Medicine and Health Sciences Commons^™

Gower's "Herte-Thoght": Thinking, Feeling, Healing, Eve Salisbury

Accessus

While much has been said about the ethical principles of Gower's poetry, less has been said about his understanding of the body, its principal organs, and its relation to the medical discourse of the time. This short paper, presented initially as part of the "Hope and Healing Symposium" sponsored by The Gower Project, approaches the poet's work from a more medically inflected point of view, one that suggests a stronger kinship between the material body and its use as a metaphor for the body politic. Gower appears to be situated within a continuing debate launched by Aristotle and taken up …

The Emerging Role Of Deubiquitylating Enzymes As Therapeutic Targets In Cancer Metabolism., Rongfu Tu, Junpeng Ma, Peng Zhang, Ye Kang, Xiaofan Xiong, Junsheng Zhu, Miao Li, Chengsheng Zhang

Faculty Research 2022

Cancer cells must rewire cellular metabolism to satisfy the unbridled proliferation, and metabolic reprogramming provides not only the advantage for cancer cell proliferation but also new targets for cancer treatment. However, the plasticity of the metabolic pathways makes them very difficult to target. Deubiquitylating enzymes (DUBs) are proteases that cleave ubiquitin from the substrate proteins and process ubiquitin precursors. While the molecular mechanisms are not fully understood, many DUBs have been shown to be involved in tumorigenesis and progression via controlling the dysregulated cancer metabolism, and consequently recognized as potential drug targets for cancer treatment. In this article, we summarized …

Combination Of Amphiphilic Cyclic Peptide [R4W4] And Levofloxacin Against Multidrug-Resistant Bacteria, Muhammad Imran Sajid, Sandeep Lohan, Shun Kato, Rakesh Kumar Tiwari

Pharmacy Faculty Articles and Research

Bacterial resistance is a growing global concern necessitating the discovery and development of antibiotics effective against the drug-resistant bacterial strain. Previously, we reported a cyclic antimicrobial peptide [R₄W₄] containing arginine (R) and tryptophan (W) with a MIC of 2.67 µg/mL (1.95 µM) against methicillin-resistant Staphylococcus aureus (MRSA). Herein, we investigated the cyclic peptides [R₄W₄] or linear (R₄W₄) and their conjugates (covalent or noncovalent) with levofloxacin (Levo) with the intent to improve their potency to target drug-resistant bacteria. The physical mixture of the Levo with the cyclic [R_{4 …}

A Macro Social Examination Of The Relationship Between Disabilities And Crime Using Neighborhood And County Level Data, Natasha A. Baloch

USF Tampa Graduate Theses and Dissertations

Over the last few decades, there has been a consistent increase in mental illnesses in the US population. This has also lead to increased interactions of those with mental illnesses and/or disabilities with law enforcement and the criminal justice system. Despite these instances, there is limited research on the relationship between disabilities, mental health issues and crime in the large body of criminological research. Further, the current extant research is a) outside the field of Criminology, b) primarily focuses on those with only intellectual or developmental disabilities and/or c) does not examine this relationship at the macro level, despite evidence …

The Relationship Of Hair Glucocorticoid Levels To Immunological And Virological Outcomes In A Large Cohort Of Combination Antiretroviral Therapy Treated People Living With Hiv, Quan Zhang, Xiaoming Li Ph.D., Shan Qiao Ph.D., Shuaifeng Liu, Yuejiao Zhou, Zhiyong Shen

Faculty Publications

Background

Existing literature mostly investigated the relationship of acute or short-term glucocorticoid exposure to HIV disease progression using cortisol levels in serum, saliva, or urine. Data are limited on the relationship of long-term glucocorticoid exposure to HIV disease progression. This study examined whether hair glucocorticoid levels, novel retrospective indicators of long-term glucocorticoid exposure, are associated with two common indicators of HIV disease progression (CD4 count and HIV viral load) among a large cohort of combination antiretroviral therapy treated Chinese people living with HIV (PLHIV).

Methods

A total of 1198 treated PLHIV provided hair samples for glucocorticoid (cortisol and cortisone) assay …

The Who Global Tuberculosis 2021 Report - Not So Good News And Turning The Tide Back To End Tb, Chakaya Jeremiah, Eskild Petersen, Rebecca Nantanda, Brenda N. Mungai, Giovanni Battista Migliori, Farhana Amanullah, Patrick Lungu, Francine Ntoumi, Nagalingeswaran Kumarasamy

Department of Paediatrics and Child Health

Objective: To review the data presented in the 2021 WHO global TB report and discuss the current constraints in the global response.
Introduction and methods: The WHO global TB reports, consolidate TB data from countries and provide up to date assessment of the global TB epidemic. We reviewed the data presented in the 2021 report.
Results: We noted that the 2021 WHO global TB report presents a rather grim picture on the trajectory of the global epidemic of TB including a stagnation in the annual decline in TB incidence, a decline in TB notifications and an increase in estimated TB …

Designing A Fulfilling Life In The Law, Bridgette Carr, Vivek Sankaran, Taylor J. Wilson

Journal of Legal Education

No abstract provided.

Book Review Of The Law Student’S Guide To Doing Well And Being Well, Lawrence Krieger

Journal of Legal Education

No abstract provided.

Exploring The Inferiority Model In Adlerian Psychotherapy, Rachel Bradley

Student Works

Alfred Adler once afflicted with inferiority due to organ inferiority, became the founding father of Individual/Adlerian psychology. Adlerian psychotherapy spans numerous contemporary theories in psychology. Adlerian psychotherapy is a holistic, phenomenological, optimistic and socially entrenched theory, on how everyone interprets themselves and others within the society they live (Maniacci & Sackett-Maniacci, 2019). An overview will be provided of where one of Adler’s most important assumptions, inferiority, fits within the Adlerian theory. Given such, the negative responses to inferiority: inferiority complex and superiority complex will be discussed, followed by socially useful type of inferiority. After that, inferiority as a specific element …

Tangential Cranial Gunshot Wound In An Infant In Historical Context: Illustrative Case, Jeffrey Campbell, Joseph Piatt

Department of Pediatrics Faculty Papers

BACKGROUND

Military neurosurgeons have long known that tangential cranial gunshot wounds can be associated with intracranial complications out of proportion to the external appearance of the injury. This phenomenon seems not to have been described in infancy.

OBSERVATIONS

An infant suffered a massive, acute subdural hemorrhage from a contralateral tangential gunshot wound that did not facture the skull.

LESSONS

Similar to adults, infants are subject to catastrophic intracranial injury from gunshots that do not penetrate the skull. The nature of the injury in this case reflected distinctive aspects of the tissue characteristics and proportions of the infant head.

Increased Risk Of Major Depressive Disorder Following Tinnitus: A Population-Based Study, Herng-Ching Lin, Sudha Xirasagar Mbbs, Ph.D., Chia-Hui Wang, Yen-Fu Cheng, Tzong-Hann Yang

Faculty Publications

Background and Purpose: In this study, we aimed to evaluate the relationship between tinnitus and a subsequent diagnosis of major depressive disorder (MDD) by studying the incidence of both entities.

Design: A retrospective cohort study.

Methods: Data for this observational follow-up study were retrieved from the Taiwan's National Health Insurance Dataset. A total of 375,272 patients with newly diagnosed tinnitus (study group) were retrieved. The date of first diagnosis of tinnitus was assigned as their index date. Comparison patients were selected by propensity score matching (one per case, n = 375,272 controls) from the same dataset, with their index date …

Nurse-Driven Protocols For Abdominal Pain In The Emergency Department, Chris Schmidt

Student Scholarly Projects

Practice Problem: Emergency department (ED) crowding hinders the opportunity to deliver safe, quality care to abdominal pain patients and detrimentally affects clinical outcomes. Leadership of a rural community ED recognized a comparable issue by introducing a nurse-driven protocol (NDP) to reduce patient length of stay (LOS) and the rate of patients who leave the department prior to physician evaluation.

PICOT: The PICOT question that guided this project was: For adult patients in an emergency department, how does a nurse-driven protocol for abdominal pain compared to no protocol use affect the LOS and left without being seen (LWBS) rate over 10 …

Prevention Of Central Line-Associated Blood Stream Infection (Clabsi) In Adult Icu Patients, Salima Allahbachayo

Student Scholarly Projects

Practice Problem: Central line-associated bloodstream infections (CLABSI) account for most hospital-associated preventable infections in the United States and globally. Implementation of a multifaceted approach including evidence-based CLABSI bundle care has shown to prevent this infection in patients with a central line.

PICOT: The PICOT question that guided this project was that in adult intensive care unit (ICU) patients, how does the use of central line bundle care compared to central line care without bundle decrease central line-associated bloodstream infections within eight weeks?

Evidence: The evidence from a rigorous literature review showed that using a central line bundle …

You’Re Testing My Patients: Clinicians’ Preferences For Structured Reporting And Measurement Data, Davit Meliksetyan, Allan Brazier, Adela Pouzar, Sayf Al-Katib

Conference Presentation Abstracts

No abstract provided.

Association Between Serum Lycopene And Lung Cancer Mortality: An 18-Year Follow-Up Study Of A National Cohort, Evans Afriyie-Gyawu, Padmini Shankar, Gulzar H. Shah, Alicia A. Brown, Shannon Cearley, Akwasi Ampofo-Yeboah, Nathaniel Abrams, Jian Zhang

Health Policy & Community Health: Faculty Publications

Background: Lycopene is a carotenoid found in some fruits and vegetables that is responsible for the red pigment in tomatoes and tomato products. While many studies have shown a link between lycopene and protection against the initiation and/or progression of lung cancer, data on its effect on lung cancer survivability is limited.

Objective: The primary objective of this study was to see if there was a link between lycopene levels in the blood and lung cancer mortality. A secondary goal was to see if dietary factors influence lycopene levels in the blood.

Materials and Methods: A retrospective …

A Field Study In An Urban Area: Examining Distracted Pedestrian Unsafe Crossing Behavior, Emma Hood

Undergraduate Research Symposium

A field study examining distracted pedestrian unsafe crossing behavior in an urban area. The study is among the first to contribute knowledge to environmental alterations impact on crossing behavior. Portions of the abstract are a part of a manuscript that will be submitted to Psi Chi Journal of Psychological Research for undergraduate students.

Pharmacologic Ascorbic Acid As Early Therapy For Hospitalized Patients With Covid-19: A Randomized Clinical Trial, Dagan Coppock, Pierre-Christian Violet, Gustavo Vasquez, Katherine Belden, Michael Foster, Bret Mullin, Devon Magee, Isabelle Mikell, Lokesh Shah, Victoria Powers, Brian Curcio, Daniel A. Monti, Mark Levine

Department of Pharmacology and Experimental Therapeutics Faculty Papers

Despite the widespread availability of effective vaccines, new cases of infection with severe acute respiratory syndrome coronavirus-2, the cause of coronavirus disease 2019 (COVID-19), remain a concern in the settings of vaccine hesitancy and vaccine breakthrough. In this randomized, controlled, phase 2 trial, we hypothesized that high-dose ascorbic acid delivered intravenously to achieve pharmacologic concentrations may target the high viral phase of COVID-19 and thus improve early clinical outcomes. Sixty-six patients admitted with COVID-19 and requiring supplemental oxygen were randomized to receive either escalating doses of intravenous ascorbic acid plus standard of care or standard of care alone. The demographic …

Television Viewing Time And All-Cause Mortality: Interactions With Bmi, Physical Activity, Smoking, And Dietary Factors, Christopher T. Swain, Julie K. Bassett, Allison M. Hodge, David W. Dunstan, Neville Owen, Yi Yang, Harindra Jayasekara, James R. Hébert Scd, Nitin Shivappa Mbbs, Mph, Ph.D., Robert J. Macinnis, Roger L. Milne, Dallas R. English, Brigid M. Lynch

Faculty Publications

Background Higher levels of time spent sitting (sedentary behavior) contribute to adverse health outcomes, including earlier death. This effect may be modified by other lifestyle factors. We examined the association of television viewing (TV), a common leisure-time sedentary behavior, with all-cause mortality, and whether this is modified by body mass index (BMI), physical activity, smoking, alcohol intake, soft drink consumption, or diet-associated inflammation. Methods Using data from participants in the Melbourne Collaborative Cohort Study, flexible parametric survival models assessed the time-dependent association of self-reported TV time (three categories: < 2 h/day, 2-3 h/day, > 3 h/day) with all-cause mortality. Interaction terms were fitted to test whether …

Mechanism Of Injury And Special Considerations As Predictive Of Serious Injury: A Systematic Review., Joshua R. Lupton, Cynthia Davis-O'Reilly, Rebecca M. Jungbauer, Craig D. Newgard, Mary E. Fallat, Joshus B. Brown, N. Clay Mann, Gregory J. Jurkovich, Eileen Bulger, Mark L. Gestring, E. Brooke Lerner, Roger Chou, Annette M. Totten

Faculty and Staff Scholarship

Objectives: The Centers for Disease Control and Prevention's field triage guidelines (FTG) are routinely used by emergency medical services personnel for triaging injured patients. The most recent (2011) FTG contains physiologic, anatomic, mechanism, and special consideration steps. Our objective was to systematically review the criteria in the mechanism and special consideration steps that might be predictive of serious injury or need for a trauma center. Methods: We conducted a systematic review of the predictive utility of mechanism and special consideration criteria for predicting serious injury. A research librarian searched in Ovid Medline, EMBASE, and the Cochrane databases for studies published …

68-Year Old Man With Progressive Weakness And Ventilator Dependent Respiratory Failure: A Case Report Of Sporadic Late Onset Nemaline Myopathy, P. Kirupaharan, Daniel Kramer, Alan Gandler, Lawrence C. Kenyon, Ross Summer

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Background: Neuromuscular pathologies must be considered when caring for patients with persistent or progressive respiratory failure. Pertinent disease states may involve skeletal muscles of respiration or associated neurologic structures including motor neurons, peripheral neurons and the neuromuscular junction. Diagnosis may require pulmonary function testing, neurophysiologic studies, imaging, and/or muscle biopsy.

Case presentation: A 68-year-old male was transferred to our intensive care unit (ICU) for management of ventilator dependent respiratory failure. Upon further historical review, he described gradually worsening gait instability and muscle weakness, which was previously attributed to vascular Parkinsonism in the setting of known cerebrovascular disease. Upon arrival to …

Criteria Of Initial Selection Of Candidates For Artistic Gymnastics, Kazimierz Kochanowicz, Andrzej Kochanowicz

Baltic Journal of Health and Physical Activity

Background: The effectiveness of the training process and the level of sports results largely depend on the selection of candidates with appropriate psycho-physical predispositions and the efficiency of the training system. Therefore, selection for artistic gymnastics must be based on coaches' thorough knowledge regarding physical development, interdependence of particular systems and analysers, motor skills and mental determinants. The aim of the study was to develop quantitative criteria of initial selection of candidates for artistic gymnastics. Material/Methods: The study material comprised 319 boys aged 6 qualified for gymnastic training at the Interschool Sports Club and the Academic Sports Association of the …

An Attempt At The Identification Of Anthropometric Conditioning Of Sport Results In 400-Metre Men’S Hurdles, Jakub Adamczyk, Marcin Siewierski, Dariusz Boguszewski

Baltic Journal of Health and Physical Activity

Background: The purpose of this work is to verify the opinions concerning the preferred somatic build and to define current parameters of the model of the sportsmaster in 400-metre hurdles. Material/Methods: Data about the height and the body mass of the best world competitors in 400-metre hurdles have been used in the research. Results were divided into three levels: below 48 s; 48.00–48.99 s and 49.00–49.99 s. For all groups the following indexes were defined: Rohrer’s, Quetelet I and Quetelet II. The dependence between the sports level and the somatic parameters were rated by means of the coefficient of Pearson’s …

An Application Of Incremental Running Test Results To Train Professional Soccer Players, Lukasz Radziminski, Pawel Rompa, Robert Dargiewicz, Wojciech Ignatiuk, Zbigniew Jastrzebski

Baltic Journal of Health and Physical Activity

Background: The aim of this study was to lay out an incremental running test to determine anaerobic threshold and its usefulness as a predictability factor of the physiological load on professional soccer players during soccer training activities. Material/Methods: Subjects performed multi-stage incremental running test at three time points throughout the soccer season on a synthetic soccer pitch to determine the lactate threshold. The initial speed was set at 2.8 m/s and increased by 0.4 m/s after each stage until termination. HR was recorded at 5-second intervals by the Polar heart rate monitor (Polar Electro, FIN) at the end of each …

Relations Between Bioelectrical Muscles Activity And Isokinetic Strength Parameters In 17–19-Year-Old Judoists, Marcin Dornowski

Baltic Journal of Health and Physical Activity

Background: Muscle strength as an element of preparation and sport competition is one of the most important aspects in technical and tactical efficiency. The aim of this study was to define the level of relation between bioelectrical muscle activity and isokinetic strength parameters in 17–19-year-old judoists. Material/Methods: 30 judo athletes (17–19-year-old) took part in the research. The research was conducted in Gdańsk Academy of Physical Education and Sport Laboratory during 2006–2008. In the research authors used: to evaluate the isokinetic strength level, ”Concept 2 Dyno” device was used in the research, along with surface summary electrical bio-potentials reading on EMG …

Junior High School Pupils’ Opinions On The Content And Conduct Of Swimming Classes At School, Grzegorz Bielec

Baltic Journal of Health and Physical Activity

Background: The aim of the study was to recognize high school pupils’ opinions about the content of swimming classes, conducted within obligatory physical education lessons. Material/Methods: The experimental group consisted of 56 girls and 60 boys at the age of 14 (± 0.3). All of them were students of the second grade of public secondary schools. The fourth lesson of their obligatory physical education syllabus was conducted at the swimming pool. An anonymous survey was used as a tool. The survey questions referred to the quality and quantity of swimming exercises at the lesson as well as to methodological skills …

Effects Of Interval Training Of Maximal Effort Intensity, Henryk Norkowski, Anna Kuder, Tadeusz Hucinski, Stanislaw Przybylski

Baltic Journal of Health and Physical Activity

Background: The purpose of this study was to determine changes in anaerobic capacity at 100% physical effort intensity in the examined people. Material/Methods: 12 male students from the University of Physical Education in Warsaw were subject to these examinations. The average age was 23.6 years, mean body height 178.7 cm, and body mass 80.6 kg. The experiment was carried out from 7th January to 8th March 2008. The experiment (one group) was carried out in two stages. The first stage had 25 training units on a cycloergometer within 5 weeks. The second stage was connected with controlling the obtained results …

Individualities Of Cardiorespiratory Responsiveness To Shifts In Respiratory Homeostasis And Physical Exercise In Homogeneous Groups Of High Performance Athletes, Viktor Mishchenko, Oksana Shynkaruk, Andrzej Suchanowski, Olena Lysenko, Tomasz Tomiak, Andrej Diachenko, Adam Korol

Baltic Journal of Health and Physical Activity

Background: It is known that high sports performances are based upon optimization of adaptation process. In order to achieve the above, one should provide a maximal account of individual vivid features of athlete's abilities, peculiarities of his/her physiological reactivity. The aim was to study individualities of sensitivity to shifts in respiratory homeostasis and responsiveness to high intensity physical exercises in homogeneous groups of high performance endurance athletes. Material/Methods: Individual peculiarities of the cardiorespiratory system (CRS) physiological reactivity were evaluated in 118 high performance endurance athletes (cyclists, runners and rowers) aged 20-27 years (competing regularly in sports for 6.8 ± 1.1 …

Cardiorespiratory Responses To Submaximal Exercise In 16-18-Year-Old Trained And Untrained Boys, Marcin Luszczyk, Ewa Ziemann, Tomasz Grzywacz, Radoslaw Laskowski, Anna Szczesna-Kaczmarek

Baltic Journal of Health and Physical Activity

Background: The aim of this study was to compare chosen parameters and coefficients characterizing the action of the cardiovascular system and the respiratory system at a low level of a cycloergometric exercise in young boys practicing handball and their untrained peers. In the present study we searched for an answer to questions concerning the influence of physical training on children’s organism in progressive youth development. Material/Methods: The technique of parallel groups was used: the experimental one (boys training handball, n=12) and the control one (not trained boys, n=58). The developmental age of the subjects was evaluated by percentile charts. A …

Integrating Psychedelic Experiences Through Touch, James Salomons

Journal of Transformative Touch

No abstract provided.

Digital Burnout And Perceptive Failure: The Example Of Physical Education Teachers During The Covid-19 Pandemic, Tayfun Şi̇ri̇n, Yeliz Eratli Şi̇ri̇n, Berna Can, Oğuzkaan Uruç

Baltic Journal of Health and Physical Activity

This research was conducted to examine physical education teachers’ levels of digital burnout and perceptual fatigue during the COVID-19 pandemic. Material and methods: This study was designed according to the quantitative research model and conducted within the framework of the relational screening model. The research group consists of 504 physical education teachers, including 240 women and 264 men, who work in high schools and secondary schools in Adana and Mersin provinces. Results: The results showed that the teachers working in high schools were in the digital environment too much. At the same time, teachers stated that they did not feel …