Medicine and Health Sciences Commons^™

The Effect Of Pre-Operative Rehabilitation In High Risk Open Heart Surgery Patients On The Length Of Hospital Stay, Wen-Chih Lin, Yi-Ru Chen, Chiao-Hsin Chen, Shu-Han Yang, Chin-Tsan Huang, Mei-Yi Wu, Willy Chou

Rehabilitation Practice and Science

The study was to evaluate the effect of pre-operative education for diaphragmatic breathing and coughing techniques in elective open heart surgery patients on the post-operative pulmonary complications, ventilator use duration and post-operative hospital days.The retrospective chart reviewarticle of the 27 elective open heart surgery patients was from March 2008 to April 2009. The basic data and risk factors of post-operative complications were recorded. The complications, mechanical ventilation duration, and hospital days in the two groups with and without the education were compared; so were the high risk and nonhigh risk group according to the risk score of the post-operative pulmonary …

Oxygen Uptake Efficiency Slope Before And After Weight Reduction Program In Obese Adults, Chueh-Hung Wu, Shu-Ming Yeh, Ke-Vin Chang, Hung-Pin Lee, Ssu-Yuan Chen, Ching Lan, Hung-Chih Tsai, Ya-Ling Huang, Jin-Shin Lai

Rehabilitation Practice and Science

Background and Purpose: Oxygen uptake efficiency slope (OUES) is an index for evaluating cardiorespiratory fitness without performing maximal exercise and correlates well with the individual's peak oxygen uptake (□O(superscript 2peak)). The purpose of this study was to determine the clinical usefulness of OUES for determining the cardiorespiratory fitness of obese adults without cardiovascular diseases by investigating (1) the correlation between OUES and weight (2) the change in the OUES after a weight-reduction program. Methods: Fifty-eight obese subjects (13men and 45women) were enrolled in a 12-week weight-reduction program, including diet, exercise and psychological programs. They underwent maximal cycle ergometer exercise testing, …

T12 Compression Fracture Complicated With Delayed Spinal Epidural Hematoma: A Casereport, Chia-Wei Wu, Ching-Shiang Tseng, Lin-Fen Hsieh

Rehabilitation Practice and Science

Delayed spinal epidural hematoma (SEH) after a spinal compression fracture is a very rare but important cause of symptomatic spinal cord compression. We report a patient with spinal cord compression and cauda equina syndrome due to delayed SEH after a traumatic T12 compression fracture. A 74-year-old male patient had severe back pain without neurologic deficits after a traumatic T12 compression fracture. He developed progressive bilateral lower extremity weakness, sensory loss, and sphincter dysfunction 2.5 months after the injury. Magnetic resonance imaging of the spine revealed a huge spinal epidural hematoma at the level of T12 to L5. He then received …

Tetraplegia Caused By Critical Illness Polyneuropathy Superimposed On Diabetic Neuropathy: A Casereport, Chia-Chen Li, Shih-Fu Hsieh, Ming-Chuan Lin, Chung-Wei Huang, Yi-Shiung Horng

Rehabilitation Practice and Science

Objective: To describe a patient with the critical illness polyneuropathy superimposed on diabetic neuropathy and to highlight the importance of early rehabilitation after critical illness. Methods: A 42-year-old man with a previous history of diabetic polyneuropathy developed flaccid tetraplegia with respiratory failure after septic shock due to a liver abscess. This clinical manifestation, combined with the result of an electrodiagnostic study, suggested the acute exacerbation of polyneuropathy. Because a pre-existing polyneuropathy history complicated a differential diagnosis, we performed a comprehensive work-up to rule out other systemic diseases or metabolic disorders that may cause polyneuropathy. Finally, the diagnosis of critical illness …

Acute Paraplegia After Spinal Manipulation: A Casereport, Kao-Chih Chen, Yao-Jen Chen

Rehabilitation Practice and Science

This is a casereport about a 53-year-old female patient with a history of chronic back pain, suffered from complete paraplegia shortly after spinal manipulation. CT and MRI images consistently showed ossification of the ligamenta flava in conjunction with bilateral facet joints hypertrophy at the T10-11, T11-12 and L1-2 levels. Spinal cord injury with T12 paraplegia ASIA-A was thus diagnosed. Posterior laminectomy at the T10, T11, L1 and L2 levels and interbody fusion from T10 to L2 spines for fixation were performed. After rehabilitation, the patient regained some activities of daily living despite complete paraplegia. To raise public awareness, our report …

Cerebral Venous Thrombosis With Cerebral Arterial Infarction During Pregnancy: A Casereport, Shih-I Huang, Tien-Wen Chen, Mao-Hsiung Huang

Rehabilitation Practice and Science

Cerebral venous thrombosis (CVT) usually occurs in young adult or middle aged adult women. Although not of high incidence, it is an important cause of brain hemorrhage or infarction in pregnant women. According to previous studies, the most common symptom is headache. However, because of only headache mostly, correct diagnosis is a challenge before progression to stroke. The patient was a 30-year-old female. Except for hyperthyroidism history during last pregnancy, she did not have any special associated past history. She suffered sudden onset of left side weakness; when her term was 32 weeks. Brain magnetic resonance imaging showed right middle …

Serotonin Syndrome In Acute Transverse Myelitis: A Casereport, Pei-Chun Hsieh, Jo-Tong Chen, Ta-Shen Kuan, Shu-Min Chen

Rehabilitation Practice and Science

Numerous serotonergic drugs have been increasingly used in recent years to treat depression, pain, insomnia and obesity. However, concomitant use of these drugs may cause serotonin syndrome. The three main clinical features of serotonin syndrome are neuromuscular abnormalities, autonomic hyperactivity, and mental status changes. A wide variety of the clinical presentations range from: very mild symptoms such as tremor, diarrhea, muscle rigidity, or clonus, and hyperreflexia; to fatal consequences such as disseminated intravascular coagulation or multiple-organ failure. Symptoms resolve spontaneously after prompt discontinuation of the precipitating medication. The diagnosis is based on clinical presentation, history of medication, and resolution after …

Development Of Brain Abscess At The Exact Site Of A Previous Intracerebral Hematoma: A Casereport, Yi-Yen Chu, Shu-Huan Lin, Tyng-Guey Wang

Rehabilitation Practice and Science

Brain abscess is a neurological emergency that requires immediate high-dose antibiotics or surgical intervention. Brain abscess at the site of a previous hemorrhagic stroke that did not receive surgical intervention is rare. Here, we report the case of a 48-year-old man who developed a brain abscess as infective transformation of a preceding right putaminal hemorrhage, 22 days after the stroke. The patient recovered after surgical treatment and systemic antibiotics therapy. An abscess culture test revealed the presence of Group D Salmonella, which has never been reported in a case of brain abscess. A comprehensive literature reviewarticle was performed. We concluded …

Macrodystrophia Lipomatosa: A Casereport, Pai-Yin Chen, Shu-Min Chen, Chii-Jeng Lin

Rehabilitation Practice and Science

Macrodystrophia lipomatosa is a rare congenital anomaly of localized gigantism, characterized by progressive overgrowth of all mesenchymal components, particularly fibroadipose tissue. The anomaly occurs frequently in the distribution regions of the median nerve in the upper extremity and the plantar nerve in the lower extremity. It is usually noticed at birth with predominately unilateral distal involvement of the digits. The cause of this condition is still unknown. Physicians use the patient's clinical history, physical examination, and imaging techniques to diagnose the condition, with characteristic imaging findings revealing macrodactyly with hypertrophy of the soft tissue and osseous structures. This study reports …

Wrist Schwannoma Mimicking De Quervain's Disease: A Casereport, Pon-An Chen, Chung-Liang Lai, Ming-Miau Tsai, Chuan-Chin Leu, Tyng-Guey Wang

Rehabilitation Practice and Science

For decades, ultrasonography has shown a high degree of accuracy in the evaluation of soft tissue tumors. In this study, we report the condition of a 80-year-old male patient who had been suffering from left thumb pain for 2 years. The patient had initially been diagnosed with de Quervain's disease, but responded poorly to conservative treatment. An ultrasonographic examination unexpectedly identified a well-margined solid tumor with marked vascularity. Suspicion of a neurogenic tumor led to an excision surgery and finally pathology revealed a Schwannoma. Following excision, the symptoms were entirely ameliorated. We concluded that, in the evaluation of persistent chronic …

Panuveitis After Intravenous Injection Of Bisphosphonate: A Casereport, Chi-Kai You, Si-Huei Lee, Chen-Liang Chou

Rehabilitation Practice and Science

As human life expectancy has increased, osteoporosis has become a major epidemic disorder. The most common consequences of this are fractures in different parts of the body. In addition to regular follow-up tests of bone-mineral density, treatment methods include: 1. increasing the dietary intake of calcium and vitamin D, 2. maintenance of body weight, avoiding alcohol and tobacco, regular exercise, and fall prevention, 3. medications, the most widely used being bisphosphonates. Bisphosphonates can limit bone loss via the inhibition of osteoclasts. They have been widely prescribed for senile osteoporosis, osteoporosis due to administration of steroids, bone loss due to malignancies …

Partition Decoupling For Multi-Gene Analysis Of Gene Expression Profiling Data, Rosemary Braun, Gregory Leibon, Scott Pauls, Daniel Rockmore

Dartmouth Scholarship

Background:

Multi-gene interactions likely play an important role in the development of complex phenotypes, and relationships between interacting genes pose a challenging statistical problem in microarray analysis, since the genes involved in these interactions may not exhibit marginal differential expression. As a result, it is necessary to develop tools that can identify sets of interacting genes that discriminate phenotypes without requiring that the classification boundary between phenotypes be convex.

Results:

We describe an extension and application of a new unsupervised statistical learning technique, known as the Partition Decoupling Method (PDM), to gene expression microarray data. This method may be used …

Prevalence And Risk Factors Of Major Depressive Disorder In Hiv/Aids As Seen In Semi-Urban Entebbe District, Uganda, Eugene Kinyanda, Susan Hoskins, Juliet Nakku, Saira Nawaz, Vikram Patel

Dartmouth Scholarship

Background:

Not much is known about the risk factors of major depressive disorder (MDD) in HIV/AIDS in the African socio-cultural context. Therefore a study was undertaken to examine the prevalence and risk factors of MDD in HIV/AIDS in semi-urban Uganda.

Methods:

A cross-sectional study was undertaken among 618 respondents attending two HIV clinics in Uganda.

Results:

Prevalence of MDD was 8.1%. Factors associated with MDD at univariate analysis only were female gender, family history of mental illness, negative coping style, alcohol dependency disorder, food insecurity and stress; not associated with MDD were social support, neurocognitive impairment, CD4 counts and BMI. …

Functional Evaluation Of The Urinary Tract By Duplex Doppler Ultrasonography In Patients With Acute Renal Colic., Raza Sayani, Muhammad Ali, Kashif Shazlee, Rana Shoaib Hamid, Kamran Hamid

Department of Radiology

Purpose: To determine the role of duplex Doppler ultrasonography (DDU) in Patients with acute unilateral renal obstruction. Subjects And Methods:A total of 161 Patients with suspected renal colic due to urolithiasis were evaluated by DDU followed by intravenous urography (IVU). The mean intra-arterial resistive index (RI) and the difference of mean resistive index between both kidneys (delta RI) were determined for each person. An RI value of ≥0.70 and a delta RI value of ≥0.06 were taken as the discriminatory threshold for obstruction. IVU results were considered the " reference standard" against which renal DDU findings were compared.

Results: …

Pengaruh Pemberian Kombinasi Ekstrak Air Akar Kucing (Acalypha Indica Linn.) Dengan Ekstrak Etanol 70% Rimpang Jahe Merah (Zingiber Officinale Rosc.) Terhadap Penurunan Kadar Asam Urat Tikus Putih, Anita Ayu Dwi Ajie Saputri, Juheini Amin, Azizahwati Azizahwati

Majalah Ilmu Kefarmasian

Hyperuricemia treatment can be given roots of Acalypha indica Linn. Combined with red ginger plant (Zingiber officinale Rosc.) as anti-inflammatory drug. This study aimed to examine the effect of aqueous extract the roots of Acalypha indica Linn. with 70%ethanol extract of rhizome of Red Ginger from the decrease in blood uric acid levels of male rats made hiperurisemia by potassium oxonate. There were 35 male white rats of Sprague Dawley strain weighing 180 g to 200 gs were divided into seven groups. Three groups were given a combination of extract, consist of a fixed dose 5.4 g/200 g bb of …

Optimasi Kecepatan Disintegrasi Tablet Terdisintegrasi Cepat (Fast Disintegrating Tablet) Domperidon Dengan Superdisintegran Sodium Starch Glycolate, Imam Prabowo, Iskandarsyah Iskandarsyah

Majalah Ilmu Kefarmasian

Fast disintegrating tablet is one of advanced pharmaceutical technologies. Fast disintegrating tablets is a tablet when placed on the tongue will be instantly disintegrated and releases the drug with the help of saliva. This technology can solve the problem of using oral drug in patients such as pediatrics, geriatrics or in circumstances where the patient can not swallow tablets conventionally with the help of water. The purpose of this study was to optimize the speed of disintegration in fast disintegrating tablet formulations both with varying concentrations of sodium starch glycolate. Optimization the speed of disintegration was done by using sodium …

Earlier Surgical Intervention In Congenital Heart Disease Results In Better Outcome And Resource Utilization, Roheena Z. Panni, Awais Ashfaq, Muhammad M. Amanullah

Section of Cardiothoracic Surgery

Background:Congenital heart disease (CHD) accounts for a major proportion of disease in the pediatric age group. The objective of the study was to estimate the cost of illness associated with CHD pre, intra and postoperatively, among Patients referred to a tertiary care hospital in Karachi, Pakistan. This is the first study conducted to estimate the cost of managing CHD in Pakistan.

Methods:

A prevalence based cost of illness Study Design was used to estimate the cost of cardiac surgery (corrective & palliative) for congenital heart defects in children Results:The mean age at the time of surgery in group …

Determinants Of Prostate Survival In Arizona: Demographic And Clinical Characteristics, Gudeta D. Fufaa

Journal of Social, Behavioral, and Health Sciences

In investigating the determinants of survival of prostate cancer cohorts, characterization of the cohort in terms of competing underlying causes of death would be appropriate. Atherosclerotic heart disease, bronchitis, acute myocardial infarction, chronic obstructive pulmonary disease, atherosclerotic cardiovascular disease, and stroke were found to be the major causes of death among prostate cancer cohorts aside from prostate cancer. A population-based assessment of the codeterminants of mortality and a demographic and clinical determinant of prostate cancer survival was undertaken. Average survival time and survival curves of the various age categories were significantly different. The average survival time and survival curves of …

Correlation Of Cough Frequency With Treatment Efficacy In Pulmonary Tuberculosis Patients In Lima, Peru, Jesus Gutierrez

Master's Theses

No abstract provided.

Cd2ap Regulates Sumoylation Of Cin85 In Podocytes, Irini Tossidou, Rainer Niedenthal, Malte Klaus, Beina Teng, Kirstin Worthmann, Benjamin King, Kevin Peterson

Dartmouth Scholarship

Podocytes are highly differentiated and polarized epithelial cells located on the visceral side of the glomerulus. They form an indispensable component of the glomerular filter, the slit diaphragm, formed by several transmembrane proteins and adaptor molecules. Disruption of the slit diaphragm can lead to massive proteinuria and nephrotic syndrome in mice and humans. CD2AP is an adaptor protein that is important for the maintenance of the slit diaphragm. Together with its paralogue, CIN85, CD2AP belongs to a family of adaptor proteins that are primarily described as being involved in endocytosis and downregulation of receptor tyrosine kinase activity. We have shown …

Research Brief: "Secondary Trauma And Military Veteran Caregivers", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

This brief is about the stress that occurs for caregivers of veterans due to secondary trauma. In policy and practice, caregivers can continuously monitor themselves for symptoms of secondary trauma, maintain a balance between professional life and personal life, and promote a supportive culture within the caregiver community; policies should acknowledge that secondary trauma stressors do exist for caregivers and should look for ways to reduce the negative effects of secondary trauma stressors. Suggestions for future research include using econometric models to detect relevant factors for risk of developing secondary trauma stressors.

A Critical Analysis Of The Current State Of Neurosurgery Training In Pakistan, Muhammad Shahzad Shamim, Muhammad Zubair Tahir, Saniya Siraj Godil, Rajesh Kumar, Arshad Ali Siddiqui

Section of Neurosurgery

Objective: To observe interdepartmental variation in the availability of resources and academic activities within the various neurosurgery programs of Pakistan.
Methods: This was a proforma-based survey of neurosurgery trainees and young neurosurgeons of Pakistan, looking at the academic infrastructure and output of their programs. The proforma was filled by 36 respondents from 11 neurosurgery centers of the country. All these centers were accredited for neurosurgery training in Pakistan.
Results: Out of the 36 respondents, 30 were completing a Fellowship training (FCPS) and six were enrolled for a Master in Surgery (MS) program. About 80% of the participants used the Youman's …

Pengetahuan Klien Dan Kualitas Pelayanan Sebagai Dasar Pemilihan Alat Kontrasepsi Hormonal, Najib Najib

Kesmas

Tingkat pemakaian kontrasepsi hormonal oleh akseptor Keluarga Berencana di kelurahan Muktiharjo Kidul kota Semarang yang tinggi diduga merupakan dampak tidak diberikannya informasi yang luas tentang kelebihan dan kekurangan alat kontrasepsi dan pelayanan kontrasepsi yang berkualitas. Penelitian ini bertujuan untuk mengetahui hubungan pengetahuan dan kualitas pelayanan dengan pemilihan alat kontrasepsi hormonal pada pasangan usia subur di kelurahan Muktiharjo Kidul. Jenis penelitian adalah explanatory study dengan pendekatan cross sectional yang dianalisis secara deskriptif. Penarikan sampel dilakukan secara acak dari populasi pasangan usia subur yang menggunakan alat kontrasepsi di kelurahan Muktiharjo Kidul kota Semarang. Hasil penelitian menunjukkan bahwa prevalensi pasangan usia subur yang …

Karakteristik Sosial Ekonomi Dan Kesehatan Maternal, Rindang Ekawati

Kesmas

Kesehatan maternal yang tergolong tinggi di Indonesia merupakan indikator keberhasilan pembangunan pada Millenium Development Goals yang terus diupayakan untuk diperbaiki. Penelitian ini bertujuan mengetahui hubungan antara karakteristik sosial, demografi, dan ekonomi dengan tingkat kesehatan ibu. Penelitian yang menggunakan sumber data sekunder Survei Demografi Kesehatan di Jawa Barat yang mencakup 86 blok sensus yang meliputi 2.150 rumah tangga meliputi 1.100 rumah tangga di perkotaan dan 1.050 rumah tangga di pedesaan. Jumlah sampel terpilih adalah 1.720 wanita pernah kawin berumur 15 – 49 tahun. Analisis data dilakukan secara deskriptif analitik dan uji kai kuadrat. Terdapat hubungan signifikan antara umur ibu, pendidikan ibu, …

Defisiensi Riboflavin Dan Demensia Pada Usia Lanjut, Idral Purnakarya

Kesmas

Demensia Alzheimer menempati urutan kesembilan penyebab kematian di Amerika Serikat. Demensia adalah kondisi yang sering dialami yang berhubungan dengan berbagai faktor dan gaya hidup terutama diet. Penelitian ini bertujuan untuk mengetahui hubungan defisiensi asupan riboflavin (vitamin B12) dengan demensia pada usia lanjut (usila). Penelitian ini menggunakan desain studi cross sectional dan dilaksanakan pada bulan September 2007 sampai dengan Januari 2008. Sampel penelitian adalah 141 lansia berumur lebih dari sama dengan 60 tahun yang diambil secara purposive sampling. Demensia diukur menggunakan kuesioner MMSE (² 24, skor maksimum 30) dan asupan riboflavin diukur menggunakan form Semi Quantitative – FFQ. Penelitian ini memperlihatkan …

Obesitas Pada Pekerja Minyak Dan Gas, Dilla Christina, Ratu Ayu Dewi Sartika

Kesmas

Beberapa tahun terakhir angka obesitas di Indonesia cenderung meningkat. Obesitas terjadi akibat ketidakseimbangan antara asupan dan output energi dalam jangka waktu cukup lama. Tujuan penelitian ini adalah untuk mengetahui faktor risiko kejadian obesitas pada pekerja on shore di perusahaan minyak dan gas. Desain penelitian ini adalah studi cross sectional. Sampel yang diteliti adalah seluruh pekerja on shore (laki-laki maupun perempuan) berusia 35 – 55 tahun yang sesuai dan memenuhi kriteria inklusi dan ekslusi yang telah ditetapkan (n = 378). Hasil penelitian menunjukkan bahwa prevalensi obesitas (IMT ³ 25 kg/m2) pada pekerja on-shore sebesar 49,5%. Variabel umur, tingkat pendidikan, status pegawai, …

Tingkat Fertilitas Di Provinsi Nusa Tenggara Timur Dan Yogyakarta, Rahmadewi Rahmadewi, Leli Asih

Kesmas

Provinsi Nusa Tenggara Timur (NTT) memiliki Total Fertility Rate (TFR) tertinggi (4,2 anak) dan yang terendah adalah Provinsi Yogyakarta (1,8 anak). Tujuan penelitian ini adalah mengidentifikasi faktor-faktor yang berhubungan dengan angka fertilitas total di kedua provinsi tersebut. Penelitian ini menggunakan metode kuantitatif berdasarkan sumber data sekunder berbagai survei meliputi Survei Demografi Kesehatan Indonesia (1991-2007); Survei Kesehatan Nasional dan Survei Kesehatan Rumah Tangga tahun 2003; dan Mini Survei tahun 2007 dan 2008. Metode kualitatif dilakukan dengan diskusi kelompok terarah pada wanita pasangan usia subur (PUS) dan wawancara mendalam dengan pengelola program di kabupaten/ kota hingga ke desa/kelurahan. Ditemukan TFR di Yogyakarta …

Instrumen Pengukuran Kualitas Hidup Anak Terinfeksi Hiv, Toha Muhaimin, Budi Utomo, Dharmayati B. Utoyo, Nia Kurniati, Triyanti Anugrahini, Enny Zuliatie

Kesmas

Anak penderita Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome (HIV/AIDS) di Indonesia memperlihatkan tren yang semakin meningkat karena meningkatnya proporsi perempuan terinfeksi HIV/AIDS. Pertimbangan pada dampak besar yang dihadapi anak penderita HIV mendorong kebutuhan pengembangan instrumen khusus untuk mengukur kualitas hidup mereka. Penelitian ini bertujuan mengembangkan instrumen kualitas hidup anak penderita AIDS dengan memodifikasi instrumen yang ada sesuai dengan konteks Indonesia. Pada penelitian ini ditemukan hasil bahwa instrumen yang dikembangkan mempunyai reliabilitas yang cukup baik pada balita dan anak usia 5 – 11 tahun. Nilai reliabilitas (Cronbach’s Alpha) balita, domain fungsi fisik, fungsi sosial, dan gejala HIV masing masing adalah 0,71; …

Kualitas Pelayanan Keluarga Berencana Dan Penggantian Kontrasepsi Di Indonesia, Mugia Bayu Rahardja

Kesmas

Keberhasilan program Keluarga Berencana Nasional tidak hanya diukur dari peningkatan peserta program, tetapi juga efektivitas dan durasi pemakaian kontrasepsi. Penelitian ini bertujuan menilai pengaruh kualitas pelayanan KB terhadap perilaku penggantian alat kontrasepsi di Indonesia. Penelitian sumber data sekunder histori pemakaian metode kontrasepsi dalam kalender data SDKI tahun 2007 dengan metode analisis regresi logistik dengan efek random. Wanita tanpa informed choice dan tanpa kunjungan petugas KB serta pengguna susuk KB berhenti karena ingin metode lebih efektif yang dapat membuat terlihat lebih muda, dan menghasilkan anak sedikit. Pada pasangan yang masa perkawinannya kurang dari 10 tahun, status pendidikan dan sosial ekonomi tinggi, …

High Fat Diet Enhances Cardiac Abnormalities In Shr Rats: Protective Role Of Heme Oxygenaseadiponectin Axis, Jian Cao, Komal Sodhi, Nitin Puri, Sumit R. Monu, Rita Rezzani, Nader G. Abraham

Pharmaceutical Science and Research

Background

High dietary fat intake is a major risk factor for development of cardiovascular and metabolic dysfunction including obesity, cardiomyopathy and hypertension.

Methods

The present study was designed to examine effect of high fat (HF) diet on cardio-vascular structure and function in spontaneously hypertensive rats (SHR), fed HF diet for 15 weeks, a phenotype designed to mimic metabolic syndrome.

Results

Development of metabolic syndrome like phenotype was confirmed using parameters, including body weight, total cholesterol and blood pressure levels. High fat diet impaired vascular relaxation by acetylcholine and exacerbated cardiac dysfunction in SHRs as evidenced by lower left ventricular function, …