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Articles 55831 - 55860 of 62662

Full-Text Articles in Medicine and Health Sciences

การทดสอบนํ้าตาลในปัสสาวะโดยใช้แถบกระดาษชุบสารเคมีที่ผลิตขึ้นเอง, ปิยะรัตน์ โตสุโขวงศ์, ศรีสกุล เกรียงศิริ, ฃนิษฐ บูรณศิริ, วิทยา ศรีดามา, จวงจันทร์ ชัยธชวงศ์ Aug 1987

การทดสอบนํ้าตาลในปัสสาวะโดยใช้แถบกระดาษชุบสารเคมีที่ผลิตขึ้นเอง, ปิยะรัตน์ โตสุโขวงศ์, ศรีสกุล เกรียงศิริ, ฃนิษฐ บูรณศิริ, วิทยา ศรีดามา, จวงจันทร์ ชัยธชวงศ์

Chulalongkorn Medical Journal

No abstract provided.

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Distribution Of Vertebrates Of The Bighorn Canyon National Recreation Area, Stanley H. Anderson, Wayne A. Hubert, Craig Patterson, Alan J. Redder, David Duvall Jul 1987

Distribution Of Vertebrates Of The Bighorn Canyon National Recreation Area, Stanley H. Anderson, Wayne A. Hubert, Craig Patterson, Alan J. Redder, David Duvall

Great Basin Naturalist

During a survey of the vertebrates in the Bighorn Canyon National Recreation Area, 46 mammal, 210 bird, 9 reptile, 5 amphibian, and 28 fish species were found. Habitat structure and moisture were two environmental variables associated with species numbers across this 1,820-ha area. Eight distinct habitats were evaluated. In coniferous forests, 27% of the birds and 54% of the mammals were observed. Sagebrush/grasslands and upland shrublands were very arid and had relatively few vertebrates. Five introduced game birds occurred in sagebrush habitat. Riparian and wetland habitats had the largest number of unique vertebrates, 38 and 77 respectively. The establishment of …

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Thyroid C-Cell Hyperplasia And Micronodules In Close Relatives Of Men-2 A Patients: Pitfalls In Early Diagnosis And Reevaluation Of Criteria For Surgery, Cees J. M. Lips, John R. Leo, Marianne J. H. Berends, Werner H. Minder, A. P. Roeland Blok, Rolf A. Geerdink, Wil H. L. Hackeng, Jan M. M. Roelofs, Hans F. A. Vasen, Jan K. Vette Jul 1987

Thyroid C-Cell Hyperplasia And Micronodules In Close Relatives Of Men-2 A Patients: Pitfalls In Early Diagnosis And Reevaluation Of Criteria For Surgery, Cees J. M. Lips, John R. Leo, Marianne J. H. Berends, Werner H. Minder, A. P. Roeland Blok, Rolf A. Geerdink, Wil H. L. Hackeng, Jan M. M. Roelofs, Hans F. A. Vasen, Jan K. Vette

Henry Ford Hospital Medical Journal

In a large family with multiple endocrine neoplasia rype 2 A (MEN-2 A), 20 patients were identified by the diagnosis of medullary thyroid carcinoma (MTC) and/or pheochromocytomas. Another five subjects had neck surgery on the basis of slightly increased results of a C-cell provocative test. Retrospectively, however, although the immunohistochemical diagnosis of C-cell hyperplasia was confirmed, the diagnosis of MEN-2 was doubtful in these five subjects, and the C-cell hyperplasia observed was probably within the limits of normal variation. The occurrence of C-cell hyperplasia in a normal population was investigated by a C-cell provocative test, as well as in random …

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การแก้ใขภาวะสายตาสั้น, ศิริพัช อุบลสิงห์ Jul 1987

การแก้ใขภาวะสายตาสั้น, ศิริพัช อุบลสิงห์

Chulalongkorn Medical Journal

No abstract provided.

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อันตรายจากเสียง, กรรณิการ์ ชาญวนิชวงศ์ Jul 1987

อันตรายจากเสียง, กรรณิการ์ ชาญวนิชวงศ์

Chulalongkorn Medical Journal

No abstract provided.

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ความหนาตรงกลางของกระจกตาดำในคนไทยที่สายตาสั้น, ธวัชชัย ปานเสถียรกุล, จวงจันทร์ ชันซื่อ Jul 1987

ความหนาตรงกลางของกระจกตาดำในคนไทยที่สายตาสั้น, ธวัชชัย ปานเสถียรกุล, จวงจันทร์ ชันซื่อ

Chulalongkorn Medical Journal

No abstract provided.

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การศึกษานํ้าในช่องท้องในผู้ป่วยโรคตับเรื้อรัง, นุสนธิ์ กลัดเจริญ, สถาพร มานัตสถตย์, สัจพันธ์ อิศรเสนา, พรรณพิศ สุวรรณกูล, ผ่องพรรณ นันทาภิสุทธิ์, วิศิษฐ์ อุดมพาณิชย์ Jul 1987

การศึกษานํ้าในช่องท้องในผู้ป่วยโรคตับเรื้อรัง, นุสนธิ์ กลัดเจริญ, สถาพร มานัตสถตย์, สัจพันธ์ อิศรเสนา, พรรณพิศ สุวรรณกูล, ผ่องพรรณ นันทาภิสุทธิ์, วิศิษฐ์ อุดมพาณิชย์

Chulalongkorn Medical Journal

No abstract provided.

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คึกษาย้อนหลังผู้ป่วย Osteochondromas 78 ราย, พิเชฐ สัมปทานุกุล Jul 1987

คึกษาย้อนหลังผู้ป่วย Osteochondromas 78 ราย, พิเชฐ สัมปทานุกุล

Chulalongkorn Medical Journal

No abstract provided.

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ความก้าวหน้าในการให้บริการทางจักษุวิทยา, ประจักษ์ ประจักษ์เวช Jul 1987

ความก้าวหน้าในการให้บริการทางจักษุวิทยา, ประจักษ์ ประจักษ์เวช

Chulalongkorn Medical Journal

No abstract provided.

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ปัญหาของโสต สอ นาสิกแพทย์ต่างจังหวัดกับการผ่าตัดมะร็งบริเวณศรีษะและคอ, คเณศร์ แวววิจิต Jul 1987

ปัญหาของโสต สอ นาสิกแพทย์ต่างจังหวัดกับการผ่าตัดมะร็งบริเวณศรีษะและคอ, คเณศร์ แวววิจิต

Chulalongkorn Medical Journal

No abstract provided.

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การวินิจฉัยมะเร็งปากมดลูกระยะแรกด้วยเครื่องมือ Colposcope : รายงานเบื้องต้น, สมชัย นิรุตติศาสน์, ไพโรจน์ วิทูรพณิชย์, วลัยภรณ์ วจนะวิศิษฐ, สุขตา สิริวันต์ Jul 1987

การวินิจฉัยมะเร็งปากมดลูกระยะแรกด้วยเครื่องมือ Colposcope : รายงานเบื้องต้น, สมชัย นิรุตติศาสน์, ไพโรจน์ วิทูรพณิชย์, วลัยภรณ์ วจนะวิศิษฐ, สุขตา สิริวันต์

Chulalongkorn Medical Journal

No abstract provided.

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Malignant External Otitis : รายงานผู้ป่วย 1 ราย, คเณศร์ แวววิจิต, สุธี พิสิฐพยัต Jul 1987

Malignant External Otitis : รายงานผู้ป่วย 1 ราย, คเณศร์ แวววิจิต, สุธี พิสิฐพยัต

Chulalongkorn Medical Journal

No abstract provided.

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Adie's Syndrome, สมชาย คำพะนาง, อรุณี เลิศชวนะกุล Jul 1987

Adie's Syndrome, สมชาย คำพะนาง, อรุณี เลิศชวนะกุล

Chulalongkorn Medical Journal

No abstract provided.

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กลไกการป้องกันของปอด, สมเกียรติ วงษ์ทิม Jul 1987

กลไกการป้องกันของปอด, สมเกียรติ วงษ์ทิม

Chulalongkorn Medical Journal

No abstract provided.

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Plasma And Tumor Levels Of Somatostatin (Srif) And Somatostatin Immunochemistry In Medullary Thyroid Carcinoma: Apparently Discrepant Preliminary Results, B. Franc, J. A. Chayvialle, E. Modigliani, C. Calmettes, B. Caillou, N. Dutrieux-Berger, C. Houdent, M. Kujas Jun 1987

Plasma And Tumor Levels Of Somatostatin (Srif) And Somatostatin Immunochemistry In Medullary Thyroid Carcinoma: Apparently Discrepant Preliminary Results, B. Franc, J. A. Chayvialle, E. Modigliani, C. Calmettes, B. Caillou, N. Dutrieux-Berger, C. Houdent, M. Kujas

Henry Ford Hospital Medical Journal

Eighteen cases of medullary thyroid carcinoma (MTC) (11 hereditary) had parallel measurements of basal plasma levels of somatostatin (SRIF), levels of SRIF extracted from fresh tumor tissue (radioimmunoassay), and immunohistochemistry (peroxidase-antiperoxidase method) using an anti-SRIF antibody on paraffin sections. Immunohistochemistry disclosed some cell positivity in nine cases (50%). Plasma levels of SRIF were above normal (> 50 pg/mL expressed in terms of the 14 amino acid SRIF peptide) in only two of 12 patients. Extraction of fresh tumor tissue detected SRIF in 60% of our cases: two patients > l.200pg/mg (equivalents 14). with the other positive values ranging between 13 and …

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Impact Of Prospective Screening For Multiple Endocrine Neoplasia Type 2, Robert F. Gagel, Armen H. Tashjian Jr., Tim Cummings, Nick Papathanasopoulos, Seymour Reichlin Jun 1987

Impact Of Prospective Screening For Multiple Endocrine Neoplasia Type 2, Robert F. Gagel, Armen H. Tashjian Jr., Tim Cummings, Nick Papathanasopoulos, Seymour Reichlin

Henry Ford Hospital Medical Journal

Prospective annual screening for hereditary medullary thyroid carcinoma (MTC) in the J-kindred, currently a 117-member family with multiple endocrine neoplasia type 2A, began in 1969. During the initial screening, 12 patients were found to have MTC. Subsequent screening has detected C-cell abnormalities (C-cell hyperplasia or microscopic MTC) in 22 of 23 addilional family members thyroidectomized for abnormal calcium- or pentagastrin-provocative calcitonin (CT) test results. Seven of the initial 12 patients thyroidectomized in 1970 to 1971 and 19 of 23 individuals thyroidectomized since 1971 remain disease-free by all criteria; three patients thyroidectomized since 1971 have had clearly abnormal serum CT measurements …

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Subtotal Adrenalectomy In Multiple Endocrine Neoplasia Type 2, Bertil Hamberger, Margareta Telenius-Berg, Bjorn Cedermark, Staffan Grondal, Bengt-Goran Hansson, Sigbritt Werner Jun 1987

Subtotal Adrenalectomy In Multiple Endocrine Neoplasia Type 2, Bertil Hamberger, Margareta Telenius-Berg, Bjorn Cedermark, Staffan Grondal, Bengt-Goran Hansson, Sigbritt Werner

Henry Ford Hospital Medical Journal

We report two patients in whom pheochromocytoma was treated by subtotal adrenalectomy leaving a rim of vascularized cortical tissue in situ. Both patients are doing well without cortisol supplementation although they have subnormal cortisol responses to ACTH stimulation.

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Application Of Minisatellite Dna Probes To Linkage In Men-2, Bruce A. J. Ponder, Alec J. Jeffreys, Nicola E. Hartley, Clare Carter, Douglas F. Easton, Hakan Telenius, Margareta Telenius-Berg Jun 1987

Application Of Minisatellite Dna Probes To Linkage In Men-2, Bruce A. J. Ponder, Alec J. Jeffreys, Nicola E. Hartley, Clare Carter, Douglas F. Easton, Hakan Telenius, Margareta Telenius-Berg

Henry Ford Hospital Medical Journal

We describe the potential benefits and the limitations of the use of highly polymorphic minisatellite DNA probes for genetic linkage analysis of multiple endocrine neoplasia type 2A (MEN-2 A). The advantage of these probes is that up to 34 loci can be examined in a single experiment, and since the loci are highly polymorphic, almost every individual in every family is informative. The disadvantage is that the DNA fragment lengths of the alleles at any given locus differ from one family to another, so that families cannot be combined, and large single sibships are needed to obtain significant linkage data. …

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One Large Kindred Excludes A Locus For Multiple Endocrine Neoplasia Type 2a From About 25% Of The Human Autosomal Genetic Map, Andrew J. Pakstis, Judith R. Kidd, Carmela M. Castiglione, Beth A. Pletcher, Patricia D. Murphy, Lindsay A. Farrer, Myron Genel, Kenneth K. Kidd Jun 1987

One Large Kindred Excludes A Locus For Multiple Endocrine Neoplasia Type 2a From About 25% Of The Human Autosomal Genetic Map, Andrew J. Pakstis, Judith R. Kidd, Carmela M. Castiglione, Beth A. Pletcher, Patricia D. Murphy, Lindsay A. Farrer, Myron Genel, Kenneth K. Kidd

Henry Ford Hospital Medical Journal

This report presents pairwise linkage results from our search for the locus of the gene (MEN2A) for the multiple endocrine neoplasia type 2A (MEN-2A) syndrome in one large kindred (the N kindred), clearly segregating for an autosomal dominant form. About 25% of the autosomal genome is excluded when these new results are combined with those we have published previously. The genetic markers employed are distributed across at least 19 of the 22 autosomes. Seven genetic markers whose chromosomal locations are not yet established have also been studied.

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Immunohistochemistry In Medullary Thyroid Carcinoma: Prognosis And Distinction Between Hereditary And Sporadic Tumors, B. Franc, B. Caillou, A. M. Carrier, N. Dutrieux-Berger, J. Floquet, M. Houcke, E. Justrabo, F. Lange, A. Pages, C. Rigaud, A. Schwartz, M. Viennet, M. F. Lebodic Jun 1987

Immunohistochemistry In Medullary Thyroid Carcinoma: Prognosis And Distinction Between Hereditary And Sporadic Tumors, B. Franc, B. Caillou, A. M. Carrier, N. Dutrieux-Berger, J. Floquet, M. Houcke, E. Justrabo, F. Lange, A. Pages, C. Rigaud, A. Schwartz, M. Viennet, M. F. Lebodic

Henry Ford Hospital Medical Journal

In this retrospective study of 68 cases of medullary thyroid carcinoma (MTC), morphological features were studied, which could be helpful in prognosis and in the distinction between hereditary and sporadic forms of the disease. Necrosis within the tumors seemed to carry a poor prognosis. Bilateral MTC. unquestionable C-cell hyperplasia, glandular or follicular pattern, and thyroglobulin-positive cells seemed to be more prevalent in hereditary forms of the disease. A smaller proportion of calcitonin-immunoreactive cells were encountered in hereditary tumors than in sporadic tumors.

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Different Mechanisms Of Calcitonin, Calcitonin Gene-Related Peptide, And Somatostatin Regulation By Glucocorticoids In A Cell Culture Of Human Medullary Thyroid Carcinoma, Gilbert J. Cote, Robert F. Gagel Jun 1987

Different Mechanisms Of Calcitonin, Calcitonin Gene-Related Peptide, And Somatostatin Regulation By Glucocorticoids In A Cell Culture Of Human Medullary Thyroid Carcinoma, Gilbert J. Cote, Robert F. Gagel

Henry Ford Hospital Medical Journal

We have employed the TT cell line, a model for the human medullary thyroid carcinoma cell, lo study the regulation of peptide hormone production by glucocorticoids. Complementary DNA probes were used to measure the calcitonin (CT), CT gene-related peptide (CGRP), and somatostatin (SRIF) mRNA levels. Dose-response experiments in serum-free medium showed that dexamethasone (six-day treatment) lowered somatostatin (to 1% of basal) and CGRP mRNA (to 50% of basal) and stimulated CT mRNA (threefold to thirteenfold) with a half-maximal effective concentration of 10−8 M. Time course studies for cells continuously exposed to 10−6 M dexamethasone showed a rapid (within …

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Front Matter Jun 1987

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

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The Second International Workshop On Multiple Endocrine Neoplasia Type 2 Syndromes, Bruce A. J. Ponder, Charles E. Jackson Jun 1987

The Second International Workshop On Multiple Endocrine Neoplasia Type 2 Syndromes, Bruce A. J. Ponder, Charles E. Jackson

Henry Ford Hospital Medical Journal

No abstract provided.

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Screening In Medullary Thyroid Carcinoma, C. Calmettes Jun 1987

Screening In Medullary Thyroid Carcinoma, C. Calmettes

Henry Ford Hospital Medical Journal

The four-year experience of the French collaborative study on medullary thyroid carcinoma (MTC) has permitted improvement in family screening by a common discussion of data and a network of coordinators throughout France involved in the detection of new cases. Investigations have been directed at improving the discrimination between sporadic and hereditary forms of MTC and between individuals who have or have not inherited the disease within families.

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Men-2 Syndrome: The Value Of Screening And Central Registration; A Study Of Six Kindreds In The Netherlands, H. F. A. Vasen, A. C. Nieuwenhuijzen Kruseman, A. M. J. Moers, C. J. M. Lips, E. K. M. Beukers, W. M. Wiersinga, R. A. Geerdink Jun 1987

Men-2 Syndrome: The Value Of Screening And Central Registration; A Study Of Six Kindreds In The Netherlands, H. F. A. Vasen, A. C. Nieuwenhuijzen Kruseman, A. M. J. Moers, C. J. M. Lips, E. K. M. Beukers, W. M. Wiersinga, R. A. Geerdink

Henry Ford Hospital Medical Journal

Since 1975, six families with the MEN-2A syndrome including 66 patients have been identified in The Netherlands. All these patients underwent thyroidectomy for C-cell hyperplasia and/or medullary thyroid carcinoma (MTC); eight were symptomatic (Group A), 51 were relatives of patients found to be affected (Group B), and seven had had a negative screening test that became positive (Group C). To assess the effect of screening, we compared these groups with respect to the occurrence of metastatic MTC at thyroidectomy and the results of the postoperative calcitonin (CT) tests. We found that 87% of Group A, 37% of Group B; and …

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Characteristics Of A Family With The Men-2a Syndrome, Harm R. Haak, Arie C. Nieuwenhuijzen Kruseman Jun 1987

Characteristics Of A Family With The Men-2a Syndrome, Harm R. Haak, Arie C. Nieuwenhuijzen Kruseman

Henry Ford Hospital Medical Journal

Results of screening and follow-up in a family with the MEN-2A syndrome are described. Fourteen (83%) subjects at risk were affected with medullary thyroid carcinoma (MTC). Asymptomatic pheochromocytoma and parathyroid hyperplasia were found in two instances each. Intrathyroidal MTC without metastases was found in the four youngest subjects and was associated with normal basal but abnormal pentagastrin-stimulated calcitonin (CT) levels. In the ten subjects with abnormal basal CT levels, metastatic spread to at least regional lymph nodes was found. In eight of these ten subjects, total thyroidectomy with excision of affected lymph nodes and additional radioiodine did not return CT …

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Multiple Endocrine Neoplasia Type 2a: A Northern Ireland And Australian Family, David R. Hadden, Fergus O'Reilly, Laurence Kennedy, Colin Russell Jun 1987

Multiple Endocrine Neoplasia Type 2a: A Northern Ireland And Australian Family, David R. Hadden, Fergus O'Reilly, Laurence Kennedy, Colin Russell

Henry Ford Hospital Medical Journal

A Northern Ireland/Australian family with multiple endocrine neoplasia type 2A is described. Three members of the first generation studied have died, two men (aged 35 and 51) as a result of metastatic medullary thyroid carcinoma and one woman (the index case, aged 50) due to hypertensive complications during thyroidectomy from an undiagnosed pheochromocytoma. All members of this family found by screening to have either medullary thyroid carcinoma or pheochromocytoma, or both, have been asymptomatic for their disease.

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Screening For Early Asymptomatic Pheochromocytoma In Men-2, Margareta Telenius-Berg, Bertel Berg, Bertil Hamberger, Sten Tibblin Jun 1987

Screening For Early Asymptomatic Pheochromocytoma In Men-2, Margareta Telenius-Berg, Bertel Berg, Bertil Hamberger, Sten Tibblin

Henry Ford Hospital Medical Journal

Pheochromocytoma is a major cause of morbidity in multiple endocrine neoplasia type 2. We recommend a similar diagnostic screening approach for early asymptomatic pheochromocytoma as is generally accepted for asymptomatic medullary thyroid carcinoma. We present a new provocative test for early asymptomatic pheochromocytoma. Plasma epinephrine levels and epinephrine/dopamine ratios after physical exercise seem to have higher sensitivity than basal plasma catecholamine levels. Specificity is high especially for discrimination from neurovegetative lability, which is the clinically most important differential diagnosis.

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Calcitonin Gene-Related Peptide And Calcitonin In Men-2 And Sporadic Pheochromocytomas: An Immunohistochemical Study, Lis Johannsen, Henrik Daa Schroder, Soren Schifter Jun 1987

Calcitonin Gene-Related Peptide And Calcitonin In Men-2 And Sporadic Pheochromocytomas: An Immunohistochemical Study, Lis Johannsen, Henrik Daa Schroder, Soren Schifter

Henry Ford Hospital Medical Journal

Ten pheochromocytomas (five from patients with multiple endocrine neoplasia type 2 and five sporadic) were stained immunohistochemically with antibodies to calcitonin (CT) and calcitonin gene-related peptide (CGRP) by means of the peroxidase-antiperoxidase method. CGRP positive cells were found in variable numbers in all of the investigated tumors. No demonstrable difference was noted between the hereditary tumors and the sporadic tumors. Staining with CT antibody also showed cells with a positive reaction in eight of ten tumors. The distribution of the two peptides was similar, and in some cells their coexistence was visualized. Pheochromocytomas thus represent an alternative site to medullary …

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Calcitonin Gene Peptides: The Diagnostic Value Of Measurement In Medullary Thyroid Carcinoma, Samia I. Girgis, Catherine Lynch, Carmel J. Hillyard, John C. Stevenson, Patricia A. Hill, David W. R. Macdonald, Iain Macintyre Jun 1987

Calcitonin Gene Peptides: The Diagnostic Value Of Measurement In Medullary Thyroid Carcinoma, Samia I. Girgis, Catherine Lynch, Carmel J. Hillyard, John C. Stevenson, Patricia A. Hill, David W. R. Macdonald, Iain Macintyre

Henry Ford Hospital Medical Journal

The calcitonin gene encodes a family of peptides, at least three of which normally circulate in man: calcitonin (CT), a calcium-lowering hormone; katacalcin (KC), a peptide of unknown function; and calcitonin gene-related peptide (CGRP), a neuropeptide and potent vasodilator. In a study of 45 patients with medullary thyroid carcinoma (MTC), plasma CGRP was elevated in approximately 50% of cases. Furthermore, CGRP levels did not correlate with CT levels. However, plasma KC was elevated in all cases, with a good correlation with CT levels, as has been noted previously. Measurement of CT or KC appears to be superior to measurement of …

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