Medicine and Health Sciences Commons^™

Clinical Use Of Mean Nocturnal Baseline Impedance And Post-Reflux Swallow-Induced Peristaltic Wave Index For The Diagnosis Of Gastro-Esophageal Reflux Disease, Pierfrancesco Visaggi, Lucia Mariani, Federica Baiano Svizzero, Luca Tarducci, Andrea Sostilio, Marzio Frazzoni, Salvatore Tolone, Roberto Penagini, Leonardo Frazzoni, Linda Ceccarelli, Vincenzo Savarino, Massimo Bellini, Prakash C Gyawali, Edoardo V Savarino, Nicola De Bortoli

2020-Current year OA Pubs

The clinical diagnosis of gastro-esophageal reflux disease (GERD) is based on the presence of typical esophageal troublesome symptoms. In clinical practice, heartburn relief following a proton pump inhibitor (PPI) trial or endoscopy can confirm a diagnosis of GERD. In cases of diagnostic uncertainty or before anti-reflux interventions, combined impedance-pH monitoring (MII-pH) provides a comprehensive assessment of both physical and chemical properties of the refluxate, allowing to achieve a conclusive diagnosis of GERD. Recently, the Lyon Consensus proposed the use of mean nocturnal baseline impedance (MNBI) and post-reflux swallow-induced peristaltic wave index (PSPW-I) as novel MII-pH metrics to support the diagnosis …

Anxiolytics For Bronchodilation: Refinements To Gaba, Ajay P Nayak, Steven S An

Department of Medicine Faculty Papers

No abstract provided.

Tdcs Induced Gaba Change Is Associated With The Simulated Electric Field In M1, An Effect Mediated By Grey Matter Volume In The Mrs Voxel, Tulika Nandi, Oula Puonti, William T. Clarke, Caroline Nettekoven, Helen C. Barron, James Kolasinski, Taylor Hanayik, Emily L. Hinson, Adam Berrington, Anderson M. Winkler

School of Medicine Publications

Background and objective

Transcranial direct current stimulation (tDCS) has wide ranging applications in neuro-behavioural and physiological research, and in neurological rehabilitation. However, it is currently limited by substantial inter-subject variability in responses, which may be explained, at least in part, by anatomical differences that lead to variability in the electric field (E-field) induced in the cortex. Here, we tested whether the variability in the E-field in the stimulated cortex during anodal tDCS, estimated using computational simulations, explains the variability in tDCS induced changes in GABA, a neurophysiological marker of stimulation effect.

Methods

Data from five previously conducted MRS …

The Gendered Profession: Resuscitating The Value Of The Male Nurse In The Pre-Health Undergraduate Eye, Madolyn Dolce, Anne Koenig Phd

Creative Collaborations: Annual Showcase of Undergraduate Research

Background

Gender Gap: Women represent 88.5% of registered nurses in the U.S. (U.S. Bureau of Labor Statistics, 2021)

• Nurses have been devalued and degraded socially, professionally, and economically, especially with COVID-19 (National Nurses United, 2020).
• Reflects gender roles and societal perceptions of women as “lesser” and thus nursing is avoided by men.

Role/Goal Congruence Theory

• According to role congruence theory, social roles direct individuals on their life path, most notably in their career choices (Diekman & Eagly, 2008).
• Goal congruence theory suggests men and women tend to chase careers that align with agentic or communal goals, respectively (Diekman et al., …

The Covid-19 Crisis In The Cali-Baja Region, Allyson Teague, David A. Shirk Phd

Creative Collaborations: Annual Showcase of Undergraduate Research

The central research question posed was “what have been the economic, public health, and social impacts of the Covid-19 crisis in the Cali- Baja region?”

The Covid-19 pandemic has impacted several communities around the world, and economic and health consequences have also exacerbated existing issues. In Cali Baja, the nature of having a population dependent upon cross-border travel and collaboration has resulted in unique ramifications for businesses, governments, and individuals. Understanding the ways in which this pandemic has, and continues to, spread as well as how it disproportionately affects specific populations provides needed insight for governmental responses for the inevitability …

Intra-Aortic Balloon Pump May Attenuate Adverse Hemodynamic Effects Of Negative Intrathoracic Pressure In Cardiogenic Shock, Faris Araj

The VAD Journal

High negative intrathoracic pressure (NIP), as occurs during obstructive sleep apnea or hiccups, results in adverse hemodynamic consequences, specifically a decrease in left ventricle (LV) performance. These untoward effects can potentially be catastrophic in the case of an already compromised LV in cardiogenic shock. The interplay of intra-aortic balloon pump counter pulsation during abrupt high NIP in cardiogenic shock is described.

The Effects Of Cyp1a2 And Adora2a Genotypes Association With Acute Caffeine Intake On Physiological Effects And Performance: A Systematic Review, Rabia Rümeysa Kocatürk, İlke Karagöz, Ebru Yanik, Öznur Özge Özcan, Türker Tekin Ergüzel, Mesut Karahan, Nevzat Tarhan

Baltic Journal of Health and Physical Activity

Introduction: This systematic review aims to examine the effects of the CYP1A2 −163C>A and ADORA2A 1976T>C polymorphism on physiological effects and performance relative to caffeine consumption. Material and Methods: In this study, electronic databases including PubMed, Web of Science Core Collection, Korean Journal Database, Russian Science Citation Index, SciELO Citation Index, Scopus, ScienceDirect, ProQuest Dissertations & Thesis Global and EBSCO were searched. Results: The results highlight that individuals with the TT or CT/CC genotype can have differences in caffeine consumption, and C carriers may have increases in the maximum oxygen uptake (VO₂max). The AA or AC/CC …

Medical School Watercooler Newsletter - September 30, 2022, Lindsey Lyle

Watercooler Newsletter

This is the September 30, 2022 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents include:

• Williams presents at national Medical Summit on Firearm Injury Prevention
• Faculty members needed for academic coaching
• USA Comprehensive Sickle Cell Center named for Johnson Haynes, Jr., M.D.
• USA researchers uncover novel insights into mitochondrial diseases
• Register now: Paddle the Escatawpa River CME Conference

External Apical Root Resorption Of Maxillary Incisors Following Orthodontic Treatment In Patients With Short Root Anomaly: A Cbct Study, Eric Le, Jonas Bianchi, Heesoo Oh

Orthodontics and Endodontics Theses

Introduction: The purpose of this study was to evaluate the amount of external apical root resorption (EARR) secondary to orthodontic treatment in patients with Short Root Anomaly (SRA) using Cone Beam Computed Tomography (CBCT) at the University of the Pacific Orthodontic Clinic. Material and Methods: In this retrospective study, CBCTs of forty-eight SRA patients who underwent orthodontic treatment were selected from the graduate orthodontic clinic. CBCTs before and after treatment were analyzed to measure root length changes on the upper central and lateral incisors. Results: Differences between the two methods of assessing SRA severity occurred between categorizing mild and moderate …

Three-Dimensional Analysis Of Skeletal Changes And Stability In Fixed Orthodontics Vs. Invisalign Therapy In Patients Undergoing Surgery First Approach, Mojan Mirnia, Hyeon-Shik Hwang, Jonas Bianchi

Orthodontics and Endodontics Theses

Introduction: The objective of this retrospective longitudinal study was to assess and compare the surgical changes and stability of the maxilla, mandible, and mandibular condyle, in patients who have undergone surgery first approach (SFA) followed by conventional braces or Invisalign (Inv) treatment. Methods: Thirty patients had a cone beam computed tomography (CBCT) exam taken at three timepoints: T1 (presurgery), T2 (immediately after surgery), and T3 at the completion of orthodontics treatment. After the cranial base registration, twenty-seven landmarks were located on each time point using axial, sagittal, and coronal cross-sectional views in the ITK-SNAP software. In addition, seventeen skeletal angular …

Efficacy Of Caries Detection And Characterization Using Near-Infrared Imaging Technology In The Itero Element 5d Intraoral Scanner In Comparison To Clinical-Reference Standard Bitewing Radiographs In A Pediatric Population, Kyle Cuenin, James Chen

Orthodontics and Endodontics Theses

Introduction: Near infrared imaging (NIRI) uses non-ionizing radiation in the near-infrared spectrum to differentially scatter light off tooth surfaces. This generates images that allow for interproximal caries detection, which have been proposed as an alternative to radiographic detection. The new iTero Element 5D intraoral scanner (Align Technology) has integrated NIRI capture and viewing technology but has not been specifically studied in a pediatric population. Therefore, the goal of this study was to assess clinicians’ abilities to detect and characterize caries in pediatric patients using this instrument. Methods: Bitewing (BW) radiographs and a NIRIenabled intraoral scan were captured on 17 pediatric …

Searching For Association Of Gsk3Β Rs13314595, Msx1 Rs3821949, Tgfβ3 Rs3917201, And Bmp4 Rs17563 With Non-Syndromic Cleft Lip And Palate, Gabrielle Wainwright, Marie M. Tolarová Md, Phd, Drsc, Mirek Tolar

Orthodontics and Endodontics Theses

Introduction: Non-syndromic cleft lip with or without cleft palate (NCL±P) is characterized by a multifactorial etiology with both genetic and environmental factors playing a role in its embryonic development. Recent genetic studies have identified susceptibility loci and genetic variations in several genes that were associated with the risk of developing NCL±P. The purpose of this study was to investigate the association of MSX1, BMP4, TGFβ3, and GSK3β gene variants with NCL±P in a casecontrol data set from Karaikal, India. Methods: The case sample consisted of 331 individuals who were diagnosed with CL (bi/unilateral cleft lip), CLP (bi/unilateral cleft lip and …

In Search Of A Value Proposition For Covid-19 Testing In The Work Environment: A Social Marketing Analysis, Claudia Parvanta, Alberto J. Caban-Martinez, Naciely Cabral, Cynthia K. Ball, Kevin G. Moore, Adrienne Eastlake, Jeffrey L. Levin, Dalia E. Nessim, Matthew S. Thiese, Paul A. Schulte

School of Medicine Faculty Publications and Presentations

Background: This study examined employer experience with SARS-CoV-2 (COVID-19) asymptomatic testing through a social marketing lens. Social marketing uses commercial marketing principles to achieve socially beneficial ends including improved health and safety behavior. Method: Twenty employers across 11 occupational sectors were interviewed about implementation of COVID-19 testing from January through April 2021. Recorded transcripts were coded and analyzed using marketing's "Four P's": "product," "price," "place," "promotion." Results: COVID-19 tests (product) were uncomfortable, were easily confused, and didn't solve problems articulated by employers. Testing was not widely available or didn't line up with shifts or locations (place). The perceived price, which …

2022-09-30_Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

Contains the tables Statewide Hospital Capacity Report for COVID-19, COVID-19 Metrics, Statewide Hospital Available PPE Tracking for COVID-19, as well as the tables PPE Days On Hand and Patient Census.

The Outcome And Stability Of Anterior Open Bite Treatment With Clear Aligners In Adults, Heeyeon Suh, Kimberly Mahood, Heesoo Oh

Orthodontics and Endodontics Theses

Objectives: This study aimed to examine the outcome and stability of the anterior open bite treatment with clear aligners. Methods: Fifty-two adult anterior open bite patients who underwent nonextraction clear aligner treatment were enrolled. All cases were retained with upper and lower fixed and vacuum-formed retainers. Eleven cephalometric measurements at pretreatment (T1), end-of-active-treatment (T2), and at least 1-year post-treatment (T3) were evaluated. The changes during the treatment and retention period were calculated. Results: Mean end-of-treatment (T2) overbite was 1.1 ± 0.7 mm. The mean change in overbite during treatment was 3.3 ± 1.5 mm. Mean retention (T3) overbite was 1.3 …

Assessment Of Skeletal Changes And Mandibular Plane In Growing Patients Treated With Miniscrew Assisted (Marpe) And Conventional Rapid Palatal Expansion Using Cbct Images, Daniel Voorhees, Jonas Bianchi, Heesoo Oh

Orthodontics and Endodontics Theses

Background: Maxillary expansion has long been used in children and adolescents for transverse discrepancies and dental crowding. With age, the mid-palatal suture becomes increasingly mature, requiring heavy, rapid force in order to achieve skeletal expansion. As an individual grows into adulthood, it has been demonstrated that a skeletally anchored expander can be used in order to achieve successful sutural separation. The side effects between these two types of expanders, including dental tipping with relative extrusion of buccal segments and clockwise mandibular rotation, have been demonstrated to have differences in their degrees of severity. However, most of the studies have evaluated …

Dampak Pandemi Covid-19 Terhadap Mahasiswa Kedokteran, Amanda P. Utari

Jurnal Penyakit Dalam Indonesia

No abstract provided.

The Assossiation Between Stress During The Covid-19 Pandemic And The Incidence Of Dyspepsia Syndrome In The First Year Medical Students, Wahida Rahmi, Yulistini Yulistini, Arina Widya Murni

Jurnal Penyakit Dalam Indonesia

Introduction. Dyspepsia syndrome is a collection of symptoms in the upper digestive tract associated with dysregulation of the hypothalamus-hypophysis axis that is triggered by stress. One of the problems faced in the world today is the COVID-19 pandemic which can be a new stressor, especially for students with many changes in the learning process. This study aimed to examine the relationship between stress during the COVID-19 pandemic and the incidence of dyspepsia syndrome.Methods. An analytic obsevasional with cross-sectional design was conducted in April-June 2021 at the Faculty of Medicine, Andalas University. The subjects of this study were the first batch …

Lactate/Albumin Ratio As A Predictor Of Mortality In Patients With Sepsis And Septic Shock: A Meta-Analysis Study, Fahri Ahmad Baihaqi, Dinda Olinda Delarosa, Rezki Ramadhan

Jurnal Penyakit Dalam Indonesia

Introduction. The lactate/albumin ratio is an inflammatory biomarker that has been widely used and suggested as a predictor of mortality in patients with sepsis and septic shock. However, the results are inconsistent. This meta-analysis aimed to evaluate the prognostic value of lactate/albumin ratio as a predictor of mortality in patients with sepsis and septic shock.Methods. The study protocol was registered with PROSPERO (CRD42021286242). A literature search was performed using PubMed, Ovid EMBASE, Ovid MEDLINE, SCOPUS, and Web of Sciences to find all studies evaluating the association between lactate/albumin ratio and mortality in patients with sepsis and septic shock. Meta-analysis was …

Effectivity Of Acupuncture Therapy In Reduction Of Pain Intensity In Cancer Pain, Hanna Lianti Affadhia, Rahmat Cahyanur, Sri Wahdini, Andhika Rachman

Jurnal Penyakit Dalam Indonesia

Pain is one of the most common complaints and interferes with the quality of life of cancer patients. Several studies recommend multimodal interventions that combine pharmacological and non-pharmacological therapies. Acupuncture therapy is one of the non-pharmacological treatment options that could be considered. This evidence-based case report aimed to examine the effectiveness of acupuncture therapy in reducing pain intensity in patients with cancer pain. Literature searching was performed on three databases (PubMed, Scopus, and Embase). The keywords used are cancer pain, malignant pain, acupuncture, acupuncture therapy, pain intensity, pain assessment, pain scale. The critical review was carried out using guidelines from …

Risk Factors Analysis For Gastroesophageal Reflux Disease In Covid-19 Pandemic Era On Resident Physicians Faculty Of Medicine Brawijaya University, Pandu Tridana Sakti, Syifa Mustika

Jurnal Penyakit Dalam Indonesia

Introduction. Resident physicians have a high risk of GERD due to excessive fatigue especially during a COVID-19 pandemic. However, research on resident physicians risk factors for the incidence of GERD in the COVID-19 pandemic era has never been conducted. This study aimed to analyze the risk factors for GERD in the era of the COVID-19 pandemic on resident physicians.

Methods. This study used an analytic observational design with a cross sectional approach. Subjects were resident physicians in clinical and pre-clinical stage at the Faculty of Medicine Brawijaya University which were selected using random sampling method. Questionnaires were given …

Kasabach-Merritt Syndrome In Liver Hemangioma: A Case Report, Michelle Frastica, Rudi Putranto, Chyntia Olivia Maurine Jasirwan, Kresna Adhiatma

Jurnal Penyakit Dalam Indonesia

Hemangioma is the most common congenital benign liver tumor. It affects mostly female, with the incidence of 0.4- 20%. Giant liver hemangioma induce the Kasabach Merritt syndome, a life threathening coagulation disorder which occur due to consumptive coagulopathy: trombocyte sequestration and agregation inside the hemangioma. The mortality rate is around 60%, with the most common cause is multiorgan complication which may end up with sepsis. The core management is hemangioma decompression by surgical measure. However, this often considered as a very risky procedure leading to massive bleeding. In most cases, conservative treatment is the preferred option. It is important to …

Prevalence Of Geriatric Syndromes In Elderly Undergoing Chemotherapy, Aulia Rizka, Helda Helda, Findy Prasetyawaty, Arcita Hanjani

Jurnal Penyakit Dalam Indonesia

Introduction. Geriatric syndromes is associated with poor survival, poor quality of life and increased chemotoxicity risk in elderly receiving chemotherapy. Geriatric syndromes is currently not routinely evaluated in pre-chemotherapy clinical setting. This study aimed to identify the prevalence of some geriatric syndromes in elderly patients undergoing chemotherapy.Methods. This study is part of primary study investigating geriatric syndromes in elderly with cancer. A descriptive cross sectional study during March 2020 – March 2021 was conducted to elderly patients before chemotherapy administration in Cipto Mangunkusumo Hospital, a national referral hospital in Jakarta. Patients were recruited consecutively. Patients underwent Comprehensive Geriatric Assesment (CGA), …

A Paraventricular Thalamo-Accumbal Circuit Necessary For Behavioral Inhibition Is Dysfunctional During Opioid Use And Dependence, Kelsey M. Vollmer

MUSC Theses and Dissertations

Suppression of dangerous or inappropriate reward-motivated behaviors is critical for survival, whereas therapeutic or recreational opioid use can unleash detrimental behaviors and opioid use disorder (OUD). Nevertheless, the neuronal systems that suppress maladaptive motivated behaviors remain unclear, and whether opioids disengage those systems is unknown. Here, we investigate the posterior paraventricular thalamus (pPVT) as a behavioral mediator due to its strong connectivity with brain structures important for reward processing, such as the nucleus accumbens (NAc). We and others have found pPVT-NAc neuronal activity is inhibited during reward seeking, but activated when such behaviors would be inappropriate, such as during stress …

Class Iii Correction Using Clear Aligner Therapy In Adult Patients, Kyra Lee, Kimberly Mahood, Heesoo Oh

Orthodontics and Endodontics Theses

Introduction: This study was designed to analyze the cephalometric changes in adult Class III malocclusion treated with clear aligner therapy. Methods: In this retrospective study, thirty-six Class III adult patients treated with clear aligner therapy in private practice and a graduate orthodontic clinic were included in this study. Inclusion criteria included patients aged 18 years and older, Class III molar relationship that is end-on or greater, at least one anterior tooth that is in crossbite or incisors in an edge-to-edge bite, and complete records (initial and final lateral cephalograms) that are clear and traceable. Twenty-two cephalometric measurements were measured and …

Early Prediction Of The Need For Orthognathic Surgery In Patients With Cleft Lip And Palate Using Skeletal And Soft Tissue Cephalometric Landmarks, Bianca Amy Lau, James Chen, Marie M. Tolarová Md, Phd, Drsc

Orthodontics and Endodontics Theses

No abstract provided.

Stroke Genetics Informs Drug Discovery And Risk Prediction Across Ancestries, Aniket Mishra, Carlos Cruchaga, Et Al.

2020-Current year OA Pubs

Previous genome-wide association studies (GWASs) of stroke - the second leading cause of death worldwide - were conducted predominantly in populations of European ancestry

Analysis Of Prolanis Policy Implementation During The Covid-19 Pandemic In 2021, D.Fitria Sari Firdaus, Mardiati Nadjib

Journal of Indonesian Health Policy and Administration

Data from Basic Health Research (Riskesdas) in 2018 shows that Diabetes and Hypertension dominate chronic diseases. The Director of BPJS Kesehatan has issued Circular No. 14 of 2020 concerning health services for national health insurance participants during the COVID-19 prevention period, especially Prolanis. The policy contains an appeal to postpone the provision of services in the form of mass gathering activities such as Prolanis Gymnastics, Club Education, and and other activities. Hence, this research is needed to describe the implementation of Prolanis policies during the COVID-19 Pandemic. The study used a descriptive research design with qualitative methods and George C. …

Description Study Of Pandeglang Community Knowledge On Natural Disasters And Government Policies Related To Natural Disaster Preparedness In 2022, Novi Anggraini Ginting, Wiku Bakti Bawono Adisasmito

Journal of Indonesian Health Policy and Administration

Pandeglang Regency, which is a disaster-prone area, requires people who have sufficient knowledge to create community preparedness in dealing with disasters and can assist in the disaster mitigation process. This study aims to find out how the community's knowledge and community preparedness related to natural disasters and what efforts have been made by the government to improve the readiness of the people of Pandeglang Regency. This research method is descriptive and quantitative with 451 respondents. The results of the study showed that the people of Pandeglang Regency still did not know correctly the different types of threats or types of …

Outcome Result Of Acute Myeloid Leukemia Undergoing Treatment In Semi-Isolation Chemotherapy Ward, Cosphiadi Irawan, Ricci Steven, Ralph Girson Gunarsa, Jeffry Bela Tenggara

Jurnal Penyakit Dalam Indonesia

Introduction. Standard positive pressure isolation room is not yet widely available in Indonesia. In several private hospitals, current best practice is admitting patients to semi-isolation room with additional protective measures. Despite the limitation, this practice is considered safe and might benefit Acute Myeloid Leukemia (AML) patients. This study aimed to analyze the leukemic profile and survival in AML patients admitted to semi-isolation room. Methods. A retrospective cohort study was conducted using secondary data from medical record of AML patients diagnosed in Mochtar Riady Comprehensive Cancer Center between 2018 – 2020. Patients were divided into semi-isolation room group and not admitted …