Medicine and Health Sciences Commons^™

Blood-Brain Barrier Opening In A Large Animal Model Using Closed-Loop Microbubble Cavitation-Based Feedback Control Of Focused Ultrasound Sonication, Chih-Yen Chien, Lu Xu, Christopher Pham Pacia, Yimei Yue, Hong Chen

2020-Current year OA Pubs

Focused ultrasound (FUS) in combination with microbubbles has been established as a promising technique for noninvasive and localized Blood-brain barrier (BBB) opening. Real-time passive cavitation detection (PCD)-based feedback control of the FUS sonication is critical to ensure effective BBB opening without causing hemorrhage. This study evaluated the performance of a closed-loop feedback controller in a porcine model. Calibration of the baseline cavitation level was performed for each targeted brain location by a FUS sonication in the presence of intravenously injected microbubbles at a low acoustic pressure without inducing BBB opening. The target cavitation level (TCL) was defined for each target …

Sars-Cov-2, Long Covid, Prion Disease And Neurodegeneration, Yuhai Zhao, Vivian R. Jaber, Walter J. Lukiw

School of Medicine Faculty Publications

No abstract provided.

Plasma Protein Biomarkers For Primary Graft Dysfunction After Lung Transplantation: A Single-Center Cohort Analysis, Lourdes Chacon-Alberty, Rupa S Kanchi, Shengbin Ye, Camila Hochman-Mendez, Daoud Daoud, Cristian Coarfa, Meng Li, Sandra L Grimm, Maher Baz, Ivan Rosas, Gabriel Loor

Faculty, Staff and Students Publications

The clinical use of circulating biomarkers for primary graft dysfunction (PGD) after lung transplantation has been limited. In a prospective single-center cohort, we examined the use of plasma protein biomarkers as indicators of PGD severity and duration after lung transplantation. The study comprised 40 consecutive lung transplant patients who consented to blood sample collection immediately pretransplant and at 6, 24, 48, and 72 h after lung transplant. An expert grader determined the severity and duration of PGD and scored PGD at T0 (6 h after reperfusion), T24, T48, and T72 h post-reperfusion using the 2016 ISHLT consensus guidelines. A bead-based …

Meeting The Challenges Of Myocarditis: New Opportunities For Prevention, Detection, And Intervention-A Report From The 2021 National Heart, Lung, And Blood Institute Workshop, Daniela Čiháková, Yang Shi, Bishow Adhikari, W Patricia Bandettini, Madeleine W Cunningham, Narasimhan Danthi, Matthias G Friedrich, Peter Liu, Lisa Schwartz Longacre, Douglas L Mann, Filip K Swirski, W H Wilson Tang, Guofei Zhou, Leslie T Cooper Jr., Workshop Speakers

2020-Current year OA Pubs

The National Heart, Lung, and Blood Institute (NHLBI) convened a workshop of international experts to discuss new research opportunities for the prevention, detection, and intervention of myocarditis in May 2021. These experts reviewed the current state of science and identified key gaps and opportunities in basic, diagnostic, translational, and therapeutic frontiers to guide future research in myocarditis. In addition to addressing community-acquired myocarditis, the workshop also focused on emerging causes of myocarditis including immune checkpoint inhibitors and SARS-CoV-2 related myocardial injuries and considered the use of systems biology and artificial intelligence methodologies to define workflows to identify novel mechanisms of …

A Retrospective Study On Use Of Palliative Care For Patients With Alcohol Related End Stage Liver Disease In United States, Kamesh Gupta, Bandhul Hans, Ahmad Khan, Syed Hamza Sohail, Devika Kapuria, Chris Chang

2020-Current year OA Pubs

BACKGROUND: Palliative care (PC) has been shown to be beneficial in end stage liver disease (ESLD), yet the hospitalization data for PC utilization is unknown.

AIM: To identify the trend of PC utilization for the special population of alcohol-associated ESLD patients, factors affecting its use and ascertain its impact on healthcare utilization.

METHODS: We analyzed around 78 million discharges from the 2007-2014 national inpatient sample and 2010-2014 national readmission database including adult patients admitted for decompensated alcohol-associated cirrhosis. We identified patients with PC consultation as a secondary diagnosis. Odds ratios (OR) and means were adjusted for confounders using multivariate regression …

The Potential Role Of Selected Body Composition Phenotypes In The Interpretation Of The Exercise-Induced Components Of The Insulin-Like Growth Factor Systems, Gökhan Umutlu, Nevzat Demirci

Baltic Journal of Health and Physical Activity

Introduction: Increased adiposity leads to impaired physiologic growth hormone secretion and low and high body mass index (BMI) values increase health risks. However, BMI only measures results in variations in fat-free mass (FFM), fat-free mass index (FFMI), normalized fat-free mass index (NFMI), and body fat mass (BFM). This study evaluated the insulin-like growth factor system responses to the given exercise and their interaction with the changes in BMI, FFM, FFMI, and NFFMI in healthy male participants. Material and methods: A randomized controlled trial with a parallel groups study design was used. Thirty healthy male participants (age: 21.33 ±1.24 years) were …

Quantitative And Qualitative Criteria For Assessing Gait Speed In Women Aged 60–75 Years – A Pilot Study, Zbigniew Ossowski

Baltic Journal of Health and Physical Activity

Introduction: The use of the Gait Speed (GS) test in clinical practice has been documented in many scientific studies. However, there is a lack of tools to use the aforementioned test for diagnosis and follow-up of changes in the process of health training in postmenopausal women. Having considered the foregoing, the main objective of this study was to develop quantitative and qualitative criteria to assess gait speed in women aged 60–75 years. Material and methods: Sixty women aged 60–75 years participated in the study. The structure of the gait speed rating scale was based on Zaciorski's model. The data collected …

Salivary Molecules As Indicators Of Hydration Status, José Meléndez-Gallardo Dr., Mariana Figueroa, Gonzalo Butti, Mauro Iriart, María Lucía Stefanelli

Baltic Journal of Health and Physical Activity

Introduction: Maintaining an appropriate level of hydration is essential to health, especially when doing physical exercise. Thus, the importance of monitoring the before, during and after exercise status. Therefore, knowing and studying the changes and indicators that may provide reliable information on fluctuations in a simple, quick manner, via non-invasive sampling techniques becomes essential. Material and Methods: The data analyzed and processed (α-amylase, K⁺, Cl^-, cortisol, total protein, and osmolality concentration in saliva) in this study are available on the free access research platform for complex physiological signals (https://physionet.org/content/qde/1.0.0/). Ten male subjects voluntarily took part in …

Occupational Therapy Students' Perceptions Of Their Own Notetaking, Marie-Christine Potvin, Monique C. Chabot, Kathleen Carr

Internet Journal of Allied Health Sciences and Practice

Purpose: Notetaking is a critical skill for higher-level thinking and information integration in graduate students, including occupational therapy students. Though there is a growing body of literature about notetaking modalities, strategies utilized, and self-perceptions of skills in college students, studies about occupational therapy (OT) students’ notetaking preferences have been absent from the literature. This study examines how OT students take notes and their perceptions of their notes. Method: This descriptive study of students in a Master of Occupational Therapy program (n=57) completed the Notetaking Abilities and Strategies of University Students (NASUS) questionnaire which captures the constructs of notetaking methods, reasons …

Gender Microaggression And Macroaggression Experiences Of Women Athletic Trainers, Kara L. Trella, Kenneth E. Games, Justin P. Young, Matthew J. Drescher, Lindsey E. Eberman

Internet Journal of Allied Health Sciences and Practice

Purpose: Although gender disparities and workplace vitality for women has been studied in athletic training, gender discrimination has not been widely studied. The purpose of this study was to describe gender-based aggressions experienced by women athletic trainers (ATs) within their educational and workplace environments. Methods: We used a cross-sectional design, and the web-based survey was comprised of demographic questions, the Schedule of Sexism Events (SSE), and questions on incident reporting. The SSE asks participant to rank items on a Likert Scale (1 = the event never happened to 6 = the event happens almost all the time). Items within …

Influence Of Years Of Experience On Clinical Competence Of Novice Physical And Occupational Therapists In Japan, Hiroaki Sakurai, Soichiro Koyama, Shigeo Tanabe, Kazuya Takeda, Yoshikiyo Kanada

Internet Journal of Allied Health Sciences and Practice

Purpose: To increase the clinical competence of novice physical and occupational therapists, an accurate assessment of their clinical competence is necessary. However, no previous study has objectively analyzed the changes in novice therapists’ clinical competence in Japan. Hence, this study investigated and evaluated the changes in the clinical competence of such therapists using an objective analysis. Method: The study included 34 novice therapists with 1–3 years of experience in clinical practice. Participants were divided into groups according to their years of experience. The clinical competence of the novice therapists was evaluated twice using a clinical competency evaluation scale. For comparison …

Screening For Color Vision Deficiency In Health Science Students, Deborah A. Johnson, Jon Judge, Beverly J. Barham

Internet Journal of Allied Health Sciences and Practice

Purpose: Various professions require employees to be able to detect different shades of color accurately when visually reading test results with colorimetric end points. To prepare health science students to better meet this requirement, a screening test for color vision deficiency (CVD) was administered to detect any major or minor errors as part of the undergraduate student experience. Method: Screening for color vision deficiency was administered using the Farnsworth D-15 Color Vision Test. Students completed the test and their results were scored and interpreted at the time of completion. Results: Students (n=85) from nine different health science programs completed …

Introducing A Physical Therapist-Led Acceptance And Commitment Therapy Training For Pain: A Clinical Perspective, Joseph Tatta

Internet Journal of Allied Health Sciences and Practice

Purpose: Mounting evidence supports the use of cognitive and behavioral techniques as part of physical therapist practice. These methods are used within a physical therapist’s multimodal treatment approach for the management of pain and to facilitate health behavior change. There is a multitude of evidence-based cognitive behavioral techniques to choose from including newer approaches based on Acceptance and Commitment Therapy. Yet few studies have examined physical therapists’ perceptions to learning and implementing ACT into clinical practice. The purpose of this manuscript is to present a clinical perspective of physical therapists learning about and incorporating Acceptance and Commitment Therapy in clinical …

Experiences Participating In Online Synchronous Lectures During Covid-19 Emergency Remote Teaching For First- And Non-First-Generation Students, Michael F. Iorio, Timothy L. Seavey, Benjamin J. Becerra

Internet Journal of Allied Health Sciences and Practice

Background: During the COVID-19 pandemic, emergency remote teaching (ERT) was implemented in the U.S., and some of the most vulnerable college students struggled to adapt. Purpose: The current study sought to understand the experiences and outcomes of undergraduate students enrolled in radiography programs while participating in synchronous online lectures during ERT, especially first-generation students. Specifically, this study focused on students who participated in class lectures that were taught online in a live and synchronous format due to COVID-19 stay-at-home orders. Methods: This study utilized a retrospective and longitudinal design where participants were asked to answer a series …

Attitudes Toward Covid-19 And Covid-19 Vaccinations Among Athletic Trainers, Stephen A. Cage, Paul Mcgaha, Monica Matocha, Michelle Crum, Phd, Cathy Fieseler, Laurel Trail, Brandon J. Warner, Diana M. Gallegos

Internet Journal of Allied Health Sciences and Practice

Purpose: Following the beginning of the pandemic brought about by the novel coronavirus which causes COVID-19, the first COVID-19 vaccination received emergency use authorization in the United States of America in December of 2020. Current research has shown the authorized COVID-19 vaccines are safe and effective at preventing severe illness, hospitalizations and death have a good safety profile. Additionally, the side effects associated with these vaccines are typically mild to moderate while the protection against hospitalization and severe disease is substantial. (https://www.cdc.gov/coronavirus/2019-ncov/vaccines/safety/adverse-events.html). At the time of this study, there appears to be a paucity in the research related …

An Examination Of Emotional Resilience Among Athletic Trainers Working In The Secondary School Setting, Shaine Henert, William Pitney, Bethany Wood, Nicholas E. Grahovec, Tyler A. Wood

Internet Journal of Allied Health Sciences and Practice

Purpose: Athletic training is a demanding profession that is a stressor for many practitioners. Emotional resilience allows Athletic Trainers (ATs) to persist in their roles and benefit from long and successful careers. The purpose of this study was to explore the level of emotional resilience of ATs working in secondary school settings and identify factors perceived to contribute to or mitigate one's emotional resilience. Method: A sequential explanatory mixed-method design using a cross-sectional online survey followed by in-depth interviews was used to gather information from 160 (16% response rate) secondary school NATA members - 97 (60.6%) female; 63 (39.4%) male …

Case-By-Collaboration: An Adaptable Soft Skills-Based Educational Model For Health Disciplines, Elizabeth Gockel Blessing, Tyler A. Wood, Nicholas E. Grahovec

Internet Journal of Allied Health Sciences and Practice

Purpose: The purpose of this study was two-fold and consisted of the development of a skills-based model for Case-by-Collaboration (CBC) and the collection of qualitative data from students and teachers aimed at answering the research question: What skills do individuals (students) apply during the completion of a hypothetical medical laboratory management-based Case-by-Collaboration capstone project? Method: A consensual qualitative research design was selected for this study. Students and their instructors from three Medical Laboratory Science programs located in Texas, New York, and Missouri were recruited. Students were given a case that centers on the fictitious Cheapskate Health Maintenance Organization (HMO). The …

Translation, Cross-Cultural Adaptation, Reliability, And Validity Of The Tamil Version Of Fear-Avoidance Beliefs Questionnaire In Chronic Low Back Pain, Hasini Dayalan, P. Antony Leo Aseer, Soundararajan K

Internet Journal of Allied Health Sciences and Practice

Background: Excessive fear of movement, restricted physical activity, and cognitive distortions are frequently found with chronic low back pain (CLBP) subjects. The Fear-Avoidance Beliefs Questionnaire (FABQ) is the most well-founded and often used tool to measure fear and avoidance beliefs in CLBP subjects. In India, there is a diversity of culture, educational level, and language. So, there is a need to translate FABQ into the regional language Tamil, which will improve understanding of FABQ and reduce the language barrier of the Tamil population. Objective: To translate, cross-cultural adapt, and investigate the psychometric properties of the Tamil version of FABQ in …

Dietetic Student Involvement In A Sports Nutrition Education Program For University Athletes, Taylor Paeth, Diana Cuy Castellanos, Rebecca Gonter-Dray, Karyn Catrine

Internet Journal of Allied Health Sciences and Practice

Objectives: The purpose of this study is to examine the impact of a sports nutrition counseling experiential learning opportunity on self-efficacy and nutrition counseling skills in the undergraduate dietetic students and dietary goal adherence in collegiate athlete clients after receiving the student-led nutrition counseling intervention. Methods: This mixed methods design, using a thematic analysis and pre- and post-testing, was implemented at a mid-sized university in the Midwestern United States. There were fifteen undergraduate dietetic students and nine collegiate athletes. Results: Counseling confidence in the dietetic students improved significantly from session one to session three (p < 0.001). Conclusions and Implications: Similar …

The Clinical Reasoning Assessment Tool For Learning From Standardized Patient Experiences: A Pilot Study, Mary A. Riopel, Sara Benham, Jennifer Landis, Stephanie Falcone, Sarah Harvey

Internet Journal of Allied Health Sciences and Practice

Purpose: Clinical reasoning (CR) is the ability to integrate the knowledge of diagnoses with the use of supporting theories to create effective, client-centered interventions. One means of teaching CR to rehabilitation students is using standardized patient (SP) experiences. The relationship between faculty and student CR ratings after SP experiences has not been researched. The purpose of the study was to determine if there would be correlations between physical therapy (PT) and occupational therapy (OT) student and faculty ratings of CR skills after an SP experience. Method: The Clinical Reasoning Assessment Tool (CRAT) was used by students to self-reflect on their …

Assessment Of Inter-Instrument Reliability For Dominant Handgrip Dynamometry And Spirometry, Nnamdi Mgbemena, Anne Jones, Anthony Leicht

Internet Journal of Allied Health Sciences and Practice

Purpose: The aim of this study was to determine the inter-instrument reliability of different dynamometers and spirometers commonly used in clinical practice. Methods: The study involved 113 healthy volunteers across three facility sites. At each site, dominant handgrip strength (DHGS), and lung function (forced expiratory volume in one second [FEV₁], forced vital capacity [FVC] and peak expiratory flow rate [PEFR]), were compared using a local and reference device. Assessments were randomized with five minutes rest between measurements. Significant differences between devices were assessed using paired t-test while relative reliability between devices was determined via intra-class correlations (ICC). Accuracy …

Assessment And Diagnostic Practices Relating To Autism Spectrum Disorder In The United States And Mexico, Maria Valdez, Jessica R. Stewart, Wan-Lin Chang, Ruth Crutchfield, Ralph Carlson

Internet Journal of Allied Health Sciences and Practice

Purpose: The present study examined and compared professional assessment and diagnostic practices relating to autism spectrum disorder (ASD) in Mexico and the United States (U.S.). This information is of great importance because there is an extremely limited amount of information pertaining the assessment and diagnostic practices for ASD in Mexico and little is known about how these practices compare to those in the U.S. Methods: Archival data from a survey investigating ASD in the U.S. and Mexico was used for this study. Participants included 29 professionals from the U.S. and 7 professionals from Mexico. Professionals were from a variety of …

Health Profession Student’S Readiness Towards Online Learning As A Component Of Blended Learning, Narasimman Swaminathan, Latha Ravichandran, Ramachandran Sivakumar, Steve Milanese

Internet Journal of Allied Health Sciences and Practice

Objectives: The objectives of this study were to identify the entry-level health profession students’ perception and readiness to adopt online learning as a component of blended learning (BL). Methods: A cross sectional survey using a structured questionnaire was administered using Google forms. Entry level Health professionals’ education (HPE) graduate students of a higher education institute in India completed the survey (N= 628). The questionnaire was developed from the literature and content validated by experts. Ethics clearance was obtained from the Institutional ethics committee. Results: Out of 628 responses, 603 fully completed questionnaires were included for analysis. Of the participants, 98 …

Remote Job Application Simulation Using Technology In Athletic Training Students: A Preliminary Teaching Technique, Kevin M. Schroeder, Jamie Mansell, Dani Moffit

Internet Journal of Allied Health Sciences and Practice

While athletic training students go through extensive preparations for engaging with patient populations as healthcare providers, less time is spent on preparing athletic training students on how to secure employment after graduation. Without proper employment skills development, securing employment can pose a challenge for the athletic training student trying to enter the workforce. These skills include developing cover letters and resumes, and remote interviewing skills. Purpose: The purpose of this paper is to explore the preparations, execution, and lessons learned from a simulated, remote job application and interview process for athletic training students. Methods: This educational technique was performed using …

Characteristics Needed To Transition From Exemplary Clinical Instructor To Successful Site Coordinator Of Clinical Education: A Qualitative Study, Nicki Silberman, Vicki Lafay

Internet Journal of Allied Health Sciences and Practice

Introduction: In physical therapist (PT) education, the site coordinator of clinical education (SCCE) administers and manages clinical placements for student clinical education experiences from the clinical side. Characteristics of successful site coordinators of clinical education (SCCEs) have been established; minimal evidence informs the identification of individuals with those characteristics. One cannot assume that exemplary clinical instructors (CIs) will become effective SCCEs. Purpose: The purpose of this qualitative study was to investigate if the characteristics of exemplary CIs are consistent with the traits needed in a successful SCCE candidate by exploring these 3 aims: (1) Describe characteristics of exemplary CIs. (2) …

Correlates Of Caffeinated Energy Drinks, Substance Use, And Behavior Among Adolescents, Lauren N. Maziarz, Lauren A. Dial, Bradley Fevrier, William Ivoska

Internet Journal of Allied Health Sciences and Practice

Background: Caffeinated energy drinks (CCEDs) are frequently consumed by adolescents aged 10-19, yet the effects of consumption on adolescent behavior are not well understood. Previous research has identified positive associations between CCED use and other substances such as alcohol and marijuana but studies among adolescents are lacking. Methods: We conducted a secondary analysis using data collected from the 2019 Alcohol, Drug Addition, and Mental Health Services (ADAMHS) Board/Wood County Educational Service Center’s youth survey. Ten public schools in Wood County, Ohio participated (n=6,152). Results: CCED use was common among our sample (43.4% overall). Reported consumption increased with age and was …

The Predictive Relationship Between Psychological Capital And Academic Burnout In Postgraduate Students, Benjamin M. Radack, Theodus Luckett Iii, Wade W. Fish, Gary P. Austin

Internet Journal of Allied Health Sciences and Practice

Purpose: The purpose of this quantitative correlational study was to determine if, or to what extent, the composite and sub-composite categories of Psychological Capital (PsyCap) predict academic burnout in American postgraduate health science students at a university in the Southeastern United States. Methods: The variables of the study were measured by the Psychological Capital Questionnaire (PCQ-24) and the Maslach Burnout Inventory-Student Survey (MBI-SS). A convenience sampling method was used to collect data from the target population, which included a final sample of 90 health science postgraduate students. Results: A simple linear regression analysis revealed that PsyCap was a significant …

Adolescent Athletes’ Perspectives On The Social Implications Of Sport-Related Concussion, Tamara C. Valovich Mcleod, Justin S. Disanti, Richelle M. Williams, Cailee E. Welch Bacon

Internet Journal of Allied Health Sciences and Practice

Purpose: Sport-related concussion can affect many domains of a patient’s health status. Social functioning is an important consideration, especially for adolescent athletes. Our purpose was to explore adolescent athletes’ social perspectives regarding sport and concussion. Methods: Using a qualitative study design we interviewed 12 interscholastic athletes who had sustained a sport-related concussion. The interviews focused on injury details, and explored the physical, psychosocial, emotional, and spiritual components of sport and health. Themes and categories were identified using the consensual qualitative research process by a three-person research team. A comprehensive codebook that captured the main themes and categories resulted. Results: Following …

Body Composition And Psychophysical Well-Being Of Women Practicing Yoga, Aneta Omelan, Justyna Wiśniewska, Robert Podstawski

Baltic Journal of Health and Physical Activity

Introduction: This study characterized yoga as a form of free-time physical activity by analyzing and evaluating the body composition of women who regularly practice yoga, and by describing the effect of yoga on their psychophysical health. Material and Methods: The study involved 94 women: 56 yoga practitioners and 38 Zumba participants. The subjects were surveyed with a questionnaire to elicit information about their socioeconomic status. Body composition was determined by bioelectrical impedance analysis. Differences were assessed with two-tailed chi-square tests and Student’s t-tests. Results: The vast majority of the participants (89%) felt a positive influence of yoga on their mental …

Relationship Between Lower Limb Power Output, Sprint And Change Of Direction Performance In Soccer Players., Monika Papla, Agata Latocha, Wojciech Grzyb, Artur Gołaś

Baltic Journal of Health and Physical Activity

Introduction: Although soccer matches require players to perform repetitive power-related abilities, the impact of lower-body strength and power asymmetry on sprint and change of direction (COD) performance receives little attention. Therefore, this study aimed to establish the relationship between lower limb power, sprint, and change of direction (COD) performance. In addition, the relationship between lower limb power asymmetry and the above mentioned running tests was determined. Material and Methods: Twenty-four male soccer players from First Polish League (age = 24.8 ±8.2 years, body mass = 77.4 ±16.9kg, body height=179.5 ±14.5cm, soccer training experience = 10 ± 1.5years) took part in …