Medicine and Health Sciences Commons^™

Relationship Between Nordic Hamstring Strength And Maximal Voluntary Eccentric, Concentric And Isometric Knee Flexion Torque, Satoru Nishida, Masatoshi Nakamura, Ryosuke Kiyono, Shigeru Sato, Koki Yasaka, Riku Yoshida, Kazunori Nosaka

Research outputs 2022 to 2026

Nordic hamstring exercise is performed to prevent knee flexor muscle strain injuries and used to assess their injury risks. However, what exactly Nordic hamstring strength indicates is not clear. We investigated the relationship between Nordic hamstring strength and maximal voluntary contraction (MVC) torque of the knee flexors measured by an isokinetic dynamometer. Sixteen healthy young men who had not experienced hamstring strain injuries participated in the study. In Nordic hamstring, each participant was instructed to lean forward as far as possible in 3 s (approximately 30/s), and force at the ankle joint of the dominant leg was measured during the …

Does Midwifery-Led Care Demonstrate Care Ethics: A Template Analysis, Kate Buchanan, Elizabeth Newnham, Deborah Ireson, Clare Davison, Sara Bayes

Research outputs 2014 to 2021

Background: Ethical care in maternity is fundamental to providing care that both prevents harm and does good, and yet, there is growing acknowledgement that disrespect and abuse routinely occur in this context, which indicates that current ethical frameworks are not adequate. Care ethics offers an alternative to the traditional biomedical ethical principles.

Research aim: The aim of the study was to determine whether a correlation exists between midwifery-led care and care ethics as an important first step in an action research project.

Research design: Template analysis was chosen for this part of the action research. Template analysis is a design …

A Unique Sarcopenic Progression In The Mouse Rotator Cuff, Gretchen A Meyer, Karen C Shen

2020-Current year OA Pubs

BACKGROUND: In response to chronic injury, the muscles of the rotator cuff (RC) experience a unique degeneration characterized by extensive fatty infiltration and loss of contractile function. Human studies suggest this degeneration is also a feature of RC sarcopenia and may precede RC injury. In this study, we investigated whether RC muscles exhibit a similar unique sarcopenia in the mouse.

METHODS: Male and female mice were subdivided into four age groups: 3, 9, 18, and 24 months. The supraspinatus (SS) and infraspinatus muscles of the RC and the tibialis anterior (TA) muscle of the hindlimb were assessed. Muscle mass, contractile …

Clinical Image: Calcinosis Cutis Universalis In A Patient With Polymyositis/Scleroderma Overlap Syndrome, Katie Carbonell, Nicole Droz

2020-Current year OA Pubs

No abstract provided.

Mental Health In The Uk Biobank: A Roadmap To Self-Report Measures And Neuroimaging Correlates, Rosie K Dutt, Kayla Hannon, Ty O Easley, Joseph C Griffis, Wei Zhang, Janine D Bijsterbosch

2020-Current year OA Pubs

The UK Biobank (UKB) is a highly promising dataset for brain biomarker research into population mental health due to its unprecedented sample size and extensive phenotypic, imaging, and biological measurements. In this study, we aimed to provide a shared foundation for UKB neuroimaging research into mental health with a focus on anxiety and depression. We compared UKB self-report measures and revealed important timing effects between scan acquisition and separate online acquisition of some mental health measures. To overcome these timing effects, we introduced and validated the Recent Depressive Symptoms (RDS-4) score which we recommend for state-dependent and longitudinal research in …

Is Tissue Still The Issue? The Promise Of Liquid Biopsy In Uveal Melanoma, Daniël P. De Bruyn, Aaron B. Beasley, Robert M. Verdijk, Natasha M. Van Poppelen, Dion Paridaens, Ronald O.B. De Keizer, Nicole C. Naus, Elin S. Gray, Annelies De Klein, Erwin Brosens, Emine Kiliç

Research outputs 2022 to 2026

Uveal melanoma (UM) is the second most frequent type of melanoma. Therapeutic options for UM favor minimally invasive techniques such as irradiation for vision preservation. As a consequence, no tumor material is obtained. Without available tissue, molecular analyses for gene expression, mutation or copy number analysis cannot be performed. Thus, proper patient stratification is impossible and patients' uncertainty about their prognosis rises. Minimally invasive techniques have been studied for prognostication in UM. Blood-based biomarker analysis has become more common in recent years; however, no clinically standardized protocol exists. This review summarizes insights in biomarker analysis, addressing new insights in circulating …

Mathematics For The Masses: Door-To-Door Missionaries Of Math And Twelve-Step Recovery Programs, Daniel S. Helman

Journal of Humanistic Mathematics

Conversion of strangers, or proselytizing, is a feature of a range of groups for religious, organizational and other aims. In twelve-step recovery programs, such as Alcoholics Anonymous, belief in a higher power is a requirement for working the steps to recovery. People are encouraged to find a higher power of their own understanding. This paper presents a model for using mathematics as a higher power, and shows how recovery works with mathematics in that role instead of a more traditional higher power such as God. A contemplative definition of math is given along with a description of a three-categoried epistemology: …

Culturally Safe And Integrated Primary Health Care: A Case Study Of Yerin Eleanor Duncan Aboriginal Health Services’ Holistic Model, Julieann Coombes, Patricia Cullen, Keziah Bennett-Brook, Marlene Longbottom, Tamara Mackean, Belinda Field, Vickie Parry

Journal of the Australian Indigenous HealthInfoNet

Objective

To understand the importance of culturally safe integrated primary health care for Aboriginal families in the Central Coast of New South Wales, where their social and emotional wellbeing is impacted through a range of health issues related to domestic and family violence.

Methods
An Indigenous methodology of yarning through conversational semi-structured interviews with seven primary health care workers at Yerin, an Aboriginal Community Controlled Health Service (ACCHS) in New South Wales. Yarning sessions explored factors that enable and/or inhibit the provision of holistic and comprehensive trauma and culturally informed responses to Aboriginal and Torres Strait Islander women who experience …

Evaluating Patient Experience At A Novel Health Service For Aboriginal And Torres Strait Islander Prisoners: A Pilot Study, Lachlan Arthur, Ana Herceg, Heidi Shukralla, Jason Payne, Julie Tongs Oam

Journal of the Australian Indigenous HealthInfoNet

Background
The Winnunga Alexander Maconochie Centre Health and Wellbeing Service (AMCHWS) is the first prison health service operated by an Aboriginal Community Controlled Health Organisation in Australia. This pilot study developed and implemented a patient experience survey to evaluate the novel model of healthcare delivered by the Winnunga AMCHWS to Aboriginal and Torres Strait Islander prisoners.

Methods
Patients accessing the Winnunga AMCHWS between February and May 2020 were invited to participate in the study. Descriptive data were analysed and compiled for demographics, patient satisfaction, patient perception of care quality, cultural safety, and patient thoughts on the Winnunga AMCHWS.

Findings
Sixteen …

Protocols For An Aboriginal-Led, Multi-Methods Study Of The Role Of Aboriginal And Torres Strait Islander Health Workers, Practitioners And Liaison Officers In Quality Acute Health Care, Annabelle Wilson, Tamara Mackean, Liz Withall, Eileen M. Willis, Odette Pearson, Colleen Hayes, Kim O'Donnell, Janet Kelly, Kerry Taylor, Judith Dwyer, Elizabeth Bourke, Kate Hunter, Lorna Murakami-Gold, Rebecca Ivers, Fran Baum

Journal of the Australian Indigenous HealthInfoNet

Objectives
Aboriginal and Torres Strait Islander Health Workers/Practitioners and Liaison Officers play an important, often critical role providing advocacy and cultural and emotional support for Aboriginal and Torres Strait Islander patients. The main goals of this research are to explore i) how Aboriginal and Torres Strait Islander Health Workers/Practitioners and Liaison Officers are integrated in the routine delivery of care for Aboriginal and Torres Strait Islander peoples in hospital, and ii) how the role of Aboriginal and Torres Strait Islander Health Workers/Practitioners and Liaison Officers facilitates quality health outcomes.

Methods
This study is being conducted in three different hospitals using …

Do Medical Residents With Rural Upbringing Show Less Decline In Empathy During Training? A Report From A Rural Family Medicine Residency, William J. Crump, Craig H. Ziegler, R. Steve Fricker

Marshall Journal of Medicine

Purpose

Our focus in this study was to determine if demographic variables, including specifically rural upbringing, showed any association with a measure of empathy among family medicine residents at a rural site.

Methods

We surveyed 40 residents annually using the Jefferson Scale of Empathy (JSE) from 2016 to 2020 and compared scores between residents with rural vs urban hometowns. The response rate was 98/99 (99%) of completed survey opportunities.

Findings

There was no significant difference in JSE scores of rural vs urban residents at baseline, and both groups showed a decline after the PG-1 year. However, the rural-raised residents showed …

Over-The-Counter Analgesic Use Patterns In Appalachian Older Adults, Focusing On Non-Steroidal Anti-Inflammatory Drugs, Courtney Wellman Md, Jordan Ratcliffe Bs, William Rollyson Md, Adam M. Franks Md, Mike Grome Pa-C, Robert Walker Md

Marshall Journal of Medicine

Introduction

Over-the-counter (OTC) medications are commonly used by elderly patients to self-manage pain symptoms. Medications such as non-steroidal anti-inflammatory drugs (NSAIDs), acetaminophen and topical analgesics are readily available and therefore may seem harmless to patients. In the growing population of those 65 years and older, providers need to inquire about OTC medication use due to the increased risk for adverse reactions in this population. Complications related to these medications can be worsened by chronic disease, variable metabolism, polypharmacy, etc. which become more common in the older adults.

Methods

A survey was created to determine the prevalence and habits of OTC …

Adult Pulmonary Langerhans Cell Histiocytosis With Osseous Involvement: Understanding This Rare Mimic Of Malignancy, Samantha A. Smith Ms Iii, Adam M. Franks Md, William Rollyson Ms Iv, Doreen Griswold, Tammy Bannister Md

Marshall Journal of Medicine

Langerhans cells are dendritic cells that form the antigenic barrier of the human body. They occur in nearly any tissue but are most prevalent in the skin, submucosa of the bronchial tree, and other mucosae. Langerhans Cell Histiocytosis (LCH) develops when these cells damage the tissues in which they reside through a combination of inflammatory and monoclonal stimulation. The pulmonary variant of LCH involves the lung parenchyma and creates a wide variety of disturbances: pulmonary hypertension and both obstructive and restrictive lung disease. Osseous involvement, in addition to the pulmonary variant, presents with pulmonary masses and lytic bone lesions, which …

Motor Symptoms As A Prodrome To Schizophrenia, Adam Schindzielorz, Hunter Edwards, Kelly Melvin

Marshall Journal of Medicine

Schizophrenia occurs in 1% of the population and is severely impairing to those afflicted. Thereby, it is of the utmost importance to recognize and treat the disorder as early as possible. For the last several decades research has attempted to elucidate a variety of predictive factors in order to aid in the identification of patients at high risk of developing a schizophrenia spectrum disorder. These factors have included premorbid or prodromal movement symptoms. The literature has identified motor aberrations beginning early in life, in some cases even in infancy, ranging from neonatal hypotonicity to facial and upper body dyskinesia. …

A Tribute To Franklin Shuler, M.D., Ph.D., C.I.M.E. (1967-2021), Abigail Tolbert, Dipali Nemade

Marshall Journal of Medicine

Dr. Franklin Shuler was a well-known Orthopaedic Surgeon amongst Marshall Health. He made breakthroughs in research, was a phenomenal mentor, and took care of his community and family.

For 4 years, Dr. Shuler fought HLH, a rare autoimmune disorder, that eventually took his life on January 5, 2020. He made his mark at the West Virginia School of Medicine being the first student to graduate with an M.D. and Ph. D with honors. Additionally, he was prestigious in research with accepted publications for 11 consecutive years. Dr. Shuler took pride in his community as well as medical student education as …

In Appreciation: A Thank-You To Our Industrious Reviewers, Darshana T. Shah

Marshall Journal of Medicine

The reputation of the Marshall Journal of Medicine depends on the authors' contribution; however, the standard of the Journal's level of excellence is also a consequence of the efforts of expert peer reviewers. We are grateful to the more than 530 individual reviewers who have contributed to the success of our Journal and enhanced the quality of 260 published papers. It is impossible to overstate the importance of their labor to ensure both the quality and relevance of work published in the Journal. On behalf of the Marshall Journal of Medicine editorial board, I want to express my sincere gratitude …

2022-01-31 Michiganoverview_Covidoutbreak, Michigan Department Of Health & Human Services

Michigan COVID-19 Outbreak Reports

The Outbreak Data page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173_102057---,00.html.

This report is created by the Michigan Department of Health & Human Services from data self-reported by local health departments. Data is updated every week.

COVID-19 outbreaks are generally defined as two or more cases with a link by place and time indicating a shared exposure outside of a household. Local health departments report the number of new and ongoing outbreaks they are investigating by the setting of the outbreak. New outbreaks are those outbreaks that were first identified during the current reporting week. Ongoing outbreaks are …

Andragogy: The Common Thread In The Teaching Of Adults In Colleges Of Education, Criminal Justice, And Health Management, Grant J. Shostak, Larry Acker, Vanessa Vandergraaf

Faculty Scholarship

The Covid-19 pandemic has brought dramatic changes to higher education. Students and educators face challenges never anticipated, including switching classes from on-ground to online and back again, mental fatigue, stress, and burnout. Faculty across disciplines may turn to Andragogy to best teach college students to inform their teaching practices. This paper demonstrates how professors from education, criminal justice, and healthcare management have used andragogical techniques in their classrooms.

The Role Of The Accessory Gene Regulator Operon In Biofilm Formation By Staphylococcus Aureus, Sarah C. Jordan

Pharmaceutical Sciences ETDs

Staphylococcus aureus is a pathogenic bacteria that causes significant morbidity and mortality. As antibiotic resistance by S. aureus continues to be a serious concern, developing novel drug therapies to combat these infections is vital. Quorum sensing inhibitors (QSI) dampen S. aureus virulence and facilitate clearance by the host immune system by blocking quorum sensing signaling that promotes upregulation of the accessory gene regulator (agr) operon. While QSIs have shown therapeutic promise in mouse models of S. aureus infection, their further development has been hampered by the suggestion that agr inhibition promotes biofilm formation. In these studies, we investigated the relationship …

2022-01-31_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …

2022-01-31_Michiganoverview_Covidcounts, Michigan Department Of Health & Human Services

Michigan COVID-19 Confirmed Cases by Date of Onset Data

Data was downloaded as an Excel spreadsheet which appeared in the Public Use Datasets section under the Cumulative Data link of Michigan's Coronavirus webpage, under the url https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173---,00.html.

Cases are aggregated by the date of onset of COVID-19 symptoms, if known, otherwise by laboratory specimen date if known, otherwise by case referral date. Deaths are aggregated by the date of death if known, otherwise by the last date of a change to the case status.

2022-01-31_Michiganoverview_Covidschooloutbreak, Michigan Department Of Health & Human Services

Michigan COVID-19 Outbreak Reports

The School Outbreak Data page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173_102480---,00.html.

This report is created by the Michigan Department of Health & Human Services from data self-reported by local health departments. Data is updated every week.

K-12 School-Related Outbreak Reporting: In accordance with the Council of State and Territorial Epidemiologists' outbreak definition, a K-12 school-associated COVID-19 case (confirmed or probable) is defined as a student, teacher, or staff member physically present in the school setting or participated in a school sanctioned extracurricular activity within 14 days prior to illness onset (or a positive test result) OR …

Online Graduate Certificate In Medication Outcomes, Joanna Burkhardt

Library Impact Statements

No abstract provided.

2022-01-31_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled. COVID case and testing data will be posted three times a week on Mondays, Wednesdays and Fridays.

This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time …

A Twist To The Kirby-Bauer Disk Diffusion Susceptibility Test: An Accessible Laboratory Experiment Comparing Haloferax Volcanii And Escherichia Coli Antibiotic Susceptibility To Highlight The Unique Cell Biology Of Archaea, Heather Schiller, Criston Young, Stefan Schulze, Manuela Tripepi, Mechthild Pohlschroder

College of Life Sciences Faculty Papers

Archaea, once thought to only live in extreme environments, are present in many ecosystems, including the human microbiome, and they play important roles ranging from nutrient cycling to bioremediation. Yet this domain is often overlooked in microbiology classes and rarely included in laboratory exercises. Excluding archaea from high school and undergraduate curricula prevents students from learning the uniqueness and importance of this domain. Here, we have modified a familiar and popular microbiology experiment-the Kirby-Bauer disk diffusion antibiotic susceptibility test-to include, together with the model bacterium Escherichia coli, the model archaeon Haloferax volcanii. Students will learn the differences and similarities between …

2022-01-31 Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

Contains the tables Statewide Hospital Capacity Report for COVID-19, COVID-19 Metrics, Statewide Hospital Available PPE Tracking for COVID-19, as well as the tables PPE Days On Hand and Patient Census.

Zoonotic Pathogens From Illegally Traded Wildlife Justify Adopting The One Health Perspective In Disease Response, Marianne Allison G. Lee, Vinyl Joseph S. Valeza, Jonathan Patrick H. Yan, Ronald Allan L. Cruz

Biology Faculty Publications

Recent studies have described a direct relationship between the illegal wildlife trade (IWT) and the prevalence of zoonotic pathogens in human populations. In the Philippines, the Philippine Integrated Disease Surveillance and Response (PIDSR) framework outlines the monitoring, response, and management of disease outbreaks, but needs to be updated in the wake of zoonoses from IWT. Here, we identified zoonotic pathogens that may be introduced to human populations through the IWT, pinpointed potential outbreak hotspots, and provided recommendations on how to improve the Philippines’ public health response while considering One Health. Using seizure data from the Biodiversity Management Bureau (DENR-BMB) covering …

Essai Sur Le Terrain Du Mini Pipe Strain Meter Du Jniosh Comme Système D’Alerte De Sécurité Lors Des Travaux En Tranchée, André Lan, Bertrand Galy, Satoshi Tamate, Tomohito Hori, Nabutaka Hiraoka

Rapports de recherche scientifique

Les travaux en tranchée exposent les travailleurs à de nombreux risques. Le risque d'effondrement est le plus important et le plus fréquent lors de tels travaux, mais il est malheureusement très souvent sous-estimé, car même un effondrement mineur ou partiel de moins de 1 m3 de sol peut mortellement blesser un travailleur. L'analyse de 59 rapports de la Commission des normes, de l'équité, de la santé et de la sécurité du travail (CNESST) concernant des accidents graves et mortels survenus lors de travaux d'excavation et en tranchée réalisés entre juin 1973 et mai 2015 montre qu'il y a eu 51 …

Field Test Of The Jniosh Mini Pipe Strain Meter As A Safety Alert System During Trench Work, André Lan, Bertrand Galy, Satoshi Tamate, Tomohito Hori, Nabutaka Hiraoka

Rapports de recherche scientifique

Les travaux en tranchée exposent les travailleurs à de nombreux risques. Le risque d'effondrement est le plus important et le plus fréquent lors de tels travaux, mais il est malheureusement très souvent sous-estimé, car même un effondrement mineur ou partiel de moins de 1 m3 de sol peut mortellement blesser un travailleur. L'analyse de 59 rapports de la Commission des normes, de l'équité, de la santé et de la sécurité du travail (CNESST) concernant des accidents graves et mortels survenus lors de travaux d'excavation et en tranchée réalisés entre juin 1973 et mai 2015 montre qu'il y a eu 51 …

Conformational Flexibility And Local Frustration In The Functional States Of The Sars-Cov-2 Spike B.1.1.7 And B.1.351 Variants: Mutation-Induced Allosteric Modulation Mechanism Of Functional Dynamics And Protein Stability, Gennady M. Verkhivker

Mathematics, Physics, and Computer Science Faculty Articles and Research

Structural and functional studies of the SARS-CoV-2 spike proteins have recently determined distinct functional states of the B.1.1.7 and B.1.351 spike variants, providing a molecular framework for understanding the mechanisms that link the effect of mutations with the enhanced virus infectivity and transmissibility. A detailed dynamic and energetic analysis of these variants was undertaken in the present work to quantify the effects of different mutations on functional conformational changes and stability of the SARS-CoV-2 spike protein. We employed the efficient and accurate coarse-grained (CG) simulations of multiple functional states of the D614G mutant, B.1.1.7 and B.1.351 spike variants to characterize …