Medicine and Health Sciences Commons^™

Traumatic Dural Venous Sinus Thrombosis In High-Risk Acute Blunt Head Trauma Patients, W. Akhtar

Department of Radiology

No abstract provided.

What Is The Best Antiplatelet Agent For Prevention Of Recurrent Stroke In Pakistani Patients? Do Combinations Offer Significant Advantages In The South Asian Context?, Maria Khan, Ayeesha Kamran Kamal

Section of Neurology

No abstract provided.

Molecular Requirements For Ethanol Differential Allosteric Modulation Of Ligand-Gated Ion Channels Based On Selective Gβγ Modulation, Gonzalo E. Yevenes, Gustavo Moraga-Cid, Ariel Avila, Leonardo Guzman, Maximiliano Figueroa, Robert W. Peoples, Luis G. Aguayo

Biomedical Sciences Faculty Research and Publications

It is now believed that the allosteric modulation produced by ethanol in glycine receptors (GlyRs) depends on alcohol binding to discrete sites within the protein structure. Thus, the differential ethanol sensitivity of diverse GlyR isoforms and mutants was explained by the presence of specific residues in putative alcohol pockets. Here, we demonstrate that ethanol sensitivity in two LGIC members, the GlyR adult α₁ and embryonic α₂ subunits, can be modified through selective mutations that rescued or impaired Gβγ modulation. Even though that both isoforms were able to physically interact with Gβγ, only the α₁ GlyR was functionally …

Effects Of Orthodontic Treatment On Social Perceptions, Sherry A. Caraveo

Loma Linda University Electronic Theses, Dissertations & Projects

Introduction: The purpose of this study was to record first impressions elicited by photographs of orthodontic patients before and after treatment to test the hypothesis that after treatment patients will elicit a more positive first impression.

Methods and Materials: Before (Tl) and After (T2) photographs of six orthodontic patients equally divided by gender and standardized for background facial attractiveness were selected. Three different malocclusions were represented: 1) Class 1 crowded, 2) Class 11 div 1, and 3) Class 111. 108 college students rated each photographed patient on three attributes: physical attractiveness, intelligence and social desirability. Participants recorded their responses on …

Psychological Profiles In A Female Bariatric Surgery Sample, Aimee L. Donato

Loma Linda University Electronic Theses, Dissertations & Projects

Morbid obesity is an epidemic. Current literature suggests that people with morbid obesity tend to show increased levels of psychological dysfunction. This is especially pertinent to the clinicians who work with morbidly obese patients who seek bariatric surgery as the method for weight control. Surgery should be performed on patients who are psychologically ready to adjust to the stringent post-operative lifestyle.

The purpose of the present study was (1) to compare two groups of bariatric patients (a White group and a non-White group) on pre-surgery measures: specific scales on the Millon Behavioral Medicine Diagnostic (MBMD), the Beck Depression Inventory II …

Forensic Veterinary Medicine, Nantarika Chansue

The Thai Journal of Veterinary Medicine

No abstract provided.

Comparative Study On Six Different Long Term Commercial Extenders For Fresh Boar Semen, Kampon Kaeoket, Titisa Srisowanna, Ubonrat Wichaidit, Panida Chanapiwat, Sukanya Manee-In

The Thai Journal of Veterinary Medicine

In Thailand, there are numerous commercial extenders for preservation of boar semen; however, no study has been carried out to compare these extenders in view of maintaining of sperm motility, plasma membrane integrity and acrosome integrity during cold storage. The aim of this study was to assess the percentage of sperm motility, HOST positive, viability and acrosome integrity of boar spermatozoa extended in Merck-III, Androstar®Plus, ModenaTM, NUTRIXcell®, VITASEM LD, Duragen and Dofu goldTM. Ejaculated from boars (n=6, one ejaculate from each boar) were collected and sub-samples (splited samples) were diluted (3x109 spermatozoa/100 ml) in the different extenders and stored for …

Establishment Of Porcine Embryonic Stem-Like Cells From Parthenogenetic And In Vivo Derived Embryos, Sasithorn Panasophonkul, Theerawat Tharasanit, Mongkol Techakumphu

The Thai Journal of Veterinary Medicine

The study was conducted to examine the effect of different parthenogenetic activation (PA) protocols on developmental competence and quality of embryos, and to establish the parthenogenetic embryonic stem (ptES)-like cells in pigs. Compacted cumulus-oocyte complexes (COCs) were collected from porcine ovaries and then cultured in M199-medium. After 44 hrs of culture, matured MII-oocytes were selected and divided into three groups. Oocytes in each group were stimulated with three different activation protocols as protocol I: 1.36 kV/cm, 30 μsec, 2 pulses; protocol II: 1.50 kV/cm, 60 μsec, 2 pulses and protocol III: 1.0 kV/cm, 80 μsec, 3 pulses, and followed by …

Sano (Sesbania Javanica Miq.) Flower As A Pigment Source In Egg Yolk Of Laying Hens, Suwanna Kijparkorn, Hatairat Plaimast, Somporn Wangsoonoen

The Thai Journal of Veterinary Medicine

The study was conducted to investigate Sano flower that naturally contains high concentration of yellow fat soluble pigment as a pigment source for egg yolk in layer diet. Dried Sano flower (Sano) was prepared and analyzed for nutritional composition and total carotenoids content. Six dietary treatments were: 1) corn-soy basal diet that contain total carotenoids from corn at 12 mg/kg diet, 2)-4) Sano diet that contain total carotenoids from Sano at 10, 15 and 30 mg/kg diet, 5) mixed carotenoids diet that contain total carotenoids from Sano at 10 mg/kg and synthetic pigment, canthaxanthin at 2 mg/kg diet, and 6) …

Evaluation Of Serum Nt-Probnp Levels In Dogs With Respiratory Distress Associated With Heart Disease And Respiratory Disease, Amornrate Sastravaha, Santi Kaewmokul, Pareeya Udomkusonsri, Naris Thengchaisri

The Thai Journal of Veterinary Medicine

The association between severity of heart disease and serum N-terminal prohormone B-type natriuretic peptide (NT-proBNP) was determined in dogs presented with respiratory distress. Four groups of dogs were divided into healthy control (n=11), heart failure (n=58), heart disease without heart failure (n=17) and respiratory disease (n=20). Serum NT-proBNP concentrations were measured with an ELISA designed for using in dogs. Dirofilaria antigen tests were detected in dogs with heart disease or heart failure. Serum NT-proBNP concentrations of dogs with heart failure (2,977±184 pmol/l) were significantly higher than dogs with heart disease (611±46 pmol/l), respiratory disease (583±52 pmol/l) or physically healthy (426±32 …

Analysis On The Polymorphism And The Genetic Effects On Some Economic Traits Of Mx Gene S631n Mutation Site In Chicken, Luan De Qin, Bin Chang Guo, Wei Sheng Zhong, Liu Yan, Hong Chen Guo

The Thai Journal of Veterinary Medicine

PCR-RFLP technique was performed to detect the distribution differences of the resistant and sensitive alleles of S631N site of Mx gene in 8 chicken populations. The results showed the average frequencies of resistant allele A and sensitive allele G were 0.4995 and 0.5005, respectively, and the average value of observed heterozygosis and Shannon’s index were 0.6163 and 0.5232. Three populations were in Hardy-Weinberg equilibrium at this site (p>0.05). The Ewens-Watterson test indicated that this site was neutral in all the other populations except for Rugao. The dendrograms based on allele frequency divided the 8 populations into 3 clusters, which …

The Contribution Of Active Efflux In Reduced Susceptibilities To Copper Sulfate And Zinc Chloride In Escherichia Coli Isolates From Swine, Chailai Koowatananukul, Nisit Chansong, Rungtip Chuanchuen

The Thai Journal of Veterinary Medicine

A hundred-eighty Escherichia coli isolates from swine were tested for minimal inhibitory concentrations (MICs) of 9 antimicrobials and two heavy metals copper sulfate and zinc chloride. All the E. coli isolates were resistant to at least one antibiotic and 175 (97.2%) isolates were multi-drug resistant. Forty antibiotic resistance patterns were identified, of which the most common pattern was AMP-CHP-CIP-ERY-GEN-STR-SUL-TET-TRI (13.3%). All the isolates formed one large population of susceptibility to copper sulfate and zinc chloride at the concentrations of 6.4-12.8 mM and 3.2-6.4 mM, respectively. Exposure to copper sulfate and zinc chloride at sublethal concentration did not change the susceptibility. …

Blood Pressure, Urinary Protein Creatinine Ratio And Oxidative Stress In Dogs With Urolithiasis, Supa Sithanukul, Poramin Shayarattanasin, Vimolpa Hiranpradith, Winai Chansaisakorn, Monkon Trisiriroj, Siripen Komolvanich, Saikaew Satayatham, Chollada Buranakarl

The Thai Journal of Veterinary Medicine

Blood pressure, urinary protein creatinine (UPC) ratio and oxidative stress (plasma melondialdehyde, urinary melondialdehyde creatinine ratio; UMDA/Cr, the activities of red blood cell catalase; RBC-CAT and red blood cell glutathione) were studied in 42 dogs with urolithiasis and 14 control healthy dogs. The types and location of calculi were defined. The results showed that calculi preferentially found in male and female dogs were calcium oxalate and struvite, respectively. In female, calculi found mostly at urinary bladder while in male, they could be found in either urinary bladder and/or urethra. Dogs with urolithiasis were normotensive. However, UPC ratio was higher significantly …

Ophthalmology Snapshot, Nalinee Tuntivanich

The Thai Journal of Veterinary Medicine

No abstract provided.

Ultrasound Diagnosis, Phiwipha Kamonrat

The Thai Journal of Veterinary Medicine

No abstract provided.

Clinical–Pathological Conference: Case 2, Nasser Said-Al-Naief, Molly S. Rosebush, Denis P. Lynch

School of Dentistry Faculty Research and Publications

No abstract provided.

Predictors Of Obesity Among Post Graduate Trainee Doctors Working In A Tertiary Care Hospital Of Public Sector In Karachi, Pakistan, Sajid Mahmood, Muhammad Kazim Rahim Najjad, Nasir Ali, Naeem Yousuf, Yasir Hamid

Community Health Sciences

Objectives: To identify the predictors of obesity among post graduate trainee doctors working in a tertiary care hospital of public sector at Karachi, Pakistan.
Methods: A cross sectional analytical study was conducted at one of the tertiary care hospitals of public sector in Karachi. Information was collected from 117 post graduate trainee doctors via pre-tested self administered questionnaire and standard tools were used for height and weight measurement. Obesity was defined as body mass index (BMI) > or =23 by using South Asian cut-off points. SPSS version 16 was used for data analysis, and logistic regression technique was applied to come …

Soft Tissue Grafting To Improve Implant Esthetics, Moawi M. Kassab

School of Dentistry Faculty Research and Publications

Dental implants are becoming the treatment of choice to replace missing teeth, especially if the adjacent teeth are free of restorations. When minimal bone width is present, implant placement becomes a challenge and often resulting in recession and dehiscence around the implant that leads to subsequent gingival recession. To correct such defect, the author turned to soft tissue autografting and allografting to correct a buccal dehiscence around tooth #24 after a malpositioned implant placed by a different surgeon. A 25-year-old woman presented with the chief complaint of gingival recession and exposure of implant threads around tooth #24. The patient received …

Creating A Lymphedema Wellness Culture, Nancy Kinzli Ms, Otr/L, Clt-Lana

Department of Medicine

No abstract provided.

Efficacy Of Morning-Only Compared With Split-Dose Polyethylene Glycol Electrolyte Solution For Afternoon Colonoscopy: A Randomized Controlled Single-Blind Study., Rebecca Matro, Md, Anastasia Shnitser, Md, Maya Spodik, Md, Constantine Daskalakis, Sc.D, Leo Katz, Md, Alexandra Murtha, Ba, David Kastenberg, Md

Division of Internal Medicine Faculty Papers & Presentations

OBJECTIVES: Administering a purgative close to the time of colonoscopy is optimal for cleansing. The aim of this study was to compare the efficacy and tolerability of morning-only (AM-only) polyethylene glycol electrolyte solution (PEG-ELS) to split-dose (PM/AM) PEG-ELS for afternoon colonoscopy.

METHODS: This was a single-center, prospective, randomized, investigator-blinded, non-inferiority study comparing AM-only to PM/AM PEG-ELS for afternoon outpatient colonoscopy. The primary end point was whole colon prep adequacy. Tolerance and polyp detection were secondary outcomes.

RESULTS: Overall, 125 patients were randomized and 9 withdrew without taking any prep. Of 116 analyzed, 62 received AM-only prep and 54 received PM/AM …

One And Only Campaign Nevada Evaluation Of Educational Materials For Injection Safety Executive Summary, Nevada Institute For Children’S Research And Policy, School Of Community Health Science, University Of Nevada, Las Vegas, Amanda Haboush, Tara Phebus, Kari Wolkwitz, Denise Tanata Ashby, Enrique Lopez, Christopher M. Aquino, Sheila Clark

Nevada Institute for Children's Research and Policy Reports

The goal of the evaluation was to measure the effectiveness of the Campaign’s educational materials in raising awareness among the general public and enhancing the knowledge of healthcare personnel. Through this measurement the evaluation results would then also provide recommendations for improvements to the materials. To achieve these goals the evaluation team at NICRP created a strategic dissemination plan designed to support a formal evaluation of messages within the materials, message delivery and general knowledge and understanding of safe injection practices by both providers and the general public. Methods utilized to conduct this evaluation included:

• Surveys of both patients and …

Identification Of A Unique Core Domain Of Par-4 Sufficient For Selective Apoptosis Induction In Cancer Cells, Vivek M. Rangnekar

Radiation Medicine Faculty Patents

The present invention relates to Par-4 mutants which cause apoptosis in cancer cells which are sensitive to Par-4 and also induce apoptosis in cancer cells which are resistant to Par-4. The present invention also relates to methods of using the Par-4 mutant to treat certain cancers, as well as to kits, vectors, and polypeptides for same.

My Friend, The Fast Lane, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.

Core Promoter Function In Brugia Malayi, Michelle Bailey

USF Tampa Graduate Theses and Dissertations

Previous studies have indicated that the promoters of the human filarial parasite Brugia malayi are unusual in that they do not exhibit the CAAT or TATAA sequences usually found in the core domains of promoters of most eukaryotic organisms. Analysis of the promoters of the ribosomal proteins showed that the region flanking the splice leader (SL) addition site plays an important role in transcription and may function as the core promoter domain in B. malayi. To test the hypothesis that the SL addition domain is the most important essential region of the ribosomal protein promoters, the SL addition site of …

Ranolazine Is Effective For Acute Or Chronic Ischemic Dysfunction With Heart Failure, Sudip Nanda Md, Facp, Matthew W. Martinez Md, Tanujit Dey Phd

Department of Medicine

No abstract provided.

Assessing Vancouver After Facts, Accusations, Shades Of Truth, Rick Burton, Norm O'Relly

Sport Management - All Scholarship

No abstract provided.

Transcriptional Profiles For Glutamate Transporters Reveal Differences Between Organophosphates But Similarities With Unrelated Neurotoxicants, Theodore A. Slotkin, Doug Lobner, Frederic J. Seidler

Biomedical Sciences Faculty Research and Publications

The developmental neurotoxicity of organophosphates involves mechanisms other than their shared property as cholinesterase inhibitors, among which are excitotoxicity and oxidative stress. We used PC12 cells as a neurodevelopmental model to compare the effects of chlorpyrifos and diazinon on the expression of genes encoding glutamate transporters. Chlorpyrifos had a greater effect in cells undergoing nerve growth factor-induced neurodifferentiation as compared to undifferentiated PC12 cells, with peak sensitivity at the initiation of differentiation, reflecting a global upregulation of all the glutamate transporter genes expressed in this cell line. In differentiating cells, chlorpyrifos had a significantly greater effect than did diazinon and …

Medical School Watercooler Newsletter - August 29, 2010, Lindsey Lyle

Watercooler Newsletter

This is the August 29, 2010 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

• USA Football Program "Sneak Peek"
• Clyde Huggins Recipients Announced at 2010 Medical Student Research Day
• Harry Potter Exhibit Begins Next Week at USA Biomedical Library
• USA Women in Science Organization Hosts GEMS --Girls Exploring Math and Science
• Med School Café - Expert Advice For The Community
• USA Knollwood Physicians Group Welcomes Dr. Christi Cazalas

Today - August 27, 2010, Loma Linda University

TODAY

Inside this issue:

-- $2.1 million NIH grant will enable pharmacy professor to study HIV/AIDS prevention
-- Loma Linda University Medical Center sweeps its categories at Pacific Southwest Emmy Awards
-- The future of parking at LLU
-- Researchers at Loma Linda University School of Medicine and George Mason University find promising biomarker source in early detection of Alzheimer's
-- BMC administrator speaks out on the stigma of mental illness
-- LLU Medical Center boasts largest hyperbaric oxygen chamber on West Coast
-- Phil-Anne Krogman leaves the door open as she says farewell to FMO
-- Loma Linda University operators …

Plasticity Of Brain Networks In A Randomized Intervention Trial Of Exercise Training In Older Adults, Michelle W. Voss, Ruchika S. Prakash, Kirk I. Erickson, Chandramallika Basak, Laura Chaddock, Jennifer S. Kim, Heloisa Alves, Susie Heo, Amanda N. Szabo, Siobhan M. White, Thomas R. Wójcicki, Emily L. Mailey, Neha Gothe, Erin A. Olson, Edward Mcauley, Arthur F. Kramer

Kinesiology, Health and Sport Studies

Research has shown the human brain is organized into separable functional networks during rest and varied states of cognition, and that aging is associated with specific network dysfunctions. The present study used functional magnetic resonance imaging (fMRI) to examine low-frequency (0.008 < f < 0.08 Hz) coherence of cognitively relevant and sensory brain networks in older adults who participated in a 1-year intervention trial, comparing the effects of aerobic and nonaerobic fitness training on brain function and cognition. Results showed that aerobic training improved the aging brain’s resting functional efficiency in higher-level cognitive networks. One year of walking increased functional connectivity between aspects of the frontal, posterior, and temporal cortices within the Default Mode Network and a Frontal Executive Network, two brain networks central to brain dysfunction in aging. Length of training was also an important factor. Effects in favor of the walking group were observed only after 12 months of training, compared to non-significant trends after 6 months. A non-aerobic stretching and toning group also showed increased functional connectivity in the DMN after 6 months and in a Frontal Parietal Network after 12 months, possibly reflecting experience-dependent plasticity. Finally, we found that changes in functional connectivity were behaviorally relevant. Increased functional connectivity was associated with greater improvement in executive function. Therefore the study provides the first evidence for exercise-induced functional plasticity in large-scale brain systems in the aging brain, using functional connectivity techniques, and offers new insight into the role of aerobic fitness in attenuating age-related brain dysfunction.