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2010

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Articles 4531 - 4560 of 5702

Full-Text Articles in Medicine and Health Sciences

Oxidative Predictors And Lipoproteins In Male Soccer Players, Faruk Yamaner Jan 2010

Oxidative Predictors And Lipoproteins In Male Soccer Players, Faruk Yamaner

Turkish Journal of Medical Sciences

To determine male soccer players’ lipoprotein levels, and their total antioxidant capacity, total oxidant status, oxidative stress index, and lipid hydroperoxide and lipoprotein levels after exercise. Materials and methods: The study group included 33 certificated male soccer players with an age range of 17-20 years and the control group included 53 healthy male volunteers with an age range of 18-20 years. Their total antioxidant capacity, total oxidant status, oxidative stress index, and lipid hydroperoxide and lipoprotein levels were analyzed and compared. Results: In the baseline, plasma levels, total oxidant statuses, oxidative stress indices, and lipid hydroperoxide levels were found of …

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Molecular Analyses Of Salmonella Serotype Typhi And Salmonella Serotype Paratyphi B Strains Isolated In Turkey, Istar Dolapçi, Bi̇rsel Erdem, Alper Tekeli̇, Ebru Us, Mehseti̇ Bayramova, Begüm Saran, Fi̇kret Şahi̇n Jan 2010

Molecular Analyses Of Salmonella Serotype Typhi And Salmonella Serotype Paratyphi B Strains Isolated In Turkey, Istar Dolapçi, Bi̇rsel Erdem, Alper Tekeli̇, Ebru Us, Mehseti̇ Bayramova, Begüm Saran, Fi̇kret Şahi̇n

Turkish Journal of Medical Sciences

To investigate the characteristics of Salmonella serotype Typhi and Salmonella serotype Paratyphi B, which still remain significant in Turkey. Materials and methods: Eighteen S. Typhi and 42 S. Paratyphi B strains isolated from clinical samples were investigated by plasmid profile analysis, enterobacterial repetitive intergenic consensus-polymerase chain reaction (ERIC-PCR), and pulsed field gel electrophoresis (PFGE) methods. Results: Plasmid profile analysis showed that 10 out of 18 (56%) S. Typhi isolates harbored 1 to 3 plasmids, and 11 out of 42 (26.2%) S. Paratyphi B isolates harbored 1 to 4 plasmids. PFGE performed with restriction enzyme AvrII grouped both S. Typhi and …

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Are Serum Aluminum Levels A Risk Factor In The Appearance Of Spontaneous Pneumothorax?, Serdar Han, Rasi̇h Yazkan, Bülent Koçer, Gülteki̇n Gülbahar, Serdal Kenan Köse, Koray Dural, Ünal Sakinci Jan 2010

Are Serum Aluminum Levels A Risk Factor In The Appearance Of Spontaneous Pneumothorax?, Serdar Han, Rasi̇h Yazkan, Bülent Koçer, Gülteki̇n Gülbahar, Serdal Kenan Köse, Koray Dural, Ünal Sakinci

Turkish Journal of Medical Sciences

To investigate the relationship between aluminum and spontaneous pneumothorax (SP) development. Materials and methods: A patient group and a control group were formed with 100 individuals in each. The serum aluminum levels of the groups were determined and statistically compared. Results: The mean serum aluminum levels were 5.6 ± 2.4 \mug/L (1.6-11.9) and 23.2 ± 15.4 \mug/L (2-81) in the control and SP groups, respectively (P < 0.001). The specificity and sensitivity of the measurement of aluminum level were 74.4% and 86.4% in the SP group. The risk of SP development was found to be 18 times higher in individuals with high serum levels of aluminum compared to that in individuals with low serum levels of aluminum. Conclusion: A high level of aluminum is a risk factor for the development of SP.

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Does Melatonin Alleviate Cold Preservation Injury Of The Liver?, Ömer Günal, Abdurrahman Coşkun, Ari̇f Aslaner, Ümran Yildirim Jan 2010

Does Melatonin Alleviate Cold Preservation Injury Of The Liver?, Ömer Günal, Abdurrahman Coşkun, Ari̇f Aslaner, Ümran Yildirim

Turkish Journal of Medical Sciences

To investigate the effect of melatonin added to preservation solution on liver cold ischemia. Materials and methods: Twenty male Wistar albino rats were divided equally into groups treated with University of Wisconsin (UW) solution with and without melatonin. The LDH, AST, and ACP activities of the preservation solutions were determined in samples collected at 2, 24, 36, and 48 h. Tissue malondialdehyde and heat shock protein (HSP 70) levels were also measured and a histological examination was performed at 48 h. Results: Melatonin prevented enzyme elevation, induced heat shock protein (HSP 70), and decreased lipid peroxidation effectively in comparison to …

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Serum Leptin, Lipoprotein Levels, And Glucose Homeostasis Between National Wrestlers And Sedentary Males, Faruk Yamaner, Taner Bayraktaroğlu, Hulusi̇ Atmaca, Mehmet Aki̇f Zi̇yagi̇l, Kemal Tamer Jan 2010

Serum Leptin, Lipoprotein Levels, And Glucose Homeostasis Between National Wrestlers And Sedentary Males, Faruk Yamaner, Taner Bayraktaroğlu, Hulusi̇ Atmaca, Mehmet Aki̇f Zi̇yagi̇l, Kemal Tamer

Turkish Journal of Medical Sciences

Leptin is an important controller of the size of fat stores by inhibiting appetite. In wrestling, fat metabolism is important not only for aerobic energy system, but also for weight control and weight loss before competition. The aim of this study was to measure and compare the serum leptin levels, glucose homeostasis, and serum lipoproteins between Turkish national wrestlers and sedentary males. Materials and methods: Forty-five Turkish national wrestlers at the end of Olympic training camp before Beijing 2008 Olympic Games and 43 sedentary students were selected as subjects. Post-exercise levels of serum leptin, HOMA (Homeostasis model assessment) values, triglycerides, …

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Investigation Of Enos Gene Intron 4 A/B Vntr And Intron 23 Polymorphisms In Patients With Essential Hypertension, İdri̇s Mehmetoğlu, Gülsüm Yilmaz, Sevi̇l Kurban, Hasan Acar, M. Aki̇f Düzenli̇ Jan 2010

Investigation Of Enos Gene Intron 4 A/B Vntr And Intron 23 Polymorphisms In Patients With Essential Hypertension, İdri̇s Mehmetoğlu, Gülsüm Yilmaz, Sevi̇l Kurban, Hasan Acar, M. Aki̇f Düzenli̇

Turkish Journal of Medical Sciences

Nitric oxide (NO) plays a major role in the regulation of vascular tone. Production of NO can be influenced by polymorphisms of the endothelial NO synthase (eNOS) gene, which may be associated with the pathogenesis of essential hypertension (EHT). Therefore, eNOS gene intron 4 a/b variable number of tandem repeats (VNTR) and intron 23 polymorphisms were investigated in patients with EHT living in a central area of Turkey. Materials and methods: The study was performed in 91 patients (34 M, 57 F) with EHT, aged 38-76 years, and 75 age- and sex-matched healthy controls (35 M, 40 F). eNOS gene …

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Genotyping Of Trichosporon Asahii Strains Isolated From Urinary Tract Infections In A Turkish University Hospital, Zeynep Ceren Karahan, Esra Koyuncu, Istar Dolapçi, Özay Arikan Akan, Füsun Can, Alper Tekeli̇ Jan 2010

Genotyping Of Trichosporon Asahii Strains Isolated From Urinary Tract Infections In A Turkish University Hospital, Zeynep Ceren Karahan, Esra Koyuncu, Istar Dolapçi, Özay Arikan Akan, Füsun Can, Alper Tekeli̇

Turkish Journal of Medical Sciences

Trichosporon infections are associated with a wide spectrum of clinical manifestations. Trichosporon asahii is the most important species in the genus. Our aim was to evaluate the genotypic relatedness of urinary T. asahii strains isolated from immunocompetent patients during a hospital outbreak. Materials and methods: Twenty-three T. asahii isolates obtained from 15 patients hospitalized in different wards of Ankara University Ibn-i Sina Hospital between July 2004 and April 2005 were studied. T. asahii was identified by API 20C AUX (BioMérieux Vitek, Hazelwood, USA) system and confirmed by genus and species specific polymerase chain reactions. Genetic relatedness of the isolates was …

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Transthoracic Lung And Mediastinal Biopsies Obtained With The Tru-Cut Technique: 10 Years’ Experience, Şeri̇fe Savaş Bozbaş, Şule Akçay, Fi̇gen Öztürk Ergür, Cüneyt Ayteki̇n Jan 2010

Transthoracic Lung And Mediastinal Biopsies Obtained With The Tru-Cut Technique: 10 Years’ Experience, Şeri̇fe Savaş Bozbaş, Şule Akçay, Fi̇gen Öztürk Ergür, Cüneyt Ayteki̇n

Turkish Journal of Medical Sciences

Percutaneous needle biopsy has been used successfully in many organ systems with excellent results and few complications. In this study, we sought to evaluate percutaneous transthoracic biopsy results using a coaxial system. Materials and methods: The records of 302 patients (mean age, 63.1 years) who underwent percutaneous CT-guided coaxial cutting needle lung and mediastinal biopsy were retrospectively evaluated. Number, diameter, location of the lesions, calcification, and emphysema on lung parenchyma were noted. The number of specimens obtained, complications after the procedure, and treatment of complications were recorded. Results: From lesions identified in 270 patients on thoracic CT, a mean of …

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A Novel Hand-Held Device For The Measurement Of Ocular Alignment, Uğur E. Altiparmak, Esra Karabulut, Eric R. Eggenberger Jan 2010

A Novel Hand-Held Device For The Measurement Of Ocular Alignment, Uğur E. Altiparmak, Esra Karabulut, Eric R. Eggenberger

Turkish Journal of Medical Sciences

The measurement of ocular alignment can be challenging and difficult to reproduce. A method for the measurement of ocular alignment with accuracy, speed, and reproducibility would be a useful clinical addition. Materials and methods: A hand-held device consisting of a rotary prism and a red Maddox rod was constructed. This was used to evaluate 18 patients with ocular misalignment and the results were compared with the ones obtained using the prism cover testing. Results: The results from the hand-held device showed a close correlation with those of the prism cover test. Conclusion: The hand-held instrument is a useful method to …

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Effects Of Grape Consumption On Plasma And Erythrocyte Antioxidant Parameters In Elderly Subjects, Aslihan Avci, Tesli̇me Atli, İmge B. Ergüder, Murat Varli, Erdi̇nç Devri̇m, Özgür Demi̇r, İlker Durak, Murat Turgay Jan 2010

Effects Of Grape Consumption On Plasma And Erythrocyte Antioxidant Parameters In Elderly Subjects, Aslihan Avci, Tesli̇me Atli, İmge B. Ergüder, Murat Varli, Erdi̇nç Devri̇m, Özgür Demi̇r, İlker Durak, Murat Turgay

Turkish Journal of Medical Sciences

To investigate the effects of ingesting Fructus vitis minuta (black grape) on plasma and erythrocyte antioxidant parameters in elderly subjects. Materials and methods: Thirteen subjects (mean age 74.67 ± 0.58) participated in the study. They consumed 1 g/kg body weight per day of dried black Maraş grapes for 1 month. Before and after these periods, fasting blood samples were obtained, and oxidant (as MDA) and antioxidant (as SOD) parameters were studied in erythrocytes. Also, plasma samples were obtained from the subjects. Results: In the erythrocyte hemolysate, MDA (malondialdehydes) levels and SOD (superoxide dismutase) activities were found to be lower (P < 0.01) in the second samples compared to the first ones. Conclusion: We think that because free radical production was decreased SOD activities were not increased. Our results show that reduced peroxidation processes caused by Maraş grape consumption suggest that grape consumption has beneficial effects in elderly subjects.

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Effect Of Essential Hypertension On Qtc Dispersion In Patients With Intracerebral Haemorrhage, Dursun Aygün, Bülent Şi̇şman, Mehmet Seli̇m Nural, Özcan Yilmaz, Ahmet Baydin Jan 2010

Effect Of Essential Hypertension On Qtc Dispersion In Patients With Intracerebral Haemorrhage, Dursun Aygün, Bülent Şi̇şman, Mehmet Seli̇m Nural, Özcan Yilmaz, Ahmet Baydin

Turkish Journal of Medical Sciences

To investigate the effects of essential hypertension on QTc dispersion (QTcd) in patients with intracerebral haematoma (ICH). Materials and methods: This prospective study included adult patients presenting with acute ICH within the first 24 h of ictus to the Emergency Department (ED). On admission, following the first clinical assessment of patients, a complete 12-lead ECG and non-contrast computed tomography (CT) were obtained from each patient. Then, the patients were divided into 2 subgroups according to the presence of hypertension history. The patient groups were compared to each other as well as the control group for QTcd. Results: The study groups …

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Investigation Of Premenstrual Syndrome And Contributing Factors Among University Students*, Nülüfer Erbi̇l, Ayşenur Karaca, Tülay Kiriş Jan 2010

Investigation Of Premenstrual Syndrome And Contributing Factors Among University Students*, Nülüfer Erbi̇l, Ayşenur Karaca, Tülay Kiriş

Turkish Journal of Medical Sciences

To determine the frequency of premenstrual syndrome (PMS) and to investigate contributing factors for PMS among female students in a university dormitory in Ordu. Materials and methods: This descriptive study was conducted with female students at a public university dormitory in Ordu, in the East Black Sea region of Turkey. The sample contained 300 female students at the university dormitory. The study was conducted between 3 January and 12 January 2007. The research data were collected via a 22-item socio-demographic information questionnaire and the Premenstrual Syndrome Scale (PMSS) developed by Gençdoğan. Results: It was determined that the participants' mean age …

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The Effect Of Microorganisms On Cytokine Secretion From Bone Marrow Dendritic Cells, Işil Fi̇dan, Ayşe Kalkanci, Emi̇ne Yeşi̇lyurt, Berna Erdal, Semra Kuşti̇mur, Turgut İmi̇r Jan 2010

The Effect Of Microorganisms On Cytokine Secretion From Bone Marrow Dendritic Cells, Işil Fi̇dan, Ayşe Kalkanci, Emi̇ne Yeşi̇lyurt, Berna Erdal, Semra Kuşti̇mur, Turgut İmi̇r

Turkish Journal of Medical Sciences

Dendritic cells (DCs) are potent antigen-presenting cells crucial for initiation of cell-mediated immune responses to foreign antigens. They also contribute to the innate resistance against microbial pathogens. The present study examined the effect of microorganisms such as Escherichia coli (E. coli), Serratia marcescens (S. marcescens), Methicillin-resistant Staphylococcus aureus (MRSA), coagulase negative staphylococci (CoNS), and Candida albicans (C. albicans) on cytokine secretion in bone marrow-dendritic cells (BM-DCs). Materials and methods: The levels of cytokines in culture supernatants of the BM-DC were determined by enzyme-linked immunosorbent assay. Results: DCs stimulated by microorganisms produced large amounts of TNF-\alpha, IL-1\beta, IL-6, and IL-10. The …

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Underestimated Role Of Alcohol At Skin Disinfection: Lipid Dissolving Property When Used In Association With Conventional Antiseptic Agents, Alp Yentür, İsmet Topçu, Ruşen Işik, Kenan Değerli̇, Süheyla Sürücüoğlu Jan 2010

Underestimated Role Of Alcohol At Skin Disinfection: Lipid Dissolving Property When Used In Association With Conventional Antiseptic Agents, Alp Yentür, İsmet Topçu, Ruşen Işik, Kenan Değerli̇, Süheyla Sürücüoğlu

Turkish Journal of Medical Sciences

After conventional aqueous disinfectant solutions, it was shown that microorganisms were still protected in hair follicles. We hypothesized that those aqueous disinfectant solutions when used in combination with alcohol may be more effective on the inhibition of recolonization of skin and therefore catheter tip colonization. Materials and methods: Skin surface samples were taken from epidural catheter insertion sites prior to catheterization, and before and after disinfection with different combinations of povidone-iodine, chlorhexidine, and alcohol. Before catheter removal, cultures were taken once more and tips of the catheters were cultured. Results: Catheter tip colonization and skin culture results of 10% povidone-iodine …

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Comparative Efficacy Of Caffeic Acid Phenethyl Ester (Cape), Olopatadine Hydrochloride, And Dexamethasone Sodium Phosphate In Experimental Allergic Conjunctivitis*, Erdi̇nç Aydin, Heli̇n Deni̇z Demi̇r, Hüseyi̇n Özyurt, Ünal Erkorkmaz Jan 2010

Comparative Efficacy Of Caffeic Acid Phenethyl Ester (Cape), Olopatadine Hydrochloride, And Dexamethasone Sodium Phosphate In Experimental Allergic Conjunctivitis*, Erdi̇nç Aydin, Heli̇n Deni̇z Demi̇r, Hüseyi̇n Özyurt, Ünal Erkorkmaz

Turkish Journal of Medical Sciences

To compare the antiallergic efficacy of 1% caffeic acid phenethyl ester (CAPE), 0.1% olopatadine hydrochloride, and 0.1% dexamethasone sodium phosphate. Materials and methods: Experimental allergic conjunctivitis was provoked by a mast cell activator (compound 48/80) in 31 New Zealand rabbits. The rabbits were divided into 3 groups, and 1% CAPE, 0.1% olopatadine hydrochloride, and 0.1% dexamethasone sodium phosphate were instilled 30 min before and 15 min after the provocation. The edema and hyperemia in the experimental (right) eyes and control (left) eyes were scored in each group. Anterior segment photographs and conjunctival samples for histopathological evaluation and scoring were taken. …

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Histopathological Effects Of Chronic Fluorosis On The Liver Of Mice (Swiss Albino), Yusuf Ersan, Evren Koç, İsmai̇l Ari, Başaran Karademi̇r Jan 2010

Histopathological Effects Of Chronic Fluorosis On The Liver Of Mice (Swiss Albino), Yusuf Ersan, Evren Koç, İsmai̇l Ari, Başaran Karademi̇r

Turkish Journal of Medical Sciences

Fluoride intake in high doses has toxic effects on various organs. Chronic fluorosis results in tubular degenerations, inflammation, fibrosis, parenchymatous nephritis, cloudy swellings, and dilations of convoluted tubules. In addition to these effects, fluoride causes deteriorative effects on the skeleton, teeth, and soft tissues. The goal of this study was to examine the impacts of chronic fluorosis on the liver tissues of mice. Materials and methods: One control group and 3 experimental groups, each group consisting of 4 male and 4 female mice, were formed to conduct the experiment. A stock solution including 2000 ppm fluoride was prepared by solving …

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Effects Of Alendronate And Risedronate Therapy On Hepatic Antioxidant Enzyme Activity And Lipid Peroxidation In Ovariectomized Rats, Serap Yalin, Ülkü Çömelekoğlu, Selda Bağiş, Mehmet Berköz, Peli̇n Eroğlu Jan 2010

Effects Of Alendronate And Risedronate Therapy On Hepatic Antioxidant Enzyme Activity And Lipid Peroxidation In Ovariectomized Rats, Serap Yalin, Ülkü Çömelekoğlu, Selda Bağiş, Mehmet Berköz, Peli̇n Eroğlu

Turkish Journal of Medical Sciences

To evaluate the effects of alendronate (ALN) and risedronate (RIS), which are agents for preventing and treating postmenopausal osteoporosis, on hepatic antioxidant enzyme activity and lipid peroxidation in ovariectomized rats. Materials and methods: Thirty-two female rats were randomly assigned to 4 separate groups. All of the groups, except the control group, were ovariectomized. Included in the 4 groups were a control group (C), an ovariectomized group (OVX), an ovariectomized group treated with alendronate (OVX-ALN), and an ovariectomized group treated with risedronate (OVX-RIS). Ten weeks after an ovariectomy, the OVX-ALN rats were administered 1.75 mg/kg of their body weight with alendronate …

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N-Acetyltransferase 2 Gene Polymorphisms And Susceptibility To Prostate Cancer: A Pilot Study In The Turkish Population, Buket Kosova, Vi̇ldan Bozok Çeti̇ntaş, Ahmet Çağ Çal, Asli Teti̇k, Ruki̇ye Özel, Çağdaş Aktan, Cumhur Gündüz, Nejat Topçuoğlu, İbrahi̇m Kadri̇ Cürekli̇batir, Fatma Zuhal Eroğlu Jan 2010

N-Acetyltransferase 2 Gene Polymorphisms And Susceptibility To Prostate Cancer: A Pilot Study In The Turkish Population, Buket Kosova, Vi̇ldan Bozok Çeti̇ntaş, Ahmet Çağ Çal, Asli Teti̇k, Ruki̇ye Özel, Çağdaş Aktan, Cumhur Gündüz, Nejat Topçuoğlu, İbrahi̇m Kadri̇ Cürekli̇batir, Fatma Zuhal Eroğlu

Turkish Journal of Medical Sciences

To investigate the association between the 3 most frequently observed single nucleotide polymorphisms of the NAT2 gene and the risk of developing prostate cancer in the Turkish population. Materials and methods: A total of 110 unrelated patients with prostate cancer were included in this case-control association study and constituted the study group. The control group also consisted of 150 unrelated but healthy men. Genomic DNA was isolated from peripheral blood leukocytes of all patients and analyzed with a sensitive real-time PCR method. After melting curve analysis genotypes were identified for the NAT2*5A, NAT2*6A, and NAT2*7A/B polymorphisms. Results: Prostate cancer patients …

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Absence Of Vancomycin-Resistant Enterococci (Vre) Despite The Presence Of Risk Factors: A Survey Of Rectal Carriage Of Vre*, Zeli̇ha Koçak Tufan, Selcan Arslan, Sali̇h Cesur, Cemal Bulut, Hasan Irmak, Sami̇ Kinikli, Ferah Ergi̇n, Ali̇ Kutta Çeli̇k, Ali̇ Pekcan Demi̇röz Jan 2010

Absence Of Vancomycin-Resistant Enterococci (Vre) Despite The Presence Of Risk Factors: A Survey Of Rectal Carriage Of Vre*, Zeli̇ha Koçak Tufan, Selcan Arslan, Sali̇h Cesur, Cemal Bulut, Hasan Irmak, Sami̇ Kinikli, Ferah Ergi̇n, Ali̇ Kutta Çeli̇k, Ali̇ Pekcan Demi̇röz

Turkish Journal of Medical Sciences

The resistant organisms from patients and healthcare workers (HCWs) first colonized the gastrointestinal tract before causing infections in patients. In this study, presence of risk factors for vancomycin-resistant enterococci (VRE) colonization and the prevalence of rectal carriage of VRE among HCWs and hospitalized patients in the absence of an outbreak were investigated. Design: Cross-sectional study. Setting: A 600-bed training and research hospital. Materials and methods: A total of 508 intensive-care unit (ICU) patients and HCWs in these units were included. Risk factors such as previous antibiotic use, especially vancomycin and cephalosporin, the presence of invasive devices like catheters, and co-morbid …

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Pulmonary Hydatid Disease In Southeastern Anatolia, Turkey, Selver Özeki̇nci̇, Şule Bakir, Ali̇ Kemal Uzunlar, Şevval Eren Jan 2010

Pulmonary Hydatid Disease In Southeastern Anatolia, Turkey, Selver Özeki̇nci̇, Şule Bakir, Ali̇ Kemal Uzunlar, Şevval Eren

Turkish Journal of Medical Sciences

To evaluate retrospectively epidemiological parameters and clinicopathologic figures of pulmonary hydatid disease in our region. Materials and methods: A total of 117 cases of human pulmonary hydatid disease were included in this study, and these cases were diagnosed in the Department of Pathology of Dicle University Medical School, between 1987 and 2007. The patients' data were retrospectively collected from archival reports; in addition, some of the patients were still alive and contactable. Results: Our 117 cases consisted of 66 (56.41%) females and 51 (43.58%) males. The average age was 28.18. Pulmonary hydatidosis appears to be more common in younger individuals. …

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Thyroid Hormone Reference Intervals And The Prevalence Of Thyroid Antibodies, Aydan Çelebi̇ler, Si̇bel Bi̇lgi̇li̇, Emi̇ne Ömür Erkizan, Huri̇ye Seri̇n, Muhammet Baysal Karaca Jan 2010

Thyroid Hormone Reference Intervals And The Prevalence Of Thyroid Antibodies, Aydan Çelebi̇ler, Si̇bel Bi̇lgi̇li̇, Emi̇ne Ömür Erkizan, Huri̇ye Seri̇n, Muhammet Baysal Karaca

Turkish Journal of Medical Sciences

To establish new reference intervals for thyrotropin (TSH), free thyroxine (FT4), and free triiodothyronine (FT3) on the Beckman Coulter DxI 800 in healthy Turkish adults and assess the prevalence of laboratory evidence of thyroid antibodies in this population. Materials and methods: Specimens were obtained from 619 healthy volunteers (338 females, 281 males).The study was conducted with health care professionals and their relatives, The mean age of all the subjects was 34.7 and the median was 31 years, with ages ranging from 15 to 84. Moreover, the subjects had no evidence of thyroid autoimmunity or a history of drug use, both …

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Letter To The Editor, Di̇lşen Çolak, Arzu Akşahi̇n, Mustafa Altinbaş Jan 2010

Letter To The Editor, Di̇lşen Çolak, Arzu Akşahi̇n, Mustafa Altinbaş

Turkish Journal of Medical Sciences

No abstract provided.

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Prediction Of Prostate Cancer Using Decision Tree Algorithm, Kemal Hakan Gülkesen, İsmai̇l Türker Köksal, Sebahat Özdem, Osman Saka Jan 2010

Prediction Of Prostate Cancer Using Decision Tree Algorithm, Kemal Hakan Gülkesen, İsmai̇l Türker Köksal, Sebahat Özdem, Osman Saka

Turkish Journal of Medical Sciences

Serum Prostate Specific Antigen (PSA) level is used for prediction of cancer, but this approach suffers from weak sensitivity and specificity. We applied binary-split decision tree (DT) algorithm to prostate cancer prediction problem. Materials and methods: Quick, Unbiased and Efficient Statistical Tree (QUEST) algorithm was used in 750 patients who had a serum PSA levels between 0 and 10 ng/mL. Results: The analysis indicated that following five nodes had different levels of cancer possibility: (1) PSA > 5.98 ng/mL; (2) PSA 0.81; (4) PSA Keywords:

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Serum Adenosine Deaminase Activity And The Total Antioxidant Capacity Of Plasma In Pulmonary Tuberculosis And Non-Tuberculosis Pulmonary Disease, Mohammad Naderi, Mohammad Hashemi, Ali Mehdizadeh, Hamid Mehrabifar, Hamid Reza Kouhpayeh, Hossein Ansari, Gholamreza Bahari, Saeid Ghavami Jan 2010

Serum Adenosine Deaminase Activity And The Total Antioxidant Capacity Of Plasma In Pulmonary Tuberculosis And Non-Tuberculosis Pulmonary Disease, Mohammad Naderi, Mohammad Hashemi, Ali Mehdizadeh, Hamid Mehrabifar, Hamid Reza Kouhpayeh, Hossein Ansari, Gholamreza Bahari, Saeid Ghavami

Turkish Journal of Medical Sciences

The aim of this study was to investigate the level of serum adenosine deaminase (ADA) and the total antioxidant capacity (TAC) in pulmonary tuberculosis (PTB), non-tuberculosis pulmonary disease (non-PTB) and healthy subjects. Materials and methods: Serum ADA activity was measured using the Giusti and Galanti method, and the total antioxidant capacity of plasma was determined by the ferric reducing ability of plasma (FRAP) test. Results: The serum ADA levels were significantly higher (P < 0.001) in pulmonary TB (PTB, 19.78 ± 7.09 U/L), as well as in non-PTB patients (14.78 ± 4.65 U/L) when compared to healthy controls (10.02 ± 1.99 U/L). The sensitivity and specificity were found to be 71.7% and 63.3%, respectively, in distinguishing PTB from non-PTB. In distinguishing PTB from healthy subjects, the sensitivity and specificity were 87% and 93.3%, respectively. The TAC was significantly lower in PTB (485.2 ± 190.0 µM) and non-PTB patients (588.3 ± 195.8 µM), when compared to the controls (784.3 ± 190.0 µM; P < 0.001). Plasma antioxidative activity decreased in PTB and non-PTB patients when compared to the controls. Conclusion: We concluded that serum ADA activity is not a useful test to differentiate pulmonary TB from other respiratory diseases. The TAC is low in pulmonary TB, therefore supplementation with a suitable anti-oxidant may be useful.

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Chronic Pain And Depression: A Descriptive Survey Among Adult Primary Health Care Centre Patients, Nüket Paksoy Erbaydar, Nesri̇n Çi̇li̇ngi̇roğlu Jan 2010

Chronic Pain And Depression: A Descriptive Survey Among Adult Primary Health Care Centre Patients, Nüket Paksoy Erbaydar, Nesri̇n Çi̇li̇ngi̇roğlu

Turkish Journal of Medical Sciences

Knowledge of chronic pain and its relationship to depression among primary health care patients in Turkey is inadequate. The aim of this study was to evaluate the frequency of chronic pain and its relationship to depression. Materials and methods: In this descriptive study, data was collected with a questionnaire based on sociodemographic and pain-related characteristics, which was administered to a study population (n = 259) of primary care patients, 18-64 years old. The Visual Analogue Scale (VAS) (min-max = 0-10) and Beck Depression Inventory (BDI) (min-max = 0-63) were used for the assessment of pain severity and depression. Results: Of …

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Effects Of Vitamin A And C And Melatonin On 3-Nitrotyrosine Formation In Guinea Pig Heart Under Lipopolysaccharide-Induced Stress, Hali̇l Yaman, Tuncer Çayci, Meli̇k Seyrek, Emi̇n Özgür Akgül, Yasemi̇n Gülcan Kurt, İbrahi̇m Aydin, Hakan Yaren, Erdi̇nç Çakir, Ömer Özcan, Behzat Çi̇men, Nurten Türközkan, Mehmet Kemal Erbi̇l Jan 2010

Effects Of Vitamin A And C And Melatonin On 3-Nitrotyrosine Formation In Guinea Pig Heart Under Lipopolysaccharide-Induced Stress, Hali̇l Yaman, Tuncer Çayci, Meli̇k Seyrek, Emi̇n Özgür Akgül, Yasemi̇n Gülcan Kurt, İbrahi̇m Aydin, Hakan Yaren, Erdi̇nç Çakir, Ömer Özcan, Behzat Çi̇men, Nurten Türközkan, Mehmet Kemal Erbi̇l

Turkish Journal of Medical Sciences

Bacterial lipopolysaccharide (LPS) triggers synthesis of nitric oxide (NO) and superoxide (O_2^{.-}). O_2^{.-} can react with NO to produce the powerful oxidant peroxynitrite (ONOO-). The presence of 3-nitrotyrosine (3-NT) in tissues is often used as a marker of ONOO- production. Vitamin A, vitamin C, and melatonin are potent antioxidant molecules. We sought to clarify this issue by examining the effects of vitamin A (15,000 IU/kg/day), vitamin C (600 mg/kg/day), and melatonin (25 mg/kg) on 3-NT formation in heart tissue in a guinea pig model of LPS-induced endotoxemia. Materials and methods: A total of 75 animals were randomly divided into 5 …

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Penile Mondor's Disease Can Be Effectively Treated With The Use Of An Acetyl Salicylic Acid And Pentoxifylline Combination, Mürsel Davarci, Eşref Oğuz Güven, Ahmet Gökçe, Fati̇h Rüştü Yalçinkaya, Ahmet Namik Ki̇per, Mevlana Derya Balbay Jan 2010

Penile Mondor's Disease Can Be Effectively Treated With The Use Of An Acetyl Salicylic Acid And Pentoxifylline Combination, Mürsel Davarci, Eşref Oğuz Güven, Ahmet Gökçe, Fati̇h Rüştü Yalçinkaya, Ahmet Namik Ki̇per, Mevlana Derya Balbay

Turkish Journal of Medical Sciences

Since penile Mondor's disease is a rare condition, different treatment choices are used. Herein we recommend a new treatment strategy with acetylsalicylic acid and pentoxifylline, which was tested in 14 patients with penile Mondor's disease. Materials and methods: Fourteen patients with the clinical presentation of penile Mondor's disease were included. Patients were given acetylsalicylic acid (ASA) 500 mg qid and pentoxifylline 600 mg bid for 14 days. Physical examinations were performed in all patients. In addition, ultrasonic examinations were done before the treatment and on days 7 and 14 of treatment to evaluate dorsal vein thrombosis. Results: Physical examinations revealed …

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Dissection Of Mesoappendix In Laparoscopic Appendectomy: A Comparison Of Monopolar Cautery And Bipolar Vessel Sealing System, Emrah Şenel, Fati̇h Akbiyik, Hali̇l Faruk Atayurt, Hüseyi̇n Tuğrul Ti̇ryaki̇ Jan 2010

Dissection Of Mesoappendix In Laparoscopic Appendectomy: A Comparison Of Monopolar Cautery And Bipolar Vessel Sealing System, Emrah Şenel, Fati̇h Akbiyik, Hali̇l Faruk Atayurt, Hüseyi̇n Tuğrul Ti̇ryaki̇

Turkish Journal of Medical Sciences

Various technique and different instruments like endoscopic stapler, endoscopic clip, monopolar cautery, harmonic scalpel, and bipolar vessel sealer can be used in the dissection of appendix mesentery when performing laparoscopic appendectomy. The aim of this study is to evaluate the effects of using monopolar cautery and bipolar vascular sealing instruments in the dissection of mesentery of appendix on the duration of the operation of pediatric patients. Materials and methods: Sixty three patients, operated laparoscopically for acute appendicitis in between June 2008 and June 2009 at the Pediatric Surgery Clinic of Dışkapı Children's Hospital, are evaluated retrospectively. Monopolar cautery was used …

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Comparative Effects Of Levosimendan And Dobutamine Infusion On P Wave Dispersion In Patients With Acute Decompensated Heart Failure, Ati̇la İyi̇soy, Turgay Çeli̇k, Murat Çeli̇k, Bariş Buğan, Hali̇l Yaman Jan 2010

Comparative Effects Of Levosimendan And Dobutamine Infusion On P Wave Dispersion In Patients With Acute Decompensated Heart Failure, Ati̇la İyi̇soy, Turgay Çeli̇k, Murat Çeli̇k, Bariş Buğan, Hali̇l Yaman

Turkish Journal of Medical Sciences

We aimed to evaluate the comparative effects of levosimendan and dobutamine on P-wave dispersion (PWD) in the patients with acute decompensated heart failure (ADHF). Materials and methods: The study population consisted of 40 patients (mean age = 68 years, 23 men, NYHA class III-IV) presented with ADHF. Patients were randomized to intravenous levosimendan (n = 20) or dobutamine (n = 20) groups. The P-wave duration measurements were calculated in 12-lead surface ECG simultaneously and recorded before and after treatment. Manual measurements of P-wave duration were performed with digital calipers on a high resolution computer screen by two cardiologists not aware …

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Prevalence Of Anaemia In Women Of Reproductive Age In Meghalaya: A Logistic Regression Analysis, Sanku Dey, Sankar Goswami, Madhuchhanda Goswami Jan 2010

Prevalence Of Anaemia In Women Of Reproductive Age In Meghalaya: A Logistic Regression Analysis, Sanku Dey, Sankar Goswami, Madhuchhanda Goswami

Turkish Journal of Medical Sciences

To examine the prevalence of anaemia in Meghalaya, India, by exploring the 2005-2006 National Family Health Survey (NFHS -3) data. Materials and methods: The study population consisted of 3934 ever-married women of reproductive age (15-49 years) from the state Meghalaya, India, which were taken from the NFHS-3 survey, to explore the predictors responsible for the prevalence of anaemia by using different background characteristics such as age, place of residence, nutritional status, number of children ever born, pregnancy status, educational achievement, and economic status. As a response variable, anaemia levels were categorised as a dichotomous variable, and the predicted probabilities were …

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