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2015

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Articles 11011 - 11040 of 11981

Full-Text Articles in Medicine and Health Sciences

A Study Of The Relationship Between Nasion Perpendicular And The True Vertical Line, Jeffrey Shelley Jan 2015

A Study Of The Relationship Between Nasion Perpendicular And The True Vertical Line, Jeffrey Shelley

All ETDs from UAB

A STUDY OF THE RELATIONSHIP BETWEEN NASION PERPENDICULAR AND THE TRUE VERTICAL LINE JEFFREY ALBERT SHELLEY JR. DEPARTMENT OF ORTHODONTICS ABSTRACT The purpose of this study is to assess the relationship between Nasion perpendicular and the true vertical line between patient groups using cephalometric analysis. Materials and Methods: Ninety-six adolescent patients comprised the sample for this study. Subjects were between 10 and 18 years old, with no major craniofacial deformity. Three groups of patients were divided in to three groups (Class I, Class II and Class III) based on their skeletal antero-posterior relationship. Pre-treatment lateral cephalometric radiographs were taken with …

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The Unfolded Protein Response And Calcium Dysregulation In Autosomal Dominant Retinitis Pigmentosa Animal Models., Vishal Madhukar Shinde Jan 2015

The Unfolded Protein Response And Calcium Dysregulation In Autosomal Dominant Retinitis Pigmentosa Animal Models., Vishal Madhukar Shinde

All ETDs from UAB

The photoreceptor cell death in autosomal dominant retinitis pigmentosa (ADRP) is associated with molecular changes that occur due to mutations in a specific gene. S334ter RHO and P23H RHO are two ADRP rat models expressing mutant rhodopsin. The unfolded protein response (UPR) is a cellular stress response involved in the pathophysiology of several retinal disorders including P23H RHO rats. Considering our previous findings, we started our investigation by examining the status of UPR in S334ter RHO rats. As UPR tightly regulates several signaling pathways, we further studied whether UPR activation in S334ter and P23H RHO retina is accompanied by the …

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The Multifactorial Roles Of The Cytokines Il-21 And Il-22 In Mediating Host Defense Against Enteropathogenic Infection, Daniel James Silberger Jan 2015

The Multifactorial Roles Of The Cytokines Il-21 And Il-22 In Mediating Host Defense Against Enteropathogenic Infection, Daniel James Silberger

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Enteropathogenic strains of Escherichia coli are a major public health concern, causing diarrhea and mortality particularly among infants and children in developing countries. Citrobacter rodentium is a murine intestinal pathogen that models pathogenic E. coli infection. Both innate and adaptive immune cells contribute to the clearance of C. rodentium. In particular, B cells and CD4+ T cells but not CD8+ T cells are required for protection during a primary infection with C. rodentium. In addition, T cell-dependent antibody responses are required for clearance. Th17 cells are a major CD4+ T cell population that accumulates in the large intestine during C. …

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An Examination Of Farm-To-Consumer Retail Outlet Usage Among Participants Of The Special Supplemental Nutrition Program For Women, Infants, And Children (Wic) In Birmingham, Al, Chelsea Renee Singleton Jan 2015

An Examination Of Farm-To-Consumer Retail Outlet Usage Among Participants Of The Special Supplemental Nutrition Program For Women, Infants, And Children (Wic) In Birmingham, Al, Chelsea Renee Singleton

All ETDs from UAB

Disparities in the neighborhood retail food environment have been hypothesized to be associated with poor diet quality and adverse health outcomes such as obesity. Studies have found that lower income communities often have reduced access to affordable healthy foods. In 2009, the Centers for Disease Control and Prevention proposed direct farm-to-consumer (FTC) retail outlets (i.e. farmers markets, farm/roadside stands, community gardens and community supported agriculture programs) as a potential strategy to alleviate retail food environment disparities in communities with limited resources. Information on the behavioral and health implications of FTC outlet usage by lower income individuals is limited. This research …

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Bidirectional Interference Between Speech And Nonspeech Tasks In Younger, Middle-Aged, And Older Adults, Christopher Dromey, Dallin J. Bailey Jan 2015

Bidirectional Interference Between Speech And Nonspeech Tasks In Younger, Middle-Aged, And Older Adults, Christopher Dromey, Dallin J. Bailey

Faculty Publications

Purpose: The purpose of this study was to examine divided attention over a large age range by looking at the effects of 3 nonspeech tasks on concurrent speech motor performance. The nonspeech tasks were designed to facilitate measurement of bidirectional interference, allowing examination of their sensitivity to speech activity. A cross-sectional design was selected to explore possible changes in divided-attention effects associated with age. Method: Sixty healthy participants were separated into3 groups of 20: younger (20s), middle-aged (40s), and older (60s) adults. Each participant completed a speech task (sentence repetitions) once in isolation and once concurrently with each of 3 …

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The Effects Of Emotional Expression On Vibrato, Christopher Dromey, Sharee O. Holmes, J Arden Hopkin, Kristine Tanner Jan 2015

The Effects Of Emotional Expression On Vibrato, Christopher Dromey, Sharee O. Holmes, J Arden Hopkin, Kristine Tanner

Faculty Publications

Summary: Objectives/Hypothesis. The purpose of this study was to investigate the effect of emotional expression on several acoustic measures of vibrato, including its rate, extent, and steadiness. We hypothesized that singing a passage with emotional content would influence these variables. Study Design. This study used a within-subjects, repeated-measures design. Singer performance under different conditions was analyzed. Methods. Ten graduate student singers (eight women, two men) completed a series of tasks including sustained sung vowels at several pitch and loudness levels, an assigned song that was judged to have relatively neutral emotion, and a personal selection that included passages of intense …

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Developmental Surveillance And Referral In A Traditionally Medically Underserved Border Community, Eugenia C. Gonzalez, Connie Summers, Vannesa Mueller, Anne Hernandez, Gilda Gil-Lopez, Danielle C. Garcia, Maritza E. Lopez Jan 2015

Developmental Surveillance And Referral In A Traditionally Medically Underserved Border Community, Eugenia C. Gonzalez, Connie Summers, Vannesa Mueller, Anne Hernandez, Gilda Gil-Lopez, Danielle C. Garcia, Maritza E. Lopez

Faculty Publications

Purpose Early identification and referral have been shown to improve long-term outcomes for children with disabilities. However, the number of children enrolled in early intervention services continues to be lower than the number of children confirmed to be developmentally delayed later in life. This study investigated the pattern of developmental surveillance and referral practices of pediatricians in a traditionally medically underserved border community. Description An online survey was created by members of a community/academic partnership. Emails were followed up with a personal contact to doctor’s offices to increase the response rate. Assessment Response rate for the survey was 26.7 %. …

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Obesity Weighs Down Memory: Emerging Insights Into The Epigentic Basis Of Obesity-Induced Memory Impairment In Adult Mice, Frankie Darryn Heyward Jan 2015

Obesity Weighs Down Memory: Emerging Insights Into The Epigentic Basis Of Obesity-Induced Memory Impairment In Adult Mice, Frankie Darryn Heyward

All ETDs from UAB

A preponderance of evidence has established that obesity contributes to memory impairments in mid-age adults. Empirical evidence has revealed that diet-induced obesity contributes to memory impairments in adult rodents. Precisely how obesity disrupts memory remains an open question. Bourgeoning data indicate that molecular epigenetic mechanisms mediate the changes in gene transcription that are necessary for hippocampus-dependent memory consolidation. Epigenetic mechanisms, such as DNA methylation, stably regulate gene expression without affecting the DNA sequence. Moreover, DNA methylation of memory-related genes with in the hippocampus is indispensible for memory formation. There is recent evidence of obesity-induced aberrantions in DNA methylation both peripherally …

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Caenorhabditis Elegans Sperm Chemotaxis, Hieu Dinh Hoang Jan 2015

Caenorhabditis Elegans Sperm Chemotaxis, Hieu Dinh Hoang

All ETDs from UAB

Survival of animal species depends on fertilization, the union of an egg and a sperm. The sperm's ability to find an egg quickly allows it to pass on male genetic material. It is challenging to record sperm targeting or guidance efficiency and motility in utero. We use the Caenorhabditis elegans model organism to study sperm guidance, primarily because its epidermis is transparent, allowing the observation of live fluorescent sperm in the hermaphrodite uterus. Using genome-editing techniques, genetic analyses, fluorescent microscopy, and mass spectrometry, we aim to address the following two questions: how hermaphrodites regulate sperm motility in the uterus, and …

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Statistical Methodology To Improve The Understanding Of Dna Methylation Data, Lindsay Leigh Waite Jones Jan 2015

Statistical Methodology To Improve The Understanding Of Dna Methylation Data, Lindsay Leigh Waite Jones

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The study of epigenetics involves the investigation of genomic elements that do not directly affect DNA sequence but are stable and preserved during cell division. One of the most commonly studied epigenetic elements is DNA methylation, which occurs when a methyl group is added to a cytosine residue in the DNA sequence. The advancement of technology to quantify DNA methylation, including bisulfite sequencing and bisulfite microarrays, has led to a large amount of available data. However, many questions still remain as to how to statistically analyze this data. This dissertation addresses some statistical concerns related to the analysis of DNA …

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Robust Production Of Mature Ribosomal Rna Is Directly Influenced By Multiple Steps Within The Transcription Cycle, Krysta Engel Jan 2015

Robust Production Of Mature Ribosomal Rna Is Directly Influenced By Multiple Steps Within The Transcription Cycle, Krysta Engel

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Cellular growth depends on the capacity for protein synthesis, and likewise ribosome biogenesis. Therefore, robust rRNA synthesis by RNA Polymerase I (Pol I) is a critical component of cell growth. The work reported in this dissertation highlights the contribution of polymerase domains and trans-acting proteins during rRNA synthesis and ribosome biogenesis. Eukaryotes utilize three homologous nuclear RNA polymerases (RNAPs) to express their genomes. The trigger loop (TL) is a well conserved region within the active site of multi-subunit RNAPs that plays a direct role during the nucleotide addition cycle. Analysis of Pol II TL mutants has suggested that catalysis is …

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Translucency, Stain Resistance And Hardness Of Composites Used For Invisalign Attachments, Katelyn Bowman Feinberg Jan 2015

Translucency, Stain Resistance And Hardness Of Composites Used For Invisalign Attachments, Katelyn Bowman Feinberg

All ETDs from UAB

The purpose of this study is to compare the translucency parameter, stain resistance and hardness of dental restorative composites and orthodontic adhesives in order to determine an ideal esthetic attachment material for Invisalign® treatment. Materials and Methods: Two dental restorative composites (Filtek™ Supreme Ultra, Tetric EvoCeram®) and three orthodontic adhesives (L.C.R.™, Transbond™ XT, Phase II® Dual Cure) were used in this in-vitro study. 2.0 mm thick samples of each material were fabricated in silicone molds covered with a flat sheet of Invisalign attachment template material. To evaluate the translucency parameter and stain resistance, initial L*a*b* values of each material were …

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Metabolic And Oxidative Regulation Of Neuronal Autophagy And Survival, Matthew Dodson Jan 2015

Metabolic And Oxidative Regulation Of Neuronal Autophagy And Survival, Matthew Dodson

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Neurodegenerative diseases, such as Parkinson's disease, Alzheimer's disease and Huntington's disease are all characterized by metabolic dysfunction, increased oxidative damage to proteins and organelles, formation of proteinaceous inclusions, decreased autophagic and proteasomal function, and eventual neuronal and glial cell death. While our understanding of the mechanisms that underlie many of these pathologies is constantly growing, their exact cause, onset, interplay and progression still remain unclear. The gap between the description of disease pathologies and understanding the fundamental mechanisms of disease pathogenesis, progression and potential therapeutics to mitigate disease progression is still large. Based on the observation that altered glucose utilization, …

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The Characterization Of Human Cytosolic Sulfotransferase 1a1: Interactions With 17Α-Ethinylestradiol, Katie Jo Glowacki Jan 2015

The Characterization Of Human Cytosolic Sulfotransferase 1a1: Interactions With 17Α-Ethinylestradiol, Katie Jo Glowacki

All ETDs from UAB

Human cytosolic sulfotransferases (SULTs) are a family of Phase II conjugating enzymes that facilitate the transfer of a sulfonate moiety from 3’phosphoadenosine 5’phosphosulfate (PAPS) to hydroxyl or amine groups of acceptor substrates. SULT1A1, located in many tissues throughout the human body including the liver, is important in the metabolism of many endogenous, exogenous, xenobiotic, and drug compounds. The majority of substrates for SULT1A1 are small neutral phenols including 1-naphthol and acetaminophen; however, SULT1A1 sulfates larger compounds including 17β-estradiol (E2) and raloxifene. SULT1A1 conjugates E2 with a Km of 2.3 µM and the structure of E2 is almost identical to the …

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Regulation Of The Regulatory T Cell-Immunoglobulin A Pathway, Katie Lynn Alexander Jan 2015

Regulation Of The Regulatory T Cell-Immunoglobulin A Pathway, Katie Lynn Alexander

All ETDs from UAB

A dysregulated immune response to the microbiota is a defined characteristic of Crohn's Disease (CD), a type of Inflammatory Bowel Disease (IBD). Understanding how homeo-stasis is maintained in the intestine despite the immense concentration of bacteria present is an active area of research. Regulatory T cells (Tregs) play an important role in mucosal tolerance by controlling inflammation and modulating immune responses initiated by T effector cells (Teffs). Tregs also provide vital survival factors to IgA+ B cells in the intes-tine in order to support Immunoglobulin A (IgA) responses as part of a protective Treg-IgA pathway, which functions to maintain mutualism …

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Bioenergetics As A Biomarker Of Health And Disease, Philip Kramer Jan 2015

Bioenergetics As A Biomarker Of Health And Disease, Philip Kramer

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The increasing prevalence of metabolic syndrome, diabetes, atherosclerosis, and many other diseases only recently associated with aberrant metabolism, have led to a de-mand for clinical assays to determine a patient’s mitochondrial health. With the rapidly growing interest in personalized medicine, such an assay would ideally be able to capture the metabolic changes associated with oxidative stress, inflammation, and therapy of a patient in a swift and non-invasive manner. Short of tissue biopsies, this burgeoning field of Translational Bioenergetics has had minimal success in obtaining sufficient human cells and the means to assess them both accurately and swiftly. The purpose of …

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Defining The Role Of Trps1 In Phosphate Mediated Mineralization, Maria Kuzynski Jan 2015

Defining The Role Of Trps1 In Phosphate Mediated Mineralization, Maria Kuzynski

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Mineralization is a tightly controlled bi-phasic process that occurs when crystals of calcium and phosphate (Pi) are laid down within the extracellular matrix. However, the molecular networks regulating the initiation and progression of this process have not been well characterized. Pi, as one of the components of mineral crystals and a signaling molecule that regulates expression of mineralization-related genes, is essential to the mineralization process. In our studies, we discovered a novel function for Pi in this process: Pi is sufficient to induce secretion of matrix vesicles, which support the initiation of mineralization. Furthermore, we determined that this induction is …

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Transferring Virtual Reality Training To Real World Settings In Individuals With Low Vision And Dual-Sensory Impairments, Ellen Lambert Bowman Jan 2015

Transferring Virtual Reality Training To Real World Settings In Individuals With Low Vision And Dual-Sensory Impairments, Ellen Lambert Bowman

All ETDs from UAB

TRANSFERRING VIRTUAL REALITY TRAINING TO REAL WORLD SETTINGS IN INDIVIDUALS WITH LOW VISION AND DUAL-SENSORY IMPAIRMENTS ELLEN LAMBERT BOWMAN VISION SCIENCE GRADUATE PROGRAM ABSTRACT The goal of this study was to determine if individuals with low vision could learn useful visual skills in Virtual Reality and could transfer these skills to the real world. To achieve this goal, one set of Orientation & Mobility (O&M) skills, using the near lane parallel traffic surge to decide the safest timing to cross a signal controlled street, was selected. Twelve participants with vision too poor to use pedestrian signals were randomly assigned to …

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Predictive Modeling Of Ocular Surface Disease States Using Multiple Inflammatory Biomarkers, John L. Bradley Jan 2015

Predictive Modeling Of Ocular Surface Disease States Using Multiple Inflammatory Biomarkers, John L. Bradley

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ABSTRACT Purpose The aim of this study was to adapt conjunctival impression cytology (CIC) and RNA isolation and processing procedures for gene expression analysis of ocular surface inflammatory biomarkers. The RNA yield and quality should be sufficient to enable quantitative real-time PCR of no less than 12 key target genes, with the goal of differentiating among dry eye groups. This study used the optimized inflammatory biomarker gene expression assay in a patient study to identify differences between dry eye and control participants. Materials and Methods CIC was used to collect conjunctival surface cells from 53 qualifying dry eye and control …

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Three-Dimensional Soft Tissue Analysis Of Facial Morphology Of A Colombian Population Compared To Adult Caucasians, Sonia Bravo-Hammett Jan 2015

Three-Dimensional Soft Tissue Analysis Of Facial Morphology Of A Colombian Population Compared To Adult Caucasians, Sonia Bravo-Hammett

All ETDs from UAB

Aim: The purpose of this study is to describe the facial morphology of a Colombian population with three-dimensional imaging; and comparing their facial morphology with the Caucasian to create a database for this ethnicity. Materials and Methods: The study included 170 subjects selected from the Valle University in Cali-Colombia; and 1346 Caucasian subjects selected from the Face-Base Data funded by the National Institute of Dental and Craniofacial Research. All images were taken on Natural Head Position and captured using a stereo-photogrammetric camera system (3dMDfaceTM); to obtain a three dimensional image of each patient. The subjects were between 19 to 31 …

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Development Of A Conceptual Framework For Pediatric Preparedness Healthcare Coalitions: A Pilot Study, Bryan K. Breland Jan 2015

Development Of A Conceptual Framework For Pediatric Preparedness Healthcare Coalitions: A Pilot Study, Bryan K. Breland

All ETDs from UAB

Natural or man-made disasters overwhelm the resources of a healthcare organization and strain or compromise the provision of medical services to rapidly expanding patient populations. Public and private healthcare organization routinely plan and exercise systems and responses intended to bolster medical care capabilities and increase the capacity of the organization during crisis events. Providers of pediatric emergency medical service are particularly vulnerable to disaster surge, since many pediatric emergency services operate consistently at near capacity. In recent years, policy-makers and medical professionals have begun to look toward healthcare coalitions as a mechanism to rapidly expand resources and capacity for patient …

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The Alpha-Glucosidase Inhibitor Acarbose As A Calorie Restriction Mimetic To Modify Metabolic Outcomes In Mice, Rachel Ann Brewer Jan 2015

The Alpha-Glucosidase Inhibitor Acarbose As A Calorie Restriction Mimetic To Modify Metabolic Outcomes In Mice, Rachel Ann Brewer

All ETDs from UAB

Age-related diseases continue to be a leading cause of death. One of the only replicable methods proven to decrease age-related morbidity and mortality in multiple species is calorie restriction (CR). CR is difficult for human populations to implement, and has a number of associated risks and side effects. A CR mimetic could provide the healthspan- and lifespan-extending benefits of CR without the limitations. Acarbose (ACA), an α-glucosidase and α-amylase inhibitor approved to treat type 2 diabetes in humans, was recently identified as able to extend lifespan in healthy mice. The purpose of this research was to determine the effects of …

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Preparation Of Zirconia For Bonding Following Salivary Contamination, Pattarika Angkasith Jan 2015

Preparation Of Zirconia For Bonding Following Salivary Contamination, Pattarika Angkasith

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Purpose: To determine the best method of cleaning saliva-contaminated zirconia in order to regain its bond strength. Methods: Flat blocks of zirconia were particle-abraded with aluminum oxide and divided into eight groups (n=10). Groups 1-5 were first treated with 1 coat of an MDP-primer (Z-Prime Plus, Bisco) and groups 5-8 were left untreated. All specimens were contaminated with human saliva for 3 minutes other than the control (group 1). The specimens were then cleaned by rinsing with water for 20 sec (groups 2 and 5), cleaning with 35% phosphoric acid for 20 sec and rinsing (group 3 and 6), cleaning …

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Transient-State Kinetic Analysis Of The Rna Polymerase I Nucleotide Incorporation Mechanism, Francis Dean Appling Jan 2015

Transient-State Kinetic Analysis Of The Rna Polymerase I Nucleotide Incorporation Mechanism, Francis Dean Appling

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The diversity of enzymes and the reactions which they catalyze is enormous. Careful study of enzymatic reaction mechanisms has taught us a great deal about chemical reactivity and has given us insight into the chemical and physical basis of life. One particularly ubiquitous class of enzymes, the RNA polymerases, are expressed in all forms of life. RNA polymerases are central components of nucleic acid metabolism and display a variety of distinctive enzymatic features; two points which solicit their thorough study. The central theme of this dissertation is the use of kinetic techniques to describe enzymatic reaction mechanisms. Although the main …

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Transcriptional Regulation Of The Human Ribosomal Rna Gene, Blake L. Atwood Jan 2015

Transcriptional Regulation Of The Human Ribosomal Rna Gene, Blake L. Atwood

All ETDs from UAB

The ribosome has the major role of synthesizing almost all the proteins of the cell. One of the main structural components of the ribosome are the ribosomal RNAs 18S, 28S, 5.8S and the 5S which are bound by numerous proteins to make up a fully functional unit. In the human genome there are approximately 400 copies of the rRNA gene, which contains all but the 5S rRNA in one long transcription unit. This gene is found in tandem repeats on the acrocentric arm of chromosomes 13, 14, 15, 21 and 22. It is critical that this gene is tightly regulated …

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The I507-Atc→Att Silent Codon Change Contributes To The Misfolding Of ∆F508 Cftr, Vedrana Bali Jan 2015

The I507-Atc→Att Silent Codon Change Contributes To The Misfolding Of ∆F508 Cftr, Vedrana Bali

All ETDs from UAB

Synonymous codon changes (SCCs) do not alter the amino acid sequence of proteins, but may significantly change the phenotype. The frequency of synonymous codons is species- and gene-specific, described as codon usage bias (CUB). Over the past 50 years, research has shown that SCCs affect protein biogenesis, development of human disorders and the function of recombinant proteins developed for therapeutic applications. However, the molecular mechanisms by which SCCs alter the function of gene products are not completely understood. In Chapter 2 we summarize present knowledge in this field. The most common cause of cystic fibrosis (CF) is the deletion of …

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In- Vitro Wear Of Four Cad-Cam Materials In The Uab Wear Simulating Device, Ritika Bansal Jan 2015

In- Vitro Wear Of Four Cad-Cam Materials In The Uab Wear Simulating Device, Ritika Bansal

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In- vitro Wear of Four CAD- CAM Materials in the UAB Wear Simulating Device RITIKA BANSAL MS IN CLINICAL DENTISTRY ABSTRACT Hybrid ceramic/polymer blocks represent a new category of CAD/CAM materials that do not require heat treatment following milled fabrication and limited clinically relevant mechanical properties of these materials are available. Purpose: This study measures the hardness, flexural strength, modulus, and wear of 3 ceramic/polymer hybrid materials (LAVA Ultimate, Enamic, and Cerasmart), 2 reference glass ceramics (IPS e.max and Celtra Duo), and 1 reference composite material (Paradigm MZ100). Methods: Flexural strength specimens (n=10) (2.5 × 2.5 × 16 mm) were …

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An Analysis Of Selecting Personal Protective Equipment Clothing Used In Foundries, Quachel Bazile Jan 2015

An Analysis Of Selecting Personal Protective Equipment Clothing Used In Foundries, Quachel Bazile

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A foundry is a type of factory that deals with producing metal casting. The metals are casted in to shape by being melted into liquid and is then poured into the mold. Personal protective equipment (PPE) is worn to protect the worker from the hazard that engineering control cannot protect the worker from. A Private company wanted to evaluate their current PPE clothing to understand how well they protect a worker against molten metal splash PPE clothing was tested using the American Standard for Testing Material (ASTM) standard F955-07 entitled "Evaluating Heat Transfer through Materials for Protective Clothing upon Contact …

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Modulation Of The Unfolded Protein Response To Delay Apoptosis In An Autosomal Dominant Retinitis Pigmentosa Animal Model, Yogesh Bhootada Jan 2015

Modulation Of The Unfolded Protein Response To Delay Apoptosis In An Autosomal Dominant Retinitis Pigmentosa Animal Model, Yogesh Bhootada

All ETDs from UAB

Retinitis pigmentosa (RP) is a group of retinal degenerative diseases characterized by the loss of rod photoreceptor cells that can be followed by cone degeneration eventually culminating in total photoreceptor cell loss. This disease affects approximately 1.5 million people worldwide and can be transmitted in an autosomal dominant (ADRP) manner accounting for nearly 30% of all RP cases. Dominant rhodopsin mutations have been divided into class I and class II based on the folding of rhodopsin protein, thermal stability, and chromophore regeneration. A threonine-17-methionine (T17M) mutation in rhodopsin is a class II mutation, characterized by a thermal instability/folding defect and …

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The Effect Of Bone-Implant Contact And Elastic Modulus In The Biomechanical Stability Of Temporary Anchorage Devices, Ghada Nimeri Jan 2015

The Effect Of Bone-Implant Contact And Elastic Modulus In The Biomechanical Stability Of Temporary Anchorage Devices, Ghada Nimeri

All ETDs from UAB

ABSTRACT The purpose of this study was to analyze the microstrains of compact and trabecular bone caused by loading of different miniscrews at different healing times, and to compare these results to the limits of bone stability maintenance based on the Frost Mechanostat Theory. Materials and Methods: Theoretical calculations of microstrains of bone surrounding 10 different miniscrews were done. These miniscrews were considered under loading forces of 500 gm., and the microstains of both trabecular and compact bone were calculated separately when the thickness of the compact bone was at 1mm or 2mm. The microstrains were calculated at 4 different …

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