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Research News. Publications, 2016. Volume 2, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar

Publications (2015-)

Publications that appeared during the period July 1 through December 31, 2016

Research News. Grants, 2016. Volume 2, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar

Grants (2015-)

Grants and contracts awarded during July-December 2016

Development Of A Clinical Guideline For Preventing Lower Limb Lymphedema In Patients With Gynecologic Cancer, Shinchan Lee, Chengfeng Lin, Keng Fu Hsu, Yuyun Hsu

Rehabilitation Practice and Science

Background: Women receiving gynecological cancer surgery with lymph node dissection may experience lower limb lymphedema, resulting in physical discomfort and poor quality of life (QOL). Purpose: This study developed and assessed the effectiveness of a clinical guideline for preventing lower limb lymphedema in women with gynecological cancer following surgery. Methods: The guideline was created through the following processes: defining the topic and generating clinical questions by using the PICO process, conducting a systematic literature reviewarticle and evidence appraisal, drafting the clinical guideline for Preventing Lower Limb Lymphedema in Patients with Gynecological Cancer (CGP-3L-in-GC), performing two rounds of Delphi consensus, and …

Using Objective Ultrasonographic Findings And Subjective Self-Reported Measures To Evaluate The Effectiveness Of A Novel Single Intra-Articular Injection Of Hyaluronic Acid For The Treatment Of Knee Osteoarthritis: A Preliminary Report, Shenghui Tuan, Ihsiu Liou, Minhui Li, Yunjeng Tsai, Yinhan Chen, Tinyun Liao, Chialing Hung, Hungya Huang, Shufen Sun

Rehabilitation Practice and Science

Purpose: Osteoarthritis (OA) is the most common musculoskeletal disease worldwide. Knee OA is the most common type of OA and is the main cause of disability in elderly people. Intra-articular (IA) injection of hyaluronic acid (HA) has been widely proven to improve pain, physical function, and quality of life among patients with knee OA. However, most of the previous studies have used low-to-moderate molecular weight (MW) HA and have evaluated the clinical benefits by using subjective self-reported measures. In this study, we evaluated the efficacy of a single IA injection of a novel cross-linked HA (HYAJOINT Plus) through objective ultrasonographic …

A Casereport Of Concomitant Injection Of Botulinum Toxin Type A In Detrusor And External Sphincter For Treatment Of Neurogenic Bladder Dysfunction, Sheng-Wei Zeng, Yu-Hui Huang

Rehabilitation Practice and Science

Patients with spinal cord injury above the sacral level usually have spastic type neurogenic bladder dysfunction (NBD). Spastic NBD is usually manifested with detrusor overactivity and detrusor-external sphincter dyssynergia (DESD). Botulinum toxin type A (BoNT-A) injection has been used in treating spastic NBD for long time. This injection can be performed either on the detrusor (which needs an intermittent catheterization program and a greater decrease in intravesicle pressure) or on the external sphincter (which may cause urinary incontinence and a smaller decrease in intravesicle pressure). Here we present a SCI patient receiving a new injection method involving BoNT-A injection simultaneously …

Occupational Skin Cancer And Precancerous Lesions, Fifinela Raissa, Githa Rahmayunita, Sri Linuwih Menaldi, Dewi Soemarko

Journal of General - Procedural Dermatology and Venereology Indonesia

Occupational skin cancer and precancerous lesions are skin disorders caused by exposure to chemical carcinogens such as polycyclic hydrocarbons and arsenic, or radiation, such as ultraviolet light and ionizing light in the workplace. Annual increase in skin cancer incidence is believed to be related to various factors such as frequent intense sunlight exposure (i.e. at work, recreational activities, and sun-tanning habit), ozone depletion, an increase in number of geriatric population, and an increase of public awareness in skin cancer. The most common occupational skin cancers are basal cell carcinoma, squamous cell carcinoma, and melanoma. Examples of occupational precancerous lesion of …

Vaginal Microbiota In Menopause, Martinus Martinus, Larisa Paramitha Wibawa, Evita Halim Effendi, Shannaz Nadia Yusharyahya, Hanny Nilasari, Wresti Indriatmi

Journal of General - Procedural Dermatology and Venereology Indonesia

The human vagina together with its resident, microbiota, comprise a dynamic ecosystem. Normal microbiota is dominated by Lactobacillus species, and pathogen microbiota such as Gardnerella species and Bacteroides species can occur due to decrease in Lactobacillus domination. Lactobacillus plays an essential role in keeping normal vaginal microbiota in balance. Vaginal microbiota adapts to pH change and hormonal value. Changes in the vaginal microbiota over a woman’s lifespan will influence the colonization of pathogenic microbes. They include changes in child, puberty, reproductive state, menopause, and postmenopause. Estrogen levels change will affect the colonization of pathogenic microbium, leading to genitourinary syndrome of …

Suspected Resistance Of Mdt-Mb In Multibacillary Leprosy Of Hansen's Disease: Two Case Reports, Yudo Irawan, Sri Linuwih Menaldi, Emmy Soedarmi Sd, Melani Marissa, Erika Zoulba

Journal of General - Procedural Dermatology and Venereology Indonesia

Resistance to multidrug therapy (MDT) is one of the complications in the treatment of Hansen’s disease/Morbus Hansen (MH). There are two types of resistancy, which are primary and secondary. MDT-multibacillary (MB) resistance must be suspected when no clinical improvement and the acid-fast bacilli (AFB) index is not reduced after 12 months of therapy. A 28-year-old woman with paresthesia on her face, arms and legs since 2.5 years ago, accompanied by thickening of the right posterior tibial nerve. The AFB examination showed a bacteriological index (BI) of 15/6 and morphological index (MI) of 0.50%. The second case, a 42-year-old man came …

Neural Leprosy: A Case Report, Alida Widiawaty, Emmy Soedarmi Sjamsoe-Daili, Taruli Olivia, Sri Linuwih Menaldi, Melani Marissa, Fitri Octaviana

Journal of General - Procedural Dermatology and Venereology Indonesia

Neural leprosy is characterized by neurological deficit without skin lesions, with a prevalence ranging from 1% to 17.7%. Diagnosis might be difficult and need a multidisciplinary approach. This is a case of axonal type motor and sensory polyradiculoneuropathy of the peripheral facial nerve. A 26-year-old woman was referred from the neurology clinic with facial paralysis, suspected as leprosy. Physical examinations were as follows: no skin lesions, left eye lagophthalmos, thickening of right lateral peroneal and bilateral posterior tibial nerves, sensory impairment, peripheral bilateral facial palsy, and wasting of bilateral distal small muscles of the hands, with normal autonomic function. Nerve …

Recording Somatosensory Evoked Potential Of The Posterior Tibial Nerve With A Subdural Strip During Surgery For Spinal Dysraphism And Tethered Cord Syndrome, Han-Lin Wu, Muh-Lii Liang, Hsin-Hung Chen, Chen-Liang Chou, Tsui-Fen Yang

Rehabilitation Practice and Science

Objective: To investigate the feasibility of a subdural strip, placed just proximal to the surgical field, to record somatosensory evoked potentials (SSEPs) of the posterior tibial nerve (PTN) during detethering surgery for spinal dysraphism and/or tethered cord syndrome (TCS). Method: Twenty three patients (thirteen boys and ten girls; age, 4 months to 15 years) were enrolled in this study. Eleven patients had lipomyelomeningoceles, seven had TCS, two had split cord malformations, one with terminal myelocystocele, one with VACTERL syndrome, and one had a spinal tumor at the T11 to L4 level. Aside from the routine preparation needed for functional mapping …

How Burroughs Plays With The Brain, Or Ritornellos As A Means To Produce Déjà-Vu, Antonio José Bonome

CLCWeb: Comparative Literature and Culture

In his article "How Burroughs Plays with the Brain, or Ritornellos as a Means to Produce Déjà-Vu" Antonio José Bonome discusses how the recurrence and significance of one of William S. Burroughs's most potent refrains, "dim jerky faraway," was inspired by its source text, Paul Bowles's second novel Let It Come Down (1952), where Tangiers-Interzone fuels the unwholesome descent of a US-American expatriate not unlike Bowles or Burroughs himself. "Dim jerky faraway" was used by Burroughs during more than two decades in different contexts, and its textual variations have sparked a mélange of colors, sounds, smells, and feelings oscillating in …

Remembering Time, Jonathan Carey

Capstones

My parents were dressed in their Sunday best, heading to a church revival. I was 12 and still the baby of the family, so staying home alone was out of the question. My grandmother Lillian, who preferred to be called Nana, came to babysit me. She relished a little time away from the doldrums and senior citizen gossip that engulfed the high-rise building where she lived,five minutes from my house in Petersburg, Virginia. That evening, as the sounds of “The Young and the Restless” echoed through the house, I tiptoed downstairs to give Nana a playful scare.

Interprofessional Collaboration With Aphasic Patients: A Survey Based Study On Implementation And Benefits, Emily Foster, Alexa Wagner

Graduate Independent Studies - Communication Sciences and Disorders

Interprofessional practice (IPP), collaboration of professionals from different backgrounds working together to provide services, is of growing importance in speech-language pathology and across other disciplines in the vast health field (WHO, 2010). The American Speech and Hearing Association (ASHA) stresses the importance of communicating roles and responsibilities of health professionals to provide the best quality care for patients (Dixon & Oandasan, 2015). In order to understand the roles and responsibilities across disciplines, health care professionals and students need to be provided with the necessary education. Currently, an initiative for interprofessional competency is being constructed to provide more involved education for …

Perbedaan Tingkat Komitmen Tugas Siswa Kelas Akselerasi Dan Siswa Kelas Reguler Di Sma Negeri Se-Kota Kediri, Rosalia Dewi Nawantara, Laelatul Arofah

Jurnal Kajian Bimbingan dan Konseling

Education plays an important role in shaping the character of students. One of the characters to be instilled by teachers is task commitment. However, what happens in the field, students have lack of responsibility in completing tasks. Task commitment identical with gifted academic children which is acceleration class students. Despite that commitment to duty is basically owned by everyone including regular students. The purpose of this study was to determine level of commitment differences of acceleration class students and regular class students. The method used is descriptive survey research. Data analysis technique used is Mann Whitney test. From the calculation …

Stroke Outreach In The Lao Community, Noor A. Dythavon

Master's Projects and Capstones

CNL Abstract

A community health needs assessment for the service area prompted concern regarding access to quality healthcare for non-English speaking Southeast Asians (SEA) in the area. Goals of an initial investigation and subsequent implementation of sustainable stroke health fairs for non-English speaking communities were evaluated to assess primary healthcare concerns that the SEA community face and to suggest long-term solutions to these issues. Initial investigation required researching population-specific minority health statistics to quantify the prevalence of chronic diseases and conditions which were prioritized in terms of needs versus disparities. Research came from evidence base practice guidelines and personal concern …

Assessment Of Achieved Systolic Blood Pressure In Newly Treated Hypertensive Patients Aged 60-79 Years Before And After Eighth Joint National Committee Recommendations, Michael S. Kelly, Joseph J. Saseen, Joel C. Marrs

Pharmacy Faculty Articles and Research

Objective:

To determine whether patients who were newly prescribed antihypertensive therapy after the Eighth Joint National Committee (JNC 8) update were treated to a relaxed systolic blood pressure (SBP) goal compared with patients treated before the update.

Methods:

A retrospective cohort study approved by the Colorado Multiple Institutional Review Board. Patients aged 60–79 years, without diabetes or chronic kidney disease (CKD), newly treated for hypertension at a University of Colorado primary care clinics were included. The mean first-achieved and last-stable SBPs of patients newly prescribed antihypertensive medications from 1 January 2012 to 31 December 31 2013 (before cohort) were compared …

Pengembangan Media Layanan Informasi Menghadapi Perubahan Masa Pubertas Bagi Siswa Sekolah Dasar, Fitri Firdayati, Ella Faridati Zen, Elia Flurentin

Jurnal Kajian Bimbingan dan Konseling

This research aims to produce a product in the form of information service media "dealing with changes in puberty" for elementary school students. The research method used is research and development adapted from the Borg and Gall development model with the following procedures: (1) planning; (2) product development; (3) product testing; (4) final product revision. Product trial data is analyzed quantitatively and qualitatively. Based on the results of the product trial assessment, it can be concluded that the product is very appropriate, very useful, very easy and very interesting theoretically and practically, so it can be used as a medium …

Keefektifan “Proses Guru” Sebagai Teknik Bimbingan Kelompok Untuk Meningkatkan Kemampuan Pengambilan Keputusan Karier Siswa Smk, Guruh Sukma Hanggara

Jurnal Kajian Bimbingan dan Konseling

Career decision-making abilities are an important part of a student's career development continuum. This research aims to determine the effectiveness of the GURU (Ground, Understand, Revise, Use) process as a group guidance technique to improve vocational school students' career decision-making abilities. The Pretest-Posttest Control Group Design experimental method was used in this research and the subjects were 12 students of SMKN 1 Trenggalek. Data analysis using the Two Independent Sample Test Mann Whitney U, obtained the Asymp value. Sig. (2-tailed) of 0.03 < real level ( /2 = 0.05) and it was concluded that the "GURU Process" as a group guidance technique was effective in improving the career decision making abilities of vocational school students. From these results, the researcher suggests that Counselors/BK Teachers can collaborate the TEACHER process with various other approaches, using it to develop various student potentials by paying attention to their development stages, psychological aspects and intervention content. Future researchers are advised to examine the GURU process with other research designs such as Single-Subject Designs or action research and pay attention to the use and feasibility of the instrument and its validity, as well as applying it to develop various other psychological aspects such as motivation, self-esteem, self-efficacy, critical thinking skills, the ability to think respectfully and so on.

Model Cognitive Stage Experiential (Cse) Dan Kesadaran Dini Kebhinekatunggalikaan Siswa Sd Kelas Rendah, Im Hambali

Jurnal Kajian Bimbingan dan Konseling

This research aims to determine: (1) the proportion of the level of awareness of diversity in the very low category; (2) the proportion of the level of awareness of diversity in the low category; (3) the proportion of the level of awareness of diversity in the medium category; (4) the proportion of the level of awareness of diversity in the high category; (5) the proportion of the level of awareness of diversity in the very high category. The research results show that: (1) the proportion of the level of awareness of diversity in the very low category is 42.5%, 43% …

Hubungan Antara Tayangan Erotika Di Pornomedia Terhadap Perilaku Seksual Siswa, Zunita Nur Cahyani, Carolina Ligya Radjah, Blasius Boli Lasan

Jurnal Kajian Bimbingan dan Konseling

The mass media which contain of erotic impression can stimulate teenagers who want to know everything about sexual and want to imitate what they hear and look from mass media as a part of learning process.The purpose of this research is to determine the relationship between the erotical exposure on pornmedia to the sexual behaviour of students. The research design is descriptive correlational on subjects totalling 87 people. The instruments used is the scale of the erotical exposure and sexual behaviour scale which contain 46 items on each scale. Trials carried out to 40 people with the validity 0,312 and …

Influence Of Maternal Breast Milk Ingestion On Acquisition Of The Intestinal Microbiome In Preterm Infants, Katherine E Gregory, Buck S Samuel, Pearl Houghteling, Guru Shan, Frederick M Ausubel, Ruslan I Sadreyev, W Allan Walker

Faculty, Staff and Students Publications

BACKGROUND: The initial acquisition and early development of the intestinal microbiome during infancy are important to human health across the lifespan. Mode of birth, antibiotic administration, environment of care, and nutrition have all been shown to play a role in the assembly of the intestinal microbiome during early life. For preterm infants, who are disproportionately at risk of inflammatory intestinal disease (i.e., necrotizing enterocolitis), a unique set of clinical factors influence the establishment of the microbiome. The purpose of this study was to establish the influence of nutritional exposures on the intestinal microbiome in a cohort of preterm infants early …

Pengaruh Cara Pengeringan Simplisia Daun Senggani (Melastoma Malabathricum L.) Terhadap Aktivitas Antioksidan Menggunakan Metode Dpph (2,2-Difenil-1-Pikrilhidrazil), Sri Luliana, Nera Umilia Purwanti, Kris Natalia Manihuruk

Pharmaceutical Sciences and Research

Drying is the most important step to keep the compound stability in simplicia. The objective of this research is to know the effect of drying methods on antioxidant activity in Melastoma malabathricum L. The drying methods tested were oven-drying at 40°C, direct sunlight, indirect sunlight, air-drying at ± 25°C and fresh samples as control. Result revealed that the drying methods of simplicia were significant differences for antioxidant activity in Melastoma malabathricum L. (p < 0,05). Drying method that has the highest antioxidant activity was by air-drying at ± 25°C is 54.60 %.

Efektivitas Snedds Ekstrak Kulit Manggis Terhadap Bakteri P. Mirabilis Dan S. Epidermidis Yang Terdapat Pada Ulkus Diabetik, Rafika Sari, Liza Pratiwi, Pratiwi Apridamayanti

Pharmaceutical Sciences and Research

Mangosteen rind possesses the ability to conduct antibacterial activity. Under the development relating to drug delivery system, SNEDDS were known to boost the penetration of active compound. The aim of this research is to compare the effectiveness of the antibacterial activity at both SNEDDS preparation and the ethanol extract of mangosteen rind as the antibacteria against the bacteria that cause diabetic ulcers with the most prevalence whether it was Gram positive or Gram negative bacteria like Proteus mirabilis and Staphylococcus epidermidis. The research started by maceration process with the crude extract as the result continued with the phytochemical screening which …

Perbandingan Efek Larvasida Minyak Atsiri Daun Cengkeh (Syzygium Aromaticum L.) Varietas Zanzibar Dengan Temephos Terhadap Larva Nyamuk Aedes Aegypti, Ridzmullah Wishnu Pamungkas, Neneng Syarifah Syafei, Arto Yuwono Soeroto

Pharmaceutical Sciences and Research

The use of temephos as larvicides in disease prevention Dengue Hemorrhagic Fever (DHF) in Indonesia has been going on for 40 years. Larviciding very long led the resistance to temephos. Cloves, one of native Indonesia plant contains eugenol that are toxic to the insect’s body. This study aims to examine the effectiveness of Zanzibar clove leaf essential oil compared to temephos in killing the larvae of Aedes aegypti. This study uses experimental laboratory research design. The samples are larvae of Aedes aegypti stage III. The mosquito larvae were classified into six groups, each given a clove leaf essential oil with …

Variants In Wfs1 And Other Mendelian Deafness Genes Are Associated With Cisplatin-Associated Ototoxicity, Heather E. Wheeler, Eric R. Gamazon, Robert Frisina, Carlos Perez-Cervantes, Omar El Charif, Brandon Mapes, Sophie D. Fossa, Darren Feldman, Robert Hamilton, David J. Vaughn, Clair Beard, Chunkit Fung, Chiristian Kollmannsberger, Jeri Kim, Taisei Mushiroda, Michiaki Kubo, Shirin Ardeshir-Rouhani-Fard, Lawrence H. Einhorn, Nancy Cox, M. Eileen Dolan, Lois Travis

Bioinformatics Faculty Publications

Cisplatin is one of the most commonly used chemotherapy drugs worldwide and one of the most ototoxic. We sought to identify genetic variants that modulate cisplatin-associated ototoxicity (CAO). Experimental Design: We performed a genome-wide association study (GWAS) of CAO using quantitative audiometry (4-12 kHz) in 511 testicular cancer survivors of European genetic ancestry. We performed polygenic modeling and functional analyses using a variety of publicly available databases. We used an electronic health record cohort to replicate our top mechanistic finding. Results: One SNP, rs62283056, in the first intron of Mendelian deafness gene WFS1 (wolframin ER transmembrane glycoprotein) and an expression …

Pengembangan Paket Pelatihan “Ground, Understand, Revise, Use (Guru)-Karier” Untuk Meningkatkan Efikasi Diri Karier Calon Konselor, Nora Yuniar Setyaputri, Blasius Boli Lasan, Devi Permatasari

Jurnal Kajian Bimbingan dan Konseling

Guidance and Counseling is a system, which includes: problems, objectives, techniques, media and evaluation. A technique in implementing BK services cannot stand alone, therefore it needs to be accommodated by a medium. The function of guidance and counseling media is to expedite the process of implementing the guidance and counseling services. The technique chosen is the GURU Process (Ground, Understand, Revise, Use) while the media chosen is the "GURU-Career" training package. The aim of this research is to produce guidance and counseling media in the form of a "GURU-Career" Training Package that can be accepted theoretically and practically. This research …

Keefektifan Teknik Self Instruction Dalam Konseling Cognitive Behavior Counseling Untuk Meningkatkan Efikasi Diri Sosial Siswa Smkn 2 Malang, Fitri Aryadini Dewi, Adi Atmoko, Triyono Triyono

Jurnal Kajian Bimbingan dan Konseling

This study aims to determine the effectiveness of self instruction technique in cognitive behavior counseling to improve the self efficacy in social relation of vocational students. This experimental study using Single Case Experimental Design (SCED) model of the A-B-A’. The subject of research are three students of SMKN 2 Malang which show a low level of self efficacy social based on the scale of self efficacy social. The research instrument used as scale self efficacy social with the validity > 0.3 and reliability 0, 883, observation guidelines, and counseling guidelines. The results showed that subjects experienced an increase in social self-efficacy …

Uji Aktivitas Anti-Inflamasi Minyak Atsiri Daun Kemangi (Ocimum Americanum L.) Pada Tikus Putih Jantan Yang Diinduksi Karagenan, Fadlina Chany Saputri, Rita Zahara

Pharmaceutical Sciences and Research

Kemangi (Ocimum americanum L.) is an aromatic plant that contains citral and known as anti-inflammatory agents. The aim of this study was to determine the anti-inflammatory activity of the essential oil kemangi leaves on carrageenan-induced rat. The male rats were divided into six groups, each consisting of four rats. Group I as negative control was given 0.5% CMC solution, group II as positive control was given diclofenac sodium, group III was given sitral, groups IV, V and VI were given 40 mg/200 g BW, 80 mg/200 g BW, and 160 mg/200 g BW essential oil of Ocimum americanum L., emulsified …

The Determinants Of Health: Neighborhood Characteristics, Obesity And The Mental Health Of African-American Adolescent Girls, Roseanne L. Flores

Publications and Research

The present study examined the relationship among neighborhood characteristics, obesity, and the mental health outcomes of a nationally representative sample of African-American adolescent girls between the ages of 12 - 17. Using data from the 2011/2012 National Survey of Children’s Health, four questions were extracted to measure neighborhood amenities, neighborhood detractors, body mass index, and experience of depression. Ordinal regressions were calculated to estimate the relationships between all variables. The results indicated that over 25% of African- American girls, ages 12 - 14 were overweight and obese with fewer 15 - 17-year-old girls falling within these categories. African-American girls had …

Perbandingan Klaim Penyakit Katastropik Peserta Jaminan Kesehatan Nasional Di Provinsi Dki Jakarta Dan Nusa Tenggara Timur, Heniwati Heniwati, Hasbullah Thabrany

Jurnal Ekonomi Kesehatan Indonesia

Several diseases that become catastrophic at the household level include end-stage renal disease, cardiovascular diseases, cancer, thalassemia, and hemophilia. Patients with these diseases benefit significantly from the National Health Insurance (JKN), and these conditions absorb high claim costs from JKN. Special attention is needed to manage these diseases effectively. Disparities in healthcare facilities, specialists, and variations in Case Mix Group (CMG) payment are suspected to be important contributing factors to the variation in JKN fund absorption across provinces. This study uses 2014 claim data from BPJS Kesehatan in Jakarta and East Nusa Tenggara (NTT) provinces to explore the extent of …