Medicine and Health Sciences Commons^™

The Psychological Response To A Low Carbohydrate Ketogenic Diet In Combination With A Six-Week Strength Training Protocol, Matthew T. Thorp

Masters Theses, 2010-2019

The aim of the present study was to determine whether or not long-term adherence to a Low-Carbohydrate Ketogenic Diet (LCKD) combined with a powerlifting strength training protocol could produce a positive psychological response. This six-week randomized control trial consisted of a treatment (LCKD) group (7% carbohydrates, 50% fat and 45% protein) and a control (CON) group (ad libitum). Both groups completed a validated powerlifting training protocol, as well as the Hospital Anxiety and Depression Scale and the Profile of Mood States. Multivariate testing and general linear modeling statistical analyses were used to compare psychological response between groups (p < 0.05) and found that there was a significant decrease in anxiety over the duration of six-weeks among both groups. No other psychological responses, including negative responses, were found to be significant. All participants significantly improved one-repetition max bench press, back squat, and deadlift (p < 0.05). The main findings of this study suggest that some positive psychological responses exist from long-term LCKD adherence, as well as potential increases in strength performance.

2015 Create Day Presentations In The Jdc, Daniel G. Kipnis, Msi

Jefferson Digital Commons News

Collaborative Research and Evidence Among Therapists and Educators (CREATE) Day is a clinical education program presented by occupational therapy graduate students in partial fulfillment of the Master of Science degree in Occupational Therapy at Thomas Jefferson University. Students conduct a systematic review of the literature on key topic areas that reflect current occupational therapy practice trends. The presentations include an introduction of the topic literature.

The latest round of 2015 Collaborative Research and Evidence Among Therapists and Educators (CREATE) Day presentations have been loaded into the Jefferson Digital Commons

Transitional Care Of Adult Patients With Diabetes Following Hospitalizations, Eric Tobin

Doctor of Nursing Practice Final Manuscripts

Purpose: The purpose of this evidence-based practice project was to incorporate a diabetes transitional care program using group visits to improve self-care management behaviors and glycemic control in diabetic patients at a southern California hospital.

Background: Diabetes is a challenging healthcare problem associated with significant mortality and morbidity issues. In 2012, 29.1 million people, or 9.3% of the U.S. population, were diagnosed with diabetes, and 28.9 million of those patients were 20 years of age and older. Today, diabetes is of epidemic proportion worldwide, and a projection of 5.4% of the adult population will have diabetes by 2025. The …

Differences In Substance Use, Sexual Behavior, And Demographic Factors By Level Of "Outness" To Friends And Family About Being A Male-For-Male Escort, Christian Grov, Raymond L. Moody, Hawk Kinkaid

Publications and Research

Male sex work (i.e., escorting) is a stigmatized profession and men in the sex industry may hide their involvement to avoid negative social consequences. There is limited research comparing men who are out about being an escort to their friends and/or family with those out to neither friends nor family. Data were taken from a 2013 online study of male escorts who were categorized into three groups based on outness patterns—friends only (48.9%, n = 193), friends and family (26.6%, n = 105), or neither friends nor family (23.5%, n = 93)—and compared on demographic and behavioral variables. We hypothesized …

The Influence Of Emotional Intelligence On Leadership Emergence And Leadership Styles, Grace E. Mccullough

Mahurin Honors College Capstone Experience/Thesis Projects

The aim of the current study was to determine the relationship between emotional intelligence and leadership emergence and transformational, transactional, and passive-avoidant leadership styles. Prior research has indicated that emotional intelligence is positively correlated with leader effectiveness. However, the relationship between emotional intelligence and additional aspects of leadership and leadership styles has not been thoroughly investigated. The current study hypothesized that emotional intelligence would be positively correlated with leadership emergence, and transformational and transactional leadership styles, and negatively correlated with a passive-avoidant leadership style. Additionally, it was hypothesized that leadership emergence would be positively correlated with transformational and transactional leadership …

A Patient With Polymerase E1 Deficiency (Pole1): Clinical Features And Overlap With Dna Breakage/Instability Syndromes., Isabelle Thiffault, Carol Saunders, Janda Jenkins, Nikita Raje, Kristi Canty, Mukta Sharma, Lauren Grote, Holly I. Welsh, Emily Farrow, Greyson Twist, Neil Miller, David Zwick, Lee Zellmer, Stephen F. Kingsmore, Nicole P. Safina

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Chromosome instability syndromes are a group of inherited conditions associated with chromosomal instability and breakage, often leading to immunodeficiency, growth retardation and increased risk of malignancy.

CASE PRESENTATION: We performed exome sequencing on a girl with a suspected chromosome instability syndrome that manifested as growth retardation, microcephaly, developmental delay, dysmorphic features, poikiloderma, immune deficiency with pancytopenia, and myelodysplasia. She was homozygous for a previously reported splice variant, c.4444 + 3A > G in the POLE1 gene, which encodes the catalytic subunit of DNA polymerase E.

CONCLUSION: This is the second family with POLE1-deficency, with the affected individual demonstrating a more …

Examining Monaural And Binaural Measures Of Phase-Locking As A Function Of Age, Larissa M. Heckler

Dissertations, 2014-2019

Understanding speech in the presence of background noise is a common complaint of middle-aged and older listeners with clinically normal audiograms. There is great interest in understanding how age-related changes in auditory physiology make it harder for older adults to understand speech in difficult listening situations, compared to young listeners. It was recently reported that middle-aged and older normal-hearing listeners showed frequency-dependent, age-related declines in the behavioral and physiological detection of interaural phase differences (Grose & Mamo, 2010; Ross et al, 2007). There is also evidence of an age-related, frequency-dependent decline in the frequency-following response (FFR) (Clinard et al., 2010), …

Training To Avoid Distractions, Cara E. Sanderson

Dissertations, 2014-2019

Introduction: Auditory training has been extensively studied and applied to training software that is currently available for children with attention, hearing, or speech/language difficulties. The extent to which training generalizes, or transfers to an untrained task, is of great theoretical value. To our knowledge, there has not been a study that examines transference to a non-sensory masking task.

Methods: 16 adults without ADHD were trained in a contralateral masking task over the course of two days, with 900 trials per day. False alarm rates, thresholds, and reaction times were measured. Pre- and post-tests of contralateral and informational masking were conducted …

Effect Of Adaptive Frequency Lowering On Phoneme Identification And Sound Quality Of Music In Hearing-Impaired Listeners, Kaitlyn A. Sabri

Dissertations, 2014-2019

The most common type and configuration of hearing loss seen in clinics is high frequency sensorineural hearing loss. High-frequency hearing losses can lead to difficulties understanding speech in noise. Traditional amplification can aid in audibility of high-frequency information; however, its success is limited due to acoustic feedback, output limitations of the hearing aids, and loudness discomfort (Bohnert, Nyffeler, & Keilmann, 2010, Turner & Cummings, 1999). Cochlear dead regions further hinder the success of traditional hearing aids, as speech recognition may not improve with increased audibility (Turner & Cummings, 1999). Frequency-lowering algorithms, developed by four major hearing aid manufacturers, attempt to …

Training Graduate Clinicians To Implement Speech Language Pathology, Occupational Therapy And Applied Behavior Analysis Goals In Their Treatment Sessions, Courtney E. Powers

Masters Theses, 2010-2019

Children with Autism Spectrum Disorder (ASD) often receive a multitude of treatment services. Among those services are speech language pathology, occupational therapy services, and applied behavior analysis. This study will focus on developing the skill sets of the three disciplines among graduate clinicians through training and coaching procedures. One graduate student from the applied behavior analysis track trained three graduate student clinicians, one from each discipline, on the individual goals of each discipline. These trainings occurred within the framework of a systematic multiple baseline design. After the mastery criterion was met through training, a bug-in-ear audio communication system was used …

Physical Feature Encoding And Word Recognition Abilities Are Altered In Children With Intractable Epilepsy: Preliminary Neuromagnetic Evidence, Maria Pardos, Milena Korostenskaja, Jing Xiang, Hisako Fujiwara, Ki H. Lee, Paul S. Horn, Anna Byars, Jennifer Vannest, Yingying Wang, Nat Hemasilpin, Douglas F. Rose

Center for Brain, Biology, and Behavior: Faculty Publications

Objective evaluation of language function is critical for children with intractable epilepsy under consideration for epilepsy surgery. The purpose of this preliminary study was to evaluate word recognition in children with intractable epilepsy by using magnetoencephalography (MEG). Ten children with intractable epilepsy (M/F 6/4, mean ± SD 13.4 ± 2.2 years) were matched on age and sex to healthy controls. Common nouns were presented simultaneously from visual and auditory sensory inputs in “match” and “mismatch” conditions. Neuromagnetic responses M1, M2, M3, M4, and M5 with latencies of ∼100ms, ∼150ms, ∼250ms, ∼350ms, and ∼450ms, respectively, elicited during the “match” condition were …

Is Younger Really Better? Age Differences In Emotion Perception, Kaitlyn Snyder

Mahurin Honors College Capstone Experience/Thesis Projects

Previous research suggests that younger adults outperform older adults on emotion-matching tasks because emotion recognition ability declines with age. These studies involved tasks in which participants identified a target emotion by selecting from multiple verbal labels. The use of multiple verbal labels placed great cognitive demand on participants, influencing the results that were found in such studies. In the present study, a computer emotion-matching task was used to determine differences between younger and older adults when presented with a target stimulus expressing one of five emotions (anger, fear, disgust, happiness, and sadness) and asked to match the target emotion to …

The Effect Of An Educational Intervention On Knowledge And Intent To Participate In Cervical Cancer Screening, Ann Marie Trapp

Evidence-Based Practice Project Reports

Globally, cervical cancer ranks third among cancers affecting women (Arbyn et al., 2013). In the United States, approximately 12,000 women are diagnosed with cervical cancer and approximately 4,000 women die yearly (Centers for Disease Control and Prevention, 2014). Papanicolaou (Pap) screening is an effective means of detecting precancerous cell changes of the cervix with early cervical cancer diagnosis carrying a 91% five-year survival rate (Gonzalez et al., 2012). The purpose of this evidence-based practice project was to identify interventions that increase adherence to cervical cancer screening and to implement best practices to reduce unnecessary deaths related to late diagnoses of …

Drug Predictive Cues Activate Aversion-Sensitive Striatal Neurons That Encode Drug Seeking, Daniel S. Wheeler, Mykel A. Robble, Emily M. Hebron, Matthew J. Dupont, Amanda L. Ebben, Robert A. Wheeler

Biomedical Sciences Faculty Research and Publications

Drug-associated cues have profound effects on an addict’s emotional state and drug-seeking behavior. Although this influence must involve the motivational neural system that initiates and encodes the drug-seeking act, surprisingly little is known about the nature of such physiological events and their motivational consequences. Three experiments investigated the effect of a cocaine-predictive stimulus on dopamine signaling, neuronal activity, and reinstatement of cocaine seeking. In all experiments, rats were divided into two groups (paired and unpaired), and trained to self-administer cocaine in the presence of a tone that signaled the immediate availability of the drug. For rats in the paired group, …

Significance Of Qrs Duration In Non-St Elevation Myocardial Infarction., Chinualumogu Nwakile, Bhaskar Purushottam, Vikas Bhalla, Daniel Ukpong, Mahek Shah, Jeong Yun, D Lynn Morris, Vincent M. Figueredo, M.D.

Division of Cardiology Faculty Papers

No abstract provided.

Adiponectin Attenuates Lung Fibroblasts Activation And Pulmonary Fibrosis Induced By Paraquat., Rong Yao, Yu Cao, Ya-Rong He, Wayne Bond Lau, Zhi Zeng, Zong-An Liang

Department of Emergency Medicine Faculty Papers

Pulmonary fibrosis is one of the most common complications of paraquat (PQ) poisoning, which demands for more effective therapies. Accumulating evidence suggests adiponectin (APN) may be a promising therapy against fibrotic diseases. In the current study, we determine whether the exogenous globular APN isoform protects against pulmonary fibrosis in PQ-treated mice and human lung fibroblasts, and dissect the responsible underlying mechanisms. BALB/C mice were divided into control group, PQ group, PQ + low-dose APN group, and PQ + high-dose APN group. Mice were sacrificed 3, 7, 14, and 21 days after PQ treatment. We compared pulmonary histopathological changes among different …

Using Education And A Prevention Protocol Tool To Decrease The Incidence Of Pressure Ulcers In A Nursing Home, Kristina L. Scalzitti

Evidence-Based Practice Project Reports

Over 1.3 million persons are residents in nursing homes (NHs); one in ten have pressure ulcers. The purpose of this evidence based practice project was to determine if implementation of a pressure ulcer prevention tool, along with staff education, decreases the incidence of pressure ulcers within the NH. Florence Nightingale’s Environmental Model and the Stetler Model were used to guide this project. The setting was a NH in northwest Indiana. Eleven nurses attended a 15 minute educational session on pressure ulcer prevention and implementation of the Pressure Ulcer Prevention Protocol Intervention (PUPPI) tool. PowerPoint slides were distributed and flyers about …

The Physiological Effects Of A Cross Country Bike Ride On Novice Cyclists, Wade Weatherholt

Mahurin Honors College Capstone Experience/Thesis Projects

Purpose: The physiological responses and adaptations experienced by novices engaging in cross-country cycling have received little attention in the scientific literature. Such endeavors typically involve a sizeable increase in physical activity for most individuals, but the acute and chronic effects of such an endurance feat are not well understood. Similarly, research shows that experienced cyclists often demonstrate osteoporosis in the spine, linked to many years of training accompanied by little or no weight bearing stress upon the axial skeleton. Greater understanding of these issues is needed, as long distance cycling has increased in popularity in recent years, and exercise professionals …

Barriers To Care And Buyer Behavior In Relation To Oral Hygiene, Allison E. Mccutchen

Mahurin Honors College Capstone Experience/Thesis Projects

How much of an impact do advertising, brand loyalty, and socioeconomic status have on the overall oral-health knowledge and dental care product purchases of consumers? A survey was distributed to collect data on consumers’ background, oral hygiene purchasing habits, and decision making rationales. It was assumed that those with minimal access to care and minimal oral-health knowledge would be purchasing products based on sale prices, or the promise of improved esthetics, whereas consumers with increased access to care would likely make their purchasing decisions based on the recommendations of a dental professional and be potentially more interested in trying new …

Rlt-S: A Web System For Record Linkage, Robert H. Aseltine, Sanguthevar Rajasekaran, Abdullah-Al Mamun

UCHC Articles - Research

Abstract

Background

Record linkage integrates records across multiple related data sources identifying duplicates and accounting for possible errors. Real life applications require efficient algorithms to merge these voluminous data sources to find out all records belonging to same individuals. Our recently devised highly efficient record linkage algorithms provide best-known solutions to this challenging problem.

Method

We have developed RLT-S, a freely available web tool, which implements our single linkage clustering algorithm for record linkage. This tool requires input data sets and a small set of configuration settings about these files to work efficiently. RLT-S employs exact match clustering, blocking on …

The Physical Death Of Jesus Christ: The “Swoon Theory” And The Medical Response, Kate Hill

Spring 2015, Faith and Science

The Crucifixion and the Resurrection are two of the most important foundational elements of the Christian religion. There are some skeptics, however, who believe that the Crucifixion was not “completed”, and that Jesus never actually died on the cross. If this hypothesis were true, it would call the entire Christian system of beliefs into question. One theory of this sort that grew in popularity with 18^th century rationalists became known as the “Resuscitation Theory”, or “Swoon Theory”. Put simply, this theory states that Jesus did not actually die during the Crucifixion. Rather, he simply “swooned” and fell unconscious while …

Emergence Of Multidrug Resistant Influenza A(H1n1)Pdm09 Virus Variants In An Immunocompromised Child Treated With Oseltamivir And Zanamivir., Daisuke Tamura, Roberta L. Debiasi, Margaret Okomo-Adhiambo, Vasiliy P. Mishin, Angela P. Campbell, Brett Loechelt, Bernhard L. Wiedermann, Alicia M. Fry, Larisa V. Gubareva

Pediatrics Faculty Publications

Prolonged treatment of an immunocompromised child with oseltamivir and zanamivir for A(H1N1)pdm09 virus infection led to the emergence of viruses carrying H275Y and/or E119G in the neuraminidase. When phenotypically evaluated by neuraminidase inhibition, the dual H275Y-E119G substitution caused highly reduced inhibition by four neuraminidase inhibitors including oseltamivir, zanamivir, peramivir and laninamivir.

Effects Of Multimodal Fever Education On Parents Of Febrile Children, Teresa S. Parkhouse

Evidence-Based Practice Project Reports

Insufficient knowledge regarding the physiology and appropriate management of fever in children often contributes to an increased parental anxiety, inappropriate antipyretic use, and overutilization of medical resources (Chang, Liu, & Huang, 2013; Crocetti, Moghbeli, & Serwint, 2001; Schmitt, 1980). Parental concerns regarding childhood fever can lead to an overuse of health care resources as febrile illness in children accounts for approximately 20% of emergency department visits, 30% of office visits, and over 50% of after-hour phone calls to private physicians (Zomorrodi & Attia, 2008). Research shows that multidimensional educational interventions are most effective in improving parental management of fever (Young …

The Importance Of Educating Dental And Dental Hygiene Students On The Correlation Between Vitamin D Deficiency And Dental Caries, Sara Brown

Mahurin Honors College Capstone Experience/Thesis Projects

Recent studies from the U.S. National Library of Medicine have shown that vitamin D deficiency is rapidly increasing among the adult population. Vitamin D deficiency has many effects on the body, such as bone pain and muscle weakness. A strong correlation has been noticed in humans with vitamin D deficiency and decreased exposure to natural sunlight, which is vital to absorb the vitamin D they have ingested. Those suffering from milk allergies or are following a strict vegan diet may also have some implication of a vitamin D deficiency. Recent studies (Hujoel, 2012) have also shown that there is a …

Critical Synthesis Package: The Kalamazoo Consensus Statement Assessment Tools, Michelle Yoon, Veronica Michaelsen

E-Learning Modules

This Critical Synthesis Package resource contains 1) a Critical Analysis of the psychometric properties and the application to health science education of the Kalamazoo Consensus Statement Assessment Tools and 2) a copy of each of the three instruments comprising the Kalamazoo Consensus Statement Assessment Tools developed by Elizabeth A. Rider, MSW, MD.

The Kalamazoo Consensus Statement (KCS) Tools are three content-valid, paper-based instruments that assess physician-patient communication skills. The Kalamazoo Essential Elements Communication Checklist (KEECC) is the original instrument. The Kalamazoo Essential Elements Communication Checklist-Adapted (KEECC-A) is a newer, adapted, construct-valid version, which was then further adapted into another multi-rater …

The Star Rating System And Medicare Advantage Plans, Lisa Sprague

National Health Policy Forum

With nearly 30 percent of Medicare beneficiaries opting to enroll in Medicare Advantage (MA) plans instead of fee-for-service Medicare, it’s safe to say the MA program is quite popular. The Centers for Medicare & Medicaid Services (CMS) administers a Star Ratings program for MA plans, which offers measures of quality and service among the plans that are used not only to help beneficiaries choose plans but also to award additional payments to plans that meet high standards. These additional payments, in turn, are used by plans to provide additional benefits to beneficiaries or to reduce cost sharing—added features that are …

Gold Mining And Unequal Exchange In Western Amazonia: A Theoretical Photo Essay, Gordon L. Ulmer

disClosure: A Journal of Social Theory

I combine fieldwork photography and ethnographic documentation of gold mining in Madre de Dios, Peru, to examine the localized material, social, environmental, and health outcomes of the global gold boom. This 'theoretical photo essay’ examines how local and global forces coalesce around gold mining and influence peoples and environments in Western Amazonia. I use embodiment theory in anthropology, ecological economics, and theories of underdevelopment to understand local consequences of the global gold trade and to elucidate how opulence and the machinations of capital accumulation in economic centers of the world occur at the expense of human lives and environments in …

Effect Of Novel Dietary Supplement On Metabolism In Vitro And In Vivo, Robert A. Vaughan, Ailish C. White, Jason R. Beam, Nicholas P. Gannon, Randi Garcia-Smith, Roy M. Salgado, Marco Bisoffi, Kristina A. Trujillo, Carole A. Conn, Christine M. Mermier

Health Sciences and Kinesiology Faculty Articles

Obesity is an increasingly prevalent and preventable morbidity with multiple behavioral, surgical and pharmacological interventions currently available. Commercial dietary supplements are often advertised to stimulate metabolism and cause rapid weight and/or fat loss, although few well-controlled studies have demonstrated such effects. We describe a commercially available dietary supplement (purportedly containing caffeine, catechins, and other metabolic stimulators) on resting metabolic rate in humans, and on metabolism, mitochondrial content, and related gene expression in vitro. Human males ingested either a placebo or commercially available supplement (RF) in a randomized double-blind placebo-controlled cross-over fashion. Metabolic rate, respiratory exchange ratio, and blood pressure were …

The Lonely Hour: Barriers To Seeking Help, Gregory Cannon Do

Department of Family Medicine

No abstract provided.

Physician, Mother, Patient: An Autoethnographic Examination Of Post Partum Depression, Tara Franhouser Do

Department of Family Medicine

No abstract provided.