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2016

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Articles 10861 - 10890 of 12713

Full-Text Articles in Medicine and Health Sciences

Effectiveness Of An Interprofessional Education Event For Graduate Health Professional Students, Lisa J. Knecht-Sabres, James F. Gunn, Christine Conroy, Sarah E. Getch, Susan M. Cahill, Michelle M. Lee, Mae J. Ciancio, Jayne Jaskolski, Lisa Palmisano, Kolbrun Kristjansdottir Jan 2016

Effectiveness Of An Interprofessional Education Event For Graduate Health Professional Students, Lisa J. Knecht-Sabres, James F. Gunn, Christine Conroy, Sarah E. Getch, Susan M. Cahill, Michelle M. Lee, Mae J. Ciancio, Jayne Jaskolski, Lisa Palmisano, Kolbrun Kristjansdottir

Internet Journal of Allied Health Sciences and Practice

ABSTRACT

Purpose: The purpose of this study was to investigate the impact of a single, optional, half-day, interprofessional education (IPE) event for a myriad of graduate-level health professional students (n=44) at a university in Illinois, USA. Methods: The researchers in this study examined students’ performance on two out of six of the domains on the Interprofessiomnal Collaborator Assessment Rubric (ICAR): Roles and Responsibilities and Communication Strategies. This study also investigated quantitative and qualitative findings related to student perceptions regarding this IPE opportunity. Results: Results indicated that students met or exceeded the minimum competency for the ranking of “developing” for …


Clinical Educator And Student Perceptions Of Ipad™ Technology To Enhance Clinical Supervision: The Electronically-Facilitated Feedback Initiative (Effi), Suzanne J. Snodgrass, Darren Rivett, Scott Farrell, Kyle Ball, Samantha E. Ashby, Catherine L. Johnston, Kim Nguyen, Trevor Russell Jan 2016

Clinical Educator And Student Perceptions Of Ipad™ Technology To Enhance Clinical Supervision: The Electronically-Facilitated Feedback Initiative (Effi), Suzanne J. Snodgrass, Darren Rivett, Scott Farrell, Kyle Ball, Samantha E. Ashby, Catherine L. Johnston, Kim Nguyen, Trevor Russell

Internet Journal of Allied Health Sciences and Practice

Purpose: Growing demands placed upon healthcare systems require more health professionals to be trained. Clinical placement education is an integral component of health professional training, however accommodating increasing numbers of student placements is a challenge for health services. Personal digital assistants such as iPads™ may assist in delivery of clinical education, by facilitating transfer of knowledge and skills from clinical educators to health professional students, however such an initiative has not been formally investigated. The present study sought to explore perceptions of clinical educators and allied health students regarding the impact of an iPad™-based feedback delivery system on student …


Commentary: See Me, Feel Me, Touch Me, Heal Me, Peter G. Holub Jan 2016

Commentary: See Me, Feel Me, Touch Me, Heal Me, Peter G. Holub

Internet Journal of Allied Health Sciences and Practice

The title of my commentary is from the rock opera Tommy. Tommy doesn’t ask for a high-tech medical cure for his disease. He isn’t interested in prescription drugs. He craves the simple human touch - a low-tech form of caring that has no negative side-effects. The healing power of the human touch is validated by scientific research. So, other than the fact that it doesn’t have an ICD-10 medical billing code, why don’t doctors and other caregivers like to touch their patients?


Opportunities And Challenges In The Use Of An External Interprofessional Reviewing Body In A Curricular Review Process In A Doctor Of Physical Therapy Curriculum, Jill Fitzgerald, Kelly Hawthorne Jan 2016

Opportunities And Challenges In The Use Of An External Interprofessional Reviewing Body In A Curricular Review Process In A Doctor Of Physical Therapy Curriculum, Jill Fitzgerald, Kelly Hawthorne

Internet Journal of Allied Health Sciences and Practice

Purpose: The purpose of this article is to describe the opportunities and challenges of a curricular review process in an entry-level doctor of physical therapy geriatric curriculum. The curricular review process utilized an external interprofessional reviewing body, in conjunction with an established internal curricular reviewing body, to determine inclusion of Essential Competencies in order to prepare students for best clinical practice in the care of the older adult. Method: The methodology of our curricular review process included both internal and external reviewing bodies but the intent of this article is to highlight how the review process was implemented including an …


Prevalence Of Risk Factors For Metabolic Syndrome In Uninsured Hispanic Adults From Low Income Communities In El Paso, Texas, Juan Antonio Aguilera Jan 2016

Prevalence Of Risk Factors For Metabolic Syndrome In Uninsured Hispanic Adults From Low Income Communities In El Paso, Texas, Juan Antonio Aguilera

Open Access Theses & Dissertations

Metabolic syndrome (MetS) consists of a group of associated risk factors for cardiovascular disease and other related chronic diseases. In the U.S. it is estimated that nearly 35% of the adult population have metabolic syndrome. According to National Institutes of Health (NIH) guidelines risk factors for developing MetS include large waistline, high blood pressure, high triglyceride level, low high density lipoprotein (HDL) cholesterol level, and elevated fasting blood glucose level. The goal of this study was to investigate the prevalence of risk factors for MetS among uninsured, low socioeconomic status adult Hispanics in El Paso, Texas. The study population resided …


Histological And Behavioral Consequences Of Repeated Mild Traumatic Brain Injury In Mice, Amanda Nicholle Bolton Hall Jan 2016

Histological And Behavioral Consequences Of Repeated Mild Traumatic Brain Injury In Mice, Amanda Nicholle Bolton Hall

Theses and Dissertations--Physiology

The majority of the estimated three million traumatic brain injuries that occur each year are classified as “mild” and do not require surgical intervention. However, debilitating symptoms such as difficulties focusing on tasks, anxiety, depression, and visual deficits can persist chronically after a mild traumatic brain injury (TBI) even if an individual appears “fine”. These symptoms have been observed to worsen or be prolonged when an individual has suffered multiple mild TBIs. To test the hypothesis that increasing the amount of time between head injuries can reduce the histopathological and behavioral consequences of repeated mild TBI, a mouse model of …


Health-Related Quality Of Life In Athletes: A Systematic Review With Meta-Analysis, Megan N. Houston, Matthew C. Hoch, Johanna M. Hoch Jan 2016

Health-Related Quality Of Life In Athletes: A Systematic Review With Meta-Analysis, Megan N. Houston, Matthew C. Hoch, Johanna M. Hoch

Rehabilitation Sciences Faculty Publications

Context: Assessment of health-related quality of life (HRQOL) after injury is important. Differences in HRQOL between nonathletes and athletes and between injured and uninjured athletes have been demonstrated; however, the evidence has not been synthesized.

Objective: To answer the following questions: (1) Does HRQOL differ among adolescent and collegiate athletes and nonathletes? (2) Does HRQOL differ between injured adolescent and collegiate athletes or between athletes with a history of injury and uninjured athletes or those without a history of injury?

Data Sources: We systematically searched CINAHL, MEDLINE, SPORTDiscus, and PubMed. A hand search of references was also conducted.

Study Selection: …


Grant Application: Compassionate Touch Short Film, Jessfor Baugh, Riddhi Daftary Jan 2016

Grant Application: Compassionate Touch Short Film, Jessfor Baugh, Riddhi Daftary

Compassionate Touch

IPEC Mini-grant application for funding of UNE student project Compassionate Touch.UNE Dental Medicine students collaborated with Creative and Fine Arts faculty and Dental Medicine faculty to create the film Compassionate Touch, focusing on five stages associated with anxious dental patients, as depicted through artwork, interprofessional interviews and scholarly sources. The film highlights the current understanding and management of the dental needs for high fear patients before, during, and after their visit to the dentist, and how interprofessional health care providers can assist patients to achieve quality patient-centered care.


Compassionate Touch Artworks: Listen To Identify, Validation, Everyone Has A Story, Not Alone, The Compassionate Touch, Jessfor Baugh Jan 2016

Compassionate Touch Artworks: Listen To Identify, Validation, Everyone Has A Story, Not Alone, The Compassionate Touch, Jessfor Baugh

Compassionate Touch

Artworks created during the course of UNE student project Compassionate Touch. UNE Dental Medicine students collaborated with Creative and Fine Arts faculty and Dental Medicine faculty to create the film Compassionate Touch, focusing on five stages associated with anxious dental patients, as depicted through artwork, interprofessional interviews and scholarly sources. The film highlights the current understanding and management of the dental needs for high fear patients before, during, and after their visit to the dentist, and how interprofessional health care providers can assist patients to achieve quality patient-centered care.

Artwork Descriptions

First image is a photograph of the five artworks …


Comparison Of Risk Factors And Survival Of Type 1 And Type Ii Endometrial Cancers, Tahira Y. Malik, Uzma Chishti, Aliya Aziz, Irfan Sheikh Jan 2016

Comparison Of Risk Factors And Survival Of Type 1 And Type Ii Endometrial Cancers, Tahira Y. Malik, Uzma Chishti, Aliya Aziz, Irfan Sheikh

Department of Obstetrics & Gynaecology

Objective: To compare risk factors and progression free survival of type 1 & 2 endometrial cancers.
Methods: A retrospective analysis of 149 patients with early stage endometrial carcinoma treated between 1997 and 2012 in Aga Khan University Hospital, Karachi was performed.
Results: A total of 149 patients were analyzed. Type I tumors accounted for 92% of cases in the study while 8% were type II tumors. The mean age, BMI, parity, co-morbidities (hypertension & Diabetes), family history and history of polycystic disease were comparable in both groups. Overall better survival (113 Vs 24 months) was observed for type I endometrial …


Brief Report: A Mobile Application To Treat Prosodic Deficits In Autism Spectrum Disorder And Other Communication Impairments: A Pilot Study, Elizabeth Schoen Simmons, Rhea Paul, Frederick Shic Jan 2016

Brief Report: A Mobile Application To Treat Prosodic Deficits In Autism Spectrum Disorder And Other Communication Impairments: A Pilot Study, Elizabeth Schoen Simmons, Rhea Paul, Frederick Shic

Communication Disorders Faculty Publications

This study examined the acceptability of a mobile application, SpeechPrompts, designed to treat prosodic disorders in children with ASD and other communication impairments. Ten speech-language pathologists (SLPs) in public schools and 40 of their students, 5-19 years with prosody deficits participated. Students received treatment with the software over eight weeks. Pre- and post-treatment speech samples and student engagement data were collected. Feedback on the utility of the software was also obtained. SLPs implemented the software with their students in an authentic education setting. Student engagement ratings indicated students' attention to the software was maintained during treatment. Although more testing is …


A Review Of Factors Contributing To The Shortage Of Palliative Care Service For Adolescent And Young Adult Oncology Patients, Erin K. Harper Jan 2016

A Review Of Factors Contributing To The Shortage Of Palliative Care Service For Adolescent And Young Adult Oncology Patients, Erin K. Harper

Antioch University Dissertations & Theses

Adolescent and young adult oncology (patients aged 15–39 years old) is an emerging group of patients that are recognized to have distinctive qualities concerning their cancer treatment, including intensified psychosocial needs compared to their adult and child counterparts (Bleyer, 2012). The quality of life for adolescent and young adults during and after cancer treatment is disproportionally worse than what is reported by adults and children and the incidence of cancer in this population is steadily growing (Bleyer, 2011, 2012; Pritchard, Cuvelier, Harlos, & Barr, 2011; Rosenberg & Wolfe, 2013; Siegel, Naishadham, & Jemal, 2013; Wein, Pery, & Zer, 2011). Palliative …


The Relation Between Serum Cathepsin D Level And Carotid Intima-Media Thickness In Nondiabetic Hypertensive Patients, Ni̇hal Özkayar, Fatma Akyel, Ayşe Nurdan Barça, Serhan Vahi̇t Pi̇şki̇npaşa, Turan Turhan, İhsan Ateş, Fati̇h Dede Jan 2016

The Relation Between Serum Cathepsin D Level And Carotid Intima-Media Thickness In Nondiabetic Hypertensive Patients, Ni̇hal Özkayar, Fatma Akyel, Ayşe Nurdan Barça, Serhan Vahi̇t Pi̇şki̇npaşa, Turan Turhan, İhsan Ateş, Fati̇h Dede

Turkish Journal of Medical Sciences

Background/aim: We aimed to investigate the relation between carotid intima-media thickness (CIMT) and serum cathepsin D level in hypertensive patients. Materials and methods: This was a cross-sectional study of 74 hypertensive patients (22 males and 52 females, with a mean age of 51.86 ± 11.75 years). Serum levels of cathepsin D were measured with an enzyme-linked immunosorbent assay. CIMT measurements were taken from 3 different points: right and left common carotid arteries, bifurcation, and the first 2 cm of the internal carotid artery. Mean CIMT was calculated by averaging the measurements taken 3 times from each carotid artery. Results: Mean …


Analysis Of The Hip Fracture Records Of A Central Training And Research Hospital By Selected Characteristics, Deni̇z Çankaya, Burak Yoldaş, Eli̇f Çankaya, Yalçin Çakir, Cemal Aydin, Abdullah Yalçin Tabak Jan 2016

Analysis Of The Hip Fracture Records Of A Central Training And Research Hospital By Selected Characteristics, Deni̇z Çankaya, Burak Yoldaş, Eli̇f Çankaya, Yalçin Çakir, Cemal Aydin, Abdullah Yalçin Tabak

Turkish Journal of Medical Sciences

Background/aim: Despite the importance of hip fractures, very few studies have assessed their epidemiological characteristics in Turkey. The aim of this study was to evaluate the frequency and demography of hip fractures from the recent data of a central training and research hospital. Materials and methods: In this descriptive study, we identified hip fracture cases between 2009 and 2013. The age, sex, region, injury pattern, and calendar year for all patients were evaluated. Results: Among the 687 patients (488 women, 199 men) described in our clinic's records, 122, 131, 144, 138, and 154 patients applied with hip fractures from the …


Clinical Features Of Infants Treated For Severe Retinopathy Of Prematurity: 8-Yearstudy From A Large Tertiary Neonatal Intensive Care Unit In Turkey, Zühal Özen Tunay, Özdemi̇r Özdemi̇r, Damla Ergi̇ntürk Acar, İkbal Seza Petri̇çli̇, Şeri̇fe Suna Oğuz Jan 2016

Clinical Features Of Infants Treated For Severe Retinopathy Of Prematurity: 8-Yearstudy From A Large Tertiary Neonatal Intensive Care Unit In Turkey, Zühal Özen Tunay, Özdemi̇r Özdemi̇r, Damla Ergi̇ntürk Acar, İkbal Seza Petri̇çli̇, Şeri̇fe Suna Oğuz

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to report the gestational age (GA) and birth weight (BW) distribution of premature babies who needed treatment for retinopathy of prematurity (ROP) and to assess the timing of the treatment. Materials and methods: The records of 9008 infants who were screened for ROP were examined and 556 infants who underwent laser therapy for ROP were reviewed. Sex, GA, BW, postnatal age, and postmenstrual (PM) age at the time of laser therapy were recorded. The babies were classified as in-born (Group 1) and out-born infants (Group 2). Results: The mean GA was 27.3 weeks …


Recurrent Dilatation In Resistant Benign Esophageal Strictures: Timing Is Significant, Yasemi̇n Bi̇lgi̇n Büyükkarabacak, Ayşen Taslak Şengül, Mehmet Gökhan Pi̇rzi̇renli̇, Ahmet Başoğlu Jan 2016

Recurrent Dilatation In Resistant Benign Esophageal Strictures: Timing Is Significant, Yasemi̇n Bi̇lgi̇n Büyükkarabacak, Ayşen Taslak Şengül, Mehmet Gökhan Pi̇rzi̇renli̇, Ahmet Başoğlu

Turkish Journal of Medical Sciences

Background/aim: Benign esophageal strictures are frequently encountered pathologies occurring due to various reasons. Repeated dilatations may be needed, particularly in resistant strictures. This study aimed to evaluate patients who underwent repeated dilatations in our clinic due to resistant esophageal strictures. Materials and methods: Sixteen patients who underwent multiple dilatations in our clinic with the diagnosis of resistant benign esophageal stricture between 2007 and 2014 were studied for age, sex, etiology, symptoms, complications, number of dilatations, and intervals between dilatations. Under general anesthesia, all patients underwent dilatation with Savary-Gilliard bougie dilators with the help of rigid esophagoscopy. Results: In 10 of …


Evaluation Of Intraabdominal Hypertension And Genitofemoral Nerve Motor Conduction, Özlem Boybeyi̇, Elem İnal, Yasemi̇n Dere Günal, Mustafa Kemal Aslan, Gülümser Aydin, Tutku Soyer Jan 2016

Evaluation Of Intraabdominal Hypertension And Genitofemoral Nerve Motor Conduction, Özlem Boybeyi̇, Elem İnal, Yasemi̇n Dere Günal, Mustafa Kemal Aslan, Gülümser Aydin, Tutku Soyer

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to electrophysiologically evaluate the effect of increased intraabdominal pressure (IAP) on genitofemoral nerve (GFN) motor conduction. Materials and methods: Seven Wistar albino rats were included. After anesthetization, latency and duration of GFN conduction was recorded with a needle-probe at rest. IAP was increased to 15 mmHg by insufflating atmospheric air with a percutaneous intraperitoneal needle. At 30 min of IAP, GFN motor conduction was recorded. Abdominal pressure was then increased to 20 mmHg. At 60 min, GFN motor conduction was recorded again. The consecutive recordings of latency and duration of GFN conduction (rest, …


Frequency Of Twelve Carcinogenic Human Papilloma Virus Types Among Women From The South Backa Region, Vojvodina, Serbia, Gordana Kovacevic, Natasa Nikolic, Aleksandra Jovanovic-Galovic, Ivana Hrnjakovic-Cvjetkovic, Dusan Vuleta, Aleksandra Patic, Jelena Radovanov, Vesna Milosevic Jan 2016

Frequency Of Twelve Carcinogenic Human Papilloma Virus Types Among Women From The South Backa Region, Vojvodina, Serbia, Gordana Kovacevic, Natasa Nikolic, Aleksandra Jovanovic-Galovic, Ivana Hrnjakovic-Cvjetkovic, Dusan Vuleta, Aleksandra Patic, Jelena Radovanov, Vesna Milosevic

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to determine the presence and age distribution of different oncogenic human papilloma virus (HPV) types in women in the South Backa region and its relationship to Pap results. Materials and methods: In a group of 1087 women with normal and abnormal cytology, the commercial HR HPV Real-TM kit (Sacace Biotechnologies, Italy) was used. Results: Overall, 50.5% of the women were HPV positive. The presence of HPV types 18, 31, 51, and 58 was significantly influenced by age, while the presence of HPV types 16 and 45 was significantly influenced by cervical cytology. Results …


The Utility Of Ebus-Tbna In Mediastinal Or Hilar Lymph Node Evaluation In Extrapulmonary Malignancy, Onur Fevzi̇ Erer, Ceyda Anar, Serhat Erol, Seri̇r Özkan Jan 2016

The Utility Of Ebus-Tbna In Mediastinal Or Hilar Lymph Node Evaluation In Extrapulmonary Malignancy, Onur Fevzi̇ Erer, Ceyda Anar, Serhat Erol, Seri̇r Özkan

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to determine the diagnostic performance of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in the diagnosis of mediastinal and hilar lymph nodes (LNs) in patients with known extrapulmonary malignancy. Materials and methods: Between March 2011 and August 2013, 378 EBUS-TBNA procedures were performed. Sixty-three (16.6%) of these were performed on known extrapulmonary malignancy patients. Results: There were 28 male and 35 female patients, with median ages of 65 years (min-max: 53-87) and 57 years (min-max: 39-76), respectively. From the 63 cases, 138 lymph nodes (LNs) were sampled with EBUS-TBNA (median: 2 LNs/patient; min-max: 1-4). …


Investigation Of Ischemia-Modified Albumin Levels And Some Atherosclerosis-Related Serum Parameters In Patients With Diabetic Foot, Sabahatti̇n Muhtaroğlu, Di̇dem Barlak Keti̇, Kürşad Ünlühi̇zarci Jan 2016

Investigation Of Ischemia-Modified Albumin Levels And Some Atherosclerosis-Related Serum Parameters In Patients With Diabetic Foot, Sabahatti̇n Muhtaroğlu, Di̇dem Barlak Keti̇, Kürşad Ünlühi̇zarci

Turkish Journal of Medical Sciences

Background/aim: To investigate serum ischemia-modified albumin (IMA), oxidized low-density lipoprotein (ox-LDL) levels, and paraoxonase 1 (PON1) activity in patients with diabetic foot. Materials and methods: Thirty patients with diabetes mellitus (DM), 30 patients with diabetic foot (29 and 27 of these patients had type 2 DM, respectively), and 30 healthy volunteers as the control group were included in the study. The patients with diabetic foot were divided into 2 groups, as those who had or had not undergone lower extremity amputation. Serum PON1 activity, ox-LDL, and IMA levels were measured. Results: Serum PON1 activity was lower (P < 0.05) and ox-LDL levels were higher (P < 0.05) in the diabetic foot group than in the control and diabetes groups. Albumin-adjusted IMA values were higher (P < 0.001) in the diabetic foot group compared to the diabetes group. The postamputation levels of IMA were decreased compared to the preamputation condition (P < 0.05). Conclusion: The low activity of PON1 and the high levels of ox-LDL and IMA may play an important role in the pathogenesis of diabetic foot. The use of these parameters in the follow-up of patients with DM may prevent the development of diabetic foot. In order to reach a definitive judgment, further studies with a larger number of subjects are necessary.


Impact Of Antimicrobial Drug Restrictions On Doctors? Behaviors, Oğuz Karabay, Sali̇h Hoşoğlu, Ertuğrul Güçlü, Şeri̇fe Akalin, Fatma Aybala Altay, Emsal Aydin, Bahadir Ceylan, Aygül Çeli̇k, İlhami̇ Çeli̇k, Tuna Demi̇rdal, Kezi̇ban Demi̇rli̇, Nuretti̇n Erben, Ünal Erkorkmaz, Serpi̇l Erol, Ömer Evi̇rgen Jan 2016

Impact Of Antimicrobial Drug Restrictions On Doctors? Behaviors, Oğuz Karabay, Sali̇h Hoşoğlu, Ertuğrul Güçlü, Şeri̇fe Akalin, Fatma Aybala Altay, Emsal Aydin, Bahadir Ceylan, Aygül Çeli̇k, İlhami̇ Çeli̇k, Tuna Demi̇rdal, Kezi̇ban Demi̇rli̇, Nuretti̇n Erben, Ünal Erkorkmaz, Serpi̇l Erol, Ömer Evi̇rgen

Turkish Journal of Medical Sciences

Background/aim: Broad-spectrum antibiotics have become available for use only with the approval of infectious disease specialists (IDSs) since 2003 in Turkey. This study aimed to analyze the tendencies of doctors who are not disease specialists (non-IDSs) towards the restriction of antibiotics. Materials and methods: A questionnaire form was prepared, which included a total of 22 questions about the impact of antibiotic restriction (AR) policy, the role of IDSs in the restriction, and the perception of this change in antibiotic consumption. The questionnaire was completed by each participating physician. Results: A total of 1906 specialists from 20 cities in Turkey participated …


Effects Of Immunosuppressive Drugs On Oral Mucosa In Patients With Behçet?S Disease: Cytomorphological And Cytopathological Assessment, Eda Di̇yarbakir, Adem Kara, Sadullah Keleş, Jale Selli̇, Handan Bi̇len, Ni̇lnur Eyerci̇, Necmetti̇n Akdeni̇z, Orhan Ateş, Hasan Doğan Jan 2016

Effects Of Immunosuppressive Drugs On Oral Mucosa In Patients With Behçet?S Disease: Cytomorphological And Cytopathological Assessment, Eda Di̇yarbakir, Adem Kara, Sadullah Keleş, Jale Selli̇, Handan Bi̇len, Ni̇lnur Eyerci̇, Necmetti̇n Akdeni̇z, Orhan Ateş, Hasan Doğan

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to investigate cytomorphological and cytopathological changes in oral exfoliated smears collected from immunosuppressed patients with Behçet's disease (BD) using stereological methods. Materials and methods: For cytomorphometric analysis, mucosal cell smears were obtained from the buccal mucosa and the floor of the mouths of BD patients treated with immunosuppressive drugs and from healthy volunteers. All mucosal smears from the patients and the healthy volunteers were stained using the Papanicolaou method and examined cytopathologically under light microscopy and cytomorphologically via the stereological nucleator method. Results: The cytomorphological analysis revealed 3 types of mucosal cells, with …


Cost-Effectiveness Analysis Of Pemetrexed And Gemcitabine Treatment For Advanced Nonsmall Cell Lung Cancer In Turkey, Pinar Yalçin Balçik, Bayram Şahi̇n Jan 2016

Cost-Effectiveness Analysis Of Pemetrexed And Gemcitabine Treatment For Advanced Nonsmall Cell Lung Cancer In Turkey, Pinar Yalçin Balçik, Bayram Şahi̇n

Turkish Journal of Medical Sciences

Background/aim: The purpose of the study is to determine the cost-effectiveness of the chemotherapy medications that contain gemcitabine and pemetrexed, which are used in the treatment of advanced nonsmall cell lung cancer (NSCLC). Materials and methods: The study evaluated the effectiveness and cost of platinum-based pemetrexed and gemcitabine treatments as the first-line treatment of advanced NSCLC with the use of the Markov model, and from the perspective of the Social Security Institution. NSCLC costs calculated on the basis of experts' opinions and the effectiveness values calculated by administering the EQ-5D questionnaire to the patients were analyzed. All direct medical costs …


Effects And Mechanisms Of Curcumin On The Hemodynamic Variablesof Isolated Perfused Rat Hearts, Erkan Kilinç, Zi̇ya Kaygisiz, Bedri̇ Seli̇m Benek, Kenan Gümüşteki̇n Jan 2016

Effects And Mechanisms Of Curcumin On The Hemodynamic Variablesof Isolated Perfused Rat Hearts, Erkan Kilinç, Zi̇ya Kaygisiz, Bedri̇ Seli̇m Benek, Kenan Gümüşteki̇n

Turkish Journal of Medical Sciences

Background/aim: There is no information on the dose-response relationship of curcumin on the hemodynamic variables of the heart at the organ level in isolated perfused rat hearts. We aimed to investigate the effects and mechanisms of curcumin on the hemodynamic variables of isolated perfused rat hearts. Materials and methods: Rats were randomly divided into 9 groups. The isolated rat heart was retrogradely perfused with modified Krebs-Henseleit solution. After the stabilization period, each group was administered one of the following treatments for 25 min: saline, dimethyl sulfoxide, and curcumin (0.2 μM, 1 μM, and 5 μM); atropine (1 μM); atropine (1 …


Intrabone Marrow Injection Enhances Placental Mesenchymal Stem Cellmediated Support Of Hematopoiesis In Mice, Ya Hong Yuan, Chun Fang Zhou, Zhi Yong Lu, Xiao Li Wang, Yan Ding, Dongsheng Li Jan 2016

Intrabone Marrow Injection Enhances Placental Mesenchymal Stem Cellmediated Support Of Hematopoiesis In Mice, Ya Hong Yuan, Chun Fang Zhou, Zhi Yong Lu, Xiao Li Wang, Yan Ding, Dongsheng Li

Turkish Journal of Medical Sciences

Background/aim: In order to determine the synergistic effects of human placental mesenchymal stem cells (PMSCs) on hematopoiesis in vivo, we compared the intrabone marrow injection (IBMI) with the conventional intravenous injection (IVI). Materials and methods: C57BL/6 recipient mice conditioned with lethal doses of irradiation were transplanted with bone marrow mononuclear cells (MNCs) and bone marrow-derived mesenchymal stem cells (BMSCs) from BALB/c mice by IBMI or IVI. NOD/SCID recipient mice conditioned with sublethal doses of irradiation were transplanted with human umbilical cord blood MNCs (UCB-MNCs) and PMSCs by IBMI or IVI. Results: The number of hematopoietic cells was significantly higher in …


The Effect Of Proanthocyanidin On Formaldehyde-Induced Toxicity In Rat Testes, Eni̇s Uluçam, Elvan Bakar Jan 2016

The Effect Of Proanthocyanidin On Formaldehyde-Induced Toxicity In Rat Testes, Eni̇s Uluçam, Elvan Bakar

Turkish Journal of Medical Sciences

Background/aim: This study investigated the effect of proanthocyanidin (PA) against formaldehyde (FA)-induced lipid peroxidation damage and morphological changes in rat testes. Materials and methods: Twenty-one Wistar albino rats were randomized into 3 groups: control, FA, and FA + PA groups. Plasma and tissue malondialdehyde (MDA) and total sialic acid (TSA) levels were measured. Testes tissues were observed by light and electron microscopy. Results: TSA (plasma and tissue) levels decreased and MDA (plasma) significantly increased (P < 0.05) in rats treated with FA compared to the controls. Tissue MDA levels were not significantly different. Several necrotic changes were observed in testes tissues by light and electron microscopy. Disordering in epithelia of seminiferous tubules, vacuolization between germinal epithelium cells, and separated basement membranes were observed by light microscope. Immunopositivity in Leydig cells decreased in the FA group (P < 0.05). In the FA + PA group there were more immune Leydig cells reacting immune-positively than in the FA group (P < 0.05). Ultrastructurally, FA also caused disorganization and loss of mitochondrial cristae, and dilatation in endoplasmic reticulum in testes. Conclusion: The results suggest that PA has a protective effect on FA toxicity in testes.


Evaluation Of New Multiplex Pcr Primers For The Identification Ofplasmodium Species Found In Sabah, Malaysia, Cheronie Shely Stanis, Beng Kah Song, Tock Hing Chua, Yee Ling Lau, Jenarun Jelip Jan 2016

Evaluation Of New Multiplex Pcr Primers For The Identification Ofplasmodium Species Found In Sabah, Malaysia, Cheronie Shely Stanis, Beng Kah Song, Tock Hing Chua, Yee Ling Lau, Jenarun Jelip

Turkish Journal of Medical Sciences

Background/aim: Malaria is a major public health problem, especially in the Southeast Asia region, caused by 5 species of Plasmodium (P. falciparum, P. vivax, P. malariae, P. ovale, and P. knowlesi). The aim of this study was to compare parasite species identification methods using the new multiplex polymerase chain reaction (PCR) against nested PCR and microscopy. Materials and methods: Blood samples on filter papers were subject to conventional PCR methods using primers designed by us in multiplex PCR and previously designed primers of nested PCR. Both sets of results were compared with microscopic identification. Results: Of the 129 samples identified …


Clarifying Aspects Of Noninvasive Mechanical Ventilation In Acute Exacerbations Of Chronic Obstructive Pulmonary Disease, Annia Schreiber, Antonio Esquinas Jan 2016

Clarifying Aspects Of Noninvasive Mechanical Ventilation In Acute Exacerbations Of Chronic Obstructive Pulmonary Disease, Annia Schreiber, Antonio Esquinas

Turkish Journal of Medical Sciences

No abstract provided.


Behçet Syndrome: The Vascular Cluster, Hasan Yazici, Emi̇re Seyahi̇ Jan 2016

Behçet Syndrome: The Vascular Cluster, Hasan Yazici, Emi̇re Seyahi̇

Turkish Journal of Medical Sciences

No abstract provided.


Chronic Liver Diseases And Iron: A Concise Review With Emphasis On Hypotransferrinemia And Hypohepcidinemia, Naci̇ye Şemnur Büyükaşik, Yahya Büyükaşik Jan 2016

Chronic Liver Diseases And Iron: A Concise Review With Emphasis On Hypotransferrinemia And Hypohepcidinemia, Naci̇ye Şemnur Büyükaşik, Yahya Büyükaşik

Turkish Journal of Medical Sciences

No abstract provided.