Medicine and Health Sciences Commons^™

Segmental Musculoskeletal Examinations Using Dual-Energy X-Ray Absorptiometry (Dxa): Positioning And Analysis Considerations, Nicolas H. Hart, Sophia Nimphius, Tania Spiteri, Jodie L. Cochrane, Robert U. Newton

Research outputs 2014 to 2021

Musculoskeletal examinations provide informative and valuable quantitative insight into muscle and bone health. DXA is one mainstream tool used to accurately and reliably determine body composition components and bone mass characteristics in-vivo. Presently, whole body scan models separate the body into axial and appendicular regions, however there is a need for localised appendicular segmentation models to further examine regions of interest within the upper and lower extremities. Similarly, in-consistencies pertaining to patient positioning exist in the litera-ture which influence measurement precision and analysis out-comes highlighting a need for standardised procedure. This paper provides standardised and reproducible: 1) positioning and analysis …

Effects Of Ambient Coarse, Fine, And Ultrafine Particles And Their Biological Constituents On Systemic Biomarkers: A Controlled Human Exposure Study, Ling Liu, Bruce Urch, Raymond Poon, Mieczyslaw Szyszkowicz, Mary Speck, Diane R. Gold, Amanda J. Wheeler, James A. Scott, Jeffrey R. Brook, Peter S. Thorne, Frances S. Silverman

Research outputs 2014 to 2021

Background: Ambient coarse, fine, and ultrafine particles have been associated with mortality and morbidity. Few studies have compared how various particle size fractions affect systemic biomarkers. Objectives: We examined changes of blood and urinary biomarkers following exposures to three particle sizes. Methods: Fifty healthy nonsmoking volunteers, mean age of 28 years, were exposed to coarse (2.5–10 μm; mean, 213 μg/m3) and fine (0.15–2.5 μm; mean, 238 μg/m3) concentrated ambient particles (CAPs), and filtered ambient and/or medical air. Twenty-five participants were exposed to ultrafine CAP (< 0.3 μm; mean, 136 μg/m3) and filtered medical air. Exposures lasted 130 min, separated by ≥ 2 weeks. Blood/urine samples were collected preexposure and 1 hr and 21 hr postexposure to determine blood interleukin-6 and C-reactive protein (inflammation), endothelin-1 and vascular endothelial growth factor (VEGF; vascular mediators), and malondialdehyde (lipid peroxidation); as well as urinary VEGF, 8-hydroxy-deoxy-guanosine (DNA oxidation), and malondialdehyde. Mixed-model regressions assessed pre- and postexposure differences. results: One hour postexposure, for every 100-μg/m3 increase, coarse CAP was associated with increased blood VEGF (2.41 pg/mL; 95% CI: 0.41, 4.40) in models adjusted for O3, fine CAP with increased urinary malondialdehyde in single- (0.31 nmol/mg creatinine; 95% CI: 0.02, 0.60) and two-pollutant models, and ultrafine CAP with increased urinary 8-hydroxydeoxyguanosine in single- (0.69 ng/mg creatinine; 95% CI: 0.09, 1.29) and two-pollutant models, lasting < 21 hr. Endotoxin was significantly associated with biomarker changes similar to those found with CAPs. conclusions: Ambient particles with various sizes/constituents may influence systemic biomarkers differently. Endotoxin in ambient particles may contribute to vascular mediator changes and oxidative stress.

Pm2.5 Spatiotemporal Variations And The Relationship With Meteorological Factors During 2013-2014 In Beijing, China, Fangfang Huang, Xia Li, Chao Wang, Qin Xu, Wei Wang, Yanxia Luo, Lixin Tao, Qi Gao, Jin Guo, Sipeng Chen, Kai Cao, Long Liu, Ni Gao, Xiangtong Liu, Kun Yang, Aoshuang Yan, Xiuhua Guo

Research outputs 2014 to 2021

Objective: Limited information is available regarding spatiotemporal variations of particles with median aerodynamic diameter < 2.5 μm (PM_2.5) at high resolutions, and their relationships with meteorological factors in Beijing, China. This study aimed to detect spatiotemporal change patterns of PM_2.5 from August 2013 to July 2014 in Beijing, and to assess the relationship between PM_2.5 and meteorological factors. Methods: Daily and hourly PM_2.5 data from the Beijing Environmental Protection Bureau (BJEPB) were analyzed separately. Ordinary kriging (OK) interpolation, time-series graphs, Spearman correlation coefficient and coefficient of divergence (COD) were used to describe the spatiotemporal variations of PM_2.5. …

Association Between Ideal Cardiovascular Health Metrics And Depression In Chinese Population : A Cross-Sectional Study, Zhikun Li, Xin Yang, Anxin Wan, Jing Qui, Wei Wang, Qiaofeng Song, Xizhu Wang

Research outputs 2014 to 2021

The study aimed to examine the association between ideal cardiovascular health (CVH) metrics and depression. We conducted a population-based, cross-sectional study of 6,851 participants aged 20 years or older (3,525 men and 3,326 women) living in Tangshan City, China. Information on the seven CVH metrics (including smoking, body mass index, dietary intake, physical activity, blood pressure, total cholesterol and fasting blood glucose) was collected via questionnaires, physical examination and laboratory test. Depression status was assessed using the Epidemiologic Studies Depression Scale (CES-D) and a score of 16 or above was considered depression. The relationship between CVH metrics and depression was …

Impact Of Altitude On Power Output During Cycling Stage Racing, Laura A. Garvican-Lewis, Bradley Clark, David T. Martin, Yorck O. Schumacher, Warren Mcdonald, Brian Stephens, Fuhai Ma, Kevin G. Thompson, Christopher J. Gore, Paolo Mensaspa

Research outputs 2014 to 2021

Purpose The purpose of this study was to quantify the effects of moderate-high altitude on power output, cadence, speed and heart rate during a multi-day cycling tour. Methods Power output, heart rate, speed and cadence were collected from elite male road cyclists during maximal efforts of 5, 15, 30, 60, 240 and 600 s. The efforts were completed in a laboratory power-profile assessment, and spontaneously during a cycling race simulation near sea-level and an international cycling race at moderate-high altitude. Matched data from the laboratory power-profile and the highest maximal mean power output (MMP) and corresponding speed and heart rate …

The Partnering With Patients Model Of Nursing Interventions : A First Step To A Practice Theory, Wendy Moyle, Claire M. Rickard, Suzanne K. Chambers, Wendy Chaboyer

Research outputs 2014 to 2021

The development of a body of knowledge, gained through research and theory building, is one hallmark of a profession. This paper presents the “Partnering with Patients Model of Nursing Interventions”, providing direction towards how complex nursing interventions can be developed, tested and subsequently adopted into practice. Coalescence of understanding of patient-centred care, the capabilities approach and the concept of complex healthcare interventions led to the development of the model assumptions and concepts. Application of the model to clinical practice is described, including presentation of a case study, and areas for future research including understanding both patients’ and nurses’ perceptions and …

The Relationship Between The Halosperm Assay And Semen Analysis Performed According To The 4th And 5th Editions Of The World Health Organization Guidelines, Ashleigh Mcevoy, Peter Roberts, Kailin Yap, Phillip L. Matson

Research outputs 2014 to 2021

Background: As a standard reference to evaluate male factor infertility, the majority of fertility laboratories use the 4th or 5th Editions of the World Health Organization’s semen analysis guidelines. Following the release of the 5th Edition, debate over its legitimacy has resulted in some laboratories using the 4th and others the 5th Edition. DNA integrity tests have been shown to be a valuable adjunct to semen analysis and have subsequently been adopted by many fertility laboratories. This study explored the prevalence of samples with high DNA fragmentation levels according to semen analysis categories using both the 4th and the 5th …

Munchausen By Internet And Nursing Practice : An Ethnonetnographic Case Study, Cynthia Witney, Joyce M. Hendricks Phd, Vicki C. Cope Ms

Research outputs 2014 to 2021

This paper used Feldman’s clues to factitious illness behavior on the Internet (FIBI), to determine whether the online behaviour of one member of an online breast cancer support community www. breastcancerclick.com , moderated by a specialist breast cancer nurse (SBCN), could be Munchausen by Internet (MBI) and why identification of this behaviour is important for online nursing practice. This was a focused ethnonetnographic and qualitative research study whereby the online behaviour of one member was observed and compared with Feldman’s clues to factitious behaviour on the Internet. The online data showed that nine out of ten of Feldman’s clues were …

Relationships Between Lower-Body Muscle Structure And, Lower-Body Strength, Explosiveness And Eccentric Leg Stiffness In Adolescent Athletes, Josh L. Secombe, Sophia Nimphius, Oliver R. Farley, Lina Lundgren, Tai T. Tran, Jeremy M. Sheppard

Research outputs 2014 to 2021

The purpose of the present study was to determine whether any relationships were present between lower-body muscle structure and, lower-body strength, variables measured during a counter-movement jump (CMJ) and squat jump (SJ), and eccentric leg stiffness, in adolescent athletes. Thirty junior male (n = 23) and female (n = 7) surfing athletes (14.8 ± 1.7 y; 1.63 ± 0.09 m; 54.8 ± 12.1 kg) undertook lower-body muscle structure assessment with ultrasonography and performed a; CMJ, SJ and an isomet-ric mid-thigh pull (IMTP). In addition, eccentric leg stiffness was calculated from variables of the CMJ and IMTP. Moderate to very large …

Overview Of Aboriginal And Torres Strait Islander Health Status, 2015, Burns Jane, Samantha Burrow, Neil M. Drew, Michelle Elwell, Caitlin A. Gray, Millie Harford-Mills, Joanne Hoareau, Renee Lynch, Andrea Macrae, Trish O'Hara, Christine Potter, Miranda Poynton, Kathy Ride, Avinna Trzesinski

Research outputs 2014 to 2021

The main purpose of the Overview is to provide a comprehensive summary of the most recent indicators of the health and current health status of Australia’s Aboriginal and Torres Strait Islanders people. It has been prepared by Australian Indigenous HealthInfoNet staff as part of our contribution to supporting those who work in the Aboriginal and Torres Strait Islander health sector. The Overview is a key element of the HealthInfoNet commitment to authentic and engaged knowledge development and exchange. The initial sections of this Overview provide information about the context of Aboriginal and Torres Strait Islander health, population, and various measures …

The Canadian Healthy Infant Longitudinal Development (Child) Birth Cohort Study: Assessment Of Environmental Exposures, Tim K. Takaro, James A. Scott, Ryan W. Allen, Sonia S. Anand, Allan B. Becker, A. Dean Befus, Michael Brauer, Joanne Duncan, Diana L. Lefebvre, Wendy Lou, Piush J. Mandhane, Kathleen E. Mclean, Gregory Miller, Hind Sbihi, Huan Shu, Padmaja Subbarao, Stuart E. Turvey, Amanda J. Wheeler, Leilei Zeng, Malcolm R. Sears, Jeffrey R. Brook

Research outputs 2014 to 2021

The Canadian Healthy Infant Longitudinal Development birth cohort was designed to elucidate interactions between environment and genetics underlying development of asthma and allergy. Over 3600 pregnant mothers were recruited from the general population in four provinces with diverse environments. The child is followed to age 5 years, with prospective characterization of diverse exposures during this critical period. Key exposure domains include indoor and outdoor air pollutants, inhalation, ingestion and dermal uptake of chemicals, mold, dampness, biological allergens, pets and pests, housing structure, and living behavior, together with infections, nutrition, psychosocial environment, and medications. Assessments of early life exposures are focused …

Estimation Of Bias With The Single-Zone Assumption In Measurement Of Residential Air Exchange Using The Perfluorocarbon Tracer Gas Method, K Van Ryswyk, L. Wallace, D. Fugler, M. Macneill, M. E. Heroux, M. D. Gibson, J. R. Guernsey, W. Kindzierski, A. J. Wheeler

Research outputs 2014 to 2021

Residential air exchange rates (AERs) are vital in understanding the temporal and spatial drivers of indoor air quality (IAQ). Several methods to quantify AERs have been used in IAQ research, often with the assumption that the home is a single, well‐mixed air zone. Since 2005, Health Canada has conducted IAQ studies across Canada in which AERs were measured using the perfluorocarbon tracer (PFT) gas method. Emitters and detectors of a single PFT gas were placed on the main floor to estimate a single‐zone AER (AER1z). In three of these studies, a second set of emitters and detectors were deployed in …

Overview Of Australian Indigenous Health Status, 2014, Jane Burns, Samantha Burrow, Neil Drew, Michelle Elwell, Caitlin Gray, Millie Harford-Mills, Joanne Hoareau, Renee Lynch, Andrea Macrae, Trish O'Hara, Christine Potter, Kathy Ride, Avinna Trzesinski

Research outputs 2014 to 2021

The main purpose of the Overview is to provide a comprehensive summary of the most recent indicators of the health and current health status of Australia’s Aboriginal and Torres Strait Islander peoples. It has been prepared by the Australian Indigenous HealthInfoNet as a part of our contribution to ‘closing the gap’ in health between Aboriginal and Torres Strait Islander people and other Australians by making relevant, high quality knowledge and information easily accessible to policy makers, health service providers, other health professionals including Health workers, program managers, clinicians, researchers, students and the general community.

The initial sections of this Overview …

Overnutrition Determines Lps Regulation Of Mycotoxin Induced Neurotoxicity In Neurodegenerative Diseases, Ian J. Martins

Research outputs 2014 to 2021

Chronic neurodegenerative diseases are now associated with obesity and diabetes and linked to the developing and developed world. Interests in healthy diets have escalated that may prevent neurodegenerative diseases such as Parkinson’s and Alzheimer’s disease. The global metabolic syndrome involves lipoprotein abnormalities and insulin resistance and is the major disorder for induction of neurological disease. The effects of bacterial lipopolysaccharides (LPS) on dyslipidemia and NAFLD indicate that the clearance and metabolism of fungal mycotoxins are linked to hypercholesterolemia and amyloid beta oligomers. LPS and mycotoxins are associated with membrane lipid disturbances with effects on cholesterol interacting proteins, lipoprotein metabolism, and …

The Preparation And Culture Of Washed Human Sperm: A Comparison Of A Suite Of Protein-Free Media With Media Containing Human Serum Albumin, Kelli L. Peirce, Peter Roberts, Jaffar Ali, Phillip Matson

Research outputs 2014 to 2021

Objective

To compare two suites of culture media (one with HSA and one protein-free (PF) supplemented with methylcellulose) for washing human sperm in IVF.

Methods

Semen samples (n = 41) underwent parallel density gradient preparation using PF or HSA-supplemented culture medium and subsequent yield, survival, morphology and motility were compared.

Results

The PF medium resulted in a significantly higher sperm yield (P < 0.0001), but similar sperm morphology (P = 0.822) and 24-h survival (P = 0.11). There was, however, a lower percentage of progressively motile sperm (P < 0.0001) and a higher proportion of sperm demonstrating non-progressive motility (P < 0.0001) in the PF medium when observed on a Makler Chamber, apparently an artefact as a similar sperm motility index was measured using a Sperm Quality Analyser (P = 0.83). Attachment of sperm in PF medium to the glass chamber …

Is There An Economic Case For Investing In Nursing Care – What Does The Literature Tell Us?, Diane E. Twigg, Helen Myers, Christine Duffield, Margaret Giles, Gemma Evans

Research outputs 2014 to 2021

Aim

To determine the cost effectiveness of increasing nurse staffing or changing the nursing skill mix in adult medical and/or surgical patients?

Background

Research has demonstrated that nurse staffing levels and skill mix are associated with patient outcomes in acute care settings. If increased nurse staffing levels or richer skill mix can be shown to be cost-effective hospitals may be more likely to consider these aspects when making staffing decisions.

Design

A systematic review of the literature on economic evaluations of nurse staffing and patient outcomes was conducted to see whether there is consensus that increasing nursing hours/skill mix is …

Psychological Wellness And Health-Related Stigma: A Pilot Study Of An Acceptance-Focused Cognitive Behavioural Intervention For People With Lung Cancer, Suzanne K. Chambers, B A. Morris, S Clutton, E Foley, L Giles, P Schofield, D O'Connell, J Dunn

Research outputs 2014 to 2021

People with lung cancer experience health-related stigma that is related to poorer psychosocial and quality of life outcomes. The present Phase 1 study applied mixed methods to test the acceptability of an acceptance-focused cognitive behavioural intervention targeting stigma for this patient group. Fourteen lung cancer patients completed a 6-week Psychological Wellness intervention with pre- and post-test outcome measures of psychological and cancer-specific distress, depression, health-related stigma and quality of life. In-depth interviews applying interpretative phenomenological analysis assessed participants' experiences of the intervention. Moderate to large improvements were observed in psychological (ηp 2=0.182) and cancer-specific distress (ηp 2=0.056); depression (ηp 2=0.621); …

Support After Brain Tumor Means Different Things: Family Caregivers' Experiences Of Support And Relationship Changes, T. Ownsworth, E. Goadby, Suzanne K. Chambers

Research outputs 2014 to 2021

Shorter hospital stays and greater emphasis on outpatient care means that family members have the primary responsibility for supporting a person with brain tumor to manage the physical, cognitive, behavioral, and emotional effects of the illness and its treatment. Given the integral role of family caregivers, it is essential to understand their experience of the impact of brain tumor and their own support needs. Accordingly, this qualitative study aimed to investigate family caregivers' experiences of support and relationship changes in the context of brain tumor. In-depth interviews were conducted with 11 family caregivers (8 spouse/partner, 3 parents) of people with …

The Potential Role Of Exercise In Neuro-Oncology, Prue Cormie, A.K. Nowak, Suzanne K. Chambers, Daniel A. Galvao, Robert U. Newton

Research outputs 2014 to 2021

Patients with brain and other central nervous system cancers experience debilitating physical, cognitive, and emotional effects, which significantly compromise quality of life. Few efficacious pharmacological strategies or supportive care interventions exist to ameliorate these sequelae and patients report high levels of unmet needs in these areas. There is strong theoretical rationale to suggest exercise may be an effective intervention to aid in the management of neuro-oncological disorders. Clinical research has established the efficacy of appropriate exercise in counteracting physical impairments such as fatigue and functional decline, cognitive impairment, as well as psychological effects including depression and anxiety. While there is …

Integrating Psychosocial Care Into Neuro-Oncology: Challenges And Strategies, Suzanne K. Chambers, L. Grassi, M.K. Hyde, J. Holland, J. Dunn

Research outputs 2014 to 2021

Approximately 256,000 cases of malignant brain and nervous system cancer were diagnosed worldwide during 2012 and 189,000 deaths, with this burden falling more heavily in the developed world. Problematically, research describing the psychosocial needs of people with brain tumors and their carers and the development and evaluation of intervention models has lagged behind that of more common cancers. This may relate, at least in part, to poor survival outcomes and high morbidity associated with this illness, and stigma about this disease. The evidence base for the benefits of psychosocial care in oncology has supported the production of clinical practice guidelines …

Psychological Distress And Quality Of Life In Lung Cancer: The Role Of Health-Related Stigma, Illness Appraisals And Social Constraints, Suzanne Chambers, P. Baade, P. Youl, J. Aitken, S. Occhipinti, S. Vinod, P.C. Valery, G. Garvey, K.M. Fong, D. Ball, H. Zorbas, J. Dunn, D.L. O'Connell

Research outputs 2014 to 2021

Objective: Health-related stigma is associated with negative psychological and quality of life outcomes in lung cancer patients. This study describes the impact of stigma on lung cancer patients' psychological distress and quality of life and explores the role of social constraints and illness appraisal as mediators of effect. Methods: A self-administered cross-sectional survey examined psychological distress and quality of life in 151 people (59% response rate) diagnosed with lung cancer from Queensland and New South Wales. Health-related stigma, social constraints and illness appraisals were assessed as predictors of adjustment outcomes. Results: Forty-nine percent of patients reported elevated anxiety; 41% were …

Compliance To Exercise-Oncology Guidelines In Prostate Cancer Survivors And Associations With Psychological Distress, Unmet Supportive Care Needs, And Quality Of Life, Daniel A. Galvao, Robert U. Newton, Robert A. Gardiner, Afaf Grigis, Steven J. Lepore, Anna Stiller, Cathrine Mihalopolous, Steven Occhipinti, Suzanne K. Chambers

Research outputs 2014 to 2021

Objective The purpose of this study was to determine prevalence of Australian prostate cancer survivors meeting contemporary exercise-oncology guidelines and identify associations with distress, unmet supportive care needs, and quality of life. Methods A population-based cohort of 463 prostate cancer survivors who were on 10.8 months post-curative therapy was assessed for compliance with current exercise guidelines for cancer survivors, motivational readiness for physical activity, psychological distress, unmet supportive care needs, and quality of life. Results Only 57 men (12.3%) reported sufficient exercise levels (150 min of moderate intensity or 75 min of strenuous exercise per week and twice weekly resistance …

Assessing The Effectiveness Of Decision Aids For Decision Making In Prostate Cancer Testing: A Systematic Review, Dragan Ilic, Walid Jammal, Pauline Chiarelli, Robert A. Gardiner, Suzanne Hughes, Dana Stefanovic, Suzanne K. Chambers

Research outputs 2014 to 2021

Background Prostate cancer is a leading disease affecting men worldwide. Conflicting evidence within the literature provides little guidance to men contemplating whether or not to be screened for prostate cancer. This systematic review aimed to determine whether decision aids about early detection of prostate cancer improve patient knowledge and decision making about whether to undergo prostate-specific antigen testing. Methods Medline, EMBASE, CINAHL, PsychINFO, Cochrane Database of Systematic Reviews, Database of Abstracts of Reviews of Effects and Health Technology Assessment databases up until March 2014 were searched. All included randomised controlled trials were assessed for methodological quality. Clinical selection and assessment …

Infant Feeding Practices Of Emirati Women In The Rapidly Developing City Of Abu Dhabi, United Arab Emirates, Hazel Gardner, Katherine Green, Andrew Gardner

Research outputs 2014 to 2021

Rapid economic and cultural transition in the United Arab Emirates (UAE) has been accompanied by new challenges to public health; most notably a rapid rise in chronic disease. Breastfeeding is known to improve health outcomes in adulthood, is associated with reduced risk of developing chronic disease, and is therefore an important public health issue for this rapidly increasing population. Factors associated with infant feeding practices were examined in a cohort of 125 Emirati women and their infants, with data collected at birth and 3, 6 and 15 months postpartum by questionnaires and interviews. Participants were recruited in the Corniche Hospital, …

Evaluation Of A Mobile Phone Image-Based Dietary Assessment Method In Adults With Type 2 Diabetes, Megan E. Rollo, Susan Ash, Philipa Lyons-Wall, Anthony W. Russell

Research outputs 2014 to 2021

Image-based dietary records have limited evidence evaluating their performance and use among adults with a chronic disease. This study evaluated the performance of a 3-day mobile phone image-based dietary record, the Nutricam Dietary Assessment Method (NuDAM), in adults with type 2 diabetes mellitus (T2DM). Criterion validity was determined by comparing energy intake (EI) with total energy expenditure (TEE) measured by the doubly-labelled water technique. Relative validity was established by comparison to a weighed food record (WFR). Inter-rater reliability was assessed by comparing estimates of intake from three dietitians. Ten adults (6 males, age: 61.2 ± 6.9 years old, BMI: 31.0 …

Surveys Of Cancer Patients And Cancer Health Care Providers Regarding Complementary Therapy Use, Communication, And Information Needs, Ngaire King, Lynda G. Balneaves, Gregory T. Levin, Thao Nguyen, Jill G. Nation, Cynthia Card, Tracy Truant, Linda E. Carlson

Research outputs 2014 to 2021

Background. Complementary therapies (CTs) are increasingly utilized by cancer patients. Nonetheless, patients report insufficient support from health care practitioners (HCPs) and there is a general lack of patient-practitioner communication about CT use. Best care practices suggest that HCPs should address the needs of patients, including CT use. This study examined current practices of patients and HCPs as well as their interactions relating to CTs. Methods. A total of 481 cancer outpatients and 100 HCPs completed questionnaires. Patient questions addressed CT use and information needs; HCP questions addressed knowledge, opinions and beliefs about complementary and alternative medicine. Patient-practitioner communication around CT …

Evolution Of Testosterone Treatment Over 25 Years: Symptom Responses, Endocrine Profiles And Cardiovascular Changes, Malcolm Carruthers, Paul Cathcart, Mark R. Feneley

Research outputs 2014 to 2021

Introduction: Testosterone treatment has evolved rapidly over the past 25 years as new, more effective and convenient methods have become available. This study reports experience with seven different methods, introduced on the market in the UK. Aim: To establish the symptom response when testosterone treatment was initiated on the basis of clinical features and symptoms of androgen deficiency, and the resulting endocrine, biochemical and physiological responses. Methods: Of 2693 patients attending the 3 Men’s Health Centers – The UK Androgen Study (UKAS), 2247 were treated. Treatments included pellet implants, oral testosterone undecanoate (Testocaps), mesterolone (Proviron), testosterone gel (Testogel), testosterone scrotal …

Galvanic Skin Response In Mood Disorders: A Critical Review, Roisin Vahey, Rodrigo Becerra

Research outputs 2014 to 2021

To critically review the literature on Galvanic Skin Response (GSR) within Mood Disorder populations. GSR profiles were examined for the various types of Mood Disorder and their association with comorbidity, suicidality and predispositions. This review examined studies with emotional and non-emotional stimuli whilst aiming to identify a Mood Disorder GSR profile by comparisons with healthy controls and other psychological or physical disorders. A systematic search for relevant literature was conducted using PsychINFO, CINAHL and MEDLINE databases. Studies using emotional stimuli to measure GSR in mood disorder patients were included. Some studies did not use emotional stimuli, however were included as …

Consanguinity And Pregnancy Outcomes In A Multi-Ethnic, Metropolitan European Population, Rolf Becker, Thomas Keller, Rolf-Dieter Wegner, Heidemarie Neitzel, Markus Stumm, Ute Knoll, Markus Stärk, Heiner Fangerau, Alan Bittles

Research outputs 2014 to 2021

Objective: The aim of the present study was to assess the risk of major anomalies in the offspring of consanguineous couples, including data on the prenatal situation. Methods: Over 20years (1993-2012), 35391 fetuses were examined by prenatal sonography. In 675 cases (1.9%), parents were consanguineous, with 307 couples (45.5%) related as first cousins, 368 couples (54.5%) beyond first cousins. Detailed information was retrieved on 31710 (89.6%) fetuses, (consanguineous 568: 1.8%). Results: Overall prevalence of major anomalies among fetuses with non-consanguineous parents was 2.9% (consanguineous, 10.9%; first cousins, 12.4%; beyond first cousins, 6.5%). Adjusting the overall numbers for cases having been …

Prevalence And Associated Factors Of Myopia In High-School Students In Beijing, Li J. Wu, Qi S. You, Jia L. Duan, Yan X. Luo, Li J. Liu, Xia Li, Qi Gao, Hui P. Zhu, Yan He, Liang Xu, Jost B. Jonas, Wei Wang, Xiu H. Guo

Research outputs 2014 to 2021

Purpose : To evaluate prevalence and associated factors for myopia in high school students in Beijing. Methods : Grade 10 and 11 high school students were randomly selected from nine randomly selected districts of Beijing. The students underwent non-cylcoplegic auto-refractometry and an interview. Results : Out of 4798 eligible students, 4677 (93.4%) students (mean age:16.9±0.7years;range:16–18 years) participated. Mean refractive error of right eyes and left eyes was −2.78±2.29 diopters and −2.59±2.50 diopters, respectively. Prevalence of myopia (defined as ≤ −1.00 diopters in the worse eye) was 80.7% (95% Confidence Interval (CI): 79.6–81.8%). Out of 3773 students with myopia, 1525 (40.4%) …