Medicine and Health Sciences Commons^™

Heart Rate Variability And Stress In The Intensive Care Unit Nursing Workplace, Paula Miller Levi

All ETDs from UAB

Intensive care unit (ICU) nurses work in a demanding environment, facing repeated encounters with trauma and ethical issues when caring for patients. Psychological stressors can include death of patients, violent acts by patients or their families, caring for suffering patients, and moral distress from performing futile care. These factors place ICU nurses at increased risk of developing post-traumatic stress disorder (PTSD). Suffering from chronic PTSD symptoms can negatively impact nurses’ psychological and physical health. There are also consequences for patients and hospitals, including increased risk for substandard care, decreased government reimbursements from poor patient satisfaction scores, and retention issues. Few …

Put Me In Coach: The Benefits Of Establishing A Dedicated Cvl Access Team To Improve Patient Safety And Nurse Satisfaction, Mae Selassie, Janie Alberto, Diamond Wright

2021

No abstract provided.

Understanding The Protumorigenic Functions Of St6gal1 In Glioblastoma Stemness And Metabolism, Sajina Gc

All ETDs from UAB

Glioblastoma (GBM) is a rare but deadly cancer with median survival of just 15 months despite of aggressive treatment. Advancement in novel treatment modalities is hindered by its heterogeneous nature, which includes subsets of neural stem cell-like brain tumor initiating cells (BTICs) that are highly tumorigenic and therapy-resistant. bgalactoside a-2,6-sialyltransferase 1 (ST6Gal1) is elevated in most tumors including in normal and neoplastic stem cells. ST6Gal1 imparts oncogenic phenotypes such as invasion, apoptosis evasion, therapy resistance, TIC maintenance among others via sialylation of critical receptors like, Fas, TNFR1, EGFR and more. Yet ST6Gal1 led regulation of BTIC specific cell surface proteins …

Dysregulation Of Biomarkers Of Hemostatic Activation And Inflammatory Processes Are Associated With Adverse Outcomes In Pulmonary Embolism, Iman Darwish, Jawed Fareed, Yevgeniy Brailovsky, Debra Hoppensteadt, Brett Slajus, Emily Bontekoe, Frank De Stefano, Trent Reed, Amir Darki

Division of Cardiology Faculty Papers

Introduction: The pathophysiology of pulmonary embolism (PE) represents complex, multifactorial processes involving blood cells, vascular endothelium, and the activation of inflammatory pathways. Platelet (P), endothelial (E), and leukocyte (L)-selectin molecules may play an important role in PE pathophysiology. We aimed to profile the biomarkers of inflammation, including selectins in PE patients, and compare them to healthy individuals.

Materials and methods: 100 acute PE patients and 50 controls were included in this case control study. ELISA methods were used to quantify levels of selectins, inflammatory, and hemostatic biomarkers.

Results: In PE patients, levels of selectin molecules as compared to controls convey …

The Difference In Fracture Strength Of Translucent Zirconia (5y-Z) Using Different Cements And Surface Treatments, Esra Elamin

All ETDs from UAB

Statement of Problem: With the recent advent of translucent and ultra-translucent zirconia, it is unknown if this type of high-strength ceramic restoration requires adhesive cementation to enhance retention as well as the effect of surface treatment thus its clinical applicability requires further investigation. Purpose: To investigate the difference in fracture strength of translucent zirconia (5Y-Z) using different crown thickness, different cements under different surface treatment conditions. Materials and Methods: The experimental design consisted of five groups of 30 specimens each. Two different cements were utilized under different surface treatment conditions. Copings of (1.0 mm) uniform thickness were milled of 3Y-zirconia …

Racial Differences In The Association Of Insulin Resistance With Risk Of Incident Heart Failure In Participants Of Regards, Nirav Patel

All ETDs from UAB

Background: Insulin resistance is linked to the development of heart failure (HF). However, there is limited understanding of the racial differences in the association of insulin resistance with the risk of incident HF among individuals without diabetes. Objectives: In a US national cohort of Black and White participants, we sought to evaluate: 1) the relationship between insulin resistance with incident HF participants, and 2) whether there are racial differences in the association of insulin resistance with HF. Methods: We examined >16,000 participants without HF and diabetes at baseline from the REGARDS cohort. Cox regression modeling was used to assess the …

Assessing The Impact Of The Covid-19 Pandemic On Metastatic Lung Cancer Time To Treatment Initiation, Health Care Resource Utilization, And Costs In The United States, Teresa M. Zyczynski

All ETDs from UAB

The COVID-19 pandemic has derailed normal operations in the health care delivery systems in the United States (US) and globally, providing prioritized care to patients seeking acute management of the novel coronavirus and its complications. Simultaneously, cancer screening tests have decreased, resulting in decreased rates of cancer diagnoses and referrals to oncologists. The purpose of this study was to assess time to treatment initiation (TTI) with systemic cancer therapy in patients with newly diagnosed metastatic lung cancer, metastatic lung cancer-related and total healthcare resource utilization (HCRU) and costs during the pandemic/post-pandemic period compared with the pre-pandemic period. The retrospective claims …

Longitudinal Assessment Of Hospital Utilization Among Infants With Neonatal Abstinence Syndrome And Mothers With Opioid Use, Florida 1998-2018, Amanda Louise Elmore

Theses and Dissertations

Over the past few decades, maternal opioid use and Neonatal Abstinence Syndrome (NAS) have significantly increased. However, few studies have examined prevalence trends by sociodemographic variables. Therefore, the first aim of my dissertation was to determine the prevalence by year for each outcome for the total sample and by maternal race/ethnicity, education level, and insurance type.

Prenatal opioid exposure (POE) poses neonatal risks including Neonatal Abstinence Syndrome (NAS) and studies suggest the effects may extend through childhood. However, there are critical gaps in literature on the long-term developmental outcomes of opioid-exposed infants by presence of NAS. Therefore, the second aim …

Epidemiological Models, Parameters, And Prediction Of The Covid-19 Outbreak In A Southwest Georgia Hotspot, Daniel F. Linder, William M. Sewell Iii, Jack D. Owens, Jim Franklin, Mark Miller, Casey Newton, Priyank Shah

Journal of the Georgia Public Health Association

Background: We investigate epidemiological models, their parameters, and the models’ predictive performance of daily new cases during the first three weeks of the SARS-CoV-2 outbreak in a southwest Georgia hotspot.

Methods: We fit stochastic versions of the classical SIR, a network-based SIR, an SEIR model with two different priors on the latent period rate parameter, and a simple doubling time model to SARS-CoV-2 patients’ date of hospital admission and length of symptoms data from the Phoebe Putney Health System.

Results: The estimated basic reproductive numbers and 95% Bayesian credible intervals for each of the models were: 1.98 (1.63, 2.45) for …

An Analysis Of Georgia Mothers Who Gave Birth In 2015 And 2016 Without Receiving Prenatal Care, Joncel Stephens, Shanta R. Dube, Merrilee Gober

Journal of the Georgia Public Health Association

Background: The present study characterizes the population of women residing in the state of Georgia who did not receive prenatal care before giving birth to a live infant. The association between mother’s place of residence (rural/non-rural) and preterm delivery was also examined.

Methods: This study examined data obtained from the Georgia Department of Public Health which includes data for 7,062 mothers who did not receive prenatal care before giving birth to a live infant in Georgia in the years 2015 and 2016. Data on the resulting births was also studied. Descriptive analyses of the following variables were used …

Can Mini Grant Programs Address Community Health Improvement Plans In Rural Areas? A Local Evaluation, Kelley Ditzel, Cameron Watts

Journal of the Georgia Public Health Association

Background: In the rural community of Hancock County, Georgia, it became apparent in the summer of 2017 that outside help was necessary to address the failing health and education problems plaguing this area. The North Central Health District received Healthcare Georgia Foundation grant leading to the creation of the Hancock Health Improvement Partnership (HHIP) composed of 11 community leaders who developed the Community Health Improvement Plan to positively impact their county.

Methods: This evaluation was conducted to report the efficacy of the mini grant program developed by the HHIP, particularly how grants could best improve organizational capacity, incentivize community collaborations, …

Perception Of Health Care Access In Rural Georgia: Findings From A Community Health Needs Assessment Survey, Elisa M. Childs, Tiffany R. Washington

Journal of the Georgia Public Health Association

Background: Limited access to health care services has been cited as a barrier to care for individuals who live in rural areas, contributing to significant health disparities in this population. While perception of services has been cited as a determinant of utilization of health services, it is unknown how perception of services influences health care access in rural areas. The paucity of studies specific to areas in the United States that are medically underserved, necessitated this study and its quantification of the issues that are relevant to individuals living in rural Georgia.

Methods: This study examined the perception of health …

Elderly Educated Blacks And The Influence Of Exercise Identity, Self-Determination, And Social Determinants Of Health On Physical Activity, George Leonard Shaw Jr., Miles Anthony Irving

Journal of the Georgia Public Health Association

ABSTRACT:

Background: This study examined the influence of socio-economic status (SES), exercise self-definition, and self-determination variables on physical activity participation among African American retirees.

Methods: Both African American men and women, of at least 60 years of age, were surveyed. All participants lived independently. The data collected included demographic, Godin Leisure-Time Physical Activity Questionnaire (LTPA), Exercise Self-Definition Questionnaire (ESD), Behavioral Regulations Exercise Questionnaire-2 (BREQ-2), and Basic Psychological Needs Satisfaction in Exercise Scale (BPNES). The findings and analysis were conducted using data from149 participants.

Results: Only gender was a statistically significant predictor of physical activity participation in the study. Based on …

Role Of Community-Level Health Behaviors And Social Determinants Of Health In Preventable Hospitalizations, Elizabeth Ayangunna, Kingsley A. Kalu, Gulzar H. Shah

Journal of the Georgia Public Health Association

Background

Hospitalizations contribute significantly to the country’s health expenditures. There are factors in addition to clinical care that determines whether a community can prevent hospitalizations from certain medical conditions.

Purpose

The purpose of this paper is to explain the role of community-level health behaviors and social determinants of health (SDoH) in preventable hospitalizations.

Methods

This study used secondary data from the 2021 County Health Rankings for 8 states in HHS Region 4--Georgia, Florida, North Carolina, South Carolina, Alabama, Mississippi, Florida, and Tennessee. Descriptive analyses and multivariate linear regression were computed to examine the association between the dependent variable- preventable hospitalizations …

Impact Of Public Health Nurse Training On Their Perception To Provide Hypertension And Diabetes Care To Patients In Their Communities., Stephen Goggans, Jean O'Connor, Elena A. Wood, Elizabeth Sacksteder Laclair, Kathryn Martin, Paul Wallach

Journal of the Georgia Public Health Association

To evaluate the impact of protocol training by a medical school and public health department on nurses’ perceptions to deliver care to patients with hypertension and diabetes.

Training was delivered using the Georgia Diabetes and Hypertension Nurse protocols for public health nurses. A survey was developed and distributed post training to participants. The training included lectures, workshops, case discussions, simulation, and physical examination practice on standardized patients. Participants were asked about perceptions, both before and after training completion regarding frequency in changing practice and confidence in treating hypertension and diabetes for six items.

Perceived levels of confidence for all questionnaire …

Barriers To Hiv Related Services Among Men Who Have Sex With Men (Msm) In Rural Georgia, Jordan D. Helms, Alvin Tran, Neal Carnes, Eric J. Nehl

Journal of the Georgia Public Health Association

Background: Gay, bisexual, and men who have sex with men (MSM) living in the Southeastern United States are at high risk of contracting HIV, and those in rural communities experience challenges in accessing HIV prevention and treatment.

Methods: Seven health care workers and 17 MSM in rural health care districts participated in semi-structured interviews. A theory-informed thematic analysis approach was used to summarize and compare perspectives between health care workers and MSM participants.

Results: Stigma, insufficient resources, and social structures of rural life emerged as barriers to accessing HIV-related services

Conclusions: Overcoming these barriers are necessary to reduce HIV infection …

Cyberbullying In Middle School Students: An Intervention Using An Educational Mobile Application For Caregivers: A Pilot Study, Gregory C. Claxton

Journal of the Georgia Public Health Association

Cyberbullying among middle school students is a growing problem that is shown to affect psychological development in middle school youth which can result in self-harm and suicide. Evidence suggests more frequent communication between children and their caregivers is a protective factor against cyberbullying. The KnowBullying app is designed to increase caregiver and student communication to prevent bullying. This study examines the effectiveness of the KnowBullying app regarding enhanced caregiver and child communication and cyberbullying experience reduction in middle school students. Five students and nine caregivers were given surveys before and after the caregivers downloaded and used the KnowBullying app. The …

Air Pollutant Levels And Asthma Emergency Room Visits In A Highly Populous Us Urban County During 2018-19, Osaremhen Ikhile, Jingjing Yin, Atin Adhikari

Journal of the Georgia Public Health Association

Objective: Air pollutants are linked to asthma exacerbation. The study purpose was to demonstrate an association between air pollutants levels and asthma emergency room (ER) visit trends in a highly populated US urban county in Georgia during 2018-2019.

Methods: Time series analyses were conducted for the variations in daily numbers of children and adult asthma emergency room visits and changes in daily mean PM_2.5, daily mean PM₁₀ concentrations, daily max 1-hour SO₂ concentrations, daily max 1-hour NO₂ concentrations, daily max 8-hour ozone concentrations, and airborne pollen loads for 2018 to 2019 and potential trends were …

Starting The New Year And Getting Rid Of Type 2 Diabetes?, Sheri R. Colberg

Human Movement Studies & Special Education Faculty Publications

No abstract provided.

Mental Health, Bullying, And Victimization Among Chinese Adolescents, Yang Wen, Xihe Zhu, Justin A. Haegele, Fangliang Yu

Human Movement Studies & Special Education Faculty Publications

The purpose of this study was to examine if adolescents who experience anxiety or depression have higher levels of reported bullying victimization or perpetration than those who do not. Based on the existing research, we hypothesized that those who experienced moderate or severe depression and anxiety would have higher rates of bullying victimization and perpetration when compared to those who experienced mild or no depression. This study used an observational design, and data were collected from a convenience sample of adolescents in a large regional high school in an Eastern province of China. The final sample included 1481 adolescents aged …

Trauma Induced Coagulopathy, Patrick Corey

Rochester General Hospital Grand Rounds

Goals:

• Discuss how traumatic events affect coagulation of patient

• Steps ED doctor can take to prevent and treat coagulopathy

• New technology and how it can help guide trauma care

Ambiguous Genitalia: A Medical, Surgical, Psychiatric And Ethical Concern, Saachi M. Khanna, Anoush Sardesai Sadat, Ranjani Rammohan, Sundeep Payyanur Thotan

Manipal Journal of Medical Sciences

Disorders of Sexual Differentiation or DSDs are congenital anomalies which lead to the abnormal development of the internal and external genitalia. Our main objective in this review was to bring to light the psychiatric side of healthcare for a patient with ambiguous genitalia and DSD and create more awareness of the ethical aspects of the condition. The most important step in the management of DSD is the avoidance of prematurely designating sex or using gendered pronouns, as well as reassuring the family. Treatment is not singular, but a multidisciplinary approach. It involves medical management and surgical correction of the genitalia. …

Realtime Event Detection In Sports Sensor Data With Machine Learning, Mallory Cashman

Honors Theses and Capstones

Machine learning models can be trained to classify time series based sports motion data, without reliance on assumptions about the capabilities of the users or sensors. This can be applied to predict the count of occurrences of an event in a time period. The experiment for this research uses lacrosse data, collected in partnership with SPAITR - a UNH undergraduate startup developing motion tracking devices for lacrosse. Decision Tree and Support Vector Machine (SVM) models are trained and perform with high success rates. These models improve upon previous work in human motion event detection and can be used a reference …

Growing South Dakota (Fall 2021 / Winter 2022), College Of Agriculture, Food And Environmental Sciences

Growing South Dakota (Publication of the College of Agriculture, Food and Environmental Sciences)

[Page] 3 SDSU Launches New Professional Program in Veterinary Medicine
[Page] 7 The 6th Generation
[Page] 9 First-Gen Proud
[Page] 11 Student Success
[Page] 21 Alumni News
[Page] 27 CAFES News and Updates
[Page] 45 Jackrabbits Now and Then: A Current Student and Alumni Q&A

Improving The Process Of Pain Management By Implementing Best Practices In A Nursing Home, Sukhjit Dhillon

Doctoral Projects

Pain is often untreated or undertreated among older adults living in nursing homes. The lack of standardized pain management protocols makes it difficult to address pain in this population. Deficiencies in pain management and documentation were identified in a nursing home and a performance improvement project was implemented with the aim to improve pain management, pain documentation, and staff knowledge of pain management. A pre-and post-intervention study design was used, and data analysis included descriptive statistics and a paired samples t-test. Participants (n=12) included seven registered nurses and five licensed vocational nurses who provide direct care to the residents in …

Educational Intervention With Visual Cues To Increase Compliance With Postoperative Warming, Michael J. Domingo

Doctoral Projects

Millions of operations are performed annually in the United States. However, postoperative hypothermia still affects surgical patients who are not thermoregulated and can occur among them during the postoperative period. Postoperative warming compliance rates across countries and institutions are generally poor (Koh et. al, 2021). Therefore, the focus of the DNP project was to assess how providing education on postoperative warming and providing visual cues to the PACU RNs would increase postoperative warming compliance. The PACU RN participants were provided postoperative warming education with visual cues. Specifically reviewed with the PACU RNs was taking the patient’s temperature, connecting the patient …

Impact Of Mindfulness Practice On Compassion Fatigue In Pediatric Cardiovascular Critical Care Nurses: A Quality Improvement Project, Kendy Luu

Doctoral Projects

Background: A considerable proportion of the extant literature on healthcare has documented compassion fatigue (CF) as a major factor that contributes to poor job performance, satisfaction, and negative patient outcomes (Figley, 2002). CF is well known to negatively impact patient care and outcome, relationships, and job satisfaction among pediatric cardiovascular intensive care (CVICU) nurses. Developing interventions to reduce burnout and CF bear the potential to reduce costs and improve quality care; one particularly promising approach in this regard is the practice of mindfulness-based stress reduction (MBSR). Purpose: This quality improvement project aimed to determine the impact of an abbreviated MBSR …

Dentistry And The Law: Network Leasing Arrangements And Their Effect On Fees, Dan Schulte Jd

The Journal of the Michigan Dental Association

Dentists entering network leasing arrangements often face uncertainty about fees due to the lack of transparent fee schedules. While leasing companies aim to connect dentists with insurers and plans, the absence of clear payment information poses challenges. Dentists may receive varying amounts for the same services, impacting financial predictability. The article emphasizes the importance of understanding contract terms, obtaining fee schedules, and monitoring patient volume to assess the arrangement's overall benefit.

Prevalence Of Mutations In The Pfdhfr, Pfdhps, And Pfmdr1 Genes Of Malarial Parasites Isolated From Symptomatic Patients In Dogondoutchi, Niger, Ibrahima Issa, Mahaman Moustapha Lamine, Veronique Hubert, Amadou Ilagouma, Eric Adehossi, Aboubacar Mahamadou, Neil F. Lobo, Demba Sarr, Lisa M. Shollenberger, Houze Sandrine, Ronan Jambou, Ibrahim Maman Laminou

Biological Sciences Faculty Publications

The effectiveness of artemisinin-based combination therapies (ACTs) depends not only on that of artemisinin but also on that of partner molecules. This study aims to evaluate the prevalence of mutations in the Pfdhfr, Pfdhps, and Pfmdr1 genes from isolates collected during a clinical study. Plasmodium genomic DNA samples extracted from symptomatic malaria patients from Dogondoutchi, Niger, were sequenced by the Sanger method to determine mutations in the Pfdhfr (codons 51, 59, 108, and 164), Pfdhps (codons 436, 437, 540, 581, and 613), and Pfmdr1 (codons 86, 184, 1034, and 1246) genes. One hundred fifty-five (155) pre-treatment samples were …

Qualitative Analysis Of Cancer Care Experiences Among Rural Cancer Survivors And Caregivers, Kendra L. Ratnapradipa, Jordan Ranta, Krishtee Napit, Lady Beverly Luma, Tamara Robinson, Danae Dinkel, Laura Schabloske, Shinobu Watanabe-Galloway

Journal Articles: Epidemiology

PURPOSE: Rural (vs urban) patients experience poorer cancer outcomes and are less likely to be engaged in cancer prevention, such as screening. As part of a community needs assessment, we explored rural cancer survivors' and caregivers' experiences, perceptions, and attitudes toward cancer care services.

METHODS: We conducted 3 focus groups (N = 20) in Spring 2021 in rural Nebraska.

FINDINGS: Three patterns of cancer diagnosis were regular care/screening without noticeable symptoms, treatment for symptoms not initially identified as cancer related, and symptom self-identification. Most participants, regardless of how diagnosis was made, had positive experiences with timely referral for testing (imaging …