Medicine and Health Sciences Commons^™

Our Early Years Of Life's Effects On Our Future Health And Well-Being, Claudia Gagliano

Nursing | Senior Theses

Many poor health outcomes later into adulthood have been triggered by adverse life events that have occurred during childhood. Most of the general population has experienced some sort of adverse childhood event that has negatively impacted their future health. Adverse childhood events include any traumatic event that has occurred during childhood including maltreatment (sexual abuse, mental abuse, and physical abuse), neglect, parental loss, and peer victimization.

Raising awareness regarding the opportunities to intervene in a child’s life as a means to prevent behavioral, psychological, and substance abuse disorders before they would typically manifest on their own is the ultimate goal. …

Cook's "The Asperkid’S Secret Book Of Social Rules:The Handbook Of (Not-So-Obvious) Neurotypical Social Guidelines For Autistic Teens (10th Anniversary Edition)" (Book Review), Amber C. Wessies

The Christian Librarian

No abstract provided.

Perceived Efficacy, Reduced Prescription Drug Use, And Minimal Side Effects Of Cannabis In Patients With Chronic Orthopedic Pain, Ari Greis, Eric Larsen, Conan Liu, Bryan Renslo, Anjithaa Radakrishnan, Adrianne R Wilson-Poe

Rothman Institute Papers

Introduction: Although cannabis is widely used for the treatment of chronic pain, most research relies on patient self-report and few studies have objectively quantified its efficacy and side effects. Extant inventories for measuring cannabis use were not designed to capture the medically relevant features of cannabis use, but rather were designed to detect problematic use or cannabis use disorder. Thus, we sought to capture the medically relevant features of cannabis use in a population of patients with orthopedic pain and pair these data with objective measures of pain and prescription drug use. Materials and Methods: In this prospective observational study, …

Voices That Matter: Boston Area Residents Of Color Discuss Climate Change, Lorena M. Estrada-Martínez, Paul Watanabe, Katsyris Rivera-Kientz

Sustainable Solutions Lab

This report presents findings from a qualitative study conducted by the Sustainable Solutions Lab at the University of Massachusetts Boston, centering on the climate change perspectives of 70 residents of color from the Greater Boston area. Through focus group discussions with Asian American, Black, Latino/a, and Native American participants, the study examines three core areas: the health impacts of climate change, levels of community preparedness, and individual and governmental responses. The findings reveal a shared concern over climate-related health vulnerabilities, structural barriers to climate preparedness, and a general mistrust of governmental leadership stemming from historical and ongoing racial inequities. Participants …

Technology-Enhanced In Vivo Exposures In Prolonged Exposure For Ptsd: A Pilot Randomized Controlled Trial, Tanya C Saraiya, Amber M Jarnecke, Alex O Rothbaum, Bethany Wangelin, Lisa M Mcteague, Ron Acierno, Delisa G Brown, Emily Bristol, Hayley Feigl, Mclain Reese, Adam R Cobb, Bill Harley, Robert J Adams, Sudie E Back

Faculty, Staff and Student Publications

In vivo exposures (IVEs) are a key component of exposure-based treatments, during which patients approach fear-provoking, yet safe, situations in "real life." This pilot study assessed the use of a wearable technology (Bio Ware) during IVEs to enhance Prolonged Exposure (PE) therapy for PTSD. Bio Ware provides a clinician dashboard with real-time physiological and subjective data for clinicians to use for virtually guided IVEs. Participants (N = 40) were randomized to a Guided group that received standard PE and virtual, clinician-guided IVEs with the Bio Ware device, or a Non-Guided group that received standard PE and used the Bio Ware …

Sport Management Study Abroad And International Exchange Program Innovation For A Post Covid-19 Era, James T. Morton, Chris Hanna, Jeffrey F. Levine

Kinesiology and Health Science Faculty Publications

The globalization of the sport industry has required sport management programs to create strategies for internationalizing students. Study abroad programs are a prominent example of those strategies. The COVID-19 pandemic had a significant impact on study abroad programs in Spring of 2020. Many students had their study abroad experiences either cut short or canceled all together. The purpose of this essay is to discuss how the student learning process can continue during an interruption or cancellation of study abroad and international exchange programs due to a pandemic or other global issues. Using an observational study, we asked the following research …

November / December 2022, Randy Curry, Cindy Brooks

RURAL ROCKS

This is the November & December 2022 issue of Rural Rocks from the SWOSU College of Pharmacy.

Swach 2022 Workforce Report: Understanding The Experiences Of The Healthconnect Hub Workforce, Natalie Royal Kenton, Benjamin Gronowski, Raven Susu-Mago, Abby Bush

Articles, Abstracts, and Reports

No abstract provided.

Intensivist -Driven Ventilator Management Shortens Duration Of Mechanical Ventilation In Coronary Artery Bypass Graft Surgery Patients, Yonatan Dollin, Brian Elliott, Ronald J. Markert, Angela Morman, Matthew Koroscil

Internal Medicine Faculty Publications

Background Prolonged mechanical ventilation in post Coronary Artery Bypass Graft Surgery (CABG) is associated with deleterious effects including, increased ICU and hospital length of stay (LOS), infectious complications, and mortality. Standardized ventilator weaning protocols and the utilization of critical care physicians in post CABG patient care vary substantially among institutions. The purpose of this study was to evaluate if intensivist consultation in conjunction with a multidisciplinary, standardized ventilator weaning protocol improves outcomes in CABG patients. Materials and Methods We performed a single-center, retrospective, before-after cohort analysis at Miami Valley Hospital in Dayton, OH, a 970-bed community hospital. Patients were divided …

Perceptions Of Orthopaedic Medicine Students And Their Supervisors About Practice-Based Learning: An Exploratory Qualitative Study, Muhamed Nsubuga, Robert Opoka, Moses Galukande, Ian G. Munabi, Aloysius . Mubuuke, Sarah Kiguli

Paediatrics and Child Health, East Africa

Background: Practice-based learning is crucial in forming appropriate strategies for improving learning among the medical students that support the country’s understaffed health sector. Unsatisfactory learning consequently results in poor performance of students and poor quality of health care workforce in the long run. Exploring the perceptions about the current practice-based learning system and how to improve is thus vital. This study set out to explore the perceptions of Orthopaedic medicine students and their supervisors about practice-based learning at a tertiary training hospital.

Methods: This was an exploratory phenomenological qualitative study that involved in-depth interviews among 10 Orthopedic students during their …

Single Low-Dose Targeted Bevacizumab Infusion In Adult Patients With Steroid-Refractory Radiation Necrosis Of The Brain: A Phase Ii Open-Label Prospective Clinical Trial, Shervin R. Dashti, Robert J. Kadner, Bradley S. Folley, Jason P. Sheehan, Dong Y. Han, Richard J. Kryscio, Mary B. Carter, Lisa B. E. Shields, Brian M. Plato, Renato V. La Rocca, Aaron C. Spalding, Tom L. Yao, Justin F. Fraser

Sanders-Brown Center on Aging Faculty Publications

OBJECTIVE There is an unmet need for safe and rapidly effective therapies for refractory brain radiation necrosis (RN). The aim of this prospective single-arm phase II trial was to evaluate the safety and efficacy of a single low-dose targeted bevacizumab infusion after blood-brain barrier disruption (BBBD) in adult patients with steroid-refractory brain RN.

METHODS Ten adults with steroid-refractory, imaging-confirmed brain RN were enrolled between November 2016 and January 2018 and followed for 12 months after treatment. Bevacizumab 2.5 mg/kg was administered as a one-time targeted intra-arterial infusion immediately after BBBD. Primary outcomes included safety and > 25% decrease in lesion volume. …

Exploring Risk Factors Of Alzheimer’S Disease Using Mouse Models, Xian Han

Theses and Dissertations (ETD)

Mouse models of Alzheimer’s disease (AD) that accurately recapitulate pathology and molecular changes are crucial for understanding disease mechanisms and subsequent therapeutic development. We examined five commonly used mouse models of AD (5xFAD, J20, APPNL-F, APPNL-G-F, Tau P301S) and compared their whole- and phosphoproteomes with human AD (the integration of three published datasets) to study whether they can mimic protein/RNA expression discrepancies, molecular changes, and enriched pathways found in human AD cases. The mouse models especially 5xFAD and APPNL-G-F show proteomic signatures similar to human AD but lack human-specific AD progressions, such as dysregulation of synaptic pathways and networks. Integration …

Impact Of The 2016 American College Of Surgeons Guideline Revision On Overlapping Lumbar Fusion Cases At A Large Academic Medical Center, Ali S. Farooqi, Austin J. Borja, Rashad Jabarkheel, Gregory Glauser, Krista Strouz, Scott Mcclintock, Neil R. Malhotra

Mathematics Faculty Publications

OBJECTIVE: The American College of Surgeons (ACS) u pdated its guidelines on overlapping surgery in 2016. The objective was to examine differences in postoperative outcomes after overlapping surgery either pre-ACS guide-line revision or post-guideline revision, in a coarsened exact matching sample. -METHODS: A total of 3327 consecutive adult patients u ndergoing single-level posterior lumbar fusion from 2013 to 2019 were retrospectively analyzed. Patients were separated into a pre-ACS guideline revision cohort (surgery before April 2016) or a post-guideline revision cohort (surgery after October 2016) for comparison. The primary outcomes were proportion of cases performed with any degree of overlap, and …

Perioperative Chanage In Cervical Lordosis And Health-Related Quality-Of-Life Outcomes, Jose A Canseco, Brian A Karamian, Parthik D Patel, Michael Markowitz, Joseph K Lee, Mark F Kurd, D Greg Anderson, Jeffrey A Rihn, Alan S Hilibrand, Christopher K Kepler, Alexander R Vaccaro, Gregory D Schroeder

Rothman Institute Papers

BACKGROUND: Surgeons have scrutinized spinal alignment and its impact on improving clinical outcomes following anterior cervical discectomy and fusion (ACDF). The primary analysis of this study examines the relationship between change in perioperative cervical lordosis (CL) and health-related quality-of-life (HRQOL) outcomes after ACDF. Secondary analysis evaluates the effects of fusion construct length on outcomes in patients grouped by preoperative cervical alignment.

METHODS: A retrospective cohort study was performed on an institutional database including patients who underwent 1- to 3-level ACDF. C2-C7 CL was measured preoperatively and at final follow-up. For primary analysis, patients were classified based on their perioperative cervical …

Effects Of Ethanol On Glun1/Glun2a And Glun1/Glun2b Nmda Receptor-Ion Channel Gating Kinetics, Robert W. Peoples, Hong Ren

Biomedical Sciences Faculty Research and Publications

Background

The N-methyl-D-aspartate receptor (NMDAR) is a major molecular target of alcohol action in the central nervous system, yet many aspects of alcohol's modulation of the activity of this ion channel remain unclear. We and others have shown that ethanol inhibition of NMDAR involves alterations in gating, especially a reduction in mean open time. However, a full description of ethanol's effects on NMDAR kinetics, including fitting them to a kinetic model, has not been reported.

Methods

To determine ethanol's effects on NMDAR kinetics, we used steady-state single-channel recording in outside-out patches from HEK-293 cells transfected with recombinant GluN1/GluN2A or …

Nursing Abroad: A Comparison Of Healthcare In Italy, Sweden, And The Us, Sadie Stark

The Eleanor Mann School of Nursing Undergraduate Honors Theses

No healthcare system is perfect, nor does one system work for all populations. History and culture have dictated the mindset of people for generations. It is the ever-changing mindset of patients and providers that will continue to expand and improve international healthcare by first changing daily practices. Nursing in Italy, Sweden, and the United States look very similar but also have a number of differences. Each country’s healthcare system works for its population, but efforts for international collaboration could still prove beneficial. Whether it be universal or private, centralized or localized, a patient centered focus is the driving force behind …

Rapid Detection Of Recurrent Non-Muscle Invasive Bladder Cancer In Urine Using Atr-Ftir Technology, Abdullah I. El-Falouji, Dalia M. Sabri, Naira M. Lofti, Doaa M. Medany, Samar A. Mohamed, Mai Alaa-Eldin, Amr Mounir Selim, Asmaa A. El Leithy, Haitham F. Kalil, Ahmed El-Tobgy, Ahmed Mohamed

Chemistry Faculty Publications

Non-muscle Invasive Bladder Cancer (NMIBC) accounts for 80% of all bladder cancers. Although it is mostly low-grade tumors, its high recurrence rate necessitates three-times-monthly follow-ups and cystoscopy examinations to detect and prevent its progression. A rapid liquid biopsy-based assay is needed to improve detection and reduce complications from invasive cystoscopy. Here, we present a rapid spectroscopic method to detect the recurrence of NMIBC in urine. Urine samples from previously-diagnosed NMIBC patients (n = 62) were collected during their follow-up visits before cystoscopy examination. Cystoscopy results were recorded (41 cancer-free and 21 recurrence) and attenuated total refraction Fourier transform infrared (ATR-FTIR) …

Good Faith: Surveillance And Evaluation Of 911 Good Samaritan Laws In The United States, Shane W. Reader

Dissertations and Theses (Open Access)

To fight soaring overdose mortality rates in the United States, lawmakers adopted a variety of harm reduction tools. Among these, 911 Good Samaritan Laws (GSLs) derive their name from the biblical parable of the Good Samaritan, a bystander who broke cultural convention to come to the aid of a man beset by thieves. These laws provide limited criminal immunity for bystanders in possession of controlled substances to encourage them to report drug overdoses. While previous studies associate GSLs with a modest reduction in opioid mortality, analyses often model them as equivocal or divide them coarsely across individual provisions. Evaluating these …

Equine Kinesiology Tape Application To Equine Hock Joints: Impact On Lameness And Movement Evaluation, Kiara Jones

Honors College Theses

Discomfort in the hocks of horses can cause lameness, resulting in poor performance. Diagnosis by veterinarians typically includes evaluating movement or use of ultrasound or radiography to evaluate tendons, ligaments, or bones. Treatment methods and times vary depending on diagnosis, but often include joint injections, medications, and stall rest. Treatments can be costly both financially and regarding time off from practice or competition. Alternative practices such as using equine kinesiology tape to support joints may improve comfort and movement for lower cost. The objective of this project was to evaluate the ease of use and effects of equine kinesiology tape …

Seroprevalence And Titer Concentration Testing For Leptospirosis In Equine, Ashley Himmelsbaugh

Honors College Theses

The most common best management practice used to combat diseases in horses is vaccination, which can decrease the incidence or severity of illness. However, the duration of immunity will vary for each vaccination and must be considered for revaccination purposes. Titer concentration, which evaluates antibodies in the blood, may be a helpful way of determining how long an animal has immunity to a disease. Leptospirosis, a zoonotic, bacterial disease, can result in uveitis, potentially leading to blindness, and abortion in mares. One serovar, Leptospirosis pomona (L. pomona), is associated with most cases of clinical disease in horses in North America. …

The Effects Of A Low Fodmap Diet On People With Irritable Bowel Syndrome: A Literature Review, Emily Stalder

The Eleanor Mann School of Nursing Undergraduate Honors Theses

Irritable Bowel Syndrome (IBS) is a very common gastrointestinal disorder around the world. There is no known etiology or cure for the disorder, which leaves researchers to develop coping mechanisms for this prevalent issue. A high percentage (10%-15%) of the general population, mostly in Western, industrialized areas, suffer from IBS. A low FODMAP diet (LFD) is something that has been gaining a following over the past 20 years, which has led to research on its ability to minimize symptoms of IBS. The purpose of this literature review is to see what current research has to offer on the LFD’s ability …

A Word From The Writing Team (December 2022), Pam Walter, Mfa, Liz Declan, Ma, Mfa

A Word From the Writing Team (Newsletter)

This issue includes:

• Writing Retreat—Happening This Week!
• BioRender Webinar—Next Week
• Coming in 2023

Tiny Tusks Internship: The Relationship Between Socioeconomic Status And Breastfeeding Barriers, Blair Finlinson

The Eleanor Mann School of Nursing Undergraduate Honors Theses

Tiny Tusks is a breastfeeding and infant support program developed by the nursing program at University of Arkansas. From 2021-2022, I have had the opportunity to complete my honors internship with this organization. Tiny Tusks was started with the goal of creating safe spaces for mothers to breastfeed and/or pump during school sporting events, along with providing up to date information on breastfeeding and infant safety practices. Tiny Tusks also provides changing tables, spaces for young children to decompress in a low-stimulation environment.

Exploring Stress In Adolescents Regarding The Covid-19 School Closure, Anna Beck

The Eleanor Mann School of Nursing Undergraduate Honors Theses

Background: The purpose of this literature review, is to explore the stress adolescents faced during the times of the COVID-19 pandemic. This includes the rates of stress, other psychological consequences, such as depression and anxiety, as well as factors that could have contributed to the development of stress and those that could have helped relieve feelings of distraught.

Purpose: To create a more holistic approach in nursing care, finding reasonings behind the creation of stress in the young population, as well as methods to alleviate, can help patient satisfaction and support.

Method: A literature review was conducted over 20 peer …

Exploring Parent Adverse Childhood Event Influence On Offspring Weight And Development, Angela Wurzer

The Eleanor Mann School of Nursing Undergraduate Honors Theses

Background: The purpose of this literature review is to explore the impact of parental adverse childhood events on weight and development in their offspring. This includes occurrences of offspring obesity, delays in social and cognitive development, and secondary factors that could have affected development or weight in childhood. Purpose: To support a more holistic and trauma-informed approach to nursing care, a systematic review was conducted examining the relationship between parent ACEs and offspring development and health status. Method: A literature review was conducted over 20 peer reviewed articles found on CINAHL Complete, PubMed and MEDLINE (Ebsco) databases. Results: A summary …

The Clinical Healthcare Provided To Homeless Communities Across The United States: A Literature Review, Saylor Sisemore

The Eleanor Mann School of Nursing Undergraduate Honors Theses

Homelessness has become a global public health concern as it results in poorer physical and mental health than age-matched people living in permanent housing (Ortiz & Roser, 2017). The area that comprises Northwest Arkansas (NWA), like other areas of the United States experiencing rapid growth, has seen a marked increase in the number of people experiencing homelessness in recent years. The homeless population is one of the most vulnerable and underserved groups of individuals in NWA and beyond. Public health nursing as a discipline is dedicated to providing compassionate care and exceptional service for all members of communities, with special …

Rare Causes Of Genital Fistula In Nine African Countries: A Retrospective Review, Carrie J. Ngongo, Thomas J.I.P. Raassen, Marietta Mahendeka, Ladeisha Lombard, Jos Van Roosmalen, Marleen Temmerman

Obstetrics and Gynaecology, East Africa

Background: Most genital fistulas result from prolonged, obstructed labor or surgical complications. Other causes include trauma (from accidents, traditional healers, or sexual violence), radiation, carcinoma, infection, unsafe abortion, and congenital malformation.

Methods: This retrospective records review focuses on rare fistula causes among 6,787 women who developed fistula after 1980 and sought treatment between 1994 and 2017 in Tanzania, Uganda, Kenya, Malawi, Zambia, Rwanda, Ethiopia, Somalia, and South Sudan. We compare fistula etiologies across countries and assess associations between rare causes and type of incontinence (urine, feces, or both).

Results: Rare fistula accounted for 1.12% (76/6,787) of all fistulas, including traumatic …

The East Africa Consortium For Human Papillomavirus And Cervical Cancer In Women Living With Hiv/Aids, Y. Tong, Elkanah Omenge, M. Nakalembe, P. Tonui, P. Itsura, K. Muthoka, M. Titus, S. Kiptoo, A. Mwangi, J. Ong’Echae

Obstetrics and Gynaecology, East Africa

The East Africa Consortium was formed to study the epidemiology of human papillomavirus (HPV) infections and cervical cancer and the influence of human immunodeficiency virus (HIV) infection on HPV and cervical cancer, and to encourage collaborations between researchers in North America and East African countries. To date, studies have led to a better understanding of the influence of HIV infection on the detection and persistence of oncogenic HPV, the effects of dietary aflatoxin on the persistence of HPV, the benefits of antiretroviral therapy on HPV persistence, and the differences in HPV detections among HIV-infected and HIV-uninfected women undergoing treatment for …

Trauma-Informed Care In Nursing Curricula: Development Of A Simulation-Based Educational Framework To Guide Health Professions, Heather Guest

Nursing Theses and Dissertations

Individuals of all ages, genders, social and ethnic backgrounds, and cultures suffer traumatic experiences. Trauma does not discriminate. The immense number of individuals struggling with trauma requires that health care providers approach patient care through a trauma-informed lens. Trauma-informed care is an evidence-based approach to patient-centered care and is vital to the healthcare provider-patient relationship. The increased responsibility of healthcare providers to provide trauma-informed care to all individuals demands a scientifically-based framework to guide the development of a trauma-informed health care professions education program. Healthcare simulation allows health professions’ students to experience real-life scenarios in a safe setting before transitioning …

A Machine Learning Approach For Predicting Patient Mortality With Heart Rate Variability Statistics, Matthew Thiele, Dario Ghersi

Theses/Capstones/Creative Projects

The prediction of patient mortality in the healthcare system provides a metric by which hospitals can better manage patient care and assess the needs of each individual patient. As such, the development of better predictive methods is vital for improving patient outcomes and overall quality of care. Heart rate variability (HRV) is a measure of the heart’s complex beating patterns, giving medical professionals additional insight into patient health. Previous research has demonstrated the potential use of heart rate variability as a metric for patient mortality prediction for various conditions, however more work is necessary to validate HRV as a metric …