Medicine and Health Sciences Commons^™

Practice Matters: Screening And Monitoring Hyperlipidemia, M. Laurie Branstetter Dnp, Maria E. Main, Tonya Bragg-Underwood Dnp

International Journal of Faith Community Nursing

Abstract

The purpose of this article is to provide Faith Community Nurses with current information on hyperlipidemia, a chronic disease responsible for the leading cause of death worldwide. Current guidelines for cholesterol screening and a risk calculator resource for estimating cardiovascular risk are provided. Myths and truths are presented for review with patients. Suggestions and resources for lifestyle modifications and patient education are included. Faith Community Nurses are at the center of community health and actively involved with improving health outcomes related to chronic disease.

A Combination Sms And Transportation Reimbursement Intervention To Improve Hiv Care Following Abnormal Cd4 Test Results In Rural Uganda: A Prospective Observational Cohort Study, Mark J. Siedner, Data Santorino, Alexander J. Lankowski, Michael Kanyesigye, Mwebesa B. Bwana, Jessica E. Haberer, David R. Bangsberg

OHSU-PSU School of Public Health Faculty Publications and Presentations

Background: Up to 50 % of HIV-infected persons in sub-Saharan Africa are lost from care between HIV diagnosis and antiretroviral therapy (ART) initiation. Structural barriers, including cost of transportation to clinic and poor communication systems, are major contributors.

Methods: We conducted a prospective, pragmatic, before-and-after clinical trial to evaluate a combination mobile health and transportation reimbursement intervention to improve care at a publicly operated HIV clinic in Uganda. Patients undergoing CD4 count testing were enrolled, and clinicians selected a result threshold that would prompt early return for ART initiation or further care. Participants enrolled in the pre-intervention period (January – …

Inhaled Nitric Oxide As An Adjunctive Treatment For Cerebral Malaria In Children: A Phase Ii Randomized Open-Label Clinical Trial, Juliet Mwanga-Amumpaire, Ryan W. Carroll, Elisabeth Baudin, Elisabeth Kemigisha, Dorah Nampijjah, Kenneth Mworozi, Data Santorino, Dan Nyehangane, Daniel I. Nathan, Pierre De Beaudrap, Jean-Francois Etard, Martin Feelish, Bernadette O. Fernandez, Annie Berssenbrugge, David Bangsberg, Kenneth D. Bloch, Yap Boum Ii, Warren M. Zapol

OHSU-PSU School of Public Health Faculty Publications and Presentations

Background. Children with cerebral malaria (CM) have high rates of mortality and neurologic sequelae. Nitric oxide (NO) metabolite levels in plasma and urine are reduced in CM.

Methods. This randomized trial assessed the efficacy of inhaled NO versus nitrogen (N2) as an adjunctive treatment for CM patients receiving intravenous artesunate.We hypothesized that patients treated with NO would have a greater increase of the malaria biomarker, plasma angiopoietin-1 (Ang-1) after 48 hours of treatment.

Results. Ninety-two children with CM were randomized to receive either inhaled 80 part per million NO or N₂ for 48 or more hours. Plasma Ang-1 levels …

Epidermal Growth Factor Mediated Healing In Stem Cell-Derived Vocal Fold Mucosa, Liliana Palencia, Amritava Das, Sean P. Palecek, Susan L. Thibeault, Ciara Leydon

Communication Disorders Faculty Publications

Background: The goal of vocal fold wound healing is the reconstitution of functional tissue, including a structurally and functionally intact epithelium. Mechanisms underlying reepithelialization in vocal folds are not known, although it is suspected that healing involves the interplay between several growth factors. We used a three-dimensional human embryonic stem cell-derived model of vocal fold mucosa to examine the effects of one growth factor, exogenous epidermal growth factor (EGF), on wound healing. Materials and methods: A scratch wound was created in the in vitro model. Rate of wound healing, epidermal growth factor receptor (EGFR) activation, and cell proliferation after injury …

The Scoop, Vol. 2 Issue 3-4, Summer 2015, Health Sciences Library

Volume 2

Latest news and events from the Health Sciences Library in our monthly newsletter for Summer 2015.

Increasing Emotion Word Productions In Children With Language Impairment With A Social Communication Intervention, Madelane Kate Dixon

Theses and Dissertations

This thesis examines the efficacy of a social communication intervention in increasing the emotion word productions in school-aged children with language impairment (LI). The study had a multiple baseline single subject design in which 5 children between the ages of 6 and 11 received 20 intervention sessions, each lasting 20 minutes. Intervention activities included reading and discussing children's books, enacting the stories using toys, and journal writing to reflect on experiences in each session. Emotion word productions during intervention sessions were coded for total productions within the categories of happiness, anger, sadness, fear, surprise, and disgust. Productions were also coded …

Community-Based Participatory Research To Adapt Health Measures For Use By People With Developmental Disabilities, Christina Nicolaidis, Dora Raymaker, Marsha Katz, Mary Oschwald, Rebecca Goe, Sandra Leotti, Leah Grantham, Eddie Plourde, Janice Salomon, Rosemary B. Hughes, Laurie E. Powers, Partnering With People With Disabilities To Address Violence Consortium

School of Social Work Faculty Publications and Presentations

Background: People with developmental disabilities (DD) are often not included as participants in research owing to a variety of ethical and practical challenges. One major challenge is that traditional measurement instruments may not be accessible to people with DD. Participatory research approaches promise to increase the participation of marginalized communities in research, but few partnerships have successfully used such approaches to conduct quantitative studies people with DD.

Objective: To use a community-based participatory research (CBPR) approach to create an accessible, computer-assisted survey about violence and health in people with DD, and to psychometrically test adapted health instruments.

Methods …

Translating Pharmacogenetics To Clinical Practice: Do Cytochrome P450 2d6 Ultrarapid Metabolizers Need Higher Atomoxetine Doses?, Jose De Leon

Psychiatry Faculty Publications

No abstract provided.

Effects Of Antiretroviral Therapy On Kaposi’S Sarcoma–Associated Herpesvirus (Kshv) Transmission Among Hiv-Infected Zambian Children, Landon Olp, Veenu Minhas, Clement Gondwe, Chipepo Kankasa, Janet M. Wojcicki, Charles Mitchell, John T. West, Charles Wood

Nebraska Center for Virology: Faculty Publications

Background: The risk of Kaposi’s sarcoma–associated herpesvirus (KSHV) acquisition among children is increased by HIV infection. Antiretroviral therapy (ART) was recently made widely available to HIV-infected children in Zambia. However, the impact of early ART on KSHV transmission to HIV-infected children is unknown.

Methods: We enrolled and followed a cohort of 287 HIV-exposed, KSHV-negative children under 12 months of age from Lusaka, Zambia, to identify KSHV seroconversion events. Potential factors associated with KSHV infection—with an emphasis on HIV, ART, and immunological measures—were assessed through structured questionnaires and blood analyses. Incidence rate, Kaplan- Meier, and multivariable Cox regression models were used …

Embracing Multiple Definitions Of Learning, Andrew B. Barron, Eileen A. Hebets, Thomas A. Cleland, Courtney L. Fitzpatrick, Mark E. Hauber, Jeffrey R. Stevens

Eileen Hebets Publications

Definitions of learning vary widely across disciplines, driven largely by different approaches used to assess its occurrence. These definitions can be better reconciled with each other if each is recognized as coherent with a common conceptualization of learning, while appreciating the practical utility of different learning definitions in different contexts.

Learning is a major focus of research in psychology, neuro- science, behavioral ecology, evolutionary theory, and computer science, as well as in many other disciplines. Despite its conceptual prevalence, definitions of learning differ enormously both within and between these disciplines, and new definitions continue to be proposed [1]. Ongoing disputes …

Impaired Synaptic Development In A Maternal Immune Activation Mouse Model Of Neurodevelopmental Disorders, Pierluca Coiro, Ragunathan Padmashri, Anand Suresh, Elizabeth Spartz, Gurudutt Pendyala, Shinnyi Chou, Yoosun Jung, Brittney Meays, Shreya Roy, Nagsen Gautam, Yazen Alnouti, Ming Li, Anna Dunaevsky

Department of Psychology: Faculty Publications

Both genetic and environmental factors are thought to contribute to neurodevelopmental and neuropsychiatric disorders with maternal immune activation (MIA) being a risk factor for both autism spectrum disorders and schizophrenia. Although MIA mouse offspring exhibit behavioral impairments, the synaptic alterations in vivo that mediate these behaviors are not known. Here we employed in vivo multiphoton imaging to determine that in the cortex of young MIA offspring there is a reduction in number and turnover rates of dendritic spines, sites of majority of excitatory synaptic inputs. Significantly, spine impairments persisted into adulthood and correlated with increased repetitive behavior, an ASD relevant …

Hla-Dqa1 And Plcg2 Are Candidate Risk Loci For Childhood-Onset Steroid-Sensitive Nephrotic Syndrome., Rasheed A. Gbadegesin, Adebowale Adeyemo, Nicholas J A Webb, Larry A A. Greenbaum, Asiri Abeyagunawardena, Shenal Thalgahagoda, Arundhati Kale, Debbie Gipson, Tarak Srivastava, Jen-Jar Lin, Deepa Chand, Tracy E. Hunley, Patrick D. Brophy, Arvind Bagga, Aditi Sinha, Michelle N. Rheault, Joanna Ghali, Kathy Nicholls, Elizabeth Abraham, Halima S. Janjua, Abiodun Omoloja, Gina-Marie Barletta, Yi Cai, David D. Milford, Catherine O'Brien, Atif Awan, Vladimir Belostotsky, William E. Smoyer, Alison Homstad, Gentzon Hall, Guanghong Wu, Shashi Nagaraj, Delbert Wigfall, John Foreman, Michelle P. Winn, Mid-West Pediatric Nephrology Consortium

Manuscripts, Articles, Book Chapters and Other Papers

Steroid-sensitive nephrotic syndrome (SSNS) accounts for >80% of cases of nephrotic syndrome in childhood. However, the etiology and pathogenesis of SSNS remain obscure. Hypothesizing that coding variation may underlie SSNS risk, we conducted an exome array association study of SSNS. We enrolled a discovery set of 363 persons (214 South Asian children with SSNS and 149 controls) and genotyped them using the Illumina HumanExome Beadchip. Four common single nucleotide polymorphisms (SNPs) in HLA-DQA1 and HLA-DQB1 (rs1129740, rs9273349, rs1071630, and rs1140343) were significantly associated with SSNS at or near the Bonferroni-adjusted P value for the number of single variants that were …

Median Nerve Mobility Measurement Using A Motion Tracking Analysis Program: A Reliability Study, Consuelo Gonzalez-Suarez, Jan Nathleen Dizon, Belinda Cabungcal-Fidel, Ronald Christopher A. Cua, Valentine C. Dones, Peter Lesniewski, John C. Thomas

Internet Journal of Allied Health Sciences and Practice

Objective: To evaluate relative and absolute reliability and repeatability in assessing median nerve mobility at the level of the wrist and distal upper arm of the right upper extremity during wrist extension. Methods: Six healthy participants participated in the study. Median nerve mobility was captured three times at both sites using Sonocyte Turbo by two sonologists for a total of 72 video clips (36 for each site and 18 by each sonologist). Longitudinal movement was measured using Motion Tracking Analysis Program (MTAP) by the two assessors who were rehabilitation medicine residents. After one month, the assessors remeasured the longitudinal excursion …

Explaining The Contact Caveat: The Role Of Social Identity And Intergroup Threat, Jesse Acosta

Theses and Dissertations - UTB/UTPA

This project has attempted to offer an explanation for the differential roles of positive and negative contact, wherein negative contact more strongly predicts changes in prejudice than positive contact (Barlow et al., 2007). In an attempt to replicate and extend on this relationship, intergroup threat theory and social identity theory are incorporated in a model intended to explain this differential relationship. This study measured the attitudes of 227 Mexican Americans toward Caucasians and Mexican Immigrants. This analysis offers a partial replication of Barlow et al., with unfavorable attitudes toward Whites leading to stronger changes when contact was negative. When evaluating …

Improving Patient Flow With Data-Driven Patient Prioritization Method In The Emergency Department, Kar Way Tan, Sean Shao Wei Lam

Research Collection School Of Computing and Information Systems

We aim to improve the length-of-stay (LOS) of patients in the Emergency Department (ED) ambulatory care area. We propose the use of real-time computerized physician order entry data and ED patient flow management system to estimate the consultation time of patients re-entering the queue to consult a doctor again after receiving treatment or results of tests. The estimation allows decision-makers to apply dynamic prioritization strategies that help the ED to identify patients who can complete their ED treatment process quickly, freeing up resources in the ED and lowering overall LOS.

Examining Pharmacy Students’ Perceptions Of Clinical Faculty Mentoring Characteristics Influencing Students’ Decision To Pursue A Pharmacy Residency, Kin S. Ly

All Theses And Dissertations

The field of pharmacy is changing from a drug-distribution-centered model to a patient-centered integrated model whereby pharmacists are actively involved in patient care as part of an interdisciplinary team. To address the estimated pharmacy leadership crisis in the future and to prepare pharmacists to work in the changing healthcare landscape, national pharmacy organizations such as the American Society of Health-System Pharmacists (ASHP) and the American College of Clinical Pharmacy (ACCP) have stated that postgraduate pharmacy residency should be mandatory by 2020. Past pharmacy research literature has shown that while many factors influence students to pursue a pharmacy residency, there is …

Cancer In Louisiana: 2008-2012, Volume 30, Louisiana Tumor Registry, Lauren Maniscalco, Christina Lefante, Mei-Chin Hsieh, Patricia Andrews, Lisa Pareti, Lisa Pareti, Brent Mumphrey, Beth A. Schmidt, Xiangrong Li, Vivien W. Chen, Ian Landry, Xiao-Cheng Wu

Policy & Position Papers

Mission:

To collect and report complete, high-quality, and timely population-based cancer data in Louisiana to support cancer research, control, and prevention.

Vision:

To reduce suffering and death from cancer using information collected by the Louisiana Tumor Registry.

History:

Cancer registration in Louisiana began in 1947 at the Charity Hospital Tumor Registry in New Orleans. In 1974, as part of its Surveillance, Epidemiology and End Results (SEER) Program, the National Cancer Institute provided funds for a population-based cancer incidence and survival registry covering Jefferson, Orleans, and St. Bernard parishes. Five years later, the Louisiana Tumor Registry (LTR) was transferred to the …

Willingness To Test For Brca1/2 In High Risk Women: Influenced By Risk Perception And Family Experience, Rather Than By Objective Or Subjective Numeracy?, Talya Miron-Shatz, Yaniv Hanoch, Benjamin A. Katz, Glen M. Doniger, Elissa M. Ozanne

Dartmouth Scholarship

Genetic testing for breast and ovarian cancer can help target prevention programs, and possibly reduce morbidity and mortality. A positive result of BRCA1/2 is a substantial risk factor for breast and ovarian cancer, and its detection often leads to risk reduction interventions such as increased screening, prophylactic mastectomy and oophorectomy. We examined predictors of the decision to undergo cancer related genetic testing: perceived risk, family risk of breast or ovarian cancer, and numeracy as predictors of the decision to test among women at high risk of breast cancer. Stepwise regression analysis of survey responses from 459 women registered in the …

Obesity Early In Adulthood Increases Risk But Does Not Affect Outcomes Of Hepatocellular Carcinoma, Manal M. Hassan, Reham Abdel-Wahab, Ahmed Kaseb, Ahmed Shalaby, Alexandria Phan, Hashem El-Serag, Ernest Hawk, Jeff Morris, Kanwal Pratap Singh Raghav, Ju-Seog Lee, Jean-Nicolas Vauthey, Gehan Bortus, Harrys Torres, Christopher Amos, Robert Wolff, Donghui Li

Dartmouth Scholarship

Despite the significant association between obesity and several cancers, it has been difficult to establish an association between obesity and hepatocellular carcinoma (HCC). Patients with HCC often have ascites, making it a challenge to accurately determine body mass index (BMI), and many factors contribute to the development of HCC. We performed a case–control study to investigate whether obesity early in adulthood affects risk, age of onset, or outcomes of patients with HCC.

Functional Neuroimaging Distinguishes Posttraumatic Stress Disorder From Traumatic Brain Injury In Focused And Large Community Datasets., Daniel G Amen, Cyrus A Raji, Kristen Willeumier, Derek Taylor, Robert Tarzwell, Andrew B. Newberg, Md, Theodore A Henderson

Department of Radiology Faculty Papers

BACKGROUND: Traumatic brain injury (TBI) and posttraumatic stress disorder (PTSD) are highly heterogeneous and often present with overlapping symptomology, providing challenges in reliable classification and treatment. Single photon emission computed tomography (SPECT) may be advantageous in the diagnostic separation of these disorders when comorbid or clinically indistinct.

METHODS: Subjects were selected from a multisite database, where rest and on-task SPECT scans were obtained on a large group of neuropsychiatric patients. Two groups were analyzed: Group 1 with TBI (n=104), PTSD (n=104) or both (n=73) closely matched for demographics and comorbidity, compared to each other and healthy controls (N=116); Group 2 …

Characterization Of R-Ketorolac As A Single Enantiomer Selective Inhibitor Of Cdc42 And Rac1 In Ovarian Cancer, Shelby Ray Kenney Jr.

Biomedical Sciences ETDs

Ovarian cancer is the 5th leading cause of cancer death for women in the United States and is frequently diagnosed at an advanced stage with multiple metastases. Rho family GTPases contribute to metastasis through regulation of the actin cytoskeleton, cell motility, cell-cell and cell-extracellular matrix adhesion and these GTPases are altered in a number of human cancers. High throughput screening and in silico modeling identified the R-enantiomer, but not S-enantiomer, of the non-steroidal anti-inflammatory drug ketorolac as a novel inhibitor of Rac1 and Cdc42. Ketorolac is administered as a racemic mix of both enantiomers and is used clinically for surgical …

2015-2016 Lsu Health Sciences Center In New Orleans Catalog/Bulletin, Office Of The Registrar

Catalogs and Bulletins

No abstract provided.

Message, H Vinod Bhat Dr

Manipal Journal of Nursing and Health Sciences

NA

Effect Of Auditory Cues On Gait Among Patients With Parkinson’S Disease In South India, Lekshmi Mohan Ms, Asha Sasikumar Ms, Thomas Iype, Babu P. K

Manipal Journal of Nursing and Health Sciences

Introduction: In Parkinson’s disease there is defective internal rhythm generation. There is some evidence that it can be overcome with external rhythmic cues. Objective: Evaluate the effect of auditory cues on gait among patients with Parkinson’s disease. Methodology: Experimental – One group pretest post-test design was adopted. The study was conducted on 30 patients with Parkinson’s disease attended the Department of Neurology, Medical College Hospital, Thiruvananthapuram. Samples were selected consecutively. Researcher collected data from the subjects using a semi structured interview schedule and Dynamic Gait Index Scale. The intervention was practice of gait listening to auditory cues by an electronic …

Effectiveness Of Interactive Session On Prevention Of Adolescent Suicide, Sara Varughese Ms, Linu Sara George Dr, Prima J J D'Souza Ms

Manipal Journal of Nursing and Health Sciences

Background: Suicide is the second leading cause of death among Indian adolescents. The school personnel play an important role in the prevention of adolescent suicides. Aims and objectives: The study aimed at assessing the knowledge on prevention of adolescent suicide as measured by a knowledge questionnaire and determine the effectiveness of an interactive session in terms of gain in knowledge scores. Materials and methods: The study comprised 68 high school teachers conveniently selected from eight English medium high schools of Udupi Taluk. One group pre-test post-test design was used. The pre-test on prevention of suicide was conducted on the first …

Materno Foetal Physiological Parameters In Sitting And Left Lateral Position During Non - Stress Test (Nst) Monitoring In Pregnancy: A Cross Over Study, Rachel Samuel Ms, Sushmitha Karkada Ms, Sweety Fermamdes Ms, Parvathi Bhat Dr

Manipal Journal of Nursing and Health Sciences

Introduction: The main goal of foetal observation is a healthy new born with a mother who is healthy. The non-stress test (NST) is a primary foetal surveillance tool. This study aimed to compare the maternal physiological parameters of antenatal women during NST monitoring between sitting and left lateral position and also to determine the foetal physiological parameters during NST monitoring in sitting position and left lateral position. Methods: The study was cross over design. The antenatal women between 34 to 40 weeks of gestation were randomly given the position as Group-A or Group-B position strategy. The setting of the study …

Reproductive Health Problems And Health Seeking Behaviour Among Adolescent Girls Of Udupi District, Karnataka, Swetha Pavithran Ms, Yashoda S Ms, Sangeetha Priyadarshini Ms, Baby S. Nayak Dr

Manipal Journal of Nursing and Health Sciences

Introduction: Adolescence is the period of transition from childhood to adulthood. This transition phase makes them vulnerable to a large variety of morbidities among adolescent girls. Reproductive tract infections (RTIs) are one of the most prevalent health morbidities among women throughout the world especially in developing countries. Objective: To identify the reproductive health problems and health seeking behaviour among adolescent girls in Udupi district, Karnataka. Methods: Cross sectional study was conducted to determine the reproductive health problems and health seeking behaviour of 400 adolescent girls between 14-18 years age group. A valid pre-tested, reliable reproductive health problems assessment scale and …

Anxiety And Coping Mechanisms Among Hiv Positive Patients, Sreelekshmi R Ms

Manipal Journal of Nursing and Health Sciences

Introduction: HIV or human immunodeficiency virus infection breaks down body’s immune system. In India HIV infection is associated with stigma and open discrimination.This chronic illness can have much deleterious effect on the patients’ physiological and psychological status. Thus, identification of anxiety and different coping strategies adopted by these patients are of prime importance. Methods: A descriptive survey was carried out to collect data from150 HIV positive patients who were on antiretroviral therapy through simple random sample technique (lottery method); the state anxiety inventory and Dr Kiran Rao’s coping checklist were used for collecting data. Result: Findings of the study showed …

Need Based Instructional Program On Care Competency Of Informal Care Givers For Chronic Renal Failure Patients At Home, Mukesh Kumar Mr, Rajesh Kumar Sharma Mr, Mahalingam

Manipal Journal of Nursing and Health Sciences

Introduction: Majority of patients with Chronic Renal Failure (CRF), Chronic Kidney Disease (CKD) and End Stage Renal Disease (ESRD) depends on their family and friends, to manage their chronic illness throughout the course of illness. Appropriate home care of CKD can help to prevent or delay the progression of illness. Methods: A pre-experimental study with quantitative approach was undertaken on 45 care givers of CKD patients with the objective to study the improvement in competency regarding home care through administration of an instructional programme and information booklet. The program and the booklet consisted information on nutritional management, rest and exercises, …

Awareness On Health And Social Welfare Benefits Among Beedi Workers – A Community Survey, Sudina M Ms, Ansuya B Ms, Alma Juliet Lakra Ms

Manipal Journal of Nursing and Health Sciences

Introduction: Beedi rolling is the major occupation of the women and children residing in many villages in the country providing employment to about 4.2 million beedi workers with the highest number in MadhyaPradesh (18.3%), followed by Andhra Pradesh (14.4%) and Tamil Nadu(13.8%). The beedi workers’ welfare fund consists of combination of schemes to improve the living conditions of beedi workers and their families. The study aimed at identifying awareness regarding these benefits among the beedi workers of the selected villages in Karnataka. Material and Methods: A descriptive study design was carried out among conveniently selected two hundred women between 20 …