Medicine and Health Sciences Commons^™

Hubungan Heart Rate Variability Dengan Global Longitudinal Strain Pada Pasien Diabetes Melitus Tipe 2 Di Puskesmas Jakarta, Dwi Rendra Hadi, Lusiani Rusdi, Tri Juli Edi Tarigan, Arif Mansjoer

Jurnal Penyakit Dalam Indonesia

Introduction. Diabetes mellitus (DM) remains a major global health issue due to its direct consequences and complications, particularly cardiovascular complications. These complications are influenced by autonomic neuropathy, which can be assessed by Heart Rate Variability (HRV). Autonomic dysfunction is thought to impair heart function, which can potentially be predicted early by observing Global Longitudinal Strain (GLS). The relationship between HRV and GLS has not been extensively studied. Therefore, this study aimed to identify the relationship between HRV and GLS.

Methods. A cross-sectional study with a population of adult type 2 DM patients residing in Jakarta in December 2020. …

Infeksi Oportunistik Pada Pasien Hiv Yang Dirawat Inap Di Rsup Dr. Hasan Sadikin Bandung Tahun 2019-2022, Katarina Salma, Yovita Hartantri, Nisa Fauziah

Jurnal Penyakit Dalam Indonesia

Introduction. Human Immunodeficiency Virus (HIV) is a virus that infects and attacks the human immune system. The high morbidity and mortality rates in HIV patients can be attributed to various factors, one of which is the presence of opportunistic infections due to the weakened immune response, making HIV patients highly susceptible to other infections. This study aims to provide an overview of opportunistic infections in HIV patients hospitalized at Dr. Hasan Sadikin General Hospital in Bandung within the period of 2019-2022.

Methods. This descriptive observational study was conducted on 255 HIV patients with opportunistic infections who were hospitalized at dr. …

Penghambat Kanal Kalsium Sebagai Kontrol Glukosa Darah Pada Insulinoma: Sebuah Laporan Kasus, Nadhira Nizam, Ryan Tresna Putra, Anshari Saifuddin Hasibuan

Jurnal Penyakit Dalam Indonesia

Insulinoma is a rare neuroendocrine tumor of the pancreas arising from β-cells, leading to excessive insulin secretion and resultant hypoglycaemia. Surgical resection is the first-line treatment for insulinoma, but when surgery is not feasible, medical therapy is an important option. Calcium channel blockers (CCBs) such as verapamil can inhibit insulin release from β-cells and have been proposed as an adjunct therapy to help control blood glucose levels in insulinoma. We report a 43-year-old man who presented to the emergency department with decreased consciousness due to hypoglycaemia. His capillary blood glucose at home was 35 mg/dL, about 8 hours after his …

Advanced Hiv Disease: Wajah Hiv Yang Hampir Terlupakan, Evy Yunihastuti, Bramantya Wicaksana

Jurnal Penyakit Dalam Indonesia

No abstract provided.

Efek Hipnoterapi Untuk Meningkatkan Kualitas Hidup Pada Pasien Penyakit Ginjal Kronik: Suatu Laporan Kasus Berbasis Bukti, Aisha Putri Chairani, Rudi Putranto, Hamzah Shatri, Maruhum Bonar Hasiholan Marbun, Edward Faisal, Vinandia Irvianita, Diah Martina

Jurnal Penyakit Dalam Indonesia

Chronic Kidney Disease (CKD) is a condition of kidney damage with a decrease in glomerulus filtration rate of 60 ml/min/1.73 m3 for a duration of more than three months. CKD is closely related to the patient’s quality of life because the patient must carry out various lifestyle restrictions to slow the progression of kidney damage. Lifestyle restrictions often cause problems in the psychosocial field that increase the severity of symptoms and decrease kidney function faster. This evidence-based case review was compiled to determine the effectiveness of hypnotherapy in improving the quality of life of CKD patients. Literature searches were conducted …

Pencegahan Sindrom Delirium Akut Pada Pasien Lansia Di Rawat Inap, Vera Vera

Jurnal Penyakit Dalam Indonesia

Acute delirium syndrome is often found in hospitalized older patients, requiring longer hospital stay and higher hospital cost. Studies showed that 40% of these delirium cases in older patients may be prevented with multicomponent intervention based on National Institute for Health and Clinical Excellence (NICE) and Hospital Elder Life Program (HELP) guidelines. This article explained multicomponent intervention, which includes protocols for disorientation, dehydration, hypoxia, constipation, malnutrition, pain control, infection control, infection prevention, drugs evaluation, early mobilization, and education for patients’ family / caregiver. Prevention of acute delirium syndrome in hospitalized older patients will reduce the medical cost and distress among …

Status Gizi Sebagai Faktor Risiko Mortalitas Di Rumah Sakit Pada Pasien Lanjut Usia Pasca Reseksi Tumor Kolorektal, Ayu Fitri Sekar Wulandari, Parish Budiono, Yudo Murti Mupangati

Jurnal Penyakit Dalam Indonesia

Introduction. Malnutrition in elderly patients, particularly those with colorectal cancer, increases morbidity, mortality, and length of hospital stay due to metabolic dysregulation and hypermetabolic perioperative response, affecting wound healing, infection risk, postoperative complications, and nutritional deficits. This study aimed to analyze whether nutritional status is a risk factor for in-hospital mortality in elderly patients after colorectal tumor resection.

Methods. A case-control matching study was conducted on elderly patients who underwent colorectal tumor resection, using secondary data from elderly inpatients at Dr. Kariadi General Hospital from January 2020 to April 2024. The collected data were analyzed using bivariate analysis …

Harnessing Sociodemographic And Anthropometric Insights To Predict Type 2 Diabetes Risk: A Machine Learning Approach, Rico Kurniawan, Rezki Yunanda, Okky Assetya Pratiwi

Jurnal Biostatistik, Kependudukan, dan Informatika Kesehatan

The complexity of diabetes makes early diagnosis and effective management challenging for healthcare settings. This study developed and evaluated models using machine learning algorithms to predict the risk of diabetes. The data were primarily sourced from the Indonesia Family Life Survey (IFLS). Diabetes status was identified using A1c whole blood sample values (A1c WBS ³5.7%). Sociodemographic and anthropometric factors were set as predictors, most of which were significantly correlated with diabetes status. Discrete machine learning algorithms such as decision tree, k-nearest neighbors (KNN), random forest (RF), naïve Bayer, support vector machine (SVM), and neural network (MLP) were applied to construct …

Analisis Kepuasan Pengguna Simrs Pada Klaim Jkn Di Rsud Khidmat Sehat Afiat, Kota Depok Tahun 2023, Robiatul Adawiyah, R Sutiawan

Jurnal Biostatistik, Kependudukan, dan Informatika Kesehatan

Keberlangsungan klaim JKN di RSUD Khidmat Sehat Afiat Kota Depok sekurang-kurangnya harus didukung oleh SIMRS yang dapat diintegrasikan dengan E-Klaim INA-CBG’s dan V-Claim. Maka pada tahun 2019 SIMRS dilakukan integrasi dengan kedua sistem informasi tersebut guna meningkatkan keberhasilan klaim JKN. Namun, sejak SIMRS diintegrasi, hingga saat ini belum pernah dilakukan analisis. Padahal, E-Klaim INA-CBG’s dan V-Claim terus mengalami perubahan yang menjadikan banyaknya fitur yang belum tersedia pada SIMRS yang berujung membuat proses pengajuan klaim JKN menjadi terhambat. Desain penelitian ini menggunakan teori Delone dan McLean dengan jenis penelitian kuantitatif dan pendekatan cross-sectional. Pengambilan sampel menggunakan proportional stratified random sampling …

Peran Tempat Persalinan Dalam Inisiasi Menyusu Dini: Analisis Survei Demografi Dan Kesehatan Indonesia Tahun 2017, Siti Sunya Kumala, Besral Besral

Jurnal Biostatistik, Kependudukan, dan Informatika Kesehatan

Cakupan inisiasi menyusu dini (IMD) di Indonesia lebih rendah dibandingkan rata-rata ASEAN. Padahal cakupan persalinan di fasilitas kesehatan dan dibantu oleh tenaga kesehatan telah melampaui 70%. Penyedia layanan kesehatan menjadi faktor pendukung ibu untuk melakukan IMD. Penelitian ini bertujuan untuk mengetahui peran tempat persalinan dalam IMD di Indonesia. Penelitian dilakukan dengan desain potong lintang, dan menggunakan data Survei Demografi Kesehatan Indonesia tahun 2017. Sampel penelitian adalah wanita usia 15-49 tahun dari seluruh provinsi di Indonesia. Regresi logistik ganda dilakukan untuk menganalisis IMD dari berbagai tempat persalinan. Proporsi IMD pada tahun 2017 adalah 60,7%. Proporsi IMD paling banyak di poskesdes/polindes (72,8%), …

Vaccination As A Protective Factor Against Hospitalization For Sars-Cov-2 Infections: An Observational Study Using Surveillance Data, Chandrayani Simanjorang, Kristin Mutiara Tarigan, Diva Anita Churiana Sudrajat, Rana Zahra Raniyah Wangsawinangun, Asy Syifa Anwari Zahra

Jurnal Biostatistik, Kependudukan, dan Informatika Kesehatan

Death due to SARS-CoV-2 generally occurs in patients requiring hospital care (hospitalization). However, it is still unclear whether vaccination acts as a protective factor against hospitalization in SARS-CoV-2 patients in Indonesia. This study examines the association between vaccination and hospitalization among SARS-CoV-2 patients. It employs a quantitative, cross-sectional design using secondary data from SARS-CoV-2 surveillance records at the Jakarta Health Agency (January–August 2021). Findings show that patients who received the 1st vaccine dose had a 0.34 times lower risk of hospitalization compared to unvaccinated individuals (aPOR=0.34; 95% CI=0.31–0.38). Those who received the 2nd dose had an even lower risk (aPOR=0.16; …

Dampak Tradisi Pemberian Nasi Papahan Terhadap Kesehatan Bayi Usia 6-24 Bulan: Literature Review, Sakinah Hadirama, Tri Krianto Karjoso

Jurnal Biostatistik, Kependudukan, dan Informatika Kesehatan

Praktik pemberian nasi papahan seringkali dianggap sebagai bentuk kasih sayang antara ibu kepada bayi dan bertujuan untuk memudahkan bayi dalam mengonsumsi makanan, padahal hal tersebut tidak baik bagi kesehatan karena dapat menjadi media penularan penyakit apabila ibu menderita penyakit menular tertentu sehingga mengakibatkan gangguan kesehatan pada bayi, terutama saat berusia 6-24 bulan karena saat itu adalah masa golden age (periode keemasan) pada bayi yang menjadi proses penting dalam tumbuh kembang anak. Tujuan penelitian ini adalah untuk mengetahui dampak kesehatan yang ditimbulkan akibat tradisi pemberian nasi papahan kepada bayi usia 6-24 bulan. Metode yang dilakukan adalah kajian literatur melalui database publikasi …

Factors Affecting Nurse Retention In A Private Healthcare System In Malaysia, Zarin Ikmal Zan Mohd Zain, Annamma Kunjukunju, Govethamma Subramaniam, Nur Izzana Tajuddin

Jurnal Keperawatan Indonesia

Nurse retention has become increasingly challenging in the post-pandemic era, particularly for private hospitals. This study aimed to identify the significant predictors of nurse retention in selected private hospitals in Malaysia. A quantitative, descriptive, cross-sectional design was employed. A pre-validated, self-administered questionnaire, distributed via Google Forms, was used for data collection. The respondents included 532 registered nurses employed at three private hospitals in Malaysia. Data analysis was conducted using descriptive statistics and correlation studies, including Spearman’s rho and multiple regression analysis. Among the participants, 54% reported good job satisfaction, 27.37% expressed organizational commitment, 25.97% were satisfied with human resource practices, …

The Relationship Between Climate And Dengue Hemorrhagic Fever Incidence Rate In Malang Regency In 2022-2024, Aticobhita C. Pramono, Suprijandani Suprijandani, Marlik Marlik, Pratiwi Hermiyanti

Jurnal Epidemiologi Kesehatan Indonesia

Dengue Hemorrhagic Fever (DHF) is an infectious disease that poses a public health problem in tropical regions and is influenced by climatic factors such as temperature, rainfall, humidity, and wind speed. In 2023, Malang Regency recorded 1,018 cases with an incidence rate (IR) of 38.2 per 100,000 population. This study aims to analyze the relationship between climatic factors and the DF IR for the 2022–2024 period using an ecological design and Spearman’s correlation analysis. Climate data were obtained from the BMKG, while DF data were obtained from the Health Office. The results showed that only air temperature was significantly associated …

Video Animation: Improving Older Adults Patients Knowledge And Motivation Related To Hypertension Diet, Gusti Ayu Kade Budiarti, Sri Susanty, Ruslan Madjid, Ramadhan Tosepu

Jurnal Keperawatan Indonesia

Hypertension is a dangerous medical condition that can increase the risk of heart, brain, and renal problems, among other issues. A balanced diet is an essential hypertension control intervention. This study seeks to examine the efficiency of employing animation media to explain the application of diets that prevent hypertension and boost the understanding and motivation of senior patients at Bahteramas Regional General Hospital. In both the control and intervention groups, a quantitative-quasi-experimental design was adopted, with pre-test and post-tests. Data was obtained via questionnaires from 92 respondents chosen using a purposive sampling approach, with 46 in the intervention group from …

The Intensity Of 10-Minute Classroom Physical Activity Breaks In Elementary School Children, Jeffery J. Honas, Amanda N. Szabo-Reed, Joe Sherman, Anna Rice, Robert Montgomery, Ken Murfay, Richard A. Washburn, Joseph E. Donnelly

International Journal of Physical Activity and Health

This study examined the intensity of different physical activity (PA) breaks for elementary school children in a simulated classroom setting. Researchers compared the energy expenditure (Kcals/min, METs) of PA breaks developed for the Physical Activity Across the Curriculum (PAAC-3) program, delivered via video or in-person, to commercially available GoNoodle^© videos. 71 children (age 9.0 ± 1.1 yrs., 47 males, 24 females, 18% minority) participated in 10-minute PA breaks. The intensity of activity breaks was assessed using a COSMED® K5 portable indirect calorimeter (weight ~ 1 kg) (COSMED®, Rome, Italy) and and portable accelerometer (ActiGraph GT3X+; ActiGraph LLC, Pensacola, FL) …

Assessment Of Nurses’ Knowledge Of Multiple Sclerosis In Morocco, Rachid Lotfi, Hind Bel Amgharia, Mourad Chikhaoui, Abdeslam El Kardoudi, Fatiha Chigr

Jurnal Keperawatan Indonesia

Nurses are essential in early detection, education, symptom management, treatment administration, and care coordination for patients with multiple sclerosis (MS). This role requires both theoretical and practical knowledge. This study evaluates the knowledge level among nurses regarding multiple sclerosis in Morocco. We conducted this cross- sectional study on 326 nurses in Morocco using a purposive sampling method, which involves selecting nursing specialties that have direct contact with patients with MS, aiming to target the most relevant professionals for the study. The data are collected using an anonymous questionnaire distributed individually to participants. We opted for multi- variable logistic regression models …

Resilience, Social Support, And Quality Of Life Among People Living With Hiv/Aids, Firman Firman, Sri Yona, Agung Waluyo

Jurnal Keperawatan Indonesia

One of the most common challenges faced by people living with human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) is a low quality of life, particularly during the coronavirus disease 2019 (COVID-19) pandemic, as they are considered a vulnerable group. This study aimed to examine the relationship between resilience, social support, and quality of life among people living with HIV/AIDS during the pandemic. Conducted as a cross- sectional study, it involved 433 respondents. Data collection was carried out using a questionnaire, with Connor–Davidson Resilience Scale-25 (CD-RISC-25), Multidimensional Scale of Perceived Social Support (MSPSS), and World Health Organization Quality of Life–HIV Brief …

Evaluation Of The Use Of Structural Gamification-Based Applications By Users In Makassar City, Indonesia, Andi Fitria Idham, Ade Putrawan, Firdi Athaya, Fitrah Ramadhan, Arnis Puspitha Rasyid

Jurnal Keperawatan Indonesia

Structural gamification is a trending concept in today’s application landscape that leverages various elements and features from game design for nongame contexts. This concept has become increasingly common in various health applications today, such as Lose It!, Fat Secret, and Google Fit. This study aims to evaluate respondents’ use of structural gamification- based health applications. The research method employed in this study is quantitative and descriptive, involving data collection through questionnaires administered from July 2023 to September 2023 in Makassar City, Indonesia. The research results indicate that 90% of the respondents appreciated the ease of access and attractive interface of …

Mothers’ Characteristics And Children's Diarrhea Between 2010-2020 In Rwanda, Amans Ntakarutimana Dr., Patrick A. Tschida Dr.

Journal of Social, Behavioral, and Health Sciences

Mothers’ characteristics influence children’s health and development. We conducted a cross-sectional study to assess the influence of mothers’ education level, employment status, and exposure to domestic violence on diarrhea among children under 5 years old using secondary data from 2010, 2015, and 2020 Rwanda Demographic Health Surveys. We used stratified descriptive statistics, pairwise comparisons, and logistic regression designs to assess (a) the prevalence of mothers per education level, employment status, and exposure to domestic violence; (b) their variation over time; and (c) their influence on diarrhea among children under 5 years old between 2010 and 2020 in Rwanda. According to …

Development And Analysis Of The Kinematic-Dynamic Model Of The Rehabilitation Exoskeleton System, Umidjon Abdumutalipovich Takabaev, Zafar Botirovich Juraev

Technical science and innovation

Designing modern rehabilitation exoskeleton systems requires a comprehensive study of human-machine interactions. In this process, creating kinematic and dynamic mathematical models of the system is extremely important. In this paper, we develop mathematical models that describe rehabilitation exoskeleton systems' kinematic and dynamic properties. Based on the Denavit-Hartenberg method we construct kinematic model of the exoskeleton system. The method gave us to determine the coordinate system for each joint. Furthermore, we also study the motion range of joints of the exoskeleton. Modeling the dynamic properties of the system performed with the second-order Lagrange equation. The exoskeleton construction consisting of knee, thigh, …

Profiling Competitive Malaysian Archers: Musculoskeletal Injuries And Related Risk Factors, Ambusam Subramaniam, Fariza Zainudin Fairus, Mon Redee Sut Txi

Baltic Journal of Health and Physical Activity

Background: Archery requires precision, strength, stamina, and attention, yet musculoskeletal injury data is scarce. The study aimed to profile the musculoskeletal injuries and the associated risk factors among Malaysian archers. Methods: A cross-sectional approach was used to recruit 165 elite archers. The Standardized Nordic Questionnaire (SNQ), adapted risk factors questionnaire, Pittsburgh Sleep Quality Index (PSQI), and Depression Anxiety Stress Questionnaire (DASS-21) were used to screen participants. Results: Shoulder (drawing arm) (54.5%), shoulder (bow arm) (56.4%), upper back (38.8%), lower back (38.2%), and neck (37.6%) musculoskeletal injuries were common. The injuries were reported during training (85.5%), accumulation/overuse injuries (72.1%), and sudden …

Continuous Renal Replacement Therapy Training In The Icu: An Evidence-Based Practice Proposal, Joseph C. Brabec

SACAD: Scholarly Activities

Continuous renal replacement therapy (CRRT) is a complex, high-risk intervention used in intensive care units (ICUs) for critically ill patients with acute kidney injury and hemodynamic instability. ICU nurses are responsible for initiating, monitoring, troubleshooting, and discontinuing CRRT while providing continuous bedside care (Richardson & Whatmore, 2015). However, variability in training frequency and competency validation remains a significant gap, potentially contributing to errors and adverse patient outcomes. Guided by the Iowa Model of Evidence-Based Practice, a literature review was conducted to identify best practices for CRRT training. A proposed evidence-based practice (EBP) project was developed to implement a standardized CRRT …

Poor Cancer Prevention And Detection In Zimbabwe, Kenyon C. Chipman

Journal of Nonprofit Innovation

Abstract

In the aftermath of the HIV/AIDS epidemic, Sub-Saharan Africa, particularly Zimbabwe, has witnessed a surge in noncommunicable diseases such as cancer. Despite the decline in HIV/AIDS and other cancer-associated illnesses like HPV, these diseases have set the stage for a growing cancer epidemic. Key contributing factors to this rise include a lack of knowledge about cancer among both patients and health professionals, the prevalence of cancer-associated communicable diseases, and limited accessibility to early detection and prevention services and resources. These factors have led to late diagnoses, increased burden on the healthcare system, and adverse effects on individuals and families. …

Psychological Influence Of Acne Vulgaris Among Female Students Of University Of Poonch Rawalakot Azad Jammu And Kashmir, Pakistan, Faryal Hanif, Ahmed Hussain, Ehsan Ali, Muhammad Rasheed

Journal of Bioresource Management

This study aimed to assess the prevalence of acne vulgaris among female students at the University of Poonch, Rawalakot, and to evaluate its impact on their quality of life using the Dermatology Life Quality Index (DLQI). A cross-sectional survey was conducted from July to August 2022, involving a total of 2000 female students. Out of these, 400 individuals were clinically diagnosed with acne vulgaris, indicating a prevalence rate of 20 %. The participants completed the DLQI questionnaire, which evaluates the psychological and social effects of dermatological conditions. The data obtained were analyzed to assess the influence of acne on various …

Study On Predisposing Factors And Control Measures Against Cryptosporidiosis In Buffalo Calves At Cattle Colony Hyderabad, Sindh, Pakistan, Ali Ul Murtaza, Abdul Latif Bhutto, Jam Kashif Zaman, Mansoor Tariq, Amjad Hussain Mirani, Riaz Ahmed Laghari, Pervez Ahmed Khoso, Muhammad Mohsen Rahimoon, Abdul Saboor, Fayaz Hussain

Journal of Bioresource Management

The current study looked at the variables affecting the frequency of Cryptosporidium Parvum in buffalo calves at the Hyderabad Cattle Colony. From calves, 100 fecal samples were taken in total, preserved, and analyzed using direct smear and Ziehl-Neelsen staining methods. 74 percent of the samples tested positive for Cryptosporidium Parvum. Disease rates were higher in Nili Ravi calves (86 %) compared to Kundhi calves (62 %), with a statistically significant difference (p

Review On Treatment Outcome Of Patient With Acute Bacterial Meningitis In Pediatrics, Uswa Insaf, Faiza Waseem, Nadia Iqbal, Tehseen Riaz, Irfan Bashir, Waqas Akram

Journal of Bioresource Management

Antibiotic treatment improves outcomes of treatment, but extensively available antibiotics efficiency is vulnerable by globally appearance of development of multidrug-resistant bacteria. An infectious etiology arises, such as fungi, bacteria, viruses, mycobacteria, or parasites, or be related with cancer, autoimmunity, or medications reaction. The causative organism was recognized by most patients treated with antibiotics, culture of the CSF and blood, by countercurrent immune-electrophoresis of fluids. Neisseria meningitidis, Hemophilus influenzae b and Streptococcus pneumoniae are the commonest causes of bacterial meningitis. Bacterial meningitis has adequately extreme in the pediatrics people of developing countries. Many people with bacterial meningitis don't have any …

Identification Of Xanthine Oxidase Inhibitors In Single-Clove Black Garlic Using Metabolomics And Molecular Docking Approaches, Abdul Aziz Setiawan, Shirly Kumala, Dian Ratih Laksmitawati, Ari Yuniarto, Nancy Dewi Yuliana

Makara Journal of Science

Black garlic is produced through controlled fermentation under specific temperature and humidity conditions, during which the Maillard reaction enhances its sensory properties and bioactivity. The anti-hyperuricemic potential of single-clove black garlic (SBG) remains unexplored. This study combined Ultra High-Performance Liquid Chromatography–High Resolution Mass Spectrometry-based metabolomics and an in-silico approach to identify the potential xanthine oxidase inhibitors (XOI) in SBG. Methanolic extracts (10 ppm) exhibited xanthine oxidase inhibition ranging from 50.09% to 68.01%, which is comparable to allopurinol (78.74%) at the same concentration. Metabolomic profiling tentatively identified 45 compounds, and orthogonal partial least squares analysis revealed seven metabolites as strongly correlated …

Impact Of Using The Multi-Ethnic Global Lung Initiative As A Spirometry Reference Equation: Retrospective Cross-Sectional Study In Egyptians, Mohamed Gs. El-Shiekh

Journal of Medicine in Scientific Research

Context: Spirometry interpretation is largely affected by the reference equation. European Coal and Steel Community/European Respiratory Society reference equation 93 (ECSC-ERS93) is widely used in Egypt, despite the endorsement of multiethnic global lung initiative equation (GLI-2012) by many international societies as a reference. Aim: We aimed to investigate the interpretive impact of shifting from ECSC-ERS93 to GLI-2012 among Egyptians. Methods: Acceptable pre-bronchodilator spirometry tests for Egyptian subjects, obtained between January 2022 and July 2024 were included, excluding those with age and anthropometric limits of ECSC-ERS 93 equation. Interpretation of spirometric results (normal, preserved ratio impaired spirometry (PRISm), spirometric obstruction, spirometric …

Novel Drug Approvals 2024, Hanh Motilall, Kelley Maberry, Connor Quinter

Transformative Medicine

In 2024, the Food and Drug Administration (FDA) Center for Drug Evaluation and Research (CEDR) approved 50 new drugs. As healthcare professionals, staying up to date on new therapies is vital. There are a wide range of medications that fall into several categories; therefore every professional can find a medication that pertains to their field. Three medications in particular will be described in detail outlining their background, the clinical trials highlighting their efficacy and safety, and lastly the prescribing information. The three medications are as follows, Xanomeline/Trospium Chloride (Cobenfy),Sotatercept-csrk (Winrevair) and Suzetrigine (Journavx).

Xanomeline/trospium chloride (Cobenfy) is a first of …