Medicine and Health Sciences Commons^™

Otolaryngology Subspecialty Surgical Rescheduling Rates During The Covid-19 Pandemic, Emily S Sagalow, Alexander Duffy, Priyanga Selvakumar, David Cognetti

Department of Otolaryngology - Head and Neck Surgery Faculty Papers

Objective: In the beginning of the COVID-19 pandemic in spring 2020, elective and oncologic surgical cases were cancelled. After adequate safety protocols were established, each subspecialty within otolaryngology faced unique challenges in reengaging patients for surgical scheduling.

Study design: Retrospective review from March to May 2020.

Setting: Single academic institution.

Methods: Patients whose otolaryngology surgery was cancelled due to COVID-19 hospital precautions were identified. Rescheduling rates were analyzed by subspecialty. Case completion was determined as the percentage of initially cancelled cases that were completed within 6 months of their original planned dates.

Results: Of 833 otolaryngology cases scheduled between March …

Student Wellness Using A Lifestyle Medicine Approach For Self, Classmates, Patients And Communities, Betsy J. Becker, Teresa Cochran, Tessa Wells, Nicole M. Sleddens, Kathleen G. Volkman

Innovations in Health Sciences Education Journal

This is a published abstract from the UNMC Spotlight on Scholarship 2022.

Phm Triage Curriculum Enhances Residents' Skills And Comfort Of Leading Triage Calls, Sheridan Jost, Jason Burrows, Michelle Howell Smith

Innovations in Health Sciences Education Journal

This is a published abstract from the UNMC Spotlight on Scholarship 2022.

The Effects Of A Clinician Educator Community Of Practice On Wellness Of Internal Medicine Graduate Medical Trainees, Cory Rohlfsen, Michelle Howell Smith

Innovations in Health Sciences Education Journal

This is a published abstract from the UNMC Spotlight on Scholarship 2022.

Immersing Healthcare Students In The Patient Experience Can Improve Diabetes Attitudes And Increase Empathy, Jana L. Wardian Phd, Jannelle Reynolds, Leah M. Stade, Tessa Wells

Innovations in Health Sciences Education Journal

This is a published abstract from the UNMC Spotlight on Scholarship 2022.

Teaching Physicists Effective Patient Communication Through Elearning, Megan Hyun, Kyle J. Gallagher, Sam Hendley, Diane Schott, Sarah Wisnoskie, Dandan Zheng

Innovations in Health Sciences Education Journal

This is a published abstract from the UNMC Spotlight on Scholarship 2022.

Infection Prevention And Control (Ipc) Education Using Xr (Mixed Reality) For Small And Rural Healthcare Facilities, Morgan Shradar, Tess Mckinney, Jody Scebold, Lauren Hinkle, Angela Vasa

Innovations in Health Sciences Education Journal

This is a published abstract from the UNMC Spotlight on Scholarship 2022.

Computationally Driven Discovery Of Sars-Cov-2 M Pro Inhibitors: From Design To Experimental Validation, Léa El Khoury, Jay W Ponder, Et Al

2020-Current year OA Pubs

We report a fast-track computationally driven discovery of new SARS-CoV-2 main protease (M

Immersive Virtual Reality Simulation For Undergraduate Nursing, Beth Culross, Sue A. Schuelke, Krystal Davis

Innovations in Health Sciences Education Journal

This is a published abstract from the UNMC Spotlight on Scholarship 2022.

Integrating A Pharmacist Skills Summit Into A Pharmacotherapy Laboratory Course, Drew Prescott, Kristen Cook

Innovations in Health Sciences Education Journal

This is a published abstract from the UNMC Spotlight on Scholarship 2022.

Development And Validation Of The Pediatric Ethics And Professionalism Assessment Tool (Pedi-Epat), David Soffer, Lori Newman, Mary Brennan, David Williams, Christy Cummings

Innovations in Health Sciences Education Journal

This is a published abstract from the UNMC Spotlight on Scholarship 2022.

Evaluating Medical Student Confidence And Competency Related To Dermatologic Morphology And The Effect Of An Educational Module And Summary Document, Grant Starkey, Megan Arthur

Innovations in Health Sciences Education Journal

This is a published abstract from the UNMC Spotlight on Scholarship 2022.

Creating An E-Learning Module: Reality Of Children Experiencing Social Determinants Of Health, Jana L. Wardian Phd, Leah M. Stade

Innovations in Health Sciences Education Journal

This is a published abstract from the UNMC Spotlight on Scholarship 2022.

Bruxism Oral Appliances: A Guide By Students For Students, Julie Marshall

Innovations in Health Sciences Education Journal

This is a published abstract from the UNMC Spotlight on Scholarship 2022.

Psychometrics And The Future Of The Critical Thinking Self-Assessment Scale, Lynnette Stamler Dr., Louise Laframboise, Teresa Barry Hultquist, Kevin A. Kupzyk

Innovations in Health Sciences Education Journal

This is a published abstract from the UNMC Spotlight on Scholarship 2022.

Lecture, Online, Flipped, And Blended: A Mixed Methods Study On Sonography Student Outcomes & Perceptions, Tanya M. Custer, Kim Michael, Kathryn Wampler, Lea Lambing

Innovations in Health Sciences Education Journal

This is a published abstract from the UNMC Spotlight on Scholarship 2022.

Effectiveness Of A Hybrid Social Determinants Of Health Experience, Aleisha Nabower, Melanie Menning, Susan Evans, Nathaniel Goodrich, Jenenne A. Geske, Jennifer Liu

Innovations in Health Sciences Education Journal

This is a published abstract from the UNMC Spotlight on Scholarship 2022.

A Standardized Diagnostic Pathway For Suspected Appendicitis In Children Reduces Unnecessary Imaging, Roshan J. D'Cruz, Allison F. Linden, Courtney L. Devon, Jillian Savage, Arezoo Zomorrodi, Kirk W. Reichard, Arabinda Choudhary, Loren Berman

Department of Surgery Faculty Papers

Introduction:

Ultrasound (US) for the diagnosis of acute appendicitis is often nondiagnostic, and additional imaging is required. A standardized approach may reduce unnecessary imaging.

Methods:

We retrospectively analyzed all patients who had imaging for appendicitis in our emergency department in 2017 and evaluated patient characteristics associated with nondiagnostic US. Using these results, we developed a pediatric appendicitis score (PAS)-based imaging pathway and compared imaging trends prepathway and postpathway implementation.

Results:

A total of 971 patients received imaging for suspected appendicitis prepathway in 2017. Female sex, obesity, and low/intermediate PAS were significantly associated with nondiagnostic US, but not magnetic resonance imaging …

Tick Surveillance And Pathogen Detection In Eastern South Dakota, Holly E. Black

Honors Thesis

Tick-borne diseases threaten the health of humans, animals, and ecosystems, but surveillance efforts are lacking in some regions. Throughout 2019, 2020, and 2021, we conducted tick surveys aimed at determining the status of the black-legged tick (Ixodes scapularis), the American dog tick (Dermacentor variabilis) and the lone star tick (Amblyoma americanum) in eastern South Dakota. Each year, ticks were collected using a flagging method and identified in the lab. A subset were tested for the presence of Borrelia burgdorferi, the causative agent of Lyme disease, by polymerase chain reaction (PCR). Dermacentor variabilis was the most commonly identified tick, …

Tell Me More: Parent–Child Sexual Talk And Young Adult Sexual Communication Satisfaction With Romantic Partners, Kelsi N. Wilson, Jakob Jensen, Sharon Ballard, Alan Taylor

Journal of Social, Behavioral, and Health Sciences

Young adults (18–30) tend to show insufficient levels of communication about sex with their romantic partners, despite its many benefits to relationships among this age group. Learned sexual shame and guilt can play a role in inhibiting sexual communication with partners, and early messages about sex from parents stemming from narrow cultural boundaries of communication may play a role in fostering sexual shame and guilt from a young age, potentially influencing later sexual communication patterns with partners. We sought to identify whether a significant relationship existed between the sexual communication participants received from parents while growing up and their current …

Efficacy Of Tuberculosis Vaccine Candidate Pcdna3.1-Rpfb In Inhibiting The Growth Of Mycobacterium Tuberculosis In Vitro With Mycobacterial Growth Inhibition Assay, Ratih Pujilestari, Andriansjah Rukmana, Anis Karuniawati

Makara Journal of Science

Tuberculosis (TB) is caused by Mycobacterium tuberculosis (Mtb). Bacille Calmette-Guérin (BCG) is the only licensed vaccine against TB, and it is effective in children but not in adults. The Vaccine Research Team, Department of Microbiology FKUI has developed a DNA-based TB vaccine candidate pcDNA3.1-rpfB. This candidate induces immune responses in mice, but its potency is unknown. The gold standard for potency testing of TB vaccine is the challenge method. The BSL3 animal laboratory for the challenge method is currently unavailable at FKUI. Therefore, mycobacterial growth inhibition assay (MGIA) was used as a preliminary test before the in vivo …

Evaluation Of Nitrite Concentration In Edible Bird’S Nest (White, Yellow, Orange, And Red Blood), Siti Gusti Ningrum, Bagus Uda Palgunad, Rochiman Sasmita

Makara Journal of Science

The color of edible bird’s nest is associated with its nitrite concentration, but this relationship remains inconclusive. This investigation aimed to evaluate the nitrite content in edible bird’s nest of four different colors: white, yellow, orange, and red blood. Fifty-eight edible bird’s nest samples were obtained from five swiftlet farmhouses in Borneo Island, Indonesia and analyzed for nitrite content using Genesys 30 visible spectrophotometer. Results showed that the dark-colored edible bird’s nests (yellow, orange, and red blood) had higher nitrite concentrations of 304, 317, and 309 ppm, respectively, compared with the white-colored one (15 ppm). Therefore, the color of edible …

Mutations Of The Dna Repair Gene Pnkp In A Patient With Microcephaly, Seizures, And Developmental Delay (Mcsz) Presenting With A High-Grade Brain Tumor, Bingcheng Jiang, Cameron Murray, Bonnie L Cole, J N Mark Glover, Gordon K Chan, Jean Deschenes, Rajam S Mani, Sudip Subedi, John D Nerva, Anthony C Wang, Christina M Lockwood, Heather C Mefford, Sarah E S Leary, Jeffery G Ojemann, Michael Weinfeld, Chibawanye I Ene

Faculty, Staff and Student Publications

Polynucleotide Kinase-Phosphatase (PNKP) is a bifunctional enzyme that possesses both DNA 3'-phosphatase and DNA 5'-kinase activities, which are required for processing termini of single- and double-strand breaks generated by reactive oxygen species (ROS), ionizing radiation and topoisomerase I poisons. Even though PNKP is central to DNA repair, there have been no reports linking PNKP mutations in a Microcephaly, Seizures, and Developmental Delay (MSCZ) patient to cancer. Here, we characterized the biochemical significance of 2 germ-line point mutations in the PNKP gene of a 3-year old male with MSCZ who presented with a high-grade brain tumor (glioblastoma multiforme) within the cerebellum. …

An Investigation Of A Novel Broad Autism Phenotype: Increased Facial Masculinity Among Parents Of Children On The Autism Spectrum, Diana Weiting Tan, Syed Zulqarnain Gilani, Gail A. Alvares, Ajmal Mian, Andrew J. O. Whitehouse, Murray T. Maybery

Research outputs 2022 to 2026

The broad autism phenotype commonly refers to sub-clinical levels of autistic-like behaviour and cognition presented in biological relatives of autistic people. In a recent study, we reported findings suggesting that the broad autism phenotype may also be expressed in facial morphology, specifically increased facial masculinity. Increased facial masculinity has been reported among autistic children, as well as their non-autistic siblings. The present study builds on our previous findings by investigating the presence of increased facial masculinity among non-autistic parents of autistic children. Using a previously established method, a 'facial masculinity score' and several facial distances were calculated for each three-dimensional …

Geotemporospatial And Causal Inferential Epidemiological Overview And Survey Of Usa Cannabis, Cannabidiol And Cannabinoid Genotoxicity Expressed In Cancer Incidence 2003–2017: Part 2 – Categorical Bivariate Analysis And Attributable Fractions, Albert Stuart Reece, Gary Kenneth Hulse

Research outputs 2022 to 2026

Background: As the cannabis-cancer relationship remains an important open question epidemiological investigation is warranted to calculate key metrics including Rate Ratios (RR), Attributable Fractions in the Exposed (AFE) and Population Attributable Risks (PAR) to directly compare the implicated case burden between emerging cannabinoids and the established carcinogen tobacco. Methods: SEER*Stat software from Centres for Disease Control was used to access age-standardized state census incidence of 28 cancer types (including “All (non-skin) Cancer”) from National Cancer Institute in US states 2001–2017. Drug exposures taken from the National Survey of Drug Use and Health 2003–2017, response rate 74.1%. Federal seizure data provided …

Geotemporospatial And Causal Inferential Epidemiological Overview And Survey Of Usa Cannabis, Cannabidiol And Cannabinoid Genotoxicity Expressed In Cancer Incidence 2003–2017: Part 3 – Spatiotemporal, Multivariable And Causal Inferential Pathfinding And Exploratory Analyses Of Prostate And Ovarian Cancers, Albert Stuart Reece, Gary Kenneth Hulse

Research outputs 2022 to 2026

Background: The epidemiology of cannabinoid-related cancerogenesis has not been studied with cutting edge epidemiological techniques. Building on earlier bivariate papers in this series we aimed to conduct pathfinding studies to address this gap in two tumours of the reproductive tract, prostate and ovarian cancer. Methods: Age-standardized cancer incidence data for 28 tumour types (including “All (non-skin) Cancer”) was sourced from Centres for Disease Control and National Cancer Institute using SEER*Stat software across US states 2001–2017. Drug exposure was sourced from the nationally representative household survey National Survey of Drug Use and Health conducted annually by the Substance Abuse and Mental …

Geotemporospatial And Causal Inferential Epidemiological Overview And Survey Of Usa Cannabis, Cannabidiol And Cannabinoid Genotoxicity Expressed In Cancer Incidence 2003–2017: Part 1 - Continuous Bivariate Analysis, Albert Stuart Reece, Gary Kenneth Hulse

Research outputs 2022 to 2026

Background

The genotoxic and cancerogenic impacts of population-wide cannabinoid exposure remains an open but highly salient question. The present report examines these issues from a continuous bivariate perspective with subsequent reports continuing categorical and detailed analyses.

Methods

Age-standardized state census incidence of 28 cancer types (including “All (non-skin) Cancer”) was sourced using SEER*Stat software from Centres for Disease Control and National Cancer Institute across US states 2001–2017. It was joined with drug exposure data from the nationally representative National Survey of Drug Use and Health conducted annually by the Substance Abuse and Mental Health Services Administration 2003–2017, response rate 74.1%. …

College Students’ Perceptions Of Anxiety And Coping: Physical Activity Versus Alcohol Use, John M. Neville

Honors College Theses

Anxiety is likely to impact every single person in the world. It can, at times, be advantageous; however, at other times, it can be crippling. There is not a consensus as to its cause. But, through years of research it has been discovered it results from structural and chemical changes within the brain. It is believed these changes contribute largely to the development of anxiety. Other factors such as stressors, trauma, and substance abuse may exacerbate anxiety and accelerate its development. This has prompted researchers, scientists, and clinicians to explore ways in which individuals may cope with this condition. For …

Establishment Of A Melanoma Esc-Gemm Platform And Its Use To Study Pten Tumor Suppressor Functions, Ilah Bok

USF Tampa Graduate Theses and Dissertations

The cumbersome and time-consuming process of generating new mouse strains and multiallelic experimental animals often hinders the use of genetically engineered mouse models (GEMM) in cancer research. In chapter 2, we describe the development and validation of an embryonic stem cell (ESC)-GEMM platform for rapid modeling of melanoma in mice. The platform incorporates 12 clinically relevant genotypes composed of combinations of four driver alleles (LSL-BrafV600E, LSL-NrasQ61R, PtenFlox, and Cdkn2aFlox) and regulatory alleles to spatiotemporally control the perturbation of genes of interest. The ESCs produce high-contribution chimeras, which recapitulate the melanoma phenotypes of conventionally bred mice. Using the ESC-GEMM platform to …

Cistrome And Transcriptome Analysis Identifies Unique Androgen Receptor (Ar) And Ar-V7 Splice Variant Chromatin Binding And Transcriptional Activities, Paul Basil, Matthew J Robertson, William E Bingman, Amit K Dash, William C Krause, Ayesha A Shafi, Badrajee Piyarathna, Cristian Coarfa, Nancy L Weigel

Faculty, Staff and Students Publications

The constitutively active androgen receptor (AR) splice variant, AR-V7, plays an important role in resistance to androgen deprivation therapy in castration resistant prostate cancer (CRPC). Studies seeking to determine whether AR-V7 is a partial mimic of the AR, or also has unique activities, and whether the AR-V7 cistrome contains unique binding sites have yielded conflicting results. One limitation in many studies has been the low level of AR variant compared to AR. Here, LNCaP and VCaP cell lines in which AR-V7 expression can be induced to match the level of AR, were used to compare the activities of AR and …