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Full-Text Articles in Medicine and Health Sciences

Pathophysiological Significance Of Blood Rheology, Oğuz Keri̇m Başkurt Jan 2003

Pathophysiological Significance Of Blood Rheology, Oğuz Keri̇m Başkurt

Turkish Journal of Medical Sciences

Tissue perfusion is determined by both blood vessel geometry and the rheological properties of blood. Blood is a non-Newtonian fluid, its viscosity being dependent on flow conditions. Blood and plasma viscosities, as well as the rheological properties of blood cells (e.g., deformability and aggregation of red blood cells), are influenced by disease processes and extreme physiological conditions. These rheological parameters may in turn affect the blood flow in vessels, and hence tissue perfusion. Unfortunately it is not always possible to determine if a change in rheological parameters is the cause or the result of a disease process. The hemorheology-tissue perfusion …


Reversible Conduction Block In Frog Sciatic Nerve For Three Different Concentrations Of Bupivacaine, Belgi̇n Büyükakilli, Ülkü Çömelekoğlu, Oya Öğenler Jan 2003

Reversible Conduction Block In Frog Sciatic Nerve For Three Different Concentrations Of Bupivacaine, Belgi̇n Büyükakilli, Ülkü Çömelekoğlu, Oya Öğenler

Turkish Journal of Medical Sciences

We examined the effects of various concentrations of the bupivacaine commonly used for spinal anaesthesia on the reversibility of conduction block in isolated frog sciatic nerves measured by the extracellular recording technique. Seventy-two isolated nerves were divided into 3 groups (n = 24), each of which was bathed in a different bupivacaine solution in a range of concentrations (10, 20 or 30 mM for 20 min). In each group, the extracellular action potentials were recorded before exposure to the bupivacaine solution to provide the control data. The extracellular action potentials were recorded after 20 min exposure to the drug by …


A Novel Method Of Reporting C-Erbb-2 Overexpression; Correlation With Grade But Not With Other Prognostic Parameters In Breast Cancer, Mustafa Samur, Şeyda Karaveli̇, Hakan Bozcuk, Eli̇f Pestereli̇, Mustafa Özdoğan, Mustafa Yildiz, Mehmet Artaç, Burhan Savaş Jan 2003

A Novel Method Of Reporting C-Erbb-2 Overexpression; Correlation With Grade But Not With Other Prognostic Parameters In Breast Cancer, Mustafa Samur, Şeyda Karaveli̇, Hakan Bozcuk, Eli̇f Pestereli̇, Mustafa Özdoğan, Mustafa Yildiz, Mehmet Artaç, Burhan Savaş

Turkish Journal of Medical Sciences

Overexpression of erbB-2 protein is a marker of clinically aggressive behavior in breast cancer patients. In general erbB-2 status is reported on a scale from negative to 3+, depending on staining intensity, if more than 10% of the tumor cells are stained. However, the original definition does not take into account the percentage of stained cells in detail, since all samples score in the same way if they are above the cut-off, established at 10%. In this study, we evaluated the erB-B2 overexpression by immunohistochemistry in 169 patients and evaluated any correlation with the other well known prognostic parameters. We …


The Pathology Of Echinococcosis And The Current Echinococcosis Problem In Western Turkey (A Report Of Pathologic Features In 80 Cases, M. Şerefetti̇n Canda, Meri̇h Güray, Tülay Canda Jan 2003

The Pathology Of Echinococcosis And The Current Echinococcosis Problem In Western Turkey (A Report Of Pathologic Features In 80 Cases, M. Şerefetti̇n Canda, Meri̇h Güray, Tülay Canda

Turkish Journal of Medical Sciences

Echinococcosis is an infection caused by Echinococcus granulosus and E. multilocularis. It manifests as cyst formations in various organs, affecting both humans and animals. The cysts may be unilocular (E. granulosus) or multilocular (E. multilocularis). Multilocular cysts have particular significance, for their macroscopic appearance is reminiscent of malignant tumors and their prognosis is poor. The purpose of this study is to describe our cases and to start a discussion on the current echinococcosis problem in İzmir, western Anatolia. The pathological features of 80 cases of echinococcosis diagnosed at Dokuz Eylül University Pathology Department over the last 21 years have been …


Benign Localized Fibrous Tumor Of The Pleura: Report Of Three Cases And A Review Of The Literature, Ni̇hal Kilinç, Ali̇ Kemal Uzunlar Jan 2003

Benign Localized Fibrous Tumor Of The Pleura: Report Of Three Cases And A Review Of The Literature, Ni̇hal Kilinç, Ali̇ Kemal Uzunlar

Turkish Journal of Medical Sciences

LINÇ, Ali Kemal UZUNLAR Department of Pathology, Faculty of Medicine, Dicle University, Diyarbakır - Turkey


The Serum Levels Of Il-1\Beta, Il-6, Il-8 And Tnf-\Alpha In Nonalcoholic Fatty Liver, İlyas Tuncer, Hanefi̇ Özbek, Cevat Topal, İsmai̇l Uygan Jan 2003

The Serum Levels Of Il-1\Beta, Il-6, Il-8 And Tnf-\Alpha In Nonalcoholic Fatty Liver, İlyas Tuncer, Hanefi̇ Özbek, Cevat Topal, İsmai̇l Uygan

Turkish Journal of Medical Sciences

Nonalcoholic fatty liver (NAFL) has an extensive clinical spectrum ranging from simple fatty liver to steatohepatitis and cirrhosis. Its pathogenesis is multifactorial. The aim of our study was to measure the serum levels of some cytokines (IL-1\beta, IL-6, IL-8 and TNF-\alpha), which are thought to play a role in the pathogenesis of NAFL. Thirty subjects (18 males, 12 females) with clinical and laboratory features of hepatosteatosis were enrolled in the study as the patient group (group 1) and 30 healthy subjects (21 males, 9 females) served as controls (group 2). The levels of hepatic transaminases, gamma-glutamyltransferase, alkaline phosphatase, total cholesterol, …


Determination Of Alkaline Phosphatase Activity In Patients With Different Zinc Metabolic Disorders, Zine Kechrid, Rabah Kenouz Jan 2003

Determination Of Alkaline Phosphatase Activity In Patients With Different Zinc Metabolic Disorders, Zine Kechrid, Rabah Kenouz

Turkish Journal of Medical Sciences

Our purpose was to investigate the effect of different zinc metabolic disorders on alkaline phosphatase activity. Serum zinc, glucose and alkaline phosphatase activity were studied in 32 patients with liver cirrhosis, 30 with chronic renal failure and 42 with insulin-dependent diabetes mellitus (IDDM) compared to 42 healthy volunteers. Serum glucose concentration was significantly higher (P < 0.001) in IDDM and liver cirrhosis patients (P < 0.05) compared to the controls. Serum zinc concentrations tended to be lower in all different diseases but did not reach statistical significance. Alkaline phosphatase activity was higher in IDDM (P < 0.05) and liver cirrhosis patients (P < 0.01) compared with the controls. No positive correlation between serum zinc and alkaline phosphatase activity was recorded in any disease. In conclusion, the investigated diseases did not affect the level of serum zinc; however, there was an alteration in alkaline phosphatase activity in patients suffering from diabetes and liver cirrhosis. Consequently, this may be attributed to the functional disturbance that occurred in these patients. Finally, zinc concentration did not follow alkaline phosphatase activity as indicated by the weak correlation obtained.


Multiple Infected Cerebral Hydatid Cysts Treated With Albendazole, Mehmet Dumlu Aydin, Mustafa Ertek, Hali̇l Yazgi Jan 2003

Multiple Infected Cerebral Hydatid Cysts Treated With Albendazole, Mehmet Dumlu Aydin, Mustafa Ertek, Hali̇l Yazgi

Turkish Journal of Medical Sciences

umlu AYDIN^1, Mustafa ERTEK^2, Halil YAZGI^3 ^1Department of Neurosurgery, Faculty of Medicine, Atatürk University, Erzurum - Turkey ^2Department of Infectious Disease, Faculty of Medicine, Atatürk University, Erzurum - Turkey 3Department of Clinical Microbiology, Faculty of Medicine, Atatürk University, Erzurum - Turkey


Haemophilus Parainfluenzae Endocarditis, Emi̇ne Alp, Orhan Yildiz, Bi̇lgehan Aygen, Bülent Sümerkan Jan 2003

Haemophilus Parainfluenzae Endocarditis, Emi̇ne Alp, Orhan Yildiz, Bi̇lgehan Aygen, Bülent Sümerkan

Turkish Journal of Medical Sciences

No abstract provided.


Acute Adrenal Insufficiency In A 30-Year-Old Woman With Active Pulmonary Tuberculosis, Refi̇k Demi̇rtunç, Meli̇h Başar Jan 2003

Acute Adrenal Insufficiency In A 30-Year-Old Woman With Active Pulmonary Tuberculosis, Refi̇k Demi̇rtunç, Meli̇h Başar

Turkish Journal of Medical Sciences

MİRTUNÇ, Melih BAŞAR Department of Internal Medicine, Haydarpaşa Numune Training and Research Hospital, İstanbul - Turkey


Atophic Rhinitis : A Case Report, Ayli̇n Yücel, Orhan Aktepe, Fatma Aktepe, Fevzi̇ Sefa Dereköy Jan 2003

Atophic Rhinitis : A Case Report, Ayli̇n Yücel, Orhan Aktepe, Fatma Aktepe, Fevzi̇ Sefa Dereköy

Turkish Journal of Medical Sciences

CEL^1, Orhan AKTEPE^2, Fatma AKTEPE^3, Fevzi Sefa DEREKOY^4 ^1Department of Radiology, Faculty of Medicine Afyon Kocatepe University, Afyon - Turkey ^2Department of Microbiology, Faculty of Medicine Afyon Kocatepe University, Afyon - Turkey ^3Department of Pathology, Faculty of Medicine Afyon Kocatepe University, Afyon - Turkey ^4Department of Otolaryngology, Faculty of Medicine Afyon Kocatepe University, Afyon - Turkey


Late Onset Status Epilepticus As A Sign Of Multiple Sclerosis, Serpi̇l Demi̇rci̇, Nezi̇hi̇ Eren Jan 2003

Late Onset Status Epilepticus As A Sign Of Multiple Sclerosis, Serpi̇l Demi̇rci̇, Nezi̇hi̇ Eren

Turkish Journal of Medical Sciences

EMİRCİ Süleyman Demirel University, School of Medicine Neurology Department, Isparta - Turkey Nezihi EREN Denizli Government Hospital, Neurology Department, Denizli - Turkey


Effect Of Edta On The Susceptibility Of Pseudomonas Aeruginosa To Imipenem, Ceftazidime And Cefepime In Mueller-Hinton Agar, Nezahat Akpolat, Tuncer Özeki̇nci̇, Gülseren Aktar, Özge Karaşahi̇n, Adnan Suay Jan 2003

Effect Of Edta On The Susceptibility Of Pseudomonas Aeruginosa To Imipenem, Ceftazidime And Cefepime In Mueller-Hinton Agar, Nezahat Akpolat, Tuncer Özeki̇nci̇, Gülseren Aktar, Özge Karaşahi̇n, Adnan Suay

Turkish Journal of Medical Sciences

No abstract provided.