Medicine and Health Sciences Commons^™

First Case Report Of High Volume Therapeutic Plasma Exchange As A Rescue Therapy In Dengue Hemorrhagic Fever With Acute Liver Failure, Surat Nakaviroj

Chulalongkorn Medical Journal

Acute liver failure is a rare but life-threatening complication of severe dengue infection. Besides standard medical treatment, high volume therapeutic plasma exchange (HV-TPE) is a potential management strategy used to reverse hepatic encephalopathy and coagulopathy. HV-TPE, moreover, improves patient survival from acute liver failure due to paracetamol overdose, viral-induced hepatitis, and Wilson disease. The use of HV-TPE in acute liver failure with dengue hemorrhagic fever has never been reported. We, hereby, report a successful treatment with HV-TPE in acute liver failure with dengue hemorrhagic fever.