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Articles 1 - 30 of 137
Full-Text Articles in Medicine and Health Sciences
Peritoneal Dialysis-Related Peritonitis: An Analysis Of Risk Factors In Northeast Anatolia*, Mustafa Keleş, Ramazan Çeti̇nkaya, Abdullah Uyanik, Hami̇t Acemoğlu, Fatma Saatçi, Muhammet Hami̇dullah Uyanik
Peritoneal Dialysis-Related Peritonitis: An Analysis Of Risk Factors In Northeast Anatolia*, Mustafa Keleş, Ramazan Çeti̇nkaya, Abdullah Uyanik, Hami̇t Acemoğlu, Fatma Saatçi, Muhammet Hami̇dullah Uyanik
Turkish Journal of Medical Sciences
Peritonitis is almost the most frequent complication of peritoneal dialysis (PD). Besides being the most frequent reason of hospitalization, peritonitis is also the most important determining factor of mortality-morbidity and technique survival among PD patients. In this study, it was aimed to identify the risk factors for peritonitis in these patients. Materials and methods: In this clinical cohort, records of 218 patients were collected between January 1998 and December 2007. The patients’ demographic, clinical, and laboratory parameters were recorded. Results were analyzed to compare patients who never had peritonitis and patients with at least one episode of peritonitis. Independent predictors …
Serum Adenosine Deaminase Activity And The Total Antioxidant Capacity Of Plasma In Pulmonary Tuberculosis And Non-Tuberculosis Pulmonary Disease, Mohammad Naderi, Mohammad Hashemi, Ali Mehdizadeh, Hamid Mehrabifar, Hamid Reza Kouhpayeh, Hossein Ansari, Gholamreza Bahari, Saeid Ghavami
Serum Adenosine Deaminase Activity And The Total Antioxidant Capacity Of Plasma In Pulmonary Tuberculosis And Non-Tuberculosis Pulmonary Disease, Mohammad Naderi, Mohammad Hashemi, Ali Mehdizadeh, Hamid Mehrabifar, Hamid Reza Kouhpayeh, Hossein Ansari, Gholamreza Bahari, Saeid Ghavami
Turkish Journal of Medical Sciences
The aim of this study was to investigate the level of serum adenosine deaminase (ADA) and the total antioxidant capacity (TAC) in pulmonary tuberculosis (PTB), non-tuberculosis pulmonary disease (non-PTB) and healthy subjects. Materials and methods: Serum ADA activity was measured using the Giusti and Galanti method, and the total antioxidant capacity of plasma was determined by the ferric reducing ability of plasma (FRAP) test. Results: The serum ADA levels were significantly higher (P < 0.001) in pulmonary TB (PTB, 19.78 ± 7.09 U/L), as well as in non-PTB patients (14.78 ± 4.65 U/L) when compared to healthy controls (10.02 ± 1.99 U/L). The sensitivity and specificity were found to be 71.7% and 63.3%, respectively, in distinguishing PTB from non-PTB. In distinguishing PTB from healthy subjects, the sensitivity and specificity were 87% and 93.3%, respectively. The TAC was significantly lower in PTB (485.2 ± 190.0 µM) and non-PTB patients (588.3 ± 195.8 µM), when compared to the controls (784.3 ± 190.0 µM; P < 0.001). Plasma antioxidative activity decreased in PTB and non-PTB patients when compared to the controls. Conclusion: We concluded that serum ADA activity is not a useful test to differentiate pulmonary TB from other respiratory diseases. The TAC is low in pulmonary TB, therefore supplementation with a suitable anti-oxidant may be useful.
Effect Of Essential Hypertension On Qtc Dispersion In Patients With Intracerebral Haemorrhage, Dursun Aygün, Bülent Şi̇şman, Mehmet Seli̇m Nural, Özcan Yilmaz, Ahmet Baydin
Effect Of Essential Hypertension On Qtc Dispersion In Patients With Intracerebral Haemorrhage, Dursun Aygün, Bülent Şi̇şman, Mehmet Seli̇m Nural, Özcan Yilmaz, Ahmet Baydin
Turkish Journal of Medical Sciences
To investigate the effects of essential hypertension on QTc dispersion (QTcd) in patients with intracerebral haematoma (ICH). Materials and methods: This prospective study included adult patients presenting with acute ICH within the first 24 h of ictus to the Emergency Department (ED). On admission, following the first clinical assessment of patients, a complete 12-lead ECG and non-contrast computed tomography (CT) were obtained from each patient. Then, the patients were divided into 2 subgroups according to the presence of hypertension history. The patient groups were compared to each other as well as the control group for QTcd. Results: The study groups …
Comparison Of Remifentanil, Alfentanil, And Fentanil Co-Administered With Propofol To Facilitate Laryngeal Mask Insertion, Ali̇ Sizlan, Uğur Göktaş, Ceyda Özhan, Mehmet Özgür Özhan, Mehmet Emi̇n Orhan, Ercan Kurt
Comparison Of Remifentanil, Alfentanil, And Fentanil Co-Administered With Propofol To Facilitate Laryngeal Mask Insertion, Ali̇ Sizlan, Uğur Göktaş, Ceyda Özhan, Mehmet Özgür Özhan, Mehmet Emi̇n Orhan, Ercan Kurt
Turkish Journal of Medical Sciences
To compare the efficacy of different doses of fentanil, remifentanil, and alfentanil co-administered with propofol in patients undergoing minor surgery. Materials and methods: This double-blind, multi-centered, placebo-controlled study was conducted in 2 medical centers. One hundred forty-one ASA class I and II adult patients aged 18-65 years were included in the study. Patients received i.v. 1 µg kg^{-1} fentanil (group F, n = 33), 10 µg kg^{-1} alfentanil (group A, n = 33), 0.5 µg kg^{-1} remifentanil (group R, n = 36), or saline (control group, n = 39) co-administered with propofol 2.5 mg kg^{-1} without additives over 30 s. …
The Relationship Between Daily Caffeine Consumption And Withdrawal Symptoms: A Questionnaire-Based Study, Nermi̇n Küçer
The Relationship Between Daily Caffeine Consumption And Withdrawal Symptoms: A Questionnaire-Based Study, Nermi̇n Küçer
Turkish Journal of Medical Sciences
To estimate daily caffeine intake among a group of university students at the Kocaeli Vocational School of Health Services in Turkey, and to determine the relationship between daily caffeine consumption and withdrawal symptoms. Materials and methods: This survey study was conducted using a questionnaire that was administered to 156 university students (129 females, 27 males) at the Kocaeli Vocational School of Health Services in Kocaeli, Turkey. The quantity of caffeine-containing products consumed was recorded on a daily basis, depending on the dietary habits of the consumer. The t test for differences between 2 proportions (using the normal approximation) was used …
Four Cases Of Myotonia Congenita In A Turkish Family*, Recep Aygül, Gökhan Özdemi̇r, Di̇lcan Kotan
Four Cases Of Myotonia Congenita In A Turkish Family*, Recep Aygül, Gökhan Özdemi̇r, Di̇lcan Kotan
Turkish Journal of Medical Sciences
Myotonia congenita is a rare muscular disorder with autosomal dominant or autosomal recessive inheritance, and is characterized by painless myotonia. A 44-year-old mother presented at our clinic with a son and a daughter, all sharing the same complaints of difficulty in relaxing their hands and beginning to walk, and spasms during chewing. The family had also another 16-year-old daughter, but she had no such complaints. The mother reported that her father and 2 sisters had the same disease, but that her brother was healthy. Their pedigree analysis revealed that the disease was present for 3 generations and had an autosomal …
Serum Nitric Oxide And Peroxynitrite Levels In Adult Sero-Positive Rheumatoid Arthritis Treated With Disease Modifying Antirheumatic Drugs: A Preliminary Report, Marwan S.M. Al-Nimer, Samir Abdul-Hassan Al-Obaidi, Khalid S. Al-Dulaimi
Serum Nitric Oxide And Peroxynitrite Levels In Adult Sero-Positive Rheumatoid Arthritis Treated With Disease Modifying Antirheumatic Drugs: A Preliminary Report, Marwan S.M. Al-Nimer, Samir Abdul-Hassan Al-Obaidi, Khalid S. Al-Dulaimi
Turkish Journal of Medical Sciences
The contribution of inducible nitric oxide synthase (iNOS) to oxidative/nitrative stress is well documented in inflamed joints. Nitric oxide stimulates the synthesis of proinflammatory mediators and cytotoxic molecules with a pivotal role in apoptosis at the joint of rheumatoid arthritis. This study aimed to assess the serum levels of nitric oxide and peroxynitrite in sero positive rheumatoid patients treated with disease modifying antirheumatic drugs. Materials and methods: Sixteen known patients with sero-positive rheumatoid arthritis fulfilling the criteria of the American College of Rheumatology and on disease modifying antirheumatic drugs were allocated from the consultant clinic of rheumatology at Al-Yarmouk Teaching …
Isolation Of Cryptococcus Neoformans From Pigeon Droppings In Ahwaz, Iran, Majid Zarrin, Masoomeh Jorfi, Nasrin Amirrajab, Morad Rostami
Isolation Of Cryptococcus Neoformans From Pigeon Droppings In Ahwaz, Iran, Majid Zarrin, Masoomeh Jorfi, Nasrin Amirrajab, Morad Rostami
Turkish Journal of Medical Sciences
Cryptococcus neoformans is an opportunistic human pathogen that causes cryptococcosis, a life-threatening infection that is usually manifested as menigeoencephalitis mainly in immunocompromised patients. The objective of this study was to evaluate the presence of Cryptococcus neoformans in Ahwaz, Iran. Materials and methods: Sixty-five samples of pigeon droppings were collected from 10 different regions in Ahwaz. Each sample was suspended 1:10 in saline solution and then cultured in Sabouraud's dextrose agar medium including chloramphenicol. Identification of C. neoformans was performed on the basis of melanin synthesis on bird seed agar, presence of a capsule on India ink preparation, urease production on …
Endometrial Parameters In Ivf And Iui Administration On Elderly Women, Nafi̇ye Yilmaz, Sevtap Kiliç, Yusuf Madendağ, İlknur Madendağ, Ayli̇n Özgün, Gülnur Özakşi̇t, Sertaç Batioğlu
Endometrial Parameters In Ivf And Iui Administration On Elderly Women, Nafi̇ye Yilmaz, Sevtap Kiliç, Yusuf Madendağ, İlknur Madendağ, Ayli̇n Özgün, Gülnur Özakşi̇t, Sertaç Batioğlu
Turkish Journal of Medical Sciences
There are still controversial results about the role of endometrial thickness, pattern, volume, and vascularity in endometrial receptivity. We studied the predictivity of endometrial parameters in endometrial receptivity in over-aged, normogonadotrophic unexplained infertile women. Materials and methods: In this study, 150 women with an age range of 38-42 were included. The patients were divided into 4 groups: group 1 was applied recombinant FSH and intrauterine insemination, group 2 was applied clomiphene citrate and intrauterine insemination, group 3 was applied IVF, and group 4 (control group) was composed of fertile control patients. All patients in each study group had standard initiation …
Underestimated Role Of Alcohol At Skin Disinfection: Lipid Dissolving Property When Used In Association With Conventional Antiseptic Agents, Alp Yentür, İsmet Topçu, Ruşen Işik, Kenan Değerli̇, Süheyla Sürücüoğlu
Underestimated Role Of Alcohol At Skin Disinfection: Lipid Dissolving Property When Used In Association With Conventional Antiseptic Agents, Alp Yentür, İsmet Topçu, Ruşen Işik, Kenan Değerli̇, Süheyla Sürücüoğlu
Turkish Journal of Medical Sciences
After conventional aqueous disinfectant solutions, it was shown that microorganisms were still protected in hair follicles. We hypothesized that those aqueous disinfectant solutions when used in combination with alcohol may be more effective on the inhibition of recolonization of skin and therefore catheter tip colonization. Materials and methods: Skin surface samples were taken from epidural catheter insertion sites prior to catheterization, and before and after disinfection with different combinations of povidone-iodine, chlorhexidine, and alcohol. Before catheter removal, cultures were taken once more and tips of the catheters were cultured. Results: Catheter tip colonization and skin culture results of 10% povidone-iodine …
Endoscopic Biliary Tract Brush Cytology In 54 Cases, Işin Soyuer, Arzu Taşdemi̇r, Şebnem Gürsoy, Alper Yurci̇, Ertuğrul Mavi̇li̇, Nevzat Özcan
Endoscopic Biliary Tract Brush Cytology In 54 Cases, Işin Soyuer, Arzu Taşdemi̇r, Şebnem Gürsoy, Alper Yurci̇, Ertuğrul Mavi̇li̇, Nevzat Özcan
Turkish Journal of Medical Sciences
Duct brushing cytology is an important tool in the evaluation of the extrahepatic biliary tract. New liquid-based preparations and ancillary tests have emerged with the intent of addressing this issue. Materials and methods: Fifty-four consecutive patients and 68 specimens with a suspected malignant obstruction of the common bile duct were included in a consecutive, nonrandomized order. We selected patients whose follow-up, in the form of either histology (25/54, 46%) or at least 6 months of clinical observation, was available. They underwent sampling during ERCP (33 patients/40 materials) or PTC (21 patients/28 materials) using the brush method. Results: A total of …
The Prognostic Value Of Histological Grade In The Outcome Of Patients With Invasive Breast Cancer, Gül Dağlar, Yunus Nadi̇ Yüksek, Ahmet Uğur Gözalan, Tanju Tütüncü, Yeşi̇m Güngör, Nuri̇ Aydin Kama
The Prognostic Value Of Histological Grade In The Outcome Of Patients With Invasive Breast Cancer, Gül Dağlar, Yunus Nadi̇ Yüksek, Ahmet Uğur Gözalan, Tanju Tütüncü, Yeşi̇m Güngör, Nuri̇ Aydin Kama
Turkish Journal of Medical Sciences
Prognostic factors are useful for the prediction of survival in breast cancer patients. According to many studies, tumor size and lymph node stage are the most powerful predictors of tumor behavior. The aim of the present study was to investigate the prognostic value of tumor histological grade. Materials and methods: The study included 214 operable breast cancer patients treated at the same institution that were evaluated to determine the prognostic value of tumor histological grade. Clinico-histopathological features of the patients were also evaluated for overall survival (OS) and disease-free survival (DFS). Results: Tumor histological grade was an independent factor in …
Investigation Of The Causative Agents For Community-Acquired Pneumonia In Adult Patients, Yasemi̇n Zer, Nazan Bayram, İclal Balci, Ayten Fi̇li̇z
Investigation Of The Causative Agents For Community-Acquired Pneumonia In Adult Patients, Yasemi̇n Zer, Nazan Bayram, İclal Balci, Ayten Fi̇li̇z
Turkish Journal of Medical Sciences
Community-acquired pneumonia (CAP) is a common condition in healthy people, causing morbidity and mortality worldwide despite latest advances in therapy and immunization procedures. Causative agents cannot be detected in approximately 50% of CAP episodes and therapy is initiated empirically. We aimed to determine the spectrum and frequency of the causative agents in patients with CAP in a university hospital. Materials and methods: Seventy seven adult patients hospitalized with CAP from November 2007 to March 2008 were included. CAP was diagnosed with clinical, radiological, and laboratory signs. Results: Sputum and blood cultures grew Streptococcus pneumoniae in 15 specimens; Haemophilus influenzae in …
The Efficacy, Safety, And Pharmacokinetics Of Intramuscular And Oral Phenyramidol In Patients With Low Back Pain In An Emergency Department, Hakan Ergün, Onur Polat, N. Arda Demi̇rkan, Müge Günalp, Serdar Gürler
The Efficacy, Safety, And Pharmacokinetics Of Intramuscular And Oral Phenyramidol In Patients With Low Back Pain In An Emergency Department, Hakan Ergün, Onur Polat, N. Arda Demi̇rkan, Müge Günalp, Serdar Gürler
Turkish Journal of Medical Sciences
To compare the efficacy, safety, and pharmacokinetics of oral and intramuscular (i.m.) phenyramidol in patients with low back pain. Materials and methods: Consecutive patients with low back pain were recruited and randomized (5:3) to treatment with either 800 mg oral or i.m. phenyramidol. Pain was assessed by visual analogue scale every 30 min for 2 h. Blood samples were drawn at baseline and every 15 min for 2 h. A 5-point verbal global evaluation scale was performed by both patients and physicians. In addition, the need for rescue analgesics after 2 h was noted. After the acute phase, patients were …
Familial Amyloidosis Cutis Dyschromica, Ayşe Serap Karadağ, Gülçi̇n Güler Şi̇mşek
Familial Amyloidosis Cutis Dyschromica, Ayşe Serap Karadağ, Gülçi̇n Güler Şi̇mşek
Turkish Journal of Medical Sciences
Primary cutaneous amyloidosis is a rare progressive disease that is characterized with the deposition of amyloid under the skin instead of internal organs. Major types are the macular, papular, nodular types. Amyloidosis cutis dyschromica is a very rare specific type of vitiliginous amyloidosis. A 16 year-old female patient and 22 year-old male patient, siblings, referred to the hospital with the complaint of non-pruritic diffuse hyperpigmentation beginning from trunk and spreading to all body. The histopathologic findings and crystal violet stain were consistent with amyloidosis cutis dyschromica. All other investigations were normal. There are few reported cases related with this amyloidosis …
Effects Of Adenosine A1 Receptor Agonist Ccpa And Antagonist Dpcpx On Ischemia/Reperfusion-Induced Arrhythmias In Rats*, Ömer Bozdoğan, Ersöz Gonca, Nuran Ekerbi̇çer
Effects Of Adenosine A1 Receptor Agonist Ccpa And Antagonist Dpcpx On Ischemia/Reperfusion-Induced Arrhythmias In Rats*, Ömer Bozdoğan, Ersöz Gonca, Nuran Ekerbi̇çer
Turkish Journal of Medical Sciences
Adenosine has been commonly used to treat supraventricular tachycardia in clinics. However, there are only a few studies on the effects of adenosine on ischemia or reperfusion induced arrhythmia and they conflict with the results of the present study. During this study, we aimed to clarify the effect of adenosine on ischemia-reperfusion induced arrhythmia. Materials and methods: Left coronary artery was ligated for 6 min and it was released for 15 min to produce reperfusion. A1 adenosine agonist CCPA (2 Chloro - N6 - Cyclopentyl-adenosine), and A1 selective antagonist DPCPX (8 - Cyclopentyl - 1,3 -dipropylxanthine) in 5 µg/kg dose …
Implications Of Socio-Economic Status On The Dietary Fatty Acid Intakes In Turkish Women, Zehra Büyüktuncer, Berat Nursal Tosun, Ayli̇n Ayaz, Makbule Gezmen Karadağ, Alev Kocabaş Keser, Meral Aksoy, Mi̇ne Yurttagül, Sevi̇nç Yücecan, Hali̇t Tanju Besler
Implications Of Socio-Economic Status On The Dietary Fatty Acid Intakes In Turkish Women, Zehra Büyüktuncer, Berat Nursal Tosun, Ayli̇n Ayaz, Makbule Gezmen Karadağ, Alev Kocabaş Keser, Meral Aksoy, Mi̇ne Yurttagül, Sevi̇nç Yücecan, Hali̇t Tanju Besler
Turkish Journal of Medical Sciences
To investigate the effects of socio-economic status (SES) on the dietary intakes of fatty acids in a group of Turkish women. Materials and methods: Five hundred and sixty three women were randomly enrolled into the study. They were classified into 3 SES groups: group 1 high (n = 186), group 2 medium (n = 186), and group 3 low (n = 191). The groups were determined by the SES distribution of Ankara as determined by the 2000 census. Each participant was investigated with a questionnaire consisting of demographic characteristics, physical activity level (24-h record), and dietary intake (24-h recall) by …
Psychological Characteristics Of Adolescent Suicide Attempters Presenting To A Pediatric Emergency Service, Di̇lek Di̇lli̇, Yildiz Dallar, İlyas Çakir
Psychological Characteristics Of Adolescent Suicide Attempters Presenting To A Pediatric Emergency Service, Di̇lek Di̇lli̇, Yildiz Dallar, İlyas Çakir
Turkish Journal of Medical Sciences
To determine the sociodemographic and behavioral characteristics of adolescents who attempt suicide and evaluate them by different scales. Materials and methods: The study was conducted with 116 adolescent suicide attempters and 98 age-matched healthy controls. Results: The mean age of all adolescents was 13.8 ± 1.2 years, with ages ranging from 11 to 16 years. Of these adolescents, 82.7% were girls. The total Suicide Probability Scale score was negatively correlated with the total Reasons for Living Inventory (r = -0.42, P = 0.001) and positively correlated with the Problem Solving Inventory score, which is indicative of low problem-solving capabilities (r …
Protective Effect Of Selenium On Intussusception-Induced Ischemia/Reperfusion Intestinal Oxidative Injury In Rats*, Hülya Akman, Sali̇h Somuncu, Günnur Di̇kmen, Şebnem Ayva, Tutku Soyer, Paki̇ze Doğan, Murat Çakmak
Protective Effect Of Selenium On Intussusception-Induced Ischemia/Reperfusion Intestinal Oxidative Injury In Rats*, Hülya Akman, Sali̇h Somuncu, Günnur Di̇kmen, Şebnem Ayva, Tutku Soyer, Paki̇ze Doğan, Murat Çakmak
Turkish Journal of Medical Sciences
To evaluate the protective effect of selenium on intestinal ischemia-reperfusion injury due to intussusception. Materials and methods: Forty Wistar albino rats were allocated to 4 equal groups (n = 10). After anesthetization, 2 cm of intestinal segment, 20 cm proximal to the ileocecal valve, was removed in the control group (CG). In the intussusception group (ING), intussusception was performed 20 cm proximal to the ileocecal valve by pushing the proximal intestinal segment distally with a stylet, and 2 cm of intestinal segment was removed 4 h later. Intussusception was reduced and a 2 cm segment was removed after another 4 …
Effects Of Grape Consumption On Plasma And Erythrocyte Antioxidant Parameters In Elderly Subjects, Aslihan Avci, Tesli̇me Atli, İmge B. Ergüder, Murat Varli, Erdi̇nç Devri̇m, Özgür Demi̇r, İlker Durak, Murat Turgay
Effects Of Grape Consumption On Plasma And Erythrocyte Antioxidant Parameters In Elderly Subjects, Aslihan Avci, Tesli̇me Atli, İmge B. Ergüder, Murat Varli, Erdi̇nç Devri̇m, Özgür Demi̇r, İlker Durak, Murat Turgay
Turkish Journal of Medical Sciences
To investigate the effects of ingesting Fructus vitis minuta (black grape) on plasma and erythrocyte antioxidant parameters in elderly subjects. Materials and methods: Thirteen subjects (mean age 74.67 ± 0.58) participated in the study. They consumed 1 g/kg body weight per day of dried black Maraş grapes for 1 month. Before and after these periods, fasting blood samples were obtained, and oxidant (as MDA) and antioxidant (as SOD) parameters were studied in erythrocytes. Also, plasma samples were obtained from the subjects. Results: In the erythrocyte hemolysate, MDA (malondialdehydes) levels and SOD (superoxide dismutase) activities were found to be lower (P < 0.01) in the second samples compared to the first ones. Conclusion: We think that because free radical production was decreased SOD activities were not increased. Our results show that reduced peroxidation processes caused by Maraş grape consumption suggest that grape consumption has beneficial effects in elderly subjects.
The Effect Of Microorganisms On Cytokine Secretion From Bone Marrow Dendritic Cells, Işil Fi̇dan, Ayşe Kalkanci, Emi̇ne Yeşi̇lyurt, Berna Erdal, Semra Kuşti̇mur, Turgut İmi̇r
The Effect Of Microorganisms On Cytokine Secretion From Bone Marrow Dendritic Cells, Işil Fi̇dan, Ayşe Kalkanci, Emi̇ne Yeşi̇lyurt, Berna Erdal, Semra Kuşti̇mur, Turgut İmi̇r
Turkish Journal of Medical Sciences
Dendritic cells (DCs) are potent antigen-presenting cells crucial for initiation of cell-mediated immune responses to foreign antigens. They also contribute to the innate resistance against microbial pathogens. The present study examined the effect of microorganisms such as Escherichia coli (E. coli), Serratia marcescens (S. marcescens), Methicillin-resistant Staphylococcus aureus (MRSA), coagulase negative staphylococci (CoNS), and Candida albicans (C. albicans) on cytokine secretion in bone marrow-dendritic cells (BM-DCs). Materials and methods: The levels of cytokines in culture supernatants of the BM-DC were determined by enzyme-linked immunosorbent assay. Results: DCs stimulated by microorganisms produced large amounts of TNF-\alpha, IL-1\beta, IL-6, and IL-10. The …
Comparison Of Quality Of Life In Hepatitis B Virus Carriers Versus Chronic Hepatitis B Virus Carriers Versus The Normal Population, Meltem Işikgöz Taşbakan, Özen Önen Sertöz, Hüsnü Pullukçu, Şebnem Çalik, Oğuz Reşat Si̇pahi̇, Tansu Yamazhan
Comparison Of Quality Of Life In Hepatitis B Virus Carriers Versus Chronic Hepatitis B Virus Carriers Versus The Normal Population, Meltem Işikgöz Taşbakan, Özen Önen Sertöz, Hüsnü Pullukçu, Şebnem Çalik, Oğuz Reşat Si̇pahi̇, Tansu Yamazhan
Turkish Journal of Medical Sciences
To compare health related quality of life (HRQOL) in hepatitis B virus (HBV) carriers versus chronic HBV disease carriers versus the normal population. Materials and methods: The study sample consisted of 2 groups. HBV carriers were recruited from individuals who were regularly followed-up at the Infectious Diseases and Clinical Microbiology outpatient clinic of our setting due to inactivity in HBV infection. The control group was recruited from the same outpatient clinic among patients who had a diagnosis of chronic HBV infection and who were not undergoing active treatment yet. Both groups were requested to fill in the short form 36 …
The Comprehensive Evaluation Of Latent Tuberculosis Infection In Health Care Workers And Of Patients With Active Tuberculosis Using Tst, Elisa, And Elispot Methods, Hülya Şi̇mşek, Si̇bel Meryem Alpar, Kurtuluş Aksu, Funda Aksu, İsmai̇l Ceyhan, Sali̇h Cesur, Ayşegül Gözalan, Mustafa Ertek
The Comprehensive Evaluation Of Latent Tuberculosis Infection In Health Care Workers And Of Patients With Active Tuberculosis Using Tst, Elisa, And Elispot Methods, Hülya Şi̇mşek, Si̇bel Meryem Alpar, Kurtuluş Aksu, Funda Aksu, İsmai̇l Ceyhan, Sali̇h Cesur, Ayşegül Gözalan, Mustafa Ertek
Turkish Journal of Medical Sciences
Until recently, the tuberculin skin test (TST) has been the only assay used for detecting latent tuberculosis infection (LTBI), but two ex-vivo tests, used as alternative methods to TST, based on enumerating the M. tuberculosis-specific interferon (IFN)-\gamma response are now commercially licensed. The aim of this study was to compare the sensitivity and specificity of TST, QuantiFERON Gold (QFT-G), and T-SPOT.TB in diagnosing LTBI and active tuberculosis (TB). Materials and methods: This study was carried out with 95 participants including 3 groups (negative control, close contact, and patient groups) during a 10-month period from March 2007 to January 2008. Results: …
Letter To The Editor, Di̇lşen Çolak, Arzu Akşahi̇n, Mustafa Altinbaş
Letter To The Editor, Di̇lşen Çolak, Arzu Akşahi̇n, Mustafa Altinbaş
Turkish Journal of Medical Sciences
No abstract provided.
Serum Prolidase Activity In Patients With Degenerative And Rheumatic Heart Valve Diseases, Murat Bülent Rabuş, Recep Demi̇rbağ, Yusuf Sezen, Mehmet Taşar, Abdullah Taşkin, Nurten Aksoy, Kaan Kirali̇, Cevat Yakut
Serum Prolidase Activity In Patients With Degenerative And Rheumatic Heart Valve Diseases, Murat Bülent Rabuş, Recep Demi̇rbağ, Yusuf Sezen, Mehmet Taşar, Abdullah Taşkin, Nurten Aksoy, Kaan Kirali̇, Cevat Yakut
Turkish Journal of Medical Sciences
It is known that renin-angiotensin system, inflammation, signaling pathways, and genetic predisposition play a major role in the pathogenesis of heart valve disease. Scarring and collagen deposition in the valves and destruction of myocytes may result from the combined effects of rheumatic and degenerative process in heart valve diseases. Prolidase plays an important role in collagen metabolism, matrix remodeling and cell growth. The aim of the study was to comparatively assess the serum prolidase activity in rheumatic and degenerative heart valve diseases. Materials and methods: The study included 26 patients who had undergone valve replacement due to rheumatic etiology (Group …
The Effects Of 3-Benzoyl-1-Methyl-4-Phenyl-4 Piperidinolhydrochloride (C1), Indomethacin, Nimesulide And Rofecoxib On Cyclooxygenase Activities In Carrageenan-Induced Paw Edema Model, Yaşar Nuri̇ Şahi̇n, Berna Demi̇rcan, Hali̇s Süleyman, Hülya Aksoy, Hali̇se İnci̇ Gül
The Effects Of 3-Benzoyl-1-Methyl-4-Phenyl-4 Piperidinolhydrochloride (C1), Indomethacin, Nimesulide And Rofecoxib On Cyclooxygenase Activities In Carrageenan-Induced Paw Edema Model, Yaşar Nuri̇ Şahi̇n, Berna Demi̇rcan, Hali̇s Süleyman, Hülya Aksoy, Hali̇se İnci̇ Gül
Turkish Journal of Medical Sciences
The aim of this study was to investigate the effects of 3-benzoyl-1-methyl-4-phenyl-4-piperidinol-hydrochloride (C1), which is a structural and also non-classical isomer of bis Mannich base, bis (3-aryl-3-oxo-propyl) methylamine hydrochlorides (B1), on cyclooxygenase (COX) activities in 48 rats with inflammation by using carrageenan-induced paw edema, and to compare its effect with other non-steroidal anti-inflammatory drugs (NSAIDs). Materials and methods: Experimental animals were supplied by the Center of Experimental Research and Practice in Ataturk University. The animals were housed and fed in the laboratory (normal room temparature, food and water) under standard conditions. Rats were randomly assigned to eight groups (n = …
Prevalence Of Anaemia In Women Of Reproductive Age In Meghalaya: A Logistic Regression Analysis, Sanku Dey, Sankar Goswami, Madhuchhanda Goswami
Prevalence Of Anaemia In Women Of Reproductive Age In Meghalaya: A Logistic Regression Analysis, Sanku Dey, Sankar Goswami, Madhuchhanda Goswami
Turkish Journal of Medical Sciences
To examine the prevalence of anaemia in Meghalaya, India, by exploring the 2005-2006 National Family Health Survey (NFHS -3) data. Materials and methods: The study population consisted of 3934 ever-married women of reproductive age (15-49 years) from the state Meghalaya, India, which were taken from the NFHS-3 survey, to explore the predictors responsible for the prevalence of anaemia by using different background characteristics such as age, place of residence, nutritional status, number of children ever born, pregnancy status, educational achievement, and economic status. As a response variable, anaemia levels were categorised as a dichotomous variable, and the predicted probabilities were …
Restricted Universal Guidelines For Rop Screening: A Possible Misguidance For Middle Income Countries, Ömer Erdeve, Begüm Atasay, Saadet Arsan, Fi̇gen Batuoğlu, Huban Ati̇lla, Tomri̇s Türmen
Restricted Universal Guidelines For Rop Screening: A Possible Misguidance For Middle Income Countries, Ömer Erdeve, Begüm Atasay, Saadet Arsan, Fi̇gen Batuoğlu, Huban Ati̇lla, Tomri̇s Türmen
Turkish Journal of Medical Sciences
The objective of all studies evaluating retinopathy of prematurity (ROP) screening criteria has been to minimize the number of infants screened while missing no patients with ROP who required treatment. Studies supporting the recommendation that screening for ROP could be restricted to infants born at less than 30 weeks of gestation with birth weights of less than 1250 g have been reported recently, especially from Western countries. However, with the lack of local outcome data, application of the new restricted screening guidelines to infants in middle income countries may lead to misguidance. We aimed to investigate ROP screening requirements in …
Is The Tanner–Whitehouse (Tw3) Method Sufficiently Reliable For Forensic Age Determination Of Turkish Children?*, Bora Büken, Alp Alper Şafak, Erhan Büken, Burhan Yazici, Zerri̇n Erkol, Ömer Utku Erzengi̇n
Is The Tanner–Whitehouse (Tw3) Method Sufficiently Reliable For Forensic Age Determination Of Turkish Children?*, Bora Büken, Alp Alper Şafak, Erhan Büken, Burhan Yazici, Zerri̇n Erkol, Ömer Utku Erzengi̇n
Turkish Journal of Medical Sciences
The purpose of our study was to determine the accuracy of Tanner-Whitehouse 3 (TW3-RUS) bone age (BA) assessments for forensic age estimations of Turkish children. Materials and methods: Plain radiographs of left hands and wrists of 324 children were evaluated. Mean chronological age (CA) was compared with mean bone age (BA) according to the TW3 atlas for each sex, and differences by age group were determined. Pearson correlation coefficients and cubic regression were used to determine the differences and model the relationships between mean BA and CA. Statistical analyses were carried out using R-project. Results: The difference between the mean …
Predisposing Factors For Serum Sodium Disturbance In Patients With Severe Traumatic Brain Injury (Sbi), Mohammadreza Safavi, Saied Abrishamkar, Poria Tvakoli, Daruosh Moradi, Azim Honarmand
Predisposing Factors For Serum Sodium Disturbance In Patients With Severe Traumatic Brain Injury (Sbi), Mohammadreza Safavi, Saied Abrishamkar, Poria Tvakoli, Daruosh Moradi, Azim Honarmand
Turkish Journal of Medical Sciences
Disturbances in the plasma sodium level in patients with severe brain injury (SBI) is not a rare phenomenon and may cause adverse effects on prognosis and treatment outcomes. The knowledge of the prevalence of risk factors helps in early detection and good management of the serum sodium level disturbance. Materials and methods: This is a prospective clinical trial double blind study. The target population included patients with SBI who had disturbances in their plasma sodium level and were admitted at the ICU of Kashani Hospital, Isfahan, Iran, between January and October 2006. The patients with renal insufficiency, diuretic therapy, massive …