Medicine and Health Sciences Commons^™

Identification And Characterization Of The Human Herpesviruses 6a And 6b Genome Integration Into Telomeres Of Human Chromosomes During Latency, Jesse Herbert Arbuckle

USF Tampa Graduate Theses and Dissertations

While the latent genome of most Herpesviruses persists as a nuclear circular episome, previous research has suggested that Human Herpesvirus 6 (HHV-6) may integrate into host cell chromosomes, and be vertically transmitted in the germ-line. Because the HHV-6 genome encodes a perfect TTAGGG telomere repeat array at the right end direct repeat (DR_R) and an imperfect TTAGGG repeat at the end of the left end direct repeat (DR_L), we established a hypothesis that during latency, the HHV-6A and HHV-6B genome integrates into the telomeres of human chromosomes through homologous recombination with the n(TTAGGG) viral repeats, and …

The Natural History Of Human Papillomavirus Related Condyloma In A Multinational Cohort Of Men, Gabriella Anic

USF Tampa Graduate Theses and Dissertations

Human papillomavirus (HPV) is the most common sexually transmitted infection in the United States, but few studies have examined the progression from HPV infection to disease in men. Genital condyloma are the most common clinical manifestation of HPV infection. Though not associated with mortality, condyloma are a source of emotional distress, and treatment is often painful with a high recurrence rate. The aims of this study were to examine the distribution of HPV types present on the surface of condyloma, estimate the incidence of condyloma overall and after type-specific HPV infections, assess the sociodemographic and sexual behavior factors independently associated …

Drug Courts Work, But How? Preliminary Development Of A Measure To Assess Drug Court Structure And Processes, Blake Barrett

USF Tampa Graduate Theses and Dissertations

The high prevalence of substance use disorders is well-documented among criminal offenders. Drug courts are specialty judicial programs designed to: 1) improve public safety outcomes; 2) reduce criminal recidivism and substance abuse among offenders with substance use disorders; and 3) better utilize scarce criminal justice and treatment resources. Drug courts operate through partnerships between the criminal justice, behavioral health and public health systems. Offenders participate in an intensive regimen of substance abuse treatment and case management while under close judicial supervision. Drug courts' effectiveness in reducing criminal recidivism and drug use has been documented through numerous primary studies as well …

An Examination Of The Impact Of Preconception Health On Adverse Pregnancy Outcomes Through The Theoretical Lens Of Reciprocal Determinism, Mary Elizabeth Buie

USF Tampa Graduate Theses and Dissertations

Statement of Purpose

The purpose of this study is to examine the impact of preconception health on adverse pregnancy outcomes through the theoretical lens of reciprocal determinism. Thus, this study aims to develop a preconception health conceptual framework that accounts for the interactive relationships among behavior, the environment, and the person.

Rationale for the Study

Women may not recognize a pregnancy until the first or second missed menstrual cycle, a full four to eight weeks or more after conception. Once a woman realizes the possibility of a pregnancy, it takes further time to confirm the pregnancy with a home pregnancy …

Disparities In Survival And Mortality Among Infants With Congenital Aortic, Pulmonary, And Tricuspid Valve Defects By Maternal Race/Ethnicity And Infant Sex, Colleen Conklin

USF Tampa Graduate Theses and Dissertations

Background: The etiology of congenital heart valve defects is not well understood; little is known about the risk factors that contribute to the survival and mortality outcomes of children with these defects.

Methods: Using data from the Texas Birth Defects Registry (TBDR) we conducted a retrospective cohort study of 2070 singleton infants with congenital aortic, pulmonary, or tricuspid valve atresia or stenosis born in Texas between January 1, 1996 and December 31, 2007 to Hispanic, Non-Hispanic (NH) black, and NH white women. TBDR data were death-to-birth matched by the Texas Vital Statistics Unit for deaths between January 1, 1996 and …

Inhibition Of P53 Dna Binding Function By The Mdm2 Acidic Domain, Brittany Lynne Cross

USF Tampa Graduate Theses and Dissertations

MDM2 regulates p53 predominantly by promoting p53 ubiquitination. However, ubiquitination-independent mechanisms of MDM2 have also been implicated. Here we show that MDM2 inhibits p53 DNA binding activity in vitro and in vivo. MDM2 binding promotes p53 to adopt a mutant-like conformation, losing reactivity to antibody Pab1620, while exposing the Pab240 epitope. The acidic domain of MDM2 is required to induce p53 conformational change and inhibit p53 DNA binding. ARF binding to the MDM2 acidic domain restores p53 wild type conformation and rescues DNA binding activity. Furthermore, histone methyl transferase SUV39H1 binding to the MDM2 acidic domain also restores p53 wild …

Adolescence Is An Ocean: A Biocultural Investigation Of Youth Food Consumption In Tanzania, Elizabeth J. Danforth

USF Tampa Graduate Theses and Dissertations

This study investigates adolescents' relationships with food and other community and household members' perceptions of youth and their food consumption to understand the multifactorial dynamic processes which create nutritional outcomes among urban and rural youth in central Tanzania. Youth are an important and demographically large population in developing countries. The identities created during this distinct stage of cultural production can be reflected in youths' food consumption and relationships with food. Nutrition likely affects how youth transition through a variety of states, including their growth and development stages, primary to secondary to higher education, child to parent, or unemployed to employed. …

Apparent Total Evaporative Resistance Values From Human Trials Over A Range Of Metabolic And Heat Stress Levels, Matthew David Dooris

USF Tampa Graduate Theses and Dissertations

Failure to maintain thermal equilibrium can cause uncontrollable increases in body core temperature beyond critical upper limits. In selecting clothing, consideration must be given to the heat transfer properties of clothing that may restrict the cooling capacity of the human body under heat stress conditions, most importantly, apparent total evaporative resistance (R_e,T,_a). This study calculated and compared R_e,T,_a for five clothing ensembles under varying heat stress conditions, including three relative humidity (RH) levels and three stages of heat stress to determine if R_e,T,_a values varied or remained the same with …

Cement Pulmonary Embolism: A Common And Potentially Serious Complication Of Vertebroplasty, Brigid Hallinan Do, Yehia Y. Mishriki Md

Department of Medicine

No abstract provided.

Atypical Lymphocytic Lobular Panniculitis: A Distinct Eentity In The Spectrum Of Cutaneous Lymphoid Dyscrasia, Lusia S. Yi Do, Ms, Nicole Bright Do, Stephen Purcell Do

Department of Medicine

No abstract provided.

Call-Fleming Syndrome: More Than A Crazy Migraine, Erin M. Conahan Rn, Cnrn, Claranne Mathiesen Rn, Msn, Cnrn

Department of Medicine

No abstract provided.

Community Cancer Services, Clinical Trials, And Quality Initiatives—Year 1 Ncccp At Lehigh Valley Health Network, Gregory R. Harper Md, Phd, Ada M. Rivera Ba, Eliot L. Friedman Md, Kathleen A. Leies Rn, Ocn, Nadesda Mack Rn, Bsn, Mba, Ocn, Lenore Mcgonigle Med, Suresh G. Nair Md, Tara Namey Ms, Cgc, Debbie Salas-Lopez Md, Mph, Facp, Ronald W. Swinfard Md, Facp

Department of Medicine

No abstract provided.

Clinical Practice Guidelines For Rehab And Oncology, Stephanie L. Marshall Pt, Dpt, Ocs, Kathleen A. Leies Rn, Jennifer Roeder Mspt, Mba

Department of Medicine

No abstract provided.

Comparative Prognostic Significance Of Sentinel Lymph Node Biopsy And Axillary Lymphadenectomy In Carcinoma Of The Breast, Aaron D. Bleznak Md, Facs, Jennifer Bleznak, Barbara Gutch Rn, Aileen Galley Msw

Department of Medicine

No abstract provided.

Equestrian Perniosis, Donald J. Adler Do, Marie S. Lewars Do

Department of Medicine

No abstract provided.

En Coup De Sabre, Marie S. Lewars Do, Gwyn Frambach Do, Charles Grooper Md

Department of Medicine

No abstract provided.

Esta En Sus Manos! It’S In Your Hands!, Lenore Mcgonigle Med, Vanessa Soto, Hannabi Torres, Heiwon Chung Md, Facs, Nadesda Mack Rn, Bsn, Mba, Ocn, Renae Stonehouse Rt, (R), (M), Maryellen Shiels Bs

Department of Medicine

No abstract provided.

From The Home To The Hospital: The New Bath Salts, Jeanne Zukas Do, Matthew D. Cook Do

Department of Medicine

No abstract provided.

Giant Cell Arteritis Presenting With Bilateral Axillary Artery Occlusions, Vertebral Artery Stenosis And Left Internal Mammary Artery Graft Stenosis, Rashmi Sharma Md, J Patrick Kleaveland Md, Marie S. O’Brien Do

Department of Medicine

No abstract provided.

In Our Own Backyard, Jeanne L. Zukas Do, Suzanne J. Templer Do

Department of Medicine

No abstract provided.

Interdisciplinary Care Approach In The Neuroscience Intensive Care Unit And It’S Effect On Early Mobilization, Kamille J. Sprenkle Pt, Dpt, Maureen T. Smith Rn, Msn, Cnrn

Department of Medicine

No abstract provided.

Oral Fixed Drug Eruption Secondary To Isoniazid, Tanya Ermolovich Do, Tatyana Groysman Do

Department of Medicine

No abstract provided.

Improving Symptoms Of Stress Urinary Incontinence For Patients With Dyspareunia Utilizing Physical Therapy: A Case Report, Karen Snowden Pt, Dpt, Lauren Garges Pt, Ms

Department of Medicine

No abstract provided.

Improving The Quality Of Information Sent To Primary Care Physicians For Patients Discharged From Nursing Facilities, Catherine M. Glew Bm, Bs, Cmd, Anne M. Yawman Md

Department of Medicine

No abstract provided.

Neo-Adjuvant Chemotherapy And Radiation Therapy In Patients With Stage Iiia (N2) Non-Small Cell Lung Cancer (Nsclc): A Retrospective Analysis With Lessons Learned, Eliot L. Friedman Md, Michael F. Szwerc Md, Charles Andrews Md, Robert Kruklitis Md, Kathleen A. Leies, Ferdy Santiago

Department of Medicine

No abstract provided.

Plexiform Neurofibroma Associated With Nf1, Stephen M. Purcell Do, Tatyana Groysman Do

Department of Medicine

No abstract provided.

Progressive Symmetric Erythrokeratoderma, Sevasti Margetas Do, Stephen Purcell Do

Department of Medicine

No abstract provided.

The Use Of Interval Division Of Education In The Navigation Of Breast Cancer Patients, Jane Zubia Rn, Ocn, Cbpn I-C, Laura Beaupre Bsn, Ocn, Cbpn-Ic, Diane Mchugh Bsn, Ocn, Cbpn-Ic, Raizalie Roman-Rosado Bsn, Ocn, Cmsrn, Nadesda Mack Rn, Bsn, Mba, Ocn

Department of Medicine

No abstract provided.

Pseudo-Cushing’S Syndrome In A Hiv Patient With Complete Resolution Following Discontinuation Of Darunavir/Ritonavir, Rashmi Sharma Md, Margaret Hoffman-Terry Md, Facp

Department of Medicine

No abstract provided.

Unusual Case Of Thrombotic Thrombocytopenic Purpura (Ttp) In Capnocytophaga Canimorsus Bacteremia, Nicole W. Tong Do

Department of Medicine

No abstract provided.