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Articles 2341 - 2370 of 5702
Full-Text Articles in Medicine and Health Sciences
Validation Of Nutrition Standardized Language—Next Steps, Paula Ritter-Gooder, Nancy M. Lewis
Validation Of Nutrition Standardized Language—Next Steps, Paula Ritter-Gooder, Nancy M. Lewis
Department of Nutrition and Health Sciences: Faculty Publications
To provide a model for quality care and outcomes management, the Nutrition Care Process (NCP) and standardized language were introduced in 2003 by the American Dietetic Association (ADA). The standardized language, published in the International Dietetics & Nutrition Terminology (IDNT) Reference Manual: Standardized Language for the Nutrition Care Process, is designed to facilitate communication, improve care, and close the gap in health care quality. When registered dietitians (RDs) are oriented to a nutrition care process, improvement in their documentation of nutrition care occurs. Since the introduction of the NCP and standardized language, RDs and dietetic technicians, registered (DTRs), have …
Initial Experience With A Miniaturized Multiplane Transesophageal Probe In Small Infants Undergoing Cardiac Operations., Sinai C. Zyblewski, Girish S. Shirali, Geoffrey A. Forbus, Tain-Yen Hsia, Scott M. Bradley, Andrew M. Atz, Meryl S. Cohen, Eric M. Graham
Initial Experience With A Miniaturized Multiplane Transesophageal Probe In Small Infants Undergoing Cardiac Operations., Sinai C. Zyblewski, Girish S. Shirali, Geoffrey A. Forbus, Tain-Yen Hsia, Scott M. Bradley, Andrew M. Atz, Meryl S. Cohen, Eric M. Graham
Manuscripts, Articles, Book Chapters and Other Papers
PURPOSE: There has been reluctance to use intraoperative transesophageal echocardiography (TEE) in small infants. We assessed the utility and safety of a new miniaturized multiplane micro-TEE probe in small infants undergoing cardiac operations.
DESCRIPTION: Hemodynamic and ventilation variables were prospectively recorded before and after micro-TEE insertion and removal in infants weighing 5 kg or less undergoing cardiac operations.
EVALUATION: The study included 42 patients with a mean weight of 3.6 +/- 0.9 kg (range, 1.7 to 5 kg). All probe insertions were successful. There were no complications or clinically significant changes in hemodynamic or ventilation variables. Information provided by TEE …
Prostaglandin E(2) Is Crucial In The Response Of Podocytes To Fluid Flow Shear Stress., Tarak Srivastava, Ellen T. Mccarthy, Ram Sharma, Patricia A. Cudmore, Mukut Sharma, Mark L. Johnson, Lynda F. Bonewald
Prostaglandin E(2) Is Crucial In The Response Of Podocytes To Fluid Flow Shear Stress., Tarak Srivastava, Ellen T. Mccarthy, Ram Sharma, Patricia A. Cudmore, Mukut Sharma, Mark L. Johnson, Lynda F. Bonewald
Manuscripts, Articles, Book Chapters and Other Papers
Podocytes play a key role in maintaining and modulating the filtration barrier of the glomerulus. Because of their location, podocytes are exposed to mechanical strain in the form of fluid flow shear stress (FFSS). Several human diseases are characterized by glomerular hyperfiltration, such as diabetes mellitus and hypertension. The response of podocytes to FFSS at physiological or pathological levels is not known. We exposed cultured podocytes to FFSS, and studied changes in actin cytoskeleton, prostaglandin E(2) (PGE(2)) production and expression of cyclooxygenase-1 and-2 (COX-1, COX-2). FFSS caused a reduction in transversal F-actin stress filaments and the appearance of cortical actin …
Age-Related Differences In Perception Of Quality Of Discharge Teaching And Readiness For Hospital Discharge, Kathleen Bobay, Teresa A. Jerofke, Marianne E. Weiss, Olga Yakusheva
Age-Related Differences In Perception Of Quality Of Discharge Teaching And Readiness For Hospital Discharge, Kathleen Bobay, Teresa A. Jerofke, Marianne E. Weiss, Olga Yakusheva
College of Nursing Faculty Research and Publications
No abstract provided.
Physiologically Based Pharmacokinetics Of Molecular Imaging Nanoparticles For Mrna Detection Determined In Tumor-Bearing Mice., Armin W Opitz, Eric Wickstrom, Mathew L Thakur, Norman J Wagner
Physiologically Based Pharmacokinetics Of Molecular Imaging Nanoparticles For Mrna Detection Determined In Tumor-Bearing Mice., Armin W Opitz, Eric Wickstrom, Mathew L Thakur, Norman J Wagner
Kimmel Cancer Center Faculty Papers
Disease detection and management might benefit from external imaging of disease gene mRNAs. Previously we designed molecular imaging nanoparticles (MINs) based on peptide nucleic acids complementary to cancer gene mRNAs. The MINs included contrast agents and analogs of insulin-like growth factor 1 (IGF-1). Analysis of MIN tumor uptake data showed stronger binding in tumors than in surrounding tissues. We hypothesized that MINs with an IGF-1 analog stay in circulation by binding to IGF-binding proteins. To test that hypothesis, we fit the tissue distribution results of several MINs in xenograft-bearing mice to a physiological pharmacokinetics model. Fitting experimental tissue distribution data …
Childhood Obesity: Prevention & Intervention, Carrie Beth Lossing
Childhood Obesity: Prevention & Intervention, Carrie Beth Lossing
Psychology and Child Development
Childhood obesity rates have skyrocketed in the recent years. These trends are alarming since childhood obesity has been linked to numerous health conditions, socioemotional consequences, and academic consequences. This project examines the factors that have been associated with childhood obesity and the consequences of being obese or overweight for children. This project also presents lifestyle changes that parents can make to reduce the likelihood of their children becoming overweight or obese.
Lsuhsc Facilities Daily Update: June 2010, Lsuhsc Property And Facilities Management
Lsuhsc Facilities Daily Update: June 2010, Lsuhsc Property And Facilities Management
LSUHSC Facilities Daily Updates: 2010
LSUHSC Facilities Daily Updates from June 2010.
On the original documents, the daily update for Thursday, June 24, 2010 was misdated as Thursday, June 25, 2010.
These updates describe damage and a timeline of repairs at the LSU Health Sciences Center - New Orleans campus due to Hurricane Katrina which made landfall August 29, 2005.
Lsuhsc Facilities Biweekly Update: June 2010, Lsuhsc Property And Facilities Management
Lsuhsc Facilities Biweekly Update: June 2010, Lsuhsc Property And Facilities Management
LSUHSC Facilities Biweekly Updates: 2010
LSUHSC Facilities Biweekly Updates from June 4 and 18, 2010.
These updates describe damage and a timeline of repairs at the LSU Health Sciences Center - New Orleans campus due to Hurricane Katrina which made landfall August 29, 2005.
Hidden Treasures: Four Great Reasons To Sign Up For An International Mission, Sherylyn Watson
Hidden Treasures: Four Great Reasons To Sign Up For An International Mission, Sherylyn Watson
Nursing Faculty Publications
I am a nurse who has said yes to calls to volunteer internationally for the past 10 years. Whether aiding victims of the tsunami in Sri Lanka and Hurricane Katrina in Mississippi or traveling on prearranged annual mission trips, I discovered personal and professional fulfillment.
A History And One Or Two Things I’Ve Learned, Irvin Sam Schonfeld
A History And One Or Two Things I’Ve Learned, Irvin Sam Schonfeld
Publications and Research
No abstract provided.
The Course Council: An Example Of Student-Centered Learning, Deborah Himes, Barbara Heise
The Course Council: An Example Of Student-Centered Learning, Deborah Himes, Barbara Heise
Faculty Publications
To promote student-centered learning, a course council was established in a beginning undergraduate nursing course. A student representative was selected by peers to attend a monthly course council meeting with faculty. Representatives were asked to query classmates in their section of eight students regarding opinions, questions, and concerns about the course and then bring those views to the council. In this monthly, small group, open dialogue setting, students spoke freely about experiences in the classroom, laboratory, and clinical settings. The stage was set for reflection, problem solving, and decision making involving students and faculty. Student input led to meaningful course …
Age And Load Compliance Alter Time To Task Failure For A Submaximal Fatiguing Contraction With The Lower Leg, Erin E. Griffith, Tejin Yoon, Sandra K. Hunter
Age And Load Compliance Alter Time To Task Failure For A Submaximal Fatiguing Contraction With The Lower Leg, Erin E. Griffith, Tejin Yoon, Sandra K. Hunter
Exercise Science Faculty Research and Publications
The purpose of this study was to compare the time to failure and muscle activation of young and old adults for a sustained isometric submaximal contraction with the dorsiflexor muscles when the foot was restrained to a force transducer (force-control task) compared with supporting an equivalent inertial load unrestrained in the sagittal plane (position-control task). Seventeen young (23.6 ± 6.5 yr) and 12 old (70.0 ± 5.0 yr) adults performed the force-control and position-control tasks at 30% maximal voluntary contraction (MVC) until task failure on separate days. Despite the similar load torque for each task, time to failure was longer …
What Do You See In This Picture?: Bias And Reflexivity In Physician Narratives Of Disparities, Michelle Levine
What Do You See In This Picture?: Bias And Reflexivity In Physician Narratives Of Disparities, Michelle Levine
Graduate Masters Theses
Disparities in healthcare stem from historical, social, institutional, and interpersonal factors--all of which can manifest at the level of the clinical encounter. A growing body of research has addressed implicit bias and, more specifically, the implicit bias involved in aversive racism as a mediator of disparate care. While recent studies have suggested links between disparate treatment and implicit bias, little direct evidence exists for how implicit bias may effect disparate care. Qualitative research on physician understanding of processes by which implicit bias translates into disparate care can help fill this gap and identify areas for further research. This study conducted …
Myxomatous Degenerative Mitral Valve Disease: An Update, Sirilak Disatian
Myxomatous Degenerative Mitral Valve Disease: An Update, Sirilak Disatian
The Thai Journal of Veterinary Medicine
Myxomatous degenerative mitral valve disease (MVD) is the most common cardiac disease in dogs.Pathological changes of MVD include thickened redundant leaflets causing improper coaptation of leaflets, resultingin mitral valve regurgitation. The etiology of this disease is currently unknown. Thus, no drugs or treatments areavailable to slow down the disease progression. This article was written to summarize an update of canine MVD concerning clinical approach, etiology, and treatment.
Comparison Of Carprofen, Vedaprofen And Tepoxalin For Postoperative Analgesia And Serum Pge2 Level In Dogs After Ovariohysterectomy, Naris Thengchaisri, Panpicha Sattasathuchana, Sirirat Niyom, Wannasit Chantornvong
Comparison Of Carprofen, Vedaprofen And Tepoxalin For Postoperative Analgesia And Serum Pge2 Level In Dogs After Ovariohysterectomy, Naris Thengchaisri, Panpicha Sattasathuchana, Sirirat Niyom, Wannasit Chantornvong
The Thai Journal of Veterinary Medicine
Comparison of analgesic efficacy of 3 non-steroidal analgesic drugs (carprofen, vedaprofen and tepoxalin) were performed in 40 dogs after ovariohysterectomy. Oral administration of placebo (sugar pill), carprofen (4.4 mg/kg/day), vedaprofen (0.5 mg/kg/day), or tepoxalin (20 mg/kg/day) for 3 days were performed in dogs recovering from ovariohysterectomy. Numerical pain scores (descriptive and composite pain scores) were measured in blinded fashion by three investigators at 0, 12, 24, 36, 48 and 60 hrs following the recovery. The average descriptive and composite pain scores of dogs treated with carprofen or tepoxalin were significantly lower than that of the control group (p<0.05), however, no significance difference was found between the vedaprofen-treated and control groups (p>0.05). Serum …0.05),>
Effect Of Water Temperature On Hematology And Virulence Of Aeromonas Hydrophila In Hybrid Catfish (Clarias Gariepinus Burchell X C. Macrocephalus Gunther), Weena Koeypudsa, Malinee Jongjareanjai
Effect Of Water Temperature On Hematology And Virulence Of Aeromonas Hydrophila In Hybrid Catfish (Clarias Gariepinus Burchell X C. Macrocephalus Gunther), Weena Koeypudsa, Malinee Jongjareanjai
The Thai Journal of Veterinary Medicine
Water temperature was set up at 2 levels; high (Ht, 29.5±0.5oC) and low temperature (Lt, 19.5±0.5oC). Experimental catfish body weight and total length were 12.07±1.41 g and 11.57±0.62 cm respectively. Catfish were divided into 4 groups: high temperature with 0.1% sodium chloride (NaCl) (HtWs), high temperature without 0.1% NaCl (HtW/s), low temperature with 0.1% NaCl (LtWs), and low temperature without 0.1% NaCl (LtW/s). Catfish hematocrit (Hct) and clinical chemistry including serum glutamic oxaloacetic transminase (SGOT), serum glutamic pyruvic transaminase (SGPT), alkaline phosphatase (ALP), blood urea nitrogen (BUN), and creatinine (Cr) were measured. The results showed that water temperature, Ht (HtWs …
The Sperm Dna Damage After Cryopreservation Of Boar Semen In Relation To Post-Thawed Semen Qualities, Antioxidant Supplementation And Boars Effects, Panida Chanapiwat, Kampon Kaeoket, Padet Tummaruk
The Sperm Dna Damage After Cryopreservation Of Boar Semen In Relation To Post-Thawed Semen Qualities, Antioxidant Supplementation And Boars Effects, Panida Chanapiwat, Kampon Kaeoket, Padet Tummaruk
The Thai Journal of Veterinary Medicine
The objectives of the present study were to evaluate the damage of DNA of the frozen-thawed (FT) boar spermatozoa and to investigate the effect of various concentrations of L-cysteine supplementation on the sperm DNA damage. A total of 104 cryopreserved semen samples from twenty-six ejaculates of 16 proven boars were analyzed. Of these samples, each semen sample contained a different concentration of L-cysteine i.e., 0 (n=41), 5 (n=41), 10 (n=11) and 15 (n=11) mM. All of the semen samples were cryopreserved by controlled-rate freezer. The semen was thawed at 50oC for 12 sec and the damage to the sperm DNA …
Clinical, Radiographic And Pathological Features Of Persistent Gastroesophageal Intussusception In An Adult Dog: A Case Report, Theerayuth Kaewamatawong, Wijit Banlunara, Varaporn Wangrattanaparanee, Srireepong Kiertkrittikhoon
Clinical, Radiographic And Pathological Features Of Persistent Gastroesophageal Intussusception In An Adult Dog: A Case Report, Theerayuth Kaewamatawong, Wijit Banlunara, Varaporn Wangrattanaparanee, Srireepong Kiertkrittikhoon
The Thai Journal of Veterinary Medicine
The aim of this report is to describe the clinical, radiographic and pathological appearances of a persistent gastroesophageal intussusception in associated with idiopathic egaesophagus in an adult dog. A 6-years old, male Golden Retriever was referred for evaluation of chronic regurgitation and vomiting. Radiographic diagnosis of persistent gastroesophageal intussusception (GEI) with megaesophagus was made. Survey and contrast radiography evidenced a distension of the esophageal medial and caudal portions due to a dense soft-tissue mass and the barium cloud not pass to abdominal portion, where outlined the striations of muscle of the distal esophagus around the mass.Necropsy findings revealed a completed …
Splenic Infarction: An Update On William Osler's Observations., Yaacov R Lawrence, Ma Mbbs Mrcp, Russell Pokroy, Mb Bch, Daniel Berlowitz, Mb Bch, Dvora Aharoni, Md, Daniel Hain, Md, Gabriel S Breuer, Md
Splenic Infarction: An Update On William Osler's Observations., Yaacov R Lawrence, Ma Mbbs Mrcp, Russell Pokroy, Mb Bch, Daniel Berlowitz, Mb Bch, Dvora Aharoni, Md, Daniel Hain, Md, Gabriel S Breuer, Md
Department of Radiation Oncology Faculty Papers
BACKGROUND: Osler taught that splenic infarction presents with left upper abdominal quadrant pain, tenderness and swelling accompanied by a peritoneal friction rub. Splenic infarction is classically associated with bacterial endocarditis and sickle cell disease.
OBJECTIVES: To describe the contemporary experience of splenic infarction.
METHODS: We conducted a chart review of inpatients diagnosed with splenic infarction in a Jerusalem hospital between 1990 and 2003.
RESULTS: We identified 26 cases with a mean age of 52 years. Common causes were hematologic malignancy (six cases) and intracardiac thrombus (five cases). Only three cases were associated with bacterial endocarditis. In 21 cases the splenic …
Establishing Normal Psychoacoustic Parameters Using Adaptive Procedures For The Clinical Assessment Of Psychoacoustic Phenomenon, Maria Noelle Burnham
Establishing Normal Psychoacoustic Parameters Using Adaptive Procedures For The Clinical Assessment Of Psychoacoustic Phenomenon, Maria Noelle Burnham
Theses and Dissertations
Masking Level Difference (MLD) tests are an established component of auditory processing test batteries; however, normative data for these tests vary according to procedure. In this study, forty normal, native-English speaking adults between the ages of 18 and 26 were tested for MLD via a newly developed computer software program using both an adaptive procedure (MLDA) and a Bekesy procedure (MLDB). The results from the two procedures were analyzed for sex differences and compared with each other. For both the MLDA and MLDB, the results showed statistically significant sex differences in the masked thresholds used to obtain the MLD (NoSo …
Evolutionary Conservation Of Residues In Vertebrate Dna Polymerase N Conferring Low Fidelity And Bypass Activity, Kei-Ichi Takata, Mercedes E Arana, Mineaki Seki, Thomas A Kunkel, Richard D Wood
Evolutionary Conservation Of Residues In Vertebrate Dna Polymerase N Conferring Low Fidelity And Bypass Activity, Kei-Ichi Takata, Mercedes E Arana, Mineaki Seki, Thomas A Kunkel, Richard D Wood
Faculty, Staff and Student Publications
POLN is a nuclear A-family DNA polymerase encoded in vertebrate genomes. POLN has unusual fidelity and DNA lesion bypass properties, including strong strand displacement activity, low fidelity favoring incorporation of T for template G and accurate translesion synthesis past a 5S-thymine glycol (5S-Tg). We searched for conserved features of the polymerase domain that distinguish it from prokaryotic pol I-type DNA polymerases. A Lys residue (679 in human POLN) of particular interest was identified in the conserved 'O-helix' of motif 4 in the fingers sub-domain. The corresponding residue is one of the most important for controlling fidelity of prokaryotic pol I …
Stroke Registry: A Developing Country's Perspective., Farrukh S. Khan, Maimoona Siddiqui, Hazim Brohi, Khurram A. Siddiqui
Stroke Registry: A Developing Country's Perspective., Farrukh S. Khan, Maimoona Siddiqui, Hazim Brohi, Khurram A. Siddiqui
Section of Neurology
No abstract provided.
High Dose Atorvastatin After Stroke Or Transient Ischaemic Attack (Sparcl)--Does Every Stroke Patient In Pakistan Deserve A Statin, Maria Khan, Ayeesha Kamran Kamal
High Dose Atorvastatin After Stroke Or Transient Ischaemic Attack (Sparcl)--Does Every Stroke Patient In Pakistan Deserve A Statin, Maria Khan, Ayeesha Kamran Kamal
Section of Neurology
No abstract provided.
Regulation Of Pim1 Under Hypoxia In Prostate Cancer, Eva Sahakian
Regulation Of Pim1 Under Hypoxia In Prostate Cancer, Eva Sahakian
Loma Linda University Electronic Theses, Dissertations & Projects
A defining characteristic of solid tumors is the capacity to divide and spread under conditions of nutrient deprivation and limited oxygen availability. These microenvironmental stresses arise from structural abnormalities in tumor vessels that lead to aberrant microcirculation. Hypoxia acts as a physiological “selection pressure” in the progression of cancer by activating pathways and enhancing the expression of specific genes in tumor cells which eventually diminish their apoptotic potential. Ultimately, hypoxic microenvironment functions as a “stress factor”, selecting cells with the ability to survive and divide under anoxic conditions. The members of the PIM family of cytoplasmic serine threonine kinases are …
Roadmap Of Torture: Captive Thai Elephant And The Anecdote, Sumolya Kanchanapangka
Roadmap Of Torture: Captive Thai Elephant And The Anecdote, Sumolya Kanchanapangka
The Thai Journal of Veterinary Medicine
No abstract provided.
Characterization And Probiotic Properties Of Bacillus Strains Isolated From Broiler, Neungnut Chaiyawan, Punnathorn Taveeteptaikul, Bhusita Wannissorn, Supatjaree Ruengsomwong, Prapaipat Klungsupya, Wannaluk Buaban, Pariyaporn Itsaranuwat
Characterization And Probiotic Properties Of Bacillus Strains Isolated From Broiler, Neungnut Chaiyawan, Punnathorn Taveeteptaikul, Bhusita Wannissorn, Supatjaree Ruengsomwong, Prapaipat Klungsupya, Wannaluk Buaban, Pariyaporn Itsaranuwat
The Thai Journal of Veterinary Medicine
In order to isolate local strain of spore-forming bacteria having probiotic properties, 164 isolates of the sporeforming bacteria were isolated from 152 samples including duodenum, jejunum, ileum and cecum collected from 38 local backyard chickens raised in the northern part of Thailand. These isolates were preliminarily screened for antibiotic susceptibility and antimicrobial acitivity. Only antibiotic-susceptible isolates with antimicrobial activity were further characterized for the ability to resist certain harsh environments. Identification of the potential isolates was carried out by morphological and biochemical studies, followed by analysis of 16S rDNA sequence. Of these isolates, only one strain designated T3-1 showed antimicrobial …
Ecg Quiz, Chollada Buranakarl, Monkon Trisiriroj
Ecg Quiz, Chollada Buranakarl, Monkon Trisiriroj
The Thai Journal of Veterinary Medicine
No abstract provided.
A Direct Role For Secretory Phospholipase A2 And Lyso-Phosphatidylcholine In The Mediation Of Lipopolysaccharide-Induced Gastric Injury, Elizabeth J Dial, Duy M Tran, Jimmy J Romero, Mayssa Zayat, Lenard M Lichtenberger
A Direct Role For Secretory Phospholipase A2 And Lyso-Phosphatidylcholine In The Mediation Of Lipopolysaccharide-Induced Gastric Injury, Elizabeth J Dial, Duy M Tran, Jimmy J Romero, Mayssa Zayat, Lenard M Lichtenberger
Faculty, Staff and Student Publications
Endotoxemia from sepsis can injure the gastrointestinal tract through mechanisms that have not been fully elucidated. We have shown that LPS induces an increase in gastric permeability in parallel with the luminal appearance of secretory phospholipase A2 (sPLA2) and its product, lysophosphatidylcholine (lyso-PC). We proposed that sPLA2 acted on the gastric hydrophobic barrier, composed primarily of phosphatidylcholine (PC), to degrade it and produce lyso-PC, an agent that is damaging to the mucosa. In the present study, we have tested whether lyso-PC and/or sPLA2 have direct damaging effects on the hydrophobic barriers of synthetic and mucosal surfaces. Rats were administered LPS …
Progressive Regression Of Left Ventricular Hypertrophy Two Years After Bariatric Surgery, Mohamed F Algahim, Thomas R Lux, Joshua G Leichman, Anthony F Boyer, Charles C Miller, Susan T Laing, Erik B Wilson, Terry Scarborough, Sherman Yu, Brad Snyder, Carol Wolin-Riklin, Ursula G Kyle, Heinrich Taegtmeyer
Progressive Regression Of Left Ventricular Hypertrophy Two Years After Bariatric Surgery, Mohamed F Algahim, Thomas R Lux, Joshua G Leichman, Anthony F Boyer, Charles C Miller, Susan T Laing, Erik B Wilson, Terry Scarborough, Sherman Yu, Brad Snyder, Carol Wolin-Riklin, Ursula G Kyle, Heinrich Taegtmeyer
Faculty, Staff and Student Publications
BACKGROUND: Obesity is a systemic disorder associated with an increase in left ventricular mass and premature death and disability from cardiovascular disease. Although bariatric surgery reverses many of the hormonal and hemodynamic derangements, the long-term collective effects on body composition and left ventricular mass have not been considered before. We hypothesized that the decrease in fat mass and lean mass after weight loss surgery is associated with a decrease in left ventricular mass.
METHODS: Fifteen severely obese women (mean body mass index [BMI]: 46.7+/-1.7 kg/m(2)) with medically controlled hypertension underwent bariatric surgery. Left ventricular mass and plasma markers of systemic …
Cellular Dynamic Simulator: An Event Driven Molecular Simulation Environment For Cellular Physiology, Michael J Byrne, M Neal Waxham, Yoshihisa Kubota
Cellular Dynamic Simulator: An Event Driven Molecular Simulation Environment For Cellular Physiology, Michael J Byrne, M Neal Waxham, Yoshihisa Kubota
Faculty, Staff and Student Publications
In this paper, we present the Cellular Dynamic Simulator (CDS) for simulating diffusion and chemical reactions within crowded molecular environments. CDS is based on a novel event driven algorithm specifically designed for precise calculation of the timing of collisions, reactions and other events for each individual molecule in the environment. Generic mesh based compartments allow the creation / importation of very simple or detailed cellular structures that exist in a 3D environment. Multiple levels of compartments and static obstacles can be used to create a dense environment to mimic cellular boundaries and the intracellular space. The CDS algorithm takes into …