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2015

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Articles 9721 - 9750 of 11981

Full-Text Articles in Medicine and Health Sciences

Correlation Between Antibiotic Resistance And Virulence Ofpseudomonas Aeruginosa Clinical Isolates, Fatma Ibrahim Sonbol, Maha Abd El Fattah Khalil, Abdelfattah Badr Mohamed, Sameh Samir Ali Jan 2015

Correlation Between Antibiotic Resistance And Virulence Ofpseudomonas Aeruginosa Clinical Isolates, Fatma Ibrahim Sonbol, Maha Abd El Fattah Khalil, Abdelfattah Badr Mohamed, Sameh Samir Ali

Turkish Journal of Medical Sciences

Background/aim: Virulent Pseudomonas aeruginosa is frequently life-threatening and often challenging to treat, and the emergence of multidrug-resistant isolates presents a critical problem for patients. The aim of the study was concerned with molecular analysis of the virulence factors and antimicrobial resistance profile of multidrug-resistant P. aeruginosa (MDRPA). Materials and methods: Out of 44 MDRPA isolates, 12 isolates representing different resistance profiles and sources of samples were selected for further molecular studies. Polymerase chain reaction (PCR) approaches were applied to identify the genes implicated in antimicrobial resistance or virulence factors in the selected MDRPA isolates. Results: Multidrug-resistance (pstS), ß-lactamase (IMP7, IMP10, …

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Comparison Of The Contamination Rates Of Culture Media Used For Isolation And Identification Of Dermatophytes, Ramazan Gümral, Ayli̇n Döğen, Mehmet Maci̇t İlki̇t Jan 2015

Comparison Of The Contamination Rates Of Culture Media Used For Isolation And Identification Of Dermatophytes, Ramazan Gümral, Ayli̇n Döğen, Mehmet Maci̇t İlki̇t

Turkish Journal of Medical Sciences

Background/aim: Mycological media that promote spore production are essential for the diagnosis of dermatophytosis. However, these culture media frequently become contaminated by multiple fungal or bacterial species during culture. The aim of this study was to compare the contamination rates of 6 culture media used for the isolation and identification of dermatophytes, including Borelli's lactritmel agar (BLA), brain-heart infusion agar (BHIA), Lowenstein-Jensen agar (LJA), malt extract agar (MEA), potato dextrose agar (PDA), and Sabouraud glucose agar (SGA). Materials and methods: Agar plates were inoculated with 43 well-characterized dermatophyte strains, belonging to the genera Arthroderma, Epidermophyton, Microsporum, or Trichophyton. The agar …

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Elevated Serum Matrix Metalloproteinase-2 And -9 And Their Correlationswith Severity Of Disease In Patients With Community-Acquired Pneumonia, Haci Ahmet Bi̇rcan, Müni̇re Çakir, İlkay Yilmazer Kapulu, Recep Sütcü, Selçuk Kaya, Önder Öztürk Jan 2015

Elevated Serum Matrix Metalloproteinase-2 And -9 And Their Correlationswith Severity Of Disease In Patients With Community-Acquired Pneumonia, Haci Ahmet Bi̇rcan, Müni̇re Çakir, İlkay Yilmazer Kapulu, Recep Sütcü, Selçuk Kaya, Önder Öztürk

Turkish Journal of Medical Sciences

Background/aim: To determine the role of matrix metalloproteinases (MMPs) and their relationship with the clinical course of community-acquired pneumonia (CAP). Materials and methods: Sixty-two consecutively hospitalized patients with CAP were enrolled and their pneumonia severity index (PSI), time to clinical stability (TCS), treatment response, and complications were recorded. The pre- and posttreatment serum concentrations of MMPs and their inhibitors were analyzed by ELISA. The activities of MMPs were evaluated by gelatin zymography. Results: MMP-2 and -9 serum levels and their activities were higher in CAP patients than controls (P < 0.001 and P < 0.001, respectively). Low-risk patients had lower levels of MMP-2 and TIMP-1 than high-risk patients (P = 0.044, P = 0.001, respectively). Pretreatment serum TIMP-1 level was higher in patients with TCS of >3 days (P = 0.004) and was correlated with oxygenation and …

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Correlation Between Serum Levels Of Vitamin B12 And Anti-Helicobacter Pyloriiga Antibodies In Vitamin B12 Deficient Palestinian Patients, Rasmi Abu Hilu, Osama Dudeen, Sameer Abdullatif Barghouthi Jan 2015

Correlation Between Serum Levels Of Vitamin B12 And Anti-Helicobacter Pyloriiga Antibodies In Vitamin B12 Deficient Palestinian Patients, Rasmi Abu Hilu, Osama Dudeen, Sameer Abdullatif Barghouthi

Turkish Journal of Medical Sciences

Background/aim: H. pylori infection and vitamin B12 (vB12) deficiency have high prevalence rates among Palestinians. It was observed that most people who suffered from vB12 deficiency were positive for H. pylori. Materials and methods: The correlation between H. pylori infection and vB12 deficiency was investigated in a representative segment of the Palestinian population. ELISA was used to determine levels of vitamin B12 (vB12) and anti-H. pylori IgA in sera from 238 participants from Al-Khalil district (Hebron), Palestine. Results: There was a strong negative Pearson's correlation coefficient (r = -0.45; P = 0.00001) between levels of anti-H. pylori IgA and vB12 …

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Sp1 Binding Site Polymorphism Of A Collagen Gene (Rs 1800012) In Womenaged 45 And Over And Its Association With Bone Density, Morteza Dehghan, Razieh Pourahmad-Jaktaji Jan 2015

Sp1 Binding Site Polymorphism Of A Collagen Gene (Rs 1800012) In Womenaged 45 And Over And Its Association With Bone Density, Morteza Dehghan, Razieh Pourahmad-Jaktaji

Turkish Journal of Medical Sciences

Background/aim: Sp1 polymorphism of type I collagen genes is accompanied with bone c??ollagen disorders and severe clinical phenotypes such as osteogenesis imperfecta. The aim of this study was to study the association between COLIA1 Sp1 polymorphism and bone density rate. Materials and methods: In this descriptive, analytical study conducted in 2013 in southwestern Iran, 200 blood samples, per the Cochran sample size formula, were taken from women aged 45 and older. DNA was extracted from the samples using the phenol-chloroform method and the genomic fragments in question were proliferated using the polymerase chain reaction (PCR) method. Results: The genotype distribution …

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The Hematologic Manifestations Of Pediatric Celiac Disease At The Time Ofdiagnosis And Efficiency Of Gluten-Free Diet, Ferat Çatal, Erdem Topal, Hali̇me Ermi̇şteki̇n, Nurdan Yildirim Acar, Muhammed Selçuk Si̇nanoğlu, Hamza Karabi̇ber, Mukadder Ayşe Seli̇moğlu Jan 2015

The Hematologic Manifestations Of Pediatric Celiac Disease At The Time Ofdiagnosis And Efficiency Of Gluten-Free Diet, Ferat Çatal, Erdem Topal, Hali̇me Ermi̇şteki̇n, Nurdan Yildirim Acar, Muhammed Selçuk Si̇nanoğlu, Hamza Karabi̇ber, Mukadder Ayşe Seli̇moğlu

Turkish Journal of Medical Sciences

Background/aim: To determine the hematologic manifestations at the time of diagnosis of celiac disease in children and the effects of a gluten-free diet on hematologic signs upon follow-up. Materials and methods: The records of patients with celiac disease who received a follow up examination at the Pediatric Gastroenterology Clinic between June 2006 and June 2013 were retrospectively examined. Results: Ninety-one patients were included in the study. The mean age at diagnosis was 8.1 ± 4.21 years and 59 patients (64.8%) were female. Thirty-two patients (35.2%) had hematologic signs at the time of diagnosis. Anemia (24.2%) was the most common hematologic …

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Serologic Testing For Celiac Disease In Young People With Elevated Transaminases, Juanli Yuan, Jinyan Gao, Yonghong Yao, Hongbing Chen Jan 2015

Serologic Testing For Celiac Disease In Young People With Elevated Transaminases, Juanli Yuan, Jinyan Gao, Yonghong Yao, Hongbing Chen

Turkish Journal of Medical Sciences

Background/aim: A cryptogenic elevation of transaminases is the most common hepatic manifestation in celiac disease (CD). In adult patients and pediatric patients with cryptogenic hypertransaminasemia, the prevalence of CD was 4% and 12%, respectively. However, there are no related data from China in this regard. We aimed to investigate the status of CD in young Chinese patients with elevated transaminases. Materials and methods: A total of 125 patients with elevated transaminases and 125 healthy individuals as controls with matched age and sex were involved in the study. Serum markers of hepatitis B were determined in patients with elevated transaminases. All …

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Efficacy Of Diffusion-Weighted Magnetic Resonance Imaging In The Evaluation Of Extrahepatic Cholestasis-Related Hepatic Fibrosis, Süleyman Ayvaz, Sedat Alpaslan Tuncel, Güray Can, Beki̇r Çağli, Turan Karaca, Seli̇m Demi̇rtaş, Muhammed Elmaoğlu, Mehmet Ercüment Ünlü, Mehmet Pul Jan 2015

Efficacy Of Diffusion-Weighted Magnetic Resonance Imaging In The Evaluation Of Extrahepatic Cholestasis-Related Hepatic Fibrosis, Süleyman Ayvaz, Sedat Alpaslan Tuncel, Güray Can, Beki̇r Çağli, Turan Karaca, Seli̇m Demi̇rtaş, Muhammed Elmaoğlu, Mehmet Ercüment Ünlü, Mehmet Pul

Turkish Journal of Medical Sciences

Background/aim: To investigate the efficacy of diffusion-weighted magnetic resonance imaging (DWI) in the diagnosis and staging of fibrosis induced by experimental bile duct ligation (BDL). Materials and methods: Twenty-four rats were divided randomly into four groups: control, BDL - 3 days, BDL - 2 weeks, and BDL - 4 weeks. DWI was performed with b-values of 100 and 500 on the rats from control group at day zero, on the rats from the BDL - 3 days group at the end of day 3, on the rats from the BDL - 2 weeks group at the end of day 14, …

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Comparison Of Local Infiltration Anesthesia And Peripheral Nerve Block:A Randomized Prospective Study In Hand Lacerations, Alp Şener, Ahmet Demi̇rcan, Ayfer Keleş, Fi̇kret Bi̇ldi̇k, Kanber Karakurt Jan 2015

Comparison Of Local Infiltration Anesthesia And Peripheral Nerve Block:A Randomized Prospective Study In Hand Lacerations, Alp Şener, Ahmet Demi̇rcan, Ayfer Keleş, Fi̇kret Bi̇ldi̇k, Kanber Karakurt

Turkish Journal of Medical Sciences

Background/aim: To compare local infiltration anesthesia (LIA) and peripheral nerve block (PNB) in repairing hand lacerations. Materials and methods: This prospective study was designed as a randomized, controlled, unblinded trial. Fifty four patients with hand lacerations were included in the study. While 23 of these patients had LIA, PNB was performed in the remaining 31 patients. Lidocaine hydrochloride 2% and 27 gauge needles were used. Onset time of the anesthesia, response to the injection and suturing procedures, need for additional anesthetic, and patient satisfaction were compared. Results: No significant differences were noted between the groups in terms of response to …

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Efficacy Of Wound Infiltration With Lornoxicam For Postoperative Analgesiafollowing Thyroidectomy: A Prospective, Randomized, Double-Blind Study, Zafer Kilbaş, Mustafa Öner Menteş, Ali̇ Harlak, Taner Yi̇ği̇t, Sali̇h Müjdat Balkan, Ahmet Coşar, Erkan Öztürk, Orhan Kozak, Cemi̇l Turgut Tufan Jan 2015

Efficacy Of Wound Infiltration With Lornoxicam For Postoperative Analgesiafollowing Thyroidectomy: A Prospective, Randomized, Double-Blind Study, Zafer Kilbaş, Mustafa Öner Menteş, Ali̇ Harlak, Taner Yi̇ği̇t, Sali̇h Müjdat Balkan, Ahmet Coşar, Erkan Öztürk, Orhan Kozak, Cemi̇l Turgut Tufan

Turkish Journal of Medical Sciences

Background/aim: Postoperative pain control constitutes a major problem and studies have focused on reducing opioid requirements using regional techniques. We aimed to investigate the efficacy of wound infiltration with lornoxicam on postoperative pain control following thyroidectomy. Materials and methods: In this prospective, randomized-controlled study, 80 patients scheduled for thyroidectomy were randomly assigned to 2 groups. After the thyroidectomy was performed, patients in group I underwent wound infiltration with 4 mg of lornoxicam and patients in group II received the same amount of saline. Rescue analgesia was provided with additional doses of lornoxicam delivered by an on-demand patient-controlled analgesia device. Total …

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Fetal Health Locus Of Control In A Sample Of Pregnant Turkish Women, Sevgi̇ Özcan, Veli̇ Duyan Jan 2015

Fetal Health Locus Of Control In A Sample Of Pregnant Turkish Women, Sevgi̇ Özcan, Veli̇ Duyan

Turkish Journal of Medical Sciences

Background/aim: To examine the relationship between sociodemographic and pregnancy features and fetal health locus of control (FHLC) in a sample of pregnant Turkish women. Materials and methods: The study was conducted with 256 pregnant women. Data were collected by demographic questionnaire and the FHLC Scale consisting of 3 components: 1) Internality Scale (FHLC-I), 2) Powerful Others Scale (FHLC-P), and 3) Chances Scale (FHLC-C). Results: The age of marriage was found to have a positive relation with FHLC-I (r = 0.141) and a negative relation with FHLC-C (r = -0.145) (P < 0.05). The age of first pregnancy was found to have a positive relation with FHLC-I (r = 0.127). Those who have a low educational level (r = -0.258) and income (r = -0.149), who are unemployed (r = -2.839), whose number of pregnancies is high (r = 0.152), who get pregnant unplanned (r = 3.839), and who come to their first prenatal examination late (r = -0.142) have a significantly high score of FHLC-C (P

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Intrahepatic Cholestasis Of Pregnancy May Lead To Low Birth Weight, İbrahi̇m Uyar, İbrahi̇m Gülhan, Deni̇z Özteki̇n, Cenk Gezer, Atalay Eki̇n, Seçi̇l Karaca Kurtulmuş, Mehmet Özeren Jan 2015

Intrahepatic Cholestasis Of Pregnancy May Lead To Low Birth Weight, İbrahi̇m Uyar, İbrahi̇m Gülhan, Deni̇z Özteki̇n, Cenk Gezer, Atalay Eki̇n, Seçi̇l Karaca Kurtulmuş, Mehmet Özeren

Turkish Journal of Medical Sciences

Background/aim: To evaluate patients hospitalized in our clinic in the last 5 years with the diagnosis of intrahepatic cholestasis of pregnancy (ICP). Materials and methods: One hundred and fifty patients hospitalized with a diagnosis of ICP between January 2008 and May 2013 were evaluated retrospectively and age, week at diagnosis, gestational age at delivery, period between diagnosis and delivery, fetal weight, transaminases, and coagulation parameters were recorded. Patients were divided into groups according to their diagnosis weeks and gravida. Accordingly, patients diagnosed before 32 weeks formed group A (n = 49) and those after 32 weeks formed group B (n …

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Distribution And Antifungal Resistance Of Candida Speciesisolated From Intensive Care Units, Pinar Korkmaz, Yeşi̇m Alpay, Fi̇gen Çevi̇k, Nevi̇l Aykin, Ayşe Koygun, Hakki Mustafa Güldüren Jan 2015

Distribution And Antifungal Resistance Of Candida Speciesisolated From Intensive Care Units, Pinar Korkmaz, Yeşi̇m Alpay, Fi̇gen Çevi̇k, Nevi̇l Aykin, Ayşe Koygun, Hakki Mustafa Güldüren

Turkish Journal of Medical Sciences

No abstract provided.

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Myelodysplastic Features And Cellular Senescence In Autoimmune Disorders: A Pilot Study On Patients With Collagen Tissue Disorders And Immune Thrombocytopenic Purpura, Lale Olcay, Deni̇z Bi̇llur, Esra Erdemli̇, Sidika Esra Baskin, Havva Fatma Balci, Sevgi̇ Yetgi̇n Jan 2015

Myelodysplastic Features And Cellular Senescence In Autoimmune Disorders: A Pilot Study On Patients With Collagen Tissue Disorders And Immune Thrombocytopenic Purpura, Lale Olcay, Deni̇z Bi̇llur, Esra Erdemli̇, Sidika Esra Baskin, Havva Fatma Balci, Sevgi̇ Yetgi̇n

Turkish Journal of Medical Sciences

No abstract provided.

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The Evaluation Of Transient Hypothyroidism In Patients Diagnosedwith Congenital Hypothyroidism, Havva Nur Peltek Kendi̇rci̇, Zehra Aycan, Eli̇f Sağsak, Meli̇kşah Keski̇n, Semra Çeti̇nkaya Jan 2015

The Evaluation Of Transient Hypothyroidism In Patients Diagnosedwith Congenital Hypothyroidism, Havva Nur Peltek Kendi̇rci̇, Zehra Aycan, Eli̇f Sağsak, Meli̇kşah Keski̇n, Semra Çeti̇nkaya

Turkish Journal of Medical Sciences

Background/aim: Congenital hypothyroidism (CH) is divided into two groups as 'permanent' and 'transient'. We aimed to determine the rate of transient and permanent congenital hypothyroidism of the newborns referred to our clinic. Materials and methods: Of the newborns who were referred to our clinic from the neonatal screening program, those who were diagnosed with CH and started treatment were included in the study. The treatments of the patients whose required daily treatment dose was reduced to under 1 µg/kg were terminated and those who were followed monthly and whose fT4 and thyroid-stimulating hormone (TSH) levels were normal at least 3 …

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Bilateral Sympathicotomy For Hyperhidrosis Without Using Single-Lung Ventilation, Tevfi̇k Kaplan, Peri̇han Ekmekçi̇, Bülent Koçer, Serdar Han Jan 2015

Bilateral Sympathicotomy For Hyperhidrosis Without Using Single-Lung Ventilation, Tevfi̇k Kaplan, Peri̇han Ekmekçi̇, Bülent Koçer, Serdar Han

Turkish Journal of Medical Sciences

Background/aim: The goal of this retrospective study was to evaluate the outcomes and complications of bilateral videothoracoscopic sympathicotomy without using single-lung ventilation in the treatment of primary hyperhidrosis and facial blushing. Materials and methods: We retrospectively reviewed 154 consecutive patients (70 females and 84 males) who underwent bilateral sympathicotomy for palmar, axillary, and facial/scalp hyperhidrosis or facial blushing from February 2005 to June 2013. The patients were intubated with single-lumen endotracheal tube, and then sympathicotomies were performed via videothoracoscopy during controlled apnea periods. Results: Sympathicotomies were performed at costal levels 2, 3, and 4. No perioperative mortality or conversion to …

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Self-Perception Of Quality Of Life In Patients Treated With Antipsychotics, Lorena Dima, Daniel Vasile, Liliana Rogozae, Muhammad Zia-Ul-Haq, Shazia Anwer Bukhari, Marius Moga Jan 2015

Self-Perception Of Quality Of Life In Patients Treated With Antipsychotics, Lorena Dima, Daniel Vasile, Liliana Rogozae, Muhammad Zia-Ul-Haq, Shazia Anwer Bukhari, Marius Moga

Turkish Journal of Medical Sciences

Background/aim: Despite extensive research, normal functionality remains problematic in patients with schizophrenia. Issues such as quality of life, subjective well-being, or psychosocial performance are currently objectives of interest. There are limited data collected prospectively on patients' perception of quality of life as compared between treatment groups, especially in developing countries. The aim of the present study was to analyze the evolution of patients' reported quality of life in patients with schizophrenia or related disorders treated with antipsychotics, in naturalistic settings. Materials and methods: The study was designed as a 12-month prospective observational study of 131 subjects with schizophrenia or related …

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Multidrug Resistance And Integron Carriage In Clinical Isolates Ofpseudomonas Aeruginosa In Tehran, Iran, Somayeh Moazami Goudarzi, Fereshteh Eftekhar Jan 2015

Multidrug Resistance And Integron Carriage In Clinical Isolates Ofpseudomonas Aeruginosa In Tehran, Iran, Somayeh Moazami Goudarzi, Fereshteh Eftekhar

Turkish Journal of Medical Sciences

Background/aim: Pseudomonas aeruginosa is the cause of 10% of hospital-acquired infections. The organisms are often multidrug-resistant, mediated mostly by antibiotic-resistant integrons. The aim of this research was to study integron carriage and its association with multidrug resistance in burn and nonburn clinical isolates of P. aeruginosa. Materials and methods: A total of 112 P. aeruginosa clinical isolates were collected from the Motahari and Shohadaye Tajrish hospitals in Tehran between July and December 2011. Antibiotic susceptibility to 13 antibiotics was determined by disk diffusion. Detection of integron classes 1 and 2 and amplifications of internal variable regions (IVRs) of class 1 …

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A Study Of The Effect Of Bacillus Thuringiensis Serotype H14 (Subspecies Israelensis)Delta Endotoxin On Musca Larva, Mohammad Reza Mehrabi, Laya Zoghimofrad, Mahboubeh Mazinani, Azim Akbarzadeh, Amirabbas Rahimi Jan 2015

A Study Of The Effect Of Bacillus Thuringiensis Serotype H14 (Subspecies Israelensis)Delta Endotoxin On Musca Larva, Mohammad Reza Mehrabi, Laya Zoghimofrad, Mahboubeh Mazinani, Azim Akbarzadeh, Amirabbas Rahimi

Turkish Journal of Medical Sciences

Background/aim: House flies (Musca domestica) are of major public health concern in areas with poor sanitation and hygiene conditions. Biological control through the use of parasitoids and pathogens is one of the alternatives to the use of chemical pesticides for control of insects of public health importance. Materials and methods: The effects of the delta endotoxin of Bacillus thuringiensis on house fly larval mortality were studied. Gel filtration and SDS-PAGE methods were used for separation and purification of proteins. Delta endotoxin was incubated with larvae in concentrations of 0.43 mg/mL and 0.27 mg/mL in bioassay tests. Results: The results of …

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Is There A Role Of Interstitial Cells Of Cajal And Mast Cells And Eosinophilsin Appendicitis In Children?, Esra Karakuş, Müjdem Nur Azili, Bi̇lge Karabulut, Gülşah Bayram Kabaçam, Resul Karakuş Jan 2015

Is There A Role Of Interstitial Cells Of Cajal And Mast Cells And Eosinophilsin Appendicitis In Children?, Esra Karakuş, Müjdem Nur Azili, Bi̇lge Karabulut, Gülşah Bayram Kabaçam, Resul Karakuş

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to compare the distribution of interstitial Cajal cells, eosinophils, and mast cells in normal and inflamed appendices, and to evaluate the correlation of presence of these cells with severity of inflammation in appendicitis. Materials and methods: The appendicitis group (n = 30) was divided further into three groups according to the macroscopic description and the histological findings. Ten normal appendices served as controls. Tissue samples were processed for routine histological examination. Additionally, all sections were immunohistochemically stained with CD117 and mast cell tryptase antibodies. Results: When specimens were compared in terms of Cajal …

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The Effects Of Aspirin, Flurbiprofen, And No-Donating Acetylsalicylic Acid(Ncx 4016) On Mice Models Of Endotoxic And Septic Shock, Nadi̇r Ulu, Alper Bektaş İski̇t, Cenk Sökmensüer, Mustafa Oğuz Güç Jan 2015

The Effects Of Aspirin, Flurbiprofen, And No-Donating Acetylsalicylic Acid(Ncx 4016) On Mice Models Of Endotoxic And Septic Shock, Nadi̇r Ulu, Alper Bektaş İski̇t, Cenk Sökmensüer, Mustafa Oğuz Güç

Turkish Journal of Medical Sciences

Background/aim: Nitric oxide-donating nonsteroidal antiinflammatory drugs (NO-NSAIDs) are a promising new class of antiinflammatory agents, which are obtained by adding NO-donating moieties to the existing conventional NSAID molecules. The aim of this study was to investigate the effects of aspirin, flurbiprofen, and NO-donating acetylsalicylic acid (NCX 4016) on cecal ligation and puncture (CLP) and endotoxin-induced septic shock (LPS) models in mice. Materials and methods: Overall survival and spleen and liver weights were monitored in LPS and CLP models. Histopathological examinations of liver and spleen were performed at the end of the experimental protocols. Results: NCX 4016 was able to reverse …

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Epidemiology, Causative Agents, And Risk Factors Affecting Humanotomycosis Infections, Metwally Abdelazeem, Ahmed Gamea, Hanan Mubarak, Nessma Elzawawy Jan 2015

Epidemiology, Causative Agents, And Risk Factors Affecting Humanotomycosis Infections, Metwally Abdelazeem, Ahmed Gamea, Hanan Mubarak, Nessma Elzawawy

Turkish Journal of Medical Sciences

Background/aim: Otomycosis, or fungal otitis externa, has typically been described as fungal infection of the external auditory canal, with infrequent complications involving the middle ear. This study assessed a mycological analysis of fungal debris from external auditory canals of patients at Tanta University Hospital, Gharbia Governorate, Egypt. Materials and methods: The samples were collected over a year from the 110 patients that were clinically diagnosed to have otomycosis. The samples were then inoculated and culture plates were examined for the presence of fungal growth. Results: The results showed that Aspergillus niger was the most common fungus causing otomycosis. It was …

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Effects Of Melatonin And Theanine Administration On Pentylenetetrazole-Inducedseizures And Brain Tissue Oxidative Damage In Ovariectomized Rats, Shadi Choopankareh, Farzaneh Vafaee, Mohammad Naser Shafei, Hamid Reza Sadeghnia, Reza Salarinia, Leila Zarepoor, Mahmoud Hosseini Jan 2015

Effects Of Melatonin And Theanine Administration On Pentylenetetrazole-Inducedseizures And Brain Tissue Oxidative Damage In Ovariectomized Rats, Shadi Choopankareh, Farzaneh Vafaee, Mohammad Naser Shafei, Hamid Reza Sadeghnia, Reza Salarinia, Leila Zarepoor, Mahmoud Hosseini

Turkish Journal of Medical Sciences

Background/aim: The effects of coadministration of melatonin and theanine (Mel/Thea) on pentylenetetrazole (PTZ)-induced seizures and brain tissue oxidative damage were investigated in ovariectomized (OVX) and sham-operated rats. Materials and methods: The rats were divided into the following groups: 1) sham, 2) ovariectomized (OVX), 3) sham-PTZ, 4) OVX-PTZ, 5) sham-Mel/Thea-PTZ, and 6) OVX-Mel/Thea-PTZ. Groups 1-4 received saline, while groups 5 and 6 received a combination of Mel/Thea for 6 weeks. All animals except for those in groups 1 and 2 received a single injection of PTZ. Results: The OVX-PTZ group had higher generalized tonic-clonic seizure (GTCS) latency compared to the sham-PTZ …

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Evaluation Of Gcf Mmp-1, Mmp-8, Tgf-Ss1, Pdgf-Ab, And Vegf Levels In Periodontally Healthy Smokers, Gülni̇hal Eren, Hati̇ce Oya Türkoğlu, Hari̇ka Atmaca, Fatma Gül Ati̇lla Jan 2015

Evaluation Of Gcf Mmp-1, Mmp-8, Tgf-Ss1, Pdgf-Ab, And Vegf Levels In Periodontally Healthy Smokers, Gülni̇hal Eren, Hati̇ce Oya Türkoğlu, Hari̇ka Atmaca, Fatma Gül Ati̇lla

Turkish Journal of Medical Sciences

Background/aim: The effect of smoking on inflammatory biomarkers in gingival crevicular fluid (GCF) is well established in the presence of periodontal inflammation. However, it is not clear if smoking has an influence on matrix metalloproteinase (MMP) and growth factor levels in the GCF of periodontally healthy subjects. The aim of this study was to investigate GCF levels of MMP-1, MMP-8, transforming growth factor (TGF)-ß1, platelet-derived growth factor (PDGF)-AB, and vascular endothelial growth factor (VEGF) in smoking versus nonsmoking periodontally healthy subjects. Materials and methods: Thirty-two periodontally healthy subjects were included in this study. Probing depths, bleeding on probing, and plaque …

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Hepatoprotective And Antioxidant Effects Of Lycopene In Acute Cholestasis, Mehmet Tokaç, Sevtap Aydin, Gökçe Taner, Alper Bi̇lal Özkardeş, Mi̇ne Yavuz Taşlipinar, Mehmet Doğan, Hali̇t Zi̇ya Dündar, Mehmet Kiliç, Ari̇f Ahmet Başaran, Ayşe Nurşen Başaran Jan 2015

Hepatoprotective And Antioxidant Effects Of Lycopene In Acute Cholestasis, Mehmet Tokaç, Sevtap Aydin, Gökçe Taner, Alper Bi̇lal Özkardeş, Mi̇ne Yavuz Taşlipinar, Mehmet Doğan, Hali̇t Zi̇ya Dündar, Mehmet Kiliç, Ari̇f Ahmet Başaran, Ayşe Nurşen Başaran

Turkish Journal of Medical Sciences

Background/aim: Lycopene, which is suggested to be a potent antioxidant, may play a protective role in diseases related to oxidative stress. In order to understand the effects of lycopene in the pathogenesis of cholestasis, we investigated the effects of lycopene on oxidative stress parameters and DNA damage induced by experimental biliary obstruction in the liver tissues and the lymphocytes of Wistar albino rats. Materials and methods: The animals were randomized into 3 groups. The sham group was subjected to a sham operation, the BDL group was subjected to bile duct ligation (BDL), and the BDL+L group was subjected to BDL …

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The Risk Of Tumor Cell Dissemination In Mediastinoscopy: A Cytological Study, Yasemi̇n Bi̇lgi̇n Büyükkarabacak, Ayşen Taslak Şengül, Bi̇lge Can Meydan, Burçi̇n Çeli̇k, Mehmet Gökhan Pi̇rzi̇renli̇, Selçuk Gürz, Zeynep Peli̇n Sürücü, Ahmet Başoğlu Jan 2015

The Risk Of Tumor Cell Dissemination In Mediastinoscopy: A Cytological Study, Yasemi̇n Bi̇lgi̇n Büyükkarabacak, Ayşen Taslak Şengül, Bi̇lge Can Meydan, Burçi̇n Çeli̇k, Mehmet Gökhan Pi̇rzi̇renli̇, Selçuk Gürz, Zeynep Peli̇n Sürücü, Ahmet Başoğlu

Turkish Journal of Medical Sciences

Background/aim: Mediastinoscopy is an invasive procedure that is used in the diagnosis of mediastinal diseases and in staging lung cancer. Tumor cell seeding during mediastinoscopy along the mediastinum and the incision line is a very rare complication. This study aimed to test the safety of mediastinoscopy in terms of tumor seeding by cytological evaluation of mediastinal lavage samples taken before and after biopsy. Materials and methods: The patients who underwent mediastinoscopy in our hospital between 2011 and 2014 were studied prospectively. Seventy-three patients with a diagnosis of lung or mediastinal malignancy were included in the study. All patients underwent classical …

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Does Atraucan Cause More Postdural Puncture Backache?, Ruslan Abdullayev, Ömer Burak Küçükebe, Bülent Çeli̇k, Ni̇hal Ki̇rman, Hami̇t Si̇nan Hati̇poğlu, Fi̇li̇z Akaltun Hati̇poğlu Jan 2015

Does Atraucan Cause More Postdural Puncture Backache?, Ruslan Abdullayev, Ömer Burak Küçükebe, Bülent Çeli̇k, Ni̇hal Ki̇rman, Hami̇t Si̇nan Hati̇poğlu, Fi̇li̇z Akaltun Hati̇poğlu

Turkish Journal of Medical Sciences

Background/aim: Postdural puncture backache (PDPB) is the most frequent complaint after spinal anesthesia. In the literature its importance is generally overshadowed by postdural puncture headache. We studied two different kinds of spinal anesthesia needles to compare their technical handling capacities and incidences of PDPB. Materials and methods: Data of 256 pregnant female patients undergoing cesarean delivery under spinal anesthesia were collected for the study. Patients were divided into two groups as Group A (n = 109) and Group Q (n = 147) according to the spinal needle used for spinal anesthesia (i.e. 26-gauge atraumatic and 26-gauge Quincke needles, respectively). Backache …

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Acute Tuberculosis In The Intensive Care Unit, Kazim Rollas, Ati̇la Kara, Nazmi̇ye Ebru Ortaç Ersoy, Kezban Özmen Süner, Mehmet Nezi̇r Güllü, Serpi̇l Öcal, Arzu Topeli̇ Jan 2015

Acute Tuberculosis In The Intensive Care Unit, Kazim Rollas, Ati̇la Kara, Nazmi̇ye Ebru Ortaç Ersoy, Kezban Özmen Süner, Mehmet Nezi̇r Güllü, Serpi̇l Öcal, Arzu Topeli̇

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to determine mortality rates and to evaluate clinical features of patients with active tuberculosis (TB) requiring intensive care unit (ICU) admission. Materials and methods: The medical records of active TB patients requiring ICU admission were retrospectively reviewed over a 5-year period. Results: Sixteen patients with active TB admitted to the ICU were included in the study. Seven (43.8%) patients died in the ICU. The cause of mortality was septic shock in 5 patients and respiratory failure in 2 patients. The Acute Physiology and Chronic Health Evaluation II (APACHE II) and Sequential Organ Failure …

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Healthy Subjects' Knowledge Of Surgical Complications: A Hospital-Based Survey, Abdussamed Yalçin, Ersi̇n Gürkan Dumlu, Mehmet Tokaç, Ömer Parlak, Levent Öztürk, Mehmet Kiliç Jan 2015

Healthy Subjects' Knowledge Of Surgical Complications: A Hospital-Based Survey, Abdussamed Yalçin, Ersi̇n Gürkan Dumlu, Mehmet Tokaç, Ömer Parlak, Levent Öztürk, Mehmet Kiliç

Turkish Journal of Medical Sciences

Background/aim: There is an ongoing debate about how much a patient should know about serious or frequently occurring risks of their surgery. In this study, we evaluated healthy subjects' perspectives on knowledge of serious surgical complications. Materials and methods: Three hundred and thirty healthy subjects (151 women, 179 men; mean age: 43.6 ± 17.3 years) were surveyed with the study questionnaire. Social profile, surgical history of the healthy subjects, and presence of a relative while giving preoperative consent were assessed. Results: Only 23.5% (39/166) of the subjects were informed about all the potential complications of their previous surgical operation and …

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Smoking Cessation And The Effect Of Nicotine Dependence Onrelapse Rate In İzmir, Turkey, Özlem Pekel, Gül Ergör, Türkan Günay, Hakan Baydur, Beri̇l Choussein, Refi̇k Budak, Si̇nem Doğanay Jan 2015

Smoking Cessation And The Effect Of Nicotine Dependence Onrelapse Rate In İzmir, Turkey, Özlem Pekel, Gül Ergör, Türkan Günay, Hakan Baydur, Beri̇l Choussein, Refi̇k Budak, Si̇nem Doğanay

Turkish Journal of Medical Sciences

Background/aim: Smoking is the leading preventable cause of death in the world. There is growing evidence of the need for community-based programs on smoking cessation. The main purpose of this study is to establish the rate of smoking cessation and restarting in 1 year at the Balçova Smoking Cessation Center. Materials and methods: This is a prospective study with a study group of 359 individuals who quit smoking at the Balçova Smoking Cessation Center for at least 4 weeks between October 2009 and April 2010. The outcomes of the study were 1-year cessation rate and relapse rate. Individuals who reported …

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