Open Access. Powered by Scholars. Published by Universities.®

Medicine and Health Sciences Commons™

Open Access. Powered by Scholars. Published by Universities.®

2016

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 10441 - 10470 of 12713

Full-Text Articles in Medicine and Health Sciences

Chronic Cough: Clinical Characteristics And Etiologies Of 510 Cases, Guiyuan Jiang, Xinying Huang, Tianlin Li, Dongping Xu Jan 2016

Chronic Cough: Clinical Characteristics And Etiologies Of 510 Cases, Guiyuan Jiang, Xinying Huang, Tianlin Li, Dongping Xu

Turkish Journal of Medical Sciences

Background/aim: To investigate the clinical features and underlying etiologies of chronic cough (CC). Materials and methods: Five hundred and ten CC patients were enrolled. The phases, characteristics and associated clinical manifestations of CC among the gastroesophageal reflux cough (GERC), cough-variant asthma (CVA), and upper airway cough syndrome (UACS) groups were compared, and the diagnostic values of each group were evaluated by multiple regression analysis. Results: In the 510 patients, 404 had CC with single etiology-GERC (n = 175), CVA (n = 134), and UACS (n = 95). The characteristic features of GERC included gastric acid backflow symptoms such as sour-tasting …

Go to article

Pityriasis Rosea: A Natural History Of Pediatric Cases In Thecentral Anatolia Region Of Turkey, Emi̇ne Çölgeçen, Çi̇ğdem Kader, Yilmaz Ulaş, Pinar Öztürk, Öznur Küçük, Mehmet Balci Jan 2016

Pityriasis Rosea: A Natural History Of Pediatric Cases In Thecentral Anatolia Region Of Turkey, Emi̇ne Çölgeçen, Çi̇ğdem Kader, Yilmaz Ulaş, Pinar Öztürk, Öznur Küçük, Mehmet Balci

Turkish Journal of Medical Sciences

Background/aim: This study aimed to evaluate the demographic, clinical, and epidemiological features of pityriasis rosea (PR) in a cohort of 46 children in Yozgat, a city in the Central Anatolia Region of Turkey. Materials and methods: Forty-six children with PR were monitored at regular intervals (1, 2, 4, and 12 weeks) for 3 months from the time of diagnosis. A complete evaluation of the patient was performed at each visit. Results: The average age of patients at time of diagnosis was 12 ± 3.9 years. Cases were most common in the winter (rainy, snowy months; n = 14, 31%). Fifteen …

Go to article

Sleep Quality In Opioid-Naive And Opioid-Dependent Patientson Methadone Maintenance Therapy In Malaysia, Zalina Zahari, Muslih Abdulkarim Ibrahim, Soo Choon Tan, Nasir Mohamad, Rusli Ismail Jan 2016

Sleep Quality In Opioid-Naive And Opioid-Dependent Patientson Methadone Maintenance Therapy In Malaysia, Zalina Zahari, Muslih Abdulkarim Ibrahim, Soo Choon Tan, Nasir Mohamad, Rusli Ismail

Turkish Journal of Medical Sciences

Background/aim: Sleep disturbances may contribute to poor treatment outcomes in opioid-dependent patients. The extent to which the sleep profiles of opioid-dependent patients differ from those of the general Malaysian population is not documented. This study compared opioid-naive subjects and opioid-dependent patients on methadone maintenance therapy (MMT) in terms of their sleep quality. Materials and methods: Participants comprised Malay male opioid-naive subjects (n = 159) and opioid-dependent patients (n = 160) from MMT clinics in Kelantan, Malaysia, between March and October 2013. Sleep quality was evaluated using the translated and validated Malay version of the Pittsburgh Sleep Quality Index (PSQI). Results: …

Go to article

Does Cpap Treatment Affect The Voice?, Güleser Saylam, Mustafa Şahi̇n, Di̇lek Demi̇ral, Ömer Bayir, Meli̇ke Bağnu Yüceege, Emel Çadalli Tatar, Mehmet Hakan Korkmaz Jan 2016

Does Cpap Treatment Affect The Voice?, Güleser Saylam, Mustafa Şahi̇n, Di̇lek Demi̇ral, Ömer Bayir, Meli̇ke Bağnu Yüceege, Emel Çadalli Tatar, Mehmet Hakan Korkmaz

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to investigate alterations in voice parameters among patients using continuous positive airway pressure (CPAP) for the treatment of obstructive sleep apnea syndrome. Materials and methods: Patients with an indication for CPAP treatment without any voice problems and with normal laryngeal findings were included and voice parameters were evaluated before and 1 and 6 months after CPAP. Videolaryngostroboscopic findings, a self-rated scale (Voice Handicap Index-10, VHI-10), perceptual voice quality assessment (GRBAS: grade, roughness, breathiness, asthenia, strain), and acoustic parameters were compared. Results: Data from 70 subjects (48 men and 22 women) with a mean …

Go to article

Acute Exudative Tonsillitis In Adults: The Use Of The Centor Scoreand Some Laboratory Tests, Yavuz Furuncuoğlu, Fi̇li̇z Sağlam, Ahmet Kutluhan Jan 2016

Acute Exudative Tonsillitis In Adults: The Use Of The Centor Scoreand Some Laboratory Tests, Yavuz Furuncuoğlu, Fi̇li̇z Sağlam, Ahmet Kutluhan

Turkish Journal of Medical Sciences

Background/aim: The aim of our study was to determine the usefulness of the Centor score and some basic laboratory tests (complete blood count and C-reactive protein) for the differential diagnosis of exudative tonsillitis due to Group A β-hemolytic streptococcus (GABHS) or due to non-GABHS agents. Materials and methods: The data of clinical and laboratory characteristics of the patients diagnosed with exudative tonsillitis were collected and statistically compared between those having positive GABHS throat culture result and those who were negative for any bacterial agent. Results: Totally 899 adult patients were included in our study; 56 (6.2%) of them were positive …

Go to article

Treatment Efficacy And Superinfection Rates In Complicated Urinarytract Infections Treated With Ertapenem Or Piperacillin Tazobactam, Murat Di̇zbay, Hasan Selçuk Özger, Ömer Karaşahi̇n, Emi̇ne Füsun Karaşahi̇n Jan 2016

Treatment Efficacy And Superinfection Rates In Complicated Urinarytract Infections Treated With Ertapenem Or Piperacillin Tazobactam, Murat Di̇zbay, Hasan Selçuk Özger, Ömer Karaşahi̇n, Emi̇ne Füsun Karaşahi̇n

Turkish Journal of Medical Sciences

Background/aim: In this retrospective study, the efficacy of ertapenem and piperacillin tazobactam was compared in the treatment of complicated urinary tract infections (cUTIs). Treatment responses were also evaluated for both antibiotics. Materials and methods: A total of 230 patients were enrolled in the study. Of these, 170 received ertapenem and 60 received piperacillin-tazobactam. Results: In both groups, urine cultures after 48 h were negative for the initial uropathogen. The frequency of superinfection was 29.4% in the ertapenem group and 8.3% in the piperacillin-tazobactam group over the duration of treatment (P < 0.05). Urinary catheterization increased the superinfection risk 2.88-fold in the ertapenem group and diabetes mellitus increased the risk 8.50-fold in the piperacillin-tazobactam group (CI: 1.44-5.76 and 1.16-62.09, respectively, P < 0.05). The main pathogen isolated from superinfection in the ertapenem group after 48 h was Enterococcus spp. (71.4%). Conclusion: Both ertapenem and piperacillin-tazobactam were effective in the treatment of cUTIs caused by ESBL-producing microorganisms. A high frequency of superinfection in the ertapenem group was the result of Enterococcus and Pseudomonas spp., against which ertapenem is not active. In the presence of urinary catheterization, diabetes mellitus, and urological intervention, patients should be closely monitored for the development of a superinfection, especially patients receiving ertapenem.

Go to article

Plasma Levels Of Serotonin, Gastrointestinal Symptoms,And Sleep Problems In Children With Autism, Sorayya Khkheirouri, Parinaz Kalejahi, Seyyed Gholamreza Noorazar Jan 2016

Plasma Levels Of Serotonin, Gastrointestinal Symptoms,And Sleep Problems In Children With Autism, Sorayya Khkheirouri, Parinaz Kalejahi, Seyyed Gholamreza Noorazar

Turkish Journal of Medical Sciences

Background/aim: Autism is a neurodevelopmental disorder identified with higher frequency of serotonin abnormalities and gastrointestinal (GI) and sleep problems. This study aimed to evaluate the plasma levels of serotonin, GI symptoms, and sleep problems, and their relationship with autism severity in children with autism. Materials and methods: Thirty-five children with autism and 31 healthy subjects were studied. GI problems, sleep disorders, and severity of disorder were assessed. Plasma serotonin was determined using ELISA. Results: There was no significant association between GI problems and autism severity, but a significant positive correlation was seen between different indicators of sleep disorder and severity …

Go to article

Biliary Stenting In Difficult Common Bile Duct Stones: A Single Tertiary Center Experience, Mahmut Yüksel, Selçuk Di̇şi̇beyaz, Mustafa Kaplan, Erkan Parlak, Hakan Yildiz, İhsan Ateş, Ertuğrul Kayaçeti̇n Jan 2016

Biliary Stenting In Difficult Common Bile Duct Stones: A Single Tertiary Center Experience, Mahmut Yüksel, Selçuk Di̇şi̇beyaz, Mustafa Kaplan, Erkan Parlak, Hakan Yildiz, İhsan Ateş, Ertuğrul Kayaçeti̇n

Turkish Journal of Medical Sciences

Background/aim: We aimed to examine the effect of plastic biliary stenting in the treatment of common bile duct (CBD) stones. Materials and methods: The data of 13,034 patients in our unit who had endoscopic retrograde cholangiopancreatography (ERCP) between 2008 and 2015 were scanned retrospectively. Results: A biliary stent was placed in 61 of 74 patients. While the plastic biliary stent was placed in patients, the mean stone size after the 1st ERCP was 20 mm and the bile duct size was 13 mm. At the time of the 2nd ERCP conducted approximately 73.9 days later, the mean stone size was …

Go to article

Segmental Epidural Anesthesia For Percutaneous Kyphoplasty:Comparison With General Anesthesia, Alparslan Apan, Özgün Cuvaş Apan, Emi̇ne Arzu Köse Jan 2016

Segmental Epidural Anesthesia For Percutaneous Kyphoplasty:Comparison With General Anesthesia, Alparslan Apan, Özgün Cuvaş Apan, Emi̇ne Arzu Köse

Turkish Journal of Medical Sciences

Background/aim: This is a feasibility study evaluating whether segmental epidural anesthesia is an alternative anesthetic approach to general anesthesia for percutaneous kyphoplasty. Materials and methods: After ethics committee approval was obtained, 52 ASA class I-III patients scheduled for elective, single-level percutaneous kyphoplasty were recruited. The patients were divided into two equal groups. In Group E (Group Epidural) segmental epidural anesthesia was performed using the loss of resistance technique with saline. In Group G (Group Control) general anesthesia was performed. Hemodynamic parameters, intraoperative and postoperative analgesic requirements, visual analogue scale (VAS) scores, length of stay in the postanesthesia care unit (PACU), …

Go to article

Surgical Management Of Large-Cell Neuroendocrinelung Carcinoma: An Analysis Of 25 Cases, Funda İncekara, Koray Aydoğdu, Ebru Sayilir, Seli̇m Şaki̇r Erkmen Gülhan, Funda Demi̇rağ, Sadi̇ Kaya, Göktürk Findik Jan 2016

Surgical Management Of Large-Cell Neuroendocrinelung Carcinoma: An Analysis Of 25 Cases, Funda İncekara, Koray Aydoğdu, Ebru Sayilir, Seli̇m Şaki̇r Erkmen Gülhan, Funda Demi̇rağ, Sadi̇ Kaya, Göktürk Findik

Turkish Journal of Medical Sciences

Background/aim: Large-cell neuroendocrine carcinoma (LCNEC) of the lung is a relatively uncommon and aggressive subset of pulmonary neuroendocrine tumors, which include typical and atypical carcinoid, and small-cell lung cancer. LCNEC of the lung accounts for no more than 1% of all lung cancers. LCNECs show features of high-grade neuroendocrine tumors and patients with LCNEC have a very poor prognosis. Materials and methods: Twenty-five patients (22 males and 3 females; mean years 60.7; range 48 to 77 years) who underwent pulmonary resection for large-cell neuroendocrine carcinoma between January 2004 and December 2014 were investigated retrospectively. Results: Type of surgery, pathologic TNM …

Go to article

Comparison Of The Distinctive Pathological Features Of And P16 And C-Kitexpression Levels In Benign And Malignant Endometrial Polyps, Nermi̇n Koç, Selçuk Ayas, Lütfi̇ye Uygur, Nurver Özel Özbay Jan 2016

Comparison Of The Distinctive Pathological Features Of And P16 And C-Kitexpression Levels In Benign And Malignant Endometrial Polyps, Nermi̇n Koç, Selçuk Ayas, Lütfi̇ye Uygur, Nurver Özel Özbay

Turkish Journal of Medical Sciences

Background/aim: Histopathological examination is crucial for the effective management of endometrial polyps. Immunohistochemical markers such as p16 and c-Kit may facilitate the differential diagnoses of benign and malignant polyps. The aim of the present study was to explore the expression levels of c-Kit (CD117) and p16 in endometrial polyps of postmenopausal women. Materials and methods: Twenty-five hysterectomy specimens with malignant endometrial polyps and hysterectomy or polypectomy specimens featuring 55 benign polyps were studied. The polyps were immunohistochemically stained for p16 and c-Kit, and differences in the expression levels of these proteins in the glandular and stromal components of benign polyps …

Go to article

Comparison Of Wire-Guided Localization And Radio-Guided Occult Lesionlocalization In Preoperative Localization Of Nonpalpable Breast Lesions, Nazim Bariş Kanat, Murat Tuncel, Tamer Aksoy, Ayşegül Firat, Fi̇gen Demi̇rkazik, Demi̇rali̇ Onat, Meltem Çağlar Tuncali, Bi̇ray Emi̇ne Caner Jan 2016

Comparison Of Wire-Guided Localization And Radio-Guided Occult Lesionlocalization In Preoperative Localization Of Nonpalpable Breast Lesions, Nazim Bariş Kanat, Murat Tuncel, Tamer Aksoy, Ayşegül Firat, Fi̇gen Demi̇rkazik, Demi̇rali̇ Onat, Meltem Çağlar Tuncali, Bi̇ray Emi̇ne Caner

Turkish Journal of Medical Sciences

Background/aim: Breast lesions that are not palpable on physical examination but considered suspicious for malignancy on mammography or ultrasonography should be marked before surgery. Wire-guided localization (WGL) is the most frequently used method for preoperative marking of nonpalpable breast lesions (NPBLs). An alternative is marking by a radioactive agent (radio-guided occult lesion localization; ROLL). The present study aimed to compare WGL and ROLL for preoperative marking. Materials and methods: The study included 25 patients marked by ROLL and 11 patients marked by WGL. The groups were compared in terms of patient and lesion characteristics, method-related characteristics, hospital stay duration, complications, …

Go to article

The Factors Affecting Survival In Patients With Bronchiectasis, Fatma Çi̇ftci̇, Eli̇f Şen, Sevgi̇ Behi̇ye Saryal, Zeynep Pinar Önen, Banu Gülbay, Öznur Yildiz, Turan Acican, Gülseren Karabiyikoğlu Jan 2016

The Factors Affecting Survival In Patients With Bronchiectasis, Fatma Çi̇ftci̇, Eli̇f Şen, Sevgi̇ Behi̇ye Saryal, Zeynep Pinar Önen, Banu Gülbay, Öznur Yildiz, Turan Acican, Gülseren Karabiyikoğlu

Turkish Journal of Medical Sciences

Background/aim: There is limited information about the rate and modifiers of mortality in noncystic fibrosis bronchiectasis. Materials and methods: This study enrolled a total of 56 bronchiectasis patients. Patients' body mass index, smoking habit, previous therapies, comorbid disorders, history of vaccination, bronchiectasis type and radiological extent, arterial blood gas analysis, respiratory function tests, and laboratory results were recorded. Results: After a follow-up of 65.38 ± 18.62 months the overall mortality rate was 35.7%. The mean survival duration was 46.42 ± 8.25 months. Advanced age significantly increased mortality (HR: 2.031; CI: 0.991?4.072, P = 0.035). A significant correlation was found between …

Go to article

Do Anxiety And Depression Statuses Differ In Differentpolycystic Ovary Syndrome Phenotypes?, Derya Akdağ Ci̇ri̇k, Berna Di̇lbaz, Sezi̇n Ertürk Aksakal, Zeynep Kotan, Runa Özelçi̇, Funda Akpinar, Leyla Mollamahmutoğlu Jan 2016

Do Anxiety And Depression Statuses Differ In Differentpolycystic Ovary Syndrome Phenotypes?, Derya Akdağ Ci̇ri̇k, Berna Di̇lbaz, Sezi̇n Ertürk Aksakal, Zeynep Kotan, Runa Özelçi̇, Funda Akpinar, Leyla Mollamahmutoğlu

Turkish Journal of Medical Sciences

Background/aim: To evaluate psychological parameters and health quality profiles in women with reproductive polycystic ovary syndrome (PCOS) phenotypes and age matched controls. Materials and methods: The study groups included 101 women with PCOS (54 with the National Institutes of Health [NIH] phenotype and 47 with the non-NIH phenotype) and 49 healthy female controls. The participants completed anxiety and depression scales and four quality of life domains. Results: We identified the women with PCOS as having a 3.39 times increased risk for depression (subscale ≥ 7) and a 3.64 times increased risk for anxiety (subscale ≥ 10) compared to the controls. …

Go to article

New Immunohistochemical Markers In The Differential Diagnosisof Nonsmall Cell Lung Carcinoma, Ferda Bi̇r, Duygu Çeli̇ker, Bi̇nnaz Fatma Evyapan, Arzu Yaren, Tamer Edi̇rne Jan 2016

New Immunohistochemical Markers In The Differential Diagnosisof Nonsmall Cell Lung Carcinoma, Ferda Bi̇r, Duygu Çeli̇ker, Bi̇nnaz Fatma Evyapan, Arzu Yaren, Tamer Edi̇rne

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to investigate Napsin-A, NTRK-1, NTRK-2, Desmoglein-3, and Desmocollin-3 in the differential diagnosis and prognosis of nonsmall cell lung cancer. Materials and methods: The expression of Napsin-A, NTRK-1, NTRK-2, and Desmoglein-3 was examined by immunohistochemistry in 50 squamous cell carcinomas and 50 adenocarcinomas. Desmocollin-3 was investigated in 29 squamous cell carcinoma and 29 adenocarcinoma cases. Associations between expression profiles of Napsin-A, NTRK-1, NTRK-2, Desmoglein-3, and Desmocollin-3 in lung cancers and clinicopathological variables were analyzed. Results: Napsin-A staining was statistically significant in detecting adenocarcinomas versus squamous cell carcinomas. The sensitivity of Napsin-A for adenocarcinomas was …

Go to article

Importance Of Sonographic Paratracheal Lymph Node Evaluationin Early Autoimmune Thyroiditis, Tuğrul Örmeci̇, Mukaddes Çolakoğullari, İsrafi̇l Orhan, Bayram Ufuk Şakul Jan 2016

Importance Of Sonographic Paratracheal Lymph Node Evaluationin Early Autoimmune Thyroiditis, Tuğrul Örmeci̇, Mukaddes Çolakoğullari, İsrafi̇l Orhan, Bayram Ufuk Şakul

Turkish Journal of Medical Sciences

Background/aim: To review the sonographic views of paratracheal lymph nodes (PLNs) in the diagnosis and during different stages of autoimmune thyroiditis. Materials and methods: Features of the PLNs (left and right), thyroid sonography, and laboratory data were investigated in 126 cases. Patients were divided into three groups by using thyroid sonographic criteria in the literature (group 1: control, group 2: early-stage/indeterminate, group 3: definite thyroiditis). Indeterminate patients were followed up for 1 year and included as indeterminate/early-stage thyroiditis patients. Results: Percentage of right and left PLN was 13.3% and 46.2% in control cases, 21.2% and 80% in early-stage/indeterminate cases, and …

Go to article

Association Of Neutrophil/Lymphocyte Ratio With The Degree Ofinterstitial Lung Disease In Systemic Sclerosis, Nurhan Ati̇lla, Gözde Yildirim Çeti̇n, Ayşe Balkarli Jan 2016

Association Of Neutrophil/Lymphocyte Ratio With The Degree Ofinterstitial Lung Disease In Systemic Sclerosis, Nurhan Ati̇lla, Gözde Yildirim Çeti̇n, Ayşe Balkarli

Turkish Journal of Medical Sciences

Background/aim: Determining the severity of systemic sclerosis related interstitial lung disease (SSc-ILD) is based on clinical and radiological findings, inflammation marker levels, and carbon monoxide diffusing capacity of the lung (DLCO). Recently studies are ongoing for objective and easy markers. Neutrophil/lymphocyte ratio (NLR) is shown to be a good marker for inflammation in recent clinical trials. In this study, we aimed to identify the possible relationship between NLR and carbon monoxide transfer coefficient (KCO) of SSc-ILD patients. Materials and methods: Fifty-nine patients with systemic sclerosis (SSc) were enrolled in the study. We used high-resolution computed tomography for diagnosis and used …

Go to article

Exploring Cyp2b6 Activity By Measuring The Presence Ofnevirapine Hydroxy Metabolites In Plasma, Suzana Mustafa, Norul Badriah Hassan, Soo Choon Tan, Mahiran Mustafa, Ahmad Kashfi Ab Rahman, Lee Lee Low, Wan Nazirah Wan Yusuf Jan 2016

Exploring Cyp2b6 Activity By Measuring The Presence Ofnevirapine Hydroxy Metabolites In Plasma, Suzana Mustafa, Norul Badriah Hassan, Soo Choon Tan, Mahiran Mustafa, Ahmad Kashfi Ab Rahman, Lee Lee Low, Wan Nazirah Wan Yusuf

Turkish Journal of Medical Sciences

Background/aim: Nevirapine is a reverse-transcriptase inhibitor widely used in combination therapy to treat HIV infection. Nevirapine is extensively metabolized in the liver and CYP2B6 is mainly responsible for oxidation of 3-hydroxynevirapine (3-OH NVP). This study aims to explore CYP2B6 activity by measuring 2-hydroxynevirapine (2-OH NVP) and 3-OH NVP in plasma and to identify factors associated with nevirapine pharmacokinetic parameters. Materials and methods: A total of 112 patients were recruited and treated with nevirapine-based antiretroviral therapy. Plasma nevirapine and metabolite concentrations were assayed using high-performance liquid chromatography via liquid-liquid extraction. Results: Thirty-nine (34.8%) of the patients had no 3-OH NVP detected …

Go to article

Peripheral Flt-3 Ligand Levels As A Pathobiological Parameter Duringthe Clinical Course Of Acute Myeloid Leukemia, Memduh Şahi̇n, İbrahi̇m Celaletti̇n Haznedaroğlu, Demi̇rcan Özbalci Jan 2016

Peripheral Flt-3 Ligand Levels As A Pathobiological Parameter Duringthe Clinical Course Of Acute Myeloid Leukemia, Memduh Şahi̇n, İbrahi̇m Celaletti̇n Haznedaroğlu, Demi̇rcan Özbalci

Turkish Journal of Medical Sciences

Background/aim: FLT-3 ligand is a growth factor affecting the hematopoietic lineage. The aim of this study was to evaluate the variability of peripheral FLT-3 ligand during the clinical course of acute myeloid leukemia (AML) patients. Materials and methods: Twenty-four patients were enrolled in this study in order to assess alterations in the circulating levels of FLT-3 ligand during the clinical course of AML. Results: We studied the association in the diagnostic period between the FLT-3 ligand and peripheral blood cells together with serum electrolytes. FLT-3 ligand levels (pg/mL) during the aplastic period due to remission induction and consolidation were higher …

Go to article

Growing Oxa-23 Type Strains Among Carbapenem-Resistant Acinetobacter Baumannii And Tigecycline As An Alternate Combination Therapy, Şeri̇fe Altun, Zeli̇ha Koçak Tufan, Belgi̇n Altun, Ufuk Önde, Sami̇ Kinikli, Ali̇ Pekcan Demi̇röz Jan 2016

Growing Oxa-23 Type Strains Among Carbapenem-Resistant Acinetobacter Baumannii And Tigecycline As An Alternate Combination Therapy, Şeri̇fe Altun, Zeli̇ha Koçak Tufan, Belgi̇n Altun, Ufuk Önde, Sami̇ Kinikli, Ali̇ Pekcan Demi̇röz

Turkish Journal of Medical Sciences

Background/aim: The increasing prevalence and global spread of difficult-to-treat carbapenem-resistant Acinetobacter baumannii has become a serious problem. The aim of this study is to investigate the resistance patterns and tigecycline sensitivity of carbapenem-resistant A. baumannii strains. Materials and methods: Acinetobacter strains that were carbapenem-resistant and collected mainly from intensive care units were included into this study. The antibiotic sensitivity/resistance of the strains to other antibiotics and tigecycline were noted. Presence of blaOXA-23, blaOXA-48, blaOXA58, and NDM-1 was investigated by PCR. Results: In total, 44 carbapenem-resistant A. baumannii strains were detected. In addition, 57% (25/44) showed resistance to netilmicin and 2% …

Go to article

The Effect Of Basolateral Amygdala Nucleus Lesion On Memory Under Acute,Mid And Chronic Stress In Male Rats, Hoda Ranjbar, Maryam Radahmadi, Hojjatallah Alaei, Parham Reisi, Sara Karimi Jan 2016

The Effect Of Basolateral Amygdala Nucleus Lesion On Memory Under Acute,Mid And Chronic Stress In Male Rats, Hoda Ranjbar, Maryam Radahmadi, Hojjatallah Alaei, Parham Reisi, Sara Karimi

Turkish Journal of Medical Sciences

Background/aim: The basolateral amygdala (BLA) modulates memory for emotional events and is involved in both stress and memory. This study investigated different durations of stress and the role of BLA on serum corticosterone level and spatial and cognitive memory. Materials and methods: Different durations of stress (acute, mid, and chronic stress), with and without BLA lesion were induced in rats by 6 h/day restraint stress for 1, 7, and 21 days. Memory functions were evaluated by novel object recognition (NOR) and object location test (OLT). Results: The OLT findings showed locomotor activity and spatial memory slightly decreased with different durations …

Go to article

Chrysin Prevents Brain Damage Caused By Global Cerebralischemia/Reperfusion In A C57bl/J6 Mouse Model, Mehmet Aki̇f Durak, Mustafa Namik Öztanir, Neşe Başak Türkmen, Osman Çi̇ftçi̇, Asli Taşlidere, Mehmet Tecelli̇oğlu, Ari̇f Önder Jan 2016

Chrysin Prevents Brain Damage Caused By Global Cerebralischemia/Reperfusion In A C57bl/J6 Mouse Model, Mehmet Aki̇f Durak, Mustafa Namik Öztanir, Neşe Başak Türkmen, Osman Çi̇ftçi̇, Asli Taşlidere, Mehmet Tecelli̇oğlu, Ari̇f Önder

Turkish Journal of Medical Sciences

Background/aim: The present study investigated the neuroprotective effects of chrysin (CRS) following global cerebral ischemia and reperfusion (I/R) in a C57BL/J6 mouse model. Materials and methods: A total of 40 mice were equally divided into four groups: (1) sham-operated (SH = control), (2) global cerebral I/R (I/R), (3) CRS, and (4) CRS + I/R. In the I/R group, the bilateral carotid arteries were clipped for 15 min and the mice were treated with vehicle (corn oil) for 10 days. In the CRS group, CRS (50 mg/kg) was given for 10 days without carotid occlusion. In the CRS + I/R group …

Go to article

Identifying And Accommodating Education And Research Barriers Of Rural Nursing Staff In The Mississippi River Delta, Anna Watkins Jan 2016

Identifying And Accommodating Education And Research Barriers Of Rural Nursing Staff In The Mississippi River Delta, Anna Watkins

Doctor of Nursing Practice Projects

The purpose of this cross sectional descriptive study is to identify, by survey, what education and research barriers exist for operating room and post anesthesia care nursing staff in the rural hospitals of the Mississippi River Delta.

Go to article

Identifying And Accommodating Education And Research Barriers Of Rural Nursing Staff In The Mississippi River Delta, L. Todd Hammon Jan 2016

Identifying And Accommodating Education And Research Barriers Of Rural Nursing Staff In The Mississippi River Delta, L. Todd Hammon

Doctor of Nursing Practice Projects

Nearly 20% of the nursing workforce practice in rural settings. The literature suggest rural nursing staff do not have the same opportunities for continuing education or the implementation of research in their practice as do nursing staff of larger urban hospitals. Rural nursing staff face unique barriers in obtaining the needed continuing education and research. Identifying and accommodating these barriers is needed. The purpose of this study was to identify by survey, what education and research barriers exist for operating room and post anesthesia care nursing staff in the rural hospitals of the Mississippi River Delta.

Go to article

Oral Manifestations Of Menopause: An Interprofessional Intervention For Dental Hygiene And Physician Assistant Students, Windy L. Rothmund Jan 2016

Oral Manifestations Of Menopause: An Interprofessional Intervention For Dental Hygiene And Physician Assistant Students, Windy L. Rothmund

EWU Masters Thesis Collection

"Purpose: Interprofessional education (IPE) is a means of fostering integration and collaboration between health care professions. This study evaluated the effect of an IPE educational module on the oral manifestations of menopause. Methods: This mixed-method study used a convenience sample of dental hygiene (DH) and physician assistants (PA) students. Pre- and posttests collected quantitative data using a modified Readiness for Interprofessional Learning Survey (RIPLS), and a PI-designed knowledge of menopause test to determine students attitudes and learning. Students participated in a one-time workshop that included an educational lecture and a case study exercise using a pseudo-standardized patient. Students worked in …

Go to article

Emergency Department Visits Caused By Adverse Drug Reactions: Results Of Aturkish University Hospital, Mehmet Can Gi̇rgi̇n, Sedat Yanturali, Mualla Ayli̇n Arici, Neşe Çolak Oray, Özgür Doylan, Yücel Demi̇ral, Yeşi̇m Tunçok Jan 2016

Emergency Department Visits Caused By Adverse Drug Reactions: Results Of Aturkish University Hospital, Mehmet Can Gi̇rgi̇n, Sedat Yanturali, Mualla Ayli̇n Arici, Neşe Çolak Oray, Özgür Doylan, Yücel Demi̇ral, Yeşi̇m Tunçok

Turkish Journal of Medical Sciences

Background/aim: We aimed to evaluate adverse drug reaction (ADR)-related emergency department (ED) visits in the ED of the Dokuz Eylül University Hospital prospectively. Materials and methods: Patients who were admitted to the ED during 1-week periods of four different seasons between July 2010 and April 2011 were enrolled. Demographics of patients, previous ADR history, clinical progress, and outcomes were recorded. Causality assessment was done according to World Health Organization Uppsala Monitoring Centre categories. ADRs were categorized as certain, probable, or possible. Results: Patients who were on medications (26.5%, n = 1838) were evaluated for ADR-related ED admissions. ADRs accounted for …

Go to article

Evaluation Of Brainstem Auditory Evoked Potentials And Their Relationshipwith Levels Of Thyroid Autoantibodies In Patients With Vitiligo, İlhan Çeçen, Ayşe Serap Karadağ, Temel Tombul, Serap Güneş Bi̇lgi̇li̇, Ömer Çalka, Ahmet Zübeyi̇r Burakgazi̇ Jan 2016

Evaluation Of Brainstem Auditory Evoked Potentials And Their Relationshipwith Levels Of Thyroid Autoantibodies In Patients With Vitiligo, İlhan Çeçen, Ayşe Serap Karadağ, Temel Tombul, Serap Güneş Bi̇lgi̇li̇, Ömer Çalka, Ahmet Zübeyi̇r Burakgazi̇

Turkish Journal of Medical Sciences

Background/aim: Vitiligo is a common depigmenting disorder. The damage can also occur in similar ways to melanocytes within other organs. We evaluated the brainstem and auditory pathway functions by evaluating brainstem auditory evoked potentials (BAEPs) and whether there is any relationship between auditory functions and autoimmunity. Materials and methods: Forty patients with vitiligo and 20 healthy volunteers were enrolled. Thyroid functions and autoantibodies were examined and BAEP tests were assessed by a neurologist. Results: Antithyroid peroxidase (anti-TPO) and antithyroglobulin (anti-TGA) antibody positivity was higher in the patient group (P < 0.05). A negative correlation was detected between anti-TPO and lead III, IV, and V latency and I?III interpeak latency (IPL) of the right ear together with lead IV latency and I?V IPL of the left ear in the patient group. When each BAEP parameter was compared between the two groups, more abnormalities were detected in the V latency and III?V IPL of the left ear together with IV and V latency of the right ear. Conclusion: In this study the presence of a correlation between increased anti-TGA and anti-TPO levels and BAEP parameters may be related to an autoimmune-mediated mechanism. However, further studies are needed to be performed in a large patient series.

Go to article

Mefv Mutations In Iranian Azari Turkish Patients With Henoch?Schönlein Purpura, Mortaza Bonyadi, Mahdieh Younesi, Mandana Rafeey, Mahnaz Sadeghi_Shabestari, Fakhrossadat Mortazavi Jan 2016

Mefv Mutations In Iranian Azari Turkish Patients With Henoch?Schönlein Purpura, Mortaza Bonyadi, Mahdieh Younesi, Mandana Rafeey, Mahnaz Sadeghi_Shabestari, Fakhrossadat Mortazavi

Turkish Journal of Medical Sciences

Background/aim: The aim of the current study was to screen the rate of MEFV mutations in Henoch?Schönlein purpura (HSP) and to investigate the association of these mutations plus clinical symptoms with HSP disease in the Iranian Azari Turkish ethnic group. Materials and methods: The study groups included 40 unrelated HSP patients and 200 apparently healthy people without any kind of inflammatory diseases as a control group. Molecular screening was performed for eight main mutations, namely M694V, M694I, M680I, V726A, E148Q, R761H, P396S, and R408Q, using polymerase chain reaction (PCR), restriction fragment length polymorphism (RFLP), and sequencing. Results: Out of the …

Go to article

The Relationship Between Blood Urea Nitrogen Levels And Metabolic, Biochemical, And Histopathologic Findings Of Nondiabetic, Nonhypertensive Patients With Nonalcoholic Fatty Liver Disease, Cemal Nuri̇ Erçi̇n, Teoman Doğru, Gürkan Çelebi̇, Hasan Gürel, Hali̇l Genç, Erdi̇m Sertoğlu, Sai̇t Bağci Jan 2016

The Relationship Between Blood Urea Nitrogen Levels And Metabolic, Biochemical, And Histopathologic Findings Of Nondiabetic, Nonhypertensive Patients With Nonalcoholic Fatty Liver Disease, Cemal Nuri̇ Erçi̇n, Teoman Doğru, Gürkan Çelebi̇, Hasan Gürel, Hali̇l Genç, Erdi̇m Sertoğlu, Sai̇t Bağci

Turkish Journal of Medical Sciences

Background/aim: Nonalcoholic fatty liver disease (NAFLD) is known as the most common cause of chronic liver disease. It is accepted that the leading cause of death in patients with NAFLD is from coronary events. Blood urea nitrogen (BUN) was used as a prognostic indicator for cardiovascular disease. We aimed to investigate the relationship between BUN levels and metabolic, biochemical, and histopathologic findings of nondiabetic patients with NAFLD. Materials and methods: A total of 195 male patients with biopsy proven NAFLD and 82 healthy controls with normal liver and renal function tests and normal abdominal ultrasonography were enrolled in the study. …

Go to article

Health Promotion Lifestyle Profile Scores Are Not Associatedwith Obesity In High School Students, Gi̇zem Li̇mni̇li̇, Ni̇lgün Özçakar, Mehtap Kartal Jan 2016

Health Promotion Lifestyle Profile Scores Are Not Associatedwith Obesity In High School Students, Gi̇zem Li̇mni̇li̇, Ni̇lgün Özçakar, Mehtap Kartal

Turkish Journal of Medical Sciences

Background/aim: Obesity is a cause of preventable morbidity and mortality with an increasing prevalence. Health promoting lifestyle activities maintain or improve an individual?s health and in adolescence many habits are configured. The aim of this study was to determine the prevalence of overweight and obesity among adolescents and the relation between obesity and health promoting behaviors. Materials and methods: This is a cross-sectional study including 848 high school students aged 15?17. All students were administered a questionnaire including the Health Promotion Life-Style Profile Scale. Weight and height were measured and body mass index was calculated. Descriptive analysis, Pearson?s chi-square test, …

Go to article

First Prev Next Last