pain is a debilitating condition common to individuals with lower limb amputation. It is unclear what risk factors contribute to the development of back pain. This study systematically reviewed and analyzed the available evidence regarding the clinical and biomechanical differences between individuals with amputation, with and without lower back pain.

Methods

A literature search was conducted in PubMed, Web of Science, Scopus, and CINAHL databases in November 2020 and repeated in June 2021 and June 2022. Studies were included if they reported comparisons of demographic, anthropometric, biomechanical, and other clinical variables between participants with and without LBP. …


The Mediating Effect Of Caregiving Relationship Quality On The Association Between Caregiving Stressors And Mental Health Problems Among Older Spousal Caregivers, Fei Wang, Elliane Irani Dec 2022

The Mediating Effect Of Caregiving Relationship Quality On The Association Between Caregiving Stressors And Mental Health Problems Among Older Spousal Caregivers, Fei Wang, Elliane Irani

Faculty Scholarship

Providing care to a spouse can be especially challenging for older adults given their compounding stressors resulting from aging and caregiving. This cross-sectional study examines the relationships between caregiving stressors and caregiver mental health problems and the potential mediator (i.e., caregiving relationship quality) of these associations. A total of 431 Americans (≥65 years) were selected from the National Study of Caregiving. Path analysis shows that care assistance was positively associated with caregiver mental health problems, and this association was mediated by negative relationship quality (Indirect effect =.14, p =.016). Moreover, role overload was positively associated with caregiver mental health problems, …


Detection Of Stroke With Retinal Microvascular Density And Self-Supervised Learning Using Oct-A And Fundus Imaging, Samiksha Pachade, Ivan Coronado, Rania Abdelkhaleq, Juntao Yan, Sergio Salazar-Marioni, Amanda Jagolino, Charles Green, Mozhdeh Bahrainian, Roomasa Channa, Sunil A Sheth, Luca Giancardo Dec 2022

Detection Of Stroke With Retinal Microvascular Density And Self-Supervised Learning Using Oct-A And Fundus Imaging, Samiksha Pachade, Ivan Coronado, Rania Abdelkhaleq, Juntao Yan, Sergio Salazar-Marioni, Amanda Jagolino, Charles Green, Mozhdeh Bahrainian, Roomasa Channa, Sunil A Sheth, Luca Giancardo

Faculty, Staff and Student Publications

Acute cerebral stroke is a leading cause of disability and death, which could be reduced with a prompt diagnosis during patient transportation to the hospital. A portable retina imaging system could enable this by measuring vascular information and blood perfusion in the retina and, due to the homology between retinal and cerebral vessels, infer if a cerebral stroke is underway. However, the feasibility of this strategy, the imaging features, and retina imaging modalities to do this are not clear. In this work, we show initial evidence of the feasibility of this approach by training machine learning models using feature engineering …


Investigating The Relationships Between Concentrated Disadvantage, Place Connectivity, And Covid-19 Fatality In The United States Over Time, Fengrui Jing, Zhenlong Liu, Shan Qiao, Jiajia Zhang Ph.D., Bankole Olatosi Ph.D., Xiaoming Li Ph.D. Dec 2022

Investigating The Relationships Between Concentrated Disadvantage, Place Connectivity, And Covid-19 Fatality In The United States Over Time, Fengrui Jing, Zhenlong Liu, Shan Qiao, Jiajia Zhang Ph.D., Bankole Olatosi Ph.D., Xiaoming Li Ph.D.

Faculty Publications

Background Concentrated disadvantaged areas have been disproportionately affected by COVID-19 outbreak in the United States (US). Meanwhile, highly connected areas may contribute to higher human movement, leading to higher COVID-19 cases and deaths. This study examined the associations between concentrated disadvantage, place connectivity, and COVID-19 fatality in the US over time. Methods Concentrated disadvantage was assessed based on the spatial concentration of residents with low socioeconomic status. Place connectivity was defined as the normalized number of shared Twitter users between the county and all other counties in the contiguous US in a year (Y = 2019). COVID-19 fatality was measured …


Interprofessional Education Lab Manual And Workbook, Geraldine Terry Dec 2022

Interprofessional Education Lab Manual And Workbook, Geraldine Terry

Open Textbooks

This laboratory manual was designed to educate and develop integrated healthcare practices essential in delivering person-centered care. Participants will develop their ability to distinguish the role of their own profession and other healthcare professionals collaborating in the care coordination and case management of patients. The content and team-oriented activities in this manual provide guidance on advancing leadership and communication principles necessary for effective interprofessional communication and team collaboration. The well-researched material is tailored to build on the strengths of participants, while also identifying and encouraging areas for improvement.


Pyrvinium Pamoate: Past, Present, And Future As An Anti-Cancer Drug, Christopher W Schultz, Avinoam Nevler Dec 2022

Pyrvinium Pamoate: Past, Present, And Future As An Anti-Cancer Drug, Christopher W Schultz, Avinoam Nevler

Department of Surgery Faculty Papers

Pyrvinium, a lipophilic cation belonging to the cyanine dye family, has been used in the clinic as a safe and effective anthelminthic for over 70 years. Its structure, similar to some polyaminopyrimidines and mitochondrial-targeting peptoids, has been linked with mitochondrial localization and targeting. Over the past two decades, increasing evidence has emerged showing pyrvinium to be a strong anti-cancer molecule in various human cancers in vitro and in vivo. This efficacy against cancers has been attributed to diverse mechanisms of action, with the weight of evidence supporting the inhibition of mitochondrial function, the WNT pathway, and cancer stem cell renewal. …


Advice From One Patient To Another: Qualitative Analysis Of Patients' Perspectives About Chemotherapy Initiation, Catalina Malinowski, Edna Paredes, Ashley J Housten, Mariana Chavez-Macgregor Dec 2022

Advice From One Patient To Another: Qualitative Analysis Of Patients' Perspectives About Chemotherapy Initiation, Catalina Malinowski, Edna Paredes, Ashley J Housten, Mariana Chavez-Macgregor

2020-Current year OA Pubs

PURPOSE: Although the association between delays in (neo)adjuvant chemotherapy initiation and adverse outcomes is well-documented, patient perspective regarding the lived experience among those with breast cancer delay is sparse. Project Start was a qualitative study designed to assess and identify the multilevel factors contributing to the barriers and facilitators of initiating chemotherapy. This report explores specific responses where patients with breast cancer provide insight and advice for newly diagnosed women on preparing for chemotherapy initiation and informs potential interventions to facilitate timely chemotherapy initiation.

PATIENTS AND METHODS: Women diagnosed with primary invasive breast cancer who experienced a ≥60-day delay in …


Social Attention During Object Engagement: Toward A Cross-Species Measure Of Preferential Social Orienting, Claire Weichselbaum, Nicole Hendrix, Jordan Albright, Joseph D Dougherty, Kelly N Botteron, John N Constantino, Natasha Marrus Dec 2022

Social Attention During Object Engagement: Toward A Cross-Species Measure Of Preferential Social Orienting, Claire Weichselbaum, Nicole Hendrix, Jordan Albright, Joseph D Dougherty, Kelly N Botteron, John N Constantino, Natasha Marrus

2020-Current year OA Pubs

BACKGROUND: A central challenge in preclinical research investigating the biology of autism spectrum disorder (ASD) is the translation of ASD-related social phenotypes across humans and animal models. Social orienting, an observable, evolutionarily conserved behavior, represents a promising cross-species ASD phenotype given that disrupted social orienting is an early-emerging ASD feature with evidence for predicting familial recurrence. Here, we adapt a competing-stimulus social orienting task from domesticated dogs to naturalistic play behavior in human toddlers and test whether this approach indexes decreased social orienting in ASD.

METHODS: Play behavior was coded from the Autism Diagnostic Observation Schedule (ADOS) in two samples …


A Gating Lever And Molecular Logic Gate That Couple Voltage And Calcium Sensor Activation To Opening In Bk Potassium Channels, Liang Sun, Frank T Horrigan Dec 2022

A Gating Lever And Molecular Logic Gate That Couple Voltage And Calcium Sensor Activation To Opening In Bk Potassium Channels, Liang Sun, Frank T Horrigan

Faculty, Staff and Students Publications

BK channels uniquely integrate voltage and calcium signaling in diverse cell types through allosteric activation of their K+-conducting pore by structurally distinct V and Ca2+ sensor domains. Here, we define mechanisms and interaction pathways that link V sensors to the pore by analyzing effects on allosteric coupling of point mutations in the context of Slo1 BK channel structure. A gating lever, mediated by S4/S5 segment interaction within the transmembrane domain, rotates to engage and stabilize the open conformation of the S6 inner pore helix upon V sensor activation. In addition, an indirect pathway, mediated by the carboxyl-terminal cytosolic domain (CTD) …


Single Cell Rna Sequencing Of The Adult Drosophila Eye Reveals Distinct Clusters And Novel Marker Genes For All Major Cell Types, Kelvin Yeung, Komal Kumar Bollepogu Raja, Yoon-Kyung Shim, Yumei Li, Rui Chen, Graeme Mardon Dec 2022

Single Cell Rna Sequencing Of The Adult Drosophila Eye Reveals Distinct Clusters And Novel Marker Genes For All Major Cell Types, Kelvin Yeung, Komal Kumar Bollepogu Raja, Yoon-Kyung Shim, Yumei Li, Rui Chen, Graeme Mardon

Faculty, Staff and Students Publications

The adult Drosophila eye is a powerful model system for phototransduction and neurodegeneration research. However, single cell resolution transcriptomic data are lacking for this tissue. We present single cell RNA-seq data on 1-day male and female, 3-day and 7-day old male adult eyes, covering early to mature adult eyes. All major cell types, including photoreceptors, cone and pigment cells in the adult eye were captured and identified. Our data sets identified novel cell type specific marker genes, some of which were validated in vivo. R7 and R8 photoreceptors form clusters that reflect their specific Rhodopsin expression and the specific Rhodopsin …


Potential Risks Inherent In Robotic Process Automation, Colin L. Robinson, David Y. Chan Dec 2022

Potential Risks Inherent In Robotic Process Automation, Colin L. Robinson, David Y. Chan

Journal of Vincentian Social Action

Robotic process automation (RPA) uses automation technologies to perform tasks typically performed by humans. Although such technology has been instrumental in expediting business operations and lowering costs, it has also created several risks that warrant scrutiny. When discussing the drawbacks of automation, many will point to the number of jobs lost to the influx of automation. However, there are technology risks that organizations must consider such as fraud and cybersecurity. Fraudsters may utilize RPA to commit more novel and subtle technological and cyber security fraud. Organizations may implement internal control measures to prevent or mitigate such schemes, segregation of duties, …


Consumer Boycotts In The Time Of War Crisis: An Efficient Citizenship Strategy Or A Temporary Spurt Of Solidarity, Jolanta Zralek Dec 2022

Consumer Boycotts In The Time Of War Crisis: An Efficient Citizenship Strategy Or A Temporary Spurt Of Solidarity, Jolanta Zralek

Journal of Vincentian Social Action

By drawing from the theory of consumer citizenship, collective activism, and consumer boycotts, this article strives to understand the nature of the current calls for consumer resistance and the following consumers’ actions that resulted from the Russian invasion of Ukraine. In particular, by utilizing Friedman’s (1991) taxonomy of boycotts, we aimed to identify the character, motives, and tools of ongoing boycotts and thus estimated their actual and probable effectiveness. The main research questions in this paper concern what type of consumer boycotts we currently observe, what the aims and motives are of current boycotting, and whether the noticed boycotting attempts …


Leveraging Next-Gen Technology For Supply Chain Security, Thomas Drape, Reginald P. Parker Dec 2022

Leveraging Next-Gen Technology For Supply Chain Security, Thomas Drape, Reginald P. Parker

Journal of Vincentian Social Action

Global supply chain disruptions continue as part of both a national and global discussion. There is a need for a greater focus on supply chain security as part of this discussion as there is an increasing amount of counterfeit parts and goods within global supply chains. While counterfeit activity is an economic burden to companies and the global market, there are also legitimate concerns on consumer safety, consumer trust and company brand management.

The aim for this paper is to identify the concern and extent of the counterfeit problem and identify the use of next-gen technologies to provide brand protection …


Sustainability Across The Supply Chain: A Case Study In The Automotive Industry, Jane Siegler, Angelyn Bidlack, Sarah Harrison Dec 2022

Sustainability Across The Supply Chain: A Case Study In The Automotive Industry, Jane Siegler, Angelyn Bidlack, Sarah Harrison

Journal of Vincentian Social Action

The United Nations Sustainable Development Goals have been widely adopted and implemented by organizations worldwide. However, with 17 goals and 169 targets, the decision on what to focus on and invest in are not trivial tasks. This research focuses on a major Tier-1 automotive supplier, here identified as CMF. With annual sales of 16 billion euros (2021), one in every three vehicles in the world is equipped with some form of CMF technology. The objective of this research was to evaluate CMF’s value chain and understand the challenges and opportunities related to the United Nations 17 Sustainability Development Goals (SDGs). …


Covid-19 And Culture: Individualism Versus Collectivism, Short-Term Versus Long-Term Orientation, And Indulgence Versus Restraint, Charles Lanier, Navpreet Pooni Dec 2022

Covid-19 And Culture: Individualism Versus Collectivism, Short-Term Versus Long-Term Orientation, And Indulgence Versus Restraint, Charles Lanier, Navpreet Pooni

Journal of Vincentian Social Action

To some degree, all social behaviors may be affected by cultural influences. So which national cultures could be positive influences or negative influences on the prevention of a contagion? (Roser et al., 2020). This paper explores regression models for predicting initial Covid-19 cases per capita by country utilizing only Hofstede’s six Cultural Dimensions (Hofstede et al., 2010).

Regression techniques were applied to develop predictive models for initial Covid-19 rates. Two proposed models were found that explained 54% and 60% of the variability in numbers of initial Covid-19 cases by country: The first model included only Individualism, and the second included …


Study Of The Impact Of Working At Home And The Fears Of Returning To Work Among Managers And Professionals Who Are In Virtual Congruent Jobs And Who Are High Growth/Achievement Oriented, Carmine Gibaldi, Gerald Cusack, Niall Hegarty Dec 2022

Study Of The Impact Of Working At Home And The Fears Of Returning To Work Among Managers And Professionals Who Are In Virtual Congruent Jobs And Who Are High Growth/Achievement Oriented, Carmine Gibaldi, Gerald Cusack, Niall Hegarty

Journal of Vincentian Social Action

Using two surveys, this article examines employee opinions on working from home during the Covid-19 pandemic. In March 2020 we chronicled the experience and reactions of 478 managers and professionals to the mandate they work at home. We found that a large portion of the respondents felt no significant loss in productivity and no reduction in job satisfaction. Most of the challenges they faced had involved efforts required to establish a facilitating home working environment and disruptions in the ease of collaboration with others. The opportunities overwhelmingly focused on the benefits of having more time to rebalance their work and …


Economic Implications Of State-Wide Covid-19 Response Aggressiveness, Bryan Foltice, Michael Edward Parker Dec 2022

Economic Implications Of State-Wide Covid-19 Response Aggressiveness, Bryan Foltice, Michael Edward Parker

Journal of Vincentian Social Action

This paper aims to evaluate how the aggressiveness of each state’s response to the Covid-19 pandemic affected their respective economies from Q2, 2020 through Q2, 2021. In our study, we utilize the scale developed by McCann (2021, April 6), which ranks the least aggressive state response to the most aggressive state response at three different points of the pandemic. Through this methodology, we test the impact of the aggressiveness of each state governments’ response with the resulting economic impact within that state. Namely, we examine how this level of response affected each state’s unemployment rate, gross domestic product growth, and …


Building A Better Future: Restoration, Resilience, And Sustainability, Biagio Pilato, Igor Tomic Dec 2022

Building A Better Future: Restoration, Resilience, And Sustainability, Biagio Pilato, Igor Tomic

Journal of Vincentian Social Action

No abstract provided.


Toc Dec 2022

Toc

Journal of Vincentian Social Action

No abstract provided.


Editors Dec 2022

Editors

Journal of Vincentian Social Action

No abstract provided.


Cover Dec 2022

Cover

Journal of Vincentian Social Action

No abstract provided.


2022 December 13 - Medical Student Education Committee Minutes, Medical Student Education Committee, East Tennessee State University Dec 2022

2022 December 13 - Medical Student Education Committee Minutes, Medical Student Education Committee, East Tennessee State University

Medical Student Education Committee Minutes

No abstract provided.


2022-12-13_Michiganoverview_Covidlongtermcare, Michigan Department Of Health & Human Services Dec 2022

2022-12-13_Michiganoverview_Covidlongtermcare, Michigan Department Of Health & Human Services

Michigan COVID-19 Long Term Care Data

The COVID Long Term Care Facilities page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/stats/data-about-places/long-term-care-data.

This report is created by the Michigan Department of Health & Human Services from data self-reported by long-term care facilities into EMResource. Data for all reporting facilities is posted weekly each Monday.

The information below represents COVID-19 data reported directly to MDHHS by licensed and operating Skilled Nursing, Home for the Aged and Adult Foster Care facilities (licensed to serve 13 or more individuals) in Michigan from January 1, 2020. All long-term care facilities additionally have an obligation to report COVID-positive residents and/or staff …


2022-12-13_Michiganoverview_Covidcounts, Michigan Department Of Health & Human Services Dec 2022

2022-12-13_Michiganoverview_Covidcounts, Michigan Department Of Health & Human Services

Michigan COVID-19 Confirmed Cases by Date of Onset Data

Data was downloaded as an Excel spreadsheet which appeared in the Public Use Datasets section under the Cumulative Data link of Michigan's Coronavirus webpage, under the url https://www.michigan.gov/coronavirus/stats.

Cases are aggregated by the date of onset of COVID-19 symptoms, if known, otherwise by laboratory specimen date if known, otherwise by case referral date. Deaths are aggregated by the date of death if known, otherwise by the last date of a change to the case status.


2022-12-13_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services Dec 2022

2022-12-13_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus/stats.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled. COVID case and testing data will be posted once a week on Tuesdays.

This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time polymerase chain reaction (NAAT/RT-PCR) …


The Traumatic Injuries Distress Scale: Manual And Questionnaire, David Walton Dec 2022

The Traumatic Injuries Distress Scale: Manual And Questionnaire, David Walton

Physical Therapy Publications

No abstract provided.


The Association Of The G8 Questionnaire With Treatment Side Effects And Unscheduled Care Among Older Breast Cancer Patients: A Retrospective Cohort Study, Sameh Gomaa, Louis Cappelli, Kristine Swartz, Tingting Zhan, Andrew Chapman, Ana Maria Lopez, Joseph Lombardo, Kuang-Yi Wen Dec 2022

The Association Of The G8 Questionnaire With Treatment Side Effects And Unscheduled Care Among Older Breast Cancer Patients: A Retrospective Cohort Study, Sameh Gomaa, Louis Cappelli, Kristine Swartz, Tingting Zhan, Andrew Chapman, Ana Maria Lopez, Joseph Lombardo, Kuang-Yi Wen

Department of Medical Oncology Posters

Introduction

  • Nearly half of the patients diagnosed with breast cancer are ≥ 65 years.
  • Older patients with breast cancer are at higher risk for experiencing treatment side effects and unplanned health care.
  • This can compromise treatment outcomes and increase the cost of care.
  • The G8 is among the most sensitive screening tools for frailty and mortality.
  • The aim of this study is to evaluate the association of the G8 questionnaire with treatment side effects and unscheduled care in older breast cancer women.


2022-12-13_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services Dec 2022

2022-12-13_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus/stats/coronavirus-symptoms. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated twice a week on Mondays and Thursdays.

Syndromic Surveillance System data is obtained from approximately 216 facilities participating in syndromic surveillance (139 Emergency Departments (ED), 77 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, …