Medicine and Health Sciences Commons^™

Understanding Phylogenies: Constructing And Interpreting Phylogenetic Trees, Joseph L. Staton

Journal of the South Carolina Academy of Science

Interpretation of phylogenetic trees is fundamental in understanding the relationships between organisms, their traits or characteristics, their ecology and even their genomic and developmental biology. As trees appear more often in basic texts, many students, and even their teachers, clearly understand little of how they are constructed and even less about what can be inferred from them about the history of the representatives analyzed. Not only are these trees a source of confusion on what they do tell us, often non-specialists infer things wrongly or, worse, others misuse them in an attempt to negate the validity of evolutionary theory. In …

The Rise Of Carbon Nanoscience In South Carolina, Apparao M. Rao

Journal of the South Carolina Academy of Science

No abstract provided.

Scientific Contributions Of The Children’S Physical Activity Research Group, Russell R. Pate, Erica Y. Lau, Jennifer I. Flynn, Samantha M. Mcdonald, Morgan N. Clennin, Michaela A. Schenkelberg

Journal of the South Carolina Academy of Science

No abstract provided.

Qualitative Study Of The United States Marine Corps Wounded Warrior Regiment, Webster F. Nicholson Jr.

Dissertations

Serious health care issues were discovered first at Walter Reed Army Medical Center in 2007 and later at U.S. Department of Veteran Affairs health care organizations in 2014 (Brady, 2012; Cohen, Griffin, & Bronstein, 2014; Wright, 2013). The continued success of the Wounded Warrior Program requires a system that will constantly assess and analyze health care quality from the patient’s experience. From a systems perspective, health care quality encompasses six dimensions, and the study involved examining the dimension and four core concepts of patient-centered care (Institute of Medicine, 2001; Lees, 2011; Wexler, 2002; World Health Organization, 2006). A qualitative, phenomenological …

Medical School Watercooler Newsletter - April 12, 2015, Lindsey Lyle

Watercooler Newsletter

This is the April 12, 2015 edition of the Frederick P. Whiddon College of Medicine's Newsletter - Watercooler.

Contents Include:

USA Medical Student to Graduate with Research Honors

USA Physician Recognized for Customer Service

USA Surgery Hosts Greater Gulf Coast Trauma and Acute Care Surgery Symposium

USA Surgical Oncologist Earns New Board Certification

USA Libraries Book Drive In Progress

The Road To A Happier Health Care System: Lessons From Denmark, Deanna Karam

Annual Undergraduate Conference on Health and Society

The lack of an organized primary care system in the United States not only contributes to high health care costs, but also to decreased access to care, increased fragmentation, and poor health outcomes. The Scandinavian country of Denmark, with its universal health care system and “cozy and snug” lifestyle offers a model for reforming the US health care system. In Denmark, primary care is organized around a gatekeeping system, in which General Practitioners serve as gatekeepers to other medical services, including hospitals and specialists. This system is responsible for Denmark’s well-organized and coordinated primary care system, which largely contributes to …

“Can You Hear Me Now?”: Insurance Coverage For Hearing Benefits In The United States, Reegan Whipple

Annual Undergraduate Conference on Health and Society

Public and private insurance coverage for hearing benefits underscores the gaps in coverage for treating hearing loss in the U.S. The commodification of the hearing benefits sector of healthcare in this country has detrimental consequences for personal health. Using three personal anecdotes to frame the issue, my paper explores the complex worlds of both public and private insurance as well as the implications of each type of insurance for both adults and children. Current regulations and laws for hearing benefits leave many people to suffer financially, physically, and emotionally. After reviewing the current regulations I propose changes to rectify some …

Survival Prediction In High-Grade Gliomas Using Ct Perfusion Imaging., Timothy Pok Chi Yeung, Yong Wang, Wenqing He, Benedetta Urbini, Roberta Gafà, Linda Ulazzi, Slav Yartsev, Glenn Bauman, Ting-Yim Lee, Enrico Fainardi

Medical Biophysics Publications

Patients with high-grade gliomas usually have heterogeneous response to surgery and chemoirradiation. The objectives of this study were (1) to evaluate serial changes in tumor volume and perfusion imaging parameters and (2) to determine the value of these data in predicting overall survival (OS). Twenty-nine patients with World Health Organization grades III and IV gliomas underwent magnetic resonance (MR) and computed tomography (CT) perfusion examinations before surgery, and 1, 3, 6, 9, and 12 months after radiotherapy. Serial measurements of tumor volumes and perfusion parameters were evaluated by receiver operating characteristic analysis, Cox proportional hazards regression, and Kaplan-Meier survival analysis …

14th Annual Undergraduate Student Symposium, Farquhar Honors College

Undergraduate Student Symposium

The Undergraduate Student Symposium, sponsored by the Farquhar College of Arts and Sciences, presents student projects through presentations, papers, and poster displays. The event serves as a “showcase” demonstrating the outstanding scholarship of undergraduate students at NSU. The symposium is open to undergraduate students from all disciplines. Projects cover areas of student scholarship ranging from the experimental and the applied to the computational, theoretical, artistic, and literary. They are taken from class assignments and independent projects. The projects do not have to be complete; presentations can represent any stage in the concept’s evolution, from proposal and literature review to fully …

Wright State University's Celebration Of Research, Scholarship And Creative Activities Book Of Abstracts From Friday, April 10, 2015, Wright State University Office Of Undergraduate Research And Stemm Activities

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

The student abstract booklet is a compilation of abstracts from students' oral and poster presentations at Wright State University's fifth annual Celebration of Research, Scholarship and Creative Activities on April 10, 2015.

No Oasis In The Desert: Identification And Implications Of The Food Desert Around An Urban Ohio Hospital, R. J. Sontag

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

Montgomery County, Ohio’s diabetes prevalence outpaces the nation, and the incidence of adult obesity approaches 1/3. Access to healthy food in the impoverished neighborhood surrounding Dayton’s Good Samaritan Hospital, the site of the Family Medicine residency, is important when educating about health lifestyle. The purpose of this project was to determine whether the area was a food desert and to evaluate the implications of the label.

Attenuation Of Traumatic Brain Injury-Induced Cognitive Impairment In Mice By Targeting Increased Cytokine Levels With A Small Molecule Experimental Therapeutic, Adam D. Bachstetter, Scott J. Webster, Danielle S. Goulding, Jonathan E. Morton, D. Martin Watterson, Linda J. Van Eldik

Sanders-Brown Center on Aging Faculty Publications

BACKGROUND: Evidence from clinical studies and preclinical animal models suggests that proinflammatory cytokine overproduction is a potential driving force for pathology progression in traumatic brain injury (TBI). This raises the possibility that selective targeting of the overactive cytokine response, a component of the neuroinflammation that contributes to neuronal dysfunction, may be a useful therapeutic approach. MW151 is a CNS-penetrant, small molecule experimental therapeutic that selectively restores injury- or disease-induced overproduction of proinflammatory cytokines towards homeostasis. We previously reported that MW151 administered post-injury (p.i.) is efficacious in a closed head injury (CHI) model of diffuse TBI in mice. Here we test …

The Impact Of A Community Garden On A Local Township, Mariah E. Reitz

Undergraduate Distinction Papers

Due to increasing food insecurity and food deserts, community gardens can increase the accessibility for those under-served populations. These community gardens can help with the mental and physical health of the public. The goal of this research is to determine if a community garden will benefit a smaller community like that of a suburban Township and to use these trends to increase community health education and availability, social cohesion, and overall health behaviors and practices. A survey evaluated overall consumption of fruits and vegetables, affordability of healthy foods, and education on the consumption of these foods as well as assessing …

Woodrow Wilson’S Ideological War: American Intervention In Russia, 1918-1920, Shane Hapner

Best Integrated Writing

Shane Hapner analyzes the effects of Woodrow Wilson’s principle of self-determination on American intervention in Russia from 1918-1920 in this essay written for the Integrated Writing course HST 4220: Soviet Union, taught by Dr. Seam Pollock at Wright State University.

Circular Thinking: An Original Analysis Of Lord Of The Flies, John Callon

Best Integrated Writing

John Callon examines traits of circular thinking and imagery in William Golding’s Lord of the Flies in this essay written for the Integrated Writing course ENG 4560: Capstone in Integrated Language Arts Curriculum, taught by Dr. Nancy Mack at Wright State University.

Are The Main Institutional Changes That Created The “Business Man” Still Relevant?, Hayden Joblin

Best Integrated Writing

Hayden Joblin examines the forces driving the evolution of the modern business man and whether those still have relevance in this essay written for the Integrated Writing course EC 3190: Institutional Economics, taught by Dr. Hee Young Shin at Wright State University.

Identifying Genes Involved In Suppression Of Tumor Formation In The Planarian Schmidtea Mediterranea, Erin Dorsten

Best Integrated Writing

Erin Dorsten makes a proposal for a scientific study of experiments to identify genes involved in protecting an organism with negligible senescence from tumor formation in this piece written for the Integrated Writing course BIO 4020: Current Literature: Biology of Regeneration, taught by Labib Rouhana at Wright State University.

The Barb Report, Elizabeth Schoppelrei

Best Integrated Writing

Elizabeth Schoppelrei explores issues of sexuality, kindness, masculinity, discrimination, and respect in this short story written for the Integrated Writing course ENG 4830: Advanced Fiction Writing Seminar, taught by Dr. Erin Flanagan at Wright State University.

How To Recover From The Great Recession And Reduce The Government Debt, Hunter Cregger

Best Integrated Writing

Hunter Cregger proposes how to recover from the Great Recession of the 2000s and reduce government debt in this essay written for the Integrated Writing course EC 2050: Principles of Macroeconomics, taught by Dr. Hee Young Shin at Wright State University.

Inter-Tribal Disunity: An Analysis Of Inter-Tribal Conflict During The Black Hawk War Of 1832, Megan Bailey

Best Integrated Writing

Megan Bailey explores the effects of inter-tribal disunity and conflict on the Black Hawk War of 1832 in this essay written for the Integrated Writing course HST 3000: Introduction to Historical Analysis, taught by Dr. Noeleen McIlvenna at Wright State University.

Effects Of Caffeine And Vitamin E On Wisconsin Fast Plant, Sarah Ferguson

Best Integrated Writing

Sarah Ferguson examines the effects of caffeine and vitamin E on the growth of Wisconsin Fast Plant in this piece written for the Integrated Writing course BIO 3450: Concepts of Biology I for Early and Middle Childhood Education, taught by Mr. Len Kenyon at Wright State University.

Best Integrated Writing 2015 - Complete Edition

Best Integrated Writing

Best Integrated Writing includes excellent student writing from Integrated Writing courses taught at Wright State University. The journal is published annually by the Wright State University Department of English Language and Literatures.

Experiences, Perceived Challenges, And Support Systems Of Early College High School Students, Karen P. Sáenz, Julie P. Combs

Administrative Issues Journal

In this qualitative study, the prior experiences, perceived challenges, and support systems of 17 Grade 12 Hispanic students at an early college high school were explored using the framework of social capital theory. Utilizing Moustakas’s phenomenological design, data were collected using focus group and individuals interviews. Several themes emerged and were related to the conceptual framework of social capital, such as the school environment, support from family and teachers, and the students’ identify and values. Understanding the experiences of the Grade 12 students can provide valuable information for high school and college administrators in an ECHS setting.

Prevalence Of And Risk Factors For Degenerative Mitral Valve Disease In Dogs Attending Primary‐Care Veterinary Practices In England, M. Mattin, A. Boswood, D. B. Church, J. López-Alvarez, P. D. Mcgreevy, D. G. O'Neill, P. C. Thomson, D. C. Brodbelt

Epidemiology Collection

Background

To date, epidemiological studies on degenerative mitral valve disease (DMVD) in dogs have largely reported referral caseloads or been limited to predisposed breeds. Analysis of primary‐care data to identify factors associated with DMVD would help clinicians identify high‐risk individuals and improve understanding.

Objectives

To estimate the prevalence of and identify risk factors for DMVD in dogs attending primary‐care veterinary practices in England.

Animals

Cases were identified within the electronic patient records of 111,967 dogs attending 93 practices. Four hundred and 5 dogs were diagnosed with DMVD (diagnosed cases) and a further 3,557 dogs had a heart murmur (HM) consistent …

One-Step Generation Of Multiple Transgenic Mouse Lines Using An Improved Pronuclear Injection-Based Targeted Transgenesis (I-Pitt)., Masato Ohtsuka, Hiromi Miura, Keiji Mochida, Michiko Hirose, Ayumi Hasegawa, Atsuo Ogura, Ryuta Mizutani, Minoru Kimura, Ayako Isotani, Masahito Ikawa, Masahiro Sato, Channabasavaiah B. Gurumurthy

Journal Articles: Genetics, Cell Biology & Anatomy

BACKGROUND: The pronuclear injection (PI) is the simplest and widely used method to generate transgenic (Tg) mice. Unfortunately, PI-based Tg mice show uncertain transgene expression due to random transgene insertion in the genome, usually with multiple copies. Thus, typically at least three or more Tg lines are produced by injecting over 200 zygotes and the best line/s among them are selected through laborious screening steps. Recently, we developed technologies using Cre-loxP system that allow targeted insertion of single-copy transgene into a predetermined locus through PI. We termed the method as PI-based Targeted Transgenesis (PITT). A similar method using PhiC31-attP/B system …

Surgical Outcomes Of Sequential Versus Concomitant Glaucoma Drainage Implant And Boston Keratoprosthesis Type 1, Varum Patel, Marlene R. Moster, Louis J. Kishfy, Julian Barkan, Tingting Zhan, Irving M. Raber, Brandon D. Ayers, Michael J. Pro, Michael Waisbourd

Wills Eye Hospital Papers

BACKGROUND

The Boston Keratoprosthesis Type 1 (KPro) is a surgical device used in patients who have failed traditional corneal transplant treatment or are poor candidates for it.¹ Candidates for KPro often have advanced anterior segment disease that predisposes them to developing glaucoma.² As a result, these patients may require both a KPro, to treat their corneal pathology, and a glaucoma drainage implant (GDI), to treat their glaucoma. To date, there have been no long-term studies comparing the order of GDI placement with KPro surgery and how it affects surgical outcomes.

Supporting Practices To Adopt Registry-Based Care (Sparc): Protocol For A Randomized Controlled Trial, Rebeccar S. Etz, Rosalind E. Keith, Anna M. Matemick, Karen L. Stein, Roy T. Sabo, Melissa S. Hayes, Purvi Sevak, John Holland, Jesse C. Crosson

Publications and Research

Background: Diabetes is predicted to increase in incidence by 42% from 1995 to 2025. Although most adults with diabetes seek care from primary care practices, adherence to treatment guidelines in these settings is not optimal. Many practices lack the infrastructure to monitor patient adherence to recommended treatment and are slow to implement changes critical for effective management of patients with chronic conditions. Supporting Practices to Adopt Registry-Based Care (SPARC) will evaluate effectiveness and sustainability of a low-cost intervention designed to support work process change in primary care practices and enhance focus on population-based care through implementation of a diabetes …

Intrinsic Religiousness And Spirituality As Predictors Of Mental Health And Positive Psychological Functioning In Latter-Day Saint Adolescents And Young Adults, Kawika Allen, Peter W. Sanders, P. Scott Richards, Lane Fischer, David T. Morgan, Richard W. Potts

Faculty Publications

We investigated the relationships between religiousness and spirituality and various indicators of mental health and positive psychosocial functioning in three separate samples of college students. A total of 898 students at Brigham Young University participated in the three studies. The students ranged in age from 17 to 26 years old, with the average age of 20.9 across all three samples. Our results indicate that intrinsic religiousness, spiritual maturity, and self-transcendence were significantly predictive of better mental health and positive functioning, including lower levels of depression, anxiety, and obsessivecompulsiveness, and higher levels of global self-esteem, identity integration, moral selfapproval, and meaning …

Common Genetic Variants Influence Human Subcortical Brain Structures, Derrek P. Hibar, Jason L. Stein, Miguel E. Renteria, Alejandro Arias-Vasquez, John Blangero, Anderson M. Winkler, Joanne E. Curran, Thomas D. Dyer, Peter T. Fox, Ravi Duggirala

School of Medicine Publications

The highly complex structure of the human brain is strongly shaped by genetic influences. Subcortical brain regions form circuits with cortical areas to coordinate movement, learning, memory and motivation, and altered circuits can lead to abnormal behaviour and disease. To investigate how common genetic variants affect the structure of these brain regions, here we conduct genome-wide association studies of the volumes of seven subcortical regions and the intracranial volume derived from magnetic resonance images of 30,717 individuals from 50 cohorts. We identify five novel genetic variants influencing the volumes of the putamen and caudate nucleus. We also find stronger evidence …

Faculty Observables And Self-Reported Responsiveness To Academic Dishonesty, Robert T. Burrus, Jr., Adam T. Jones, William H. Sackley, Michael Walker

Administrative Issues Journal

Prior to 2009, a mid-sized public institution in the southeast had a faculty-driven honor policy characterized by little education about the policy and no tracking of repeat offenders. An updated code, implemented in August of 2009, required that students sign an honor pledge, created a formal student honor board, and developed a process to track and hold accountable, repeat offenders. Self-reported data on faculty vigilance to detect and punish cheating is collected both prior to and after a change in the honor code at a mid-sized public institution in the southeast. We find that, at the time of the first …