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2015

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Articles 2581 - 2610 of 11981

Full-Text Articles in Medicine and Health Sciences

Integrating Clinical Training & Self-Care: Overview, Analysis & Recommendations For Relieving Stress Among Clinicians In Training, Erich Haezebrouck Aug 2015

Integrating Clinical Training & Self-Care: Overview, Analysis & Recommendations For Relieving Stress Among Clinicians In Training, Erich Haezebrouck

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

Numerous studies over the past two decades have highlighted the prevalence of stress, mental health disorders and interpersonal problems among psychologists. These statistics parallel those for students currently enrolled in clinical psychology graduate programs where such problems have become even more severe. This results in a significant ethical issue in that clinician competency is negatively impacted by emotional problems. This paper seeks to provide an analysis of current self-care literature. The importance of addressing graduate student self-care is first explored and followed by a literature review on interventions that have been successful in maintaining trainee wellness and competence. Recommendations to …


Best Practices In Team-Based Treatment Termination, Leslie Minna Aug 2015

Best Practices In Team-Based Treatment Termination, Leslie Minna

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

Termination of psychological treatment is a necessary part of the therapeutic process, but it can pose complex clinical, ethical, legal, logistical, and social challenges. This complexity becomes even more evident in the current era of treatment delivered by a team of healthcare professionals. Appropriate termination will usually involve a team decision and synthesis of the various team members’ recommendations for appropriate follow-up, medications, or transfer of care into an integrated formal document to be communicated to the patient. The healthcare team may also face other considerations such as record keeping and communication responsibilities when the patient (or the patient’s insurer) …


Acceptance And Commitment Therapist Views On The Sacred, Amal Abuzalaf Mull Aug 2015

Acceptance And Commitment Therapist Views On The Sacred, Amal Abuzalaf Mull

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

Spirituality and/or religion (S/R) continue to be an important topic in mental health treatment, especially regarding their relationship to a psychotherapist’s theoretical orientation and practice with clients. Given the increased relevance of spirituality to third-wave cognitive behavioral therapies, the current study explores the S/R of Acceptance and Commitment Therapy (ACT) psychotherapists and how their S/R is associated to their attitudes and behaviors within mental health and their use of ACT. Online surveys were administered, producing a sample of 97 ACT psychotherapists in the United States. Results indicated low levels of religiosity and high levels of spirituality among ACT psychotherapists in …


Human Trafficking & Commercial Sex Exploitation: Treatment Recommendations For An Invisible Population, Abigail K. Wolfe Aug 2015

Human Trafficking & Commercial Sex Exploitation: Treatment Recommendations For An Invisible Population, Abigail K. Wolfe

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

This article addresses the issue of human trafficking, also termed modern slavery, specifically focusing on the treatment of survivors of Commercial Sexual Exploitation (CSE). Treatment recommendations are made based on a trauma-focused, relational model aimed at reinstating psychological well-being in the survivor. This article reviews the literature on three related bodies of research due to the absence of direct psychological literature. Literature on captivity, control and torture, literature on the treatment of refugees and asylum seekers, and literature on sexual abuse treatment for those who have been victimized through the sex trade. Additionally, practical aspects of human trafficking are discussed …


Atomic Structure Of Grk5 Reveals Distinct Structural Features Novel For G Protein-Coupled Receptor Kinases, Konstantin E. Komolov, Anshul Bhardwaj, Jeffrey L. Benovic Aug 2015

Atomic Structure Of Grk5 Reveals Distinct Structural Features Novel For G Protein-Coupled Receptor Kinases, Konstantin E. Komolov, Anshul Bhardwaj, Jeffrey L. Benovic

Department of Biochemistry and Molecular Biology Faculty Papers

G protein-coupled receptor kinases (GRKs) are members of the protein kinase A, G, and C families (AGC) and play a central role in mediating G protein-coupled receptor phosphorylation and desensitization. One member of the family, GRK5, has been implicated in several human pathologies, including heart failure, hypertension, cancer, diabetes, and Alzheimer disease. To gain mechanistic insight into GRK5 function, we determined a crystal structure of full-length human GRK5 at 1.8 Å resolution. GRK5 in complex with the ATP analog 5'-adenylyl β,γ-imidodiphosphate or the nucleoside sangivamycin crystallized as a monomer. The C-terminal tail (C-tail) of AGC kinase domains is a highly …


The C-Terminal Domain (Ctd) Of Human Dna Glycosylaseneil1 Is Required For Forming Berosome Repair Complex With Dna Replication Proteins At The Replicating Genome: Dominant Negative Function Of The Ctd, Pavana M. Hegde, Arijit Dutta, Shiladitya Sengupta, Joy Mitra, Sanjay Adhikari, Alan E. Tomkinson, Guo-Min Li, Istvan Boldogh, Tapas K. Hazra, Sankar Mitra, Muralidhar L. Hegde Aug 2015

The C-Terminal Domain (Ctd) Of Human Dna Glycosylaseneil1 Is Required For Forming Berosome Repair Complex With Dna Replication Proteins At The Replicating Genome: Dominant Negative Function Of The Ctd, Pavana M. Hegde, Arijit Dutta, Shiladitya Sengupta, Joy Mitra, Sanjay Adhikari, Alan E. Tomkinson, Guo-Min Li, Istvan Boldogh, Tapas K. Hazra, Sankar Mitra, Muralidhar L. Hegde

Toxicology and Cancer Biology Faculty Publications

The human DNA glycosylase NEIL1 was recently demonstrated to initiate prereplicative base excision repair (BER) of oxidized bases in the replicating genome, thus preventing mutagenic replication. A significant fraction of NEIL1 in cells is present in large cellular complexes containing DNA replication and other repair proteins, as shown by gel filtration. However, how the interaction of NEIL1 affects its recruitment to the replication site for prereplicative repair was not investigated. Here, we show that NEIL1 binarily interacts with the proliferating cell nuclear antigen clamp loader replication factor C, DNA polymerase δ, and DNA ligase I in the absence of DNA …


Pressure Ulcers, Annika Dow Bsn, Rn, Antoinette Morris Bsn, Rn, Kessiah Roland Bsn, Rn Aug 2015

Pressure Ulcers, Annika Dow Bsn, Rn, Antoinette Morris Bsn, Rn, Kessiah Roland Bsn, Rn

Patient Care Services / Nursing

No abstract provided.


A Quality Improvement Project To Increase Diabetes Self-Efficacy In A Rural Primary Care Clinic Through Patient Utilization Of A Diabetic Logbook, Margo D. Sutton Aug 2015

A Quality Improvement Project To Increase Diabetes Self-Efficacy In A Rural Primary Care Clinic Through Patient Utilization Of A Diabetic Logbook, Margo D. Sutton

Doctor of Nursing Practice (DNP) Projects

The prevalence of type 2 diabetes mellitus (T2DM) has increased substantially in the United States in recent years. Teaching self-management to diabetic patients is essential to help them control their chronic disease. Albert Bandura’s theory of self-efficacy is commonly used in chronic disease self-management programs and is the theoretical framework upon which this Doctor of Nursing Practice (DNP) pilot project was built.

This evidence-based change in practice project took place in a rural primary care clinic in the central valley of California, and involved the development of a diabetes logbook, which was a tool for patients to use to learn …


Oral Nutritional Supplements And Nursing Documentation, Seana Rivera Bsn, Rn, Rachel Tallarico Bsn, Rn, Cadena Wood Bsn, Rn Aug 2015

Oral Nutritional Supplements And Nursing Documentation, Seana Rivera Bsn, Rn, Rachel Tallarico Bsn, Rn, Cadena Wood Bsn, Rn

Patient Care Services / Nursing

No abstract provided.


Examining The Relationship Between Bicultural Stress, Mental Well-Being, Perceived Social Support, And Education Among People Of African Descent, Zemed Beraki Berhe Aug 2015

Examining The Relationship Between Bicultural Stress, Mental Well-Being, Perceived Social Support, And Education Among People Of African Descent, Zemed Beraki Berhe

Seton Hall University Dissertations and Theses (ETDs)

Studies investigating the bicultural experiences of people of African descent are significantly underrepresented in the literature. The primary purpose of this exploratory study was to examine the relationship between experiences of bicultural stress and mental well-being. In investigating this relationship, perceived social support and education were examined as protective factors, and its relationship to bicultural stress for this population. With the ultimate goal of this information contributing to the understanding of bicultural processes within this population and the relationship to mental health outcomes. A non-experimental (non-randomized) research design was utilized to examine the study research questions and hypotheses. The participants …


Risques À La Sst : Les Stratégies Mises En Œuvre Par Des Adolescents Apprentis En Métier Semi-Spécialisé Lors D’Évènements Imprévus, Marie Laberge, Aurélie Tondoux, Bénédicte Calvet, Dolores Bayard, Curtis Breslin Aug 2015

Risques À La Sst : Les Stratégies Mises En Œuvre Par Des Adolescents Apprentis En Métier Semi-Spécialisé Lors D’Évènements Imprévus, Marie Laberge, Aurélie Tondoux, Bénédicte Calvet, Dolores Bayard, Curtis Breslin

Rapports de recherche scientifique

Plusieurs études ont montré qu’une faible expérience en emploi, souvent caractéristique des très jeunes travailleurs, était associée à une augmentation du risque de subir une lésion professionnelle. Parmi les jeunes travailleurs, les plus susceptibles de se blesser au travail sont ceux qui ont quitté l’école sans diplôme d’études secondaires, ceux qui occupent des emplois manuels ainsi que ceux qui éprouvent des difficultés d’apprentissage objectivées. Le ministère de l’Éducation, du Loisir et du Sport (MELS) a mis sur pied en 2007-2008 la Formation menant à l’exercice d’un métier semi-spécialisé (FMS), qui s’adresse justement à ces jeunes considérés plus à …


Patient Rounding, Emilie Fox Bsn, Rn, Nicole Quarantana Bsn, Rn, Kiley Robinson Bsn, Rn, Vanessa Spamer Bsn, Rn Aug 2015

Patient Rounding, Emilie Fox Bsn, Rn, Nicole Quarantana Bsn, Rn, Kiley Robinson Bsn, Rn, Vanessa Spamer Bsn, Rn

Patient Care Services / Nursing

No abstract provided.


Nurse-Controlled Analgesia, Courtney Bloss Bsn, Rn, Alyssa Boyd Bsn, Rn, Kristen Halenar Bsn, Rn Aug 2015

Nurse-Controlled Analgesia, Courtney Bloss Bsn, Rn, Alyssa Boyd Bsn, Rn, Kristen Halenar Bsn, Rn

Patient Care Services / Nursing

No abstract provided.


Managing Nas Scores With Non-Pharmacological Measures, Katie Gehringer Bsn, Rn, Jessica Weiss Bsn, Rn Aug 2015

Managing Nas Scores With Non-Pharmacological Measures, Katie Gehringer Bsn, Rn, Jessica Weiss Bsn, Rn

Patient Care Services / Nursing

No abstract provided.


The High Risk Hospitalized Antepartum Patient Project, Janice Bartolai Bsn, Rn, Alyssa Hischak Bsn, Rn Aug 2015

The High Risk Hospitalized Antepartum Patient Project, Janice Bartolai Bsn, Rn, Alyssa Hischak Bsn, Rn

Patient Care Services / Nursing

No abstract provided.


Improving Staff Knowledge Of Their Patients' Fall Risk Through The Use Of Visual Tools, Shannon King Bsn, Rn, Tina Marsteller Bsn, Rn, Courtney Sniscak Bsn, Rn, Maria Zarzecki Bsn, Rn Aug 2015

Improving Staff Knowledge Of Their Patients' Fall Risk Through The Use Of Visual Tools, Shannon King Bsn, Rn, Tina Marsteller Bsn, Rn, Courtney Sniscak Bsn, Rn, Maria Zarzecki Bsn, Rn

Patient Care Services / Nursing

No abstract provided.


Narrative Journaling In Conjunction With "Tales From The Bedside" During The Nurse Residency Program, Katherine Filemyr Bsn, Rn, Kerry Merkel Bsn, Rn, Jeanette Ward Bsn, Rn Aug 2015

Narrative Journaling In Conjunction With "Tales From The Bedside" During The Nurse Residency Program, Katherine Filemyr Bsn, Rn, Kerry Merkel Bsn, Rn, Jeanette Ward Bsn, Rn

Patient Care Services / Nursing

No abstract provided.


Improving The Timing Of Insulin Administration, Jessica Buzinski Bsn, Rn, Anna E. Dixon Rn, Bsn, Renelle L. Stauffer Rn, Msn, Bsn Aug 2015

Improving The Timing Of Insulin Administration, Jessica Buzinski Bsn, Rn, Anna E. Dixon Rn, Bsn, Renelle L. Stauffer Rn, Msn, Bsn

Patient Care Services / Nursing

No abstract provided.


Nanotechnology In The Real World: Redeveloping The Nanomaterial Consumer Products Inventory, Marina E. Vance, Todd Kuiken, Eric P. Vejerano, Sean P. Mcginnis, Michael F. Hochella Jr., David Rejeski, Matthew S. Hull Aug 2015

Nanotechnology In The Real World: Redeveloping The Nanomaterial Consumer Products Inventory, Marina E. Vance, Todd Kuiken, Eric P. Vejerano, Sean P. Mcginnis, Michael F. Hochella Jr., David Rejeski, Matthew S. Hull

Faculty Publications

To document the marketing and distribution of nano-enabled products into the commercial marketplace, the Woodrow Wilson International Center for Scholars and the Project on Emerging Nanotechnologies created the Nanotechnology Consumer Products Inventory (CPI) in 2005. The objective of this present work is to redevelop the CPI by leading a research effort to increase the usefulness and reliability of this inventory. We created eight new descriptors for consumer products, including information pertaining to the nanomaterials contained in each product. The project was motivated by the recognition that a diverse group of stakeholders from academia, industry, and state/federal government had become highly …


Impact Of Adverse Childhood Experiences On Intimate Partner Violence Perpetration Among Sri Lankan Men, Ruvani W. Fonseka, Alexandra M. Minnis, Anu Manchikanti Gomez Aug 2015

Impact Of Adverse Childhood Experiences On Intimate Partner Violence Perpetration Among Sri Lankan Men, Ruvani W. Fonseka, Alexandra M. Minnis, Anu Manchikanti Gomez

Faculty Research, Scholarly, and Creative Activity

In Sri Lanka, over one in three women experience intimate partner violence (IPV) victimization in their lifetime, making it a serious public health concern. Adverse childhood experiences (ACEs) such as child abuse and neglect, witnessing domestic violence, parental separation, and bullying are also widespread. Studies in Western settings have shown positive associations between ACEs and IPV perpetration in adulthood, but few have examined this relationship in a non-Western context. In the present study, we examined the association of ACEs with IPV perpetration among Sri Lankan men surveyed for the UN Multi-Country Study on Men and Violence in Asia and the …


Neuroimmune And Neuropathic Responses Of Spinal Cord And Dorsal Root Ganglia In Middle Age, William Galbavy, Martin Kaczocha, Michelino Puopolo, Mario Rebecchi Aug 2015

Neuroimmune And Neuropathic Responses Of Spinal Cord And Dorsal Root Ganglia In Middle Age, William Galbavy, Martin Kaczocha, Michelino Puopolo, Mario Rebecchi

Department of Anesthesiology Faculty Publications

Prior studies of aging and neuropathic injury have focused on senescent animals compared to young adults, while changes in middle age, particularly in the dorsal root ganglia (DRG), have remained largely unexplored. 14 neuroimmune mRNA markers, previously associated with peripheral nerve injury, were measured in multiplex assays of lumbar spinal cord (LSC), and DRG from young and middle-aged (3, 17 month) naïve rats, or from rats subjected to chronic constriction injury (CCI) of the sciatic nerve (after 7 days), or from aged-matched sham controls. Results showed that CD2, CD3e, CD68, CD45, TNF-α, IL6, CCL2, ATF3 and TGFβ1 mRNA levels were …


Differential Host Immune Responses After Infection With Wild-Type Or Lab-Attenuated Rabies Viruses In Dogs., Clement W Gnanadurai, Yang Yang, Ying Huang, Zhenguang Li, Christina M Leyson, Tanya L Cooper, Simon R Platt, Stephen B Harvey, D Craig Hooper, Milosz Faber, Zhen F Fu Aug 2015

Differential Host Immune Responses After Infection With Wild-Type Or Lab-Attenuated Rabies Viruses In Dogs., Clement W Gnanadurai, Yang Yang, Ying Huang, Zhenguang Li, Christina M Leyson, Tanya L Cooper, Simon R Platt, Stephen B Harvey, D Craig Hooper, Milosz Faber, Zhen F Fu

Department of Medical Genetics Faculty Papers

METHODOLOGY/PRINCIPAL FINDINGS: The experimental infection of dogs with TriGAS induced high levels of VNA in the serum, whereas wt RABV infection did not. Dogs infected with TriGAS developed antibodies against the virus including its glycoprotein, whereas dogs infected with DRV-NG11 only developed rabies antibodies that are presumably specific for the nucleoprotein, (N) and not the glycoprotein (G). We show that infection with TriGAS induces early activation of B cells in the draining lymph nodes and persistent activation of DCs and B cells in the blood. On the other hand, infection with DRV-NG11 fails to induce the activation of DCs and …


Locomotor Adaptation Is Influenced By The Interaction Between Perturbation And Baseline Asymmetry After Stroke., Christine M. Tyrell, Erin Helm, Darcy S. Reisman Aug 2015

Locomotor Adaptation Is Influenced By The Interaction Between Perturbation And Baseline Asymmetry After Stroke., Christine M. Tyrell, Erin Helm, Darcy S. Reisman

Department of Physical Therapy Faculty Papers

Stroke survivors without cerebellar involvement retain the ability to adapt to the split-belt treadmill; however it has been suggested that their rate of adaptation may be slowed compared to those who are neurologically intact. Depending on limb placement, the split-belt treadmill can be configured to either exaggerate baseline asymmetry, or reduce it, which may affect the behavior of adaptation or de-adaptation. The objectives of this study were to characterize the rate and magnitude of locomotor (de)adaptation in chronic stroke survivors compared to healthy matched subjects, and to evaluate whether exaggeration or reduction of baseline asymmetry impact the responses. Seventeen stroke …


How Has The Affordable Care Act Benefitted Medically Underserved Communities? : National Findings From The 2014 Community Health Centers Uniform Data System, Jessica Sharac, Peter Shin, Sara J. Rosenbaum Aug 2015

How Has The Affordable Care Act Benefitted Medically Underserved Communities? : National Findings From The 2014 Community Health Centers Uniform Data System, Jessica Sharac, Peter Shin, Sara J. Rosenbaum

Geiger Gibson/RCHN Community Health Foundation Research Collaborative

Community health centers represent the single largest comprehensive primary health care system serving medically underserved communities, operating in more than 9,000 urban and rural locations. Newly-released data for 2014 from the Uniform Data System (UDS; the federal health center reporting system) shed important light on the impact of the Affordable Care Act in its first full year of implementation in medically underserved urban and rural communities across the U.S. These communities experience elevated poverty, heightened health risks, lack of access to primary health care, and a significantly greater likelihood that residents will be uninsured.

The UDS data show the ACA’s …


Workload Perceptions Of Pharmacists: Part Of Changing A National Trend, Fadi M. Alkhateeb, Omar F. Attarabeen, David Latif, Rachel Deliere Aug 2015

Workload Perceptions Of Pharmacists: Part Of Changing A National Trend, Fadi M. Alkhateeb, Omar F. Attarabeen, David Latif, Rachel Deliere

Pharmacy Practice & Administration

Background: A National Pharmacist Workforce Survey (NPW) survey is being conducted in the US every five years. The 2009- NPW project surveyed 1,391 participants, of which only 12 participants were from West Virginia. Therefore, such a small representation of West Virginian pharmacists may question the validity of extrapolating the results of the 2009 NPW survey to pharmacists in this state. As a result, a separate survey was needed to answer the questions about the perceived workload, work characteristics, and demographics for West Virginian pharmacists.

Objectives: The primary objective of this investigation was to identify the pharmacists’ perceptions of workload in …


Acidic And Basic Destruction Of Tissues, Cydney Eaton Aug 2015

Acidic And Basic Destruction Of Tissues, Cydney Eaton

University Honors Program

A coroner’s case I had learned about involved a man attempting to dispose of a body with acid. Shortly after exposure, the man was apprehended and the body was located. Upon investigation, police force determined the acid used to be hydrochloric acid, however, exact concentration remains unknown (Kohr, 2010). This led to the question of which easily accessible acid works best to degrade tissue. To answer this, an experiment was conducted involving pig feet and various concentrations of common acids and a single strong base. The feet were submerged in the solutions overnight and mass percent lost or gained was …


Targeted Salivary Biomarkers For Discrimination Of Periodontal Health And Disease(S), Jeffrey L. Ebersole, Radhakrishnan Nagarajan, David Akers, Craig S. Miller Aug 2015

Targeted Salivary Biomarkers For Discrimination Of Periodontal Health And Disease(S), Jeffrey L. Ebersole, Radhakrishnan Nagarajan, David Akers, Craig S. Miller

Center for Oral Health Research Faculty Publications

Generally, clinical parameters are used in dental practice for periodontal disease, yet several drawbacks exist with the clinical standards for addressing the needs of the public at large in determining the current status/progression of the disease, and requiring a significant amount of damage before these parameters can document disease. Therefore, a quick, easy and reliable method of assessing and monitoring periodontal disease should provide important diagnostic information that improves and speeds treatment decisions and moves the field closer to individualized point-of-care diagnostics.

OBJECTIVE: This report provides results for a saliva-based diagnostic approach for periodontal health and disease based upon …


Designing For Practice Development In A Social Learning System: Communicating Norms And Vicarious Experience, Claire Loe Aug 2015

Designing For Practice Development In A Social Learning System: Communicating Norms And Vicarious Experience, Claire Loe

Dissertations and Theses (Open Access)

Over the past quarter century, the United States has experienced an increase in demand for health services. Expanded use of community health workers (CHWs) has been identified as a strategic response for more effective distribution of healthcare resources by alleviating pressures on clinical personnel and infusing prevention education into the community-to-clinical care continuum. Expansion of the CHW workforce poses many challenges. For CHWs to effectively reduce costs and pressures on the healthcare system, ‘expansion’ implies not only increasing their numbers, but also assuring a workforce that has the capacity to perform in diverse settings. I propose a theoretical framework for …


Improving Child Survival Through A District Management Strengthening And Community Empowerment Intervention: Early Implementation Experiences From Uganda., Anne R. Katahoire, Dorcus K. Henriksson, Eric Ssegujja, Peter Waiswa, Florence Ayebare, Danstan Bagenda, Anthony K. Mbonye, Stefan S. Peterson Aug 2015

Improving Child Survival Through A District Management Strengthening And Community Empowerment Intervention: Early Implementation Experiences From Uganda., Anne R. Katahoire, Dorcus K. Henriksson, Eric Ssegujja, Peter Waiswa, Florence Ayebare, Danstan Bagenda, Anthony K. Mbonye, Stefan S. Peterson

Journal Articles: Epidemiology

BACKGROUND: The Community and District Empowerment for Scale-up (CODES) project pioneered the implementation of a comprehensive district management and community empowerment intervention in five districts in Uganda. In order to improve effective coverage and quality of child survival interventions CODES combines UNICEF tools designed to systematize priority setting, allocation of resources and problem solving with Community dialogues based on Citizen Report Cards and U-Reports used to engage and empower communities in monitoring health service provision and to demand for quality services. This paper presents early implementation experiences in five pilot districts and lessons learnt during the first 2 years of …


Application Of Ichip To Grow “Uncultivable” Microorganisms And Its Impact On Antibiotic Discovery, Rinzhin T. Sherpa, Caretta J. Reese, Hamidreza Montazeri Aliabadi Aug 2015

Application Of Ichip To Grow “Uncultivable” Microorganisms And Its Impact On Antibiotic Discovery, Rinzhin T. Sherpa, Caretta J. Reese, Hamidreza Montazeri Aliabadi

Pharmacy Faculty Articles and Research

Purpose. Antibiotics have revolutionized modern medicine, allowing significant progress in healthcare and improvement in life expectancy. Development of antibiotic resistance by pathogenic bacteria is a natural phenomenon; however, the rate of antibiotic resistance emergence is increasing at an alarming rate, due to indiscriminate use of antibiotics in healthcare, agriculture and even everyday products. Traditionally, antibiotic discovery has been conducted by screening extracts of microorganisms for antimicrobial activity. However, this conventional source has been over-used to such an extent that it poses the risk of “running out” of new antibiotics. Aiming to increase access to a greater diversity of microorganisms, …