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2022

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Full-Text Articles in Medicine and Health Sciences

Neurology Resident Eeg Training In Europe, Fábio A Nascimento, Jay R Gavvala, Hatice Tankisi, Sándor Beniczky Jan 2022

Neurology Resident Eeg Training In Europe, Fábio A Nascimento, Jay R Gavvala, Hatice Tankisi, Sándor Beniczky

2020-Current year OA Pubs

OBJECTIVE: To detail current European EEG education practices and compare European and U.S. EEG teaching systems.

METHODS: A 19-question online survey focused on EEG clinical practices and residency training was emailed to all 47 European Academy of Neurology Societies.

RESULTS: Thirty-two (68 %) out of the 47 Societies completed the survey. In half of countries, general neurologists are either among the providers or the only providers who typically read EEGs. The number of weeks devoted to EEG learning required to graduate ranged from none to 26, and it was expected to be continuous in one country. In most countries (n …


Sexual Minority Stress And Mental Health: An Investigation Of Rural-Urban Differences In Social Support, Justin T. Miller Jan 2022

Sexual Minority Stress And Mental Health: An Investigation Of Rural-Urban Differences In Social Support, Justin T. Miller

College of Graduate Studies: Theses & Dissertations

As mental health disparities and discrimination facing the LGB (sexual minority) community continues to come into public focus, researchers and clinicians are moving toward identifying LGB-specific mental health interventions to support well-being efforts within this population. Furthermore, much of the current literature on sexual minority mental health is focused on predominantly urban samples failing to consider the sociocultural impacts of living in low resourced and geographically isolated regions of the United States (US). To this end, social support is a promising prevention factor, but few studies to date examine its influence on different minority stress models. As such, the current …


Effects Of Various Golf Bag Loading Strategies On Perceived Exertion And Vertical Jump Performance, Austen Arnold Jan 2022

Effects Of Various Golf Bag Loading Strategies On Perceived Exertion And Vertical Jump Performance, Austen Arnold

College of Graduate Studies: Theses & Dissertations

INTRODUCTION: The sport of golf is increasing in popularity among both novice and skilled players alike. A round of golf necessitates players to cope with a range of physically demanding movement patterns. At the collegiate level, golfers must transport their clubs by loading them onto the body. Previous literature has yet to determine how different golf bag carrying positions influence periodic, unloaded jump performance and perceived exertion of the load carrying task. PURPOSE: The purpose of this study is to investigate how different golf bag load carriage methods may influence vertical jump performance and perceived exertion. METHODS: Five golf bag …


Bridging The Gaps: Exploring Factors Associated With Goal Achievement Within An Accountable Care Organization Care Coordination Program, Jessica L. Polk Jan 2022

Bridging The Gaps: Exploring Factors Associated With Goal Achievement Within An Accountable Care Organization Care Coordination Program, Jessica L. Polk

College of Graduate Studies: Theses & Dissertations

Background: Healthcare cost in the U.S. has been increasing at an unsustainable rate due to the growing population diagnosed with multiple chronic conditions and a fragmented healthcare system. The high-risk patient population includes persons who over utilize the healthcare system with frequent avoidable hospitalizations, emergency room visits, and exacerbations of their chronic conditions. This high-risk population makes up five percent of the U.S. but accounts for over fifty percent of all healthcare spending. Care coordination models have emerged to focus proactive health interventions for the highest-risk patient populations to reduce overutilization and empower patients to improve long-term health. Evidence has …


Modelling Muscle Activation Using Emg Signal, Mercy U. Okonna Jan 2022

Modelling Muscle Activation Using Emg Signal, Mercy U. Okonna

College of Graduate Studies: Theses & Dissertations

(EMG) is a method for measuring muscle activity by an electrical signal, and is useful in studying motor control, postural control, and in physical therapy. A current research topic is creating an algorithm that can use the EMG signal to reliably classify a muscle as active or inactive. This thesis presents a classification algorithm for leg muscles with a single activation spike while walking. Time is rescaled into steps, which are identified using data from cameras measuring joint angles while walking. The algorithm is based on moving averages and a convex combination of mean signal strength in active and inactive …


A Proportionality-Based Framework For Government Regulation Of Digital Tracing Apps In Times Of Emergency, Sharon Bassan Jan 2022

A Proportionality-Based Framework For Government Regulation Of Digital Tracing Apps In Times Of Emergency, Sharon Bassan

Dickinson Law Review (2017-Present)

Times of emergency present an inherent conflict between the public interest and the preservation of individual rights. Such times require granting emergency powers to the government on behalf of the public interest and relaxing safeguards against government actions that infringe rights. The lack of theoretical framework to assess governmental decisions in times of emergency leads to a polarized and politicized discourse about potential policies, and often, to public distrust and lack of compliance.

Such a discourse was evident regarding Digital Tracing Apps (“DTAs”), which are apps installed on cellular phones to alert users that they were exposed to people who …


Primary Care Characteristics And Medication Management Among Patients Receiving Office Based Opioid Treatment With Buprenorphine, Xinxin Du Jan 2022

Primary Care Characteristics And Medication Management Among Patients Receiving Office Based Opioid Treatment With Buprenorphine, Xinxin Du

Yale Medicine Thesis Digital Library

AbstractBackground: Office-based opioid treatment (OBOT) is an evidence-based treatment model for opioid use disorder (OUD) offered by both addiction and general primary care providers (PCPs). Calls exist for more PCPs to offer OBOT. Few studies have been conducted on the primary care characteristics of OBOT patients. Objective: To characterize medical conditions, medications, and treatment outcomes among patients receiving office-based opioid treatment (OBOT) with buprenorphine for OUD, and to describe differences among patients by age and by time in care. Methods: This study is a retrospective review of medical records on or before 4/29/2019 at an outpatient primary care clinic within …


Environmental Racism In Baltimore: A Geographical Study Into The Connections Between Environmental Toxins And Public Health, Genevieve Block Jan 2022

Environmental Racism In Baltimore: A Geographical Study Into The Connections Between Environmental Toxins And Public Health, Genevieve Block

Honors Theses

An investigation into the relationship between environmental toxins and environmental racism in Baltimore City, Maryland.


Nurses’ Perceptions Of Their Role Utilizing Eat, Sleep, Console, In The Management Of Neonatal Abstinence Syndrome, Cerys Eldred Jan 2022

Nurses’ Perceptions Of Their Role Utilizing Eat, Sleep, Console, In The Management Of Neonatal Abstinence Syndrome, Cerys Eldred

Honors Theses and Capstones

Background: There is a rising prominence of infants being born and diagnosed with Neonatal Abstinence Syndrome (NAS) in the United States. In recent years, a new non-pharmacological method of managing these infants called Eat, Sleep, Console (ESC) has emerged. While there is mounting evidence demonstrating the positive outcomes for infants treated with this method, there is limited research regarding nurses’ perceptions of this new intervention. This study seeks to understand the nurse’s experience and role during caring for infants with NAS utilizing the ESC method in comparison to the past practices.

Methods: This study used a qualitative descriptive design to …


Neuromotor Changes In Participants With A Concussion History Can Be Detected With A Custom Smartphone App, Christopher K. Rhea, Masahiro Yamada, Nikita A. Kuznetsov, Jason T. Jakiela, Chanel T. Lojacono, Scott E. Ross, F. J. Haran, Jason M. Bailie, W. Geoffrey Wright Jan 2022

Neuromotor Changes In Participants With A Concussion History Can Be Detected With A Custom Smartphone App, Christopher K. Rhea, Masahiro Yamada, Nikita A. Kuznetsov, Jason T. Jakiela, Chanel T. Lojacono, Scott E. Ross, F. J. Haran, Jason M. Bailie, W. Geoffrey Wright

Rehabilitation Sciences Faculty Publications

Neuromotor dysfunction after a concussion is common, but balance tests used to assess neuromotor dysfunction are typically subjective. Current objective balance tests are either cost- or space-prohibitive, or utilize a static balance protocol, which may mask neuromotor dysfunction due to the simplicity of the task. To address this gap, our team developed an Android-based smartphone app (portable and cost-effective) that uses the sensors in the device (objective) to record movement profiles during a stepping-in-place task (dynamic movement). The purpose of this study was to examine the extent to which our custom smartphone app and protocol could discriminate neuromotor behavior between …


Storytelling Of Interprofessional Teamwork, Jessica Lee, Ashley Ronzo, Kendall Dolan, Daniel Bergeron Jan 2022

Storytelling Of Interprofessional Teamwork, Jessica Lee, Ashley Ronzo, Kendall Dolan, Daniel Bergeron

CECE Spring Poster Session 2022

We are an interprofessional team that worked together to discuss and treat a patient suffering from Long COVID-19. At the beginning, we came in with assumptions of other professions and carried our biases into the group. However, as we witnessed these professions interact with our Long COVID-19 patient, Amanda, our views and biases began to change. We were privileged to see how interprofessional teams interact and come together for the betterment of our patient.


Fetal Alcohol Spectrum Disorder Awareness, Stephanie Burns, Danielle Clymer Jan 2022

Fetal Alcohol Spectrum Disorder Awareness, Stephanie Burns, Danielle Clymer

CECE Spring Poster Session 2022

We are an interprofessional team that worked together to educate and bring awareness to FASD. There are a lot of misconceptions regarding this disorder. After learning that there are no medical trainings for physicians regarding diagnosing which results in a lack of therapy, we were eager to bring awareness to this serious matter.


Still Birth Classification: Application Of Relevant Condition At Death (Recode) Classification System In A Tertiary Care Hospital Of Pakistan, Urooj Kashif, Shelina Bhamani, Asma Patel, Zaheena Shamsul Islam Jan 2022

Still Birth Classification: Application Of Relevant Condition At Death (Recode) Classification System In A Tertiary Care Hospital Of Pakistan, Urooj Kashif, Shelina Bhamani, Asma Patel, Zaheena Shamsul Islam

Department of Obstetrics & Gynaecology

Objectives: To determine the cause of stillbirth after application of relevant condition at death (ReCoDe) classification system.
Methods: This was a retrospective cross sectional study of 207 women diagnosed with stillbirth after 24 completed weeks of pregnancy at the Aga Khan University Hospital (AKUH), Karachi between 1st January 2015 and 31st December 2019. The primary objective was to find the cause of stillbirth according to the new classification of relevant condition at death (ReCoDe).
Results: There were a total of 32413 live births and 207 stillbirths during the study period thus stillbirth rate of 6 per 1000 live births. In …


Fear, Faith And Finances: Health Literacy Experiences Of English And Swahili Speaking Women Newly Diagnosed With Breast And Cervical Cancer, Diana Kassaman, Tayreez Mushani, Peterson Kiraithe, Sharon Brownie, Margaret Barton-Burk Jan 2022

Fear, Faith And Finances: Health Literacy Experiences Of English And Swahili Speaking Women Newly Diagnosed With Breast And Cervical Cancer, Diana Kassaman, Tayreez Mushani, Peterson Kiraithe, Sharon Brownie, Margaret Barton-Burk

School of Nursing & Midwifery, East Africa

Breast and cervical cancer are among the leading causes of cancer-related deaths globally. In Kenya, delayed presentation and diagnosis contribute to breast and cervical cancer mortality. The Kenyan government acknowledges the cancer burden with estimated 39,000 new cases diagnosed and 27,000 deaths per annum. Mortality can be reduced if cancer is diagnosed early and with appropriate treatment. Health Literacy (HL) about cancer screening, diagnosis and treatment is important in reducing mortality, but there is little understanding about HL levels, experiences of patients diagnosed with breast and cervical cancer and the contexts in which they make decisions. In this study, health …


Exploring Agricultural Worker Self-Efficacy During A Covid-19 Delta Variant Surge And Adverse Environmental Conditions, Hannah Lascano Jan 2022

Exploring Agricultural Worker Self-Efficacy During A Covid-19 Delta Variant Surge And Adverse Environmental Conditions, Hannah Lascano

All Master's Theses

Yakima County is a rural county with an urban core located in central Washington State. With over 60% of its workforce dedicated to agriculture, food production, and other essential industries, the impact of the COVID-19 pandemic has been particularly compounded in Yakima County populations. Factors such as low decision-making power, limited ability to social distance, and occupational limitations such as fear of job loss, non-compliance with immigration regulations, and lack of representation have yet to be explored during the COVID-19 Delta variant (Delta) surge in conjunction with environmental conditions. This study utilized a novel, online survey of Yakima County residents, …


Social Media Addiction And Self-Esteem Among Students Of Degree Colleges Of Udupi Taluk, Karnataka, India, Sriparna Sarkar, Linu George, Latha T Jan 2022

Social Media Addiction And Self-Esteem Among Students Of Degree Colleges Of Udupi Taluk, Karnataka, India, Sriparna Sarkar, Linu George, Latha T

Manipal Journal of Nursing and Health Sciences

Abstract

As a quintessential part of our routine life, social media users are projecting the success or their achievements to potentially large virtual onlookers to obtain visible recognitions through positive comments from other social media users.

Objective: The objective was to determine the relationship between social media addiction and self-esteem among college students.

Methods: A correlative survey was conducted among 658-degree college students from selected colleges. Prior to the study, administrative permissions were obtained from the colleges which were selected by using simple random sampling technique. The Social Media Addiction scale, Rosenberg’s self-esteem scale, and Background proforma were used for …


Professional Values Among Bsc Nursing Students And Their Perception Of The Status Of Nursing As A Profession, Joselin Mariet Jan 2022

Professional Values Among Bsc Nursing Students And Their Perception Of The Status Of Nursing As A Profession, Joselin Mariet

Manipal Journal of Nursing and Health Sciences

ABSTRACT

Professional values are the values reflected in our relationship with clients, colleagues and the significant others. The ‘Code of Ethics’ for nurses provide directions for relationship of nurses to clients, community and the profession and it delineates the fundamental values of professional nursing. Objectives: To describe and correlate the professional values of B Sc Nursing students and their perception on status of nursing as a profession; to compare the professional values and perceptions of I, II, III and IV year students; to find out the relationship of professional value and perception scores of students with their socio-economic status. …


An Extreme Preterm Infant With Multiple Complications: A Case Study, Yashoda Sathish Jan 2022

An Extreme Preterm Infant With Multiple Complications: A Case Study, Yashoda Sathish

Manipal Journal of Nursing and Health Sciences

Extreme preterm birth is the most critical risk factor, which leads to adverse effects on medical and developmental outcomes. We report a case of an extremely preterm infant admitted to NICU and had a prolonged period of non-invasive ventilation. The neonate had hepatosplenomegaly and antibiotic, antifungal, and antiviral treatment. She was recovered and shown significant improvement in her health status and growth and development were assessed until five years of corrected age.


Equine-Assisted Therapy And Learning Interventions With Youth: A Meta-Analysis And Quasi-Experimental Study., Sarah Lovins Jan 2022

Equine-Assisted Therapy And Learning Interventions With Youth: A Meta-Analysis And Quasi-Experimental Study., Sarah Lovins

Graduate Theses/Dissertations

Equine-assisted psychotherapy interventions have become increasingly used and tested as an alternative or complementary approach with youth. This project presents two studies. The first study consists of an overview of existing reviews and a meta-analysis of controlled and comparison studies on the effectiveness of equine interventions with youth. A comprehensive search and selection procedure produced 3,525 records, from which 56 quantitative studies were identified, and ultimately 16 controlled or comparison studies were selected for inclusion in the meta-analysis. Results showed a statistically significant, medium, and homogenous effect size for the overall effectiveness of equine interventions for youth psycho-social outcomes ( …


Interoception Toolkit: A Resource For Occupational Therapy Practitioners To Use With Children And Their Families, Heidi Lynn Janssen Jan 2022

Interoception Toolkit: A Resource For Occupational Therapy Practitioners To Use With Children And Their Families, Heidi Lynn Janssen

Occupational Therapy Capstones

Purpose: Interoception refers to one’s ability to sense the internal condition of the body, including sensory messages from body parts and internal organs (Craig, 2002). In the past 30 years, scientists and researchers have discovered a powerful connection between interoceptive appraisal skills and self-regulation, emotional identification, emotional regulation, social skills, and nearly every task in daily life (Mahler, 2017). The purpose of this project is to provide practitioners with an educational platform that describes the sensorimotor skill of interoception applied throughout the occupational therapy process.

Methods: The development of this product was initiated with a thorough review of literature to …


Addressing The Recreation And Social Participation Gap In Children With Disabilities: Program Development Of A Recreational Summer Camp, Benjamin Isaac Germolus Jan 2022

Addressing The Recreation And Social Participation Gap In Children With Disabilities: Program Development Of A Recreational Summer Camp, Benjamin Isaac Germolus

Occupational Therapy Capstones

Recreation, social participation, and leisure are important occupations of children, however, children with disabilities participate in them less frequently and more often with parents when compared to their typically developing (TD) peers (Lin, 2020; Schreuer et al., 2014; Solish et al., 2010). Therapeutic summer camps have been shown to reduce these disparities in participation while achieving positive functional gains (Flynn et al., 2019; Guest et al., 2017; Kaboski et al., 2015; Petersen et al., 2020; Sakzewski et al., 2015; Sterman et al., 2016; Walker et al., 2010; Yang et al., 2021). However, few summer camp programs are available for occupational …


Meeting Sensory Needs: A Childcare Provider’S Guide To Support Sensory Strategies In The Daycare Setting, Mckenzie Dye Jan 2022

Meeting Sensory Needs: A Childcare Provider’S Guide To Support Sensory Strategies In The Daycare Setting, Mckenzie Dye

Occupational Therapy Capstones

Meeting Sensory Needs: A childcare provider’s guide to support sensory strategies in the daycare setting.

Purpose: The purpose of this project is to create a supplemental sensory guide to support childcare providers in creating a sensory rich environment. This product incorporated the expertise of occupational therapy to create a sensory guide that outlines a sensory activity bank and environmental modifications.

Background: A high percentage of children in childcare experience sensory related difficulties that hinder their performance in daily activities. Many children in daycare who have sensory processing difficulties are being treated as if they have behavior problems, which can have …


Secondary To Post-Secondary Education Transition: A Guide For Self-Advocacy And Self-Determination, Karleen T. Vonkrosigk Jan 2022

Secondary To Post-Secondary Education Transition: A Guide For Self-Advocacy And Self-Determination, Karleen T. Vonkrosigk

Occupational Therapy Capstones

Introduction: Post-secondary transitions encapsulate the stage of life between high school and adulthood where adolescents transition to college, technical school, work, or other options (Palmon et al., 2017). It is not uncommon for students to lack the skills and strategies needed for self-advocacy and self-determination, which are crucial to success throughout adulthood (Palmon et al., 2017). Upon reviewing current literature, it was identified that supportive transition services begin to diminish after secondary education ends (Kramer, 2015). A product that helps guide and support individuals transitioning to post-secondary education is beneficial and needed.

Methodology: Extensive research was completed through a literature …


Enhancing Occupational Performance Outcomes For Individuals With Orthopedic Injuries That Includes Psychosocial Well-Being Considerations In Occupational Therapy, Tyler Stecher Jan 2022

Enhancing Occupational Performance Outcomes For Individuals With Orthopedic Injuries That Includes Psychosocial Well-Being Considerations In Occupational Therapy, Tyler Stecher

Occupational Therapy Capstones

Approximately one-third of people who sustain any type of acute orthopedic injury experience depression, one-quarter experience post-traumatic stress disorder (PTSD) and up to one-half have anxiety up to 10 years after the initial injury (Breazeale et al., 2021; Muscatelli et al., 2017). These psychosocial factors can have negative impacts on clients’ everyday life and occupations such as participation in social activities, return to work, and limit independence in daily activities (Vincent et al., 2018). Occupational therapists are often responsible for evaluating and providing intervention for individuals with upper extremity orthopedic injuries; more than 85% of certified hand therapists are occupational …


Occupational Therapist’S Role In Addressing The Psychological Impacts Of Pain In Clients With Upper Extremity Conditions, Shivangi Patel Jan 2022

Occupational Therapist’S Role In Addressing The Psychological Impacts Of Pain In Clients With Upper Extremity Conditions, Shivangi Patel

Occupational Therapy Capstones

Background & Purpose: The experience of pain is different for every client (Felman, 2020). There are various ways to feel and describe the pain (Felman, 2020). A maladaptive response to pain has been associated with increased pain and physical limitations in clients with upper extremity pain (Verhiel et al., 2019). Upper extremity impairments can result in the disruption of many activities of daily living and instrumental activities of daily living (American Occupational Therapy Association, 2014). Clients with upper extremity pain often resort to maladaptive coping strategies, such as catastrophic thinking (Verhiel et al., 2019). The most common psychological factors related …


Functional Cognition In Long-Term Care: Implementing Allen’S Cognitive Level Screen, Sarah Janean Schumacher Jan 2022

Functional Cognition In Long-Term Care: Implementing Allen’S Cognitive Level Screen, Sarah Janean Schumacher

Occupational Therapy Capstones

Title: Functional Cognition in Long-Term Care: Implementing Allen’s Cognitive Level Screen

Purpose: It is motivating to many individuals to remain as independent as possible for as long as possible. As we age, there is a shift to balancing needed support while maintaining independence. According to Allen (1991), cognition is the number one factor affecting an individual’s ability to live independently. Within long-term care, specifically assisted living facilities, cognitive screening processes are in place to measure one’s cognition, however, often the tools in place do not measure functional cognition (Stewart, O’Riley, Edelstein, & Gould, 2012). The purpose of this scholarly project …


Formulation Development Of Drug Loaded Cyclodextrin-Based Nanoparticles For Ocular Delivery, Hay Man Saung Hnin Soe Jan 2022

Formulation Development Of Drug Loaded Cyclodextrin-Based Nanoparticles For Ocular Delivery, Hay Man Saung Hnin Soe

Chulalongkorn University Theses and Dissertations (Chula ETD)

The development of topical eye drops for treatment of glaucoma and fungal keratitis is still challenging. Due to low aqueous solubility of drugs and the presence of ocular barriers, it is difficult to achieve effective therapeutic drug levels in targeted ocular tissues. In this present study, cyclodextrin (CD)-based nanoparticles (NPs) and synthetic CD-polymers were introduced to overcome these drawbacks and evaluated for their safety and efficacy. γ-Cyclodextrin (γCD) was able to increase the solubility of intraocular pressure lowering drugs, i.e., irbesartan (IRB) and candesartan cilexetil (CAC). The addition of Soluplus® significantly enhanced the complexation efficiencies of IRB/γCD and CAC/γCD complexes. …


Remdesivir Analog As Sars-Cov-2 Polymerase Inhibitor: Virtual Screening Of A Database Generated By Scaffold Replacement, Amgad Albohy, Mohamed A. Said, Mohamed A. Abdelrahman, Hany Said Jan 2022

Remdesivir Analog As Sars-Cov-2 Polymerase Inhibitor: Virtual Screening Of A Database Generated By Scaffold Replacement, Amgad Albohy, Mohamed A. Said, Mohamed A. Abdelrahman, Hany Said

Pharmacy

By the end of 2019, a novel strain of the corona viral family named SARS-CoV-2 emerged in Wuhan, China and started to spread worldwide causing one of the most dangerous lethal pandemics. Researchers utilized various reported inhibitors and drug databases for virtual screening analysis against this novel strain. Later on, they succeeded to fish and repurpose remdesivir, an antiviral nucleotide analogue that inhibits RNA polymerase of the Ebola virus, as a promising candidate against SARS-CoV-2. In this study, we used the interactions of the co-crystallized metabolite of remdesivir with SARS-CoV-2 RdRp isozyme (PDB 7BV2) to design an analog with potential …


Impacts Of Covid-19 On Global Healthcare Management And Research, Stephanie Autore, Santanu De Jan 2022

Impacts Of Covid-19 On Global Healthcare Management And Research, Stephanie Autore, Santanu De

Biology Faculty Articles

The Coronavirus Infectious Disease 2019 (COVID-19) pandemic has affected most nations at all levels of functioning, individual to governmental. Therefore, it is imperative to evaluate the effects the virus has had on one of the most important socioeconomic global sectors, healthcare. This literature review explores key, recent research and management strategies that have been undertaken in healthcare systems around the world in order to make meaningful attempts at identifying the etiology, diagnosis, and treatment of the disease, and combating the spread of this deadly virus. Healthcare facilities have implemented a variety of changes, all geared towards reducing non-emergency patient visits …


Interventions Addressing Social And Leisure Participation For Adults With Musculoskeletal Chronic Pain, Kady Locke, Emily Ray, Josie Sylte Jan 2022

Interventions Addressing Social And Leisure Participation For Adults With Musculoskeletal Chronic Pain, Kady Locke, Emily Ray, Josie Sylte

Critically Appraised Topics

FOCUS QUESTION:

P - Adults 18-90 years of age

I - Exploration of most effective OT programs and interventions

C - Musculoskeletal chronic pain

O - Improved participation in social and leisure activities

What are the most effective occupational therapy interventions to improve social and leisure participation in adults aged 18 to 90 who experience chronic musculoskeletal pain?