Medicine and Health Sciences Commons^™

Family And Peer Groups’ Impact On Adolescent Marijuana Use, Brian Lunn

Research and Creative Activities Poster Day

Differential association theory explains that once definitions favoring deviant behavior become in excess of definitions favoring conforming, one is at an increased risk of acting deviant. This study uses survey data collected from high school students in Delaware to test hypotheses derived from differential association theory on student marijuana use.Consistent with theoretical expectations, the logistic regression results show that both parents’ and friends’ attitudes toward drug use as wrong and having a good relationship with one’s parents significantly reduce the likelihood of marijuana use, while living in an unstable home environment significantly increases the odds of marijuana use. Interestingly, results …

Evaluation Of Ct Perfusion Biomarkers Of Tumor Hypoxia, Qi Qi, Timothy Pok Chi Yeung, Ting-Yim Lee, Glenn Bauman, Cathie Crukley, Laura Morrison, Lisa Hoffman, Slav Yartsev

Anatomy and Cell Biology Publications

Background Tumor hypoxia is associated with treatment resistance to cancer therapies. Hypoxia can be investigated by immunohistopathologic methods but such procedure is invasive. A non-invasive method to interrogate tumor hypoxia is an attractive option as such method can provide information before, during, and after treatment for personalized therapies. Our study evaluated the correlations between computed tomography (CT) perfusion parameters and immunohistopathologic measurement of tumor hypoxia. Methods Wistar rats, 18 controls and 19 treated with stereotactic radiosurgery (SRS), implanted with the C6 glioma tumor were imaged using CT perfusion on average every five days to monitor tumor growth. A final CT …

Steroid Binding To Autotaxin Links Bile Salts And Lysophosphatidic Acid Signalling, Willem-Jan Keune, Jens Hausmann, Ruth Bolier, Dagmar Tolenaars, Andreas Kremer, Tatjana Heidebrecht, Robbie P. Joosten, Manjula Sunkara, Andrew J. Morris, Elisa Matas-Rico, Wouter H. Moolenaar, Ronald P. Oude Elferink, Anastassis Perrakis

Gill Heart & Vascular Institute Faculty Publications

Autotaxin (ATX) generates the lipid mediator lysophosphatidic acid (LPA). ATX-LPA signalling is involved in multiple biological and pathophysiological processes, including vasculogenesis, fibrosis, cholestatic pruritus and tumour progression. ATX has a tripartite active site, combining a hydrophilic groove, a hydrophobic lipid-binding pocket and a tunnel of unclear function. We present crystal structures of rat ATX bound to 7α-hydroxycholesterol and the bile salt tauroursodeoxycholate (TUDCA), showing how the tunnel selectively binds steroids. A structure of ATX simultaneously harbouring TUDCA in the tunnel and LPA in the pocket, together with kinetic analysis, reveals that bile salts act as partial non-competitive inhibitors …

Research Professionals’ Experience And Perspectives On Women’S Participation In Clinical Research, Anita Kurt Phd, Rn, Lauren Semler Ms, Matthew Meyers Bs, Bernadette Gl-Porter Bs, Samantha Myles Bs, Stephen W. Dusza Drph, Jeanne L. Jacoby Md, John C. Smulian Md, Mph

Department of Emergency Medicine

No abstract provided.

Athlete And Team Responses To Injury, Laura Heron

Honors Theses

No abstract provided.

Détection Des Microorganismes Par Fluorescence/Raman Uv Dans Des Aérosols, Des Suspensions Ou Sur Des Surfaces : Étude Exploratoire, Michaela Skulinova, Geneviève Marchand, Jean-François Gravel, Jacques Lavoie, Yves Cloutier

Rapports de recherche scientifique

Les microorganismes et leurs sous-produits sont présents dans tous les milieux de travail. Ils se retrouvent en suspension dans l’air, dans un liquide ou déposés sur des surfaces. Ils peuvent avoir des impacts importants sur les entreprises et la santé des travailleurs. Leur détection, à l’aide d’approches classiques faisant appel au dénombrement sur milieux gélosés, exige du temps et des ressources considérables. Cette étude vise à explorer une approche alternative et novatrice soit l’utilisation des signaux de fluorescence émis à différentes longueurs d’onde pour la détection et la différenciation de microorganismes en milieu de travail.

Un système mobile de …

Recruitment Feasibility Study For Reducing Postpartum Smoking Among Low-Income And Hispanic Women, Helai Hesham Md, Sandra L. Curet Md, Suresh G. Nair Md, Hope Kincaid Mph, Cph, Cynthia Beitler, Lourdes T. Matos, Clare Lenhart Phd, Mph

Department of Obstetrics & Gynecology

No abstract provided.

Recurring Ankle Injuries In Dancers, Alexis Jawny

Honors Theses

The purpose of this research, obtained from various Journals of Dance Medicine and Science, is to identify the cause of recurring ankle injuries in the dance community. Ankle injuries are the most common type of injury making up 50% of injuries in dancers. The main cause of recurring ankle injuries is improper diagnosing and then leading to the wrong treatment plan. The research focusses on how to prevent these improper diagnoses and what the dancer and specialty care professional (orthopedics, physical therapists, and rehabilitative medicine) can do to decrease the number of ankle injuries occurring and reoccurring in the dance …

The Psychological And Physical Rehabilitation Of Amputees, Victoria Ramos

Senior Honors Theses

Since physical therapy requires constant interaction with other people, it is a career that requires not only medical knowledge, but knowledge of the human psychology as well. A physical therapist may be well versed in recovery techniques, but how will he or she get the patient motivated if the patient is not motivated to begin with? Every person is different. Rehabilitation of amputees is a delicate process that requires significant work over an extended time period. Many factors are involved during the preoperative phase, as well as the postoperative phase. However, by being aware of the patient’s mental status and …

Health & Kinesiology News, Georgia Southern University

Health Sciences & Kinesiology: News & Publications (2015-2023)

• Dennis Receives Lori Mobley Groover Leadership Award

Proceedings - Wright State University Boonshoft School Of Medicine Eighth Annual Medical Student Research Symposium: Celebrating Medical Student Scholarship, Office Of Research Affairs, Boonshoft School Of Medicine

Medical Student Research Symposium Proceedings

The student abstract booklet is a compilation of abstracts from students' oral and poster presentations at Wright State University's Eighth Annual Boonshoft School of Medicine Medical Student Research Symposium held on April 13, 2016.

The Effect Of Reduced Carbohydrate Diet Education On Hemoglobin A1c In Patients With Type 2 Diabetes, Lauren Parker

Evidence-Based Practice Project Reports

Type 2 diabetes (T2D) is characteristically the result of modifiable risk factors, impacting the health and well being of all ethnic backgrounds across the lifespan. Research has indicated that despite the many risk factors associated with T2D, alterations in dietary macronutrient composition can lead to improvements in disease management and resultant complications. Therefore, the purpose of this evidence-based practice (EBP) project was to provide individuals with reduced carbohydrate (carb) diet education to promote greater glycemic control and reduce associated risk factors through macronutrient modification, specifically carb intake. An integration of the most current evidence obtained from the critically appraised literature …

Identification Of Kinematic And Kinetic Injury Risk Predictors In Division I Football Athletes, Corbin M. Rasmussen, Guilherme M. Cesar, Shinya Takahashi

UCARE: Research Products

biomechanical patterns and insufficiencies that may influence risk of ligamentous injury, such as an anterior cruciate ligament (ACL) tear. One kinematic pattern that has been identified as detrimental to ACL integrity is frontal plane knee collapse (valgus) during jumping and landing tasks.1 Inter-limb differences in force generation have also been connected to the occurrence of lower extremity injury.2 It is not known, however, whether these patterns contribute to the occurrence of lower extremity (LE) non-contact soft-tissue injury. The counter-movement vertical jump (CMVJ) is one way to simultaneously screen for knee collapse and asymmetrical force production patterns. This method was therefore …

Exertional Rhabdomyolysis In A 21-Year-Old, Healthy Female After Performing Three Sets Of The Biceps Curl Exercise To Failure With 30% 1rm: A Case Report, Noelle M. Yeo, Brianna D. Mckay, Amelia A. Miramonti, Nathaniel D. M. Jenkins, Joel T. Cramer

UCARE: Research Products

Background: The optimal resistance training program to elicit muscle hypertrophy has been consistently debated and researched. Although 3 sets of 10 repetitions at 70-80% of the 1-repetition maximum (1RM) is widely recommended, recent studies have shown that low-load (~30% 1RM), high-repetition (3 sets of 30-40 repetitions) resistance training can elicit similar muscular hypertrophy. Therefore, this type of resistance training has gained popularity, perhaps because less weight is lifted for a longer duration. In the process of testing this hypothesis in a research study in our laboratory, a subject diagnosed with exertional rhabdomyolysis after completing a single resistance training session …

Development Of A Temperature Sensitive Face Mask For Identification And Triage Of Febrile Patients, Annemarie Daecher, Flemming Forsberg, John R. Eisenbrey

Department of Radiology Posters

Abstract:

Many infectious diseases are most transmittable when the carrier is presenting with fever. We propose a disposable face mask that changes color as an indicator of fever to provide hospitals with a quick and inexpensive method for triaging infected patients while limiting exposure to others. Two blue thermochromatic dyes which transition to white at 89°F and 92°F were mixed with white paint and applied to 5 types of disposable face masks. During trials, a wearer either sat at rest or ran on a treadmill for 20 minutes and images were obtained every 5 minutes with a thermal camera to …

Dsg2 Increases Exosome Release And Enhances Egfr/C-Src Content: A Mechanism For Intercellular Mitogenic Effect, Andrew M. Overmiller, Jennifer A. Pierluissi, Peter J Wermuth, Ubaldo E. Martinez-Outshoorn, Md, Madalina Tuluc, Adam J. Luginbuhl, Joseph Curry, Larry A. Harshyne, James K. Wahl, Iii, Andrew P. South, M G Mahoney

Department of Dermatology and Cutaneous Biology Posters

Abstract:

Exosomes are nanoscale membrane-derived vesicles that are secreted by cancer cells and play a critical role in modulating the tumor microenvironment and disease pathogenesis. Dsg2, a desmosomal cadherin often overexpressed in skin malignancies including squamous cell carcinoma (SCC), can activate EGFR/c-Src signaling and promote oncogenesis. We sought to address the potential role of Dsg2 in exosome biogenesis and intercellular signaling in SCC. Here, purified exosomes from SCC cells and head/neck SCC patient sera were enriched with a processed 65 kDa membrane-associated C-terminal fragment of Dsg2. Cells overexpressing Dsg2 had increased exosome release and protein content and produced particles enriched …

Increasing Confidence In Evidence-Based Information Gathering For First Year Aud Students, Mickel Paris, Jiong Hu, Veronica Koo, Susanna Marshall, Gabriella Musacchia

University Libraries Librarian and Staff Presentations

Success of students in Doctor of Audiology programs largely depends on the ability of the learner to find and evaluate scholarly evidence. The purpose of this study is to measure changes in student information gathering confidence and behavior following training in evidence-based information gathering strategies. Results support the hypothesis that understanding foundational concepts in evidence-based practice (EBP) early in the first year of doctoral education allows the learner to gain confidence in information gathering and produce higher quality scholarly output.

Is The United States Prepared For A Major Zika Virus Outbreak?, Lawrence O. Gostin, James G. Hodge Jr.

Georgetown Law Faculty Publications and Other Works

Zika virus has emerged as a global public health crisis with active transmission in the Americas and Caribbean. The World Health Organization (WHO) declared a Public Health Emergency of International Concern (PHEIC), and recently WHO reported there is a scientific consensus that Zika is a cause of microcephaly and Guillain-Barré syndrome (GBS). In the U.S. the Centers for Disease Control and Prevention (CDC) activated its emergency operations center at its highest capacity. President Obama requested $1.86 billion in emergency funding. Shamefully, Congress has yet to appropriate the funding needed for Zika preparedness, and the President has had to reallocate Ebola …

A Comparative Analysis Of Attitudes Towards Women Physicians In Nineteenth Century Articles And Novels, Hannah White

Honors Theses

No abstract provided.

Conducting A Systematic Review Using Prisma Guidelines From A Student's Perspective, Malinda Hawkins, June Horowitz, Phd, Rn, Faan, Kathleen Black, Phd, Rnc

College of Nursing Faculty Papers & Presentations

RESEARCH QUESTION

To understand how to conduct a systematic review using PRISMA guidelines.

INTRODUCTION

The purpose of this presentation is to depict a student’s point of view about conducting a systematic review using PRISMA guidelines. We sought to determine what inflammatory markers have been identified for preeclampsia.

** A faculty team is conducting this systematic review and invited the student to participate.

Effect Of Breathing Apparatus On The Patterns Of Response For Physiological Variables During An Incremental Test To Exhaustion, Rachel Lechtenberger, Kristen C. Cochrane, Terry J. Housh

UCARE: Research Products

During running exercise, trained runners will utilize both nasal and oral breathing mechanisms. However, during most clinical running tests, the breathing apparatus blocks the nasal pathway, therefore only allowing oral breathing. It has been suggested that a breathing apparatus that allows both nasal and oral breathing may provide an environment that is more similar to running outside of a lab setting. PURPOSE: The purpose of this study was to examine the patterns of responses for physiological variables during an incremental treadmill running exercise test to exhaustion utilizing both a traditional mouth piece (MP) and breathing mask (MSK) apparatus. METHODS: …

Pharmaceutical Sciences Internship Bps 460, Robin Devin

Library Impact Statements

No abstract provided.

Pharmaceutical Sciences Internship Seminar Bps 461, Robin Devin

Library Impact Statements

No abstract provided.

The Connectivity Domain: Analyzing Resting State Fmri Data Using Feature-Based Data-Driven And Model-Based Methods, Armin Iraji, Vince D. Calhoun, Natalie M. Wiseman, Esmaeil Davoodi-Bojd, Mohammad R. N. Avanaki, Zhifeng Kou

Biomedical Engineering Faculty Research Publications

Spontaneous fluctuations of resting state functional MRI (rsfMRI) have been widely used to understand the macro-connectome of the human brain. However, these fluctuations are not synchronized among subjects, which leads to limitations and makes utilization of first-level model-based methods challenging. Considering this limitation of rsfMRI data in the time domain, we propose to transfer the spatiotemporal information of the rsfMRI data to another domain, the connectivity domain, in which each value represents the same effect across subjects. Using a set of seed networks and a connectivity index to calculate the functional connectivity for each seed network, we transform data into …

Healthy Living An In-Depth Look, Nina Radcliff, Md, Kristin Detterline

Jefferson Sleep Disorders Center in the News

Features Dr. Ritu Grewal, pulmonologist and attending physician at Jefferson Sleep Disorder Center Women's Program.

The Unmet Need For Care: Vulnerability Among Older Adults, Rebecca K. Glauber, Melissa Day

Carsey Publications

In this brief, authors Rebecca Glauber and Melissa Day explore factors that exacerbate the unmet need for care among the noninstitutionalized older population and seek to deter­mine who is likely to need care but go without. They find that unmarried individuals and those who live alone are more likely than others to need care but not receive it. These older adults are frail, have difficulty meet­ing their daily needs, and do not have family members or friends to whom to turn in times of need. This group of vulnerable older adults requires an array of social supports.

Stress In Newborn As Measuered By Salivary Cortisol: Determing Normal Values, Lee Tucker

Research Horizons Day Posters

No abstract provided.

Pretty Nails, Crooked Nose: Air Quality In Nail Salons, Rebecca Stillwell

Research Horizons Day Posters

No abstract provided.

The Challenges Of Collecting Qualitative Data In A High Census Hospital Unit, Kristen Bertrand

Research Horizons Day Posters

No abstract provided.

Nursing Students' Concerns And Exoeriences Toward End-Of-Life Care: A Mixed Methods Study Using Simulation, Patricia Cosby

Research Horizons Day Posters

No abstract provided.