Medicine and Health Sciences Commons^™

The Mda Public Education Campaign: An X-Ray View, James Pond, Matt Maguy

The Journal of the Michigan Dental Association

The MDA Public Education Campaign has achieved significant engagement, surpassing previous milestones in video views and Find-a-Dentist searches. The article delves into the campaign's success, emphasizing its educational focus and strategic use of digital platforms. It explores the campaign's structure, target audience, and the integration of the Find-a-Dentist tool. With a shift from traditional TV commercials to digital advertising, the campaign's adaptability and real-time metrics are highlighted. The piece concludes by providing insights into the campaign's funding, oversight, and the content of the 2022 initiatives.

Yes, The Mda Stands For Something, Michael G. Maihofer Dds

The Journal of the Michigan Dental Association

In the President's address, Dr. Maihofer responds to concerns about the MDA's relevance, outlining four key points that emphasize its commitment to ethical dentistry, continuous education, advocacy, and adapting to changing professional needs. He highlights the MDA's role in opposing dental therapy, advocating for tax repeals, and promoting diversity, equity, and inclusion. Dr. Maihofer encourages member participation, emphasizing the collective strength of the MDA community. The address expresses gratitude to various contributors, including predecessor Dr. Steve Meraw, President-elect Dr. Vince Benivegna, the Board of Trustees, MDA staff, volunteers, and his wife, Denise.

J Mich Dent Assoc June 2022

The Journal of the Michigan Dental Association

Monthly, The Journal of the Michigan Dental Association brings news, information, and feature articles to our state's oral health community and the MDA's 6,200+ members. No publication reaches more Michigan dentists!

In this June 2022 issue, the reader will find the following original content:

• A cover feature on the MDA Public Education Campaign
• A 10-Minute EBD, "Are Neoplasms a Risk for Peri-Implantitis?"
• A feature on "The President’s Address to the House of Delegates"
• News you need: an Editorial, a Headquarters Report, Facts about MDA Peer Review, and regular department articles, Dentistry and the Law, Staff Matters, Advocacy, and component news …

Diabetes Knowledge: What Do College Students Know, Abdoulaye Diallo, Roy K. Chen, Mohammed Mozadded Hossen, J. Luna, Diana Paz, Eva Arjona

School of Rehabilitation Services & Counseling Faculty Publications

This study investigates students’ knowledge about diabetes, with a focus on academic disciplines and gender. Data were collected from 218 students enrolled at a large public university. Descriptive statistics were employed, and factorial analysis of variance (ANOVA) were performed. The results showed that, while participants seemed to have some knowledge about diabetes, they generally lacked specific content information about the disease. Female students outperformed male students in diabetes knowledge. Rehabilitation counselor educators can offer an invaluable service by covering the topic of diabetes in their courses and curricula. They can consider incorporating specific information about diabetes that can better prepare …

Asthma Exacerbation, Children's Mercy Kansas City

Clinical Pathways (Formally Known As Clinical Practice Guidelines)

No abstract provided.

Assessment Of Abdominal Fat Distribution By Computed Tomography In Obese Dogs, Yunseo Jang, Hyemin Na, Sooyoung Choi, Hojung Choi, Youngwon Lee, Kija Lee

The Thai Journal of Veterinary Medicine

Obesity is a risk factor for canine health but there has been no study on the tendency of body fat accumulation naturally occurring in obese dogs. This retrospective observational study aims to evaluate the tendency to accumulate visceral and subcutaneous fat using computed tomography (CT) in naturally occurring obese dogs. The study included 15 dogs with a body condition score of 8 or 9 that underwent abdominal CT scans. Total fat area (TA), visceral fat area (VA), subcutaneous fat area (SA) and body area (BA) were measured by non-contrast transverse image at the third lumbar vertebra (L3) and the sixth …

Stifle Joint Reconstruction Technique Using Fascia Lata In A Cat With Cranial Cruciate Ligament Rupture, Hern-Yeu Lee, Wei-Yau Shia, Tien-Huan Hsu, Wei-Ming Lee

The Thai Journal of Veterinary Medicine

A two-year-old spayed female mongrel cat presenting with right hind limb lameness with intermittent weight bearing while walking was taken to the veterinary medicine teaching hospital of National Chung Hsing University. Both drawer test and tibial compression test were positive, stifle radiography showed synovial fluid had become more radiopaque. The tentative diagnosis for the cat was rupture of the right cranial cruciate ligament (CrCL), medical management using corticosteroids was prescribed with anticoagulants and surgical treatment recommended. Intracapsular reconstruction was performed and the postoperative recovery of this cat presented normal physical status with improved right hind limb weight-bearing activity. This report …

The Relationship Between Voting Restrictions And Covid-19 Case And Mortality Rates Between Us Counties, Roman Pabayo, Erin Grinshteyn, Brian Steele, Peter Muennig, Sze Yan Liu

Department of Public Health Scholarship and Creative Works

Background

Since the 2010 election, the number of laws in the U.S. that create barriers to voting has increased dramatically. These laws may have spillover effects on population health by creating a disconnect between voter preferences and political representation, thereby limiting protective public health policies and funding. We examine whether voting restrictions are associated with county-level COVID-19 case and mortality rates.

Methods

To obtain information on restricted access to voting, we used the Cost of Voting Index (COVI), a state-level measure of barriers to voting during a U.S. election from 1996 to 2016. COVID-19 case and mortality rates were obtained …

Perceived Barriers To Peritoneal Dialysis Among Kenyan Nephrologists: A Cross-Sectional Descriptive Study, Saleem Abdul Karim Sokwala, John Otieno Odhiambo, Ahmed Sokwala

Internal Medicine, East Africa

Background: Peritoneal dialysis (PD) is a well-recognized technique of renal replacement therapy (RRT), with similar efficacy as well as survival outcomes as hemodialysis (HD). Despite its advantages including prolonged preservation of residual renal function, potentially lower cost and advances with automated techniques, and commercialization of more biocompatible solutions, the overall prevalence of patients treated with PD is still very low in developed countries and even more so in Africa and low-middle income countries like Kenya. According to our knowledge, no local studies have been done on prevalence of peritoneal dialysis or on potential barriers to utilization of PD as an …

The Effects Of Dangerous World Beliefs On Covid-19 Preventive Behaviors In Singapore: The Moderating Role Of Public Health Communication, Su Lin Yeo, Desiree Y. Phua, Ying-Yi Hong

Research Collection Lee Kong Chian School Of Business

This research purposes to examine the role of strategic communication, specifically the effectiveness of government's crisis communication messages at the onset of COVID-19 pandemic in Singapore, on disease preventive behaviors. It employed a mixed method research approach by first carrying out a content analysis of 7128 news headlines on COVID-19 to confirm our presupposition that the media may be communicating messages that the world order is being threatened. Informed by our findings that 90% of news reports were framed to suggest a dangerous world, we surveyed 453 respondents in the main study, and tested if people's beliefs in a dangerous …

Does Gender Impact A Diagnosis Of Ankylosing Spondylitis?, Mark C Hwang, Martin Rozycki, David Kauffman, Theresa Arndt, Esther Yi, Michael H Weisman

Faculty, Staff and Student Publications

Objective: The study objective was to explore differences in ankylosing spondylitis (AS) diagnosis experiences between men and women by examining the coding of health events over the 2 years preceding AS diagnosis.

Methods: Claims data (January 2006-April 2019) from the MarketScan databases were examined. Patients who had received two or more AS diagnoses at least 30 days apart and had at least 2 years of insurance enrollment before their first AS diagnosis were analyzed. Men were matched 1:1 to women by age, diagnosis date, insurance type, and enrollment duration. Health events (diagnosis and provider codes) were examined over 2 years …

A Word From The Writing Team (June 2022), Pam Walter, Mfa, Liz Declan, Ma, Mfa

A Word From the Writing Team (Newsletter)

This issue includes:

• Exciting News about Biorender, A Simple Tool For Making Great Graphics
• Writing Opportunity
• Writing Retreats
• Quick Reminder

Exploratory Investigation Of The Plasma Proteome Associated With The Endotheliopathy Of Trauma, Joseph D Krocker, Kyung Hyun Lee, Hanne H Henriksen, Yao-Wei Willa Wang, Erwin M Schoof, Sigurdur T Karvelsson, Óttar Rolfsson, Pär I Johansson, Claudia Pedroza, Charles E Wade

Faculty, Staff and Student Publications

Background: The endotheliopathy of trauma (EoT) is associated with increased mortality following injury. Herein, we describe the plasma proteome related to EoT in order to provide insight into the role of the endothelium within the systemic response to trauma.

Methods: 99 subjects requiring the highest level of trauma activation were included in the study. Enzyme-linked immunosorbent assays of endothelial and catecholamine biomarkers were performed on admission plasma samples, as well as untargeted proteome quantification utilizing high-performance liquid chromatography and tandem mass spectrometry.

Results: Plasma endothelial and catecholamine biomarker abundance was elevated in EoT. Patients with EoT (n = 62) …

Nexmif Pathogenic Variants In Individuals Of Korean, Vietnamese, And Mexican Descent, Elizabeth Langley, Laura S Farach, Mary K Koenig, Hope Northrup, David F Rodriguez-Buritica, Kate Mowrey

Faculty, Staff and Student Publications

NEXMIF pathogenic variants have been known to produce a wide spectrum of X-linked intellectual disability (ID) in both males and females. Thus far, few individuals from diverse populations have been described with NEXMIF-related disorders. Herein, we report three individuals with NEXMIF pathogenic variants, the first two are the only males of Korean and Vietnamese descent described with this disorder to our knowledge. The last patient is a Hispanic female who harbors the same pathogenic variant as a previously described Caucasian individual, but with differing clinical presentation. These patients present with many classic symptoms of NEXMIF-related disorders including ID, epilepsy, developmental …

Walking Improvement In Chronic Incomplete Spinal Cord Injury With Exoskeleton Robotic Training (Wise): A Randomized Controlled Trial, Dylan J Edwards, Gail Forrest, Mar Cortes, Margaret M Weightman, Cristina Sadowsky, Shuo-Hsiu Chang, Kimberly Furman, Amy Bialek, Sara Prokup, John Carlow, Leslie Vanhiel, Laura Kemp, Darrell Musick, Marc Campo, Arun Jayaraman

Faculty, Staff and Student Publications

Study design: Clinical trial.

Objective: To demonstrate that a 12-week exoskeleton-based robotic gait training regimen can lead to a clinically meaningful improvement in independent gait speed, in community-dwelling participants with chronic incomplete spinal cord injury (iSCI).

Setting: Outpatient rehabilitation or research institute.

Methods: Multi-site (United States), randomized, controlled trial, comparing exoskeleton gait training (12 weeks, 36 sessions) with standard gait training or no gait training (2:2:1 randomization) in chronic iSCI (>1 year post injury, AIS-C, and D), with residual stepping ability. The primary outcome measure was change in robot-independent gait speed (10-meter walk test, 10MWT) post 12-week intervention. Secondary …

Using Artificial Neural Networks To Predict Intra-Abdominal Abscess Risk Post-Appendectomy, Morouge M Alramadhan, Hassan S Al Khatib, James R Murphy, Kuojen Tsao, Michael L Chang

Faculty, Staff and Student Publications

OBJECTIVE: To determine if artificial neural networks (ANN) could predict the risk of intra-abdominal abscess (IAA) development post-appendectomy.

BACKGROUND: IAA formation occurs in 13.6% to 14.6% of appendicitis cases with "complicated" appendicitis as the most common cause of IAA. There remains inconsistency in describing the severity of appendicitis with variation in treatment with respect to perforated appendicitis.

METHODS: Two "reproducible" ANN with different architectures were developed on demographic, clinical, and surgical information from a retrospective surgical dataset of 1574 patients less than 19 years old classified as either negative (n = 1,328) or positive (n = 246) for IAA post-appendectomy …

Part I Antimicrobial Resistance: Bacterial Pathogens Of Dermatologic Significance And Implications Of Rising Resistance, Saira George, Fiorinda F Muhaj, Celine D Nguyen, Stephen K Tyring

Faculty, Staff and Student Publications

Although the COVID-19 pandemic has been the defining global health crisis of our time, public health officials have been sounding the alarm of another ominous threat for years: an impending antimicrobial resistance crisis. In dermatology, antibiotics are often used for prolonged courses in the treatment of skin and soft tissue infections and common inflammatory skin conditions, increasing the risk of microbiome alteration and antibiotic-related adverse effects, all while exerting consequential selective pressures on both pathogenic and bystander bacteria. In this review, we hope to raise awareness of the crisis of antimicrobial resistance and review resistance concerns related to dermatology-relevant bacterial …

The Long Β2,3-Sheets Encoded By Redundant Sequences Play An Integral Role In The Channel Function Of P2x7 Receptors, Xue-Fei Ma, Ting-Ting Wang, Wen-Hui Wang, Li Guan, Chang-Run Guo, Xing-Hua Li, Yun-Tao Lei, Ying-Zhe Fan, Xiao-Na Yang, Motoyuki Hattori, Osamu Nureki, Michael X Zhu, Ye Yu, Yun Tian, Jin Wang

Faculty, Staff and Student Publications

P2X receptors are a class of nonselective cation channels widely distributed in the immune and nervous systems, and their dysfunction is a significant cause of tumors, inflammation, leukemia, and immune diseases. P2X7 is a unique member of the P2X receptor family with many properties that differ from other subtypes in terms of primary sequence, the architecture of N- and C-terminals, and channel function. Here, we suggest that the observed lengthened β2- and β3-sheets and their linker (loop β2,3), encoded by redundant sequences, play an indispensable role in the activation of the P2X7 receptor. We show that deletion of this longer …

47xxy And 47xxx In Scleroderma And Myositis, R Hal Scofield, Valerie M Lewis, Joshua Cavitt, Biji T Kurien, Shervin Assassi, Javier Martin, Olga Gorlova, Peter Gregersen, Annette Lee, Lisa G Rider, Terrance O'Hanlon, Simon Rothwell, James Lilleker, Myositis Genetics Consortium, Yuta Kochi, Chikacshi Terao, Ann Igoe, Wendy Stevens, Joanne Sahhar, Janet Roddy, Maureen Rischmueller, Sue Lester, Susanna Proudman, Sixia Chen, Matthew A Brown, Maureen D Mayes, Janine A Lamb, Frederick W Miller

Faculty, Staff and Student Publications

Objective: We undertook this study to examine the X chromosome complement in participants with systemic sclerosis (SSc) as well as idiopathic inflammatory myopathies.

Methods: The participants met classification criteria for the diseases. All participants underwent single-nucleotide polymorphism typing. We examined X and Y single-nucleotide polymorphism heterogeneity to determine the number of X chromosomes. For statistical comparisons, we used χ2 analyses with calculation of 95% confidence intervals.

Results: Three of seventy men with SSc had 47,XXY (P = 0.0001 compared with control men). Among the 435 women with SSc, none had 47,XXX. Among 709 men with polymyositis or dermatomyositis (PM/DM), seven …

Pneumothorax And Pneumomediastinum In Covid-19: A Case Series, Stephan Reyes, Brad Roche, Farah Kazzaz, Daniel Ocazionez, Aditya P Lal, Rosa M Estrada-Y-Martin, Sujith V Cherian

Faculty, Staff and Student Publications

COVID- 19 has become a major pandemic affecting more than 11 million people worldwide. Common radiological manifestations of COVID-19 include peripheral based ground-glass or consolidative opacities; however, pneumothorax and pneumo-mediastinum are very rare manifestations; even more so within patients not on mechanical ventilation. We present a case series of 5 patients with COVID-19 who either presented with or developed spontaneous pneumothorax or pneumo-mediastinum within the course of hospitalization. With the exception of one patient, all other patients developed pneumothorax as a late manifestation in their illness; more than 10 days after initial symptom onset in COVID-19. From within this case …

Patient Perception Of Voxelotor Treatment Benefit In Sickle Cell Disease, Modupe Idowu, Anam Haque, Elisa M Williams, Arthi Sridhar

Faculty, Staff and Student Publications

Patients with sickle cell disease (SCD) experience a range of clinical symptoms, including acute and chronic pain, fatigue, and respiratory problems, as well as chronic organ complications that can lead to disability and accelerated mortality. Voxelotor is a first-in-class therapy that targets sickle hemoglobin polymerization, the root cause of SCD. It is approved by the US Food and Drug Administration for treatment of SCD in patients aged 4 years and older and in the European Union and United Arab Emirates for the treatment of SCD in patients aged 12 years and older. Here, we report the single-center experience of both …

Anal Cytology Screening In Men Who Have Sex With Men With Hiv At A University Hospital In Bogotá, Colombia, I Tatiana Ordoñez-Blanco, Samuel Martínez-Vernaza, Kevin J Blair, Camilo Quiroga, Ellen Lowenstein, Luis J Lombana Amaya, Jesse Clark, Jordan E Lake, Sandra Liliana Valderrama-Beltrán

Faculty, Staff and Student Publications

Background: Risk of anal squamous cell carcinoma (anal cancer) is greater among men who have sex with men (MSM) living with human immunodeficiency virus (HIV). We describe the frequency of and factors associated with abnormal anal cytology results in Colombian MSM living with HIV.

Methods: This retrospective observational cohort study included MSM ≥18 years old living with HIV screened with anal cytology at Hospital Universitario San Ignacio in Bogotá, Colombia between January 2019 and February 2020. A multivariable log-binomial regression model estimated associations with abnormal anal cytology.

Results: A total of 211 patients were included. Mean age was 35.6 years. …

Klif-Associated Cytoskeletal Proteins In Trypanosoma Brucei Regulate Cytokinesis By Promoting Cleavage Furrow Positioning And Ingression, Qing Zhou, Huiqing Hu, Ziyin Li

Faculty, Staff and Student Publications

Cytokinesis in the early divergent protozoan Trypanosoma brucei occurs from the anterior cell tip of the new-flagellum daughter toward the nascent posterior end of the old-flagellum daughter of a dividing biflagellated cell. The cleavage furrow ingresses unidirectionally along the preformed cell division fold and is regulated by an orphan kinesin named kinesin localized to the ingressing furrow (KLIF) that localizes to the leading edge of the ingressing furrow. Little is known about how furrow ingression is controlled by KLIF and whether KLIF interacts with and cooperates with other cytokinesis regulatory proteins to promote furrow ingression. Here, we investigated the roles …

A Wireless Millimetric Magnetoelectric Implant For The Endovascular Stimulation Of Peripheral Nerves, Joshua C Chen, Peter Kan, Zhanghao Yu, Fatima Alrashdan, Roberto Garcia, Amanda Singer, C S Edwin Lai, Ben Avants, Scott Crosby, Zhongxi Li, Boshuo Wang, Michelle M Felicella, Ariadna Robledo, Angel V Peterchev, Stefan M Goetz, Jeffrey D Hartgerink, Sunil A Sheth, Kaiyuan Yang, Jacob T Robinson

Faculty, Staff and Student Publications

Implantable bioelectronic devices for the simulation of peripheral nerves could be used to treat disorders that are resistant to traditional pharmacological therapies. However, for many nerve targets, this requires invasive surgeries and the implantation of bulky devices (about a few centimetres in at least one dimension). Here we report the design and in vivo proof-of-concept testing of an endovascular wireless and battery-free millimetric implant for the stimulation of specific peripheral nerves that are difficult to reach via traditional surgeries. The device can be delivered through a percutaneous catheter and leverages magnetoelectric materials to receive data and power through tissue via …

Outcomes And Return-To-Sport Rates For Elite Athletes With Femoral Retroversion Undergoing Hip Arthroscopy: A Propensity-Matched Analysis With Minimum 2-Year Follow-Up, Jade S Owens, Andrew E Jimenez, Michael S Lee, David R Maldonado, Ajay C Lall, Benjamin G Domb

Faculty, Staff and Student Publications

BACKGROUND: Return to sports (RTS) and patient-reported outcomes (PROs) for elite athletes with femoral version abnormalities undergoing hip arthroscopy have not been well established.

PURPOSES: To (1) report minimum 2-year PROs and RTS rates in elite athletes with femoral retroversion who underwent primary hip arthroscopy and (2) compare clinical results to those of a propensity-matched control group of elite athletes with normal femoral version who underwent primary hip arthroscopy.

STUDY DESIGN: Cohort study; Level of evidence, 3.

METHODS: Data were prospectively collected and retrospectively reviewed for elite (professional and collegiate) athletes with femoral version1, hip dysplasia, and previous ipsilateral hip …

Is Nonoperative Treatment Appropriate For All Patients With Type 1 Tibial Spine Fractures? A Multicenter Study Of The Tibial Spine Research Interest Group, Jilan L Shimberg, Tomasina M Leska, Aristides I Cruz, Henry B Ellis, Neeraj M Patel, Yi-Meng Yen, Tibial Spine Research Interest Group, Gregory A Schmale, R Justin Mistovich, Peter D Fabricant, Theodore J Ganley, Daniel W Green, Benjamin Johnson, Indranil Kushare, R Jay Lee, Scott D Mckay, Todd A Milbrandt, Jason Rhodes, Brant Sachleben, Jessica L Traver

Faculty, Staff and Student Publications

BACKGROUND: Type 1 tibial spine fractures are nondisplaced or ≤2 mm-displaced fractures of the tibial eminence and anterior cruciate ligament (ACL) insertion that are traditionally managed nonoperatively with immobilization.

HYPOTHESIS: Type 1 fractures do not carry a significant risk of associated injuries and therefore do not require advanced imaging or additional interventions aside from immobilization.

STUDY DESIGN: Case series; Level of evidence, 4.

METHODS: We reviewed 52 patients who were classified by their treating institution with type 1 tibial spine fractures. Patients aged ≤18 years with pretreatment plain radiographs and ≤ 1 year of follow-up were included. Pretreatment imaging was …

Care Levels For Fetal Therapy Centers, Ahmet A Baschat, Sean B Blackwell, Debnath Chatterjee, James J Cummings, Stephen P Emery, Shinjiro Hirose, Lisa M Hollier, Anthony Johnson, Sarah J Kilpatrick, Francois I Luks, M Kathryn Menard, Lawrence B Mccullough, Julie S Moldenhauer, Anita J Moon-Grady, George B Mychaliska, Michael Narvey, Mary E Norton, Mark D Rollins, Eric D Skarsgard, Kuojen Tsao, Barbara B Warner, Abigail Wilpers, Greg Ryan

Faculty, Staff and Student Publications

Fetal therapies undertaken to improve fetal outcome or to optimize transition to neonate life often entail some level of maternal, fetal, or neonatal risk. A fetal therapy center needs access to resources to carry out such therapies and to manage maternal, fetal, and neonatal complications that might arise, either related to the therapy per se or as part of the underlying fetal or maternal condition. Accordingly, a fetal therapy center requires a dedicated operational infrastructure and necessary resources to allow for appropriate oversight and monitoring of clinical performance and to facilitate multidisciplinary collaboration between the relevant specialties. Three care levels …

Aims: Increasing Diversity In Graduate Medical Education Leadership, Lahia Yemane, Emma Omoruyi, Patricia Poitevien, Rebecca Blankenburg

Faculty, Staff and Student Publications

No abstract provided.

Effects Of A Workplace Exercise Intervention On Cardiometabolic Health: Randomized Controlled Trial, Ali Muneer Al Rahma

Dissertations

Brief Introduction: The worldwide rising levels of physical inactivity, especially in the United Arab Emirates (UAE) and the Eastern Mediterranean region, are alarming. The UAE reports one of the highest rates of mortality due to non-communicable diseases, and insufficient physical activity is a major underlying cause. Therefore, action is required to reduce physical inactivity using evidence-based strategies.
/="/">Aims: To evaluate the effect of a 12-week workplace structured exercise intervention on cardiometabolic risk factors and to determine whether the workplace exercise intervention improves physical activity levels four weeks post-intervention.
/="/">Methods: This is a pragmatic parallel, randomized controlled trial with …

The Pendulum Of Fontan Fenestration, Nadia Hernandez, Sudipta Sen, Johanna Blair De Haan, Stephen Haskins, Amit Pawa

Faculty, Staff and Student Publications

No abstract provided.