Medicine and Health Sciences Commons^™

Greater Strength Gains After Training With Accentuated Eccentric Than Traditional Isoinertial Loads In Already Strength-Trained Men, Simon Walker, Anthony J. Blazevich, Greg Haff, James J. Tufano, Robert Newton, Keijo Häkkinen

Research outputs 2014 to 2021

As training experience increases it becomes more challenging to induce further neuromuscular adaptation. Consequently, strength trainers seek alternative training methods in order to further increase strength and muscle mass. One method is to utilize accentuated eccentric loading, which applies a greater external load during the eccentric phase of the lift as compared to the concentric phase. Based upon this practice, the purpose of this study was to determine the effects of 10 weeks of accentuated eccentric loading vs. traditional isoinertial resistance training in strength-trained men. Young (22 ± 3 years, 177 ± 6 cm, 76 ± 10 kg, n = …

A Meta-Analytic Review Of The Efficacy Of Physical Exercise Interventions On Cognition In Individuals With Autism Spectrum Disorder And Adhd, Wei Z. Tan, Julie Ann Pooley, Craig P. Speelman

Research outputs 2014 to 2021

This review evaluates the efficacy of using physical exercise interventions on improving cognitive functions in individuals with autism spectrum disorder (ASD) and/or attention deficit hyperactivity disorder (ADHD). This review includes a meta-analysis based on a random-effects model of data reported in 22 studies with 579 participants aged 3–25 year old. The results revealed an overall small to medium effect of exercise on cognition, supporting the efficacy of exercise interventions in enhancing certain aspects of cognitive performance in individuals with ASD and/or ADHD. Specifically, similar to the general population literature, the cognitive benefits of exercise are not consistent across all aspects …

Iron Supplementation And Altitude: Decision Making Using A Regression Tree, Laura A. Garvican-Lewis, Andrew D. Govus, Peter Peeling, Chris R. Abbiss, Christopher J. Gore

Research outputs 2014 to 2021

No abstract provided.

Aβ-Related Memory Decline In Apoe Ε4 Noncarriers: Implications For Alzheimer Disease, Yen Ying Lim, Simon Laws, Victor Villemagne, Robert Pietrzak, Tenielle Porter, David Ames, Christoher Fowler, Stephanie Rainey-Smith, Peter Snyder, Ralph Martins, Olivier Salvado, Pierrick Bourgeat, Christopher Rowe, Colin Masters, Paul Maruff

Research outputs 2014 to 2021

Objective:

As the absence of Aβ-related memory decline in APOE ϵ4 noncarriers may be due to the relative brevity of previous studies, we aimed to characterize Aβ-related cognitive decline over 72 months in APOE ϵ4 carriers and noncarriers who were cognitively normal (CN).

Methods:

CN older adults (n 423) underwent Aβ imaging and APOE genotyping. Participants completed comprehensive neuropsychological testing at baseline 18-, 36-, 54-, and 72-month assessments.

Results:

Relative to Aβ- CN ϵ4 noncarriers, both Aβ+ CN ϵ4 carriers and noncarriers showed significantly increased decline in measures of memory, language, and executive function as well as higher rates of …

Motor Subtype As A Predictor Of Future Working Memory Performance In Idiopathic Parkinson's Disease, Andrew R. Johnson, Romola S. Bucks, Robert T. Kane, Meghan G. Thomas, Natalie Gasson, Andrea M. Loftus

Research outputs 2014 to 2021

Parkinson’s disease is a progressive neurodegenerative disorder associated with reduced spatial and verbal working memory ability. There are two established motor subtypes of PD, tremor dominant (TD) and postural instability and gait difficulty (PIGD). This study used structural equation modelling to explore the longitudinal relationship between the two subtypes and working memory assessed at a 2-year follow-up. The study comprised 84 males and 30 females (N = 114), aged between 39 and 85 (M = 64.82, SD = 9.23) with confirmed PD. There was no significant relationship between motor subtype at Time 1 and working memory at Time 2. Postural …

Impaired Energy Metabolism: Involvement In Neurodegenerative Processes And Cns Ageing, Veer B. Gupta, Vivek K. Gupta

Research outputs 2014 to 2021

World is experiencing a consistent and steady increase in the ageing population with even higher proportional differences in the developed countries. Increase in ageing populations is directly correlated with the increased prevalence of age-related degenerative diseases of the central nervous system (CNS) such as Alzheimer’s disease and various other forms of dementias, stroke, Parkinson’s disease, retinal degenerative disorders, Huntington’s’ disease, multiple sclerosis, psychiatric and behavioural disorders amongst others.

A Randomized Controlled Trial Of Very Early Rehabilitation In Speech After Stroke, Erin Godecke, Elizabeth Armstrong, Tapan Rai, Sandy Middleton, Natalie Ciccone, Anne Whitworth, Miranda Rose, Audrey Holland, Fiona Ellery, Graeme Hankey, Dominique Cadilhac, Julie Bernhardt

Research outputs 2014 to 2021

Rationale:

The efficacy of rehabilitation therapy for aphasia caused by stroke is uncertain.

Aims and hypothesis:

The Very Early Rehabilitation of Speech (VERSE) trial aims to determine if intensive prescribed aphasia therapy (VERSE) is more effective and cost saving than non-prescribed, intensive (usual care-plus) and non-intensive usual care (UC) therapy when started within 15 days of stroke onset and continued daily over four weeks. We hypothesize that aphasia therapy when started very early after stroke and delivered daily could enhance recovery of communication compared with UC.

Sample size estimates:

A total of 246 participants (82 per arm) will provide 80% …

Musculoskeletal Asymmetry In Football Athletes: A Product Of Limb Function Over Time, Nicolas H. Hart, Sophia Nimphius, Jason Weber, Tania Spiteri, Timo Rantalainen, Michael Dobbin, Robert Newton

Research outputs 2014 to 2021

Purpose

Asymmetrical loading patterns are commonplace in football sports. Our aim was to examine the influence of training age and limb function on lower-body musculoskeletal morphology.

Methods

Fifty-five elite football athletes were stratified into less experienced ( ≤ 3 yr; n = 27) and more experienced ( > 3 yr; n = 28) groups by training age. All athletes underwent whole-body dual-energy x-ray absorptiometry scans and lower-body peripheral quantitative computed tomography tibial scans on the kicking and support limbs.

Results

Significant interactions between training age and limb function were evident across all skeletal parameters (F16, 91 = 0.182, P = 0.031, …

Drug Therapy For Obesity With Anti-Aging Genes Modification, Ian J. Martins

Research outputs 2014 to 2021

Nutritional regulation and drug therapy has been the focus of the current obesity epidemic in various countries in the world. Epigenetics is the major mechanism for the development of insulin resistance and obesity with unhealthy diets, oxidative stress and environmental factors relevant to alterations in gene expression with effects on mitochondrial biogenesis, adipose tissue lipid metabolism and energy expenditure. Anti-aging genes are involved in the regulation of adipogenesis with increased sensitivity to anti-aging gene dysfunction associated with adipocyte-neuron interactions compared to other cells. Unhealthy diets downregulate adipocyte anti-aging genes associated with the development of Non Alcoholic Fatty Liver Disease (NAFLD) …

Molecular Determinants And Interaction Data Of Cyclic Peptide Inhibitor With The Extracellular Domain Of Trkb Receptor, Nitin Chitranshi, Vivek Gupta, Yogita Dheer, Veer Gupta, Roshana Vander Wall, Stuart Graham

Research outputs 2014 to 2021

TrkB is a high affinity receptor for the brain derived neurotrophic factor (BDNF) and its phosphorylation stimulates activation of several intracellular signalling pathways linked to cellular growth, differentiation and maintenance. Identification of various activators and inhibitors of the TrkB receptor and greater understanding their binding mechanisms is critical to elucidate the biochemical and pharmacological pathways and analyse various protein crystallization studies. The data presented here is related to the research article entitled "Brain Derived neurotrophic factor is involved in the regulation of glycogen synthase kinase 3β (GSK3β) signalling" [1]. Cyclotraxin B (CTXB) is a disulphide bridge linked cyclic peptide molecule …

Stick Or Switch: A Selection Heuristic Predicts When People Take The Perspective Of Others Or Communicate Egocentrically, Shane Rogers, Nicholas Fay

Research outputs 2014 to 2021

This paper examines a cognitive mechanism that drives perspective-taking and egocentrism in interpersonal communication. Using a conceptual referential communication task, in which participants describe a range of abstract geometric shapes, Experiment 1 shows that perspective-taking and egocentric communication are frequent communication strategies. Experiment 2 tests a selection heuristic account of perspective-taking and egocentric communication. It uses participants' shape description ratings to predict their communication strategy. Participants' communication strategy was predicted by how informative they perceived the different shape descriptions to be. When participants' personal shape description was perceived to be more informative than their addressee's shape description, there was a …

Nursing Education In China: Meeting The Global Demand For Quality Healthcare, Carol Wang, Lisa Whitehead, Sara J. Bayes

Research outputs 2014 to 2021

With a predicted global nursing shortage, ensuring the provision of quality healthcare has become a pressing concern. In China, these concerns include the need to produce nurses trained to a level to support advancing nursing practice and a healthcare system that supports the growth and retention of nurses in China. This paper argues that the standard of nursing education in China plays a crucial role in preparing graduates to meet the health demands of China's growing population and the role that China can play into the future in the global progression of nursing. Collaboration between nursing authorities, educators, and legislators …

X-Ray Protection, Surface Chemistry And Rheology Of Ball-Milled Submicron Gd2o3 Aqueous Suspension, Ly B. T. La, Yee-Kwong Leong, Christopher Leatherday, Pek I. Au, Kevin Hayward, Laichang Zhang

Research outputs 2014 to 2021

X-ray protective garments are typically comprised of lead-based materials, which are toxic to both people and the environment. Developing alternative lightweight radiation shielding materials is a priority for protecting people working with radiation. Gadolinium, with an electron configuration typical of radiation shielding elements, is proposed as a non-toxic replacement for lead. This study provides new insights into the potential for a gadolinium suspension for replacing lead and proposes an inexpensive and effective preparation method. Submicron gadolinium oxide (Gd₂O₃) was generated using a cost effective ball milling method involving addition of NaCl. Then, the dispersed-flocculated behaviour of …

Setting Research Priorities To Improve Global Newborn Health And Prevent Stillbirths By 2025, Sachiyo Yoshida, Jose Martines, Joy E. Lawn, Stephen Wall, Joao Paulo Souza, Igor Rudan, Simon Cousens, Peter Aaby, Ishag Adam, Ramesh Kant Adhikari, Namasivayam Ambalavanan, Shams El Arifeen, Dhana Raj Aryal, Sk Asiruddin, Abdullah Baqui, Aluisio J.D. Barros, Christine S. Benn, Vineet Bhandari, Shinjini Bhatnagar, Sohinee Bhattacharya, Zulfiqar A. Bhutta, Robert E. Black, Hannah Blencowe, Carl Bose, Justin Brown, Christoph Buehrer, Wally Carlo, Jose Guilherme Cecatti, Po-Yin Cheung, Robert Clark, Tim Colbourn, Agustin Conde-Agudelo, Erica Corbett, Andrew E. Czeizel, Abhik Das, Louise Tina Day, Carolyn Deal, Ashok Deorari, Ugur Dilmen, Mike English, Cyril Engmann, Fabian Esamai, Caroline Fall, Donna M. Ferriero, Peter Gisore, Tabish Hazir, Rosemary D. Higgins, Caroline S.E. Homer, Dewan E. Hoque, Lorentz Irgens, Mohammad T. Islam, Joseph De Graft-Johnson, Martias Alice Joshua, William Keenan, Soofia Khatoon, Helle Kieler, Michael S. Kramer, Eve M. Lackritz, Tina Lavender, Laurensia Lawintono, Richard Luhanga, David Marsh, Douglas Mcmillan, Patrick J. Mcnamara, Ben Willem J. Mol, Elizabeth Molyneux, Gelasius K. Mukasa, Miriam Mutabazi, Luis Carlos Nacul, Margaret Nakakeeto, Indira Narayanan, Bolajoko Olusanya, David Osrin, Vinod Paul, Christian Poets, Uma M. Reddy, Mathuram Santosham, Rubayet Sayed, Natalia E. Schlabritz-Loutsevitch, Nalini Singhal, Mary Alice Smith, Peter G. Smith, Sajid Soofi, Catherine Y. Spong, Shahin Sultana, Antoinette Tshefu, Frank Van Bel, Lauren Vestewig Gray, Peter Waiswa, Wei Wang, Sarah L.A. Williams, Linda Wright, Anita Zaidi, Yanfeng Zhang, Nanbert Zhong, Isabel Zuniga, Rajiv Bahl

Research outputs 2014 to 2021

Background

In 2013, an estimated 2.8 million newborns died and 2.7 million were stillborn. A much greater number suffer from long term impairment associated with preterm birth, intrauterine growth restriction, congenital anomalies, and perinatal or infectious causes. With the approaching deadline for the achievement of the Millennium Development Goals (MDGs) in 2015, there was a need to set the new research priorities on newborns and stillbirth with a focus not only on survival but also on health, growth and development. We therefore carried out a systematic exercise to set newborn health research priorities for 2013–2025.

Methods

We used adapted Child …

Medicine In The Early Twenty-First Century: Paradigm And Anticipation - Epma Position Paper 2016, Olga Golubnitschaja, Babak Baban, Giovanni Boniolo, Wei Wang, Rostyslav Bubnov, Marko Kapalla, Kurt Krapfenbauer, Mahmood S. Mozaffari, Vincenzo Costigliola

Research outputs 2014 to 2021

Challenges of “standardisation” and “individualisation” have always been characteristic for medical services. In terms of individualisation, the best possible individual care is the ethical imperative of medicine, and it is a good right of any patient to receive it. However, in terms of standardisation, all the available treatments are based on guideline recommendations derived from large multi-centre trials with many thousands of patients involved. In the most optimal way, the standardisation and individualisation should go hand-in-hand, in order to identify the right patient treating him/her with the right medication and the right dose at the right time point!

Further, …

Accuracy In Measurement Of Elevation Gain In Road Cycling, Paolo Mensaspa, Eric Haakonssen, Avish Sharma, Brad Clark

Research outputs 2014 to 2021

Purpose

Accurate measures of elevation gain are important for monitoring energy expenditure and physical load. The aim of this study was to determine the accuracy of barometric devices used for measuring elevation gain.

Methods

Observational validation study. Twenty-eight barometric altimeter devices (SRM and Garmin) were used to measure total elevation gain during cycling over three different climbs (length range: 3.2-18.4 km), giving a total of 216 climbs. An online mapping tool (http://www.freemaptools.com/elevation-finder.htm) was used to calculate the criterion measure of total elevation gain. Data were categorised into two weather conditions: dry and wet.

Results

The standard errors of the estimate …

Drug Use Monitoring In Australia: An Expansion Into The Pilbara, Natalie Gately, Suzanne Ellis, Robyn Morris

Research outputs 2014 to 2021

The relationship between alcohol, illicit drugs and offending is complex and dynamic. Substance misuse both nationally and internationally has been found to be prevalent in detained populations (Bennett & Holloway 2007, Pernanen, Cousineau, Brochu & Sun 2002, Sweeney & Payne 2012). With the cost of crime in Australia estimated to be $36 billion per annum (AIC 2009), it is important to establish some of the links that, if addressed, may reduce the level of commissions of crime and increase the wellbeing of Australians.

Improving Access To Primary Care For Aboriginal Babies In Western Australia: Study Protocol For A Randomized Controlled Trial, Dan Mcaullay, Kimberley Mcauley, Rhonda Marriott, Glenn Pearson, Peter Jacoby, Chantal Ferguson, Elizabeth Geelhoed, Juli Coffin, Charmaine Green, Selina Sibosado, Barbara Henry, Dorota Doherty, Karen Edmond

Research outputs 2014 to 2021

Background:

Despite a decade of substantial investments in programs to improve access to primary care for Aboriginal mothers and infants, more than 50 % of Western Australian Aboriginal babies are still not receiving primary and preventative care in the early months of life. Western Australian hospitals now input birth data into the Western Australian electronic clinical management system within 48 hours of birth. However, difficulties have arisen in ensuring that the appropriate primary care providers receive birth notification and clinical information by the time babies are discharged from the hospital. No consistent process exists to ensure that choices about primary …

The Effects Of Latrepirdine On Amyloid-Β Aggregation And Toxicity, Tenielle Porter, Prashant Bharadwaj, David Groth, Adrian Paxman, Simon Laws, Ralph Martins, Guiseppe Verdile

Research outputs 2014 to 2021

Latrepirdine (DimebonTM) has been demonstrated to be a neuroprotective and cognition improving agent in neurodegenerative diseases that feature protein aggregation and deposition, such as Alzheimer's disease (AD). The accumulation of amyloid-β (Aβ) protein aggregates is a key event in the neurodegenerative process in AD. This study explores if latrepirdine modulation of protein aggregation contributes to its neuroprotective mechanism of action. Assessment of neuronal cell death showed that there was a significant reduction in lactate dehydrogenase release at an equimolar ratio of Aβ:latrepirdine and with lower concentrations of latrepirdine. The ability of latrepirdine to alter the formation of Aβ42 aggregates was …

Comparing Biological Markers Of Alzheimer's Disease Across Blood Fraction And Platforms: Comparing Apples To Oranges, Sid E. O'Bryant, Simone Lista, Robert A. Rissman, Melissa Edwards, Fan Zhang, James Hall, Herik Zetterberg, Simon Lovestone, Veer Bular Gupta, Neill Graff-Radford, Ralph N. Martins, Andreas Jeromin, Stephen Waring, Esther Oh, Mitchel Kling, Laura D. Baker, Harald Hampel

Research outputs 2014 to 2021

Introduction:

This study investigated the comparability of potential Alzheimer's disease (AD) biomarkers across blood fractions and assay platforms.

Methods:

Nonfasting serum and plasma samples from 300 participants (150 AD patients and 150 controls) were analyzed. Proteomic markers were obtained via electrochemiluminescence or Luminex technology. Comparisons were conducted via Pearson correlations. The relative importance of proteins within an AD diagnostic profile was examined using random forest importance plots.

Results:

On the Meso Scale Discovery multiplex platform, 10 of the 21 markers shared > 50% of the variance across blood fractions (serum amyloid A R2 = 0.99, interleukin (IL)10 R2 = 0.95, fatty …

The Impact Of Adding Assistants In Nursing To Acute Care Hospital Ward Nurse Staffing On Adverse Patient Outcomes: An Analysis Of Administrative Health Data, Diane E. Twigg, Helen Myers, Christine M. Duffield, Judith Dianne Pugh, Lucy Gelder

Research outputs 2014 to 2021

Objectives:

The aim of this study was to assess the impact of adding assistants in nursing to acute care hospital ward nurse staffing on adverse patient outcomes using administrative health data.

Design:

Logistic regression modelling was used with linked administrative health data to examine the association between seven adverse patient outcomes and use of assistants in nursing utilising a pre-test/ post-test design. Outcomes included were in-hospital 30-day mortality, failure to rescue, urinary tract infection, pressure injury, pneumonia, sepsis and falls with injury.

Setting:

Eleven acute care metropolitan hospitals in Western Australia. Sample: Patients were retained in the dataset if they …

China Suboptimal Health Cohort Study: Rationale, Design And Baseline Characteristics, Youxin Wang, Siqi Ge, Yuxiang Yan, Anxin Wang, Zhongyao Zhao, Xinwei Yu, Jing Qui, Mohamed Ali Alzain, Hao Wang, Honghong Fang, Qing Gao, Manshu Song, Jie Zhang, Yong Zhou, Wei Wang

Research outputs 2014 to 2021

Background:

Suboptimal health status (SHS) is a physical state between health and disease, characterized by the perception of health complaints, general weakness, chronic fatigue and low energy levels. SHS is proposed by the ancient concept of traditional Chinese medicine (TCM) from the perspective of preservative, predictive and personalized (precision) medicine. We previously created the suboptimal health status questionnaire 25 (SHSQ-25), a novel instrument to measure SHS, validated in various populations. SHSQ-25 thus affords a window of opportunity for early detection and intervention, contributing to the reduction of chronic disease burdens.

Methods/design:

To investigate the causative effect of SHS in non-communicable …

Expression Of Cell-Surface Marker Abcb5 Causes Characteristic Modifications Of Glucose, Amino Acid And Phospholipid Metabolism In The G3361 Melanoma-Initiating Cell Line, Norbert W. Lutz, Pallavi Banerjee, Brian J. Watson, Jie Ma, Patrick J. Cozzone, Markus H. Frank

Research outputs 2014 to 2021

We present a pilot study aimed at determining the effects of expression of ATP-binding cassette member B5 (ABCB5), a previously described marker for melanoma-initiating cells, on cellular metabolism. Metabolic profiles for two groups of human G3361 melanoma cells were compared, i.e. wildtype melanoma cells with intact ABCB5 expression (ABCB5-WT) and corresponding melanoma cell variants with inhibited ABCB5 expression, through shRNA-mediated gene knockdown (ABCB5-KD). A comprehensive metabolomic analysis was performed by using proton and phosphorus NMR spectroscopy of cell extracts to examine water-soluble metabolites and lipids. Parametric and non-parametric statistical analysis of absolute and relative metabolite levels yielded significant differences for …

Faster Movement Speed Results In Greater Tendon Strain During The Loaded Squat Exercise, Jacob E. Earp, Robert U. Newton, Prue Cormie, Anthony J. Blazevich

Research outputs 2014 to 2021

Introduction:

Tendon dynamics influence movement performance and provide the stimulus for long-term tendon adaptation. As tendon strain increases with load magnitude and decreases with loading rate, changes in movement speed during exercise should influence tendon strain.

Methods:

Ten resistance-trained men [squat one repetition maximum (1RM) to body mass ratio: 1.65 ± 0.12] performed parallel-depth back squat lifts with 60% of 1RM load at three different speeds: slow fixed-tempo (TS: 2-s eccentric, 1-s pause, 2-s concentric), volitional-speed without a pause (VS) and maximum-speed jump (JS). In each condition joint kinetics, quadriceps tendon length (L_T), patellar tendon force (F_{T …}

Does Nurses’ Health Affect Their Intention To Remain In Their Current Position?, Lin Perry, Robyn Gallagher, Christine M. Duffield, David Sibbritt, Jen Bichel-Findlay, Rachel Nicholls

Research outputs 2014 to 2021

Aim:

To investigate and describe nurses’ and midwives’ physical health, rates of symptoms and disease, and to determine if these factors contribute to intention to leave.

Background:

The nursing and midwifery workforce is ageing yet little is known about their physical health or its relationship to intention to leave.

Methods:

An online survey of health and work-related assessments was distributed through the New South Wales Nurses and Midwives Association and professional contacts.

Results:

Nurses and midwives (n = 5041) reported good-very good health overall. With 22.2% intending to leave in the next 12 months, older age, better …

Neuroendocrine And Neurotrophic Signaling In Huntington's Disease: Implications For Pathogenic Mechanisms And Treatment Strategies, Danielle Bartlett, Travis M. Cruickshank, Anthony J. Hannan, Peter R. Eastwood, Alpár S. Lázár, Mel R. Ziman Dr

Research outputs 2014 to 2021

Huntington's disease (HD) is a fatal neurodegenerative disease caused by an extended polyglutamine tract in the huntingtin protein. Circadian, sleep and hypothalamic-pituitary-adrenal (HPA) axis disturbances are observed in HD as early as 15 years before clinical disease onset. Disturbances in these key processes result in increased cortisol and altered melatonin release which may negatively impact on brain-derived neurotrophic factor (BDNF) expression and contribute to documented neuropathological and clinical disease features. This review describes the normal interactions between neurotrophic factors, the HPA-axis and circadian rhythm, as indicated by levels of BDNF, cortisol and melatonin, and the alterations in these intricately balanced …

Using Technology, Bioinformatics And Health Informatics Approaches To Improve Learning Experiences In Optometry Education, Research And Practice, Vivek K. Gupta, Veer B. Gupta

Research outputs 2014 to 2021

Rapid advances in ocular diagnostic approaches and emerging links of pathological changes in the eye with systemic disorders have widened the scope of optometry as the front line of eye health care. Expanding professional requirements stipulate that optometry students get a meticulous training in relevant information and communication technologies (ICT) and various bioinformatics and health informatics software to meet current and future challenges. Greater incorporation of ICT approaches in optometry education can facilitate increased student engagement in shared learning experiences and improve collaborative learning. This, in turn, will enable students to participate in and prepare for the complex real-world situations. …

The Emotional Intelligence Of Registered Nurses Commencing Critical Care Nursing, Yvette Nagel, Amanda Towell, Elzabe Nel, Fiona Foxall

Research outputs 2014 to 2021

Background: Critical care is described as complex, detailed healthcare in a unique, technologically rich environment. Critical care nursing requires a strong knowledge base and exceptional clinical and technological skills to cope in this demanding environment. Many registered nurses (RNs) commencing work in these areas may lack resilience, and because of the stress of the critical care environment, coping mechanisms need to be developed. To prevent burnout and to enable critical care nurses to function holistically, emotional intelligence (EI) is essential in the development of such coping mechanisms.

Objective: The aim of this study was to describe the EI …

Heat Shock Gene Sirtuin 1 Regulates Post-Prandial Lipid Metabolism With Relevance To Nutrition And Appetite Regulation In Diabetes, Ian J. Martins

Research outputs 2014 to 2021

New discoveries in medicine are required to understand the importance of appetite regulation that is associated with the overconsumption of foodin Type 2 and Type 3 diabetes. Food restriction in diabetes is essential to maintain the hepatic metabolism of dietary fat with relevance to defective post-prandial lipid metabolism and to the global non alcoholic fatty liver disease (NAFLD) epidemic [1,2]. Premature brain aging has become important with the development of Type 3 diabetesand Alzheimer’s disease [3] that is associated with repression of the anti-aging gene Sirtuin 1 (Sirt 1) relevant topost-prandial lipid metabolism, amyloid beta metabolism (peptide involved in amyloid …

“... They Think We Are Conversing, So We Don ’ T Care About Them ...” Examining The Causes Of Workplace Violence Against Nurses In Ghana, Isaac Mensah Boafo

Research outputs 2014 to 2021

Background:

This study is part of a larger project aimed at exploring the workplace experiences of nurses working in public general hospitals in Ghana. The current paper explores the causes of workplace violence against nurses in Ghana.

Methods:

Twenty-four semi-structured in-depth interviews were conducted with professional nurses working in five regions of Ghana. They were selected through purposive and participant-to-participant snowball sampling techniques. Data was analysed through thematic analyses.

Results:

The findings of the study suggest that nurses are not (always) passive recipients of violence. Workplace violence can be instigated by either of the parties to the nurse-patient/relative interaction. Nurses’ …