Medicine and Health Sciences Commons^™

Rtx 300: Foundations Of Recreational Therapy Oer Curation, Chealsye Bowley

Curated OER Collections

This OER curation is an annotated bibliography of prospective OER for the GVSU course RTX 300: Foundations of Recreational Therapy, assembled by request from the instructor.

Nur 265: Introduction To Nursing Research And Evidence-Based Practice Oer Curation, Chealsye Bowley

Curated OER Collections

This OER curation is an annotated bibliography of prospective OER for the GVSU course NUR 265: Introduction to Nursing Research and Evidence-based Practice.

Mov 300: Kinesiology Oer Curation, Chealsye Bowley

Curated OER Collections

This OER curation is an annotated bibliography of prospective OER for the GVSU course MOV 300: Kinesiology, assembled by request from the instructor.

Pt 654: Applied Geriatric Practice Oer Curation, Chealsye Bowley

Curated OER Collections

This OER curation is an annotated bibliography of prospective OER for the GVSU course PT 654: Applied Geriatric Practice, assembled by request from the instructor.

Development Of A Point-Of-Care Ultrasonography Workflow Within A Rural Clinic, Lauren Myers

Masters Projects

Abstract

Background and Objectives: Healthcare has revolutionized with advancements in ultrasound technology. Among these advancements and the increasing availability of imaging modalities is point-of-care ultrasonography (POCUS) technology.

Problem: While POCUS has gained considerable ground in primary care, infrastructure to support its utility is deficient. The purpose of this project was to design, pilot, and evaluate a POCUS workflow to facilitate technology utilization and increase access to care.

Methods: Program development and evaluation involves the design, implementation, and evaluation of an evidence-based workflow for POCUS technology. The project was intended to address the needs of individuals in a rural setting. Participants …

Improving Patient Portal Enrollment Through Education And Technology At Rural Family Practice, Kelsey Crampton

Doctoral Dissertations & Projects

Background: Patient portals are available through many healthcare offices. They offer the opportunity to improve patient engagement and quality of patient care, but few patients enroll. At a small rural primary care office, less than 20% of the patients were enrolled in the patient portal.

Objective: The purpose of this quality improvement project was to address the barriers reported by patients at this clinic and determine whether changes in portal enrollment volume occurred. Reported barriers included a lack of knowledge about the portal and difficulties with the sign-up process.

Methods: Over three months, strategies included the development of a …

Reduction Of Mutant Atxn1 Rescues Premature Death In A Conditional Sca1 Mouse Model, James P Orengo, Larissa Nitschke, Meike E Van Der Heijden, Nicholas A Ciaburri, Harry T Orr, Huda Y Zoghbi

Duncan NRI Faculty and Staff Publications

Spinocerebellar ataxia type 1 (SCA1) is an adult-onset neurodegenerative disorder. As disease progresses, motor neurons are affected, and their dysfunction contributes toward the inability to maintain proper respiratory function, a major driving force for premature death in SCA1. To investigate the isolated role of motor neurons in SCA1, we created a conditional SCA1 (cSCA1) mouse model. This model suppresses expression of the pathogenic SCA1 allele with a floxed stop cassette. cSCA1 mice crossed to a ubiquitous Cre line recapitulate all the major features of the original SCA1 mouse model; however, they took twice as long to develop. We found that …

Alternating Pressure Overlay Systems, Maris Rathgeb

MSN Capstone Projects

Although preventable, pressure injuries are an overwhelming problem in the healthcare system and can lead to poor quality of life, increased length of hospitalization, and unsatisfactory patient outcomes. Many cardiac surgeries take anywhere from six to twelve hours, and patients are completely immobilized for the entire length of time. Alternating pressure overlays placed on the operating room table provide tissue offloading with inflating and deflating nodes, leading to micro-movements on high pressure bony prominences. The intervention PICO question to be answered in this paper is: In intraoperative patients (P), how does the use of an alternating pressure surface (I) compared …

Debunking Medical Myths: Can Blue Light Glasses Save Your Eyesight?, Sara Lehua Ma, Jad Baki, Lara Zraik, Tulsi Sadasivan, Wouter Ritsema, Nicolas Baroni

Patient Education Projects

No abstract provided.

Debunking Medical Myths: Not As Healthy As You Think, Jodene Takahashi, Huda Warsame, Caleb Richard, Janice Gibbons, Hadi El Ammar, Ahmad Kofahi

Patient Education Projects

No abstract provided.

Debunking Medical Myths: Vitamins And Supplements Always Make You Healthier, Bijan Sagman, Gokturk Tepe, Siena Snyder, Elena Carrillo, Itzick Nahmoud, William Crouch

Patient Education Projects

No abstract provided.

Debunking Medical Myths: Lung Damage Is Permanent. The Irreversible Damage Of Smoking, Daniel Kim, Parker Marsh, Jacob Katzman, Liana De La Torre, Mariam Samir, Pragathi Pathanjeli

Patient Education Projects

No abstract provided.

Debunking Medical Myths: Cracking Knuckles Leads To Arthritis., Erika Lopez, Jack Considine, Madeline Simone, Andranig Adjemian, Younes Motii, Jordan Akins

Patient Education Projects

No abstract provided.

Debunking Medical Myths: Vitamin C, Alem Cizmic, Elise Turke, Justin Lee, Rabe Al-Silwadi, Hope Baldwin, Katya Parker

Patient Education Projects

No abstract provided.

Concurrent P53 Mutation In Egfr Mutant Non-Small Cell Lung Cancer Is Associated With Resistance To First And Second Generation Egfr Tyrosine Kinase Inhibitors, A Meta-Analysis, Marissa Viola, Adam Kolatorowicz, Jun Wang

Research Day

Epidermal growth factor receptor (EGFR) mutant lung cancers tend to respond well to EGFR tyrosine kinase inhibitors (TKIs). However, resistance has been described. Molecular studies have revealed that concurrent mutations of tumor driver genes are associated with TKI resistance. To delineate the role of concurrent mutation of tumor suppressor gene p53 in TKI resistance, a meta-analysis was performed using published observations of EGFR mutant lung cancer patients treated with first or second generation TKIs. 31 studies are included in the analysis following a search of PubMed. Probability of TKI resistance and progress free survival (PFS) were compared in patients with …

Effects Of Parent Intervention Via Tele-Practice On Children With Autism Spectrum Disorder In Rural Mississippi, Erin Bowens

Honors Theses

Background

The present study explored the use of parent intervention via tele-practice for children with Autism Spectrum Disorders (ASD) and how effective that intervention was in increasing the child’s language and communication skills and the parents’ strategy use in the rural state of Mississippi.

Methods

Two dyads of participants were used. Dyad 1 included a mother and her 4-year-old son with high-functioning ASD, and Dyad 2 included a mother and her 4-year-old daughter with severe ASD. Standardized tests were administered to gather data about the children’s diagnoses. The study included four phases across four months, including pre-test, intervention, post-test, and …

Development Of A Non-Invasive Dna Extraction Method From Teeth, Monalisa Heng

Honors Theses

Forensic dentistry has evolved from simple morphological investigations to genetic and molecular analysis. One of the most important techniques is DNA analysis which requires viable samples from an individual or crime site. The orofacial region can be a good source for DNA samples because the tissues can resist environmental, thermal, electrical, and mechanical challenges. Teeth are especially useful as a source of genetic material because the DNA located in the pulp is surrounded by protective mineral tissue. The DNA in the pulp tissue is currently accessed through destructive methods involving crushing, pulverization, and splitting the tooth. Unfortunately, destructive methods destroy …

Use Of Wastewater Surveillance For Early Detection Of Alpha And Epsilon Sars-Cov-2 Variants Of Concern And Estimation Of Overall Covid-19 Infection Burden, Van Vo, Richard L. Tillett, Katerina Papp, Shirley Shen, Richard Gu, Andrew Gorzalski, Danielle Siao, Rayma Markland, Ching-Lan Chang, Hayley Baker, Jingchun Chen, Martin Schiller, Walter Q. Betancourt, Erin Buttery, Mark Pandori, Michael A. Picker, Daniel Gerrity, Edwin C. Oh

Nevada Institute of Personalized Medicine Faculty Research

A decline in diagnostic testing for SARS-CoV-2 is expected to delay the tracking of COVID-19 variants of concern and interest in the United States. We hypothesize that wastewater surveillance programs provide an effective alternative for detecting emerging variants and assessing COVID-19 incidence, particularly when clinical surveillance is limited. Here, we analyzed SARS-CoV-2 RNA in wastewater from eight locations across Southern Nevada between March 2020 and April 2021. Trends in SARS-CoV-2 RNA concentrations (ranging from 4.3 log10 gc/L to 8.7 log10 gc/L) matched trends in confirmed COVID-19 incidence, but wastewater surveillance also highlighted several limitations with the clinical data. Amplicon-based whole …

Assessing Psychological Impact Of Covid-19 Among Parents Of Children Returning To K-12 Schools: A U.S. Based Cross-Sectional Survey, Kavita Batra, Jennifer R. Pharr, Emylia Terry, Brian Labus

School of Medicine Faculty Research

Background and Purpose: While impacts of the pandemic on family well-being have been documented in the literature, little is known about the psychological challenges faced by children and their parents as schools reopen after mandated closures. Therefore, the purpose of this study was to determine if sending children back to in-person school impacts the mental health of parents and the perceived mental health of their children. Methods: This cross-sectional descriptive study recruited a nationally representative, non-probability sample of parents or guardians (n = 2100) of children attending grades K-12 in the United States (U.S.) through a 58-item web-based survey. The …

A Somatic Mutation In Moesin Drives Progression Into Acute Myeloid Leukemia, Ouyang Yuan, Jeffrey A Magee, Et Al.

Open Access Publications

Acute myeloid leukemia (AML) arises when leukemia-initiating cells, defined by a primary genetic lesion, acquire subsequent molecular changes whose cumulative effects bypass tumor suppression. The changes that underlie AML pathogenesis not only provide insights into the biology of transformation but also reveal novel therapeutic opportunities. However, backtracking these events in transformed human AML samples is challenging, if at all possible. Here, we approached this question using a murine in vivo model with an MLL-ENL fusion protein as a primary molecular event. Upon clonal transformation, we identified and extensively verified a recurrent codon-changing mutation (Arg

Hand Surgery Patient Perspectives On Medical Cannabis: A Survey Of Over 600 Patients, Lilah Fones, Clay Townsend, Harry Hoyen, Frederic Liss, Mark L. Wang, Ari C. Greis, Asif M. Ilyas

Rothman Institute Papers

Purpose: Medical cannabis (MC) has been proposed as a potential addition to multimodal pain man- agement regimens in orthopedics. This study evaluates hand and upper-extremity patient perspectives of MC as a treatment for common orthopedic and musculoskeletal pain conditions. This study also aims to identify the proportion of patients already using MC, perceived barriers to MC use, and opinions on insurance coverage and legality of cannabis.

Methods: An anonymous cross-sectional survey study was conducted of all patients at least 18 years old presenting from October 2020 to January 2021 to a hand and upper-extremity outpatient clinic. The survey collected information …

The Effect Of Estrogen On Gdnf Production Of Skeletal Muscle In Vitro, Hope Welter

Honors Theses

As life expectancy continues to rise, the number of people over age 65 in the U.S. is increasing. An aging population brings with it impacts on the national health system and associated economic expenditures. As individuals age, the skeletomuscular system suffers reduced function due to disease or conditions such as sarcopenia. Sarcopenia is characterized by muscular atrophy resulting from reduced muscle innervation. Exercise has been linked to prevention of sarcopenia, a suspected result of increased production of glial cell line-derived neurotrophic factor (GDNF). GDNF promotes neuronal survival, regeneration, and the formation of neuromuscular junctions. Therefore, treatments like exercise that increase …

Literature Review On Outer Hair Cell Regeneration And Potential Hearing Restoration, Serena Karlov

Honors Theses

The cochlea is the portion of the inner ear responsible for hearing, containing both the organ of Corti and auditory hair cells. Sound wave vibrations mechanically bend the stereocilia on the three rows of outer hair cells and one row of inner hair cells. These hair cells transduce this mechanical energy into electrical impulses that are relayed from the auditory nerve to the brain, where sounds are processed. In this review I provide an overview of inner ear anatomy, ear physiology, and auditory transduction. I then move on to specifically focus on the importance of outer hair cells, their regeneration, …

Three-Heartbeat Multilead Ecg Recognition Method For Arrhythmia Classification, Liang-Hung Wang, Yan-Ting Yu, Wei Liu, Lu Xu, Chao-Xin Xie, Tao Yang, I-Chun Kuo, Xin-Kang Wang, Jie Gao, Patricia Angela R. Abu

Department of Information Systems & Computer Science Faculty Publications

Electrocardiogram (ECG) is the primary basis for the diagnosis of cardiovascular diseases. However, the amount of ECG data of patients makes manual interpretation time-consuming and onerous. Therefore, the intelligent ECG recognition technology is an important means to decrease the shortage of medical resources. This study proposes a novel classification method for arrhythmia that uses for the very first time a three-heartbeat multi-lead (THML) ECG data in which each fragment contains three complete heartbeat processes of multiple ECG leads. The THML ECG data pre-processing method is formulated which makes use of the MIT-BIH arrhythmia database as training samples. Four arrhythmia classification …

A Comparison Of Positive And Negative Reinforcement To Decrease Disruptive Behavior During Medical Demands, Rachel Commodario

Thesis Projects

Medical demand tolerance is imperative for improving and maintaining physical health, but a disproportionate number of intellectually disabled individuals do not readily cooperate with medical procedure demands. Research suggests that although function-based treatments can be effective, in some contexts nonfunctional interventions can also produce therapeutic results (Briggs et al., 2019; Carter, 2010; Dowdy et al., 2018; Gardner et al., 2009; Lalli et al., 1999; Piazza et al., 1997). The purpose of this study was to compare the treatment effects of using functional and nonfunctional reinforcement to decrease escape-maintained medical demand noncooperation with intellectually disabled children. A reversal design embedded within …

Annual Hepatitis C Screening Qi: A Scoping Review, Sadiat Omowunmi Adebiyi Bsn, Rn, Sakinah Shaw Bsn, Rn, Tracy Mcclinton Dnp, Ag-Acnp-Bc, Sharon Little Dnp, Fnp-Bc, Aprn

Doctor of Nursing Practice Projects

Purpose/Background Despite the surge in HCV prevalence among pregnant women and the threat of perinatal HCV transmission, infants exposed to HCV in the United States are inadequately screened (Chappell et al., 2018). It is estimated that between 4% and 8% of babies exposed to HCV during pregnancy become infected (Watts et al., 2017). Incorporating Hep C screening with other mandated prenatal screening will play an essential role in reducing the complications associated with Hep C transmission to the newborn.

Methods Article search was done in the first three weeks of the fall 2021 semester, and a total of 63 articles …

Mycotic Aortic Aneurysm: A Rare Etiology Of Septic Shock., Kaitlin M Bowers, Vishnu Mudrakola, Christopher M Lloyd

Heart and Vascular Articles

Mycotic aneurysm of the aorta is a rare disease with a high mortality rate due to its likelihood of aneurysmal rupture. This syndrome is predominantly seen in patients over age 65 with the most common presenting symptoms being fever and back pain. Our case illustrates a mycotic aneurysm of the aorta presenting in an elderly female with vague abdominal pain, flank pain, and generalized weakness. We review the investigative approach, diagnostic modalities, and treatment options in patient management. This case emphasizes the need for a high index of suspicion of mycotic aneurysms of the aorta in critically ill elderly patients …

Debunking Medical Myths: 3 Myths Surrounding Coconut Oil, Tabassum Chowdhury, Kia Sweeney, Andrew Rabah, Andrew Gregory, Nicholas Livingston, Laura Aravena

Patient Education Projects

No abstract provided.

Debunking Medical Myths: Building Wellness Without Breaking Down Joints, Devin Mendez, Abhijay Kumar, Hannah Adams, Justin Padron, Bridget Croniger, Abrielle Holleran

Patient Education Projects

No abstract provided.

Debunking Medical Myths: Msg Safety, Meyer Gershater, Gabriella Shab, Amanda Rodriguez, Ahmad Chouman, Anthony Mrocko

Patient Education Projects

No abstract provided.