Medicine and Health Sciences Commons^™

How Occupational Therapists Address Chronic Pain And Sex/Intimacy, Millie Szeto, Susan Macdermott

Spring 2022 Virtual OTD Capstone Symposium

Sexual activity is 1 out of the 9 activities of daily living (ADLs) and is considered to be fundamental for a person's life, yet it is one of the least discussed topics that occupational therapists address in client care settings, academia, and/or professional development.

The aim for this project was to explore how occupational therapists addressed sex/intimacy with the chronic pain population in order to provide more insight and encouragement for other occupational therapists to incorporate discussion of sex/intimacy in their practice.

An Ot-Led Suicide Prevention Program For Middle School-Aged Youth, Kimberly Everett-Eaton, Susan Macdermott, Jazminne Orozco Arteaga

Spring 2022 Virtual OTD Capstone Symposium

Suicide is the fastest-growing cause of death for adolescents ages 10-14 (Horowitz et al., 2020). In the United States, the youth suicide rate tripled from 2007 to 2017, making suicide the second leading cause of death for those ages 10-24 (Curtis, 2019). This prevention program, Brighter Days Collective, utilizes occupational therapy (OT) practitioners to support middle school-aged adolescents by applying OT interventions based on theory and evidence-based practices. Brighter Days Collective aims to utilize OT practitioner expertise to support adolescents through educating students about mental health and employing occupations that enhance connection, coping skills, and living a purposeful life.

This …

Qualitative Evaluation Of Occupational Therapy Assessments In Treating Veterans With Ptsd Who Are Transitioning Into Civilian Life, Natalia Marquez-Sterling, Pam Kasyan-Howe, Kristin Domville, Lisa Schubert

Spring 2022 Virtual OTD Capstone Symposium

The purpose of this qualitative research type capstone project was to explore the strengths and limitations of an occupational therapist assessment toolkit for use with the population of veterans with PTSD who are transitioning into civilian life. OTs lack consistent assessment tools for use with this population, resulting in a lack of inclusion of occupational therapy as a consistent member of the multidisciplinary team (Kerr et al., 2020). Kerr et al. (2020) found that while OT assessments may be mentioned in research regarding veterans with PTSD who are transitioning into civilian life, there was limited or no discussion of the …

Synthesis, Characterization, And In Vivo Cytokinome Profile Of Il-12-Loaded Plga Nanospheres, Ryan A. Lacinski, Justin E. Markel, Jabeen Noore, Hillary G. Pratt, Brock A. Lindsey

Faculty & Staff Scholarship

We report the successful encapsulation and elution of recombinant murine IL-12 (rmIL-12) from poly(lactide-co-glycolic) acid (PLGA) nanospheres (IL-12-NS) synthesized using the double emulsion/solvent evaporation (DESE) technique with microsphere depletion through ultracentrifugation. Images obtained with scanning electron microscopy (SEM) showcased a characteristic spherical shape with a mean particle diameter of and zeta potential of . These values suggest minimal flocculation when in solution, which was reflected in an in vivo biodistribution study that reported no observed morbidity/mortality. Encapsulation efficiency (EE) was determined to be with average particle concentration obtained per batch of particles/mL. Disparate zeta (ζ) potentials obtained from …

Assessment Of Dietary And Lifestyle Responses After Covid-19 Vaccine Availability In Selected Arab Countries, Leila Cheikh Ismail, Tareq M. Osaili, Maysm N. Mohamad, Amina Al Marzouqi, Carla Habib-Mourad, Dima O. Abu Jamous, Habiba I. Ali, Haleama Al Sabbah, Hayder Hasan, Hussein Hassan, Lily Stojanovska, Mona Hashim, Muna Alhaway, Radwan Qasrawi, Reyad R. Shaker Obaid, Rameez Al Daour, Sheima T. Saleh, Ayesha S. Al Dhaheri

All Works

The COVID-19 pandemic has been consistently associated with unhealthy lifestyle behaviors and dietary practices. This study aimed to assess the dietary and lifestyle behaviors of adults after COVID-19 vaccine availability and their attitude toward the vaccine in selected Arab countries. A cross-sectional survey-based study was conducted between October 2021 and December 2021 using Google Forms (n = 2259). A multi-component questionnaire was used to collect socio-demographic characteristics, attitudes toward the COVID-19 vaccine, and behavioral, dietary, and lifestyle responses after easing the restriction. Participants were given a score based on the sum of positive dietary and lifestyle changes. The generalized linear …

Surgery In Advanced Ovary Cancer: Primary Versus Interval Cytoreduction, Mackenzie Cummings, Olivia Nicolais, Mark S. Shahin

Department of Obstetrics and Gynecology Faculty Papers

Primary debulking surgery (PDS) has remained the only treatment of ovarian cancer with survival advantage since its development in the 1970s. However, survival advantage is only observed in patients who are optimally resected. Neoadjuvant chemotherapy (NACT) has emerged as an alternative for patients in whom optimal resection is unlikely and/or patients with comorbidities at high risk for perioperative complications. The purpose of this review is to summarize the evidence to date for PDS and NACT in the treatment of stage III/IV ovarian carcinoma. We systematically searched the PubMed database for relevant articles. Prior to 2010, NACT was reserved for non-surgical …

Sexual Assault: Disclosure, Healthcare Barriers And Facilitators, And Interventions, Meghan Stepnitz

Honors Theses

Sexual assault is apparent across the globe. Sexual assault victims and survivors face many barriers that decrease disclosure to healthcare providers leading to it becoming underreported. These barriers can be alleviated with interventions implemented by healthcare providers to ease the process of disclosure. Victims and survivors also face barriers seeking post-assault, follow-up, and mental healthcare. Researchers have described the barriers that sexual assault victims and survivors face accessing healthcare in the immediate period after assault, but less research has focused on healthcare beyond this period. Recognizing these barriers gives the opportunity for healthcare providers to remove them and make healthcare …

Ancestral Diversity Improves Discovery And Fine-Mapping Of Genetic Loci For Anthropometric Traits–The Hispanic/Latino Anthropometry Consortium, Lindsay Fernández-Rhodes, Mariaelisa Graff, Victoria L Buchanan, Anne E Justice, Heather M Highland, Xiuqing Guo, Wanying Zhu, Hung-Hsin Chen, Kristin L Young, Kaustubh Adhikari, Nicholette D Palmer, Jennifer E Below, Jonathan Bradfield, Alexandre C Pereira, Láshauntá Glover, Daeeun Kim, Adam G Lilly, Poojan Shrestha, Alvin G Thomas, Xinruo Zhang, Minhui Chen, Charleston W K Chiang, Sara Pulit, Andrea Horimoto, Jose E Krieger, Marta Guindo-Martínez, Michael Preuss, Claudia Schumann, Roelof A J Smit, Gabriela Torres-Mejía, Victor Acuña-Alonzo, Gabriel Bedoya, Maria-Cátira Bortolini, Samuel Canizales-Quinteros, Carla Gallo, Rolando González-José, Giovanni Poletti, Francisco Rothhammer, Hakon Hakonarson, Robert Igo, Sharon G Adler, Sudha K Iyengar, Susanne B Nicholas, Stephanie M Gogarten, Carmen R Isasi, George Papnicolaou, Adrienne M Stilp, Qibin Qi, Minjung Kho, Jennifer A Smith, Carl D Langefeld, Lynne Wagenknecht, Roberta Mckean-Cowdin, Xiaoyi Raymond Gao, Darryl Nousome, David V Conti, Ye Feng, Matthew A Allison, Zorayr Arzumanyan, Thomas A Buchanan, Yii-Der Ida Chen, Pauline M Genter, Mark O Goodarzi, Yang Hai, Willa Hsueh, Eli Ipp, Fouad R Kandeel, Kelvin Lam, Xiaohui Li, Jerry L Nadler, Leslie J Raffel, Kathryn Roll, Kevin Sandow, Jingyi Tan, Kent D Taylor, Anny H Xiang, Jie Yao, Astride Audirac-Chalifour, Jose De Jesus Peralta Romero, Fernando Hartwig, Bernando Horta, John Blangero, Joanne E Curran, Ravindranath Duggirala, Donna E Lehman, Sobha Puppala, Laura Fejerman, Esther M John, Carlos Aguilar-Salinas, Noël P Burtt, Jose C Florez, Humberto García-Ortíz, Clicerio González-Villalpando, Josep Mercader, Lorena Orozco, Teresa Tusié-Luna, Estela Blanco, Sheila Gahagan, Nancy J Cox, Craig Hanis, Nancy F Butte, Shelley A Cole, Anthony G Comuzzie, V Saroja Voruganti, Rebecca Rohde, Yujie Wang, Tamar Sofer, Elad Ziv, Struan F A Grant, Andres Ruiz-Linares, Jerome I Rotter, Christopher A Haiman, Esteban J Parra, Miguel Cruz, Ruth J F Loos, Kari E North

Faculty, Staff and Student Publications

Hispanic/Latinos have been underrepresented in genome-wide association studies (GWAS) for anthropometric traits despite their notable anthropometric variability, ancestry proportions, and high burden of growth stunting and overweight/obesity. To address this knowledge gap, we analyzed densely imputed genetic data in a sample of Hispanic/Latino adults to identify and fine-map genetic variants associated with body mass index (BMI), height, and BMI-adjusted waist-to-hip ratio (WHRadjBMI). We conducted a GWAS of 18 studies/consortia as part of the Hispanic/Latino Anthropometry (HISLA) Consortium (stage 1, n = 59,771) and generalized our findings in 9 additional studies (stage 2, n = 10,538). We conducted a trans-ancestral GWAS …

Intake Patterns Of Specific Alcoholic Beverages By Prostate Cancer Status, Hui Yi Lin, Tung-Sung Tseng, Xinnan Wang, Zhide Fang, Arnold H. Zea, Liang Wang, Julio Pow-Sang, Catherine M. Tangen, Phyllis J. Goodman, Alicja Wolk, Niclas Håkansson, Manolis Kogevinas, Javier Llorca, Hermann Brenner, Ben Schöttker, Jose Esteban Castelao, Manuela Gago-Dominguez, Marija Gamulin, Davor Lessel, Frank Claessens, Steven Joniau, Jong Y. Park

School of Public Health Faculty Publications

Background: Previous studies have shown that different alcoholic beverage types impact prostate cancer (PCa) clinical outcomes differently. However, intake patterns of specific alcoholic beverages for PCa status are understudied. The study’s objective is to evaluate intake patterns of total alcohol and the three types of beverage (beer, wine, and spirits) by the PCa risk and aggressiveness status. Method: This is a cross-sectional study using 10,029 men (4676 non-PCa men and 5353 PCa patients) with European ancestry from the PCa consortium. Associations between PCa status and alcohol intake patterns (infrequent, light/moderate, and heavy) were tested using multinomial logistic regressions. Results: Intake …

Boarding Barriers For Psychiatric Patients In Emergency Departments, Emmeline B. Martin Bsn, Rn, Alison Rossano Bsn, Rn, Diana Dedmon Dnp, Aprn, Fnp-Bc

Doctor of Nursing Practice Projects

Objective To identify past or current literature about emergency department holds and psychiatric patients consisting of the evaluation of patient outcomes, satisfaction and equity of care. It is already known that shorter boarding times from the emergency department to a psychiatric unit have positive patient outcomes such as a decrease in readmissions, increase in patient satisfaction and efficiency in appropriate treatment.

Method A scoping review to analyze data by grouping articles into themes which included authors, date of publication, aims/purpose, methodology, sample, interventional details, and the key findings in each article. Excluded articles included those discussing COVID-19 and case management. …

Impact Of Ante- And Postnatal Depression Screening In Women With Hiv: A Scoping Review, Kimberly M. Grider Bsn, Rn, Pmh-Bc, Bao Chau Le Bsn, Rn, Blessing Okon Bsn, Rn, Diana Dedmon Dnp, Aprn, Fnp-Bc

Doctor of Nursing Practice Projects

Purpose/Background Maternal depression has been identified as a strong predictor of poor prenatal care. Among pregnant women living with Human Immunodeficiency Virus (HIV), mental health-related factors such as depression could potentially undermine effective antiretroviral therapy (ART) adherence, increase mortality, and cause poor HIV viral suppression consequently impacting vertical transmission of HIV. This scoping review aims to identify existing knowledge regarding the impact of ante- and postnatal depression screening in women with HIV and to adduce the necessity for effective screening.

Methods A literature search was performed for studies with primary outcomes of depression screening within the context of ante- or …

Convection Enhanced Delivery Of The Oncolytic Adenovirus Delta24-Rgd In Patients With Recurrent Gbm: A Phase I Clinical Trial Including Correlative Studies, Erik H P Van Putten, Anne Kleijn, Victor W Van Beusechem, David Noske, Cor H J Lamers, Anna L De Goede, Sander Idema, Daphna Hoefnagel, Jenneke J Kloezeman, Juan Fueyo, Frederick F Lang, Charlotte E Teunissen, René M Vernhout, Cathy Bakker, Winald Gerritsen, David T Curiel, Arnold Vulto, Martine L M Lamfers, Clemens M F Dirven

Faculty, Staff and Student Publications

Purpose: Testing safety of Delta24-RGD (DNX-2401), an oncolytic adenovirus, locally delivered by convection enhanced delivery (CED) in tumor and surrounding brain of patients with recurrent glioblastoma.

Patients and methods: Dose-escalation phase I study with 3+3 cohorts, dosing 107 to 1 × 1011 viral particles (vp) in 20 patients. Besides clinical parameters, adverse events, and radiologic findings, blood, cerebrospinal fluid (CSF), brain interstitial fluid, and excreta were sampled over time and analyzed for presence of immune response, viral replication, distribution, and shedding.

Results: Of 20 enrolled patients, 19 received the oncolytic adenovirus Delta24-RGD, which was found to be safe and feasible. …

Medical Manikin Augmented Reality Simulation (M2ars), Pauline Delacruz, Jacob Gibson, Daniel Howard, Jaclyn Peacock, Kendall Robbins

Modeling, Simulation and Visualization Student Capstone Conference

The Medical Manikin Augmented Reality Simulation (M2ARS) is an augmented reality simulation application built for the Microsoft HoloLens 2 that uses the principles of anatomy transfer to overlay human anatomical structures onto a medical manikin digitally. These structures currently consist of the skeletal, muscular, and circulatory systems. In addition, a model of the lungs and an animated heart are also available within the simulation. M2ARS allows the user to view these structures in a manner that is both visually and spatially accurate to the human body. This application contains two modes; an augmented reality mode, which uses a manikin, and …

Multi-Modality Breast Mri Segmentation Using Nn-Unet For Preoperative Planning Of Robotic Surgery Navigation, Motaz Alqaoud, John Plemmons Md, Eric Feliberti Md, Facs, Krishnanand Kaipa, Siqin Dong, Gabor Fichtinger, Yimming Xiao, Michel Audette

Modeling, Simulation and Visualization Student Capstone Conference

Segmentation of the chest region and breast tissues is essential for surgery planning and navigation. This paper proposes the foundation for preoperative segmentation based on two cascaded architectures of deep neural networks (DNN) based on the state-of-the-art nnU-Net. Additionally, this study introduces a polyvinyl alcohol cryogel (PVA-C) breast phantom based on the segmentation of the DNN automated approach, enabling the experiments of navigation system for robotic breast surgery. Multi-modality breast MRI datasets of T2W and STIR images were acquired from 10 patients. Segmentation evaluation utilized the Dice Similarity Coefficient (DSC), segmentation accuracy, sensitivity, and specificity. First, a single class labeling …

Cytospin-A Regulates Colorectal Cancer Cell Division And Migration By Modulating Stability Of Microtubules And Actin Filaments, Fan Fan, Jason Roszik, Ling Xia, Susmita Ghosh, Rui Wang, Xiangcang Ye, David Hawke, Lee M Ellis, Rajat Bhattacharya

Faculty, Staff and Student Publications

Simple Summary

In this study, we report the effects of depleting cytospin-A (CYTSA), also known as the sperm antigen with calponin homology and coiled-coil domain (SPECC1L) protein, on the proliferation and migration of colorectal cancer (CRC) cells. Mutations in this protein have been previously linked to different developmental disorders. In our studies, depletion of CYTSA in various CRC cells led to significant decreases in proliferation, increases in cell death, and increased formation of multinucleated cells. Knocking down CYTSA also led to severe inhibition of CRC cell migration and invasion. These effects could be related to a significant decrease in the …

A Photography-Based, Social Media Walking Intervention Targeting Autonomous Motivations For Physical Activity: Semistructured Interviews With Older Women, Michael C Robertson, Maria Chang Swartz, Ursela Christopherson, Jason R Bentley, Karen M Basen-Engquist, Debbe Thompson, Elena Volpi, Elizabeth J Lyons

Faculty, Staff and Students Publications

BACKGROUND: Older adult women are at risk for negative health outcomes that engaging in sustained physical activity can help prevent. However, promoting long-term maintenance of physical activity in this population has proven to be a challenge. Increasing autonomous motivations (ie, intrinsic, integrated, and identified regulations) for physical activity may facilitate enduring behavior change. Digitally delivered games for health that take a celebratory technology approach, that is, using technology to create new ways to experience valued behaviors and express valued beliefs, may be a useful way to target autonomous motivations for physical activity. Formative research with the target population is needed …

Physician's Attitudes On Pulmonary Rehabilitation Following Covid-19: A Brief Perspective From A Developing Country, Ivan Cherrez-Ojeda, Emanuel Vanegas, Miguel Felix, María José Farfán Bajaña, Azza Sarfraz, Zouina Sarfraz, Genesis Camacho, Alanna Barrios-Ruiz, Jack Michel

Department of Paediatrics and Child Health

Despite the uncertainty about the follow up of COVID-19 survivors, there is a growing body of evidence supporting specific interventions including pulmonary rehabilitation, which may lead to a reduced hospital stay and improved overall respiratory function. The aim of this short report was to assess the attitudes toward pulmonary rehabilitation following COVID-19 among Ecuadorian physicians. A cross-sectional study was conducted, in which a 5-question survey was used to assess the level of agreement to specific statements with a 5-point Likert scale. Out of the 282 participants, 48.2% (n=136) were male, with a mean of 12.6 (SD=11.3) years of experience. More …

Surgical Intervention With Adjunctive Cryotherapy For Canine Conjunctival Hemangiosarcomas Versus Hemangiomas, Lisa M. Hoard

Biomedical Engineering ETDs

Conjunctival hemangiomas and hemangiosarcomas are vascular tumors that affect the tissue in the eyes of canines. While relatively rare, these tumors can be costly to remove, and have a possibility of recurrence. Therefore, more understanding of the nature of these tumors and recurrence rates is of importance to the veterinary ophthalmologist. To date, there is limited data in the literature (2 retrospective studies) that examine the development, treatment, and recurrence of these vascular tumors; furthermore, the analyses do not examine the potential recurrence of tumors after treatment with therapies adjunctive to surgery (such as cryoablation, radiotherapy, and others). For this …

Limiting Potentially Inappropriate Medications In Long-Term Care, Clare M. Ironside

Doctor of Nursing Practice Scholarly Projects

Aim: This project aimed to assess the effectiveness of the STOPP/START tool in identifying and reducing potentially inappropriate medications among multi-morbid, older, long-term care residents in a metropolitan area of a Southwestern state.

Design: In this quality improvement project, seven prescribers working within four long-term care facilities were trained to assess for potentially inappropriate medications using the STOPP/START tool. The medication lists for long-term care residents (n =45) over age 65 were collected at baseline and again at three months post-intervention and assessed for overall medication use, psychotropics, and proton pump inhibitors. The project also assessed prescribers’ comfort and …

Prenatal Alcohol Exposure Alters The Expression Of Mir-150-5p And Its Vascular Targets In Brain Microvascular Endothelial Cells And Disrupts The Structure And Integrity Of The Developing Brain Vasculature, Gabriela Perales

Biomedical Sciences ETDs

Prenatal alcohol exposure (PAE) can result in fetal alcohol spectrum disorders (FASD) causing developmental disabilities and neurocognitive deficits. The effects of PAE on neuronal-specific alterations during brain development have been studied extensively but the contribution of the brain vascular system is limited. Recent studies have determined that there are alterations to the cortical microvasculature during PAE, posing new questions about the role of the vasculature and the development of PAE-mediated neurocognitive deficits. Even less studied are the molecular mechanisms that contribute to changes in the vasculature during PAE. As microRNAs (miRNAs) are master post-transcriptional regulators capable of regulating many mRNA …

A New Way Of Learning: Student Revelations From A Sport Development Service-Learning Course, Deondra E. Johnson

Eagle Showcase: Excellence in Service-Learning (Archived)

No abstract provided.

Eta Sigma Gamma - Georgia Southern University Chapter: Breast Cancer Awareness Health Communication Plan, Jill Johns, Omolola Okunromade

Eagle Showcase: Excellence in Service-Learning (Archived)

The health communication plan was used to evaluate public health communication and advocacy promotion by efficiently increasing awareness about breast health and preventive services such as mammography screening among college students and women eligible for breast cancer screening. The communication plan was targeted towards empowering the Georgia Southern University chapter of Eta Sigma Gamma (ESG) members and other college students to act as health advocates by virtually disseminating information through the Facebook platform to their peer groups and social networks including friends and families in their community.

The purposes of the program evaluation and implementation measurement were to: 1) monitor …

Kras Regulation Of Er-Mitochondria Calcium Flux In Colorectal Cancer, Nicholas Hill

Liberty University Research Week

Undergraduate

Basic

Clinical Placement Sites Influence Student Learning And Future Employment An Integrative Literature Review, Jennifer Olmstead

Liberty University Research Week

Graduate

Theoretical Proposal

Faculty Experiences In Simulation Debriefing In Nurse Practitioner Programs, Jodi Duncan

Liberty University Research Week

Doctoral

Theoretical Proposal

Addressing Obesity: A Call For Church Involvment, Katherine Riley, Julia Remelgado

Liberty University Research Week

Undergraduate

Theoretical Proposal

Male Sexual Violence: Prevalence And Consequences Of This Underreported Social Evil, Leslie Knight

Liberty University Research Week

Undergraduate

Theoretical Proposal

The Affects Of Dementia On Signed Language Production For D/Deaf Clients Communicating With Sign Language Interpreters, Alayna Wade

Liberty University Research Week

Undergraduate

Theoretical Proposal

Using Natural Antimicrobials With Pandas Disorder, Michelle Tonkin

Liberty University Research Week

Undergraduate

Theoretical Proposal

Is An Ounce Of Simulation Worthy A Pound Of Safety? Impact Of Safety-Focused Simulation On Medication Errors And Failure To Rescue Events: A Review, Kathy Miller

Liberty University Research Week

Graduate

Theoretical Proposal