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Articles 31 - 60 of 61
Full-Text Articles in Medicine and Health Sciences
Resilience And Associated Factors Of Family Caregivers Of The Terminal Illness Patients At Cheewabhibaln Center, King Chulalongkorn Memorial Hospital, Kornsiri Pikulthong, Peeraphon Lueboonthavatchai
Resilience And Associated Factors Of Family Caregivers Of The Terminal Illness Patients At Cheewabhibaln Center, King Chulalongkorn Memorial Hospital, Kornsiri Pikulthong, Peeraphon Lueboonthavatchai
Chulalongkorn Medical Journal
Background: Family caregivers play an important role to provide support and care for terminal illness patients by spending their time responding to the patients’ needs. Receiving this role can cause them to be stressful and anxious. Therefore, it is essential for them to have resilience so that they are able to overcome potentially all burdens. Objectives: The present study aimed to examine resilience and associated factors of family caregivers of the terminal illness patients at Cheewabhibaln Center, King Chulalongkorn Memorial Hospital. Methods: This descriptive study was conducted in 150 family caregivers. The sample group was recruited through the purposive sampling …
Compelling Evidence Of Viral Shedding Of Sars-Cov-2 In Stool And Laboratory Safety Suggestion For Stool Examination Amid Covid-19 Era, Nirin Seatamanoch, Switt Kongdachalert, Vivornpun Sanprasert, Narissara Jariyapan, Padet Siriyasatien, Narisa Brownell
Compelling Evidence Of Viral Shedding Of Sars-Cov-2 In Stool And Laboratory Safety Suggestion For Stool Examination Amid Covid-19 Era, Nirin Seatamanoch, Switt Kongdachalert, Vivornpun Sanprasert, Narissara Jariyapan, Padet Siriyasatien, Narisa Brownell
Chulalongkorn Medical Journal
COVID-19 pandemic unfolds in December of 2019 as a number of unknown pneumonia cases arose in Wuhan, China. Patients who contracted the disease usually have respiratory symptoms such as cough and dyspnea. With no established treatment and vaccines, the rise in the number of infections has been unrelenting. SARS-CoV-2 transmits via droplets and aerosols. However, evidence has shown that they are infectious through stools as well. There are increasing numbers of reports of virus particles in feces as well as systematic reviews and meta-analysis to identify the extent of viral fecal excretion. The findings posed a very serious threat upon …
Prevalence And Related Factors Of Musculoskeletal Discomfort Among Pharmacy Personnel Of King Chulalongkorn Memorial Hospital, Wiboon Jiamthubthugsin, Pornchai Sithisarankul
Prevalence And Related Factors Of Musculoskeletal Discomfort Among Pharmacy Personnel Of King Chulalongkorn Memorial Hospital, Wiboon Jiamthubthugsin, Pornchai Sithisarankul
Chulalongkorn Medical Journal
Background: Pharmacy personnel in hospitals are exposed to workplace hazards, especially biomechanical hazards which potentially cause musculoskeletal discomfort (MSD). Understanding of MSD can help prevent and control the problem. Objective: To study the prevalence and related factors of MSD among pharmacy personnel of King Chulalongkorn Memorial Hospital (KCMH). Methods: This study was a cross-sectional descriptive study with a sample size of 197 pharmacy personnel of KCMH. The participants were asked to fill in a self-reported questionnaire comprising of individual and occupational factors and MSD assessed by the modified Nordic questionnaire. Results: The pharmacy personnel have high prevalence of MSD. The …
The Psychometric Property Testing Of The Children’S Yale-Brown Obsessive Compulsive Scale (Cy-Bocs): Thai Version, Wangsuk Wittayapanyanond, Nuttorn Pityaratstian, Napakkawat Buathong
The Psychometric Property Testing Of The Children’S Yale-Brown Obsessive Compulsive Scale (Cy-Bocs): Thai Version, Wangsuk Wittayapanyanond, Nuttorn Pityaratstian, Napakkawat Buathong
Chulalongkorn Medical Journal
Background: Obsessive-compulsive disorder is a disease of various symptoms and severity. In Thailand, currently there is no tool to identify obsessive-compulsive disorder in children and adolescents. Objective: To evaluate the validity and reliability of the Thai version of Children’s Yale-Brown Obsessive Compulsive Scale (CY-BOCS). Methods: This study is a cross-sectional descriptive study to test the content validity of questionnaire using the index of item-objective congruence (IOC) from experts’ opinions and the internal consistency reliability in the sample of 61 child-psychiatrists in secondary, tertiary and psychiatric hospitals in Thailand that assessed children and/or adolescent patients with obsessive compulsive disorder within the …
Effects Of Fenoterol/Ipratropium Bromide On Fev1 And Hyperinflation In Thai Copd Patients, Kamon Kawkitinarong, Anan Ananpipatkul, Nareerat Sae-Eao, Thanin Asawawichienchinda, Worawan Sirichana
Effects Of Fenoterol/Ipratropium Bromide On Fev1 And Hyperinflation In Thai Copd Patients, Kamon Kawkitinarong, Anan Ananpipatkul, Nareerat Sae-Eao, Thanin Asawawichienchinda, Worawan Sirichana
Chulalongkorn Medical Journal
Background: Patients with chronic obstructive pulmonary disease (COPD) usually suffer from breathlessness caused by chronic progressive worsening of airway obstruction and lung hyperinflation. Objective: This study aimed to evaluate the effects of fenoterol hydrobromide and ipratropium bromide combination on lung function parameters in Thai COPD patients. We also compared the effects from two commercially available products; Aerobidol® metered-dose inhaler (MDI) and Berodual® inhaler. Methods: A double-blind, randomized cross-over study was conducted in 31 COPD patients from outpatient service, King Chulalongkorn Memorial Hospital, Bangkok, Thailand. To compare the responses of both inhalers on lung volume parameters, patients were randomized to be …
Effects Of A Telehealth Program On The Functional Status And Rehospitalization Rates Of Patients After Coronary Artery Bypass Grafts, Nattaya Sanonoi, Usavadee Asdornwised, Kessiri Wongkongkam, Teerapong Tocharoenchok
Effects Of A Telehealth Program On The Functional Status And Rehospitalization Rates Of Patients After Coronary Artery Bypass Grafts, Nattaya Sanonoi, Usavadee Asdornwised, Kessiri Wongkongkam, Teerapong Tocharoenchok
Chulalongkorn Medical Journal
Background: Patients with coronary artery bypass graft (CABG) exhibit a decrease in functional status during the postoperative period. The rehospitalization rate within the first month is 8.0% - 21.0%. Therefore, during the first month after discharge, most patients require help from health care teams. Telehealth programs promote health monitoring and share health information remotely during transitional stages, encouraging awareness, increasing cardiac rehabilitation and physical function. As a result, the number of rehospitalizations is also reduced. Objectives: This quasi-experimental research aimed to study the effects of a telehealth program on the functional status and rehospitalization rates of patients with CABG. Methods: …
Utilization Of Hearing Aids For The Underprivileged At Sisaket Hospital Under Thai Red Cross Hearing Aids Project, Kanda Limitlaohaphan
Utilization Of Hearing Aids For The Underprivileged At Sisaket Hospital Under Thai Red Cross Hearing Aids Project, Kanda Limitlaohaphan
Chulalongkorn Medical Journal
Background: As the second-most prevalent disability in Thailand, mitigating the effects of hearing loss can have wide-ranging benefits. Despite the availability of hearing aids, its usage remains low. Objective: This research aimed to study factors related to utilization of hearing aids: age, gender, level of education, degree of hearing loss, understanding of usage and maintenance, and attitudes towards its use. Methods: A cross-sectional study was conducted in 30 hearing loss patients of the Thai Red Cross (TRC) Hearing Aids Project for the Underprivileged, Sisaket Hospital, Sisaket Province, Thailand (here in after referred to as “TRC Hearing Aids Project”) by face-to-face …
Pressure Differences During Foot Reflexology Affect Blood Flow To Brain And Kidneys, Kanokwan Srisupornkornkool, Titipong Kaewlak, Watchara Kaewmahanil, Sompiya Somthavil, Onuma Boonyarom, Kanjana Jittiporn
Pressure Differences During Foot Reflexology Affect Blood Flow To Brain And Kidneys, Kanokwan Srisupornkornkool, Titipong Kaewlak, Watchara Kaewmahanil, Sompiya Somthavil, Onuma Boonyarom, Kanjana Jittiporn
Chulalongkorn Medical Journal
Background: Foot reflexology has been re-emerging as one of the most popular forms of alternative therapy.Although the mechanisms of reflexology have not been apparently understood yet, physiological changes can be found from reflexology, e.g., reduced blood pressure, reduced heart rate, and activated brain functions.However, there are still only a small number of studies on the physiological relationships between foot reflexology and changes in blood flow. Objectives: This investigation aimed to study the effects of brain-associated and kidney-associated foot reflexology on blood flow to the brain and kidneys. The second objective was to examine the effects of pressure differences to reflex …
Association Among Basal Metabolic Rate, Body Composition And Pulmonary Function In University Students, Myat Su Bo, Cheah Whye Lian, Nur Adriana Binti Azhar, Muhammad Ashraf Fraiee Bin Amran, Yeo Deng Xin, Nurazizah Binti Anis
Association Among Basal Metabolic Rate, Body Composition And Pulmonary Function In University Students, Myat Su Bo, Cheah Whye Lian, Nur Adriana Binti Azhar, Muhammad Ashraf Fraiee Bin Amran, Yeo Deng Xin, Nurazizah Binti Anis
Chulalongkorn Medical Journal
Background: Variation in basal metabolic rate (BMR) has been closely related to obesity and pulmonary function. Objectives: To determine the association between BMR, body composition and pulmonary function among university students aged 19 - 22 years old. Methods: This cross-sectional study was carried out among the pre-clinical students of the Faculty of Medicine and Health Sciences, Universiti Malaysia Sarawak. Data was collected using questionnaire, anthropometric measurement, and spirometer. Statistical analysis was performed using IBM SPSS version 20.0. Results: A total of 230 respondents participated in this study. There were 47.7% males and 41.1% females who were overweight and obese, 40.3% …
Depression And Sleep Quality Among Nurses In A Tertiary Hospital In Bangkok, Pariyanuch Junsatitanon, Krit Pongpirul
Depression And Sleep Quality Among Nurses In A Tertiary Hospital In Bangkok, Pariyanuch Junsatitanon, Krit Pongpirul
Chulalongkorn Medical Journal
Background: Currently, depression is a mental health problem that tends to increase. Nurses are one of the healthcare workers that are at risk of depression. The cause of which is due to their heavy workload. In addition, shift work results in decreased sleeps quality. Moreover, research studies on the relationship between sleep quality and depression including other factors are few. Objectives: To investigate the relationship between sleep quality and depression including the prevalence of depression and its associated factors. The recruited subjects of the study were nurses who worked at Nopparat Rajathanee Hospital in 2019. Methods: A cross-sectional survey of …
Factors Predicting Chemotherapy Induced Peripheral Neuropathy In Breast Cancer Patients Receiving Neurotoxic Chemotherapy, Sunet Jiwpanya, Chongjit Saneha, Wimolrat Puwarawuttipanit, Pongwut Danchaivijitr
Factors Predicting Chemotherapy Induced Peripheral Neuropathy In Breast Cancer Patients Receiving Neurotoxic Chemotherapy, Sunet Jiwpanya, Chongjit Saneha, Wimolrat Puwarawuttipanit, Pongwut Danchaivijitr
Chulalongkorn Medical Journal
Background: Cancer is a major cause of death worldwide. Chemotherapy is an effective treatment that is widely used to increase the numbers of cancer survivors. However, it often causes side effects such as nausea, vomiting, and lack of appetite. Chemotherapy induced peripheral neuropathy (CIPN) is one of the most serious side effect leading to fatal outcomes in these patients. Objectives: To examine the influence of patient characteristics (body mass index: BMI, age, and physical activity), clinical characteristic (anemia) and treatment related factors (dosage of neurotoxic chemotherapy) on CIPN in cancer patients receiving neurotoxic chemotherapy. Methods: One hundred and twenty Thai …
Effects Of Customized Foot Orthoses On Lower Limbs Kinematics In Adults With Highly Pronated Foot, Pimwadee Permsombat, Praneet Pensri
Effects Of Customized Foot Orthoses On Lower Limbs Kinematics In Adults With Highly Pronated Foot, Pimwadee Permsombat, Praneet Pensri
Chulalongkorn Medical Journal
Background: Previous studies have assumed that pronated foot may cause mechanical deviations of the lower limbs. Foot orthoses have been used for management to elevate the arch of the foot and alter the kinematic variables during walking. Objective: The purpose of this study was to examine changes in lower limb kinematic variables during the subphases of the gait stance of individuals with highly pronated foot after wearing customized foot orthoses (CFO). Methods: Thirteen adults (five women and eight men, average age 23.3 3.0 years) with asymptomatic highly pronated foot were included in the study. Participants with Foot Posture Index …
Effect Of Using Smartphone Before Bedtime And Sleep Quality Of Middle-Adulthood Officers At Chulalongkorn University, Bhakkhaphorn Booranasuntikul, Naowarat Kanchanakhan
Effect Of Using Smartphone Before Bedtime And Sleep Quality Of Middle-Adulthood Officers At Chulalongkorn University, Bhakkhaphorn Booranasuntikul, Naowarat Kanchanakhan
Chulalongkorn Medical Journal
Background: Nowadays, smartphone has become part of everyday life of the people and tend to be more active continuously. However, it causes many adverse effects, both physically and mentally including potentially resulting in poor sleep quality. Objective: The aim of this study was to investigate the effect of using smartphone before bedtime and sleep quality among the middle-adulthood university officers at Chulalongkorn University. Methods: This cross-sectional descriptive study was conducted among middle-adulthood officers at Chulalongkorn University, aged between 45 - 64 years from 5 faculties within the university. The data were collected by using self-reported questionnaires including general characteristics and …
Effects Of Modified U-Shaped Interspinous Distraction Device On Cadaveric Intervertebral Disc Pressure, Chindanai Hongsaprabhas, Pibul Itiravivong, Pairat Tangpornprasert, Chanyaphan Virulsi
Effects Of Modified U-Shaped Interspinous Distraction Device On Cadaveric Intervertebral Disc Pressure, Chindanai Hongsaprabhas, Pibul Itiravivong, Pairat Tangpornprasert, Chanyaphan Virulsi
Chulalongkorn Medical Journal
Background: Adjacent syndrome is a widely concerned adverse outcome after spinal fusion. Interspinous distraction device (IDD) has become an interesting device and seems to be the solution by theoretically controlling loads to adjacent levels. Objective: To analyze the effects of a modified U-shape IDD on the intervertebral disc (IVD) pressure atm instrumented and adjacent level of a lumbar spine model. Methods: Three cadaveric specimens using lumbar vertebrae level 1 - 5 (L1 - L5) spines were loaded in neutral, flexion and extension. Needle pressure sensor was applied to measure IVD pressure at anterior annulus, nucleus pulposus, and posterior annulus of …
Anxiety Of Students With Visual Impairment In School For Visually Impaired Students In Thailand, Penphitcha Leksaranyaphong, Siriluck Suppapitiporn
Anxiety Of Students With Visual Impairment In School For Visually Impaired Students In Thailand, Penphitcha Leksaranyaphong, Siriluck Suppapitiporn
Chulalongkorn Medical Journal
Background: Anxiety is a prominent cause of mental health issues in students. Studies on this in the visual impairment are limited and none has been conducted in Thailand. The researcher finds that mental health in visually impaired students is significant and the study should be conducted so the data can be used as a tool to plan prevention and help visually impaired students in the future. Objectives: To study anxiety and related factors in visually impaired students. Methods: A cross-sectional descriptive study was conducted in 77 visually impaired students by having them take 2 questionnaires in Braille; basic personal information …
Corticosteroid Injection For Relief Triggering Symptom In Trigger Finger, Kawee Pataradool, Krainon Wasupen
Corticosteroid Injection For Relief Triggering Symptom In Trigger Finger, Kawee Pataradool, Krainon Wasupen
Chulalongkorn Medical Journal
Background: Triggering symptom is a common problem in patients with trigger finger. Corticosteroid has been found to be effective in the treatment of trigger finger, but not clearly defined in the effectiveness of injection in term of relief triggering symptom. Objectives: The purpose of this study was to investigate the effectiveness of corticosteroid injection in term of relief triggering symptom in patients with trigger finger. Methods: We reported 23 patients with a total of 23 fingers, who were treated by corticosteroid injection for treatment of trigger finger. We tested triggering events in ten active fists for evaluation of triggering symptom …
Unusual Position Of Appendix In A Complicated Group Of Children With Acute Appendicitis Causing Midline With Additional Right Lower Quadrant Incision: A Report Of 2 Cases, Vichack Chakrapan Na Ayudhya, Kobkool Chakrapan Na Ayudhya, Paiboon Sookpotarom
Unusual Position Of Appendix In A Complicated Group Of Children With Acute Appendicitis Causing Midline With Additional Right Lower Quadrant Incision: A Report Of 2 Cases, Vichack Chakrapan Na Ayudhya, Kobkool Chakrapan Na Ayudhya, Paiboon Sookpotarom
Chulalongkorn Medical Journal
We reported two cases of acute appendicitis in a complicated group of pediatric patients in which the appendix also located at extraordinary sites. A child aged 5 years old experienced abdominal tenderness with the greatest point at lower abdomen. Another child aged 13 years old suffered from symptoms of abdominal pain. Due to the very young age and presence of full bladder in the former and the underlying cerebral palsy with spasticity in nature in the latter case, finally the diagnosis of appendicitis was established with a great concern. Open appendectomies through Lanz incision were performed in both cases. Since …
Clinical Features And Treatment Outcomes In Obese Children With Appendicitis, Kanokrat Thaiwatcharamas, Paisarn Vejchapipat, Prapapan Rajatapiti, Katawaetee Decharun
Clinical Features And Treatment Outcomes In Obese Children With Appendicitis, Kanokrat Thaiwatcharamas, Paisarn Vejchapipat, Prapapan Rajatapiti, Katawaetee Decharun
Chulalongkorn Medical Journal
Background: Even developing countries are facing problems of childhood obesity. Diagnosis and treatment of appendicitis in obese children can sometimes be challenging. This study compared clinical features and treatment outcomes between non-obese and obese children clinically diagnosed as appendicitis.Methods: Children (0 - 15 years) diagnosed as appendicitis between 2007 and 2013 were reviewed. Children were categorized into non-obese and obese groups using weight for height (> 140.0% of ideal body weight) based on the data of the Ministry of Public Health. Demographic data, clinical data, and treatment outcome were studied. Comparisons between non-obese and obese children were carried out. SPSS …
Fundoplication For Gastroesophageal Reflux In Neurologically Impaired Children: Surgical Perspectives, Furida Salam, Paisarn Vejchapipat, Katawaetee Decharun, Prapapan Rajatapiti, Somboon Roekwibunsi
Fundoplication For Gastroesophageal Reflux In Neurologically Impaired Children: Surgical Perspectives, Furida Salam, Paisarn Vejchapipat, Katawaetee Decharun, Prapapan Rajatapiti, Somboon Roekwibunsi
Chulalongkorn Medical Journal
Background: Gastroesophageal reflux is common in neurologically impaired children due to foregut dysmotility. Most of the patients eventually underwent fundoplication.Objective: This study aimed to describe clinical data and outcome in children with neurological impairment who underwent fundoplication.Methods: Patients (0 - 15 years) with neurological impairment undergoing fundoplication between January 2007 and December 2016 were retrospectively reviewed. Demographic data, surgical complications and short-term outcomes were collected and analyzed.Results: Sixty-five patients (41 boys and 24 girls) underwent open fundoplication over the studied period. There were 21 infants (0 - 1 year, 32.0%), 41 children (1 - 10 years, 63.0%), and 3 adolescents …
Anti-Inflammatory Effect Of Alpha Lipoic Acid Loaded Calcium Citrate Nanoparticle On Human Keratinocyte Hacat Cells, Boonyaras Bukkavesa, Siwaporn Nilyai, Kanidta Sooklert, Sasin Thamakaison, Amornpun Sereemaspun
Anti-Inflammatory Effect Of Alpha Lipoic Acid Loaded Calcium Citrate Nanoparticle On Human Keratinocyte Hacat Cells, Boonyaras Bukkavesa, Siwaporn Nilyai, Kanidta Sooklert, Sasin Thamakaison, Amornpun Sereemaspun
Chulalongkorn Medical Journal
Background: Alpha lipoic acid (LA) is potent anti-oxidant and anti-inflammation natural compound. To enhance the efficacy and stability of LA, LA-loaded calcium citrate nanoparticles were developed.Objective: To investigate the anti-inflammatory effects of LA-loaded calcium citrate nanoparticles (LA-NPs) in HaCaT keratinocytes.Methods: HaCaT cells were exposed under two inflammation stimuli conditions, lipopolysaccharide (LPS) and Pb(NO3)2, and then were treated with or without LA and LA-NPs for 24 h. Cell viability and pattern of cell death were evaluated. In addition, the expression levels of inflammatory cytokines including IL-1β, IL-6, and TNF-α as well as inflammatory mediator COX-2 were determined by real-time polymerase chain …
Anatomical Feature And Early Outcomes Of Endovascular Aneurysm Repair From King Chulalongkorn Memorial Hospital, Kritaya Kritayakirana, Natawat Narueponjirakul, Apinan Uthaipaisanwong, Nantiskarn Chanpen, Punthita Aimsupanimitr
Anatomical Feature And Early Outcomes Of Endovascular Aneurysm Repair From King Chulalongkorn Memorial Hospital, Kritaya Kritayakirana, Natawat Narueponjirakul, Apinan Uthaipaisanwong, Nantiskarn Chanpen, Punthita Aimsupanimitr
Chulalongkorn Medical Journal
Background: Many studies have evaluated anatomy of infrarenal abdominal aortic aneurysm (AAA) and outcomes after endovascular abdominal aneurysm repair (EVAR) but mostly in non-Asian populations. The objective of this study was to evaluate anatomical features and early outcomes for EVAR in the Thai population in a single-center experience.Objective: Treatment of AAA with suitable anatomy has been trending towards EVAR. This study aimed to analyze anatomical features and early outcomes of EVAR in Thai population at King Chulalongkorn Memorial Hospital (KCMH).Methods: Retrospective review of 82 patients who underwent EVAR since January 2012 to December 2016. The medical records were analyzed for …
Lessons Learned From Transnational Joint Doctoral And Cotutelle Doctoral Programs: Strategies For Sustainable Development, Wasee Tulvatana, Thananya Thongtan
Lessons Learned From Transnational Joint Doctoral And Cotutelle Doctoral Programs: Strategies For Sustainable Development, Wasee Tulvatana, Thananya Thongtan
Chulalongkorn Medical Journal
Background: To enhance the global impact, the universities shall ally deeply with their collaborators. Transnational educational programs are crucial modes to build a successful partnership and to make the collaboration sustainable.Objectives: To report and conceptualize the important issues about transnational joint doctoral degree and cotutelle doctoral programs.Methods: We reviewed and conceptualized the lessons learned from joint doctoral degree and cotutelle doctoral programs at the Graduate Affairs, Faculty of Medicine, Chulalongkorn University (CU) during the period of the past 4 years (October 2015 to September 2019).Results: CU launched its first joint doctoral program in 2012. The curriculum was co-built by CU …
Medullary Thyroid Carcinoma In King Chulalongkorn Memorial Hospital: Natural History, Management, And Outcome, Natawat Narueponjirakul, Pasurachate Samorn
Medullary Thyroid Carcinoma In King Chulalongkorn Memorial Hospital: Natural History, Management, And Outcome, Natawat Narueponjirakul, Pasurachate Samorn
Chulalongkorn Medical Journal
Background: Medullary thyroid carcinoma (MTC) is rare and a diagnosis difficulty disease. In term of natural history, management, and outcomes among Thai patients, the data were scarce. Objectives: We aimed to review natural history, management, and clinical outcome of MTC patients in the tertiary care hospital.Methods: Retrospective study of medullary thyroid carcinoma patient was performed in our hospital from January 1, 2002 to December 31, 2011. Medical records has been carefully reviewed. Demographic data, clinical presentation, investigation, management and outcomes has been collected.Results: Sixteen MTC patients were taken into account for 1.1% of all thyroid carcinoma of the hospital, 12 …
Advantage Of Digital Breast Tomosynthesis Combined With Standard Digital Mammography Over Standard Digital Mammography Alone In Surveillance For Local Recurrent Breast Cancer In Patients With Breast Conservative Treatment, Somchanin Pipatpajong, Sarunya Poopongpanich
Advantage Of Digital Breast Tomosynthesis Combined With Standard Digital Mammography Over Standard Digital Mammography Alone In Surveillance For Local Recurrent Breast Cancer In Patients With Breast Conservative Treatment, Somchanin Pipatpajong, Sarunya Poopongpanich
Chulalongkorn Medical Journal
Background: Although breast conserving therapy (BCT) offers more advantages in addition to the competitive survival rate over the traditional treatment of mastectomy, post-BCT surveillance for cancer recurrence remains challenging.Objectives: The purpose of this study was to compare rates of indeterminate findings of standard digital mammography (DM) plus digital breast tomosynthesis (DBT) and DM alone in patients who had undergone BCT at King Chulalongkorn Memorial Hospital, Bangkok, Thailand.Methods: We retrospectively enrolled 150 post-BCT patients who had regular follow-up visits for cancer surveillance by radiological imaging at least for two years at the hospital from January 1, 2013 to December 31, 2014. …
Long-Term Follow Up Of 1,168 Graves’Disease Patients Post Radioiodine Treatment, Soontorn Kraisuwan
Long-Term Follow Up Of 1,168 Graves’Disease Patients Post Radioiodine Treatment, Soontorn Kraisuwan
Chulalongkorn Medical Journal
Background: Current treatments of Graves’ disease have their own advantages and disadvantages. Radioactive Iodine (RAI) is an effective treatment but most of the patients will develop hypothyroidism.Objective: To study the results of treatment of Graves’ disease treated with RAI and to identify factors those could influence the outcomes.Methods: In all, 1,168 Graves’ disease patients who were treated with RAI were evaluated on their thyroid function for 1 - 26 years. The results of treatment were recorded in associated with patient’s gender, age, estimated gland size, pretreatment antithyroid drug and dose of RAI.Results: From 1,168 patients, 939 were females (80.4%), 1,098 …
Does Kasai Operation Prior To Liver Transplantation Affect Peri-Operative Outcomes In Children With Biliary Atresia?, Chatdow Choungboonsri, Pattamon Sutthatarn, Bunthoon Nonthasoot, Booncho Sirichindakul, Wipusit Taesombat, Maythee Sutherasan, Supanit Nivatvongs, Paisarn Vejchapipat
Does Kasai Operation Prior To Liver Transplantation Affect Peri-Operative Outcomes In Children With Biliary Atresia?, Chatdow Choungboonsri, Pattamon Sutthatarn, Bunthoon Nonthasoot, Booncho Sirichindakul, Wipusit Taesombat, Maythee Sutherasan, Supanit Nivatvongs, Paisarn Vejchapipat
Chulalongkorn Medical Journal
Background: Biliary atresia is the most leading cause of death from liver disease in children and the most common indication for pediatric liver transplantation. Although portoenterostomy is the mainstay treatment of biliary atresia, there were some studies found that prior portoenterostomy would adversely affect the liver transplant.Objectives: To compare the peri-operative outcomes between biliary atresia (BA) children having Kasai operation and those with primary liver transplantation (LT).Methods: Children with BA (0 - 15 years) who underwent LT between 2003 and 2017 were reviewed. Patients were categorized into 2 groups (Group A: BA children undergoing Kasai operation prior to liver transplantation; …
Modified Quechers In Blood Sample Preparation For Drug Abuse Determination By Lc-Ms/Ms, Bundhita Boonchaleaw, Nat Tansrisawad, Udomsak Hoonwijit
Modified Quechers In Blood Sample Preparation For Drug Abuse Determination By Lc-Ms/Ms, Bundhita Boonchaleaw, Nat Tansrisawad, Udomsak Hoonwijit
Chulalongkorn Medical Journal
Background: Liquid chromatography-tandem mass spectrometry (LC-MS/MS) becomes a common technique in the routine forensic toxicological analysis because of its accurate result. Solid-phase extraction (SPE) and liquid-liquid extraction (LLE) are the sample preparation methods having disadvantages from time-consuming and using a high quantity of harmful substances. Therefore, modified QuEChERS has been developed for routine toxicological laboratory for simpler sample preparation that could save time and decrease the use of toxic solvent for routine laboratory.Objective: To validate the modified QuEChERS technique for the blood sample preparation and to determine drug abuse in the blood sample using LC-MS/MS.Methods: Amphetamine, methadone, midazolam, morphine and …
High Frequency Repetitive Transcranial Magnetic Stimulation Versus Sertraline In Treatment Of Poststroke Depression: A Pilot Study, Pim Terachinda, Anuphan Tantanatip, Krisna Piravej, Sookjareon Tangwongchai, Sunisa Srioum, Thipwimon Sillapachai, Pisamai Hongsachat, Yuda Chongpison
High Frequency Repetitive Transcranial Magnetic Stimulation Versus Sertraline In Treatment Of Poststroke Depression: A Pilot Study, Pim Terachinda, Anuphan Tantanatip, Krisna Piravej, Sookjareon Tangwongchai, Sunisa Srioum, Thipwimon Sillapachai, Pisamai Hongsachat, Yuda Chongpison
Chulalongkorn Medical Journal
Background: Poststroke depression (PSD) has impact on rehabilitation outcome. Repetitive transcranial magnetic stimulation (rTMS) has been proven as a treatment of depression and might reduce depressive symptoms after stroke.Objectives: To determine the effects of high frequency rTMS in treatment of PSD compared to sertraline. We also investigated the effects of rTMS combined with sertraline.Methods: Fourteen patients with PSD were randomly allocated into 3 groups: 1) the rTMS group received 10 sessions of 10 Hz rTMS; 2) the sertraline group obtained sertraline 50 mg daily and sham rTMS; and, 3) the combined group received 10 Hz rTMS combined with sertraline 50 …
Solid Pseudopapillary Neoplasms Of The Pancreas In Children, Sinobol Chusilp, Katawaetee Decharuna, Paisarn Vejchapipata
Solid Pseudopapillary Neoplasms Of The Pancreas In Children, Sinobol Chusilp, Katawaetee Decharuna, Paisarn Vejchapipata
Chulalongkorn Medical Journal
Solid pseudopapillary neoplasms (SPNs) are very rare pancreatic tumors in children. We present clinical presentation, tumor characteristic, surgical management and outcome of SPNs at our institute. There were four patients (3 males, 1 female) undergoing pancreatectomy for SPNs with median age of 11.5 years (10 - 14 years). Presenting symptoms were abdominal pain (n = 4), palpable abdominal mass (n = 2) and vomiting (n = 2). All patients had tumor located in the pancreatic body, and in two of them, the tumor also involved the pancreatic tail. Three patients underwent distal pancreatectomy and one patient underwent central pancreatectomy. The …
Surgical Management Of Lower Extremity Peripheral Arterial Disease, Natawat Narueponjirakul, Papawee Chennavasin
Surgical Management Of Lower Extremity Peripheral Arterial Disease, Natawat Narueponjirakul, Papawee Chennavasin
Chulalongkorn Medical Journal
Becoming to aging society era, numbers of patients with peripheral arterial disease (PAD) have been continuously increasing. PAD is a presentation of atherosclerotic diseases. Most of the time, the patients are accompanied with underlying diseases that increase risks of atherosclerosis. Treatments of PAD essentially require multidisciplinary team supports. Smoking cessation, controlled exercise program, medical control for underlying diseases must be performed at the beginning of treatments.Revascularizations are indicated in the patients with unbearable symptoms and limb threatening ischemia. The reason why modern endovascular techniques have expeditiously been grown up is its advantage of less invasive and not to burn the …