Medicine and Health Sciences Commons^™

On The Utility Of Stochastic Models Of Chronic Obstructive Pulmonary Disease, Rebecca Boehm

MUSC Theses and Dissertations

Chronic obstructive pulmonary disease (COPD) is a progressive and irreversible lung disease characterized by reduced lung function, abnormal inflammatory response, dyspnea, increased sputum production, and costly and debilitating exacerbations. Common treatments for COPD include smoking cessation therapy, short- and long-acting bronchodilators, inhaled corticosteroids, pulmonary rehabilitation, and home oxygen therapy. However, a recent meta-analysis demonstrated that inhaled corticosteroids fail to slow the decline in FEV1, the primary clinical marker of COPD progression. In addition, some evidence exists to suggest that long-term inhaled corticosteroid use may increase bone density loss, leading to osteoporosis. Given that the bone health effects of inhaled corticosteroid …

Non-Traumatic Aortic Emergencies - Experience From A Tertiary Care Centre In, Nadeem Khan Ullah Khan, Junaid A. Razzak, Hasanat Sharif, Saqib Hamid Qazi

Department of Emergency Medicine

Objective: To review the incidence, clinical presentation and outcome of Non traumatic Aortic emergencies in a tertiary care hospital and its evaluation in the Emergency department (ED).
Methods: We conducted a retrospective review of cases presented to the ED at Aga Khan University Hospital during 15 year period (1988 - 2002) who had final diagnosis of Aortic Dissection or Ruptured Aortic Aneurysm. Patients without confirmatory investigations were excluded. We aimed at looking for the incidence, clinical presentation, evaluation in the ED and final outcome.
Results: Of the 12 cases, 7 had aortic dissection while the remaining 5 had ruptured aortic …

Disaster Drill At A University Hospital, Rifat Rehmani

Department of Emergency Medicine

The course of a disaster drill held on 23 October 2001 at Aga Khan University, Karachi is reported. The Hospital Emergency Plan was put to trial on that day. Volunteers were invited to become simulated casualties in the drill. Briefing seminars had been conducted with the key players of the hospital. The scenario was a man-made type disaster. A 747 jumbo jet with 200 passengers had crashed at the end of the runway at Quaid-e-Azam International Airport while taking off in a thunderstorm. Fifty casualties were sent to Emergency Room by ambulance. The Plan was activated and relevant units were …

Graduate Public Health Education In Africa: An Innovative Distance-Learning Model, Emmanuel Rudatsikira, Patricia Johnston, Richard Hart

International Journal of Global Health and Health Disparities

This article describes the development and implementation of a distance graduate public health education program in Africa by Loma Linda University, Loma Linda, California, U.S.A. The program started in March 2000 and ended in September 2003 with formal teaching sessions on-site held twice a year at the University of Eastern Africa, Kenya. The instruction was given in English and French. Of the cohort of 67 students from 20 African countries who started the program, 57 received an M.P.H. degree and six received a certificate in public health. The experiential learning model allowed students to immediately put into practice what they …

Latinas And Breast Cancer In The Midwest: Factors Influencing Survivorship, M. Elise Radina, Daniel R. Longo, Jane M. Armer

International Journal of Global Health and Health Disparities

Latinos are the largest ethnic minority group in the U.S. and the Midwest is experiencing the fastest growth in residents of Hispanic descent. Rural health care delivery systems in these areas must therefore respond to changing demographics and provide culturally appropriate service delivery. The incidence rate of breast cancer among Latinas is lower than that among non-Hispanic women; however an increasing number of Latinas are being diagnosed with breast cancer. Despite higher mortality rates from cancer than non-Hispanic women, more Latinas are being treated for breast cancer and are now facing their own unique survivorship experiences This paper addresses factors …

The Role Of The Insecticide Ddt In Breast Cancer, Jared D. Taylor

International Journal of Global Health and Health Disparities

Breast cancer is by far the most common cancer among black and white females, with approximately 211,000 new cases expected to be diagnosed in the U.S. in 2004 (1). More importantly, incidence has been increasing. Age-adjusted breast cancer incidence in U.S. females rose from the 88.6 per 100,000 in the early 1970s to 109.8 in the early 1990s (2). This represents a 24 percent increase over that time. This trend is only partially explained by the known risk factors for breast cancer, including advancing age, early menarche, late menopause, late age at first parturition and family history. Therefore, researchers have …

Socioeconomic Status And Tobacco Use, Jennifer Cook

International Journal of Global Health and Health Disparities

Cigarette smoking remains the leading cause of illness, disability and death in the United States, and more than 400,000 premature deaths occur each year in this country from tobacco-related causes (1). More than 80 percent of adult smokers first become regular smokers by the age of 18, and casual experimentation with smoking by adolescents frequently develops into regular smoking and a strong addiction. Despite the growth in anti-tobacco campaigns, research has shown that socioeconomic status (SES) is still a major determinant as to whether or not teens begin smoking (2). A recent analysis of data from the 2000 National Health …

Bush's Gag Rule And Africa: Impact On Reproductive Health, John Kemoli Sagala

International Journal of Global Health and Health Disparities

Throughout most of the 20th century, multilateral development partnership in the area of reproductive health was one of the few success stories in public health. Globally, by 1998, 58 percent of all married women had access to modern contraceptives and other family planning services. This represented 67 percent of married women in developed countries and 54 percent in developing countries. Since taking office in 2001, President George W. Bush has sought to undo these achievements through the global gag rule. On January 20, 2001, President Bush reinstated the 1984 Reagan Mexico City Policy or global gag rule. The global gag …

Information For Authors

International Journal of Global Health and Health Disparities

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Programming For Hiv Prevention In South African Schools: A Report On Program Implementation, Priscilla Reddy, Shegs James, Ann P. Mccauley

HIV and AIDS

An evaluation study conducted in KwaZulu Natal, South Africa, provides important insights into whether learners who participated in a fact-based, interactive course had more knowledge about HIV risks, prevention, and care practices; more positive attitudes toward prevention practices and people living with HIV and AIDS; and a higher prevalence of reported safe behaviors than comparable learners who did not participate in the course. Results show that the Life Skills Grade 9 Curriculum had a positive impact of students’ knowledge of HIV/AIDS, attitudes about abstinence, and intention to use condoms. There was, however, no evidence of increased adoption of such protective …

Synthesis Of Intermediates Of Receptor-Subtype Selective Lpa Antagonists, Danielle Zafrane

Theses & Honors Papers

It has been shown that 1-oleoyl lysophosphatid ic acid (LPA; 1-acyl-2-glycerol-3-phosphate) plays a vital role in the progression and proliferation of ovarian cancer. The design and synthesis of LPA receptor selective agonists and antagonists has been the focus of intense research within the last ten years .¹ During the Research Experience for Undergraduate s (REU) internship at the University of Virginia 4-bromo-2-(hydroxymethyl)pyridine (intermediate 43) was designed and synthesized based on earlier results. Intermediate 43 was used to modify a current LPA analogue. Modification of current LPA analogues may result in the discovery of potent and metabolically stable LPA antagonists …

Law, Medicine, And Religion: Towards A Dialogue And A Partnership In Biomedical Technology And Decision Making, George P. Smith Ii

Scholarly Articles

Faith, religion, spirituality, and prayer have a current focused outreach and easy parlance in the market places and public squares of the nation. News stories and court cases abound with dramatic challenges to the placement of monuments to the Ten Commandments in public buildings and grounds, the use of God's name in school pledges of allegiance, the teaching of Darwinian or evolutionary science in public education, the role of faith and religion in health care healing, and even the value of affirmations of religious faith on the political hustings. The purpose of this article is to explore the conjunctive and …

The Public's Perception And Satisfaction With Physician Assistants Serving In Southeast San Bernardino County, Liana Pena, Hoshang Irani, Reginald Peters

Loma Linda University Research Reports

Purpose: The physician assistant profession is relatively new and continues to have an increasing demand in health care. Physician assistants (P As) have become a great asset to the medical field. The purpose of the study was to investigate the public's view of the roles played by PAs in patients' care, and its level of satisfaction and comfort with the quality of care P As provide in an urban setting. Methods: We used a survey that was written in two languages (English and Spanish) to assess satisfaction and comfort levels of 140 subjects, 18-80 years of age, in two primary …

A Comparison Of The Effects On Throwing Velocity Of Straight Plane Versus Diagonal Plane Shoulder Exercises On 18-30 Year Old Non-Athletes, Jason Allred, Kevin O'Brien, Peter Tran

Physical Therapy Scholarly Projects

The purpose of this study was to examine changes in throwing velocity exhibited by subjects placed in a straight-line resistance-training group, a proprioceptive neuromuscular facilitation (PNF) resistance-training group, and a control group in order to compare benefits between training programs. Subjects were comprised of 42 college students between the ages of 18 and 30. The subjects were placed in one of the three experimental groups (straight-line resistance-training, PNF resistance training, and control) using Theraband™ elastic tubing. Each subject's overhand throwing velocity was measured on two separate occasions separated by 8-weeks of training. Rate of perceived exertion (RPE) was used to …

Survey Of The Use Of Pedometers And Knowledge Of Caloric Intake And Expenditure, Tera Bahl, Holly Freudenberg, Tara Hynek, Lynae Jost

Physical Therapy Scholarly Projects

Background and Purpose. As the prevalence of obesity continues to rise, medical professionals are searching for ways to combat this epidemic. One of the first steps is to assess the activity levels and eating habits of those who are obese and look for ways to modify these two areas in order to assist the obese individual in achieving a desirable and healthy weight. The purpose of this study is to determine if pedometer use, gender, or body mass influence one's knowledge of caloric consumption and expenditure.

Subjects and Methods. 253 questionnaires were sent out to randomly selected faculty and staff …

Effects Of Ankle Taping On Postural Stability, Jessica Brown, Andrea Foley, Michelle Hager, Andrea Kresel

Physical Therapy Scholarly Projects

Ankle taping is a common practice used to support the ankle joint after injury when engaging in activities. Balance is a crucial component of athletic performance that relies on input from the vestibular, somatosensory, and visual systems. Proprioception plays a role in the somatosensory portion of balance and postural control. Ankle taping, which is used to improve performance, may alter a person's proprioception, balance, and postural control.

The purpose of this study is to determine if ankle taping has an effect on postural control in an individual free of chronic or acute ankle dysfunction. Thirty-two subjects were tested on a …

Factors That Influence The Utilization Of Fitness/Recreation Facilities By Individuals With Physical Disabilities, Brenda Finley, Kristen Lindstrom, Jennifer Lorengo, Brandi Muir

Physical Therapy Scholarly Projects

This research project was designed to provide well ness/fitness facilities, particularly the upcoming Wellness Center at the University of North Dakota (UND), with useful information to make facilities more accommodating to all individuals. The purpose of this study was to investigate the factors that influence participation in physical activity among people with physical disabilities and to investigate the types of accommodations and modifications that fitness facilities have in place.

Six individuals with physical disabilities participated in the focused interview portion of this study. Participants suggested modifications concerning physical activity for staffing, additional equipment, and other specific adaptations. The majority of …

An Evaluation Of The Ability Of Physical Therapy Students At The University Of North Dakota To Make Ethical Decisions, Russell B. Fox

Physical Therapy Scholarly Projects

Physical therapists are faced with many ethical dilemmas in the work place. Therefore, it is important for a physical therapy student to have the ability to make sound ethical decisions. However, there are no classes required by the physical therapy department in ethics at the University of North Dakota. The purpose of this study is to examine the ability of physical therapy students and the faculty at the University of North Dakota to make ethical decisions.

During the summer of 2004, the Defining Issues Test II (DIT-2) was administered at the University of North Dakota. The DIT-2 is a structured …

The Effectiveness Of Partial Body Weight Support Treadmill Training On Muscle Activation And Gait With Normal Subjects, Malanie A. Hanson, Cherron M. Kingzett, Amanda M. Klempel, Jenny M. Silbernagel

Physical Therapy Scholarly Projects

Background and Purpose: The purpose of this study was to evaluate gait kinematics of individuals without pathological impairments. Through the use of electromyography (EMG), the firing of muscles was analyzed during ambulation using the partial body weight support treadmill training (PBWSTT). Video motion analysis (VMA) was also used to look at the movements of the lower extremities and the pelvis. Using both of these tools, it was determined if there was a significant change in muscle firing and movements in normal individuals during ambulation with weight support compared to normal weight-bearing.

Methods: Four subjects (3 female, 1 male) were recruited …

An Electromyography (Emg) Study Of Two Dynamic Surfaces: Hippotherapy And Swiss Ball, Melissa J. Metcalf, Roslyn J. Muller, Tanya L. Schimek, Erica H. Wheeler

Physical Therapy Scholarly Projects

The use of horseback riding as a therapeutic intervention has been used since the fifth century, B.C.1 It has been proposed that the physical benefits of horseback riding include: improved posture, balance, muscle strength, decreased spasticity, improved gait patterns, and coordination. Unfortunately, at the current time, hippotherapy, the use of horses in physical therapy intervention, has been poorly documented due to little objective research. The purpose of this study was to provide an objective measure of children's postural muscle activity through the use of electromyography (EMG) and electrogoniometry on two dynamic surfaces. Data was analyzed for differences in postural muscle …

Overcoming Barriers In Fitness Equipment For Persons With Physical Disabilities, Collin Wiggins, Thomas Carson, Aaron Sorvig

Physical Therapy Scholarly Projects

Americans today are generally inactive, and the incidence of physical inactivity is even higher among those with disabilities. Many advances have been made in recreational sports facilities; however, insufficient information regarding equipment selection or equipment design remains, and thus may limit the active participation of the physically disabled at most colleges/universities. The purpose of this study was to determine guidelines for identifying types of equipment, accommodations, and funding sources available to provide those with physical disabilities an adequate and equal means of improving their fitness level.

Facilities chosen to participate in this study are registered college/university recreation centers with the …

Ic079: Headlines Newsletter, Vol. 8, No. 1, January-April 2005; Muse News Newsletter, Summer & Fall 2005, John P. Mcgovern Museum Of Health And Medical Science

Museum Publications (1998-2009)

McGovern Museum of Health and Medical Science January-April 2005 bulletin, Summer 2005, Fall 2005 featuring news and information on upcoming museum events, exhibits, and program. Also includes Invitation to Tailgate Party given by John P. McGovern Museum of Health and Science.

Narratives Of Adolescent Students: The Integration Of Health And Learning Through Application Of Nursing Theory, Marjean Huber

Dissertations

Problem. There are few resources to show educators how to help students improve learning by improving health and mental well-being. There is a lack of integration in the literature in terms of how practitioners can reach these students in order to help them learn effectively and develop into successful, productive adults with meaningful lives. This study has three major sections. First, I examine my experiences within education to determine what values, truths, and principles mold my practice. Second, I identify my teaching practice in relationship to nursing theory integrating it with learning theory, thus highlighting the relationship between the health …

Demographic Characteristics And Academic Measures As Predictors Of Success On The American Society For Clinical Pathology (Ascp) Medical Technologist Certification Examination, Marcia Ann Kilsby

Dissertations

Purpose. This study was undertaken to address the utility of demographic characteristics and academic measures as predictors of success for the American Society for Clinical Pathology Board of Registry Medical Technologist Certification Examination (Certification Examination) Total Score and six Subscores and to find predictive models with relevance to an ethnically and racially-diverse student population.

Method. The research population was the graduates of the Andrews University Program for Clinical Laboratory Sciences. The 233 subjects were from 53 different birth countries. The relationships between Certification Examination scores and both demographic characteristics and academic measures were analyzed by chi square, analysis o f …

Stability Study Of Phoslactomycin B And Analysis Of Degradation Products, Choudhuri Suparna Das

Theses and Dissertations

Phoslactomycin B (PLM-B), a potent and selective inhibitor of serine threonine phosphatase is of interest for its antitumor, antifungal and antiviral activity. The objective of this study was to evaluate the stability of phoslactomycin B at various pH and temperature conditions. Phoslactomycin B was produced from the mutant strain NP1 of Streptomyces sp.HK-803 and was purified by semi-preparative HPLC . A study of PLM-B degradation was carried out in the pH range of 2-10 at 30ºC and 50°C using HPLC. The PLM-B decomposition was observed to exhibit a U-shaped pH profile and demonstrated both acid and base-catalyzed decomposition. The decomposition …

A Descriptive Study Of Ethical Procedures That Maintain Cultural Security When Conducting Health Research With Aboriginal And Torres Strait Islander School Children In Western Australia, Dionne Paki

Theses : Honours

Cultural security is the maintenance of values and beliefs and the celebration of diversity unique to different cultures. This honours thesis developed a proposed framework to guide collaborative ethics procedures that demonstrate the Aboriginal values relevant to health research for use in Western Australia (WA). These values of reciprocity, respect, equality, responsibility, survival and protection, and spirit and integrity have been identified in the National Health and Medical Research Council's Values and Ethics: Guidelines for Ethical Conduct in Aboriginal and Torres Strait Islander Health Research. Ethical procedures for maintaining cultural security when conducting health research among Aboriginal people throughout Australia …

Mfit Weight Management Program: Effects On Anthropometric And Cardiovascular Measures, Lindsay L. Boik

Senior Honors Theses and Projects

Objective: Traditional approaches to address obesity typically entail severe caloric restriction and drastic alterations in activity pattern. The MFit Weight Management Program, a derivative of the University of Michigan Health System, takes a different approach to weight loss. The goal of the program is to stress the development of longterm lifestyle changes and it places less emphasis on rapid weight loss. It was the purpose of this study to determine whether the MFit Weight Management Program, a behavioral modification program, is successful for decreasing anthropometric and cardiovascular measurements of obesity. Research Methods and Procedures: This is an ongoing study with …

Beyond The Pavement: How To Take On Cross-Country Mountain Biking, Gregory M. Moore

Senior Honors Theses and Projects

Mountain biking began for me as an escape from the commotion of urban society. I was looking for a way to get out of life’s normal grind and take advantage of my love for being active and outside. Mountain biking was the perfect sport to meet my desires. I have become an advocate for mountain biking early on. I am now taking this opportunity to teach people about the sport I have come to love.

The objectives of this book are two fold. Part I serves as a comprehensive guide to cross-country mountain biking that will provide new comers with …

Mouse Cytomegalovirus M33 Is Necessary And Sufficient In Virus-Induced Vascular Smooth Muscle Cell Migration, Ryan Melnychuk, Patsy Smith, Craig N. Kreklywich, Franziska Ruchti, Jennifer Totonchy, Laurel Hall, Lambert Loh, Jay A. Nelson, Susan L. Orloff, Daniel N. Streblow

Pharmacy Faculty Articles and Research

Mouse cytomegalovirus (MCMV) encodes two potential seven-transmembrane-spanning proteins with homologies to cellular chemokine receptors, M33 and M78. While these virus-encoded chemokine receptors are necessary for the in vivo pathogenesis of MCMV, the function of these proteins is unknown. Since vascular smooth muscle cell (SMC) migration is of critical importance for the development of atherosclerosis and other vascular diseases, the ability of M33 to promote SMC motility was assessed. Similar to human CMV, MCMV induced the migration of mouse aortic SMCs but not mouse fibroblasts. To demonstrate whether M33 was required for MCMV-induced SMC migration, we employed interfering-RNA technology to specifically …

Saddle Height Positioning For Triathletes Ssing Road Cyclist Methods, Edith Ann Sherman

Master's Theses and Doctoral Dissertations

Triathlon is the combined sport of swimming, cycling, and running. Cycling is normally the longest portion of the race. Therefore, maintenance of comfort and efficiency while maintaining high power output is essential for success in the cycling portion. Several methods are currently used for determination of height for road cyclists. It has yet to be determined if these methods are applicable to triathletes. Because of the different geometry of a triathlon bicycle, the question remains whether road-saddle fitting techniques can be an applied and work for the triathlon bicycle.

This thesis evaluated the participant’s current saddle height in addition to …