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Articles 841 - 870 of 11981
Full-Text Articles in Medicine and Health Sciences
Using A New Evidence-Based Health Workforce Innovation Research Framework To Compare Innovations In Community Health Center And Other Ambulatory Care Settings, Leah E. Masselink, Patricia Pittman, Claire Houterman
Using A New Evidence-Based Health Workforce Innovation Research Framework To Compare Innovations In Community Health Center And Other Ambulatory Care Settings, Leah E. Masselink, Patricia Pittman, Claire Houterman
Health Workforce Research Center Publications
In the United States, changing demographics, rising costs, and the impact of new regulations and payment models arising from the Affordable Care Act have placed unprecedented pressures on healthcare providers to increase access to care, improve quality and to control costs. To meet these challenges, some providers are forming accountable care organizations (ACOs) while others are pursuing medical homes or other novel payment and care delivery models designed to help meet these challenges. Within established organizations such as federally funded community health centers (CHCs), healthcare leaders are exercising significant latitude in developing innovative solutions for meeting their patients’ needs more …
What's Happening: November 30, 2015, Maine Medical Center
What's Happening: November 30, 2015, Maine Medical Center
What's Happening
No abstract provided.
Pesticide Exposure, Behavior Of Farmer, And Activity Of Cholinesterase Enzyme In Blood Of Fertile Women Farmers, Deni Abdul Rahman, Zakianis Zakianis, Laila Fitria
Pesticide Exposure, Behavior Of Farmer, And Activity Of Cholinesterase Enzyme In Blood Of Fertile Women Farmers, Deni Abdul Rahman, Zakianis Zakianis, Laila Fitria
Kesmas
Petani perempuan usia subur berisiko mengalami penurunan aktivitas kolinesterase akibat pajanan pestisida. Penelitian ini bertujuan untuk menganalisis hubungan antara pajanan pestisida dan perilaku pemajan terhadap aktivitas kolinesterase petani perempuan usia subur di Desa Kedunguter. Penelitian ini menggunakan desain potong lintang pada 94 petani perempuan usia subur tahun 2015. Pengumpulan data dilakukan secara observasi, wawancara, dan uji kolinesterase. Analisis data menggunakan uji kai kuadrat dan hasil analisis menunjukkan hubungan signifikan antara jenis pestisida, waktu kerja, penggunaan sarung tangan, perilaku mencuci tangan terhadap aktivitas kolinesterase petani perempuan usia subur. Hasil analisis pada penelitian ini menunjukkan bahwa variabel waktu kerja memiliki nilai odds …
The Use Of Earthworms And Household Organic Waste Composting Length Of Time, Abdul Khair, Lucky Herawati, Noraida Noraida, Munawar Raharja
The Use Of Earthworms And Household Organic Waste Composting Length Of Time, Abdul Khair, Lucky Herawati, Noraida Noraida, Munawar Raharja
Kesmas
Pengomposan dengan cacing tanah merupakan proses pembuatan kompos dengan melibatkan organisme makro cacing tanah. Kerja sama antara cacing tanah dengan mikroorganisme dapat memberi dampak pada proses penguraian yang dilakukan oleh mikroorganisme tersebut dibantu dengan keberadaan cacing tanah. Oleh karena bahan-bahan yang akan diurai oleh mikroorganisme telah diurai lebih dahulu oleh cacing, maka kerja mikroorganisme lebih efektif dan lebih cepat. Penelitian ini bertujuan untuk mengetahui pengaruh penggunaan cacing tanah terhadap lama waktu pengomposan sampah organik dari rumah tangga dengan menggunakan desain penelitian eksperimen. Objek penelitian adalah seluruh sampah organik dari rumah tangga yang diambil secara acak pada satu rumah tangga. Variabel …
Riwayat Berat Badan Lahir Dengan Kejadian Stunting Pada Anak Usia Bawah Dua Tahun, Atikah Rahayu, Fahrini Yulidasari, Andini Octaviana Putri, Fauzie Rahman
Riwayat Berat Badan Lahir Dengan Kejadian Stunting Pada Anak Usia Bawah Dua Tahun, Atikah Rahayu, Fahrini Yulidasari, Andini Octaviana Putri, Fauzie Rahman
Kesmas
Kabupaten Hulu Sungai Utara masih dihadapkan dengan permasalahan gizi pada anak bawah dua tahun (baduta). Salah satu masalah gizi hingga saat ini adalah stunting. Anak dengan riwayat berat badan lahir rendah (BBLR) merupakan salah satu faktor yang potensial memengaruhi pertumbuhan anak. Penelitian ini bertujuan untuk mengkaji risiko riwayat berat badan lahir dengan kejadian stunting pada anak baduta. Desain penelitian adalah potong lintang. Populasi penelitian ini merupakan ibu-ibu yang memiliki anak baduta dan besar sampel sejumlah 117 terdiri dari anak baduta. Pelaksanaan penelitian dilakukan selama tiga bulan pada bulan September – November 2014. Kategori BBLR jika riwayat berat badan lahir < 2.500 gram. Analisis data bivariat menggunakan uji kai kuadrat dan data multivariat menggunakan uji regresi logistik. Hasil analisis bivariat menunjukkan bahwa terdapat hubungan yang signifikan antara riwayat status BBLR (nilai p = 0,015) dengan stunting pada anak baduta. Berdasarkan hasil analisis multivariat, diperoleh bahwa BBLR merupakan faktor risiko yang paling dominan berhubungan dengan kejadian stunting. Anak dengan BBLR memiliki risiko 5,87 kali untuk mengalami stunting. Riwayat BBLR memiliki peranan penting dalam kejadian stunting anak baduta di wilayah Puskesmas Sungai Karias, Hulu Sungai Utara. North Hulu Sungai District is still facing nutrition problems among children under two years old. One of nutrition problems up to now is stunting. Child with low birthweight (LBW) record is one of potential factors influencing the growth of a child. This study aimed to assess any risk of LBW records with stunting incidence among children under two years old. This study used cross-sectional design. The population was mothers having children under two years old and samples amounted to 117 consisted of children under two years old. This study was conducted within three months on September – November 2014. Category of LBW was if birth weight records < 2,500 gram. Bivariate data analysis used chi-square test and multivariate data analysis used logistic regression test. The result of bivariate analysis showed a significant relation between LBW status records (p value = 0.015) with stunting incidence among children under two years old. Based on the result of multivariate analysis, LBW was the most dominating risk factor related to stunting incidence. Children with LBW had 5.87 times risk of suffering from stunting. LBW records take an important role in stunting incidence among children under two years old around Sungai Karias Primary Health Care area in North Hulu Sungai.
Penemuan Kasus Infeksi Kusta Subklinis Pada Anak Melalui Deteksi Kadar Antibodi (Igm) Anti Pgl-1, Arif Sujagat, Fardhiasih Dwi Astuti, Eva Muslimawati Saputri, Annisa Sani, Agil Dwi Prasetya
Penemuan Kasus Infeksi Kusta Subklinis Pada Anak Melalui Deteksi Kadar Antibodi (Igm) Anti Pgl-1, Arif Sujagat, Fardhiasih Dwi Astuti, Eva Muslimawati Saputri, Annisa Sani, Agil Dwi Prasetya
Kesmas
]Kusta merupakan penyakit menular kronis yang disebabkan Mycobacterium leprae. Indonesia menempati peringkat ketiga penyumbang kasus kusta terbanyak di dunia pada tahun 2012 – 2014. Kota Surabaya merupakan daerah endemis kusta. Penelitian ini bertujuan untuk deteksi dini kusta subklinis berdasarkan pengukuran kadar antibodi (IgM) anti PGL-1 dan mengetahui faktor-faktor yang berhubungan dengan kusta subklinis pada anak di Kota Surabaya. Penelitian analitik menggunakan desain potong lintang pada bulan April - Mei 2015. Populasi dilakukan penelitian adalah keluarga yang memiliki anggota penderita kusta. Sampel dipilih dengan teknik simple random sampling dan sebanyak 30 kepala keluarga terpilih melalui rapid school and village survey pada …
Pre-Eklampsia Berat Dan Kematian Ibu, Nova Muhani, Besral Besral
Pre-Eklampsia Berat Dan Kematian Ibu, Nova Muhani, Besral Besral
Kesmas
Pre-eklampsia berat, salah satu penyebab utama kematian ibu di Indonesia dan di RSUD Dr. H. Abdul Moeloek Lampung, merupakan penyebab kematian ibu nomor satu (47,25%). Penelitian ini bertujuan untuk mengetahui hubungan prediktor pre-eklampsi berat (PEB) yang dinilai dari tekanan darah sistolik, tekanan darah diastolik, proteiunuria, eklampsia, sindrom hemolysis, elevated liver enzymes, low platelets count (HELLP) dengan kematian ibu di RSUD Dr. H. Abdul Moeloek. Penelitian ini menggunakan desain kasus kontrol dengan jumlah sampel 60 kasus dan 120 kontrol. Data diolah dari rekam medis rumah sakit selama periode lima tahun (2010 – 2014). Hasil penelitian ini memperlihatkan bahwa sindrom HELLP memiliki …
Peran Tenaga Kesehatan Dan Keluarga Dalam Kehamilan Usia Remaja, Mery Ramadani, Dien Gusta Anggraini Nursal, Livia Ramli
Peran Tenaga Kesehatan Dan Keluarga Dalam Kehamilan Usia Remaja, Mery Ramadani, Dien Gusta Anggraini Nursal, Livia Ramli
Kesmas
Sebanyak 10,3% kematian tidak langsung pada ibu disebabkan kehamilan usia remaja (< 20 tahun). Di Kabupaten Tanah Datar, masih terjadi peningkatan kehamilan usia remaja dalam tiga tahun terakhir. Penelitian ini bertujuan untuk mengetahui peran tenaga kesehatan, dukungan keluarga, dan pengetahuan remaja dengan kehamilan usia remaja di wilayah kerja Puskesmas Singgalang, Kabupaten Tanah Datar tahun 2014. Penelitian dilaksanakan pada bulan Mei – Juni 2014 menggunakan desain potong lintang. Populasi adalah seluruh remaja putri berusia < 20 tahun yang telah menikah berjumlah 215 orang. Sampel berjumlah 68 orang dan pengambilan sampel dilakukan secara proporsional di delapan jorong/desa. Data dikumpulkan melalui wawancara menggunakan kuesioner. Kemudian, analisis bivariat dilakukan dengan uji kai kuadrat dan analisis multivariat dengan uji regresi logistik ganda. Hasil penelitian mendapatkan sebanyak 55,9% responden hamil di usia remaja. Sebanyak 52,9% responden kurang merasakan peran dari tenaga kesehatan, 66,2% kurang mendapat dukungan keluarga, dan 58,8% memiliki pengetahuan rendah. Didapatkan hubungan peran tenaga kesehatan (nilai p = 0,032), dukungan keluarga (nilai p = 0,025), dan tingkat pengetahuan (nilai p = 0,002) dengan kehamilan usia remaja. Dapat disimpulkan bahwa tenaga kesehatan, keluarga dan tingkat pengetahuan berperan dalam kehamilan remaja. Tenaga kesehatan perlu memberikan penyuluhan mengenai risiko kehamilan remaja kepada remaja serta keluarga. Worth 10.3% of indirect maternal death is due to teenage pregnancy (< 20 years old). In Tanah Datar District, the increase of teenage pregnancy has occured in the last three years. This study aimed to determine health worker's role, family's support and teenagers' knowledge with teenage pregnancy in work area of Singgalang Primary Health Care, Tanah Datar District in 2014. This study was conducted on May – June 2014 using cross-sectional design. Population was 215 married teenage girls < 20 years old. A total of sample was 68 selected proportionally in eight villages. Data were collected through interview using questionnaire. Then bivariate analysis was conducted using chi-square test and multivariate analysis using multiple logistic regression test. Results of study found 55.9% of respondents were pregnant in teen age. Respondents worth 52.9% got less health worker’s role, 66.2% got less family’s support and 58.8% had low level of knowledge. There was a relation found between health worker’s role (p value = 0.032), family’s support (p value = 0.025) and knowledge level (p value = 0.002) with teenage pregnancy. In conclusion, health workers, family and knowledge level play a role in teenage pregnancy. Health workers need to provide counseling concerning teenage pregnancy risks for both teenagers and families.
Pengaruh Musik Keroncong Selama Pelaksanaan Kangaroo Mother Care Terhadap Respons Fisiologis Dan Lama Rawat Bayi Dengan Berat Badan Lahir Rendah, Anita Rahmawati, Endah Marianingsih Theresia, Yuliasti Eka Purnamaningrum
Pengaruh Musik Keroncong Selama Pelaksanaan Kangaroo Mother Care Terhadap Respons Fisiologis Dan Lama Rawat Bayi Dengan Berat Badan Lahir Rendah, Anita Rahmawati, Endah Marianingsih Theresia, Yuliasti Eka Purnamaningrum
Kesmas
Kangaroo mother care (KMC) merupakan metode merawat bayi berat badan lahir rendah (BBLR). Beberapa intervensi perawatan di neonatal intensive care unit seperti pijat bayi, KMC, dan mendengarkan musik bermanfaat untuk pertumbuhan bayi berupa respons fisiologis BBLR dan mengurangi lama rawat. Penelitian ini bertujuan untuk mengetahui manfaat musik keroncong terhadap respons BBLR selama KMC dan lama rawat. Rancangan penelitian adalah quasi eksperimental dengan pretest dan posttest dengan desain grup kontrol. Pada Juli - September 2014 populasi penelitian adalah ibu dan bayi BBLR yang melaksanakan KMC. Pengambilan sampel dengan purposive sampling sebanyak 60 bayi. Kriteria inklusi bayi BBLR yang ditetapkan adalah berat …
Aprosodia Therapy: The Impact On Affective Prosody In A Child With High Functioning Autism, Andria Hutchison
Aprosodia Therapy: The Impact On Affective Prosody In A Child With High Functioning Autism, Andria Hutchison
Student Theses and Dissertations
Aprosodia, a disorder that results from damage to the right hemisphere of the brain, affects a person’s ability to comprehend and/or express emotion through changes in voice, or prosody. A common characteristic in children with High Functioning Autism (HFA) is a flat, monotonous voice that affects social reciprocity and communicative competence. The purpose of the current study was to evaluate the effects of the imitative approach, established for adults with aprosodia due to right hemisphere damage, on the affective prosodic skills in a child with HFA. A within subject research design was selected, and one participant received the imitative intervention …
Improved Sensitivity To Fluorescence For Cancer Detection In Wide-Field Image-Guided Neurosurgery, Michael Jermyn, Yoann Gosselin, Pablo A. Valdes, Mira Sibai, Kolbein Kolste
Improved Sensitivity To Fluorescence For Cancer Detection In Wide-Field Image-Guided Neurosurgery, Michael Jermyn, Yoann Gosselin, Pablo A. Valdes, Mira Sibai, Kolbein Kolste
Dartmouth Scholarship
In glioma surgery, Protoporphyrin IX (PpIX) fluorescence may identify residual tumor that could be resected while minimizing damage to normal brain. We demonstrate that improved sensitivity for wide-field spectroscopic fluorescence imaging is achieved with minimal disruption to the neurosurgical workflow using an electron-multiplying charge-coupled device (EMCCD) relative to a state-of-the-art CMOS system. In phantom experiments the EMCCD system can detect at least two orders-of-magnitude lower PpIX. Ex vivo tissue imaging on a rat glioma model demonstrates improved fluorescence contrast compared with neurosurgical fluorescence microscope technology, and the fluorescence detection is confirmed with measurements from a clinically-validated spectroscopic probe. Greater PpIX …
Disability Prevention Programs For Older People: Factors Associated With Medical And Nursing Care Costs, Takaaki Ikeda, Susumu Yanagawa, Kenichi Murakami, Toshiyuki Inoue, Takamasa Tsurumi
Disability Prevention Programs For Older People: Factors Associated With Medical And Nursing Care Costs, Takaaki Ikeda, Susumu Yanagawa, Kenichi Murakami, Toshiyuki Inoue, Takamasa Tsurumi
Kesmas
Penelitian ini bertujuan untuk mengklarifikasi faktor-faktor yang terkait dengan biaya medis dan perawatan lanjut usia (lansia) yang tinggal di panti sosial serta menyarankan program pencegahan disabilitas yang efektif. Total partisipan dalam penelitian ini adalah 83 orang (29 laki-laki dan 54 perempuan; usia rata-rata 81,2 ± 6,3 tahun) pada 1 November – 28 Desember 2014. Penelitian ini membandingkan biaya medis dan perawatan rata-rata per bulan dengan rata-rata nasional bagi yang berusia ≥ 65 tahun. Uji regresi logistik dilakukan untuk memeriksa keterkaitannya dengan biaya medis dan perawatan. Mereka yang pergi ke luar rumah ≥ 3 kali seminggu tiga kali lebih kecil kemungkinannya …
Dancing Through Life: Molecular Dynamics Simulations And Network-Centric Modeling Of Allosteric Mechanisms In Hsp70 And Hsp110 Chaperone Proteins, Gabrielle Stetz, Gennady M. Verkhivker
Dancing Through Life: Molecular Dynamics Simulations And Network-Centric Modeling Of Allosteric Mechanisms In Hsp70 And Hsp110 Chaperone Proteins, Gabrielle Stetz, Gennady M. Verkhivker
Mathematics, Physics, and Computer Science Faculty Articles and Research
Hsp70 and Hsp110 chaperones play an important role in regulating cellular processes that involve protein folding and stabilization, which are essential for the integrity of signaling networks. Although many aspects of allosteric regulatory mechanisms in Hsp70 and Hsp110 chaperones have been extensively studied and significantly advanced in recent experimental studies, the atomistic picture of signal propagation and energetics of dynamics-based communication still remain unresolved. In this work, we have combined molecular dynamics simulations and protein stability analysis of the chaperone structures with the network modeling of residue interaction networks to characterize molecular determinants of allosteric mechanisms. We have shown that …
Medical School Watercooler Newsletter - November 29, 2015, Lindsey Lyle
Medical School Watercooler Newsletter - November 29, 2015, Lindsey Lyle
Watercooler Newsletter
This is the November 29, 2015 edition of the Frederick P. Whiddon College of Medicine's Newsletter - Watercooler.
Contents Include:
USA PsychSIGN Hosts Mental Health Outreach Event
Dr. Molokhia Presents at International Conference
Dr. Craig Sherman Recognized for Customer Service
December Med School Cafe - 'Upper Extremity Arthritis Management Tips
Diabetes Training For Community Health Workers, Judith Aponte
Diabetes Training For Community Health Workers, Judith Aponte
Publications and Research
Background: A 2.5-month diabetes education training for community health workers (CHWs) was developed, implemented, and evaluated.
Methods: Training methods used included case studies, role-playing, and lectures. Exams were used throughout the training for its evaluation. Teaching was delivered by different ways: a one day American Diabetes Association (ADA) course; a five day Diabetes Self-Management Program (DSMP); Conversation Maps; and a series of seven National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) diabetes education booklets.
Results: Qualitative and quantitative evaluative methods were used during and after the training. The CHWs' diabetes knowledge was evaluated by a pre- and post-test …
Illicit Drugs: Should They Be Legalized? Can Technology And Regulation Make Them Safer?, Max Lee Ketcham Iii
Illicit Drugs: Should They Be Legalized? Can Technology And Regulation Make Them Safer?, Max Lee Ketcham Iii
University Honors Program
For many years America has been the leading force in substance prohibition. Many countries blindly follow the USA in an attempt to earn their respect. As a result, very few countries actually know what uses these illicit substances have; before it ever reached the hands of the right people, the wrong people take it, use it incorrectly, and leave a bad name on that substance forever. If people could slander a substance, America would end up being found the main conspirator in the slanderous lies and misconceptions! This study has been done in an attempt to clear the name of …
Pursuing Legislative Authority For Clinical Social Workers To Provide Private Independent Mental Health Services: What Is The Status And What Are The Issues?, Caroline Blower
University Honors Program
The scope of clinical social work practice differs among the various US states as defined by legislative codes. Understanding these differences is challenging because legislative codes are difficult to read, sometimes requires advanced knowledge to interpret, or do not provide the sufficient breadth and/or depth of information to enable a full understanding of practice limits. The study utilized an electronic survey and asked social workers throughout the US five questions about providing private independent mental health services. These questions addressed the ability of licensed clinical social workers (LCSWs) to (1) provide diagnosis, (2) create treatment plans, (3) bill third party …
The Men And Women Merely Players: Can Dramatherapy Can Help Those Who Need It Most?, Olivia Underwood
The Men And Women Merely Players: Can Dramatherapy Can Help Those Who Need It Most?, Olivia Underwood
University Honors Program
Within the following work, we will discover the history, applications, and effectiveness of Dramatherapy, also called drama therapy. By looking at the origins of the ideas of both Psychodrama and Dramatherapy, we can see how far it has come and where it still needs to go. This information came from texts books, memoirs, and various articles. After that we will find how the efforts of Dramatherapists have paid off. By looking at specific case studies from the Americas and abroad, we can see the positive effects that using the traditions of theater as therapy. Across the board we see positive …
Concussions Related To Football, Jerry Stephen
Concussions Related To Football, Jerry Stephen
University Honors Program
Concussions are a major problem in football. They cause short and long term problems. Much is known about the causes of concussions in football, little is yet known about how to truly really decrease the amount of concussions and the effects a concussion really has on an individual, I propose to look at efforts being put in remaking helmets, physiological effects on the brain, and the long term behavioral and emotional effects of concussions. There is an ongoing research to solve the concussion in football. Scientists are learning about the physiological effects on the brain and the long term emotion …
The Health Benefits Of The Mediterranean Diet, Kathryn Cleek
The Health Benefits Of The Mediterranean Diet, Kathryn Cleek
University Honors Program
Introduction This thesis is over the health benefits of the Mediterranean diet, what causes these increase in health benefits. In the introduction of this paper I discuss what the Mediterranean diet is, the history of the Mediterranean diet, who first demonstrated the diet, the physical activity differences in America and Europe, the portion size differences and the Ten Commandments of the diet. Each component of diet is important for understand how the diet works when comparing it to the health of those who demonstrate the diet. Main Body The main body is composed of what I used to find my …
Changes In The Ideal Body Type, Jessica L. Hoffman
Changes In The Ideal Body Type, Jessica L. Hoffman
University Honors Program
The human body comes in all shapes and sizes. Each different body shape allows onlookers to evaluate at least some aspects of the subject’s lifestyle and priorities. All eras choose a body type that they exalt above the rest. The goal of this research is to evaluate the considered ideal body type from three different eras in order to better understand these time periods and their values. A compilation of books and journal articles were used from the Cunningham Memorial Library Database, the library itself, and other personal libraries to better understand this topic. The most pertinent question was what …
Issues Within Nursing Facilities Involving Quality Of Care For The Elderly, Kendal Fluhr
Issues Within Nursing Facilities Involving Quality Of Care For The Elderly, Kendal Fluhr
University Honors Program
The elderly population in the U.S. is growing each and every year. As this population grows, so does the number of senior citizens in need of constant care. Many are put into nursing homes instead of staying with family or receiving in-home care. The issue with this is that far too many nursing facilities do not give high quality care to residents. The goal of this study was to investigate what concerns are common at nursing homes and what can be done to resolve these problems. Based on research studies, articles, statistics, and informational websites, it was found that some …
The Importance Of Being Proactive: Suicide Clusters, Prevention Programs, And Postvention Methods In The High School Setting, Lindsay Farmer
The Importance Of Being Proactive: Suicide Clusters, Prevention Programs, And Postvention Methods In The High School Setting, Lindsay Farmer
University Honors Program
The purpose of this paper is to explain the phenomenon of suicide clustering and suicide contagion in relation to teenagers and the education system and to provide detailed recommendations for both the prevention and postvention of youth suicide in the school system. Due to the prevalence of mental health issues in teenagers, especially depression, it is important for educators to be aware of the risks of youth suicide attempts and completion, as well as the inherent dangers of clustering that may occur. The phenomenon of suicide clustering will be explained, including the methods by which clustering occurs, as well as …
Recurrent Hepatocellular Carcinoma In Patient With Crohn’S Disease: Incidental Or Expected Outcome Of Azathioprine?, Youssef Botros, Mary Mathews, Hiren Patel, Nihar Shah Md, Walid Baddoura, Andrew De La Torre
Recurrent Hepatocellular Carcinoma In Patient With Crohn’S Disease: Incidental Or Expected Outcome Of Azathioprine?, Youssef Botros, Mary Mathews, Hiren Patel, Nihar Shah Md, Walid Baddoura, Andrew De La Torre
Gastroenterology
Hepatocellular carcinoma (HCC) usually occurs in patients with underlying risk factors such as liver cirrhosis and chronic hepatitis B. Although patients with Crohn's disease (CD) are at an increased risk to develop malignancies such as colon cancer, the incidence of HCC in this population is extremely rare. We report a case of 62-year-old male with long history of CD treated with azathioprine (AZA) and aminosalicylic acid (ASA) who was incidentally diagnosed with HCC, for which left hepatectomy was done. Four years later during routine follow-up, patient had another hepatic lesion and underwent resection of the mass. The mechanism of occurrence …
Recurrent Hepatocellular Carcinoma In Patient With Crohn's Disease: Incidental Or Expected Outcome Of Azathioprine?, Youssef Botros, Mary Mathews, Hiren Patel, Nihar Shah Md, Walid Baddoura, Andrew De La Torre
Recurrent Hepatocellular Carcinoma In Patient With Crohn's Disease: Incidental Or Expected Outcome Of Azathioprine?, Youssef Botros, Mary Mathews, Hiren Patel, Nihar Shah Md, Walid Baddoura, Andrew De La Torre
Gastroenterology
Hepatocellular carcinoma (HCC) usually occurs in patients with underlying risk factors such as liver cirrhosis and chronic hepatitis B. Although patients with Crohn’s disease (CD) are at an increased risk to develop malignancies such as colon cancer, the incidence of HCC in this population is extremely rare. We report a case of 62-year-old male with long history of CD treated with azathioprine (AZA) and aminosalicylic acid (ASA) who was incidentally diagnosed with HCC, for which left hepatectomy was done. Four years later during routine follow-up, patient had another hepatic lesion and underwent resection of the mass. The mechanism of occurrence …
Allogeneic Autophagosome-Enriched Composition For The Treatment Of Disease, Traci Hilton, Sandra Aung, Rieneke Van De Ven, Christopher Paustian, Tarsem Moudgil, Christopher Dubay, Christopher Twitty, Hong-Ming Hu, Bernard A Fox
Allogeneic Autophagosome-Enriched Composition For The Treatment Of Disease, Traci Hilton, Sandra Aung, Rieneke Van De Ven, Christopher Paustian, Tarsem Moudgil, Christopher Dubay, Christopher Twitty, Hong-Ming Hu, Bernard A Fox
Technology Transfer - Patents
A method is presented for screening cells that produce allogeneic autophagosome enriched compositions able to induce expression of a selective marker on a subpopulation of peripheral blood mononuclear cells, the method comprising contacting a cell with a proteasome inhibitor, contacting the cell with a lysosome inhibitor, harvesting the resulting autophagosomes, determining a molecular signature of the harvested autophagosomes, and selecting cells that divert one or more Toll-like receptor agonist and/or one or more molecular chaperones to the harvested autophagosomes. By screening for cells that divert one or more Toll-like receptor agonist and/or one or more molecular chaperones to the harvested …
“Whatdunit?” Developmental Changes In Children's Syntactically Based Sentence Interpretation Abilities And Sensitivity To Word Order, James W. Montgomery, Julia L. Evans, Ronald B. Gillam, Alexander V. Sergeev, Mianisha C. Finney
“Whatdunit?” Developmental Changes In Children's Syntactically Based Sentence Interpretation Abilities And Sensitivity To Word Order, James W. Montgomery, Julia L. Evans, Ronald B. Gillam, Alexander V. Sergeev, Mianisha C. Finney
Communicative Disorders and Deaf Education Faculty Publications
Aim 1 of this study was to examine the developmental changes in typically developing English-speaking children’s syntactically-based sentence interpretation abilities and sensitivity to word order. Aim 2 was to determine the psychometric standing of the novel sentence interpretation task developed for this study, as we wish to use it later with children with Specific Language Impairment (SLI). Children listened to semantically implausible sentences in which noun animacy and the natural affordance between the nouns were removed, thus controlling for event probability. Using this novel “whatdunit?” agent selection task, 256 children 7-11 years listened to two structures with canonical word order …
Editorial: Leading People - Managing Organizations: Contemporary Public Health Leadership, James W. Holsinger Jr., Erik L. Carlton, Emmanuel D. Jadhav
Editorial: Leading People - Managing Organizations: Contemporary Public Health Leadership, James W. Holsinger Jr., Erik L. Carlton, Emmanuel D. Jadhav
Preventive Medicine and Environmental Health Faculty Publications
Effectively leading people engaged in the practice of public health has never been more critical than in the early years of the twenty-first century. Likewise, effectively managing the organizations in which these individuals practice the various professional disciplines of public health has become increasing important and difficult. Taken together, leading the people and managing public health organizations requires well educated and appropriately trained public health leaders and managers. Although leadership is often viewed as one of the key attributes of management, not every great manager will be a great leader and vice versa. While some leaders may be born with …
Patricia Maro Dehart, Patricia Maro Dehart, Kelsey Duinkerken
Patricia Maro Dehart, Patricia Maro Dehart, Kelsey Duinkerken
Jefferson Nursing Oral Histories
Patricia Maro DeHart first became interested in nursing in high school when she first volunteered, and later worked, as a nurses’ aide in a local nursing home. She decided to attend Jefferson’s Diploma Nursing program and graduated in 1977. After starting her career in medical surgery at West Jersey Hospital she then worked as an OB-GYN nurse at Thomas Jefferson University Hospital for eleven years. As her career progressed she moved to Bristol-Myers Squibb, where she held a number of varied positions that allowed her to combine both her degrees in nursing and business, including as account executive and government …
Dopaminergic Modulation Of Medial Prefrontal Cortex Deactivation In Parkinson Depression, Anders H. Andersen, Charles D. Smith, John T. Slevin, Richard J. Kryscio, Catherine A. Martin, Frederick A. Schmitt, Lee X. Blonder
Dopaminergic Modulation Of Medial Prefrontal Cortex Deactivation In Parkinson Depression, Anders H. Andersen, Charles D. Smith, John T. Slevin, Richard J. Kryscio, Catherine A. Martin, Frederick A. Schmitt, Lee X. Blonder
Neuroscience Faculty Publications
Parkinson's disease (PD) is associated with emotional abnormalities. Dopaminergic medications ameliorate Parkinsonian motor symptoms, but less is known regarding the impact of dopaminergic agents on affective processing, particularly in depressed PD (dPD) patients. The aim of this study was to examine the effects of dopaminergic pharmacotherapy on brain activation to emotional stimuli in depressed versus nondepressed Parkinson disease (ndPD) patients. Participants included 18 ndPD patients (11 men, 7 women) and 10 dPD patients (7 men, 3 women). Patients viewed photographs of emotional faces during functional MRI. Scans were performed while the patient was taking anti-Parkinson medication and the day after …