Medicine and Health Sciences Commons^™

Evaluation Of Processing Technique For High-Moisture And Dry Corn On Nutrient Digestion When Fed To Finishing Cattle, Caitlin A. Coulson, Mitch M. Norman, Nicole M. Woita, Hannah C. Wilson, Kylie M. Butterfield, Tyler J. Spore, Galen E. Erickson

Nebraska Beef Cattle Reports

A digestion trial was conducted to determine the effect of corn milling method when processing dry or high-moisture corn on nutrient digestion. Treatments were evaluated as a 2 × 2 factorial with the first factor as corn type [dry corn or high-moisture corn] and second factor as mill type [roller mill or hammer mill]. Feeding high-moisture corn decreased the amount of excreted dry matter and organic matter regardless of processing method, but there tended to be an interaction between corn type and milling method for digestibility. There was no difference between milling treatments fed as high-moisture corn, but hammer milled …

Impact Of Steam-Flaked Rye Fed In Combination With Steam-Flaked Corn On Performance And Carcass Characteristics Of Yearling Steers, Samantha K. Wagner, Braden T. Troyer, Levi J. Mcphillips, Rebecca S. Brattain, Galen E. Erickson

Nebraska Beef Cattle Reports

A finishing study evaluated the effect of feeding steam-flaked rye on performance and carcass characteristics of yearling steers. Treatments consisted of different ratios of steam-flaked rye to steam-flaked corn. The ratios were 0:100, 25:75, 50:50, and 100:0 rye:corn. Increasing inclusions of rye linearly decreased final body weight, dry matter intake, average daily gain, and hot carcass weight. As a result, feed conversion was poorer as rye replaced corn. Carcass characteristics reflected lower gain with linear decreases in marbling score, ribeye area, and backfat thickness. There was no difference in yield grade among treatments. Based on dietary energy calculated from performance, …

Evaluating Performance Of Cattle Fed Steam-Flaked Corn Based Finishing Diets Fed Increasing Inclusions Of Wet Or Modified Distillers Grains, Braden C. Troyer, Levi J. Mcphillips, Mitchell M. Norman, Galen E. Erickson

Nebraska Beef Cattle Reports

A finishing trial using 560 calf-fed steers was conducted to evaluate the effect of distillers type and inclusion on finishing cattle performance and carcass characteristics in steam-flaked corn based diets. Treatments were applied in a 2 × 3 + 1 factorial arrangement, with the first factor being distillers type (modified distillers grains plus solubles or wet distillers grains plus solubles) and the second factor being distillers grains inclusion of 10%, 20%, or 30%, as well as a control diet containing no distillers. There was an interaction between inclusion and type of distillers for feed conversion. A linear improvement in feed …

Effect Of Finishing Cattle With Blends Of High Moisture And Steam-Flaked Corn With And Without Distillers Grains, Braden C. Troyer, Zac C. Carlson, Levi J. Mcphillips, Mitchell M. Norman, Andrea K. Watson, J. C. Macdonald, Galen E. Erickson

Nebraska Beef Cattle Reports

The objective of this study was to determine the impacts of feeding different ratios of high-moisture corn and steam-flaked corn in diets with or without distillers grains and test for an associative effect between grain processing methods. Steers (n=120; BW=775 ± 15.6 lb) were assigned randomly to one of 8 diets. Diets tested included 100:0, 75:25, 50:50, 25:75, and 0:100 of high-moisture corn:steam-flaked corn in diets with 20% modified distillers grains or 100:0, 50:50, and 0:100 in diets without distillers grains. There was an interaction observed for average daily gain as gain improved in 50:50 blends of HMC:SFC in diets …

Characterizing Digestion Traits Of Novel Corn Bran Products, Jiehua Xiong, Chanon Suntara, Rebecca Sjostrand, Tyler Spore, Maggie Youngers, Rick Stock, Galen E. Erickson, J. C. Macdonald

Nebraska Beef Cattle Reports

A digestion study was conducted to evaluate novel corn bran products from Cargill Corn Milling on nutrient digestibility in beef steers. Three bran products (Bran A/B/C) were included at 70% of diet dry matter of TRT A, B and C, with an internal control (SFC control) diet which consisted of 70% SFC. The SFC control exhibited the greatest dry matter (DM), organic matter (OM) and starch digestibility, and the least neutral detergent fiber (NDF) digestibility. Among TRT A, B and C when bran products were included at 70%, there was no difference in DM or OM intake and digestibility. NDF …

Interaction Of Sweet Bran Inclusion And Corn Processing Method In Beef Finishing Diets On Digestibility, Rebecca L. Sjostrand, Kathlyn Hauxwell, Maggie Youngers, Rick Stock, J. C. Macdonald, Galen E. Erickson

Nebraska Beef Cattle Reports

Six ruminally and duodenally fistulated steers were utilized in a 6 × 6 Latin square design to evaluate the interaction of corn processing method and Sweet Bran inclusion in finishing diets on total tract digestibility and rumen fermentation characteristics. Treatments were designed as a 2 × 3 factorial, with one factor as corn processing method (steam-flaked corn or a blend of high-moisture and dry-rolled corn) and the second factor as Sweet Bran inclusion at 0, 20, or 40% of diet dry matter. Cattle fed steam-flaked corn diets had greater starch digestibility while cattle fed high-moisture/ dry-rolled corn diets had greater …

Evaluation Of Models To Predict Dry Matter Intake Of Forage Based Diets, Aksel Wiseman, Andrea K. Watson, Rick Stock, Terry Klopfenstein

Nebraska Beef Cattle Reports

Dry matter intake (DMI) data from growing cattle experiments at the Eastern Nebraska Research and Extension Center were summarized in order to evaluate the accuracy of model predicted DMI. Cattle were fed individually (n = 78) or in pens (n = 15) and predicted DMI using the Beef Cattle Nutrient Requirements Model (BCNRM, 2016) was compared to observed DMI. The model over predicted DMI when total digestible nutrients (TDN) was less than 64%, under predicted DMI when dietary TDN was greater than 64%, and had a low accuracy, explaining less than 22% of the variation in DMI. An equation to …

Interaction Of Urea With Frequency And Amount Of Distillers Grains Supplementation For Growing Steers, Haley F. Linder, Zachary E. Carlson, M. E. Drewnoski, J. C. Macdonald

Nebraska Beef Cattle Reports

A study was conducted to determine the interaction of urea with the frequency and amount of distillers grain supplementation for growing steers consuming forage. Steers were individually fed for 84 d and received ad libitum grass hay and 1 of 8 treatments. Treatment design was a 2 × 2 × 2 factorial. Supplement was fed either every day or 3x/ week, amount of supplement fed was 13.99 lb/week or 28.00 lb/week, and contained either no urea or 1.3% urea. Supplementation frequency and the inclusion of urea did not impact steer average daily gain. The amount of supplement did impacted steer …

Impact Of Urea On Corn Silage Growing Cattle Diets, Tyler J. Spore, Hannah C. Wilson, Nolan R. Meier, Galen E. Erickson, James C. Macdonald, Terry J. Klopfenstein, Andrea K. Watson

Nebraska Beef Cattle Reports

Two experiments were conducted to evaluate the effects of increasing urea in a corn silage growing cattle diet and ensiling time impact on rumen undegradable protein content of corn silage. Four treatments (urea inclusion at 0, 0.5, 1, and 1.5% of diet dry matter) were evaluated in diets containing 95% corn silage using 10 ruminally and duodenally cannulated heifers. Corn silage was sampled 5 times (every 32 days) to determine rumen undegradable protein content. Intake and total tract digestibility of dry matter, organic matter, and neutral detergent fiber all increased linearly with increasing inclusion of urea in the diet. Measured …

Growth Performance In Livestock With Stress-Induced Low Birthweight Is Recovered By Clenbuterol Administration, Rachel L. Gibbs, Rebecca M. Swanson, Joslyn K. Beard, Ty B. Schmidt, Jessica Lynn Petersen, Dustin T. Yates

Nebraska Beef Cattle Reports

Stress in pregnant livestock causes pathological low birthweight of the offspring and diminishes their muscle growth capacity. Using sheep as a model for beef cattle, this study determined that the limited growth capacity of offspring with stress-induced low birthweight could be recovered by postnatal treatments. Muscle in these animals has less growth-promoting β2 adrenergic activity and thus the injectable β2 adrenergic stimulant clenbuterol was used as a daily treatment. Lambs with stress-induced low birthweight continued to exhibit impaired muscle growth and feed efficiency well past the normal age for weaning. In addition, they began to put on excess fat around …

Zipaterol Supplementation Improved Indicators Of Well-Being, But Not Growth In Heat-Stressed Red Angus Steers, Pablo C. Grijalva, Duarte E. Diaz, Samuel R. Garcia, Ty B. Schmidt, Jessica Lynn Petersen, Dustin T. Yates

Nebraska Beef Cattle Reports

The effects of zilpaterol (β2 agonist) supplementation on respiration rate, body temperature, growth, and carcass traits were studied in chronically heat-stressed feedlot steers. Through a collaborative partnership with the University of Arizona, Red Angus steers were heat stressed (90-105^oF) and fed zilpaterol-supplemented rations (Thermo-neutral control steers were pair-fed to the average feed intake of heat-stressed steers) for 30 days. Hot and cold carcass weights for heat-stressed cattle were 3% less than for controls, despite equal feed intake. Zilpaterol did not affect growth but improved the heat stress-induced hyperventilation and elevated body temperatures. Lighter carcass weights in heat-stressed cattle …

Inflammatory Modulators Improve Daily Gain Of Heat-Stressed Wethers, Micah S. Most, Pablo C. Grijalva, Dustin T. Yates

Nebraska Beef Cattle Reports

Inflammation during heat stress may mediate poor growth in livestock. The effects of anti-imflammatory treatments on muscle growth during chronic heat stress were evaluated by using meat lambs as a smaller cheaper model for feedlot steers. Wethers were maintained in normal (75^oF) or heat stress (105^oF for 12 hours/day, 85^oF for 12 hours/day) environments for 30 days and received dexamethasone injections every 3 days, oral fish oil supplementation twice daily, or no intervention. Growth was tracked and muscles were weighed when harvested afterward. Dexamethasone and fish oil both increased average daily gain over the …

Impact Of Cow Size On Economic Profitability In Cow-Calf And Feedlot Production Systmes, Robert L. Ziegler, Elliott James Dennis, J. A. Musgrave, T. L. Meyer, R. Funston, Kathryn J. Hanford, J. C. Macdonald, J. Travis Mulliniks

Nebraska Beef Cattle Reports

This study retrospectively evaluated the effect of cow size on profitability in the cow-calf segment and retained ownership of steer calves in the feedlot. Data were collected between 2005 to 2017 from the cowherd at Gudmundsen Sandhills Laboratory. From these data, two separate herds were assumed, one consisting of small-sized (1,000 lb) cows and another consisting of large-sized cows (1,220 lb) for the GSL cowherd. Larger cows weaned larger calves and produced heavier carcass weights of steers at slaughter. However, smaller cows generated more total pounds of output throughout the entire production system based on more calves retained in feedlots …

Statistics Used In The Nebraska Beef Cattle Report And Teir Purpose, University Of Nebraska-Lincoln

Nebraska Beef Cattle Reports

Te purpose of beef cattle and beef product research at UNL is to provide reference information that represents the various populations (cows, calves, heifers, feeders, carcasses, retail products, etc) of beef production. Obviously, the researcher cannot apply treatments to every member of a population; therefore he/she must sample the population. Te use of statistics allows the researcher and readers of the Nebraska Beef Cattle Report the opportunity to evaluate separation of random (chance) occurrences and real biological effects of a treatment. Following is a brief description of the major statistics used in the beef report. For a more detailed description …

Economics Of Grazing Calves On Oats Planted After Corn Silage In Eastern Nebraska, Kallie J. Calus, Mckenna M. Brinton, Benjamin H. Hansen, Kristen M. Ulmer, Zachery E. Carlson, Fred H. Hilscher, M. E. Drewnoski, Jay Parsons, J. C. Macdonald

Nebraska Beef Cattle Reports

A five-year study (2015–2019) evaluated profitability of planting and grazing an oats cover crop after early harvested corn silage in eastern Nebraska. Oats were typically planted in the first week of September. Stocking rate ranged from 1.7 to 0.6 steers per acre and was based on oats biomass. Calves were turned out in early November each year and allowed to graze until oats biomass or weather limited intake. Grazing period ranged from 30 to 69 days. Average daily gain of calves ranged from 3.35 to 1.29 pounds with an average of 1.97 pounds. Shortened grazing seasons in some years were …

The Role Of Emergency Departments For Antimicrobial Stewardship In Covid-19 Pandemic; The Time Is Now, Madiha Ismail, Nazeer Najeeb Kapadia, Sara Usman

Department of Emergency Medicine

No abstract provided.

Plethora Of Cranial Nerve Palsies: A Problematic Presentation Of Myasthenia Gravis, Nichole Birdsong, Sean Gibbs, Jerry Banks

South Atlantic Division GME Research Day 2022

No abstract provided.

Providing A Helping Hand: Metabolic Regulation Of T Follicular Helper Cells And Their Association With Disease., Colleen L Mayberry, Natalie A Logan, John J Wilson, Chih-Hao Chang

Faculty Research 2022

T follicular helper (Tfh) cells provide support to B cells upon arrival in the germinal center, and thus are critical for the generation of a robust adaptive immune response. Tfh express specific transcription factors and cellular receptors including Bcl6, CXCR5, PD-1, and ICOS, which are critical for homing and overall function. Generally, the induction of an immune response is tightly regulated. However, deviation during this process can result in harmful autoimmunity or the inability to successfully clear pathogens. Recently, it has been shown that Tfh differentiation, activation, and proliferation may be linked with the cellular metabolic state. In this review …

Editorial: Stromal And Immune Microenvironment In Breast Cancer Metastasis., Xin Lu, Xia Liu, Toni Celià-Terrassa, Guangwen Ren

Faculty Research 2022

No abstract provided.

Epidermal Growth Factor Receptor Inhibition Is Protective In Hyperoxia-Induced Lung Injury., Zachary M Harris, Ying Sun, John Joerns, Brian Clark, Buqu Hu, Asawari Korde, Lokesh Sharma, Hyeon Jun Shin, Edward P Manning, Lindsey Placek, Derya Unutmaz, Gail Stanley, Hyung Chun, Maor Sauler, Govindarajan Rajagopalan, Xuchen Zhang, Min-Jong Kang, Jonathan L Koff

Faculty Research 2022

AIMS: Studies have linked severe hyperoxia, or prolonged exposure to very high oxygen levels, with worse clinical outcomes. This study investigated the role of epidermal growth factor receptor (EGFR) in hyperoxia-induced lung injury at very high oxygen levels (>95%).

RESULTS: Effects of severe hyperoxia (100% oxygen) were studied in mice with genetically inhibited EGFR and wild-type littermates. Despite the established role of EGFR in lung repair, EGFR inhibition led to improved survival and reduced acute lung injury, which prompted an investigation into this protective mechanism. Endothelial EGFR genetic knockout did not confer protection. EGFR inhibition led to decreased levels …

Pharmacokinetic, Pharmacodynamic, And Transcriptomic Analysis Of Chronic Levetiracetam Treatment In 5xfad Mice: A Model-Ad Preclinical Testing Core Study, Kristen D. Onos, Sara K. Quinney, David R. Jones, Andrea R. Masters, Ravi S Pandey, Kelly J Keezer, Carla Biesdorf, Ingrid F. Metzger, Jill A. Meyers, Johnathon Peters, Scott C. Persohn, Brian P. Mccarthy, Amanda A. Bedwell, Lucas L. Figueiredo, Zackary A. Cope, Michael Sasner, Gareth R Howell, Harriet M. Jackson, Adrian L. Oblak, Bruce T. Lamb, Gregory W. Carter, Stacey J. Rizzo, Paul R. Territo

Faculty Research 2022

INTRODUCTION: Hyperexcitability and epileptiform activity are commonplace in Alzheimer's disease (AD) patients and associated with impaired cognitive function. The anti-seizure drug levetiracetam (LEV) is currently being evaluated in clinical trials for ability to reduce epileptiform activity and improve cognitive function in AD. The purpose of our studies was to establish a pharmacokinetic/pharmacodynamic (PK/PD) relationship with LEV in an amyloidogenic mouse model of AD to enable predictive preclinical to clinical translation, using the rigorous preclinical testing pipeline of the Model Organism Development and Evaluation for Late-Onset Alzheimer's Disease Preclinical Testing Core. METHODS: A multi-tier approach was applied that included quality assurance …

An In Vitro Evaluation Of The Kontrolflex Accufile Hand File, Mia Tittle

Orthodontics and Endodontics Theses

The aims of this study were to determine the efficacy of the KontrolFlexTM AccufileTM compared to the READY•STEEL™ Flexofile® using an electronic apex locator and to evaluate the instrument’s design via scanning electron microscopy. Actual canal lengths of thirty extracted teeth were determined under magnification. An alginate model was used to determine experimental canal lengths with the Root ZX II apex locator and size #10 Accufiles and Flexofiles. Differences between actual lengths and experimental lengths were compared with Student’s t test. The average experimental lengths were short of the actual length by -0.10 mm (±0.34) and -0.12 mm (±0.16) for …

The Socioeconomic Gradient Of Alcohol Use, Charles Dh Parry, Gianna Gayle H. Amul

Ateneo School of Government Publications

No abstract provided.

What Can Aphasia Tell Us About How The First-Acquired Language Is Instantiated In The Brain?, Mira Goral

Publications and Research

Recent neurolinguistic theories converge on the hypothesis that the languages of multilingual people are processed as one system in the brain. One system for the multiple languages is also at the core of a translanguaging framework of multilingualism—a framework that focuses on each speaker’s complete linguistic repertoire rather than on the separate languages they know. However, evidence from neuroimaging studies suggests at least some nonoverlapping activations of the first-acquired language (L1) and other (non-L1) languages of multilingual people, especially when the age of acquisition and/or levels of proficiency differ across the languages. Neurolinguistic studies of acquired language disorders have demonstrated …

The Influence Of Psychosocial And Sociocultural Situatedness Within Organisations On The Practice Of Mindfulness Among Employees: A Systematic Review Of Literature, Bhuvan Israni, Niamh Imbusch

Other resources

No abstract provided.

Perceived Social Support And Stress: A Study Of 1st Year Students In Ireland, Lavinia Mclean, David Gaul, Rebecca Penco

Articles

Social support is consistently associated with positive outcomes for students, in terms of wellbeing and academic achievement. For first year students, social support offers a way to deal with stressors associated with the challenge of transitioning to university. The current research was conducted with a range of first year students (n = 315) early in their first semester in university. Both male and female students reported moderate levels of social support and perceived stress, while those with higher levels of social support reported lower levels of stress. Gender differences were apparent in both the levels and sources of social …

Opportunities And Challenges To Emergency Department-Based Hiv Testing Services And Self-Testing Programs: A Qualitative Study Of Healthcare Providers And Patients In Kenya, Adam R. Aluisio, Scarlett J. Bergam, Felix A. Otieno, Beatrice Ngila, Janet Sugut, Rose Bosire, David Bukusi, John Kinuthia, Kate M. Guthrie, David A. Katz, Carey Farquhar, Michael J. Mello

School of Medicine and Health Sciences Student Works

No abstract provided.

Uncertainty, Scarcity And Transparency: Public Health Ethics And Risk Communication In A Pandemic, Abigail Lowe, Teck Chuan Voo, Lisa M. Lee, Kelly K. Dineen Gillespie, Christy Feig, Alva O. Ferdinand, Seema Mohapatra, David Brett-Major, Matthew K. Wynia

Journal Articles: Epidemiology

Communicating public health guidance is key to mitigating risk during disasters and outbreaks, and ethical guidance on communication emphasizes being fully transparent. Yet, communication during the pandemic has sometimes been fraught, due in part to practical and conceptual challenges around being transparent. A particular challenge has arisen when there was both evolving scientific knowledge on COVID-19 and reticence to acknowledge that resource scarcity concerns were influencing public health recommendations. This essay uses the example of communicating public health guidance on masking in the United States to illustrate ethical challenges of developing and conveying public health guidance under twin conditions of …

Peroxide Antimalarial Drugs Target Redox Homeostasis In Plasmodium Falciparum Infected Red Blood Cells, Ghizal Siddiqui, Carlo Giannangelo, Amanda De Paoli, Anna Katharina Schuh, Kim C. Heimsch, Dovile Anderson, Timothy G. Brown, Christopher A. Macraild, Jianbo Wu, Xiaofang Wang, Yuxiang Dong, Jonathan L. Vennerstrom, Katja Becker, Darren J. Creek

Journal Articles: Pharmaceutical Sciences

Plasmodium falciparum causes the most lethal form of malaria. Peroxide antimalarials based on artemisinin underpin the frontline treatments for malaria, but artemisinin resistance is rapidly spreading. Synthetic peroxide antimalarials, known as ozonides, are in clinical development and offer a potential alternative. Here, we used chemoproteomics to investigate the protein alkylation targets of artemisinin and ozonide probes, including an analogue of the ozonide clinical candidate, artefenomel. We greatly expanded the list of proteins alkylated by peroxide antimalarials and identified significant enrichment of redox-related proteins for both artemisinins and ozonides. Disrupted redox homeostasis was confirmed by dynamic live imaging of the glutathione …

Advocate Against Adversity, Melany Kelly, Hermela Shimels, Zariah Bailey, Kennedy Carter

DC Health and Academic Prep Program (DC HAPP)

Our project is focused on the social determinants of maternal healthcare throughout urban areas in the United States and, more specifically, the different wards in DC. This project aims to shed light on how racial and ethnic disparities, in addition to other social determining factors, are contributing to high infant mortality rates in the DC area. It also proposes potential public health initiatives that seeks to address and combat these differences.