Medicine and Health Sciences Commons^™

Urinary Oxalate Excretion Is Increased In Calcium Oxalate Nephrolithiasis Patients And Associated With Increased Urinary Capacity Of Calcium Oxalate Crystallization, Chanchai Boonla

Chulalongkorn Medical Journal

Background: Calcium oxalate (CaOx) stone is the most common type of stones formed in the urinary tract. Formation of CaOx stone is driven by increased CaOx crystallization in urine.

Objective: To develop a new test, called indole-reacted calcium oxalate crystallization index (iCOCI), and to measure the capability of urine to produce CaOx crystals.

Methods: One hundred samples of 24-h human urine samples obtained from CaOx stone-forming subjects (SFS, n = 50) and non-stone subjects (NSS, n = 50). The levels of oxalate were determined by two methods, i.e., oxalate oxidase method and iCOCI test. Unpaired student t - test, Pearson’s …

Prevalence Of Preoperative Delirium And Associated Factors In Elderly Hip Fracture Patients At King Chulalongkorn Memorial Hospital, Paul Thisayakorn

Chulalongkorn Medical Journal

Background: Preoperative delirium in hip fracture is under-studied. Effective diagnosis, prevention, and management of preoperative delirium may be able to reduce the incidence of the postoperative complications.

Objective: To study the prevalence of preoperative delirium and its associated factors in elderly patients who underwent hip fracture surgery.

Methods: This is a cross-sectional study which collected the data from patients aged more than 65 years who underwent hip surgery at King Chulalongkorn Memorial Hospital. Preoperative cognitive status assessment was done by using the Thai Mental State Examination (TMSE) and The Confusion Assessment Method-Thai (CAM-T) on the day before surgery. The DSM-V …

The Effectiveness Of A Multimodal Preoperative Anxiety Intervention On Postanesthetic Emergence Delirium In Preschoolers, Thitima Veeraburus

Chulalongkorn Medical Journal

Background: Preoperative anxiety has been reported as one of the major contributors to emergence delirium (ED) in preschoolers.

Objective: This study investigated the effectiveness of multimodal preoperative anxiety intervention (MPreop-AI) in reducing the incidence and severity of ED in preschoolers.

Methods: A prospective study, posttest only nonequivalent groups design, was conducted in 44 children aged 2 - 6 years scheduled for tonsillectomy and/or adenoidectomy under sevoflurane anesthesia. They were equally allocated into two groups. The usual preoperative preparation group (control group) received narrative preoperative education, parental presence, and self-selected toy. The MPreop-AI group received 2-Dimensional (2D) animation modeling-based information, an …

Impostor Phenomenon, Mental Health Status And Coping Strategies Among Medical Students In Southern Thailand, Napakhawarat Buathong

Chulalongkorn Medical Journal

Background: Impostor phenomenon is an internal experience in successful individuals who realize that their achievements are unintended, although their successes can be proven by objective evidence. The study of impostor phenomenon among medical students remains largely unexplored in Thailand, especially during the transitional period from traditional medical training to online training due to the COVID-19 pandemic.

Objectives: To determine the prevalence of impostor phenomenon, mental health and the coping strategies as well as to examine the factors related to impostor phenomenon among Thai medical students.

Methods: Two hundred and seventy-two subjects completed online questionnaires enquiring about sociodemographic characteristics and perception …

Evaluation Of Aspartate Aminotransferase To Platelet Ratio Index And Fibrosis 4 Score For Selecting Patients With Chronic Hepatitis B To Perform Liver Fibrosis Assessment By Transient Elastography In Resource-Limited Areas, Puth Muangpaisarn

Chulalongkorn Medical Journal

Background: Liver stiffness measurement operated by transient elastography (TE) becomes a noninvasive method to assess the severity of hepatic fibrosis. However, TE may not be available in resource-limiting areas. Therefore, simple serum biomarker scoring should be evaluated for fibrotic assessment instead of TE.

Objectives: This study aimed to evaluate the diagnostic performance of aspartate. aminotransferase to platelet ratio index (APRI) and fibrosis-4 (FIB-4) scores compared with TE in chronic hepatitis B (CHB) patients and determine the optimal cut-off values to select the CHB patients who should be referred to higher-level hospital for TE evaluation.

Methods: We conducted a cross-sectional study …

Caffeine Addiction And Mental Health Of Employees In An Organization In Bangkok, Rasmon Kalayasiri

Chulalongkorn Medical Journal

Background: Heavy caffeine consumption is the cause of caffeine addiction that might affect sleep quality and mental health. However, people, especially employees in various companies, may want to gain daily energy for efficient work and productivity by drinking high number of caffeinated beverages such as coffee.

Objectives: To explore coffee consumption, mental health, sleep quality, and factors related to caffeine addiction among employees.

Methods: A total of 321 employees at a company in Bangkok were asked about their demographics, coffee consumption and caffeine addiction by using newly developed instruments, namely Caffeine Addiction Questionnaire. Depression and sleep quality were assessed by …

A Quantitative Enhancement Characterization Of Hyperfunctioning Parathyroid Lesions On Four-Dimensional Ct Scans, Netsiri Dumrongpisutikul

Chulalongkorn Medical Journal

Background: Approximately 20.0% of hyperfunctioning parathyroid lesions do not exhibit typical enhancement characteristics on Four-dimensional computed tomography (4DCT). The two main mimics of hyperfunctioning parathyroid lesions are thyroid tissue and lymph nodes.

Objective: The study aimed to characterize enhancement patterns of hyperfunctioning parathyroid lesions on four-dimensional computed tomography (4DCT) and to differentiate hyperfunctioning parathyroid lesions from thyroid gland and lymph node.

Methods: This retrospective study included analysis of 47 hyperfunctioning parathyroid lesions either pathologically proven or uptake on Tc99m-sestamibi SPECT-CT. The attenuation of hyperfunctioning parathyroid lesions, thyroid glands, lymph nodes and muscles at non-contrast, arterial phase and delayed phase were …

Mental Health, Social Skills, And Associated Factors Of Flight Attendants In A Commercial Airline In Thailand, Thanradee Kongmanee, Peeraphon Lueboonthavatchai

Chulalongkorn Medical Journal

Background: Mounting evidence has shown that most flight attendants have an average mental health and mental health problems such as stress, fatigue, and sleep problems. However, there were limited studies concerning their social skills and associated factors. This study identified the flight attendants’ mental health, associated factors with the mental health of flight attendants in Thai Airways International Public Company Limited. Objective: To explore the mental health, social skills, and associated factors of flight attendants in Thai Airways International Public Company Limited. Methods: A cross-sectional descriptive study was performed with the participation of 408 flight attendants of Thai Airways International …

Workplace Innovation Management Of Nurse Managers In University Hospitals: A Phenomenological Study, Siriwan Thongthip, Kannikar Chatdokmaiprai, Phechnoy Singchungchai

Chulalongkorn Medical Journal

Background: University Hospitals in Thailand still have no responsible unit related to Workplace Innovation Management (WPIM) and First-Line Nurse Managers (FLNMs) are the key person of the organization, but today there is still a lack of knowledge on individual innovation and creativity in the workplace, especially in nursing organizations with the future practice of nursing in a technologically advanced future and keep up with modern society and digital technology transformation era. Objectives: To describe the definition and components of Workplace Innovation Management from First-Line Nurse Managers’ experiences in University Hospitals. Methods: Data were collected by in-depth interviews of FLNMs. Colaizzi’s …

The Coincidence Of Abernethy Malformation And Blue Rubber Bleb Nevus Syndrome: A Case Report, Thipsumon Tangsiwong, Siriwan Wananukul, Panruethai Trinavarat

Chulalongkorn Medical Journal

Abernethy malformation was demonstrated in a 10-year-old boy, whose underlying disease of blue rubber bleb nevus syndrome (BRBNS) was achieved first-time-right diagnosis by cutaneous stigmata, presenting with persistent gross hematuria and hemodynamic instability secondary to vesical venous malformation. Abdominal computed tomography (CT) imaging was obtained to explore identifiable and treatable causes of the active bleeding, revealing Abernathy malformation and unusual visceral slow-flow vascular malformations including venous varicosities and splenic lymphangiomatosis. This is a first case report of the coincidence of Abernathy malformation and BRBNS. Imaging played an important role in detection of clinically occult congenital portal venous anomalies and visceral …

Morphometric Measurements Of Posterior Cranial Fossa And Craniovertebral Junction In Chiari I Malformation With And Without Syringohydromyelia, Pawitra Imemkamon, Supada Prakkamakul, Ketsuda Jakchairoongruang

Chulalongkorn Medical Journal

Background: Syringohydromyelia occurs about 30.0 - 85.0% in patients with Chiari I malformation (CMI). The syrinx formation is supposed to be a result of disturbed cerebrospinal fluid flow dynamics, which is associated with the degree of mechanical blockage that may be related to posterior cranial fossa (PCF) and craniovertebral junction anatomy. Objective: Our study aimed to determine the morphometric difference in PCF and craniocervical junction between the CMI patients with and without syringohydromyelia. Methods: Thirty CMI patients (16 with syringohydromyelia; 14 without syringohydromyelia) and 16 healthy subjects were also recruited. PCF and craniocervical junction measurements of 5 distances and 5 …

Reliability Of The Thai Version Of The Modified Start Back Screening Tool In Individuals With Neck Pain, Nattawan Phungwattanakul, Uchukarn Boonyapo, Taweewat Wiangkham

Chulalongkorn Medical Journal

Backgrounds: The modified STarT Back Screening Tool in Thai version (mSBST-TH) for individuals with neck pain (NP) was adapted from the STarT Back Screening Tool in Thai version (SBST-TH) for individuals with low back pain (LBP) to classify individuals with NP into low, medium, and high risk for chronicity. Owing to a lot of individuals with NP in Thailand. It would be beneficial if the mSBST-TH was available to help primary care management in Thai individuals with NP. However, the reliability of this tool has not been investigated. Objective: The aim of this cross-sectional study was to investigate the reliability …

Acute Effect Of Low-Dose Sugar Ingestion On Forearm Blood Flow In Healthy Men, Manta Korakot, Weerapat Kositanurit, Pachara Varachotisate, Chuti Burana, Chanchai Boonla, Onanong Kulaputana

Chulalongkorn Medical Journal

Background: Hyperglycemia is a major risk factor for cardiovascular disease resulting in vascular damage in both diabetic and non-diabetic people. Objective: To determine acute effect of elevated plasma glucose from a low-dose sugar ingestion on forearm blood flow (FBF) in healthy men. Methods: Ten healthy men (aged 24.1 4.1 years) participated in two experimental conditions: 1) drinking 200 mL of water (Control), and 2) drinking 15 grams of sugar solution (Sugar). The two conditions were scheduled in random order with a minimum of three days of washout period between conditions. FBF was determined by venous occlusion plethysmography. Peak forearm blood …

Cyberbullying, Well-Being And Mental Health Of Freshmen Of A University In Bangkok, Thachira Jamnongrit

Chulalongkorn Medical Journal

Background: Cyberbullying is an electronic harassment commonly found in adolescents and affects the wellbeing and mental health of the victims. Objective: The purpose of this study was to estimate the prevalence of cyberbullying among freshman and to investigate the relationship between cyberbullying, psychological well-being, and mental health among freshmen of Chulalongkorn University. Methods: A cross-sectional design enrolled participation of 1,433 freshmen in 19 faculties of Chulalongkorn University. The subjects were requested to complete online surveys concerning demographic information, cyber-aggression victimization scale (Thai version), Thai mental health questionnaire (TMHQ: CU-modified version), and CU student psychological well-being (revised 2020). Results: Fifty-two point-seven …

Intra-Rater And Inter-Rater Reliability And Minimum Detectable Change Of Visual Analog Scale And Digital Goniometer In Patients With Subacute Unilateral Lateral Ankle Sprain, Thongchai Suksri, Chitanongk Gaogasigam, Sujitra Boonyong

Chulalongkorn Medical Journal

Background: Patients with subacute unilateral lateral ankle sprain commonly experience pain and limited range of motion (ROM). Measurement reliability should be investigated before assessing treatment effectiveness. Objective: To determine both intra-rater and inter-rater reliability and minimal detectable change (MDC) of visual analog scale (VAS) and digital goniometer in patients with subacute unilateral lateral ankle sprain. Methods: Ten subjects (7 men, 3 women; aged 29.90  12.81 years) with subacute unilateral lateral ankle sprain were recruited. Two investigators measured pain intensity and ROM using VAS and a digital goniometer, respectively, with a 30-minute break between measurements. The same protocol was repeated …

Social Media Addiction And Self-Esteem Of High School Students In Hat Yai Municipality, Secondary Educational Service Area Office 16, Thailand, Montira Muanjan, Sookjaroen Tangwongchai

Chulalongkorn Medical Journal

Background: Social media use has been increasing dramatically. Some evidences suggest that excessive use of social media may impact the level of self-esteem. Objective: To explore the level of social media addiction, self-esteem and associated factors among high school students in Hat Yai municipality. Methods: A cross-sectional descriptive design was employed with participation of 415 high school students in Hat Yai municipality. The instruments included a set of questionnaires to assess the demographic data and patterns of social media use, media addiction test (SMAT), Thai version of the Pittsburgh Sleep Quality Index (T-PSQI), Center for Epidemiological Studies-Depression Scale (CES-D) and …

Efficacy Of Digitalized Comprehensive Educational Program For Patients With Allergic Contact Dermatitis: A Randomized Controlled Trial, Wongsiya Viarasilpa, Prattana Sittiwattanawong

Chulalongkorn Medical Journal

Background: Allergic contact dermatitis (ACD) is an inflammatory skin disease resulting from exposure to allergen. The patient education is crucial to successful treatment and management of ACD. However, this process can be time consuming, requiring trained healthcare personnel resulting in increased workload and may be difficult in the setting of limited workforce or resource. Objective: To assess the effect of informative digitalized video-based educational program (iDVE) on patients’ quality of life, disease severity and knowledge of ACD compared to standard counselling (control). Methods: Patients with ACD were randomized to participate in iDVE or control group. The primary outcome was the …

Occupational Stress And Related Factors Among Registered Nurses At Relief And Community Health Bureau, The Thai Red Cross Society, Itsaraporn Palasak, Siriluck Suppapitiporn

Chulalongkorn Medical Journal

Background: Previous studies have found that occupational stress affects work performance among registered nurses and causes a high turnover rate. The study of occupational stress levels and related factors can help prevent occupational stress impacting on physical and mental health. Also, it may help increase work efficiency and enhance the commitment to the organization. Objective: To study the level of occupational stress and related factors among registered nurses at Relief and Community Health Bureau, The Thai Red Cross Society (RCHB-TRC). Methods: This was a cross-sectional study conducted at the RCHB-TRC, Thailand. Data were collected from 133 registered nurses using self-administered …

Development Of A Questionnaire To Evaluate The Attitudes Towards Home Health Visits In Applied Thai Traditional Medical Students: A Pilot Study, Sarunthorn Puttipaibool, Athippat Tantiwongsekunakorn, Kaittiyos Kuldejchaichan, Sukree Kade, Sirikan Poopong, Photnicha Jaturapat, Sasima Tongsai, Suprapath Sonjaipanich, Pravit Akarasereenont

Chulalongkorn Medical Journal

Background: Home health visits (HHV) are the new duty and development of students of applied Thai traditional medicine (ATM). We performed to develop a measuring instrument to ensure that students have positive attitudes to HHV. Objective: To develop a reliable and valid questionnaire for evaluating attitudes regarding home health visits among ATM students. Methods: There are 28 items in creating the questionnaire which is supposed to be used to assess attitudes toward HHV in four areas, including those related to the practice in HHV, the role of ATM practitioners, relationship with patients and patient’s relatives, and collaboration with the multidisciplinary …

Factors Influencing Decision Making To Use Large Private Hospitals Of Thai Patients In Bangkok After Covid-19 Outbreak, Decha Lalitanantpong, Kingporn Thongbai, Anothai Ngamvichaikit

Chulalongkorn Medical Journal

Background: The worldwide pandemic of coronavirus infections disease 2019 (COVID-19 impacts the Thai medical’s hub tourism industry. The private hospital sector needs to provide appropriate services for Thai consumers. Objectives: The objectives of this research were to study: 1) The level of decision making of use large private hospitals of Thai patients living in Bangkok after COVID-19 outbreak; 2) The marketing mix related to the level of decision making to use large private hospitals; 3) The marketing mix that influences decision making to use large private hospitals. Methods: This study was a survey research. The population was 8,757,843 Thai patients …

Changes In Brain Structural Volume And White Matter Abnormalities In Young Perinatally-Acquired Hiv Infected Children Treated With Antiretroviral Therapy, Netsiri Dumrongpisutikul, Kultida Chaiyagool

Chulalongkorn Medical Journal

Background: Several studies have reported human immunodeficiency virus (HIV) effects on brain volume and found white matter signal abnormality (WMSA) on brain magnetic resonance imaging (MRI). Objective: To evaluate brain volume and WMSA of antiretroviral therapy (ART)-treated perinatally-acquired HIV infected (PHIV) young children. Methods: From November 2016 to March 2018, MRI of 19 ART-treated PHIV young children, aged 12 - 56 months, were analyzed for structural brain volume using FreeSurfer software with manual correction. WMSA were classified into 4 grades. Comparison between the brain volumes and WMSA between early and late ART-treated groups as well as changes of the brain …

Marital Satisfaction In Patients With Breast Cancer Who Have Undergone Mastectomy At King Chulalongkorn Memorial Hospital, Chatchadaporn Pornleegalearn, Chutima Roomruangwong

Chulalongkorn Medical Journal

Background: Breast is an organ that affects sexual symbol and sexual satisfaction. The patients with mastectomy may suffer from both physical and psychological effects. The reaction from their close relatives can lead negative effects to the patients, especially, in term of body image. Previous studies in Thailand focused on depression, body image, coping style, and quality of life in breast cancer patients who had undergone mastectomy. However, there are few studies on marital satisfaction and sexual satisfaction. Objectives: To investigate marital satisfaction and related factors in breast cancer patients who had undergone mastectomy at King Chulalongkorn Memorial Hospital. Methods: A …

Cranial Thickness In Relation To Age, Gender And Head Circumference In Thai Population, Sumas Ruenhuns, Vijarn Vachirawongsakorn

Chulalongkorn Medical Journal

Background: The skull is one of the most studied materials of the human bone. To date, several studies have investigated the range of cranial vault thickness variation in modern human. Objective: To investigate the average thickness of cranial vaults in different positions and their relation to individual variables in the Thai population. Methods: Cranial vaults of 118 male and 59 female cadavers aged over 20 years were eligible for the study. The measurement of the cranial vault was conducted as described: frontal cranial thickness (FCT), occipital cranial thickness (OCT), left and right lateral cranial thickness (LCT). The relationship between the …

Depression In Male Patients With Schizophrenia Residing In Half-Way House For Protection And Development Of Mental Disabilities, Pathum Thani Province, Soraya Nabun, Chavit Tunvirachaisakul

Chulalongkorn Medical Journal

Background: Schizophrenia is a mental disorder with prominently impaired cognitive ability and daily life functioning, resulting in institutionalization for some patients A common comorbidity of patients with schizophrenia is depression that could further reduce patients quality of life. Objectives: The current study aimed to examine the prevalence of depression and associated factors in male patients with schizophrenia residing at Half-way House for Protection and Development of Mental Disabilities, Pathum Thani Province. Methods: This cross-sectional descriptive study was conducted among patients with schizophrenia who was residing at the half-way house. The data collection period for all eligible patients was from September …

Incidence And Imaging Pattern Of Stroke After Cardiac Surgery, Saruda Vichitpunt, Netsiri Dumrongpisutikul

Chulalongkorn Medical Journal

Background: Few cases of patients of previous studies have provided information on imaging patterns of stroke after cardiac surgery. Objective: The purpose of this study was to determine the incidence and imaging pattern of stroke after cardiac surgery according to type of cardiac surgery. Methods: A retrospective observational study was conducted on 3,645 adult patients who underwent cardiac surgery in cardiovascular thoracic unit at our institute from January 1, 2010 – September 30, 2019. Cases of patients who were suspected of having post-operative stroke and on whom brain imaging had been performed were reviewed. The ischemic stroke was categorized into …

Parents’ Knowledge And Attitudes Toward Usage Of Digital Screen Devices In 6-Month-Old To 5-Year-Old Children In Thailand, Wiwat Angkittisawat, Napakkawat Buathong, Pantri Kirdchok

Chulalongkorn Medical Journal

Background: Because 6-month-old to 5-year-old children cannot control their behavior of using digital screen devices on their own and control and supervision from parents are required, parents’ knowledge toward proper usage of digital screen devices in children is necessary. Objective: This study aimed to investigate parents’ knowledge and attitudes toward usage of digital screen devices in 6-month-old to 5-year-old children in Thailand. Methods: This was a cross-sectional descriptive study. The data were collected from 954 samples of parents of 6-month-old to 5-year-old children in Thailand. They volunteered to answer the online questionnaire between April – June 2019. Results: Most parents …

A Comparison Of Dilatation Of The Right Atrium On Post Mortem Ct Between Asphyxial Death And Non-Asphyxial Death, Irada Jhunthasiriyakorn, Koravik Meesilpavikkai, Udomsak Hoonvijit, Rathachai Kaewlai, Raksachai Nathongchai

Chulalongkorn Medical Journal

Background: The dilatation of the right atrium and the great vein is one of classical Sign of asphyxial death. The diagnosis of dilatation of the right atrium from the autopsy is difficult due to the unclear criteria and unavailability of measuring the organ size while it is still in the body. Post-mortem computed tomography (PMCT) is useful for the study on the dilatation of the right atrium before autopsy. Objective: This study aimed to compare the size of right atrium measuring with PMCT between the asphyxial and non-asphyxial death. Methods: The samples of this observational analytic research were a total …

Meaning Of Life And Its Association With Perspective Towards Life And Way Of Living: A Qualitative Study In Palliative Care Professionals, Soonthorn Limluck, Wiraporn Pothisiri, Teerayuth Rungnirundorn

Chulalongkorn Medical Journal

Background: Having the meaning of life plays an essential part in human life. It is shown to affect one’s perspective towards life and way of living, and is positively correlated with physical and mental health status. However, the meaning of life in palliative care staff was not yet explored. Objectives: This study aimed to uncover the meaning of life among the palliative care professionals, and to determine factors contributing to the meanings. The associations between the meaning of life and their professions and the way of life were also studied. Methods: Qualitative descriptive method was employed. Twelve palliative care professionals …

Surgical Perspectives Of Primary Liver Tumors In Children: A Series Of 76 Consecutive Cases, Pailin Arunsopha, Kanokrat Thaiwatcharamas, Sinobol Chusilp, Patchareeporn Tanming, Pongserath Sirichindakul, Nimmita Srisan, Katawaetee Decharun, Soottiporn Chittmittrapap, Paisarn Vejchapipat

Chulalongkorn Medical Journal

Background: Primary liver tumors in children are rare. The objective of this study was to review cases of primary liver tumors in children who underwent tumor removal. Methods: Children (0 - 15 years old) who underwent surgery for primary liver tumors between 2006 and 2019 were studied. Their clinical data and pathological reports were reviewed. Demographic data, types of procedures, operative time, and post-operative complications were described. Data are expressed as mean  standard deviation. Results: There were 76 children (male/female = 39/37), who underwent resection for primary liver tumors. Their average age was 27.9  32.0 months. Asymptomatic abdominal …

Antioxidative Properties Of Common Ready-To-Eat Cooked Foods And Beverages In Thailand, Kamonchanok Chuenwisad, Nattida Chotechuang, Chanchai Boonla

Chulalongkorn Medical Journal

Background: Increased dietary antioxidant consumption is associated with decreased risk of oxidative stressmediated diseases. Cooking process affects the quantity and quality of antioxidants in foods. In this study, we investigated the antioxidative properties of ready-to-eat (RTE) cooked meals. Objective: To determine the total antioxidant capacity (TAC), total phenolic content (TPC), and total flavonoid content (TFC) in RTE cooked foods and beverages commonly sold in Thailand. Methods: Thirty cooked food items were purchased from local fresh markets and canteens in Bangkok. The foods were categorized into Central food, Northern food, Northeastern food, Southern food, fast food, and beverage. Levels of TAC …