Open Access. Powered by Scholars. Published by Universities.®

Medicine and Health Sciences Commons™

Open Access. Powered by Scholars. Published by Universities.®

2016

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 10891 - 10920 of 12713

Full-Text Articles in Medicine and Health Sciences

The Relationship Of Mean Platelet Volume With Retinopathy In Type 2 Diabetes Mellitus, Asli Araz Güngör, Gül Gürsoy, Fati̇h Güngör, Seyi̇t Murat Bayram, Eray Atalay Jan 2016

The Relationship Of Mean Platelet Volume With Retinopathy In Type 2 Diabetes Mellitus, Asli Araz Güngör, Gül Gürsoy, Fati̇h Güngör, Seyi̇t Murat Bayram, Eray Atalay

Turkish Journal of Medical Sciences

Background/aim: Patients with diabetes mellitus have an increased risk of developing micro- and macrovascular complications. Retinopathy is one of the most important complications of diabetes whose pathophysiological cause has not yet been determined. One candidate may be platelet volume. In this study we aimed to investigate the association between mean platelet volume and diabetic retinopathy. Materials and methods: Mean platelet volume levels were investigated in type 2 diabetic patients with and without retinopathy, and in healthy participants. After reclassifying our diabetics in terms of the presence or absence of hypertension and hyperlipidemia, we compared their mean platelet volumes. We then …

Go to article

Radiation Dose To Breasts From A Cardiac Computed Tomography Angiographyscanogram Can Be Reduced By Switching Tube Position, Mustafa Erdem Sağsöz, Rüstem Berhan Pi̇ri̇moğlu Jan 2016

Radiation Dose To Breasts From A Cardiac Computed Tomography Angiographyscanogram Can Be Reduced By Switching Tube Position, Mustafa Erdem Sağsöz, Rüstem Berhan Pi̇ri̇moğlu

Turkish Journal of Medical Sciences

Background/aim: In a computed tomography (CT) examination, scanogram images are used to determine the range of the area to be imaged before scanning. The importance of scanogram image exposure has increased since total examination radiation has decreased due to technological advancements. The purpose of this study was to determine and compare radiation doses delivered to patients while the tube was in anterior-posterior (AP) and posterior-anterior (PA) positions during a CT angiography scanogram. Materials and methods: The radiation doses absorbed by the breast tissue of 55 female patients who underwent cardiac dual-source computed tomography (DSCT) angiography were determined using thermoluminescent dosimeters …

Go to article

Anticyclic Citrullinated Peptide Antibody In Rheumatoid Arthritis:A Cross-Sectional Study In Iran, Irandokht Shenavar Masooleh, Asghar Hajiabbasi, Habib Zayeni, Atefeh Ghanbari, Violet Zaker Esteghamati, Banafsheh Ghavidel Parsa, Amir Hassankhani Jan 2016

Anticyclic Citrullinated Peptide Antibody In Rheumatoid Arthritis:A Cross-Sectional Study In Iran, Irandokht Shenavar Masooleh, Asghar Hajiabbasi, Habib Zayeni, Atefeh Ghanbari, Violet Zaker Esteghamati, Banafsheh Ghavidel Parsa, Amir Hassankhani

Turkish Journal of Medical Sciences

Background/aim: Studies have shown that anticyclic citrullinated peptide antibody (anti-CCP) titers can be useful in the diagnosis of rheumatoid arthritis (RA). We evaluate the association between anti-CCP antibody titers and the demographic, clinical, and laboratory characteristics of RA patients. Moreover, we explore whether there is any relation between joint destruction and demographic and clinical characteristics of RA patients. Materials and methods: One hundred and four RA patients with positive anti-CCP titers were compared to 104 RA patients with negative anti-CCP titers. The activity of RA was evaluated using the Disease Activity Score 28 (DAS28). Joint destruction was assessed in the …

Go to article

The Incidence Of Pressure Ulcer In Patients On Mechanical Ventilation Andeffects Of Selected Risk Factors On Pressure Ulcer Development*, Özgül Karayurt, Özay Akyol, Necmi̇ye Kiliçaslan, Nuray Akgün, Ümran Sargin, Meli̇ke Kondakçi, Hanim Eki̇nci̇, Nesli̇han Sari Jan 2016

The Incidence Of Pressure Ulcer In Patients On Mechanical Ventilation Andeffects Of Selected Risk Factors On Pressure Ulcer Development*, Özgül Karayurt, Özay Akyol, Necmi̇ye Kiliçaslan, Nuray Akgün, Ümran Sargin, Meli̇ke Kondakçi, Hanim Eki̇nci̇, Nesli̇han Sari

Turkish Journal of Medical Sciences

Background/aim: This study aimed to determine the incidence of pressure ulcers in patients on mechanical ventilation and selected risk factors likely to play a role in pressure ulcer development. Materials and methods: The study included 110 patients recruited from an anesthesia critical care unit of a university hospital. Data were collected with a demographic and clinical characteristics form. The form was composed of questions about demographic characteristics and clinical features including diagnosis, duration of mechanical ventilation, general well-being, oxygenation, perfusion, and skin condition. Results: The incidence of pressure ulcer was 15.5%. Duration of mechanical ventilation was longer and the body …

Go to article

An Investigation On The Prevalence And Efficiency Of Immunochromatographic Testing In Suspected Malarial Patients Of Rawalpindi And Islamabad, Pakistan, Saima Jabeen, Sobia Kanwal, Mazhar Qayyum, Umair Farrukh, Shahzad Abdul Hameed Jan 2016

An Investigation On The Prevalence And Efficiency Of Immunochromatographic Testing In Suspected Malarial Patients Of Rawalpindi And Islamabad, Pakistan, Saima Jabeen, Sobia Kanwal, Mazhar Qayyum, Umair Farrukh, Shahzad Abdul Hameed

Turkish Journal of Medical Sciences

Background/aim: The prevalences of Plasmodium falciparum and Plasmodium vivax are increasing rapidly in Pakistan, but recent data on the epidemiology of malaria are not properly reported with scarce diagnostic methods for quick diagnosis. This study was designed to determine the current prevalence and distribution of Plasmodium species in the vicinity of Rawalpindi and Islamabad and report on the validity of the immunochromatographic test (ICT) in diagnosing malarial infections. Materials and methods: A total of 1500 blood samples obtained from a local hospital were screened during the course of this study via microscopic examination and ICT. Results: It was seen that …

Go to article

The Association Of Vaspin Rs2236242 And Leptin Rs7799039 Polymorphism With Metabolic Syndrome In Egyptian Women, Amina Alnory, Hoda Gad, Gehan Hegazy, Olfat Shaker Jan 2016

The Association Of Vaspin Rs2236242 And Leptin Rs7799039 Polymorphism With Metabolic Syndrome In Egyptian Women, Amina Alnory, Hoda Gad, Gehan Hegazy, Olfat Shaker

Turkish Journal of Medical Sciences

Background/aim: Genetic predisposition is implicated in the etiology of metabolic syndrome. This study aimed to investigate the1397645907association of vaspin rs2236242 and leptin rs7799039 polymorphisms with their serum levels and with the risk of developing metabolic syndrome in Egyptian women.1397645907 Materials and methods: This case control study included 100 Egyptian women with metabolic syndrome and 100 without metabolic syndrome. The genotypes of vaspin rs2236242 and leptin rs7799039 were detected by a methodology based on PCR-RFLP. Serum vaspin and leptin levels were determined by ELISA. Results: The metabolic syndrome group was associated with higher serum vaspin and leptin levels when compared to …

Go to article

The Role Of Apelin In The Assessment Of Response To Chemotherapyand Prognosis In Stage 4 Nonsmall Cell Lung Cancer, Si̇nem Özsari, Gürsel Çok, Ali̇ Veral, Ti̇mur Köse Jan 2016

The Role Of Apelin In The Assessment Of Response To Chemotherapyand Prognosis In Stage 4 Nonsmall Cell Lung Cancer, Si̇nem Özsari, Gürsel Çok, Ali̇ Veral, Ti̇mur Köse

Turkish Journal of Medical Sciences

Background/aim: Prediction of response to chemotherapy and prognosis bears clinical significance in patients with lung cancer. The aim of the study was to examine the association between apelin expression in tumor tissues and overall survival, progression-free survival, chemoresistance, and treatment response in stage 4 nonsmall cell lung cancer (NSCLC) patients undergoing chemotherapy. Materials and methods: A total of 81 patients who received chemotherapy due to a biopsy-documented diagnosis of NSCLC between 2004 and 2011 were retrospectively studied. Bronchoscopic biopsy samples were examined immunohistochemically. Results: Of the overall study population (n = 81), the mean age was 59.0 ± 9.2 years; …

Go to article

Differentiated Thyroid Cancer In Patients With Prolactinoma, Abbas Ali̇ Tam, Cafer Kaya, Cevdet Aydin, Reyhan Ersoy, Beki̇r Çakir Jan 2016

Differentiated Thyroid Cancer In Patients With Prolactinoma, Abbas Ali̇ Tam, Cafer Kaya, Cevdet Aydin, Reyhan Ersoy, Beki̇r Çakir

Turkish Journal of Medical Sciences

Background/aim: Increasing evidence is available about the role of prolactin in the development of various cancers. The purpose of this study is to evaluate the frequency of thyroid cancer in patients with prolactinoma followed at a single site. Materials and methods: The medical records of 182 patients diagnosed with prolactinoma were reviewed retrospectively. Serum prolactin, antithyroglobulin, antithyroid peroxidase antibody, thyroid-stimulating hormone, free T4, and free T3 values and pituitary gland magnetic resonance imaging and thyroid ultrasound reports were evaluated. Results: Forty-five (39.5%) patients were found to have a thyroid nodule (13 solitary, 32 multiple). Ten patients were administered a thyroidectomy, …

Go to article

Cognitive Impairment One Year After Ischemic Stroke: Predictorsand Dynamics Of Significant Determinants, Margarita Lubomirova Alexandrova, Maya Penkova Danovska Jan 2016

Cognitive Impairment One Year After Ischemic Stroke: Predictorsand Dynamics Of Significant Determinants, Margarita Lubomirova Alexandrova, Maya Penkova Danovska

Turkish Journal of Medical Sciences

Background/aim: Evidence suggests that the risk for dementia increases after stroke. This study investigated the dynamics of the neurological and cognitive status of patients with no baseline dementia over a 1-year period after ischemic stroke. Materials and methods: We examined 47 ischemic stroke patients admitted within 48 h of ictus. Their neurological and cognitive statuses, blood biochemical parameters, and microalbuminuria levels were prospectively evaluated over a 1-year period post-stroke. Results: A more severe neurological deficit was found in the cognitively impaired patients (P = 0.003). The NIHSS score over a 1-year follow-up period improved only in patients with normal cognition …

Go to article

Cost Analysis And Evaluation Of Nosocomial Infections In Intensive Care Units, Uğur Kostakoğlu, Sedat Saylan, Mevlüt Karataş, Serap İskender, Fi̇rdevs Aksoy, Gürdal Yilmaz Jan 2016

Cost Analysis And Evaluation Of Nosocomial Infections In Intensive Care Units, Uğur Kostakoğlu, Sedat Saylan, Mevlüt Karataş, Serap İskender, Fi̇rdevs Aksoy, Gürdal Yilmaz

Turkish Journal of Medical Sciences

Background/aim: The purpose of this study was to evaluate nosocomial infections occurring in our hospital intensive care units (ICUs) and the risk factors for these, and to determine the effect of these infections on mortality and cost. Materials and methods: This retrospective study was performed via infection control committee surveillance data, ICU records, and information processing data between 1 January and 31 December 2013 at the Kanuni Education and Research Hospital. Results: A total of 309 nosocomial infections were observed in 205 out of 566 patients. The density of nosocomial infections was 25.4 in 1000 patient days. Hospitalization was prolonged, …

Go to article

Examination Of Factors Affecting Women?S Barrier Perception To Participate In Breast Cancer Screenings In A Region Affiliated With A Family Health Center In Turkey, Fatma Ersi̇n, Peri̇han Polat Jan 2016

Examination Of Factors Affecting Women?S Barrier Perception To Participate In Breast Cancer Screenings In A Region Affiliated With A Family Health Center In Turkey, Fatma Ersi̇n, Peri̇han Polat

Turkish Journal of Medical Sciences

Background/aim: This study was conducted in order to determine the factors related to women's barrier perception to participate in breast cancer screenings in a region affiliated with a family health center. Materials and methods: The study was a cross-sectional study. The sample group of the study consisted of 300 women. Descriptive statistics, t test, and Mann-Whitney U test were performed for the analysis of the data. Results: Breast self-examination (BSE) and mammography barrier perception mean score of those who were illiterate in terms of educational status, and BSE and mammography barrier perception mean score of those who were single in …

Go to article

Efficacy Of Mitomycin-C And Infliximab In Reducing Adhesionand Fibrosis Following Strabismus Surgery*, Emi̇n Serbülent Güçlü, Ayşe Ayça Sari, Erdem Di̇nç, Tuba Özcan Meti̇n, Banu Coşkun Yilmaz, Bahar Taşdelen Jan 2016

Efficacy Of Mitomycin-C And Infliximab In Reducing Adhesionand Fibrosis Following Strabismus Surgery*, Emi̇n Serbülent Güçlü, Ayşe Ayça Sari, Erdem Di̇nç, Tuba Özcan Meti̇n, Banu Coşkun Yilmaz, Bahar Taşdelen

Turkish Journal of Medical Sciences

Background/aim: The present study aimed to investigate the efficacy of mitomycin-C (MMC) and infliximab (INF) in reducing adhesion and fibrosis following strabismus surgery. Materials and methods: Forty eyes of 20 albino rabbits were separated into MMC and INF groups. Right and left eyes of rabbits were assigned to the drug and control groups, respectively. The superior rectus muscle was disinserted, the drug was administered to the surgical area for 5 min in the drug eyes (MMC 0.2 mg/mL or INF 5 mg/mL), and physiological saline was administered to the control eyes. Surgical areas were rinsed with 10 mL of physiological …

Go to article

The Efficacy Of Oral Ribavirin On Clinical And Laboratory Parameters Incrimean?Congo Hemorrhagic Fever: An Observational Study From Turkey*, Günay Ertem, Meli̇ha Çağla Sönmezer, Fati̇h Temoçi̇n, Çi̇ğdem Ataman Hati̇poğlu, Necla Tülek, Behi̇ç Oral Jan 2016

The Efficacy Of Oral Ribavirin On Clinical And Laboratory Parameters Incrimean?Congo Hemorrhagic Fever: An Observational Study From Turkey*, Günay Ertem, Meli̇ha Çağla Sönmezer, Fati̇h Temoçi̇n, Çi̇ğdem Ataman Hati̇poğlu, Necla Tülek, Behi̇ç Oral

Turkish Journal of Medical Sciences

Background/aim: In this observational study, the effects of oral ribavirin on clinical and laboratory parameters and blood products use in patients with Crimean-Congo hemorrhagic fever (CCHF) were evaluated. Materials and methods: CCHF patients (n = 100) who were hospitalized between 2007 and 2010 were included. Oral ribavirin was administered to 56 patients with symptom duration less than 5 days. Forty-four patients did not receive ribavirin (control group). The patients that received ribavirin in the first 3 days following the initiation of symptoms were designated as Group 1 (n = 29) and the others were designated as Group 2. Results: Ribavirin-treated …

Go to article

Serum Procalcitonin And C-Reactive Protein Kinetics As Indicators Of Treatmentoutcome In Hospitalized Patients With Community-Acquired Pneumonia, Mehmet Sezai̇ Taşbakan, Canan Gündüz, Abdullah Sayiner, Aykut Çi̇lli̇, Burcu Çelenk Karaboğa, Ayşin Şakar Coşkun, Feri̇de Durmaz Yaman, Oğuz Kilinç, Öznur Kiliç Soylar Jan 2016

Serum Procalcitonin And C-Reactive Protein Kinetics As Indicators Of Treatmentoutcome In Hospitalized Patients With Community-Acquired Pneumonia, Mehmet Sezai̇ Taşbakan, Canan Gündüz, Abdullah Sayiner, Aykut Çi̇lli̇, Burcu Çelenk Karaboğa, Ayşin Şakar Coşkun, Feri̇de Durmaz Yaman, Oğuz Kilinç, Öznur Kiliç Soylar

Turkish Journal of Medical Sciences

Background/aim: There has been growing interest in the use of serum procalcitonin (PCT) and C-reactive protein (CRP) in patients with community-acquired pneumonia (CAP). The aim of this study was to investigate whether an assessment of fever, leukocyte count, and serum CRP and PCT levels on admission and during follow-up (day 3) provides any information about the clinical outcome in hospitalized patients with CAP. Materials and methods: Patients with a diagnosis of CAP who were admitted to and followed at four university hospitals were evaluated retrospectively using the Turkish Thoracic Society Pneumonia Database. Results: A total of 103 hospitalized CAP patients …

Go to article

Lung Transplantation In Turkey: Lessons From Surgeons And Pulmonologists, Gül Dabak, Levent Dalar, Erdal Taşçi, Stephen Clark Jan 2016

Lung Transplantation In Turkey: Lessons From Surgeons And Pulmonologists, Gül Dabak, Levent Dalar, Erdal Taşçi, Stephen Clark

Turkish Journal of Medical Sciences

Background/aim: In order to actualize an efficient lung transplantation program, it is necessary to determine priorities and set up strategies. This study aimed to estimate the present situation in Turkey by determining the level of interest and knowledge of pulmonologists and thoracic surgeons regarding lung transplantation. Materials and methods: A questionnaire was prepared to establish the level of interest and knowledge of physicians on lung transplantation. It was sent to 2131 pulmonologists and thoracic surgeons, and 130 physicians completed the questionnaire. Results: Of the 130 physicians who responded, 42 were thoracic surgeons and 88 were pulmonologists. There was no significant …

Go to article

The Increasing Incidence Of Esophageal Squamous Cell Carcinoma In Women In Turkey, Ati̇la Eroğlu, Yener Aydin, Bayram Altuntaş, Betül Gündoğdu, Ömer Yilmaz Jan 2016

The Increasing Incidence Of Esophageal Squamous Cell Carcinoma In Women In Turkey, Ati̇la Eroğlu, Yener Aydin, Bayram Altuntaş, Betül Gündoğdu, Ömer Yilmaz

Turkish Journal of Medical Sciences

Background/aim: This study assessed the trend changes in the histological types of esophageal cancer in a 25-year period in eastern Turkey. Materials and methods: We searched all cases of esophageal cancer from 1990 to 2015 according to their histological diagnosis and sex, grouping the patients in 5-year time periods to evaluate time trends. Results: We identified 1462 cases of esophageal cancer. In terms of patient make-up, 742 were male and 720 were female. In general, 75.86% of the patients had squamous cell carcinoma (SCC), 19.56% of the patients had adenocarcinoma (ADC), and the remaining 4.58% patients were found to have …

Go to article

The Common Genetic Variants Of Toll-Like Receptor And Susceptibilityto Adenoid Hypertrophy: A Hospital-Based Cohort Study, Mehmet Ali̇ Babademez, Tali̇h Özdaş, Si̇bel Özdaş Jan 2016

The Common Genetic Variants Of Toll-Like Receptor And Susceptibilityto Adenoid Hypertrophy: A Hospital-Based Cohort Study, Mehmet Ali̇ Babademez, Tali̇h Özdaş, Si̇bel Özdaş

Turkish Journal of Medical Sciences

Background/aim: Adenoid hypertrophy (AH) is one of the most frequent pediatric disorders. The aim of this study was to investigate the effects of TLR2-R753Q, TLR4-T399I, and TLR4-D299G polymorphisms in children with AH. Materials and methods: The variants of the TLR gene were determined by restriction fragment length polymorphism (PCR-RFLP) analysis in 60 patients with AH and in 50 healthy children. Data were analyzed with SNPStats and multifactor dimensionality reduction (MDR) software. Results: We found that the presence of the G allele, the AG+GG and AG genotypes at TLR4-D299G, and the GGT haplotype were associated with AH in children (P = …

Go to article

Neurological Outcome After Cardiac Arrest: A Prospective Study Of The Predictive Ability Of Prognostic Biomarkers Neuron-Specific Enolase, Glial Fibrillary Acidic Protein, S-100b, And Procalcitonin, Gülay Ok, Demet Aydin, Koray Erbüyün, Canan Gürsoy, Fatma Taneli̇, Sema Bi̇lge, Gönül Di̇nç Horasan Jan 2016

Neurological Outcome After Cardiac Arrest: A Prospective Study Of The Predictive Ability Of Prognostic Biomarkers Neuron-Specific Enolase, Glial Fibrillary Acidic Protein, S-100b, And Procalcitonin, Gülay Ok, Demet Aydin, Koray Erbüyün, Canan Gürsoy, Fatma Taneli̇, Sema Bi̇lge, Gönül Di̇nç Horasan

Turkish Journal of Medical Sciences

Background/aim: Factors affecting neurological outcome and the usefulness of neuron-specific enolase (NSE), S-100B, glial fibrillary acidic protein (GFAP), and procalcitonin (PCT) in predicting neurological outcomes were assessed in patients who survived at least 24 h after cardiopulmonary resuscitation (CPR). Materials and methods: Thirty successfully resuscitated cardiac arrest patients were included in this prospective clinical study. The initial cardiac arrest rhythm, duration of CPR, return of spontaneous circulation time, administered doses of adrenaline, base excess, blood sugar, and hemodynamic parameters were recorded. Patients with Glasgow Outcome Scale (GOS) scores of 1-3 were defined as Group I and patients with GOS scores …

Go to article

Factors Affecting Treatment Success In Community-Acquired Pneumonia, Canan Gündüz, Mehmet Sezai̇ Taşbakan, Abdullah Sayiner, Aykut Çi̇lli̇, Oğuz Kilinç, Ayşin Şakar Coşkun Jan 2016

Factors Affecting Treatment Success In Community-Acquired Pneumonia, Canan Gündüz, Mehmet Sezai̇ Taşbakan, Abdullah Sayiner, Aykut Çi̇lli̇, Oğuz Kilinç, Ayşin Şakar Coşkun

Turkish Journal of Medical Sciences

Background/aim: Treatment failure in hospitalized patients with community-acquired pneumonia is a major cause of mortality. The aim of this study was to evaluate the factors affecting treatment success in community-acquired pneumonia. Materials and methods: A total of 537 patients (mean age: 66.1 ± 15.8 years, 365 males) registered to the Turkish Thoracic Society Pneumonia Database were analyzed. Of these, clinical improvement or cure, defined as treatment success, was achieved in 477, whereas 60 patients had treatment failure and/or died. Results: Lower numbers of neutrophils (5989.9 ± 6237.3 vs. 8495.6 ± 7279.5/mm3), higher blood urea levels (66.1 ± 42.1 vs. 51.2 …

Go to article

Evaluation Of Cutaneous Anthrax Cases During An Outbreak In The East Region Of Turkey, Esra Kural Ünüvar, Deni̇z Bahar Akgün Karapinar, Nazli Di̇zen Namdar Jan 2016

Evaluation Of Cutaneous Anthrax Cases During An Outbreak In The East Region Of Turkey, Esra Kural Ünüvar, Deni̇z Bahar Akgün Karapinar, Nazli Di̇zen Namdar

Turkish Journal of Medical Sciences

Background/aim: Anthrax is a zoonotic infection caused by Bacillus anthracis. We aimed to retrospectively evaluate cutaneous anthrax cases that occurred during an outbreak in eastern Turkey (Hakkari-Yüksekova), where people mostly earn their living from animal husbandry. Materials and methods: Forty-six cutaneous anthrax patients that were admitted to the hospital during a very short duration of 3 months (June-August 2011) were evaluated. Results: Out of 46 patients, 27 (52%) were women and 19 (48%) were men. The mean age was 37 ± 13 years. The distribution of occupations was 1 butcher, 1 cook, 5 farmers, 27 housewives, 11 shepherds, and 1 …

Go to article

Health-Related Quality Of Life Of Pediatric Renal Transplant Recipientsand Their Parents: The Role Of Associated Factors And Clinical Counseling, Bahar Büyükkaragöz, Necla Buyan, Nahi̇de Doğrucan, Bülent Çeli̇k Jan 2016

Health-Related Quality Of Life Of Pediatric Renal Transplant Recipientsand Their Parents: The Role Of Associated Factors And Clinical Counseling, Bahar Büyükkaragöz, Necla Buyan, Nahi̇de Doğrucan, Bülent Çeli̇k

Turkish Journal of Medical Sciences

Background/aim: This study evaluates the health-related quality of life (HRQoL) of pediatric renal transplant recipients and their parents and investigates the effects of clinical, socioeconomic, and psychological factors as well as continuous counseling on the HRQoL. Materials and methods: Patients aged 8-17 years (mean: 14.9 ± 2.9) were enrolled. Clinical and demographic data were noted. The Beck Depression Inventory (BDI), Rosenberg Self-Esteem Scale (RSES), and Turkish version of the Kinder Lebensqualität Fragebogen (KINDL) questionnaire for children and the BDI, RSES, parent-proxy version of KINDL, and Short-Form 36 (SF-36) for parents were applied (step 1). Following a 1-year counseling program, the …

Go to article

The Frequency Of Buccopalpebral Reflex In Parkinson Disease, Hülya Eser, Yasemi̇n Ünal, Gülni̇hal Kutlu, Ruhsen Öcal, Levent Ertuğrul İnan Jan 2016

The Frequency Of Buccopalpebral Reflex In Parkinson Disease, Hülya Eser, Yasemi̇n Ünal, Gülni̇hal Kutlu, Ruhsen Öcal, Levent Ertuğrul İnan

Turkish Journal of Medical Sciences

Background/aim: This study aimed to define the frequency of a primitive reflex, the buccopalpebral reflex (BPR), and its association with the clinical situation in patients with Parkinson disease. Materials and methods: Between May 2010 and May 2011, 222 patients, 115 with Parkinson disease and 107 patients without any sign of neurodegenerative disease, were included in the study. All included patients were examined for BPR and snout reflex and were also evaluated with the Mini Mental State Examination. All patients with Parkinson disease were classified with the Unified Parkinson's Disease Rating Scale (UPDRS) and the Hoehn and Yahr Score to determine …

Go to article

The Effect Of Cotinine Concentrations In Seminal Plasma And Follicular Fluid On The Pregnancy Outcomes Of Couples Undergoing Assisted Reproductive Techniques, Füsun Terzi̇oğlu, Bensu Karahali̇l, Çi̇ğdem Yücel, Ruki̇ye Türk Jan 2016

The Effect Of Cotinine Concentrations In Seminal Plasma And Follicular Fluid On The Pregnancy Outcomes Of Couples Undergoing Assisted Reproductive Techniques, Füsun Terzi̇oğlu, Bensu Karahali̇l, Çi̇ğdem Yücel, Ruki̇ye Türk

Turkish Journal of Medical Sciences

Background/aim: This study determined the effects of cotinine concentrations in follicular fluid (FF) and seminal plasma (SP) on the pregnancy outcome of couples using assisted reproductive techniques (ARTs). Materials and methods: This study was conducted as a case-control study. A total of 217 couples were included in the study. Among these couples, there were nonsmokers (66 women and 40 men), passive smokers (106 women and 54 men), and active smokers (45 women and 123 men). Demographic and smoking data were collected by questionnaire at the onset of treatment. FF and SP samples were obtained from the couples on the day …

Go to article

Genotypic Analysis Of Escherichia Coli Strains That Cause Urosepsis In The Aegean Region, Betül Gi̇ray, Füsun Bahri̇ye Uçar, Sabi̇re Şöhret Aydemi̇r Jan 2016

Genotypic Analysis Of Escherichia Coli Strains That Cause Urosepsis In The Aegean Region, Betül Gi̇ray, Füsun Bahri̇ye Uçar, Sabi̇re Şöhret Aydemi̇r

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to characterize strains genotypically, to determine their phylogenetic relationships, to investigate the presence of the papG gene, and to compare their antibiotic susceptibility test results. Materials and methods: Seventy pathogenic E. coli strains were isolated from both urine and blood cultures of patients with the preliminary diagnosis of urosepsis who were referred to the Ege University Faculty of Medicine, Bacteriology Laboratory of Medical Microbiology Department in İzmir. All of these strains were examined for the papG gene and phylogenetic groups with the multiplex polymerase chain reaction technique. Pulsed-field gel electrophoresis and multilocus sequence …

Go to article

The Effect Of Pneumoperitoneum On Intravascular Fibrinolytic Activity In Rats, Kürşat Di̇kmen, Asi̇ye Uğraş Di̇kmen, Hasan Bostanci, Ahmet Karamercan, Abdullah Münci̇ Yağci, Murat Akin, Bülent Aytaç Jan 2016

The Effect Of Pneumoperitoneum On Intravascular Fibrinolytic Activity In Rats, Kürşat Di̇kmen, Asi̇ye Uğraş Di̇kmen, Hasan Bostanci, Ahmet Karamercan, Abdullah Münci̇ Yağci, Murat Akin, Bülent Aytaç

Turkish Journal of Medical Sciences

Background/aim: Venous stasis during pneumoperitoneum in laparoscopic surgery is closely related to fibrin synthesis and deposition. The etiologic factors underlying fibrinolysis or hypercoagulability are not clearly defined. This study aimed to determine the effects of pneumoperitoneum time and pressure on coagulation cascade and the fibrinolytic pathway. Materials and methods: After the pneumoperitoneum model was established in rats, PAI-1, tPA, TAFI, D-dimer, and fibrinogen activities were evaluated in different time periods under different pressures in groups including 6 rats. Group 1 did not undergo any procedure. Group 2 received 8 mmHg of pressure for 30 min, Group III 8 mmHg for …

Go to article

The Protective Effects Of Hydrogen On Ho-1 Expression In The Brainafter Focal Cerebral Ischemia Reperfusion In Rats, Xifeng Wang, Lianshuang Zhang, Wei Zhao, Tongshen Liu Jan 2016

The Protective Effects Of Hydrogen On Ho-1 Expression In The Brainafter Focal Cerebral Ischemia Reperfusion In Rats, Xifeng Wang, Lianshuang Zhang, Wei Zhao, Tongshen Liu

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to investigate whether a hydrogen administration can produce neuroprotective effects after brain ischemia reperfusion in rats. Materials and methods: A brain ischemia reperfusion injury was induced by a 2-h left middle cerebral artery occlusion (MCAO) using an intraluminal filament, followed by 46 h of reperfusion. A hydrogen-rich saline (1 mL/kg body weight i.p.) was administered at the beginning of reperfusion. Saline (1 mL/kg)-treated animals were used as the control. Sham-operated animals were also used. Subsequently, 48 h after the MCAO, histological alternations, heme oxygenase-1 (HO-1) expression, and levels of malondialdehyde (MDA) and superoxide …

Go to article

Effect Of Methylprednisolone Injection On Interleukin-4 And Interferon-Gamma Expression Following Hepatitis B Vaccination In Mice, Peter Ughachukwu, Paul Okonkwo, Prince Unekwe, John Ogamba Jan 2016

Effect Of Methylprednisolone Injection On Interleukin-4 And Interferon-Gamma Expression Following Hepatitis B Vaccination In Mice, Peter Ughachukwu, Paul Okonkwo, Prince Unekwe, John Ogamba

Turkish Journal of Medical Sciences

Background/aim: The prevalence of hepatitis B infection is high worldwide with liver cirrhosis and hepatocellular carcinoma as important complications. Immunosuppression, especially from corticosteroids, is often cited as a cause of poor immune response and there is documented evidence of irrational administration of glucocorticoids to children and adults. Decreased expression of interleukin-4 and interferon-gamma is an indication of poor humoral and cellular immune responses, respectively. Therefore, we decided to find out if methylprednisolone injection decreases interleukin-4 and interferon-gamma expression following hepatitis B vaccination in mice. Materials and methods: Mice were randomly divided into 2 groups. Daily intramuscular injections of methylprednisolone (15 …

Go to article

Adulthood Behavioral And Neurodevelopmental Effects Of Being Raised Byan Ambivalent Mother In Rats: What Does Not Kill You Makes You Stronger, Refi̇a Aslihan Dönmez, Selçuk Candansayar, Okşan Deri̇nöz, Özlem Gülbahar, Hayrunni̇sa Bolay Jan 2016

Adulthood Behavioral And Neurodevelopmental Effects Of Being Raised Byan Ambivalent Mother In Rats: What Does Not Kill You Makes You Stronger, Refi̇a Aslihan Dönmez, Selçuk Candansayar, Okşan Deri̇nöz, Özlem Gülbahar, Hayrunni̇sa Bolay

Turkish Journal of Medical Sciences

Background/aim: This study aimed to investigate the effects of early adverse life events and being raised by an ambivalent mother on rats. Materials and methods: The rats were separated into four groups: 1) the control group (n = 12), which was raised under standard care; 2) the early handling (EH) group, which was raised using an EH model (n = 16); 3) the early deprivation (ED) group, which was raised using an ED model (n = 13), and 4) the ambivalent mother (AM) group, which spent 3 h/day with a "fake mother" (n = 17). When they became adults, their …

Go to article

Effect Of Resveratrol On Resistin And Apelin Gene Expressions In Adipose Tissue Of Diabetic Rats, Sadegh Zarei, Massoud Saidijam, Jamshid Karimi, Reza Yadegarazari, Azam Rezaei Farimani, Solmazsaadat Hosseini-Zijood, Mohammad Taghi Goodarzi Jan 2016

Effect Of Resveratrol On Resistin And Apelin Gene Expressions In Adipose Tissue Of Diabetic Rats, Sadegh Zarei, Massoud Saidijam, Jamshid Karimi, Reza Yadegarazari, Azam Rezaei Farimani, Solmazsaadat Hosseini-Zijood, Mohammad Taghi Goodarzi

Turkish Journal of Medical Sciences

Background/aim: Adipose tissue plays a major role in glucose homeostasis. Dietary antioxidants such as resveratrol (RSV) may offer some protection against the early stage of diabetes mellitus and the development of complications. The present study investigated the effects of RSV on biochemical parameters and resistin and apelin gene expressions in adipose tissue of rats with type 2 diabetes. Materials and methods: Diabetes was induced using a single dose of streptozotocin + nicotinamide. Three groups of diabetic rats were treated with different doses of RSV (1, 5, and 10 mg/kg body weight per day). Oxidative status, serum biochemical parameters, insulin, and …

Go to article

Therapeutic Effects Of Intralipid And Medialipid Emulsionsin A Rat Model Of Verapamil Toxicity, Fatma Akgün Şahi̇n, Sidika Hülya Çelebi̇, İrfan Güngör, Demet Coskun, Eli̇f Ergüven Kaya Jan 2016

Therapeutic Effects Of Intralipid And Medialipid Emulsionsin A Rat Model Of Verapamil Toxicity, Fatma Akgün Şahi̇n, Sidika Hülya Çelebi̇, İrfan Güngör, Demet Coskun, Eli̇f Ergüven Kaya

Turkish Journal of Medical Sciences

Background/aim: Lipid emulsions are promising as a potential new therapy for severe verapamil overdose. Our purpose is to draw attention to the choice of solution by investigating the efficacy of intralipid 20% or medialipid 20% in verapamil overdose. Materials and methods: Eighteen adult Sprague Dawley rats were randomly divided into three groups: control (saline; Group C), intralipid 20% (Group I), and medialipid 20% (Group M). Rats were anesthetized with ketamine. Blood gas analysis, baseline heart rate (HRb), and mean arterial pressure (MAPb) were evaluated. Verapamil at 2.5 mg kg-1 min-1 was infused until the HRb and MAPb decreased by 50% …

Go to article

First Prev Next Last