Medicine and Health Sciences Commons^™

Predictors Of Perioperative Blood Loss In Total Joint Arthroplasty., Jai Hyung Park, Mohammad R Rasouli, S M Javad Mortazavi, Anthony T Tokarski, Mitchell G Maltenfort, Javad Parvizi

Rothman Institute Papers

UNLABELLED: UPDATE The print version of this article has errors that have been corrected in the online version of this article. In the Materials and Methods section, the sentence that reads as "During the study period, our institution offered preoperative autologous blood donation to all patients who were scheduling for total joint arthroplasty with a hemoglobin level of no less than 11 mg/dL or a hematocrit level of at least 33%." in the print version now reads as "During the study period, our institution offered preoperative autologous blood donation to all patients who were scheduling for total joint arthroplasty with …

Defining The Vulnerable Period For Re-Establishment Of Clostridium Difficile Colonization After Treatment Of C. Difficile Infection With Oral Vancomycin Or Metronidazole, Venkata C.K. Sunkesula, Sirisha Kundrapu, Robin L. Jump, Curtis J. Donskey

Faculty Scholarship

Background:Clostridium difficile is an anaerobic, spore-forming bacterium that is the most common cause of healthcare-associated diarrhea in developed countries. A significant proportion of patients receiving oral vancomycin or metronidazole for treatment of Clostridium difficile infection (CDI) develop recurrences. However, the period of vulnerability to re-establishment of colonization by C. difficile after therapy is not well defined.Principal Findings:In a prospective study of CDI patients, we demonstrated that most vancomycin-treated patients maintained inhibitory concentrations of vancomycin in stool for 4 to 5 days after therapy, whereas metronidazole was only detectable during therapy. From the time of elimination of the antibiotics to 14 …

Recommendations For High-Priority Research On Cancer-Related Fatigue In Children And Adults., Andrea M. Barsevick, Michael R. Irwin, Pamela Hinds, Andrew Miller, Ann Berger, Paul Jacobsen, Sonia Ancoli-Israel, Bryce B Reeve, Karen Mustian, Ann O'Mara, Jin-Shei Lai, Michael Fisch, David Cella

Department of Medical Oncology Faculty Papers

Over the past decades, some scientific progress has been made in understanding and treating cancer-related fatigue (CRF). However, three major problems have limited further progress: lack of agreement about measurement, inadequate understanding of the underlying biology, and problems in the conduct of clinical trials for CRF. This commentary reports the recommendations of a National Cancer Institute Clinical Trials Planning Meeting and an ongoing National Cancer Institute working group to address these problems so that high-priority research and clinical trials can be conducted to advance the science of CRF and its treatment. Recommendations to address measurement issues included revising the current …

Bis-Pyridino Containing Compounds For The Use In The Treatment Of Cns Pathologies, Peter A. Crooks, Linda P. Dwoskin, Joshua Ayers, Vladimir Grinevich, Sangeetha Sumithran

Pharmaceutical Sciences Faculty Patents

N-n-Alkylation of nicotine converts nicotine from an agonist into an antagonist specifically for neuronal nicotinic acetylcholine receptor subtypes mediating nicotine-evoked dopamine release. Conformationally restricted analogs exhibit both high affinity and selectivity at this site, and are able to access the brain due to their ability to act as substrates for the blood-brain barrier choline transporter.

Health Sciences Library Newsletters, Maria Roman

Library Newsletters

Baystate Medical Center Health Sciences Library Newsletter

Integrative Health Studies Newsletter, Ciis

Integrative Health Studies Newsletter

This is the Fall 2013 issue of the Integrative Health Studies Newsletter at CIIS.

Integrative Health Studies Newsletter, Ciis

Integrative Health Studies Newsletter

This is the Fall 2013 issue of the Integrative Health Studies Newsletter at CIIS.

Healthnet News V.28:No.3 Fall 2013, Judith S. Kronick, Alberta Richetelle

Articles - Patient Care

A newsletter for public librarians and others interested in consumer health information services.

Department Of Surgery Update, Acs Special Edition, Wright State University Department Of Surgery

Department of Surgery Updates

A three page newsletter created by the Department of Surgery documenting changes to the department. This issue features images from an event for the American College of Surgeons (ACS) and lists the ACS Fellow for that year.

Illusion Or Ununderstood Reality: Spiritual Or Psychic Healing And Protection In Southern Madagascar, Henri Lucien Sandifer

Independent Study Project (ISP) Collection

Far from the hospital room and its doctor, the medicine and philosophies of Lakazy and its Ombiasa pertain to a domain largely untouched by western logic and science. Their practices appear to be effective and unique enough to have survived the advent of compelling new theological and scientific belief systems and the vastly different perspectives on community health and stability which these systems have brought to Madagascar. The prime examples of these new arrivals are Christianity and modern medicine, respectively. Within and without their sacred space, the mission of the true Ombiasa is to support their community and for this …

The Mosakowski Institute For Public Enterprise Five Year Report, Mosakowski Institute

Mosakowski Institute for Public Enterprise

This report contains the highlights of the first five years of Clark University’s Mosakowski Institute for Public Enterprise. It includes a description of the Institute’s founding, its commitment to use-inspired research, transformational educational experiences, and community connectedness, the Institute’s leadership and finances, and a listing of projects undertaken and faculty partners.

Mid-Atlantic Ethics Committee Newsletter, Fall 2013

Mid-Atlantic Ethics Committee Newsletter

No abstract provided.

Com Outlook Fall 2013, College Of Osteopathic Medicine

COM Outlook

No abstract provided.

2012-2013 Hccp Year-End Summary, Kristen S. Cloutier

Year-end Summaries

No abstract provided.

Dental Student Debt In The U.S.: A Mountain To Be Scaled, David G. Dunning

Journal Articles: College of Dentistry

Dental student educational debt in the United States continues to grow as a concern for both dental educators and dental students. While certainly warranted, this concern needs to be understood from the perspective of return on investment. The student debt issue remains a critical one. However, this debt is essentially “good” debt when viewed as an investment made by associates/ employees of general dental practices and general dental practice owners.

Analytical Methods For Planning And Scheduling Daily Work In Inpatient Care Settings: Opportunities For Research And Practice, Laila Cure Ph.D.

Transactions of the International Conference on Health Information Technology Advancement

This article identifies current challenges in the planning and execution of daily work in inpatient care settings. Inadequate planning of the processes and resources associated with inpatient care services may negatively affect their effectiveness. It may also lead to burnout of healthcare workers when the resulting work plan is unknowingly infeasible or does not incorporate the necessary human factors considerations. This paper provides with an overview of current research on inpatient care workflow planning, as well as with directions for researchers and practitioners to advance this problem using a combination of human factors engineering and analytical methods.

Understanding Medical Students’ Beliefs On Abortion And Sexual Reproduction, Maria Jarkowiec, Julia B. Frank, Seema Kakar, Gisela Butera

Medicine Faculty Posters and Presentations

Background/Objective: As a controversial topic in American society, abortion occupies a precarious place in medical school curricula. Although medical students believe abortion is a valid and acceptable topic, fewer than 20% of U.S. medical schools offer formal abortion education in either the pre-clinical or clinical years. Only 40% provide abortion lectures during clerkships. According to Association of Professors of Gynecology and Obstetrics student learning objectives, abortion education should be included at a minimum in the third year core clerkship. In the absence of published curricula, health professional schools must develop their own methods to teach the medical aspects of the …

Knowledge, Training And Experience Of Emergency Responders In The Context Of Functional Needs In General Shelters, Athena K. Fannin

Master of Public Health Program Student Publications

Objective: Gathering and analyzing information on experience, training, and professional affiliation of disaster responders who will deal with functional needs clients in general shelters. Methods: The web-based survey administered in June, 2012 to 165 local Medical Reserve Corps (MRC) volunteers and 72 public health workers was part of a larger study designed to assess functional needs flow processes in general shelters. Descriptive statistics and simple logistic regression were used to analyze data.

Results: The response rate was 16.5%. The percent of survey respondents that had any disaster, medical, or functional needs training were approximately 80%, 70%, and 40% respectively. The …

Second Messenger/Signal Transduction Pathways In Major Mood Disorders: Moving From Membrane To Mechanism Of Action, Part Ii: Bipolar Disorder, Mark Niciu, Dawn F. Ionescu, Daniel C. Matthews, Erica M. Richards, Carlos A. Zarate

Psychiatry and Behavioral Sciences Faculty Publications

The etiopathogenesis and treatment of major mood disorders have historically focused on modulation of monoaminergic (serotonin, norepinephrine, dopamine) and amino acid [γ-aminobutyric acid (GABA), glutamate] receptors at the plasma membrane. Although the activation and inhibition of these receptors acutely alter local neurotransmitter levels, their neuropsychiatric effects are not immediately observed. This time lag implicates intracellular neuroplasticity as primary in the mechanism of action of antidepressants and mood stabilizers. The modulation of intracellular second messenger/signal transduction cascades affects neurotrophic pathways that are both necessary and sufficient for monoaminergic and amino acid–based treatments. In this review, we will discuss the evidence in …

Medicine + Health, Fall 2013, George Washington University, School Of Medicine And Health Sciences, Office Of Communications And Marketing

Medicine + Health Magazine

No abstract provided.

Academy Of Nutrition And Dietetics Benchmarks For Nutrition In Child Care 2011: Are Child-Care Providers Across Contexts Meeting Recommendations?, Dipti A. Dev, Brent A. Mcbride, Strong Kids Research Team

Department of Child, Youth, and Family Studies: Faculty Publications

The Academy of Nutrition and Dietetics (Academy) recommends feeding practices for child-care providers to establish nutrition habits in early childhood to prevent obesity. With >12 million US children in child care, little is known about child-care providers’ feeding practices. The purpose of this study was to examine child-care providers’ feeding practices to assess whether providers met the Academy’s benchmarks and whether attainment of benchmarks varied across child-care contexts (Head Start, Child and Adult Care Food Program [CACFP], and non-CACFP). Cross-sectional data was collected in 2011 and 2012 from 118 child-care providers who completed self-administered surveys regarding their feeding practices for …

The Lli Chronicle Volume 4 Number 3, Nova Southeastern University - Shepard Broad College Of Law

Lifelong Learning Institute Newsletters

No abstract provided.

A Dexamethasone Prodrug Reduces The Renal Macrophage Response And Provides Enhanced Resolution Of Established Murine Lupus Nephritis, Fang Yuan, Dana Tabor, Richard K. Nelson, Hongjiang Yuan, Yijia Zhang, Jenny Nuxoll, Kimberly K. Bynote, Subodh M. Lele, Dong Wang, Karen A. Gould

Journal Articles: Pharmaceutical Sciences

We evaluated the ability of a macromolecular prodrug of dexamethasone (P-Dex) to treat lupus nephritis in (NZB × NZW)F1 mice. We also explored the mechanism underlying the anti-inflammatory effects of this prodrug. P-Dex eliminated albuminuria in most (NZB × NZW)F1 mice. Furthermore, P-Dex reduced the incidence of severe nephritis and extended lifespan in these mice. P-Dex treatment also prevented the development of lupus-associated hypertension and vasculitis. Although P-Dex did not reduce serum levels of anti-dsDNA antibodies or glomerular immune complexes, P-Dex reduced macrophage recruitment to the kidney and attenuated tubulointerstitial injury. In contrast to what was observed with free dexamethasone, …

Efinancial Health Synergy And Prevention Science, Nan Taylor

Cornerstone 1 Reports : Expansion and Enhancements of the Thinkfinity Platform

No abstract provided.

Administrative Issues Journal: Table Of Contents

Administrative Issues Journal

No abstract provided.

Tpl2 Kinase Regulates Fcγr Signaling And Immune Thrombocytopenia In Mice, Irene Kyrmizi, Marianna Ioannou, Maria Hatziapostolou, Philip N. Tsichlis, Dimitrios T. Boumpas, Ioannis Tassiulas

NYMC Faculty Publications

The MAPK3 Tpl2 controls innate and adaptive immunity by regulating TLR, TNF-α, and GPCR signaling in a variety of cell types. Its ablation gives rise to an anti-inflammatory phenotype characterized by resistance to LPS-induced endotoxin shock, DSS-induced colitis, and TNF-α-induced IBD. Here, we address the role of Tpl2 in autoimmunity. Our data show that the ablation and the pharmacological inhibition of Tpl2 protect mice from antiplatelet antibody-induced thrombocytopenia, a model of ITP. Thrombocytopenia in this model and in ITP is caused by phagocytosis of platelets opsonized with antiplatelet antibodies and depends on FcγR activation in splenic and hepatic myeloid cells. …

The Proton Problem, Edward C. Halperin

NYMC Faculty Publications

No abstract provided.

The Principles Of Good Health Care In The U.S. In The 2010s, Andrew S. Targowski

Transactions of the International Conference on Health Information Technology Advancement

The purpose of this investigation is to define the principles of good health in the U.S. in the 21st century. The interdisciplinary, civilizational methodology is applied to establish roots of this health care at the national level. Among findings are; well-being of Americans” is the constitutional opportunity of an American, good health of Americans is a constituent of their well-being, basic health care should be perceived as the controlled right of a citizen. Human and societal wisdom requires mentally healthy people. Human and societal wisdom requires well educated citizens. The state of health care of the Americans is in a …

The Pertinence Of Maternal Education On Child Immunization In Rural Uttarakhand: More Than Just Increased Rates, Sarah Banerji

Independent Study Project (ISP) Collection

Child immunization rates in India continue to remain low, despite the 1985 implementation of a Universal Immunization Program that provides free basic immunizations to all children. There are numerous logistical factors that contribute to the low rates of immunization, but rates are made further worse by a lack of parental awareness and education about immunization, especially in village communities. This study examines the maternal understanding of immunization in rural Uttarakhand, both in villages in which an NGO has been working to improve maternal immunization education and in villages with no NGO involvement. It finds a positive correlation between increased immunization …

The Perception Of Maternal Anemia And The Effect Of Nutritional Education: A Qualitative Analysis Among Village Mothers In Rural Kumaon, Uk, Kelsey Bash

Independent Study Project (ISP) Collection

Malnutrition is often associated with starving children in developing countries. However, while calorie and protein deficiencies—macronutrient deficiencies—are a cause for concern, micronutrient deficiencies can be equally detrimental and are even more pervasive. The most prevalent micronutrient deficiency is anemia, and the story of anemia in India is particularly grim. India has the largest number of anemic people in the world and severe anemia is the cause of death for an average of 22,000 Indians each year (The Micronutrient Initiative 2006). Anemia rates are exacerbated for women and even more so for pregnant women. According to the most recent National Family …