Medicine and Health Sciences Commons^™

Surveying Sexual And Gender Minorities, Melissa A. Clark, Samantha R. Rosenthal, Ulrike Boehmer

Health & Wellness Department Faculty Publications and Research

No abstract provided.

Androgens Alter T-Cell Immunity By Inhibiting T-Helper 1 Differentiation, Haydn T. Kissicka, Martin G. Sandab, Laura K. Dunna, Kathryn L. Pellegrinic, Seung T. Ona, Jonathan K. Noel, Mohamed S. Arredouania

Health & Wellness Department Faculty Publications and Research

No abstract provided.

The Miswak (Salvadora Persica L.) Chewing Stick: Cultural Implications In Oral Health Promotion, Basil H. Aboul-Enein

Health & Wellness Department Faculty Publications and Research

Introduction

With the increasing incidence of oral diseases attributed to poor oral hygiene, mechanical removal of dental plaque has been regarded as an effective means in the prevention of dental caries and periodontal diseases. The methods for oral hygiene vary from culture to culture and the dimensions regarding the global need for alternative prevention and effective treatment methods have expanded.

Discussion

Evidence-based studies and clinical trials have revealed the use of Salvadora persica (miswak) as an effective oral hygiene aid by which different cultures have attached functional value since ancient times.

Conclusion

The World Health Organization recommends and encourages …

A Neurobiological Model For Pathways Of Transition To Psychosis Due To Cannabis, Amresh Srivastava

Data and Test Instruments

Cannabis has been implicated as a risk factor for the development of schizophrenia, although the exact biological mechanisms remain unclear. Purpose of this presentation is to explore trajectory for psychosis due to cannabis based upon a neurobiological model. A selective Pubmed search was carried out to construct a model of pathway based upon our hypothesis. The hypothesis for this conceptual paradigm is that neurobiological changes exist and cannabis metabolites modulate these changes in a sequential manner from genetic expression, environmental and biological interaction and neurochemical dysfunctions leading to cognitive dysmatria. Dopamine remains a final common pathway which leads to core …

Five-Course Meal Infused With Information Skills And Resources, Kimberly J. Whalen, Suzanne E. Zentz

Library Faculty Publications

No abstract provided.

The New Pharmacist: 46 Doses Of Advice, Erin Albert

Butler University Books

Getting into pharmacy school: check.

Passing organic chemistry: check.

Graduating from pharmacy school: check.

Passing pharmacist board exams: check.

Landing first pharmacist job: check.

WHAT’S NEXT? Pharmacy school was the easy part. This book addresses the much more difficult part for newly licensed pharmacists: what comes after pharmacy school? This practical, yet inspirational book is for pharmacists 0-10 years into their careers, who also might ponder what else is out there—in terms of professional and career development—for years and decades to come.

Weighing The Risks And Benefits Of Radiation Exposure And Diagnostic X-Rays In Children, Leah Costello

Physician Assistant Scholarly Project Posters

The number of X-rays, specifically CT scans, performed on patients in the United States is increasing exponentially every year. Children are at most risk for long term damage from this increase in radiation exposure. This study explores how much risk children are being exposed to and how we can, as practitioners, make informed decisions about when or when not to order CT scans. The purpose of this paper is to provide practitioners the information needed to help patients decide if the long-term risks of cancer from medical radiation outweigh the potential benefit of diagnostic or therapeutic radiation. The review of …

Palivizumab Administration Decreases Recurrent Wheeze, Shelly Daniels

Physician Assistant Scholarly Project Posters

Children who have been infected with Respiratory Syncytial Virus have a higher incidence of wheeze-associated clinic visits and hospitalizations compared to children without previous RSV exposure. The purpose of this study is to determine if palivizumab, an immunoglobulin injection used to prevent RSV infections, can decrease the incidence of recurrent wheezing in children. The review of literature will follow male and female children from infancy to age 13 who were treated with palivizumab and compare these children to patients with similar demographics that were not treated with palivizumab to determine if there is any difference in incidence of wheezing. The …

Celiac Disease: Advances In Diagnostic Testing?, Alicia A. Hanson

Physician Assistant Scholarly Project Posters

• Celiac disease (CD) is a gluten-sensitivity enteropathy that occurs in genetically susceptible individuals upon ingestion of gluten and resolves when gluten is withdrawn from one’s diet.

• Serological markers play a major role in the diagnosis of celiac disease, however a small intestinal biopsy is currently the gold standard in symptomatic individuals.

• The purpose of this study was to determine if serological testing alone is sufficient to confirm the diagnosis of CD and therefore eliminate the need for a biopsy.

• The review of literature explored studies that compared small intestinal biopsy with different serological testing in males …

Happy 20th Anniversary Loma Linda University Children's Hospital, Loma Linda University Health

Scope

Table of Contents

Outreach

2 | New initiative makes health careers more accessible
4 | Covered California grant enables LLUH to educate community about new law
5 | Delighting in service: tradition of student mission trips through the years
6 | Women’s Conference: Be You – Fit | Smart | Healthy
7 | Live well, age well: making it possible for local seniors

Education

8 | Community service and formal learning come together
9 | Taking the lead on the future of public health
10 | Academic updates: the latest advances in education at LLU

Clinical

11 | NICU celebrates …

Evidence-Based Review Of Interventions For Medically At-Risk Older Drivers, Sherilenne Classen, Miriam Monahan, Beth Auten, Abraham Yarney

Collected Faculty Scholarship

OBJECTIVE. To conduct an evidence-based review of intervention studies of older drivers with medical conditions.

METHOD. We used the American Occupational Therapy Association’s classification criteria (Levels I–V, I 5 highest level of evidence) to identify driving interventions. We classified studies using letters to represent the strength of recommendations: A 5 strongly recommend the intervention; B 5 recommend intervention is provided routinely; C 5 weak evidence that the intervention can improve outcomes; D 5 recommend not to provide the intervention; I 5 insufficient evidence to recommend for or against the intervention.

RESULTS. For clients with stroke, we recommend a graded simulator …

Comment On “The Effect Of Same-Sex Marriage Laws On Different-Sex Marriage: Evidence From The Netherlands”, Alexis Dinno

Community Health Faculty Publications and Presentations

In the recent Demography article titled “The Effect of Same-Sex Marriage Laws on Different-Sex Marriage: Evidence From the Netherlands,” Trandafir attempted to answer the question, Are rates of opposite sex marriage affected by legal recognition of same sex marriages? The results of his approach to statistical inference—looking for evidence of a difference in rates of opposite-sex marriage—provide an absence of evidence of such effects. However, the validity of his conclusion of no causal relationship between same-sex marriage laws and rates of opposite-sex marriage is threatened by the fact that Trandafir did not also look for equivalence in rates of opposite-sex …

Reflections (2014 Issue), College Of Health Professions

College of Health Professions Newsletters & Magazines

"Faculty and students had another successful year of teaching and learning, scholarship and service, and they were recognized by several honors. I’m also particularly pleased with our continued to commitment to internationalize the college through expanded service learning and course offerings"--From Dean Patricia Walker's introductory message to the 2014 Reflections.

Baseline Natural Killer And T Cell Populations Correlation With Virologic Outcome After Regimen Simplification To Atazanavir/Ritonavir Alone (Actg 5201)., John E Mckinnon, Robbie B Mailliard, Susan Swindells, Timothy J Wilkin, Luann Borowski, Jillian M Roper, + 5 More

Medicine Faculty Publications

OBJECTIVES: Simplified maintenance therapy with ritonavir-boosted atazanavir (ATV/r) provides an alternative treatment option for HIV-1 infection that spares nucleoside analogs (NRTI) for future use and decreased toxicity. We hypothesized that the level of immune activation (IA) and recovery of lymphocyte populations could influence virologic outcomes after regimen simplification.

METHODS: Thirty-four participants with virologic suppression ≥ 48 weeks on antiretroviral therapy (2 NRTI plus protease inhibitor) were switched to ATV/r alone in the context of the ACTG 5201 clinical trial. Flow cytometric analyses were performed on PBMC isolated from 25 patients with available samples, of which 24 had lymphocyte recovery sufficient …

Advanced Prostate Cancer - Patient Survival And Potential Impact Of Enzalutamide And Other Emerging Therapies, Nihar K. Patel, Antoine Finianos, Kirsten D. Whitaker, Jeanny B. Aragon-Ching

Medicine Faculty Publications

The advent of exponential growth of novel agents tested and approved for the treatment of patients with metastatic castration-resistant prostate cancer (mCRPC) has brought about a need for understanding of the mechanism of action, side-effects, and clinical efficacy of these drugs as they relate to these patients. This review will provide a synopsis of the treatment landscape in mCRPC as varying agents such as abiraterone acetate, cabazitaxel, sipuleucel-T, radium, and selected emerging agents are presented. A distinct focus on the utilization of enzalutamide, its mechanism of action, key pivotal trials that brought about its US Food and Drug Administration approval, …

Need For A Standardized Protocol For Stress Echocardiography In Provoking Subaortic And Valvular Gradient In Various Cardiac Conditions, Pawel Petkow Dimitrow, Carlos Cotrim, Tsung O. Cheng

Medicine Faculty Publications

(Semi) supine exercise testing has an established role in the evaluation of patients with valvular heart disease and can help clinical decision making. Stress echocardiography has the advantages of its wide availability, low cost, and versatility for the assessment of disease severity. However, exercise-induced changes in valve hemodynamics, left ventricular outflow obstruction and pulmonary artery pressure depended on load variation. Changing position from supine to upright rapidly decreases load conditions for the ventricles. Therefore several cardiac centers have proposed exercise stress echocardiography in the upright position with gradient monitoring sometimes also in post-exercise recovery. Doppler measurement of subaortic gradient has …

Does Computerized Physician Order Entry Reduce Medical Errors?, Krista Charles, William K. Willis, Alberto Coustasse

Management Faculty Research

Introduction: Computerized Physician Order Entry (CPOE) is a system that allows physicians to electronically order patient services. The services that can be ordered, but are not limited to include: prescriptions, labs, x-rays, and referrals. Adopting CPOE will eliminate the use of paper orders with illegible hand writing. The purpose of this research project was to examine the cause of medical errors and to determine if adopting a CPOE system would be an effective solution to this problem.

Results: The results of this study show that CPOE can reduce medical errors and adverse drug events significantly. CPOE coupled with other systems …

Adolescence And Human Sexuality, Donald E. Greydanus, Hatim A. Omar

Pediatrics Faculty Publications

Human sexuality is a complex phenomenon involving the interaction of biology, sex, core gender identity, and gender role behavior. Successful completion of normal stages of sexuality development is important for children and adolescents to allow for optimal life as an adult. Controversies arise for clinicians as they work with their pediatric patients regarding health care sexuality issues. It is important that clinicians help these patients in an unbiased and neutral manner. As adults, these children and adolescents will function in a number of sexuality roles, whether heterosexual, homosexual, or bisexual. This chapter reviews many of these complex and critical issues …

Ua1c11/57 Sigma Theta Tau Photos, Wku Nursing

WKU Administration Documents

Unidentified Sigma Theta Tau photos.

End Of Life-Decisions: An Islamic Perspective, Nasser Ibrahim Abu-El-Noor Dr., Mysoon Khalil Abu-El-Noor Dr

Journal of Health Ethics

Patients who live with a low quality of life and suffer from chronic pain may wish to end their suffering through different means such as active euthanasia, passive euthanasia, and physician-assisted suicide. These alternatives to end one’s own life create many ethical dilemmas for health care professionals, patients, and family members. Some of these decisions are forbidden in Islamic Religion, while others are permitted. In this paper, the authors will discuss how Islam looks at these decisions. Knowing about how Islam deals with such decisions will be of great help for health care providers who take care of Muslim patients. …

Nursing's Ethical Responsibilities In Value-Based Purchasing, Wendy B. Bailes, Marcia M. Rachel, Sheila Keller

Journal of Health Ethics

Healthcare changes have resulted in the development of reimbursement initiatives such as value-based purchasing. These initiatives are designed to improve quality of care, decrease healthcare costs and improve the perception of care. Many of the compliance mandates are related to care provided by the professional nurse. Ethical considerations of these mandates will be explored utilizing the American Nurses Association Code of Ethics.

Prevalence Of Intestinal Parasitic Infections Among Children Under Five Years Of Age With Emphasis On Schistosoma Mansoni In Wonji Shoa Sugar Estate, Ethiopia, Yirgalem G/Hiwot, Abraham Degarege, Berhanu Erko

Journal Articles: Epidemiology

Intestinal parasite infections are major public health problems of children in developing countries causing undernutrition, anemia, intestinal obstruction and mental and physical growth retardation. This study was conducted to assess the prevalence of intestinal helminthic infections among children under five years of age with emphasis on Schistosoma mansoni in Wonji Shoa Sugar Estate, Ethiopia. A cross-sectional parasitological survey was conducted in under-five children living in Wonji Shoa Sugar Estate Ethiopia, April, 2013. Stool samples were collected and examined for intestinal parasites using single Kato-Katz and single Sodium acetate-acetic acid-formalin (SAF) solution concentration methods. Out of 374 children examined using single …

Baseline Survey Of Nigerian Media Coverage Of Youth Sexual And Reproductive Health And Hiv And Aids Related Issues, January 1st–December 31st, 2012, Population Council

HIV and AIDS

To promote more informed public dialogue on youth vulnerabilities, responses to HIV/AIDS, and positive changes in relevant policies and programs via learning and advocacy interventions at the state and national levels in Nigeria, the Population Council commissioned a study of the print and electronic media’s coverage of HIV/AIDS and sexual and reproductive health–related issues among youth aged 15–24 years in Nigeria for the period January 1 to December 31, 2012. The study entailed a content analysis of four national and two regional newspapers, and an online forum that is one of the most frequently visited social media sites in Nigeria. …

Non-Emphysematous Chronic Obstructive Pulmonary Disease Is Associated With Diabetes Mellitus, Craig P. Hersh, Barry J. Make, David A. Lynch, R. Graham Barr, Russell P. Bowler, Peter M.A. Calverley, Peter J. Castaldi, Michael H. Cho, Harvey O. Coxson, Dawn L. Demeo, Marilyn G. Foreman, Meilan K. Han, Benjamin J. Harshfield, John E. Hokanson, Sharon Lutz, Joe W. Ramsdell, Elizabeth A. Regan, Stephen I. Rennard, Joyce D. Schroeder, Frank C. Sciurba, Robert M. Steiner, Ruth Tal-Singer, Edwin Van Beek, Edwin K. Silverman, James D. Crapo, Copdgene And Eclipse Investigators

Journal Articles: Pulmonary & Critical Care Med

BACKGROUND: Chronic obstructive pulmonary disease (COPD) has been classically divided into blue bloaters and pink puffers. The utility of these clinical subtypes is unclear. However, the broader distinction between airway-predominant and emphysema-predominant COPD may be clinically relevant. The objective was to define clinical features of emphysema-predominant and non-emphysematous COPD patients.

METHODS: Current and former smokers from the Genetic Epidemiology of COPD Study (COPDGene) had chest computed tomography (CT) scans with quantitative image analysis. Emphysema-predominant COPD was defined by low attenuation area at -950 Hounsfield Units (LAA-950) ≥10%. Non-emphysematous COPD was defined by airflow obstruction with minimal to no emphysema (LAA-950 …

Sexually-Dimorphic Targeting Of Functionally-Related Genes In Copd, Kimberly Glass, John Quackenbush, Edwin K. Silverman, Bartolome Celli, Stephen I. Rennard, Guo-Cheng Yuan, Dawn L. Demeo

Journal Articles: Pulmonary & Critical Care Med

BACKGROUND: There is growing evidence that many diseases develop, progress, and respond to therapy differently in men and women. This variability may manifest as a result of sex-specific structures in gene regulatory networks that influence how those networks operate. However, there are few methods to identify and characterize differences in network structure, slowing progress in understanding mechanisms driving sexual dimorphism.

RESULTS: Here we apply an integrative network inference method, PANDA (Passing Attributes between Networks for Data Assimilation), to model sex-specific networks in blood and sputum samples from subjects with Chronic Obstructive Pulmonary Disease (COPD). We used a jack-knifing approach to …

Herbal And Holistic Medicine In Mexico And Peru, William H. Lyle

Student Research Conference Select Presentations

No abstract provided.

Child Weight And Feeding Patterns In An Old Order Mennonite Community, Dawn M. Garrett Wright, Maria E. Main, M. Susan Jones

Nursing Faculty Publications

Feeding practices in some religious communities may decrease childhood obesity. However, there is limited research in these communities to assess maternal perceptions of their children’s weight and feeding patterns. The purpose of this study was to ascertain Old Order Mennonite mothers’ perceptions of their children’s body weight and to examine feeding patterns for their children. Sample: Participants for this descriptive, correlational study were recruited from an Old Order Mennonite community in south central Kentucky. Sampling was achieved using a snowball sampling strategy and the use of a community insider. Methods: Body Mass Index was measured for mothers and child participants, …

Can Follow Up Phone Calls Decrease Complications Of Chemotherapy Toxicities In Adults?, Maire M. Blankenship

Doctor of Nursing Practice Technical Reports

Approximately 22% of all cancer patients in the United States receive chemotherapy. Older adults account for 60 % of new cancer diagnoses in the United States. The aging process is associated with comorbidities that potentially can increase toxicities associated with chemotherapy. These include coronary artery disease, hypertension, and diabetes. Monitoring for toxicities during treatment and intervening when needed allows patients to move forward in their treatment plan. Interruptions in the treatment plan have the potential to adversely affect treatment goals. The purpose of this study is to determine if patients receiving phone calls on predetermined days had fewer days of …

2014 Abstracts Student Research Conference, Student Research Conference

Student Research Conference Select Presentations

No abstract provided.

Day-To-Day Fluctuation Of Point-Of-Care Circulating Cathodic Antigen Test Scores And Faecal Egg Counts In Children Infected With Schistosoma Mansoni In Ethiopia, Abraham Degarege, Mengistu Legesse, Girmay Medhin, Tilahun Teklehaymanot, Berhanu Erko

Journal Articles: Epidemiology

BACKGROUND: Determining the variation of circulating cathodic antigen (CCA) in urine and egg counts variation in stool between days in Schistosoma mansoni (S. mansoni) infected individuals is vital to decide whether or not to rely on a single-sample test for diagnosis of Schistosomiasis. In this study, the magnitude of day-to-day variation in urine-CCA test scores and in faecal egg counts was evaluated in school children in Ethiopia.

METHODS: A total of 620 school children (age 8 to 12 years) were examined for S. mansoni infection using double Kato-Katz and single urine-CCA cassette methods (batch 32727) on three consecutive days.

RESULTS: …