Medicine and Health Sciences Commons^™

Thirdhand Tobacco Smoke: Emerging Evidence And Arguments For A Multidisciplinary Research Agenda, Georg E. Matt, Penelope J. Quintana, Hugo Destaillats, Lara A. Gundel, Mohamad Sleiman, Brett C. Singer, Peyton Jacob, Jonathan P. Winickoff, Prue Talbot, Suzaynn Schick, Yinsheng Wang, Bo Hang, Manuela Martins-Green, James F. Pankow, Melbourne F. Hovell, Neal L. Benowitz, Virender K. Rehan, Jonathan M. Samet

Civil and Environmental Engineering Faculty Publications and Presentations

There is broad consensus regarding the health impact of tobacco use and secondhand smoke exposure, yet considerable ambiguity exists about the nature and consequences of thirdhand smoke (THS). We introduce definitions of THS and THS exposure and review recent findings about constituents, indoor sorption-desorption dynamics, and transformations of THS; distribution and persistence of THS in residential settings; implications for pathways of exposure; potential clinical significance and health effects; and behavioral and policy issues that affect and are affected by THS. Physical and chemical transformations of tobacco smoke pollutants take place over time scales ranging from seconds to months and include …

Dynamic Alteration Of Adiponectin/Adiponectin Receptor Expression And Its Impact On Myocardial Ischemia/Reperfusion In Type 1 Diabetic Mice., Yanzhuo Ma, Yi Liu, Shaowei Liu, Yan Qu, Rutao Wang, Chenhai Xia, Haifeng Pei, Kun Lian, Tao Yin, Xiaoyan Lu, Lu Sun, Lu Yang, Yanjie Cao, Wayne Bond Lau, Erhe Gao, Haichang Wang, Ling Tao

Department of Emergency Medicine Faculty Papers

The present study determined the dynamic change of adiponectin (APN, a cardioprotective adipokine), its receptor expression, and their impact upon myocardial ischemia/reperfusion (MI/R) injury during type 1 diabetes mellitus (T1DM) progression, and involved underlying mechanisms. Diabetic state was induced in mice via multiple intraperitoneal injections of low-dose streptozotocin. The dynamic change of plasma APN concentration and cardiac APN receptor-1 and -2 (AdipoR1/2) expression were assessed immediately after diabetes onset (0 wk) and 1, 3, 5, and 7 wk thereafter. Indicators of MI/R injury (infarct size, apoptosis, and LDH release) were determined at 0, 1, and 7 wk of DM duration. …

Tailoring A Treatment Fidelity Framework For An Intensive Care Unit Clinical Trial, Linda L. Chlan, Jill L. Guttormson, Kay Savik

College of Nursing Faculty Research and Publications

Background:

Treatment fidelity (TF) refers to methodological strategies and practices used to monitor and enhance the reliability and validity of behavioral interventions. Treatment fidelity monitoring enhances internal and external validity and is needed for study replication and generalizability.

Objectives:

The aim of this study was to describe the implementation, monitoring, and impact of TF in an intensive-care-unit-based clinical trial testing music for anxiety self-management with mechanically ventilated patients.

Method:

Development of the criteria was based on the Five-Component Treatment Fidelity Framework from the Treatment Fidelity Workgroup. Descriptive statistics were used to evaluate adherence rates to the key TF criteria and …

Testing The Integrated Theory Of Health Behaviour Change For Postpartum Weight Management, Polly Ryan, Marianne E. Weiss, Nicole Traxel, Michael J. Brondino

College of Nursing Faculty Research and Publications

Aim.  This is a report of a correlational study to test the Integrated Theory of Health Behaviour Change within the context of postpartum weight self‐management including the impact of race/ethnicity and weight classification.

Background.  Women experiencing childbirth face increasing challenges to manage their weight postpartum. Little is known about women’s weight self‐management during the complex physiological and psychosocial transition of the postpartum period.

Methods.  Data were collected during the birth hospitalization and 4 months postbirth during 2005 and 2006. A quota sample of 250 postpartum women using two strata, race/ethnicity and prepregnant weight classification, were enrolled; 179 women completed the …

Autism Spectrum Disorder: Parenting Stress, Family Functioning And Health-Related Quality Of Life, Norah L. Johnson, Marilyn Frenn, Suzanne Feetham, Pippa Simpson

College of Nursing Faculty Research and Publications

The prevalence of Autism Spectrum Disorder (ASD) is 1 in 110 persons in the U.S. Both parents of children with ASD are under stress that may impact their health-related quality of life (HRQL) (physical and mental health). The purpose of the current study was to explore the relationship of parenting stress, support from family functioning and the HRQL (physical and mental health) of both parents. Female (n = 64) and male (n = 64) parents of children with ASD completed Web-based surveys examining parenting stress, family functioning, and physical and mental health. Results of a Wilcoxon signed-ranks test showed that …

Legal Aspects Of Aerobic Capacity: Objective Evidence Of The Ability To Work, Margaret E. Ciccolella, Tommy Boone, Todd E. Davenport

School of Pharmacy Faculty Articles

The article discusses the legality of aerobic capacity testing in disability cases particularly chronic fatigue syndrome (CFS). It says that aerobic capacity testing can be used to document functional impairments in patients with CFS after the failure of Functional Capacity Evaluation (FCE) in evaluating the ability to work of CFS patients who claim for insurance benefits. It presents case law reviews that illustrate the importance of expert testimony in disability related insurance benefit.

Re-Design For The Time: Matching Management With Customer Needs., Maureen Bredbenner Rn, Cnor, Toni Holcomb Bsn, Rn, Cnor, Louann Newman Rn, Cnor

Patient Care Services / Nursing

No abstract provided.

Decreased Expression Of Atp6v1h In Type 2 Diabetes: A Pilot Report On The Diabetes Risk Study In Mexican Americans, Melanie F. Molina, Hui-Qi Qu, Anne R. Rentfro, Saraswathy Nair, Yang Lu, Craig Hanis, Joseph B. Mccormick, Susan P. Fisher-Hoch

Health & Biomedical Sciences Faculty Publications

Objective: Previous studies in mice and humans observed down-regulation of the gene expression of ATP6V1H associated with type 2 diabetes. This study identified prospectively changes in ATP6V1H expression before and after overt diabetes.

Methods: Expression of ATP6V1H in peripheral blood was compared pre and post development of diabetes in nine individuals.

Results: Considerable variation of ATP6V1H mRNA levels was observed between different individuals. However, within each individual the decrease in expression of ATP6V1H with the development of diabetes was highly statistically significant.

Conclusions: ATP6V1H may represent a critical molecular mechanism involved in the development of type 2 diabetes and its …

Lsuhsc Facilities Biweekly Update: September 2011, Lsuhsc Property And Facilities Management

LSUHSC Facilities Biweekly Updates: 2011

LSUHSC Facilities Biweekly Updates from September 9 and 23, 2011.

These updates describe damage and a timeline of repairs at the LSU Health Sciences Center - New Orleans campus due to Hurricane Katrina which made landfall August 29, 2005.

Lsuhsc Facilities Daily Updates: September 2011, Lsuhsc Property And Facilities Management

LSUHSC Facilities Daily Updates: 2011

LSUHSC Facilities Daily Updates from September 2011.

These updates describe damage and a timeline of repairs at the LSU Health Sciences Center - New Orleans campus due to Hurricane Katrina which made landfall August 29, 2005.

Autoimmune Responses To Atherosclerotic Lipids: A Study In Murine Models Of Atherosclerosis And Obesity, Hanjing Wu

Dissertations and Theses (Open Access)

Atherosclerosis is a chronic, complex arterial disease characterized by intimal lipid accumulation and inflammation. A unique lipid-binding molecule, namely cluster of differentiation 1d (CD1d), may impact atherosclerosis. Structurally, CD1d acts as a nonpolymorphic cell-surface receptor, resembling the major histocompatibility complex-I (MHC-I). While MHC-I restricts peptide antigen presentation to T cells, CD1d presents lipid antigens to T cells named CD1d-restrictedd T cells. Although increased expression of CD1d has been found in human plaques, the exact nature of CD1d-recognized lipids in atherosclerosis remains to be determined. Three groups of lipids may undergo oxidation in atherosclerosis producing atherogenic lipids: phospholipids, fatty acids, and …

Step-Wise Loss Of Bacterial Flagellar Torsion Confers Progressive Phagocytic Evasion, Rustin R. Lovewell, Ryan M. Collins, Julie L. Acker, George A. O'Toole, Matthew J. Wargo, Brent Berwin, Craig R. Roy

Dartmouth Scholarship

Phagocytosis of bacteria by innate immune cells is a primary method of bacterial clearance during infection. However, the mechanisms by which the host cell recognizes bacteria and consequentially initiates phagocytosis are largely unclear. Previous studies of the bacterium Pseudomonas aeruginosa have indicated that bacterial flagella and flagellar motility play an important role in colonization of the host and, importantly, that loss of flagellar motility enables phagocytic evasion. Here we use molecular, cellular, and genetic methods to provide the first formal evidence that phagocytic cells recognize bacterial motility rather than flagella and initiate phagocytosis in response to this motility. We demonstrate …

Chapter: The Advanced Practice Nurse In The Community, Kellie Smith, Molly A. Rose

College of Nursing Faculty Papers & Presentations

Objectives

After reading this chapter, the student should be able to do the following:

1. Briefly discuss the historical development of the roles of the advanced public health nurse and the nurse practitioner

2. Describe the educational requirements for population-focused advanced practice nurses

3. Discuss credentialing mechanisms in nursing as they relate to the role of the advanced practice nurse

4. Compare and contrast the various role functions of population-focused advanced practice nurses

5. Identify potential arenas of practice

6. Explore current issues and concerns related to practice

7. Identify five stressors that may affect nurses in expanded roles

The Role Of Computed Tomography For Identifying Mechanical Bowel Obstruction In A Pakistani Population, Omair Shakil, Syed Nabeel Zafar, Ziaur Rehman, Sarah Saleem, Rehmatullah Khan, Khawaja Muhammad Inam Pal

Section of General Surgery

Objective: To retrospectively review our experience of CT scan in cases with a final diagnosis of surgically confirmed mechanical bowel obstruction.
Methods: It is a retrospective analytical study, done from 2003 to 2008. All adult patients having undergone laparotomy in addition to a preoperative abdominal CT scan over a 5 year period were identified through the medical records and their case notes reviewed. Taking surgery to be the gold standard for diagnosing mechanical bowel obstruction, we compared results of the CT with operative findings to determine the sensitivity, specificity, positive and negative predictive values of CT scans. The data was …

Identifying And Co-Managing The Hiv-Infected Adult: A Guidebook For Primary Care Clinicians, Jason Leider, Susan F. Lelacheur, Julie G. Stewart Dnp, Mph

Nursing Faculty Publications

This guidebook was designed to help primary care clinicians improve their performance in terms of HIV identification and co-management. Surmounting barriers to opt-out screening, making an HIV diagnosis, and preventing transmission and opportunistic infections will be discussed, as will selection of initial therapy and considerations for patients receiving antiretroviral therapy (ART).

Phase Iii Study Of Doxorubicin/Cyclophosphamide With Concomitant Versus Sequential Docetaxel As Adjuvant Treatment In Patients With Human Epidermal Growth Factor Receptor 2–Normal, Node-Positive Breast Cancer: Bcirg-005 Trial, Wolfgang Eiermann, Tadeusz Pienkowski, John Crown, Saeed Sadeghi, Miguel Martin, Arlene Chan, Mansoor Saleh, Sandeep Sehdev, Louise Provencher, Vladimir Semiglazov

Haematology and Oncology, East Africa

Purpose: Anthracyclines, taxanes, and alkylating agents are among the most active agents in treatment of adjuvant breast cancer (BC), but the optimal schedule for their administration is unknown. We performed an adjuvant trial to compare the sequential regimen of doxorubicin with cyclophosphamide (AC) followed by docetaxel (ie, AC>T) with the combination regimen of TAC.

Patients and Methods: Women with node-positive, human epidermal growth factor receptor 2–nonamplified, operable BC were stratified by number of axillary nodes and hormone receptor status and were randomly assigned to adjuvant chemotherapy with six cycles of TAC (75/50/500 mg/m2 every 3 weeks) or four cycles …

World Veterinary Year 2011 250 Years Veterinary Education In The World, Achariya Sailasuta

The Thai Journal of Veterinary Medicine

No abstract provided.

Analysis On Differentially Expressed Genes Of Muscle Tissues In Rugao Chicken At The Ages Of 2 And 12 Weeks By Microarray, Qin De Luan, Guo Bin Chang, Ting Zhen, Zheng Yang Huang, Wei Zhou, Yan Liu, Guo Hong Chen

The Thai Journal of Veterinary Medicine

Microarray containing 13319 probes was used to construct gene expression profiles in order to screendifferentially expressed genes of muscle tissues in Rugao chicken and investigate the molecular mechanism relatedwith muscle tissue traits at 2 and 12 weeks old of chicken. Two hundred and eight differentially expressed genes, ofwhich 108 were known genes, 94 up-regulated, 114 down-regulated were involved in growth, molecular mechanism,fat metabolism, cell proliferation, transcription and splicing factor, protein synthesis and degradation. Meanwhile,some genes of these differentially expressed genes that had no annotation in GenBank were screened out, they werepresumed to be unknown new genes. The differential expressions of …

Effects Of Dietary Protein Deficiency On Plasma Amino Acids And Physical – Histological Conformation Of The Mammary Glands In Lactating Sows, Patrapan Rungcharoen, Sarinee Kalandakanond-Thongsong, Boonrit Thongsong

The Thai Journal of Veterinary Medicine

Eleven multiparous crossbred lactating sows were used to determine the influence of deficient protein dietcontaining 8.2% crude protein and normal protein diet containing 18.2% crude protein on plasma amino acidconcentrations of sows and their piglets, physical mammary gland and histological changes of mammary cells. Theywere provided sufficient water and feed access to one of two isocaloric diets, either deficient (6 sows) or normalprotein diets (5 sows). The experimental period started from farrowing (day 0) until weaning day (day 28). In thisstudy, sows fed deficient protein diet had significant increase in body weight losses and their piglets had significantdecrease in body …

Ultrasound Diagnosis, Phiwipha Kamonrat

The Thai Journal of Veterinary Medicine

No abstract provided.

Antiviral Trims: Friend Or Foe In Autoimmune And Autoinflammatory Disease?, Caroline A. Jefferies, Claire Wynne, Rowan Higgs

Articles

The concept that viral sensing systems, via their ability to drive pro-inflammatory cytokine and interferon production, contribute to the development of autoimmune and autoinflammatory disease is supported by a wide range of clinical and experimental observations. Recently, the tripartite motif-containing proteins (TRIMs) have emerged as having key roles in antiviral immunity — either as viral restriction factors or as regulators of pathways downstream of viral RNA and DNA sensors, and the inflammasome. Given their involvement in these pathways, we propose that TRIM proteins contribute to the development and pathology of autoimmune and autoinflammatory conditions, thus making them potential novel targets …

Isolated Cryptococcal Osteomyelitis In An Immunocompetent Patient, Irfan Qadir, Farheen Ali, Umair Zafar Malik, Masood Umer

Department of Surgery Docs

bstract

Cryptococcosis is a rare infection in HIV-negative individuals. While the lungs and the central nervous system are most commonly infected, skeletal cryptococcosis is uncommon and isolated osteomyelitis due to Cryptococcus neoformans is quite rare. To our knowledge, only 47 cases of isolated cryptococcal osteomyelitis have been reported from 1974 to 2005. We report a case of isolatedcryptococcal osteomyelitis in an immunocompetent patient, who received 12 weeks of fluconazole with complete recovery.

Mucoepidermoid Carcinoma Of The Base Of Tongue, Zain-Ul-Abedeen Sobani, Montasir Junaid, Shehzad Ghaffar, Anwar Suhail

Section of Otolaryngology, Head & Neck Surgery

Mucoepidermoid carcinomas are thought to arise from the reserve cells of salivary gland ducts. Minor salivary glands are located all around the oral cavity and base of the tongue; however few cases of MEC of the base of the tongue have been reported in literature and no guidelines are available for its management. Here we would like to present the case of a 71 year old male with mucoepidermoid carcinoma of the base of the tongue successfully treated with surgical excision and neck dissection. Regular clinical follow up showed no signs of recurrence at 9 months post excision.

Observation Of Ruminococcus Strains In Captive Asian Elephant (Elephas Maximus), Nattawooti Sthitmatee, Pranisa Mahatnirunkul, Patcharaporn Keawmong, Anucha Sirimalaisuwan, Pinich Boontong, Suvichai Rojanasthien, Sumalee Boonmar

The Thai Journal of Veterinary Medicine

Asian elephant is indigenous to many countries including Thailand, but fermenter microorganisms ingastrointestinal tract of the elephant have not fully been investigated. Therefore, this study aimed to observe thecellulolytic bacteria in Genus Ruminococcus in large intestines of captive Asian elephants (Elephas maximus). Fecalsamples were collected from male and female sucklings, young and adult captive Asian elephants. Forty-fourelephants were divided into 3 groups as followed: A) > 18 years old (n=24); B) 2-18 years old (n=17) and C) < 2 yearsold (n=3). The results revealed that there were 214 (42.8%) isolates of R. flavefaciens, 105 (21.0%) isolates of R. bromii, 90(18.0%) isolates of R. obeum, 54 (10.8%) isolates of R. callidus and 37 (7.4%) isolates of R. albus from all fecal samplesexamined. Interestingly, Ruminococcus strains could be isolated from the weaned elephants, but were not found in thesucklings (p<0.05). In conclusion, cellulolytic bacteria in Genus Ruminococcus were isolated from the large intestines ofcaptive Asian elephants. Moreover, the highest prevalence of the bacteria was found in the elephants aged more than18 years old.

The Effect Of Using Long Term And Short Term Extenders During Cooling Process On The Quality Of Frozen Boar Semen, Kampon Kaeoket, Primsiri Chanapai, Puriwat Junchiyaphoom, Panida Chanapiwat

The Thai Journal of Veterinary Medicine

Cooling process of cryopreservation is one of the important factors that affect the qualities of frozen-thawedboar semen. The objective of this study was to compare the qualities of frozen-thawed boar semen after usingdifferent extenders (i.e. BTS, Vitasem LD, ModenaTM and Androstar® plus) during cooling process. Eight sperm-richfractions from 8 boars were employed. The ejaculated semen sample from each boar was divided into four groupsand extended in different freezing extender I as follows: group I (control, short term, BTS), group II (long term,Vitasem LD), group III (long term, ModenaTM) and group IV (long term, Androstar® plus) and kept at 15oC for …

Effect Of Water Temperature On Susceptibility To Streptococcus Agalactiae Serotype Ia Infection In Nile Tilapia (Oreochromis Niloticus), Channarong Rodkhum, Pattanapon Kayansamruaj, Nopadon Pirarat

The Thai Journal of Veterinary Medicine

Streptococcus agalactiae is one of the causative agents associated with warm-water streptococcosis, in whichproduce massive mortality in aquaculture. Emergence of disease in tilapia farm usually occurs in high temperatureseason, which suggested for higher susceptibility of tilapia in this particular condition. Thus, the objective of thisstudy is to investigate the association between water temperature and susceptibility of Nile tilapia (Oreochromisniloticus) to S. agalactiae serotype Ia infection. Nile tilapia were inoculated with 108, 107 or 106 CFU/ml of S. agalactiaeserotype Ia field strain via water immersion route and maintained in different water temperature at 25, 30 or 33oC for1 week. Diseased fish …

Prevalence And Genotype Of Salmonella Choleraesuis In Gunma Prefecture, Japan, Chieko Sakano, Yukio Morita, Koichi Goto, Yoko Yokota, Hideyuki Annaka, Masahiro Fujita, Satoshi Kobatake, Taisei Ishioka, Toshie Hoshino, Sumalee Boonmar, Chaiwat Pulsrikarn, Atsuyoshi Nishina, Kunihisa Kozawa, Shigeki Yamamoto, Hirokazu Kimura

The Thai Journal of Veterinary Medicine

We studied the prevalence of swine salmonellosis and PFGE genotype of isolates in Gunma Prefecture,Japan. Between 2005 and 2008, swine salmonellosis was confirmed in 430 of 2,707,402 (0.02%) swine atslaughterhouses. All isolates were identified as deriving from Salmonella Choleraesuis, biotype Choleraesuis (negativefor H2S production). We used 30 bacterial strains from 15 farms that had experienced outbreaks in 2006 and 2007. Allstrains were susceptible to various antibiotics such as cephems (cefotaxime), fluoroquinolones (norfloxacin andciprofloxacin), and fosfomycin. On the other hand, all strains were resistant to tetracycline (TC), and 29 of 30 (97%)strains were resistant to streptomycin (SM). The most predominant profiles …

Effect Of Roselle (Hibiscus Sabdariffa Linn.) Calyx In Laying Hen Diet On Egg Production Performance, Egg Quality And Tbars Value In Plasma And Yolk, Piyaphon Sukkhavanit, Kris Angkanaporn, Suwanna Kijparkorn

The Thai Journal of Veterinary Medicine

An experiment was conducted to investigate the effect of Roselle calyx in two preparation forms in layerdiets on egg production performance, egg quality and TBARS value in plasma and yolk. Two hundred and seventy,33-week-old, CP Brown laying hens were randomly allocated into 6 treatments with 5 replications of 9 hens each.The dietary treatments were control diet, control diet supplemented with 250 mg/kg α-tocopheryl acetate, dietcontaining 1 and 2% of Roselle calyx crude extracts, and diet containing 2% and 4% Roselle calyx powder. Eggproduction performance was recorded, egg quality was measured and TBARS value in plasma and yolk wereanalyzed after fed …

Detection Of West Nile Virus In Mosquitoes In Nakhon-Pathom And Phetchaburi Province, Thailand, Kriangkrai Witoonsatian, Nuananong Sinwat, Rungroj Jam-On, Khongsak Thiangtum, Thaweesak Songserm

The Thai Journal of Veterinary Medicine

West Nile (WN) disease is one of the encephalitic diseases in humans and mammals. This disease has beenreported in several areas of the world. Thailand is located in the area of high risk of WN virus (WNv) infectionconcerning a natural transmission cycle. However, the WNv infection has not been previously reported. Therefore,the aim of this study was to detect WNv in mosquitoes in some areas in Nakhon-pathom and Phetchaburi provinces,central Thailand. The period of this study was done during November 2008 to November 2010. We found that therewere four genera collected including Aedes, Anopheles, Culex and Mansonia. Culex spp such …

45 25 Gram Versus 50 Gram Of 25% Albumin In Preventing Renal Impairment After Large Volume Paracentesis In Cirrhosis.Khali, A. B. Khalid, Mumtaz J Khan, A Ghufran, Syed H Shah, Saeed Hamid, Wasim Jafri

Section of Gastroenterology

No abstract provided.