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Articles 1051 - 1080 of 11524
Full-Text Articles in Medicine and Health Sciences
Association Between Depression On Diet And Glycemic Control In Type 2 Diabetic Patients, J Wirunrat, S. Pongthananikorn
Association Between Depression On Diet And Glycemic Control In Type 2 Diabetic Patients, J Wirunrat, S. Pongthananikorn
Chulalongkorn Medical Journal
Background : Diabetes mellitus is a chronic disease with high and rising prevalence worldwide. Diabetic patients have to control their levels of blood sugar to avoid complications. Diet control is one of the important factors that condition blood sugar level. Several studies showed that the prevalence of depression was high in chronic patients including diabetes, and depression affects the self-care behaviors. Objective : To examine for the association between depression and diet control cooperation as well as glycemic control in patients with type 2 diabetes. Design : This research is a cross-sectional study. Setting : Diabetes Clinic, Outpatient Department, Phuthasothon …
Arborists Die After Falling, Kentucky Injury Prevention And Research Center
Arborists Die After Falling, Kentucky Injury Prevention And Research Center
Kentucky Haz Alerts--Falls
To Prevent Arborists Injuries:
- Never allow an aerial lift to be used as a crane or material lifting device.
- All trees and limbs should be inspected for structural weakness such as rot, before work starts.
- Arborists should wear appropriate personal protective equipment while performing tree trimming activities.
Special Factors for Aerial Lifts:
- Do not exceed the boom and basket load limits specified by the manufacturer.
- When working from an aerial lift, use a body harness that is properly attached.
Cyclin E Induction And Oncolytic Replication Of E1b-Deleted Adenoviruses., Pei-Hsin Cheng
Cyclin E Induction And Oncolytic Replication Of E1b-Deleted Adenoviruses., Pei-Hsin Cheng
Electronic Theses and Dissertations
Virus-mediated oncolysis has been considered as a new and promising cancer therapeutic approach. Although adenoviruses (Ads) with deletion of E1b55K preferentially replicate in cancer cells and have been used in numerous cancer treatments, the selective replication mechanism of this kind of virus still remains controversial. The lack of a well-established studies focusing on possible mechanisms enabling tumor selectivity of oncolytic Ads has hindered the further development of virotherapies and limits their clinical applications. Therefore, uncovering the molecular basis behind the tumor-killing phenomena will fill critical gaps in our understanding of the oncolytic adenovirology. Previously our laboratory has demonstrated that Ad …
Intraosseous Vascular Access For Alert Patients, Stacie Hunsaker
Intraosseous Vascular Access For Alert Patients, Stacie Hunsaker
Faculty Publications
Nurses are often faced with the challenge of starting an IV line in a patient who is dehydrated, has suffered trauma, or is in shock. Even the efforts of the most skilled clinician may fail, while valuable time is lost. Intraosseous access is a rapid, safe, and effective route for delivering fluids and medications, and is recommended by numerous professional and specialty organizations for both pediatric and adult patients. Yet many clinicians remain unaware of the procedure. This article outlines the procedure and devices used, describes support for use in the literature, and discusses various considerations and nursing implications.
Incidence And Outcome Of Small For Gestational Age Fetuses: An Experience From A Secondary Care Hospital, Riffat Bano, Nousheen Asim, Ammara Mushtaq, Mehreen Adhi, Noureen Afzal
Incidence And Outcome Of Small For Gestational Age Fetuses: An Experience From A Secondary Care Hospital, Riffat Bano, Nousheen Asim, Ammara Mushtaq, Mehreen Adhi, Noureen Afzal
Department of Obstetrics & Gynaecology
The objective of the study was to determine the frequency and outcome of Small for Gestational Age (SGA) foetuses, and its association with the mode of delivery, foetal birthweight, maternal age and gestational age. It was a hospital-based descriptive study, conducted at Aga Khan Hospital for Women, Karachi, from January 2009 to December 2010. Mode of deliveries, foetal birthweight, maternal age and gestational age of SGA foetuses were recorded and analszed. Of a total of 6024 deliveries during the study period, 722(11.98%) had SGA foetuses. Maternal age in such cased ranged between 20-40 years in 588(81.44%), while 406(56.23%) of these …
Heart Smart: Healthy Living And Prevention Of Chronic Disease, Ginger D. Cameron
Heart Smart: Healthy Living And Prevention Of Chronic Disease, Ginger D. Cameron
Pharmacy Practice Faculty Presentations
No abstract provided.
Physiological Arousal In Autism And Fragile X Syndrome: Group Comparisons And Links With Pragmatic Language, Jessica Klusek, G E. Martin, M Losh
Physiological Arousal In Autism And Fragile X Syndrome: Group Comparisons And Links With Pragmatic Language, Jessica Klusek, G E. Martin, M Losh
Faculty Publications
No abstract provided.
Music At The End Of Life: Bringing Comfort And Saying Goodbye Through Song And Story, Amy Clements-Cortés
Music At The End Of Life: Bringing Comfort And Saying Goodbye Through Song And Story, Amy Clements-Cortés
Music Faculty Publications
Music has been an important part of the human existence across all continents and cultures since the beginning of recorded time. It is used, for example, in the celebration of happy events, for religious rituals, and to acknowledge the death of loved ones, often as part of spiritual and symbolic rituals. Although the formal and structured use of music as a component of care for individuals in end-of-life palliative care and hospice systems is relatively new in the world of contemporary medicine, its use is growing rapidly and is appreciated by both those providing the music and those receiving the …
Soothing The Threatened Brain: Leveraging Contact Comfort With Emotionally Focused Therapy, Susan M. Johnson, Melissa Burgess Moser, Lane Beckes, Andra Smith, Rebecca Halchuk, Karen Hasselmo, Paul S. Greenman, Zul Merali, James A. Coan
Soothing The Threatened Brain: Leveraging Contact Comfort With Emotionally Focused Therapy, Susan M. Johnson, Melissa Burgess Moser, Lane Beckes, Andra Smith, Rebecca Halchuk, Karen Hasselmo, Paul S. Greenman, Zul Merali, James A. Coan
Brain and Mind Institute
Social relationships are tightly linked to health and well-being. Recent work suggests that social relationships can even serve vital emotion regulation functions by minimizing threat-related neural activity. But relationship distress remains a significant public health problem in North America and elsewhere. A promising approach to helping couples both resolve relationship distress and nurture effective interpersonal functioning is Emotionally Focused Therapy for couples (EFT), a manualized, empirically supported therapy that is strongly focused on repairing adult attachment bonds. We sought to examine a neural index of social emotion regulation as a potential mediator of the effects of EFT. Specifically, we examined …
Design And Configuration Of Laser Tweezers Microscopy For Force Measurements On Single Dna Molecules, Carlos Jeziel Gonzalez Banuelos
Design And Configuration Of Laser Tweezers Microscopy For Force Measurements On Single Dna Molecules, Carlos Jeziel Gonzalez Banuelos
Theses and Dissertations - UTB/UTPA
In this study, a detailed description of the optical tweezers microscopy technique is presented, as well as the methodologies used to prepare the DNA molecule for mechanical measurements at the nanoscale. The main objective is to initiate and extend the experimental biophysical studies on the DNA-proteins interactions at the University of Texas at Brownsville (UTB). DNA-binding proteins control almost all aspects of cellular function, such as transcription; chromosome maintenance, replication and DNA repair depend on the interaction of proteins with DNA. In view of such an important role played by DNA–protein interactions, various techniques have evolved over the years to …
Jfma Street Outreach: A Resident-Run Street Medicine Program A Retrospective Chart Review Examining The Needs Of A Vulnerable Population And Services Provided, Kenneth E. Hemba, Md, Rebecca Simon, Bs, Lara Carson Weinstein, Md
Jfma Street Outreach: A Resident-Run Street Medicine Program A Retrospective Chart Review Examining The Needs Of A Vulnerable Population And Services Provided, Kenneth E. Hemba, Md, Rebecca Simon, Bs, Lara Carson Weinstein, Md
Department of Family & Community Medicine Presentations and Grand Rounds
In Philadelphia it is estimated that over 12,000 people experience homelessness annually, and up to 500 individuals live on the street on any given day.1
Project HOME coordinates the City of Philadelphia’s outreach effort aimed at forming relationships with unsheltered individuals, identifying their barriers to entering permanent supportive housing and assisting them in overcoming these barriers.
Having identified this population’s need for medical services, in 2007 faculty in Jefferson Family Medicine Associates (JFMA) reached out to Project HOME and extended an ongoing community-academic partnership.
Since then Family Medicine residents and students have been traveling with the outreach team, meeting …
A Rare Aetiology Of Respiratory Failure In A 10-Year-Old Boy: Inflammatory Myofibroblastic Tumour., Ali Khawaja, Prem Kumar Maheshwar, Anwarul Haque, Ali Bin Sarwar Zubairi
A Rare Aetiology Of Respiratory Failure In A 10-Year-Old Boy: Inflammatory Myofibroblastic Tumour., Ali Khawaja, Prem Kumar Maheshwar, Anwarul Haque, Ali Bin Sarwar Zubairi
Department of Medicine
Primary neoplasms of the respiratory tract are rarely encountered in the paediatric population. Inflammatory myofibroblastic tumour (IMT) is a rare soft tissue mesenchymal tumour but a distinct disease entity accounting for less than 1% of all primary lung tumours. We report a case of a 10-year-old boy who presented with respiratory failure and left lung collapse. On flexible fiberoptic bronchoscopy, a pedunculated mass in the lower part of the trachea originating from the left main stem bronchus was identified. The patient subsequently underwent a left-sided pneumonectomy with complete resection of the mass. The histopathological analysis was consistent with IMT. Two …
Melorheostosis And Central Giant Cell Granuloma Of The Mandible In A 15-Year-Old Girl, Kenneth M. Anderson, W. H. Shintaku, Molly S. Rosebush, Yeshwant B. Rawal, E. S. Woodard
Melorheostosis And Central Giant Cell Granuloma Of The Mandible In A 15-Year-Old Girl, Kenneth M. Anderson, W. H. Shintaku, Molly S. Rosebush, Yeshwant B. Rawal, E. S. Woodard
School of Dentistry Faculty Research and Publications
Melorheostosis is a nonhereditary bone dysplasia primarily affecting the appendicular skeleton. Because clinical and histologic features are often nonspecific, the diagnosis is often based on the radiographic presentation. Involvement of the craniofacial skeleton is rare. We describe a case of a 15-year-old girl with appendicular and craniofacial melorheostosis with adjacent central giant cell granuloma. We discuss the possible significance of this previously unreported finding.
The Predictive Validity Of Selection For Entry Into Postgraduate Training In General Practice: Evidence From Three Longitudinal Studies, Fiona Patterson, Filip Lievens, Maire Kerrin, Neil Munro, Bill Irish
The Predictive Validity Of Selection For Entry Into Postgraduate Training In General Practice: Evidence From Three Longitudinal Studies, Fiona Patterson, Filip Lievens, Maire Kerrin, Neil Munro, Bill Irish
Research Collection Lee Kong Chian School Of Business
Background: The selection methodology for UK general practice is designed to accommodate several thousand applicants per year and targets six core attributes identified in a multi-method job-analysis study. Aim: To evaluate the predictive validity of selection methods for entry into postgraduate training, comprising a clinical problem-solving test, a situational judgement test, and a selection centre. Design and setting: A three-part longitudinal predictive validity study of selection into training for UK general practice. Method: In sample 1, participants were junior doctors applying for training in general practice (n = 6824). In sample 2, participants were GP registrars 1 year into training …
Public Health Considerations Of Launching Nuclear Waste To The Sun, Murray R. Berkowitz
Public Health Considerations Of Launching Nuclear Waste To The Sun, Murray R. Berkowitz
PCOM Scholarly Papers
The article discusses the public health aspects of disposing of radioactive nuclear waste by launching it to the sun. Disposing of radioactive nuclear waste by launching it to the sun remove the threats of exposure from leakage of a storage facility. The high temperatures will incinerate and consume all matter prior to its reaching the sun's corona.
Underrepresented Minorities In Medical School Admissions: Developing A Theoretical Model, Margaret A. Hadinger Edd, Ms
Underrepresented Minorities In Medical School Admissions: Developing A Theoretical Model, Margaret A. Hadinger Edd, Ms
Department of Education
No abstract provided.
Select Readiness: Results Of A Comprehensive Assessment Of The Clinical Learning Environment Of A Branch Medical Campus, Margaret A. Hadinger Edd, Ms, Hubert K. Huang Ms, Med, Erica T. Mahady Ma, Jody Millard Ma, Edward R. Norris Md, Fapa, Fapm, J Alan Otsuki Md, Mba
Select Readiness: Results Of A Comprehensive Assessment Of The Clinical Learning Environment Of A Branch Medical Campus, Margaret A. Hadinger Edd, Ms, Hubert K. Huang Ms, Med, Erica T. Mahady Ma, Jody Millard Ma, Edward R. Norris Md, Fapa, Fapm, J Alan Otsuki Md, Mba
Department of Education
No abstract provided.
1,000 Miles Next Door: The Development Of A Branch Medical Campus, Margaret A. Hadinger Edd, Ms, Jennifer D. Mccormick Mba, J Alan Otsuki Md, Mba
1,000 Miles Next Door: The Development Of A Branch Medical Campus, Margaret A. Hadinger Edd, Ms, Jennifer D. Mccormick Mba, J Alan Otsuki Md, Mba
Department of Education
No abstract provided.
Predictors Of Dental Care Use: Findings From The National Longitudinal Study Of Adolescent Health, Christopher Okunseri, Elaye Okunseri, Raul I. Garcia, Alexis D. Visotcky, Aniko Szabo
Predictors Of Dental Care Use: Findings From The National Longitudinal Study Of Adolescent Health, Christopher Okunseri, Elaye Okunseri, Raul I. Garcia, Alexis D. Visotcky, Aniko Szabo
School of Dentistry Faculty Research and Publications
Purpose
To examine longitudinal trends and associated factors in dental service utilization by adolescents progressing to early adulthood in the United States.
Methods
The data source was the National Longitudinal Study of Adolescent Health from Waves I (1994–1995), II (1996), III (2001–2002), and IV (2007–2008). This was a retrospective, observational study of adolescents' transition to early adulthood. We obtained descriptive statistics and performed logistic regression analyses to identify the effects of baseline and concurrent covariates on dental service utilization from adolescence to early adulthood over time.
Results
Dental service utilization within the prior 12 months peaked at age 16 (72%), …
Embracing A Competency-Based Specialty Curriculum For Community-Based Nursing Roles, Pamela F. Levin, Susan M. Swider, Susan Breakwell, Julia M. Cowell, Virginia Reising
Embracing A Competency-Based Specialty Curriculum For Community-Based Nursing Roles, Pamela F. Levin, Susan M. Swider, Susan Breakwell, Julia M. Cowell, Virginia Reising
College of Nursing Faculty Research and Publications
The Quad Council competencies for public health nursing (PHN) provide guidance in developing curricula at both the generalist and specialist level. However, these competencies are based on nursing roles in traditional public health agencies and community/public health is defined more broadly than official agency practice. The question arises as to whether community-based specialties require largely the same knowledge and skill set as PHN. The purpose of the competency cross-mapping project reported here was to (a) assess the intersection of the Quad Council competencies with four community-based specialties and (b) ensure the appropriateness of a Quad Council-based curriculum to prepare graduates …
Harnessing Poverty Alleviation To Reduce The Stigma Of Hiv In Sub-Saharan Africa, Alexander C. Tsai, David Bangsberg, Sheri D. Weiser
Harnessing Poverty Alleviation To Reduce The Stigma Of Hiv In Sub-Saharan Africa, Alexander C. Tsai, David Bangsberg, Sheri D. Weiser
OHSU-PSU School of Public Health Faculty Publications and Presentations
HIV is highly stigmatized throughout sub-Saharan Africa. In studies conducted among general population samples, stigma has been shown to impede uptake of HIV testing and increase sexual risktaking behavior. Among HIV-infected persons, stigma has also been associated with inhibited serostatus disclosure to sexual partners and potential treatment supporters, delays in HIV antiretroviral therapy (ART) initiation, and ART nonadherence. The stigma of HIV also intensifies the poverty, stress, and insecurity endemic to many resource-limited settings, resulting in worsened mental health, itself an important determinant of AIDS-related mortality. Until we can better understand how to effectively intervene to reduce the stigma of …
Factors Associated With Pruritic Papular Eruption Of Human Immunodeficiency Virus Infection In The Antiretroviral Therapy Era, S. L. Chua, E. H. Amerson, K. S. Leslie, T. H. Mccalmont, P. E. Leboit, J. N. Martin, David Bangsberg, T. A. Maurer
Factors Associated With Pruritic Papular Eruption Of Human Immunodeficiency Virus Infection In The Antiretroviral Therapy Era, S. L. Chua, E. H. Amerson, K. S. Leslie, T. H. Mccalmont, P. E. Leboit, J. N. Martin, David Bangsberg, T. A. Maurer
OHSU-PSU School of Public Health Faculty Publications and Presentations
Background—Pruritic papular eruption (PPE) of HIV is common in HIV-infected populations living in the tropics. Its aetiology has been attributed to insect bite reactions and it is reported to improve with antiretroviral therapy (ART). Its presence after at least 6 months of ART has been proposed as one of several markers of treatment failure.
Objectives—To determine factors associated with PPE in HIV-infected persons receiving ART.
Methods—A case–control study nested within a 500-person cohort from a teaching hospital in Mbarara, Uganda. Forty-five cases and 90 controls were enrolled. Cases had received ART for ≥ 15 months and had an itchy papular …
Predictors Of Disease Progression In Pediatric Dilated Cardiomyopathy., Kimberly M. Molina, Peter Shrader, Steven D. Colan, Seema Mital, Renee Margossian, Lynn A. Sleeper, Girish S. Shirali, Piers Barker, Charles E. Canter, Karen Altmann, Elizabeth Radojewski, Elif Seda Selamet Tierney, Jack Rychik, Lloyd Y. Tani, Pediatric Heart Network Investigators
Predictors Of Disease Progression In Pediatric Dilated Cardiomyopathy., Kimberly M. Molina, Peter Shrader, Steven D. Colan, Seema Mital, Renee Margossian, Lynn A. Sleeper, Girish S. Shirali, Piers Barker, Charles E. Canter, Karen Altmann, Elizabeth Radojewski, Elif Seda Selamet Tierney, Jack Rychik, Lloyd Y. Tani, Pediatric Heart Network Investigators
Manuscripts, Articles, Book Chapters and Other Papers
Background: Despite medical advances, children with dilated cardiomyopathy (DCM) remain at high risk of death or need for cardiac transplantation. We sought to identify predictors of disease progression in pediatric DCM.
Methods and results: The Pediatric Heart Network evaluated chronic DCM patients with prospective echocardiographic and clinical data collection during an 18-month follow-up. Inclusion criteria were age <22 years and DCM disease duration >2 months. Patients requiring intravenous inotropic/mechanical support or listed status 1A/1B for transplant were excluded. Disease progression was defined as an increase in transplant listing status, hospitalization for heart failure, intravenous inotropes, mechanical support, or death. Predictors of disease progression were identified using …22>
Multicenter Study Comparing Shunt Type In The Norwood Procedure For Single-Ventricle Lesions: Three-Dimensional Echocardiographic Analysis., Gerald R. Marx, Girish S. Shirali, Jami C. Levine, Lin T. Guey, James F. Cnota, Jeanne M. Baffa, William L. Border, Steve Colan, Gregory Ensing, Mark K. Friedberg, David J. Goldberg, Salim F. Idriss, J Blaine John, Wyman W. Lai, Minmin Lu, Shaji C. Menon, Richard G. Ohye, David Saudek, Pierre C. Wong, Gail D. Pearson, Pediatric Heart Network Investigators
Multicenter Study Comparing Shunt Type In The Norwood Procedure For Single-Ventricle Lesions: Three-Dimensional Echocardiographic Analysis., Gerald R. Marx, Girish S. Shirali, Jami C. Levine, Lin T. Guey, James F. Cnota, Jeanne M. Baffa, William L. Border, Steve Colan, Gregory Ensing, Mark K. Friedberg, David J. Goldberg, Salim F. Idriss, J Blaine John, Wyman W. Lai, Minmin Lu, Shaji C. Menon, Richard G. Ohye, David Saudek, Pierre C. Wong, Gail D. Pearson, Pediatric Heart Network Investigators
Manuscripts, Articles, Book Chapters and Other Papers
BACKGROUND: The Pediatric Heart Network's Single Ventricle Reconstruction (SVR) trial randomized infants with single right ventricles (RVs) undergoing a Norwood procedure to a modified Blalock-Taussig or RV-to-pulmonary artery shunt. This report compares RV parameters in the 2 groups using 3-dimensional echocardiography.
METHODS AND RESULTS: Three-dimensional echocardiography studies were obtained at 10 of 15 SVR centers. Of the 549 subjects, 314 underwent 3-dimensional echocardiography studies at 1 to 4 time points (pre-Norwood, post-Norwood, pre-stage II, and 14 months) for a total of 757 3-dimensional echocardiography studies. Of these, 565 (75%) were acceptable for analysis. RV volume, mass, mass:volume ratio, ejection fraction, …
Optimal Control In The Treatment Of Retinitis Pigmentosa, Erika T. Camacho, Luis A. Melara, Cristina Villalobos, Stephen Wirkus
Optimal Control In The Treatment Of Retinitis Pigmentosa, Erika T. Camacho, Luis A. Melara, Cristina Villalobos, Stephen Wirkus
School of Mathematical and Statistical Sciences Faculty Publications and Presentations
Numerous therapies have been implemented in an effort to minimize the debilitating effects of the degenerative eye disease Retinitis Pigmentosa (RP), yet none have provided satisfactory long-term solution. To date there is no treatment that can halt the degeneration of photoreceptors. The recent discovery of the RdCVF protein has provided researchers with a potential therapy that could slow the secondary wave of cone death. In this work, we build on an existing mathematical model of photoreceptor interactions in the presence of RP and incorporate various treatment regiments via RdCVF. Our results show that an optimal control exists for the administration …
Job's Syndrome With An Atypical Presentation, Abbas Ali Tasneem, Sabahat Sarfaraz, Syed Mujahid Hassan, Nasir Hassan Luck, Sabiha Anis, Zaigham Abbas
Job's Syndrome With An Atypical Presentation, Abbas Ali Tasneem, Sabahat Sarfaraz, Syed Mujahid Hassan, Nasir Hassan Luck, Sabiha Anis, Zaigham Abbas
Section of Gastroenterology
Hyper Immunoglobulin E syndrome also called Job's or Buckley Syndrome is a rare primary immunodeficiency disease characterized by elevated serum IgE levels (> 2000 IU/ml), recurrent infections and eosinophilia. Other features include coarse facies and non-immunologic abnormalities of the dentition, bones, vasculature and connective tissues. We are reporting a case of a twenty four years old male with coarse facies who presented with severe pallor and upper gastrointestinal bleeding. Investigations revealed markedly elevated serum IgE levels (11,800 IU/ml), severe anaemia, esophageoduodenal erosions, Helicobacter pylori (H. pylori) gastritis and oro-esophageal candidiasis.
The Concomitant Relationship Shared By Sleep Disturbances And Type 2 Diabetes: Developing Telemedicine As A Viable Treatment Option, Pennie S. Seibert, Jennifer Valerio, Codieann Dehaas
The Concomitant Relationship Shared By Sleep Disturbances And Type 2 Diabetes: Developing Telemedicine As A Viable Treatment Option, Pennie S. Seibert, Jennifer Valerio, Codieann Dehaas
Psychological Sciences Faculty Publications and Presentations
Individually, sleep disturbances and type 2 diabetes pose pervasive challenges to health. In addition, the negative symptomology associated with each condition is exacerbated further when presenting concomitantly. This relationship formulates a destructive loop wherein those with diabetes experience decreased sleep quality, which, in turn, worsens a wide range of health threats experienced by those with diabetes, including obesity and glucose intolerance. Because major lifestyle changes and daily care are needed to effectively manage both diabetes and sleep disturbances, an efficient and timely modality of treatment is essential. Advanced technology incorporating telemedicine and telehealth has the potential to enhance treatment by …
The Biology And Taxonomy Of Head And Body Lice: Implications For Louse-Borne Disease Prevention, Denise L. Bonilla, Lance A. Durden, Marina E. Eremeeva, Gregory A. Dasch
The Biology And Taxonomy Of Head And Body Lice: Implications For Louse-Borne Disease Prevention, Denise L. Bonilla, Lance A. Durden, Marina E. Eremeeva, Gregory A. Dasch
Harold W. Manter Laboratory: Library Materials
Sucking lice (Phthiraptera: Anoplura) are obligate blood-feeding ectoparasites of placental mammals including humans. Worldwide, more than 550 species have been described and many are specific to a particular host species of mammal. Three taxa uniquely parasitize humans: the head louse, body louse, and crab (pubic) louse. The body louse, in particular, has epidemiological importance because it is a vector of the causative agents of three important human diseases: epidemic typhus, trench fever, and louse-borne relapsing fever. Since the advent of antibiotics and more effective body louse control measures in the 1940s, these diseases have markedly diminished in incidence. However, due …
Reduced White Matter Integrity In Sibling Pairs Discordant For Bipolar Disorder, Emma Sprooten, Margaret S. Brumbaugh, Emma E. Knowles, D Reese Mckay, John Lewis, Jennifer Barrett, Stefanie Landau, Lindsay Cyr, Peter Kochunov, Anderson M. Winkler
Reduced White Matter Integrity In Sibling Pairs Discordant For Bipolar Disorder, Emma Sprooten, Margaret S. Brumbaugh, Emma E. Knowles, D Reese Mckay, John Lewis, Jennifer Barrett, Stefanie Landau, Lindsay Cyr, Peter Kochunov, Anderson M. Winkler
School of Medicine Publications and Presentations
Objective
Several lines of evidence indicate that white matter integrity is compromised in bipolar disorder, but the nature, extent, and biological causes remain elusive. To determine the extent to which white matter deficits in bipolar disorder are familial, the authors investigated white matter integrity in a large sample of bipolar patients, unaffected siblings, and healthy comparison subjects.
Method
The authors collected diffusion imaging data for 64 adult bipolar patients, 60 unaffected siblings (including 54 discordant sibling pairs), and 46 demographically matched comparison subjects. Fractional anisotropy was compared between the groups using voxel-wise tract-based spatial statistics and by extracting mean fractional …
Cholera Vaccination Campaign Contributes To Improved Knowledge Regarding Cholera And Improved Practice Relevant To Waterborne Disease In Rural Haiti, Omowunmi Aibana, Molly F Franke, Jessica E Teng, Johanne Hilaire, Max Raymond, Louise C Ivers
Cholera Vaccination Campaign Contributes To Improved Knowledge Regarding Cholera And Improved Practice Relevant To Waterborne Disease In Rural Haiti, Omowunmi Aibana, Molly F Franke, Jessica E Teng, Johanne Hilaire, Max Raymond, Louise C Ivers
Journal Articles
BACKGROUND: Haiti's cholera epidemic has been devastating partly due to underlying weak infrastructure and limited clean water and sanitation. A comprehensive approach to cholera control is crucial, yet some have argued that oral cholera vaccination (OCV) might result in reduced hygiene practice among recipients. We evaluated the impact of an OCV campaign on knowledge and health practice in rural Haiti.
METHODOLOGY/PRINCIPAL FINDINGS: We administered baseline surveys on knowledge and practice relevant to cholera and waterborne disease to every 10th household during a census in rural Haiti in February 2012 (N = 811). An OCV campaign occurred from May-June 2012 after …