Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Public Health (787)
- Life Sciences (366)
- Veterinary Medicine (304)
- Medical Specialties (293)
- Psychiatry and Psychology (233)
-
- Social and Behavioral Sciences (233)
- Animal Sciences (218)
- Medical Sciences (213)
- Other Psychiatry and Psychology (148)
- Dentistry (134)
- Nursing (127)
- Rehabilitation and Therapy (117)
- Arts and Humanities (103)
- Diseases (93)
- Physical Sciences and Mathematics (80)
- Sociology (74)
- Education (73)
- Mental and Social Health (68)
- History (67)
- Law (67)
- Psychology (63)
- Pharmacy and Pharmaceutical Sciences (57)
- Occupational Health and Industrial Hygiene (53)
- Business (50)
- History of Science, Technology, and Medicine (50)
- Health Law and Policy (43)
- International Public Health (43)
- Epidemiology (42)
- Health and Medical Administration (42)
- Institution
-
- Thomas Jefferson University (493)
- TÜBİTAK (276)
- Wright State University (165)
- Chulalongkorn University (144)
- University of Nebraska - Lincoln (115)
-
- Aga Khan University (112)
- Washington University School of Medicine (99)
- Loma Linda University (68)
- Virginia Commonwealth University (62)
- Nova Southeastern University (53)
- University of North Dakota (48)
- University of Kentucky (47)
- University of Northern Iowa (38)
- Institut de Recherche Robert-Sauvé en santé et en sécurité du travail (37)
- Population Council (37)
- Old Dominion University (35)
- American Dental Association (34)
- Dartmouth College (33)
- Marquette University (33)
- Taiwan Academy of Physical Medicine and Rehabilitation (33)
- University of San Diego (30)
- University of the Pacific (30)
- Himmelfarb Health Sciences Library, The George Washington University (27)
- Brigham Young University (26)
- Edith Cowan University (25)
- COBRA (23)
- University of North Florida (23)
- Western Kentucky University (22)
- Western University (21)
- Marshall University (20)
- Keyword
-
- Humans (57)
- Animals (42)
- Continuing medical education (34)
- English (34)
- CME (32)
-
- Newsletter (30)
- Female (27)
- Medical education (26)
- Male (25)
- Newspaper (25)
- Oral health (24)
- Nursing (23)
- Broadsheet (22)
- Mice (22)
- Paper (22)
- Professional association (22)
- Genetics (19)
- Health policy (19)
- Public health (19)
- Québec (19)
- Women (19)
- Huntington's Disease (17)
- Dentistry (16)
- Dog (16)
- Aged (15)
- Medicare (15)
- Metabolism (15)
- Quality of health care (15)
- Rehabilitation (15)
- Treatment (15)
- Publication
-
- Population Health Matters (Formerly Health Policy Newsletter) (436)
- Turkish Journal of Veterinary & Animal Sciences (206)
- International Symposium on Aviation Psychology - 2005 (144)
- Turkish Journal of Medical Sciences (70)
- Theses and Dissertations (67)
-
- Chulalongkorn Medical Journal (63)
- Open Access Publications (60)
- Department of Psychology: Faculty Publications (48)
- Loma Linda University Electronic Theses, Dissertations & Projects (45)
- The Thai Journal of Veterinary Medicine (43)
- Rapports de recherche scientifique (37)
- Faculty Publications (35)
- Dartmouth Scholarship (33)
- Rehabilitation Practice and Science (33)
- Occupational Therapy Capstones (29)
- Chulalongkorn University Dental Journal (28)
- Internet Journal of Allied Health Sciences and Practice (28)
- Department of Pathology and Laboratory Medicine (24)
- School of Pharmacy Faculty Articles (24)
- ADA News (22)
- Florida Public Health Review (22)
- International Journal of Global Health and Health Disparities (20)
- Dissertations (19)
- Master's Projects (18)
- Theses Digitization Project (18)
- At Risk for Huntington's Disease (17)
- Posters (17)
- Reproductive Health (17)
- All-Inclusive List of Electronic Theses and Dissertations (16)
- College of Nursing Faculty Research and Publications (16)
- Publication Type
- File Type
Articles 1471 - 1500 of 2796
Full-Text Articles in Medicine and Health Sciences
Fas Ligand Expression In The Porcine Oviduct, Paisan Tienthai, Yumi Hoshino
Fas Ligand Expression In The Porcine Oviduct, Paisan Tienthai, Yumi Hoshino
The Thai Journal of Veterinary Medicine
The expression of Fas/Fas Ligand (FasL) is thought to be involved in the immune privileged status of the testis, cornea and the placenta. The objective of this study was to see whether FasL mRNA was expressed in the epithelium of the porcine oviduct, where spermatozoa, oocytes and developing embryos avoid elimination by the female immune system during the estrous cycle. The distribution of Fas/FasL might provide information about immune privileged sites in the pig oviduct. The gene expression of FasL was detected in the uterotubal junction (UTJ), isthmus and ampulla of the pig oviductal epithelium, during both pre- and post-ovulatory …
The Characterization Of The 18s Rrna Gene Using A Pcr-Rflp In Order To Develop A Differential Diagnostic Tool For Avian Eimeria Spp., Silamon Choosaksangthong, Woraporn Sukhumavas, Sudjit Chungpivat, Nareerat Viseshakul
The Characterization Of The 18s Rrna Gene Using A Pcr-Rflp In Order To Develop A Differential Diagnostic Tool For Avian Eimeria Spp., Silamon Choosaksangthong, Woraporn Sukhumavas, Sudjit Chungpivat, Nareerat Viseshakul
The Thai Journal of Veterinary Medicine
Avian coccidiosis is a protozoan disease which can be caused by at least 7 species of the genus Eimeria. Species of Eimeria in chicken are distinguished by their distinct morphology and where sites the parasotes are deposited in the small intestine of the infected birds. The criteria for Eimeria species differentiation when the disease occures is sometimes unreliable. Based on 422 base pairs derived from the 3 prime-region of the 18S rRNA gene, containing polymorphic DNA sequences of Eimeria, the technique of PCR-RFLP (Polymerase chain reaction and Restriction fragment length polymorphisms) has been developed to identify species-specific DNA profiles of …
Epistasis Among Presynaptic Serotonergic System Components, Scott F. Stoltenberg
Epistasis Among Presynaptic Serotonergic System Components, Scott F. Stoltenberg
Department of Psychology: Faculty Publications
Epistatic interactions among regulatory components of the serotonin (5-HT) neurotransmitter system may be an important aspect of 5-HT function. Because 5-HT dysregulation is associated with several common psychiatric disorders, the potential for epistasis among genetic variants in the 5-HT transporter (SERT), 5-HT1B terminal autoreceptor and the 5- HT1A somatodendritic autoreceptor should be examined. In this study, output from a dynamic minimal model of 5-HT function was compared to empirical results in the literature. Parameters representing extracellular 5-HT clearance rates (SERT), 5-HT release levels (5-HT1B) and inhibitory thresholds (the amount of extracellular 5-HT above which cell firing …
Promoting Healthful Diets And Exercise: Efficacy Of A 12-Week After-School Program In Urban African Americans, Hermann-J. Engels, Randall J. Gretebeck, Kimberlee A. Gretebeck, Linda Jimenez
Promoting Healthful Diets And Exercise: Efficacy Of A 12-Week After-School Program In Urban African Americans, Hermann-J. Engels, Randall J. Gretebeck, Kimberlee A. Gretebeck, Linda Jimenez
College of Nursing Faculty Research and Publications
This study examined the effectiveness of a unique extracurricular after-school initiative designed to promote healthy diets and exercise in urban African Americans. The Students and Parents Actively Involved in Being Fit after-school program was offered for 12 weeks to students and their parents/guardians at an urban middle school. Specific aims of the intervention were to increase participants’ vegetable and fruit intake by using established 5 A Day for Better Health educational resource materials/activities and to affect their health-related fitness through dance, games, and fitness activities. Fifty-six children and 25 parents/guardians completed a standard battery of evaluations before and after the …
Determinants Of Physical Activity And Low-Fat Diet Among Low Income African American And Hispanic Middle School Students, Marilyn Frenn, Shelly Malin, Antonia M. Villarruel, Kimberly Slaikeu, Stephanie Mccarthy, Joan Freeman, Erinn Nee
Determinants Of Physical Activity And Low-Fat Diet Among Low Income African American And Hispanic Middle School Students, Marilyn Frenn, Shelly Malin, Antonia M. Villarruel, Kimberly Slaikeu, Stephanie Mccarthy, Joan Freeman, Erinn Nee
College of Nursing Faculty Research and Publications
African Americans, Hispanics, and those with low income experience disproportionate health problems that can be prevented by physical activity and a lower fat diet. In this descriptive cross-sectional study, antecedents of diet and exercise within the Health Promotion/Transtheoretical Model were examined among low-income African American and Hispanic seventh-grade students (n = 127). Total support was associated with higher physical activity for girls. African Americans perceived greater social support for activity than Hispanics. Family models and support for physical activity and low-fat diet were greater as family income increased. However, higher family role models and lower dietary fat were found …
Viagra: Medical Technology Constructing Aging Masculinity, Gregory Gross, Robert Blundo
Viagra: Medical Technology Constructing Aging Masculinity, Gregory Gross, Robert Blundo
The Journal of Sociology & Social Welfare
Medicalization and commodification of the body through technology in the form of Viagra and other erectile dysfunction drugs is reinforcing the cultural expectations that ageing men are required to age well to maintain youthful masculinity. Ageing well is explored as it relates the construction of masculinity, sexuality and ageing men's bodies.
Inside Unlv, Erin O'Donnell, Carol C. Harter, Cate Weeks, Nancy Syzdek
Inside Unlv, Erin O'Donnell, Carol C. Harter, Cate Weeks, Nancy Syzdek
Inside UNLV
No abstract provided.
An Analysis Of Biometric Technology As An Enabler To Information Assurance, Darren A. Deschaine
An Analysis Of Biometric Technology As An Enabler To Information Assurance, Darren A. Deschaine
Theses and Dissertations
The use of and dependence on, Information technology (IT) has grown tremendously in the last two decades. Still, some believe the United States is only in the infancy of this growth. This explosive growth has opened the door to capabilities that were only dreamed of in the past. As easy as it is to see how advantageous this technology is, it also is clear that with its advantages come distinct responsibilities and new problems that must be addressed. For instance, the minute one begins using information processing systems, the world of information assurance (IA) becomes far more complex. As a …
Rat/Mgra, A Regulator Of Autolysis, Is A Regulator Of Virulence Genes In Staphylococcus Aureus, Susham Ingavale, Willem Van Wamel, Thanh T. Luong, Chia Y. Lee, Ambrose L. Cheung
Rat/Mgra, A Regulator Of Autolysis, Is A Regulator Of Virulence Genes In Staphylococcus Aureus, Susham Ingavale, Willem Van Wamel, Thanh T. Luong, Chia Y. Lee, Ambrose L. Cheung
Dartmouth Scholarship
We have previously identified mgrA (rat) as a regulator of autolysis in Staphylococcus aureus. Besides its effect on autolytic activity, we recently found alterations in the expression of regulator and target virulence genes in the mgrA mutant. Northern analysis and transcription fusion assays showed that inactivation of mgrA has led to the downregulation of RNAIII of agr and hla and upregulation of sarS and spa. Although both SarA and agr are activators of α-hemolysin and a repressors of protein A synthesis, we found that the transcription of sarA was not affected in the mgrA mutant and …
Principles Of Clinical Practice With Older Men, Lenard W. Kaye, Jennifer A. Crittenden
Principles Of Clinical Practice With Older Men, Lenard W. Kaye, Jennifer A. Crittenden
The Journal of Sociology & Social Welfare
Older men are much less likely to be aware of community services available to them and they are less likely to utilize services generally. This underutilization is affected by the way in which social services are organized and how practitioners function within them. Since there are greater numbers of elderly women and women utilize services more readily, practice tends to be female-centered. It is important that gender-sensitive intervention processes are established that recognize the unique experiences and concerns of older men in order to better serve them. The uniqueness of men's experiences with such issues as loss of a spouse, …
Olfactory Neuroblastoma: A Case Report And Review Of The Literature, Shehzad Ghaffar, Iftikhar Salahuddin
Olfactory Neuroblastoma: A Case Report And Review Of The Literature, Shehzad Ghaffar, Iftikhar Salahuddin
Section of Otolaryngology, Head & Neck Surgery
Malignant tumors of the nasal cavity are rare. We report the case of an elderly woman who consulted us with a 4-year history of progressive nasal obstruction, occasional epistaxis, facial pain, and watering of the eyes. A diagnosis of olfactory neuroblastoma was established by histopathology and confirmed by immunohistochemistry. On staging, the mass was classified as a Kadish stage B tumor. The mass was excised via a lateral rhinotomy approach, and the tumor was peeled away completely from the cribriform plate with endoscopes. The patient underwent postoperative radiation, and she was free of recurrence at follow-up 15 months later.
Hyaluronan In The Sow’S Oviduct: Its Effect On Boar Sperm Morphology And Function, Paisan Tienthai
Hyaluronan In The Sow’S Oviduct: Its Effect On Boar Sperm Morphology And Function, Paisan Tienthai
The Thai Journal of Veterinary Medicine
During sperm transport in the female pig, a proportion of the spermatozoa is arrested at the uterotubal junction and the isthmus, where an oviductal sperm reservoir is built up. The sperm reservoir maintains sperm viability and controls the release of fertilizing spermatozoa so that only a small subpopulation reaches the site of fertilization, thus diminishing the risk of polyspermy. In vitro research has focused on sperm binding as the main mechanism of sperm storage, sperm release and modulation of capacitation, but little attention has been paid to the sperm reservoir fluid, its composition and the control of capacitation in vivo. …
The Effect Of Culture Media And Culture Time On The In Vitro Maturation Of Domestic Cat Oocytes, Ruttachuk Rungsiwiwut, Ampika Thongphagdee, Pranee Numchaisrika, Sudsan Sirivaidayapong, Mongkol Techakumphu
The Effect Of Culture Media And Culture Time On The In Vitro Maturation Of Domestic Cat Oocytes, Ruttachuk Rungsiwiwut, Ampika Thongphagdee, Pranee Numchaisrika, Sudsan Sirivaidayapong, Mongkol Techakumphu
The Thai Journal of Veterinary Medicine
Culture media and culture time play important roles in meiotic competence and in vitro development of domestic cats oocytes. This experiment was designed to investigate the effects of culture media (M199 versus DMEM) on the in vitro maturation of domestic cat oocytes, after culturing for 24, 36 and 48 h. Domestic cat ovaries were obtained from routine ovariohysterectomy at an animal hospital, cooled to 4oC and transferred immediately to the laboratory. The oocytes were collected by slicing ovaries in the collecting medium. Five to ten cumulus oocyte complexes (COCs) were cultured in small drops of 50 μl of M199 or …
The Anatomy And Radiography Of The Lungs Of A Stillborn Asian Elephant (Elephas Maximus Indicus), Kriengyot Sajjarengpong, Adisorn Adirekthaworn, Pawana Uthaichotiwan
The Anatomy And Radiography Of The Lungs Of A Stillborn Asian Elephant (Elephas Maximus Indicus), Kriengyot Sajjarengpong, Adisorn Adirekthaworn, Pawana Uthaichotiwan
The Thai Journal of Veterinary Medicine
The lung of a stillborn female Asian elephant (Elephas maximus indicus) was disected for macroscopic anatomical study. It’s tracheobronchial ramifications were studied by a contrast radiographic technique using barium sulphate infusion. The lung was thick and triangular in shape. The right lung was divided into 4 lobes: cranial, middle, caudal and accessory, while the left lung had 3 lobes: cranial, middle and caudal. The lobulation was obvious, but the tracheal bronchus was not found. The cranial lobe of the left and right lungs was divided into cranial and caudal parts. The right, middle and left tracheobronchial lymph nodes were denominated …
Ultrasound Diagnosis, Phiwipha Kamonrat
Ultrasound Diagnosis, Phiwipha Kamonrat
The Thai Journal of Veterinary Medicine
No abstract provided.
What Is Your Diagnosis?, Pranee Tuntivanich, Suwicha Chuthateph
What Is Your Diagnosis?, Pranee Tuntivanich, Suwicha Chuthateph
The Thai Journal of Veterinary Medicine
No abstract provided.
Smoke-Free Laws And Indoor Air Pollution In Lexington And Louisville, Ellen J. Hahn, Kiyoung Lee, Chizimuzo T.C. Okoli, Adewale Troutman, Robert W. Powell
Smoke-Free Laws And Indoor Air Pollution In Lexington And Louisville, Ellen J. Hahn, Kiyoung Lee, Chizimuzo T.C. Okoli, Adewale Troutman, Robert W. Powell
Nursing Faculty Publications
No abstract provided.
Hemorrhagic Corpus Luteum Mimicking Heterotopic Pregnancy, Saba Sohail
Hemorrhagic Corpus Luteum Mimicking Heterotopic Pregnancy, Saba Sohail
Department of Radiology
Hemorrhagic corpus luteum (CL) is clinically known to simulate a number of medical, surgical and gynecologic conditions that cause acute abdomen. One such case is hereby presented that mimicked ectopic pregnancy clinically and heterotopic pregnancy on ultrasound. Laparoscopy was decisive.
A Comparison Of The Immunogenicity Of 5 Newcastle Disease Vaccine Strains Used Against Newcastle Disease Virus In Chickens With No New Castle Disease Antibodies, Jiroj Sasipreeyajan
A Comparison Of The Immunogenicity Of 5 Newcastle Disease Vaccine Strains Used Against Newcastle Disease Virus In Chickens With No New Castle Disease Antibodies, Jiroj Sasipreeyajan
The Thai Journal of Veterinary Medicine
One hundred eighty, male layer-type chickens with no antibodies were divided into 6 groups, 30 birds in each. Each group was vaccinated with a different strain of ND vaccine, La Sota, B1, Ulster, VG/GA and 6/10 for groups 1, 2, 3, 4 and 5, respectively. All vaccinated birds received vaccine when 5-weeks-old, by intranasal inhalation. Birds in group 6 were non-vaccinated controls. All birds were weighed when 5-, 8- and 10-weeks-old. They were challenged when 8-weeks-old with local strain of ND virus. Clinical signs and mortality rates were observed for 3 weeks. Serological responses were determined when 5-, 7-, 8-, …
The Influence Of An Improved Microclimate During Lactation On The Reproductive Performance In Sows In Thailand, Annop Suriyasomboon, Nils Lundeheim, Annop Kunavongkrit, Stig Einarsson
The Influence Of An Improved Microclimate During Lactation On The Reproductive Performance In Sows In Thailand, Annop Suriyasomboon, Nils Lundeheim, Annop Kunavongkrit, Stig Einarsson
The Thai Journal of Veterinary Medicine
The aim of this study was to investigate the reproductive performance of lactating sows in Thailand kept in farrowing housing using an evaporative cooling system (EVAP) in comparison with conventional farrowing system (CONV). The study was based on data from one commercial sow herd, with four farrowing houses (one EVAP and three CONV) with sows of different parities, randomly circulating between these farrowing systems. In the herd, continuous farrowing and cross-fostering was practiced, and the litters were weaned at 18.7 ± 1.3 days of age. The data from 11,000 farrowings (between May 1999 to April 2002) were statistically analysed (ANOVA), …
Ecg Quiz, Chollada Buranakarl, Kris Angkanaporn
Ecg Quiz, Chollada Buranakarl, Kris Angkanaporn
The Thai Journal of Veterinary Medicine
No abstract provided.
A Case Of Non-Resolving Cough And Weight Loss., Omer Ashraf, Ali Bin Sarwar Zubairi, Fawad Aslam, Kashif Ashraf, Suhail Muzaffar
A Case Of Non-Resolving Cough And Weight Loss., Omer Ashraf, Ali Bin Sarwar Zubairi, Fawad Aslam, Kashif Ashraf, Suhail Muzaffar
Department of Medicine
Sarcoidosis is a chronic granulomatous multi-system disease with a clinical picture often mimicking tuberculosis. We present a case of a patient who presented with a clinical picture akin to both of these granulomatous disorders and was started on anti-tuberculous regimen despite the lack of any solid evidence pointing towards tuberculosis. As a result her clinical condition continued to deteriorate for months until finally a bronchoscopic biopsy established her disease process as sarcoidosis. She was then started on systemic corticosteroid therapy for sarcoidosis and during the ensuing period has shown marked improvement in her clinical picture with near normalization of the …
Involvement Of Beta-Chemokines In The Development Of Inflammatory Demyelination., Ileana Banisor, Thomas P Leist, Bernadette Kalman
Involvement Of Beta-Chemokines In The Development Of Inflammatory Demyelination., Ileana Banisor, Thomas P Leist, Bernadette Kalman
Department of Neurology Faculty Papers
The importance of beta-chemokines (or CC chemokine ligands - CCL) in the development of inflammatory lesions in the central nervous system of patients with multiple sclerosis and rodents with experimental allergic encephalomyelitis is strongly supported by descriptive studies and experimental models. Our recent genetic scans in families identified haplotypes in the genes of CCL2, CCL3 and CCL11-CCL8-CCL13 which showed association with multiple sclerosis. Complementing the genetic associations, we also detected a distinct regional expression regulation for CCL2, CCL7 and CCL8 in correlation with chronic inflammation in multiple sclerosis brains. These observations are in consensus with previous studies, and add new …
Research News: 2005, No. 1, University Of Mississippi. School Of Pharmacy
Research News: 2005, No. 1, University Of Mississippi. School Of Pharmacy
Research News: Grants and Publications (2000-2014)
Grants, publications, technology transfer, special announcements
Ada News - 02/21/2005, American Dental Association, Publishing Division
Ada News - 02/21/2005, American Dental Association, Publishing Division
ADA News
Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.
Defective B Cell Responses In The Absence Of Sh2d1a, Massimo Morra, Robert A. Barrington, Ana C. Abadia-Molina, Susumo Okamoto, Aimee Julien, Charles A. Gullo Phd, Anuj Kalsy, Matthew J. Edwards, Gang Chen, Rosanne Spolski, Warren J. Leonard, Brigitte T. Huber, Persephone Borrow, Christine A. Biron A. Biron, Abhay R. Satoskar, Michael C. Carroll, Cox Terhorst
Defective B Cell Responses In The Absence Of Sh2d1a, Massimo Morra, Robert A. Barrington, Ana C. Abadia-Molina, Susumo Okamoto, Aimee Julien, Charles A. Gullo Phd, Anuj Kalsy, Matthew J. Edwards, Gang Chen, Rosanne Spolski, Warren J. Leonard, Brigitte T. Huber, Persephone Borrow, Christine A. Biron A. Biron, Abhay R. Satoskar, Michael C. Carroll, Cox Terhorst
Biochemistry and Microbiology
More than half of patients with X-linked lympho-proliferative disease, which is caused by a defect in the intracellular adapter protein SH2D1A, suffer from an extreme susceptibility to Epstein-Barr virus. One-third of these patients, however, develop dysgammaglobulenemia without an episode of severe mononucleosis. Here we show that in SH2D1A-/- mice, both primary and secondary responses of all Ig subclasses are severely impaired in response to specific antigens. Because germinal centers were absent in SH2D1A-/- mice upon primary immunization, and because SH2D1A was detectable in wt germinal center B cells, we examined whether SH2D1A-/- B cell functions were impaired. Using the adoptive …
Quantitative 1h Magnetic Resonance Spectroscopic Imaging Determines Therapeutic Immunization Efficacy In An Animal Model Of Parkinson's Disease., Michael D. Boska, Travis B. Lewis, Christopher J. Destache, Eric J. Benner, Jay A. Nelson, Mariano Uberti, R. Lee Mosley, Howard Gendelman
Quantitative 1h Magnetic Resonance Spectroscopic Imaging Determines Therapeutic Immunization Efficacy In An Animal Model Of Parkinson's Disease., Michael D. Boska, Travis B. Lewis, Christopher J. Destache, Eric J. Benner, Jay A. Nelson, Mariano Uberti, R. Lee Mosley, Howard Gendelman
Journal Articles: Radiology
Nigrostriatal degeneration, the pathological hallmark of Parkinson's disease (PD), is mirrored by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) intoxication. MPTP-treated animals show the common behavioral, motor, and pathological features of human disease. We demonstrated previously that adoptive transfer of Copaxone (Cop-1) immune cells protected the nigrostriatal dopaminergic pathway in MPTP-intoxicated mice. Herein, we evaluated this protection by quantitative proton magnetic resonance spectroscopic imaging (1H MRSI). 1H MRSI performed in MPTP-treated mice demonstrated that N-acetyl aspartate (NAA) was significantly diminished in the substantia nigra pars compacta (SNpc) and striatum, regions most affected in human disease. When the same regions were coregistered with immunohistochemical stains for …
5-Ht1b Receptor-Mediated Presynaptic Inhibition Of Gaba Release In The Suprachiasmatic Nucleus, Jayne R. Bramley, Patricia J. Sollars, Gary E. Pickard, F. Edward Dudek
5-Ht1b Receptor-Mediated Presynaptic Inhibition Of Gaba Release In The Suprachiasmatic Nucleus, Jayne R. Bramley, Patricia J. Sollars, Gary E. Pickard, F. Edward Dudek
School of Veterinary and Biomedical Sciences: Faculty Publications
The suprachiasmatic nucleus (SCN) receives a dense serotonergic innervation that modulates photic input to the SCN via serotonin 1B (5-HT1B) presynaptic receptors on retinal glutamatergic terminals. However, the majority of 5-HT1B binding sites in the SCN are located on nonretinal terminals and most axonal terminals in the SCN are GABAergic. We therefore tested the hypothesis that 5-HT1B receptors might also be located on SCN GABAergic terminals by examining the effects of the highly selective 5-HT1B receptor agonist CP-93,129 on SCN miniature inhibitory postsynaptic currents (mIPSCs). Whole cell patch-clamp recordings of mIPSCs were obtained from rat …
Nanoscintillation Systems For Aqueous-Based Liquid Scintillation Counting, Russell J. Mumper, Michael Jay
Nanoscintillation Systems For Aqueous-Based Liquid Scintillation Counting, Russell J. Mumper, Michael Jay
Pharmaceutical Sciences Faculty Patents
The present invention relates to the use of nanoscintillation systems, or nanoparticles containing fluor molecules, that can be used to detect an electron-emitting or alpha-particle-emitting radioisotope in the absence of organic-solvents commonly used in organic-based liquid scintillation cocktails. The invention also relates to compositions and use of three oil-in-water microemulsion precursors that can be engineered rapidly, reproducibly, and cost-effectively to produce useful nanoparticles less than 100 nanometers.
To Go – Or Not To Go – Public, Kenneth P. Serbin
To Go – Or Not To Go – Public, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.