Medicine and Health Sciences Commons^™

Can Integrated Interventions Create The Conditions That Support Caregiving For Better Child Growth?, Purnima Menon, Edward A. Frongillo Jr.

Faculty Publications

No abstract provided.

Alcohol Abuse And Mental Health Disorders In United States Veterans, Heidi Prentice

Nursing Capstones

No abstract provided.

An Undergraduate Curriculum In Public Health Benchmarked To The Needs Of The Workforce, J. Michael Stoots, Randy Wykoff, Amal Khoury, Robert P. Pack

ETSU Faculty Works

East Tennessee State University (ETSU) has offered an undergraduate degree in public health for 60 years. Alumni survey data have documented that the majority of the graduates from this program enter the workforce [see accompanying commentary by Wykoff, et al. (1)]. To keep pace with ongoing changes in the workforce, the decision was made to completely review, and, as appropriate, revise and restructure the Bachelor of Science in Public Health (BSPH) curriculum.

Regulation Of Kv2.1 Channel Inactivation By Phosphatidylinositol 4,5-Bisphosphate., Mayra Delgado-Ramírez, José J De Jesús-Pérez, Iván A Aréchiga-Figueroa, Jorge Arreola, Scott K Adney, Carlos A. Villalba-Galea, Diomedes E Logothetis, Aldo A Rodríguez-Menchaca

School of Pharmacy Faculty Articles

Phosphatidylinositol 4,5-bisphosphate (PIP2) is a membrane phospholipid that regulates the function of multiple ion channels, including some members of the voltage-gated potassium (Kv) channel superfamily. The PIP2 sensitivity of Kv channels is well established for all five members of the Kv7 family and for Kv1.2 channels; however, regulation of other Kv channels by PIP2 remains unclear. Here, we investigate the effects of PIP2 on Kv2.1 channels by applying exogenous PIP2 to the cytoplasmic face of excised membrane patches, activating muscarinic receptors (M1R), or depleting endogenous PIP2 using a rapamycin-translocated 5-phosphatase (FKBP-Inp54p). Exogenous PIP2 rescued Kv2.1 channels from rundown and partially …

Week Of January 29, 2018, New York Medical College

InTouch

• Flu Vaccine Expert Doris J. Bucher, Ph.D., to Address 22nd Annual Medical Student Research Forum
• Andrew Mutnick, M.D. '01, Is Named SOM Interim Senior Associate Dean for Student Affairs

Factor Xii And Upar Upregulate Neutrophil Functions To Influence Wound Healing, Evi X. Stavrou, Chao Fang, Kara L. Bane, Erdem Kucukal, Agharnan Gandhi, Adina Brett-Morris, Michele M. Mumaw, Alona Merkulova, Cindy C. Reynolds, Omar Alhalabi, Lalitha V. Nayak, Wen-Mei Yu, Cheng-Kui Qu, Howard J. Meyerson, George R. Dubyak, Umut A. Gurkan, Marvin T. Nieman, Anirban Sen Gupta, Alvin H. Schmaier

Faculty Scholarship

Coagulation factor XII (FXII) deficiency is associated with decreased neutrophil migration, but the mechanisms remain uncharacterized. Here, we examine how FXII contributes to the inflammatory response. In 2 models of sterile inflammation, FXII-deficient mice (F12–/–) had fewer neutrophils recruited than WT mice. We discovered that neutrophils produced a pool of FXII that is functionally distinct from hepatic-derived FXII and contributes to neutrophil trafficking at sites of inflammation. FXII signals in neutrophils through urokinase plasminogen activator receptor–mediated (uPAR-mediated) Akt2 phosphorylation at S474 (pAktS474). Downstream of pAkt2S474, FXII stimulation of neutrophils upregulated surface expression of αMβ2 integrin, increased intracellular calcium, and promoted …

Medical School Watercooler Newsletter - January 28, 2018, Lindsey Lyle

Watercooler Newsletter

This is the January 28, 2018 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

• Clark Appointed Clinical Project Leader for TCPi
• USA Researchers Targeting Preventable Blindness With Local Lions Clubs' Support
• Running for Hope - Help Dr. Phillip Fields Gain Entry into Boston Marathon

Developmental Constraint Through Negative Pleiotropy In The Zygomatic Arch., Christopher J Percival, Rebecca Green, Charles C Roseman, Daniel M. Gatti, Judy Morgan, Stephen A Murray, Leah Rae Donahue, Jessica M Mayeux, K Michael Pollard, Kunjie Hua, Daniel Pomp, Ralph Marcucio, Benedikt Hallgrímsson

Faculty Research 2018

Background: Previous analysis suggested that the relative contribution of individual bones to regional skull lengths differ between inbred mouse strains. If the negative correlation of adjacent bone lengths is associated with genetic variation in a heterogeneous population, it would be an example of negative pleiotropy, which occurs when a genetic factor leads to opposite effects in two phenotypes. Confirming negative pleiotropy and determining its basis may reveal important information about the maintenance of overall skull integration and developmental constraint on skull morphology.

Results: We identified negative correlations between the lengths of the frontal and parietal bones in the midline cranial …

Exploring Health Care Seeking Knowledge, Perceptions And Practices For Childhood Diarrhea And Pneumonia And Their Context In A Rural Pakistani Community, Wafa Aftab, Leah Shipton, Fauziah Rabbani, Kashif Sangrasi, Shagufta Perveen, Aysha Zahidie, Imran Naeem, Shamim Qazi

Community Health Sciences

BACKGROUND:

Where access to facilities for childhood diarrhea and pneumonia is inadequate, community case management (CCM) is an effective way of improving access to care. In Pakistan, utilization of CCM for these diseases through the Lady Health Worker Program remains low. Challenges of access to facilities persist leading to delayed care and poor outcomes. Estimating caregiver knowledge, understanding their perceptions and practices, and recognizing how these are related to care seeking decisions about childhood diarrhea and pneumonia is crucial to bring about coherence between supply and demand-side practices.

METHODS:

Data was collected from family caregivers to explore their knowledge, perceptions …

Understanding Diabetes-Related Distress Characteristics And Psychosocial Support Preferences Of Urban African American Adults Living With Type 2 Diabetes: A Mixed-Methods Study, Sula Marie Hood, Amy Irby-Shasanmi, Mary De Groot, Elissabeth Martin, Andrew S. Lajoie

Faculty and Staff Scholarship

Purpose

Methods

Multiple Complications From A Finger Fracture In A Basketball Player, Stephen Hajdas

The Pegasus Review: UCF Undergraduate Research Journal

Minor finger and hand problems resulting from NCAA Division-1 Basketball competition are fairly common. True injuries— those requiring removal from participation— are rare, as suggested by injury surveillance and epidemiological data. The objective of this study is to present the case of multiple complications resulting from an original finger dislocation and fracture. Improper fracture healing led to tendon imbalances, causing finger angulation. The extended period of time the finger was deformed further resulted in osteoarthritis (progressive wearing down of the cartilage and bones that comprise a joint). Severe complications stemming from the original injury occur infrequently in the general population …

Factors Associated With Eating Disorders In Women, Christina Knowles

The Pegasus Review: UCF Undergraduate Research Journal

Although various factors associated with eating disorders have been studied, no comprehensive source of research findings was identified in this review. The purpose of this study was to identify and synthesize research findings of factors associated with eating disorders in women published from 1992-2008. These findings may be useful to nurses, other professionals, families, and the public to facilitate the prevention, recognition, treatment, and rehabilitation of women with eating disorders.

The factors most closely associated with eating disorders identified through this review were depression, sexual abuse, substance abuse, anxiety disorders, early pubertal onset and the personality traits of perfectionism and …

Improving Male Middle School Nursing Recruitment: A Comprehensive Approach For Students, Families, And Counselors, Robert M. Patterson

DNP Qualifying Manuscripts

Middle school students have been identified as the prime age group to begin nursing recruitment efforts (Matutina, Newman & Jenkins, 2010); however, the current practice of recruiting middle school, male students is ineffective in increasing the number of new nurses. Efforts are required to encourage young, male students to consider nursing as a potential career choice, but this can’t be accomplished without influencing their decision, by sharing the value of the profession. The purpose of this project was to develop and present a PowerPoint presentation to influence middle school, male students to improve their perceptions of nursing as a career …

Birth Weight And Body Mass Index Z-Score In Childhood Brain Tumors: A Cross-Sectional Study, Kuan-Wen Wang, Russell J De Souza, Adam Fleming, Donna L Johnston, Shayna M Zelcer, Shahrad Rod Rassekh, Sarah Burrow, Lehana Thabane, M Constantine Samaan

Paediatrics Publications

Children with brain tumors (CBT) are at higher risk of cardiovascular disease and type 2 diabetes compared to the general population, in which birth weight is a risk factor for these diseases. However, this is not known in CBT. The primary aim of this study was to explore the association between birth weight and body mass measures in CBT, compared to non-cancer controls. This is a secondary data analysis using cross-sectional data from the CanDECIDE study (n = 78 CBT and n = 133 non-cancer controls). Age, sex, and birth weight (grams) were self-reported, and confirmed through examination of the …

Epidemiology News, Georgia Southern University

Biostatistics, Epidemiology & Environmental Health Sciences: News & Publications (2011-2018)

• Georgia Southern Examines Epithelial Ovarian Cancer Mortality among Hispanic Women

A Multi-Functional View Of Moral Disengagement: Exploring The Effects Of Learning The Consequences, C. Justice Tillman, Katerina Gonzalez, Marilyn V. Whitman, Wayne S. Crawford, Anthony C. Hood

Publications and Research

This paper takes us beyond the unethical act and explores the use of moral disengagement as a multi-stage, multi-functional regulatory, and coping mechanism that not only allows individuals to engage in unethical behavior, but also manage the negative emotions (i.e., guilt and shame) from learning the consequences of such behavior. A resource-based lens is applied to the moral disengagement process, suggesting that individuals not only morally disengage prior to committing an unethical act in order to conserve their own resources, but also morally disengage as a coping mechanism to reduce emotional duress upon learning of the consequences of their actions, …

Factors Deterring Dentistry, Medical, Pharmacy, And Social Science Undergraduates From Pursuing Nursing As A Healthcare Career: A Cross-Sectional Study In An Asian University, Ling Ting Wu, Wenru Wang, Eleanor Holroyd, Violeta Lopez, Sok Ying Liaw

School of Nursing & Midwifery, East Africa

Background: Globally more registered nurses need to be recruited to meet the needs of aging populations and increased co-morbidity. Nursing recruitment remains challenging when compared to other healthcare programs. Despite healthcare students having similar motivation in joining the healthcare industry, many did not consider nursing as a career choice. This study aims to identify the deterrents to choosing nursing among healthcare undergraduates by examining the differences in the factors influencing healthcare career choices and nursing as a career choice.

Methods: A cross sectional study was conducted using a 35-parallel items instrument known as Healthcare Career Choice and Nursing Career Choice …

Inductive And Deductive: Ambiguous Labels In Qualitative Content Analysis, Mohammad Reza Armat, Abdolghader Assarroudi, Mostafa Rad, Hassan Sharifi, Abbas Heydari

The Qualitative Report

The propounded dualism in Content Analysis as quantitative and qualitative approaches is widely supported and justified in nursing literature. Nevertheless, another sort of dualism is proposed for Qualitative Content Analysis, suggesting the adoption of "inductive" and/or "deductive" approaches in the process of qualitative data analysis. These approaches have been referred and labelled as "inductive" or "conventional"; and "deductive" or "directed" content analysis in the literature. Authors argue that these labels could be fallacious, and may lead to ambiguity; as in effect, both approaches are employed with different dominancy during the process of any Qualitative Content Analysis. Thus, authors suggest more …

Data Saturation: The Mysterious Step In Grounded Theory Method, Khaldoun M. Aldiabat, Carole-Lynne Le Navenec

The Qualitative Report

The aim of this paper is to provide a discussion that is broad in both depth and breadth, about the concept of data saturation in Grounded Theory. It is expected that this knowledge will provide a helpful resource for (a) the novice researcher using a Grounded Theory approach, or for (b) graduate students currently enrolled in a qualitative research course, and for (c) instructors who teach or supervise qualitative research projects. The following topics are discussed in this paper: (1) definition of data saturation in Grounded Theory (GT); (2) factors pertaining to data saturation; (3) factors that hinder data saturation; …

Community Health News, Georgia Southern University

Health Policy & Community Health: News & Publications (2011-2018)

• Georgia Southern Examines Physician Attitudes

An Examination Of Factors That Affect The Utilization Of Mental Health Services By Adolescents, Nichole A. Murray

USF Tampa Graduate Theses and Dissertations

Mental disorders among adolescents are on the rise and are among the most common chronic conditions, constituting a national epidemic. Prevalence rates indicate that 20–40% of the adolescent population in the U.S. suffers from emotional or behavioral difficulties significant enough to lead to functional impairment. Further, estimates suggest that more than 20% of the adolescent population has a diagnosable mental disorder, which significantly impacts their functioning substantially at school, at home and in their communities. Despite national agendas to address the mental health needs of adolescents, studies suggest that approximately 50 percent of adolescents with mental health needs do not …

College Of Public Health News, Georgia Southern University

College of Public Health: News & Publications

• Georgia Southern Examines Epithelial Ovarian Cancer Mortality among Hispanic Women
• Georgia Southern Examines Georgia’s Critical Access Hospitals
• Georgia Southern Details a Sampling Scheme
• Georgia Southern Examines Physician Attitudes

Health Policy & Management News, Georgia Southern University

Health Policy & Community Health: News & Publications (2011-2018)

• Georgia Southern Examines Georgia’s Critical Access Hospital’s
• Georgia Southern Examines Epithelial Ovarian Cancer Mortality among Hispanic Women
• Georgia Southern Examines Physician Attitudes

The Santa Clara, 2018-01-25, Santa Clara University

The Santa Clara

No abstract provided.

Amyloid-Beta Solubility In The Treatment Of Alzheimer's Disease, Michael Paul Murphy

Molecular and Cellular Biochemistry Faculty Publications

No abstract provided.

The Use Of External Change Agents To Promote Quality Improvement And Organizational Change In Healthcare Organizations: A Systematic Review, Esra Alagoz, Ming-Yuan Chih, Mary Hitchcock, Randall Brown, Andrew Quanbeck

Health and Clinical Sciences Faculty Publications

Background: External change agents can play an essential role in healthcare organizational change efforts. This systematic review examines the role that external change agents have played within the context of multifaceted interventions designed to promote organizational change in healthcare-specifically, in primary care settings.

Methods: We searched PubMed, CINAHL, Cochrane, Web of Science, and Academic Search Premier Databases in July 2016 for randomized trials published (in English) between January 1, 2005 and June 30, 2016 in which external agents were part of multifaceted organizational change strategies. The review was conducted according to PRISMA guidelines. A total of 477 abstracts were identified …

Infection Of A Ventricular Septal Defect Patch With Acremonium Species, Nosheen Nasir, Kauser Jabeen, Joveria Farooqi, Binish Arif Sultan, Afia Zafar, Aamir Hameed Khan, Muneer Amanullah, Farheen Ali

Section of Internal Medicine

A ventricular septal defect (VSD) patch infection with Acremonium species isolated from vegetation and blood culture is described. Antifungal treatment was discontinued after 3 months and patient developed relapse. Surgery with prolonged oral voriconazole was instituted with recovery. We emphasize importance of surgery and prolonged therapy to treat such infections.

Pharmacists' Role In Harm Reduction: A Survey Assessment Of Kentucky Community Pharmacists' Willingness To Participate In Syringe/Needle Exchange, Amie Goodin, Amanda Fallin-Bennett, Traci Green, Patricia R. Freeman

Nursing Faculty Publications

Background: Pharmacists' role in harm reduction is expanding in many states, yet there are limited data on pharmacists' willingness to participate in harm reduction activities. This study assessed community pharmacists' willingness to participate in one harm reduction initiative: syringe/needle exchange.

Methods: In 2015, all Kentucky pharmacists with active licenses were emailed a survey that examined attitudes towards participation in syringe/needle exchange. Response frequencies were calculated for community pharmacist respondents. Ordinal logistic regression estimated the impact of community pharmacist characteristics and attitudes on willingness to provide clean needles/syringes to people who inject drugs and to dispose of used syringes/needles, where both …

A Gap In The United States Healthcare System: Physician Nutrition Education Knowledge And Application, Kristen Hicks

Showcase of Faculty Scholarly & Creative Activity

Physicians demonstrate an insufficiency in medical nutrition training, yet are expected to deliver nutrition counseling to patients with chronic disease. There is a clear understanding that unhealthy lifestyle behaviors (e.g. smoking, physical inactivity, poor diet) contribute to morbidity and mortality across the nation and worldwide. A preventable contribution to millions of deaths annually, which can be mitigated via brief nutrition and lifestyle counseling. Primary care is the ideal venue to deliver nutrition education and counseling, with a majority of all Americans regularly visiting their physician offices. With preventive medicine on the rise, is it imperative that a physician is proficient …

Ethics And Euthanasia, Nicole Marie Kasman

Biology: Student Scholarship & Creative Works

Illness is never easy to deal with and death is even harder whether it be for the patient, the patient's family, or the physician. Add into that, cases of sever and/or long-term suffering and people can begin wondering what there is to live for. Our animal companions have been able to escape pain via euthanasia for some time now but that same option is not generally available for their human counterparts. A suggested option for our terminally in is physician-assisted suicide. This has been met with a large amount of opposition, partly due to fear of promoting suicide, partly due …